The Springer Handbook of Enzymes provides concise data on some 5,000 enzymes sufficiently well characterized - and here is the second, updated edition. Their application in analytical, synthetic and biotechnology processes as well as in food industry, and for medicinal treatments is added. Data sheets are arranged in their EC-Number sequence. The new edition reflects considerable progress in enzymology: the total material has more than doubled, and the complete 2nd edition consists of 39 volumes plus Synonym Index. Starting in 2009, all newly classified enzymes are treated in Supplement Volumes.

This book covers all the basics of managing successful hives, from buying in bee stocks and equipment, to record keeping, establishing and growing colonies, different types of hives, maintaining queens and drones, honey extraction, and diseases. A Lifetime of Beekeeping Mistakes is written from the voice of experience rather than academic research, and is entirely practical, based very much on the right and wrong ways of doing things the author has experienced throughout his beekeeping career.

* Practical approach
* Updated and reoerganized
* New chapter on Communications skills
* Features Exotic pets
* Illustrated throughout in full colour

Intended for dog owners who want to learn more, Canine Behaviour in Mind provides practical ideas that can be incorporated in daily interactions with dogs. Canine Behaviour in Mind presents advice on behavioural change in achievable and creative ways. It examines how the way we live and work with dogs may need adjusting to promote positive behavioural change in the animal as well as better welfare. Case studies with experts are included to guide readers in real-world situations. Scientific research is combined with trainer experience to ensure that the book has science at its heart and provides content of interest to a wide range of dog owners and professionals. Equine Behaviour in Mind by the same editor has garnered some unique reviews. Canine Behaviour in Mind follows the same format, relating dog behaviour to dog ownership.

This book summarises the newest information on seasonal adaptation in animals. Topics include animal hibernation, daily torpor, thermoregulation, heat production, metabolic depression, biochemical adaptations, neurophysiology and energy balance. The contributors to this book present interdisciplinary research at multiple levels ranging from the molecular to the ecophysiological, as well as evolutionary approaches. The chapters of this book provide original data not published elsewhere, which makes it the most up-to-date, comprehensive source of information on these fields.

The book s subchapters correspond to presentations given at the 14th International Hibernation Symposium in August 2012 in Austria. This is a very successful series of symposia (held every four years since 1959) that attracts leading researchers in the field. Like the past symposia, this meeting and consequently the book is aimed not only at hibernation but at covering the full range of animal adaptations to seasonal environments. For the next four years, this book will serve as the cutting-edge reference work for graduate students and scientists active in this field of physiology and ecology.."

Opened during the Great Depression to provide treatment to animals of the poor, Melbourne's Lort Smith Animal Hospital has always owed its survival to the kindness of strangers. In this title, the stories, history, intrigues and historical photographs bring the story of a special institution to life.

Proteomics, like other post-genomics tools, has been growing at a rapid pace and has important applications in numerous fields of science. While its use in animal and veterinary sciences is still limited, there have been considerable advances in this field in recent years, in areas as diverse as physiology, nutrition and food of animal origin processing. This is mainly as a consequence of a wider availability and better understanding of proteomics methodologies by animal and veterinary researchers. This book provides a comprehensive, state-of-the-art account of the status of farm-animal proteomics research, focusing on the principles behind proteomics methodologies and its specific applications and offering clear example.

Situated at the intersection of animal studies and literary theory, this book explores the remarkable and subtly pervasive web of animal imagery, metaphors, and concepts in the work of the Jewish-Italian writer, chemist, and Holocaust survivor Primo Levi (1919-1987). Relatively unexamined by scholars, the complex and extensive animal imagery Levi employed in his literary works offers new insights into the aesthetical and ethical function of testimony, as well as an original perspective on contemporary debates surrounding human-animal relationships and posthumanism. The three main sections that compose the book mirror Levi's approach to non-human animals and animality: from an unquestionable bio-ethical origin ("Suffering"); through an investigation of the relationships between writing, technology, and animality ("Techne"); to a creative intellectual project in which literary animals both counterbalance the inevitable suffering of all creatures, and suggest a transformative image of interspecific community ("Creation").

