The Theory of Endobiogeny Volume 2: Foundational Concepts for Treatments of Common Clinical Conditions addresses the core elements of the adaptation response to stressors: autonomic nervous system (ANS), corticotropic axis, immunity and digestive tract function. The volume is oriented for clinical practice, offering clear discussions on treating the root cause of numerous common disorders, and symptomatically addressing the destabilizing factor in a vast number of disorders ranging from depression to irritable bowel, and from migraines to insomnia called spasmophilia.

The Theory of Endobiogeny Volume 1: Global Systems Thinking and Biological Modeling for Clinical Medicine offers researchers and clinicians a detailed introduction to the theory of Endobiogeny. The book presents a new approach to medicine that is at once scientific and humanistic, quantitative, and qualitative. The philosophical and experimental basis of a global complex systems approach to physiology is presented along with a mathematical approach to modeling the dynamism of the terrain. The importance of the history and physical examination are renewed as a source of "big data" readily available to clinicians for greater insight into the patient's state. Expansion of the therapeutic compendium is proposed based on a rational, clinical approach correlated to mathematical indicators of the physiologic state. What is proposed in this work is a fundamental shift in scientific thinking with a resulting expansion of the boundaries of clinical medicine for the 21st century and beyond.

In this issue of Neuroimaging Clinics, guest editor Dr. Tarik F. Massoud brings his considerable expertise to the topic of Neuroimaging Anatomy, Part 1: Brain and Skull. Anatomical knowledge is critical to reducing both overdiagnosis and misdiagnosis in neuroimaging. This issue is part one of a two-part series on neuroimaging anatomy that focuses on the brain, with each article addressing a specific area. The issue also includes an article on Brain Connectomics: the study of the brain's structural and functional connections between cells. Contains 13 relevant, practice-oriented topics including anatomy of cerebral cortex, lobes, and the cerebellum; brainstem anatomy; cranial nerves anatomy; brain functional imaging anatomy; imaging of normal brain aging; and more. Provides in-depth clinical reviews on neuroimaging anatomy of the brain and skull, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Molecules to Medicine with mTOR: Translating Critical Pathways into Novel Therapeutic Strategies is a one-stop reference that thoroughly covers the mechanistic target of rapamycin (mTOR). mTOR, also known as the mammalian target of rapamycin, is a 289-kDa serine/threonine protein kinase that is ubiquitous throughout the body and has a critical role in gene transcription and protein formation, stem cell development, cell survival and senescence, aging, immunity, tissue regeneration and repair, metabolism, tumorigenesis, oxidative stress, and pathways of programmed cell death that include apoptosis and autophagy. Incorporating a translational medicine approach, this important reference highlights the basic cellular biology of mTOR pathways, presents the role of mTOR during normal physiologic function and disease, and illustrates how the mechanisms of mTOR can be targeted for current and future therapeutic treatment strategies. Coverage of mTOR signaling includes the entire life cycle of cells that impacts multiple systems of the body including those of nervous, cardiovascular, immune, musculoskeletal, endocrine, reproductive, renal, and respiratory origin.

Written by leaders in the field of chemosensation, Chemosensory Transduction provides a comprehensive resource for understanding the molecular mechanisms that allow animals to detect their chemical world. The text focuses on mammals, but also includes several chapters on chemosensory transduction mechanisms in lower vertebrates and insects. This book examines transduction mechanisms in the olfactory, taste, and somatosensory (chemesthetic) systems as well as in a variety of internal sensors that are responsible for homeostatic regulation of the body. Chapters cover such topics as social odors in mammals, vertebrate and invertebrate olfactory receptors, peptide signaling in taste and gut nutrient sensing. Includes a foreword by preeminent olfactory scientist Stuart Firestein, Chair of Columbia University's Department of Biological Sciences in New York, NY. Chemosensory Transduction describes state-of-the-art approaches and key findings related to the study of the chemical senses. Thus, it serves as the go-to reference for this subject for practicing scientists and students with backgrounds in sensory biology and/or neurobiology. The volume will also be valuable for industry researchers engaged in the design or testing of flavors, fragrances, foods and/or pharmaceuticals.

"Integrative Anatomy and Pathophysiology in Traditional Chinese Medicine Cardiology" covers the structure, function, and pathology of the cardiovascular system from the TCM and western medical perspectives. It focuses specifically on western medicine anatomy and pathophysiology, along with TCM aspects of essence, qi, blood and body fluid concepts, production, and function to explain cardiovascular system dysfunction, its independent role and dependent interactions with the functions of other organ systems.

