This edited book explores the use of technology to enable us to visualize the life sciences in a more meaningful and engaging way. It will enable those interested in visualization techniques to gain a better understanding of the applications that can be used in visualization, imaging and analysis, education, engagement and training. The reader will also be able to learn about the use of visualization techniques and technologies for the historical and forensic settings. The reader will be able to explore the utilization of technologies from a number of fields to enable an engaging and meaningful visual representation of the biomedical sciences. We have something for a diverse and inclusive audience ranging from healthcare, patient education, animal health and disease and pedagogies around the use of technologies in these related fields. The first four chapters cover healthcare and detail how technology can be used to illustrate emergency surgical access to the airway, pressure sores, robotic surgery in partial nephrectomy, and respiratory viruses. The last six chapters in the education section cover augmented reality and learning neuroanatomy, historical artefacts, virtual reality in canine anatomy, holograms to educate children in cardiothoracic anatomy, 3D models of cetaceans, and the impact of the pandemic on digital anatomical educational resources.

This book is the first photographic and descriptive musculoskeletal atlas of Hylobates, and adopts the same format as the photographic atlas of Gorilla published by the same authors in 2010. These two books are part of a series of monographs that will set out the comparative and phylogenetic context of the gross anatomy and evolutionary history of the soft tissue morphology of modern humans and their closest relatives. This atlas, which includes detailed high-quality photographs of musculoskeletal structures from most anatomical regions of the body as well as textual information about the attachments, innervation and weight of the respective muscles, is based on dissections and on an extensive review of the literature. It provides an updated review of the anatomical variations within hylobatids as well as an extensive list of the synonyms used in the literature to designate the structures we discuss. The atlas will be of interest to students, teachers and researchers studying primatology, comparative anatomy, functional morphology, zoology, and physical anthropology and to medical students, doctors and researchers who are curious about the origin, evolution, homology and variations of the musculoskeletal structures of modern humans.

Functional Awareness: Anatomy in Action for Dancers is where anatomy meets artistry. Each chapter provides explorations in embodied anatomy in an engaging manner with the use of images, storytelling, and experiential exercises. It is an accessible introduction to the relationship between daily movement habits, dance training and anatomy. The information is founded on over 30,000 hours of experience teaching and training dancers to generate efficient exertion and appropriate recuperation. Functional Awareness: Anatomy in Action for Dancers employs somatic practices along with explorations in experiential anatomy to awaken the body-mind connection and improve movement function. The book applies the Functional Awareness (R) approach to improve dance technique and provide skills to enable the dancer to move with balance and grace in the classroom, on stage, and in daily life.

Now in its third edition, Anatomy in Diagnostic Imaging is an unrivalled atlas of anatomy applied to diagnostic imaging. The book covers the entire human body and employs all the imaging modalities used in clinical practice; x-ray, CT, MR, PET, ultrasound and scintigraphy. An introductory chapter explains succinctly the essentials of the imaging and examination techniques drawing on the latest technical developments. In view of the great strides that have been made in this area recently, all chapters have been thoroughly revised in this third edition. The book s original and didactically convincing presentation has been enhanced with over 250 new images. There are now more than 900 images, all carefully selected in order to be user-friendly and easy-to-read, due to their high quality and the comprehensive anatomical interpretation directly placed alongside every one. Both for medical students and practising doctors, Anatomy in Diagnostic Imaging will serve as the go-to all-round reference collection linking anatomy and modern diagnostic imaging. Winner of the Radiology category at the BMA Book Awards 2015

First published in 1967, Human Guinea Pigs is a report by a consultant physician on the implications of medical research on both the medical profession and on the men, women and children who are the subjects of medical experiments. It suggests that there are limits to the permissibility of experiments on humans. It points out how it has become a common occurrence for medical investigators to take risks with patients of which the patients themselves are frequently unaware, and to submit them to mental and physical distress and possible hazards which in no way are necessitated by or have connection with the treatment of the disease from which are suffering. The author describes a number of experiments which, in his opinion, raise important problems. In his view, medical research must go on, but there must be acknowledged and observed safeguards for patients. This book will be of interest to students of medicine, ethics, law, politics and social work.