This book is the first comprehensive, in-depth English language study of the animals that were left behind in the exclusion zone in the wake of the nuclear meltdown of three of the four reactors at the Fukushima Daiichi Nuclear Power Station in March 2011, triggered by the Great East Japan Earthquake of magnitude 9.0.The Japanese government designated an area of 20-kilometer radius from the nuclear power station as an exclusion zone and evacuated one hundred thousand residents, but left companion animals and livestock animals behind in the radioactive area. Consequently, about 90 percent of the animals in the exclusion zone died. This book juxtaposes policies of the Japanese government toward the animals in Fukushima with the actions of grassroots volunteer animal rescue groups that filled the void of the government.

While historiography is dominated by attempts that try to standardize and de-individualize the behavior of animals, history proves to be littered with records of the exceptional lives of unusual animals. This book introduces animal biography as an approach to the re-framing of animals as both objects of knowledge as well as subjects of individual lives. Taking an interdisciplinary perspective and bringing together scholars from, among others, literary, historical and cultural studies, the texts collected in this volume seek to refine animal biography as a research method and framework to studying, capturing, representing and acknowledging animal others as individuals. From Heini Hediger's biting monitor, Hachiko and Murr to celluloid ape Caesar and the mourning of Topsy's gruesome death, the authors discuss how animal biographies are discovered and explored through connections with humans that can be traced in archives, ethological fieldwork and novels, and probe the means of constructing animal biographies from taxidermy to film, literature and social media. Thus, they invite deeper conversations with socio-political and cultural contexts that allow animal biographies to provide narratives that reach beyond individual life stories, while experimenting with particular forms of animal biographies that might trigger animal activism and concerns for animal well-being, spur historical interest and enrich the literary imagination.

This book explores how the ethical treatment and status of other-than-human animals influence pedagogy, teaching, and learning in general, aiming to fill what has been a gap in the philosophy of education. It examines key trends in this regard, including environmental education, humane education, posthumanist education, ecopedagogy, critical animal pedagogy, critical animal studies, animal standpoint theory, and vegan education. The book discusses animal minds and interests, and how animals have been accommodated in moral theory. Further, it investigates whether anti-racist and anti-sexist education logically entail anti-speciesist education and closes by proposing animal rights education as a viable and sound alternative, a pedagogy that does justice not only to animals in general and as species, but also to individual animals. If animal rights education is philosophically and educationally meaningful, then it can arguably offer a powerful pedagogical tool, and facilitate lasting pro-animal changes.

This book explores the religious language of Nonconformity used in ethical debates about animals. It uncovers a rich stream of innovative discourse from the Puritans of the seventeenth century, through the Clapham Sect and Evangelical Revival, to the nineteenth century debates about vivisection. This discourse contributed to law reform and the foundation of the RSPCA, and continues to flavour the way we talk about animal welfare and animal rights today. Shaped by the "nonconformist conscience", it has been largely overlooked. The more common perception is that Christian "dominion" authorises the human exploitation of animals, while Enlightenment humanism and Darwinian thought are seen as drawing humans and animals together in one "family". This book challenges that perception, and proposes an alternative perspective. Through exploring the shaping of animal advocacy discourses by Biblical themes of creation, fall and restoration, this book reveals the continuing importance of the nonconformist conscience as a source to enrich animal ethics today. It will appeal to the animal studies community, theologians and early modern historians.

This work brings together a wealth of data regarding the reference values and factors of variation in biochemical parameters used by camel veterinarians and scientists to determine these animals' nutritional and clinical status. It also explores several technical aspects involved in determining these parameters, sampling procedures, and essential elements in the interpretation of the results. Though many texts are available on small and large ruminants, much less is known about species confined to the marginal zones of tropical and Mediterranean countries, such as camels. This book addresses precisely this research gap, on the one hand by presenting an extensive review of the literature, and on the other by synthesizing the outcomes of the authors' numerous previous works. In veterinary medicine, blood tests to help diagnose diseases in cattle were first proposed nearly a century ago, but were mainly developed in the 1960s, initially at specialized research or veterinary services laboratories, and eventually, with the advent of new equipment and the miniaturization of the analyzers, finding their way into veterinarians' cabinets. Beyond their diagnostic value, veterinary surgeons and zootechnicians also speculated on the potential use of blood tests to evaluate animals' nutritional status. Thus, a whole range of analyses are now proposed to the stakeholders responsible for animal health. Such analyses could help to define a metabolic profile, which would offer a valuable decision-making tool for experts and researchers alike.