This book is designed for US-based licensed TCM practitioners as well as cardiology researchers.
Compares and contrasts the TCM basic theories and western medicine basic sciencesGives a specific connection between the heart dysfunction and the disease mechanisms of other organ systems using TCM and western medicine terms and diagnosesPrepares the practitioner to sit for the Niambi Wellness Integrative Anatomy and pathophysiology in cardiology final online exam

A successful Wall Street trader turned neuroscientist reveals how risk taking and stress transform our body chemistry
Before he became a world-class scientist, John Coates ran a derivatives trading desk in New York City. He used the expression "the hour between dog and wolf" to refer to the moment of Jekyll-and-Hyde transformation traders passed through when under pressure. They became cocky and irrationally risk-seeking when on a winning streak, tentative and risk-averse when cowering from losses. In a series of groundbreaking experiments, Coates identified a feedback loop between testosterone and success--one that can cloud men's judgment in high-pressure decision-making. Coates demonstrates how our bodies produce the fabled gut feelings we so often rely on, how stress in the workplace can impair our judgment and even damage our health, and how sports science can help us toughen our bodies against the ravages of stress. Revealing the biology behind bubbles and crashes, "The Hour Between Dog and Wolf "sheds new and surprising light on issues that affect us all.

Human Growth and Development, Third Edition provides a comprehensive volume covering the biology of human growth and the genetic, endocrine, environmental, nutritional, and socio-economic factors that contribute towards its full expression. Human Growth and Development continues to be a valuable resource for researchers, professors and graduate students across the interdisciplinary area of human development. For the new edition, updates are made to all fourteen of the "core chapters" of the book which form the essential reading for a comprehensive understanding of human growth and development. Additionally, new special topics are covered including the interpretation of recently found sub-adult fossils that expand our understanding of the evolution of human growth and a discussion of the early pattern of growth and development as the developmental origins of risk for non-communicable diseases of adulthood. Human Growth and Development, Third Edition includes contributions from the well-known experts in the field and is the most reputable, comprehensive resource available.

Food and water are necessary for survival, but can only be obtained via ingestive behavior (feeding, drinking, and moving). Survival thus depends on the ability of the brain to coordinate the need for water and energy with appropriate behaviors to modify their intake as necessary for homeostasis. However, the balance of these behaviors also inherently determines body weight, and imbalances contribute to the development of weight disorders, such as obesity and anorexia nervosa. The lateral hypothalamic area (LHA) of the brain is anatomically positioned to coordinate the sensation of osmotic and energy status with goal-directed ingestive behaviors necessary to maintain homeostasis and body weight, and, hence, may hold insight into the potential treatment for energy balance disorders. This volume reviews the essential role of the LHA for the control of body weight, from its historical description as a ""feeding center"" to the current view of this LHA as a cellularly heterogeneous hub that regulates multiple aspects of physiology to influence body weight. Furthermore, we evaluate how specific LHA populations coordinate certain metabolic cues and behaviors, which may guide the development of pathway-specific interventions to improve the treatment of energy balance disorders.

The definitive anatomical coloring book is now back and freshened up with a new cover. Each year, thousands of students studying to be doctors, physical therapists, and medical technicians have to master the art of anatomy--and prospective artists also want to capture realistic movement and posture. What better way to remember each bone, muscle, and organ than by coloring a picture? The very act of drawing entices students to spend more time with the image, and to examine the body's structure more closely. That's why this one-of-a-kind coloring book, with its concisely written text and easy-to-color-in medical illustrations, has always been such a huge seller--and why it's now revised into this new user-friendly format. Arranged according to body systems, the color-key organization links anatomical terminology to the more than 1,000 precise and detailed black-and-white illustrations.

This book provides therapists with the background knowledge they require before they can safely and accurately treat patients with musculoskeletal disorders of the spine. Thoroughly referenced and extensively illustrated with over 200 specially prepared and original diagrams of the highest quality, Functional Anatomy of the Spine will be invaluable to the student and practitioner physiotherapists, chiropractors and osteopaths, and indeed to all those who regularly treat spinal dysfunction. Accessory and physiological spinal movements are thoroughly described. Palpation is covered in detail. Numerous guidelines for safe practice are provided. A valuable, comprehensive chapter covers posture, lifting, and the prevention of injury. Coverage of applied anatomy and biomechanics is written by therapists for therapists. New theories on thoracic biomechanics are presented, rarely covered by other anatomy books. All topics have been updated to reflect recent scientific evidence, enabling the reader to more effectively formulate and manage treatment plans. New illustrations to complement the text and improve readers' understanding of the material. A one-of-a-kind chapter covering the sacroiliac joint has been comprehensively revised. Expanded material is provided on the autonomic nervous system, thoracic spine biomechanics, and the biomechanics of the lower limb as it relates to the spine. New sections address adverse neural tension, cervical discs, proprioception and muscle imbalance, and mechanics of the jaw and upper cervical spine. An update on vertebral artery and blood supply presents the latest knowledge on the subject.