When first developed, chlorinated pesticides such as DDT, dieldrin, and mirex were received with open arms, quickly becoming popular as effective, economic agents against pests. But evidence began to mount that residues of these chemicals remained in the environment, not breaking down, often appearing in plants and animals. By the late seventies many pesticides had achieved a terrible notoriety and were subsequently banned in a number of countries. Of tremendous concern, then, is the persistence of pesticides in the environment. The major thrust of research and development in the area of pesticides has properly been the creation of substances that are both effective and degradable. Yet in order to successfully promote the use of biodegradable pesticides, one must fully understand the mechanism of degradation, and it is to this vital subject that we address ourselves in the present volume. According to the Biodegradation Task Force, Safety of Chemicals Com mittee, Brussels (1978), biodegradation may be defined as the molecular degradation of an organic substance resulting from the complex action of living organisms. A substance is said to be biodegraded to an environmentally acceptable extent when environmentally undesirable properties are lost. Loss of some characteristic function or property of substance by biodegradation may be referred to as biological transformation."

In Volume 1 of this series, attention was focused on neuropoisons of animal origin. In the present volume, attention has been shifted to poisons of plant origin. In both cases, we have attempted to identify those poisons for which there is a large measure of clinical or research interest. Our efforts in compiling the series have been aided by three groups of individuals. First, we are grateful to the investigators who contributed chapters. Their labors are the substance of this two-volume work. Second, we are pleased to acknowledge the support of Mr. Seymour Weingarten and Plenum Press in our project. And third, we have been immeasurably aided by our assistants, Mrs. Ruby Hough in New York City and Mrs. Helena Walsh in Canberra. To all these persons, we are indebted. Dr. Lance L. Simpson Dr. David R. Curtis New York City Canberra vii Contents Chapter 1 Reserpine 1 by Theodore A. Slot kin I. Introduction .......................................... .

The Color Atlas of "Xenopus laevis" Histology provides the first central source on the microscopic anatomy of cells, tissues, and major organs of the adult South African clawed frog, Xenopus laevis. For many years, X. laevis has been a highly popular experimental animal model in many areas of research. The recent development of transgenic Xenopus technology offers the promise that this animal model will be utilized more than ever before. The purpose of this book is to provide the active researcher with a central source of high quality light microscopic color images of the tissues of X. laevis, to aid in the identification of the cells and tissues of interest.

Major features of this atlas include:

*277 large, colorful, high resolution light microscopic images of cells, structures, tissues and organs;
*Clear, detailed labeling of important structures in all images;
*Concise, easy-to-read descriptions of histological organization and functions;
*Colorful three-dimensional illustrations that simplify complex structure;
*Detailed presentation of cranial structures and organization;
*Easy-to-use cross-referenced index;
*Bundled CD/ROM containing all images for easy downloading.

Male urogenital glands (also named male accessory sex glands) have received relatively little attention from electron microscopists, with the possible exception of the prostate gland. Moreover, even though comparative studies have clearly shown that these glands exhibit species-dependent features, very few studies, scattered over various publications, are available on the urogenital glands of man. This volume, the 11th of the series on Electron Microscopy in Biology and Medicine, presents an unprecedented collection of information on the functional microanatomy and cytoarchitecture of these organs in humans. Through the integration of transmission and scanning electron microscopy with a variety of modern techniques, it documents the most important aspects of the histophysiology of these glands from their development to some pathological alterations. In order to cover some key mechanisms of their cell biology, such as the action of sex hormones, the epithelio-mesenchymal interactions, and the dynamic of the secretory process, reports on human organs have been supplemented by some studies on experimental animals. The outstanding level of the contributions and the quality of the illustrations make this book, which has been compiled by some of the world authorities on the topic, a work of reference for students, scientists, and professionals interested in biomedical foundations of andrology, as well as a stimulus for future research in this exciting and relatively neglected chapter of human reproduction.

Toph's in Chemical Mutagenesis is a new series dedicated to studies in the areas of environmental chemical mutagenesis and genetic toxicology. In this series we will explore some of many topics that are emerging in these rapidly developing fields. The purpose of the present volume is to attempt to organize and compare the genotoxic properties of the N-nitroso compounds. This is a particularly interesting class of compounds because of the problems encountered with the Salmonella assay of Ames in generating both false positive and false negative results. The battery approach using a number of assay systems seems more appropriate to evaluate chemicals in this class. Topics to be discussed in other volumes in this series include single-cell mutation monitoring systems, the detection of genetic damage in mammalian germ cells, the mutagenicity of pesticides, problems in monitoring human populations in genetic toxicology, and a glossary of terms in genetic toxicology. All of these books are in various stages of development and should appear within the next few years. Frederick J. de Serres Series Editor vii Preface During the past ten years there has been an explosive development in the number of short-term tests to predict the biological risks, especially risks of cancer, in exposure to xenobiotic chemicals. The number of published articles in this area has reached many thousands a year and there are several new journals devoted almost entirely to the presentation of the results obtained in these tests.

This text provides a practical guide providing step-by-step protocol to design and develop vaccines. Chapters detail protocols for developing novel vaccines against infectious bacteria, viruses, fungi, and parasites for humans and animals. Volume 2: Vaccines for Veterinary Diseases includes vaccines for farm animals and fishes, vaccine vectors and production, vaccine delivery systems, vaccine bioinformatics, vaccine regulation and intellectual property. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Vaccine Design: Methods and Protocols, Volume 2: Vaccines for Veterinary Diseases aims to ensure successful results in the further study of this vital field.

Poisons are topics of multidisciplinary concern. The clinician and the pathologist are sensitive to instances of human poisoning. The laboratory researcher, whether pharmacologist, physiologist, or biochemist, is oriented toward molecular modes of poison action. Both clinician and researcher are eager to learn of poisons that can be used as therapeutic agents or methodological tools. This volume is an attempt to underscore the multidisciplinary charac ter of neuropoisons. Six poisons of animal origin which are receiving considerable clinical and research attention are discussed. Each poison is presented first as a clinical entity, then as a topic of investigative research, and finally as an agent useful to the study of nerve function. Because no single volume on neuropoisons can be exhaustive, an attempt at balance is offered as compensation. Two snake venoms, two marine poisons, and two bacterial toxins are presented in detail. In the sequel to this volume, attention will be focused on representative neuro poisons of plant origin."

This publication contains the proceedings of a seminar held in Brussels on November 8-9, 1988. The title of the seminar was "Reducing the costs of disease by improving resistance through genetics." The seminar was held as an activity of the Community Programme for the Coordination of Agricultural Research, 1984-1988. Costs of disease depend on losses caused by morbidity, mortality and production decreases and on the costs of preventive measures including vaccination and medication. Production losses often contribute a major portion to the total costs. To reduce costs of disease preventive measures like vaccination, preventive medication and hygienic procedures are applied. Genetic resistance is an attractive preventive measure because of its consistent nature in the next generations, because it precludes veterinary services and because there are no side-effects. Constraints are the long term investment, relatively slow progress per generation (in combination with production traits) and the considerable lack of knowledge about inheritance of resistance mechanisms in farm animals.

This book provides an extensive review of research into Campylobacter, Helicobacter and Arcobacter species found in poultry. It includes the epidemiology, diagnosis, immune response and disease control of these organisms in commercial poultry production. Antimicrobial resistance, and the incidence and human disease potential of these bacteria is also discussed. A global perspective is presented by experts from four continents - South America, North America, Europe and Africa. This reference work will be of value to the poultry industry, research laboratories, public health workers and students. An extensive overview of the relevant literature is provided by the reference lists at the end of each chapter.

This second volume of papers dealing with scientific and ethical aspects of animal welfare covers a variety of topics and areas of inves tigation. It will be of particular interest to those readers seeking more insight into such subjects as farm animal welfare and humane husbandry systems; animal experimentation, especially in the field of psychology; and pain in animals, notably its recognition and alleviation. Several of our selections deal with very specific subjects that are germane to animal welfare: the use of T-61 for euthanizing cats and dogs, a new humane method of stunning for livestock and poultry, an innovative alternative to killing animals for rabies diagnosis, alterna tives to aversive procedures in teaching experimental psychology, and the need for improved theoretical modeling in animal experimentation and research design. Following the precedent set in the first volume of Advances in Animal Welfare Science, we have included several papers dealing with people's attitudes toward animals. These papers range from a consider ation of cultural influences and veterinary ethics to an examination of anthropomorphism, to a discussion of the linkage between the environ mental politics and perceptions of the Green Movement and animal welfare and rights. We wish to express our gratitude to the Manuscript Review Commit tee for the excellent work they have done and to the twenty contributors to this volume which we believe will do much to advance the science of animal welfare, and the well-being of animals under man's dominion."