Resistance arteries have been recognized for some time as key factors in the regulation of vascular flow resistance, where they determine the regional and local distribution of blood and arterial pressure. Chapters provide an overview of the physiological, biochemical, and electrophysiological characteristics of these vessels, as well as a critical evaluation of the methodologies for studying small arteries and an examination of the membrane and neural mechanisms involved in the control of vascular tone.

The heart-wrenchingly honest and fascinating new book from forensic pathologist and bestselling author of UNNATURAL CAUSES, Dr Richard Shepherd A TIMES AND SUNDAY TIMES BOOK OF THE YEAR 'Each chapter is like a finely-crafted detective story . . . Shepherd writes beautifully, and despite its subject, the book is very funny in parts' DAILY TELEGRAPH 'Enlightening, strangely uplifting . . . Shepherd's final chapter on death itself is a meditation of great beauty and light which puts all the darkness of the previous pages into perspective' DAILY MAIL 'Deeply insightful. Unflinching' THE TIMES 'Fascinating' DAILY EXPRESS 'This book is about death, but in it I will take readers on a journey through life . . .' _________ Dr Richard Shepherd, Britain's top forensic pathologist, has spent a lifetime close to the dead. As a medical detective, each autopsy he carries out is its own unique investigation, uncovering the secrets not only of how a person died, but also of how they lived. Through twenty-four of his most intriguing, enlightening and never-before-told cases, Dr Shepherd shares autopsies that span the seven ages of human existence, and have taught him as much about the marvels of life as the inevitability of death. From old to young, from murder to misadventure, and from illness to accidental death, each of these bodies has something to reveal: about human development, about mortality, about its owner's life story, about justice and even about Shepherd himself. From the bestselling author of Unnatural Causes comes a powerful, moving and above all reassuring book about death as it touches our own lives - how to understand it, and, when our time comes (as it must), how to embrace it as the last great adventure. _________ 'He has the ability to examine himself and other people with the same forensic eye that he applies to corpses - one of the reasons why his books feel so life-enhancing' Daily Telegraph Praise for Dr Richard Shepherd 'Gripping, grimly fascinating, and I suspect I'll read it at least twice' Evening Standard 'A deeply mesmerising memoir of forensic pathology. Human and fascinating' Nigella Lawson 'An absolutely brilliant book. I really recommend it, I don't often say that but it's fascinating' Jeremy Vine, BBC Radio 2 'Puts the reader at his elbow as he wields the scalpel' Guardian 'Fascinating, gruesome yet engrossing' Richard and Judy, Daily Express 'Fascinating, insightful, candid, compassionate' Observer

This is the only in-depth, single author survey of heart development. It will provide a more systematic, up-to-date synthesis of the subject than any other volume, spanning the range from classical anatomical studies to recent findings in molecular biology. It also covers topics that are often omitted from discussions of heart development, such as myocardial function, cardiac innervation, and conduction development and clinical correlates will be discussed throughout. The book is beautifully illustrated by Karen Waldo, an artist who has collaborated with Dr. Kirby for many years.

This volume presents a series of protocols and methods, some of which are not widely used by researchers/practitioners, and will aid in the execution of different laboratory techniques. Forensic DNA Typing Protocols, Second Edition is arranged into a series of related chapters. Chapter 1-3 examines two different aspects of RNA analysis for body fluid identification. Chapters 4-7 focuses on the storage of biological materials and the extraction of DNA from hard tissues. Chapters 8-10 present methods for monitoring the quality of DNA extracts, and steps to aid in the purification of DNA. Chapters 11-16 talk about methods on non-standard markers, such as INDELs, Y chromosome STRs, and mitochondrial DNA. Detailed procedures and data analysis for phenotypes and ancestry are explored in Chapter 17-19. The last chapter (20) looks at the application of DNA typing to the identification of non-human material to species level. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and thorough, Forensic DNA Typing Protocols, Second Edition, is a valuable resource for forensic specialists, researchers, and anyone interested in the field of forensic science.

Bundle includes: 9781119576488 Fundamentals of Anatomy and Physiology: For Nursing and Healthcare Students, 3rd Edition A concise yet comprehensive introduction to the structure and function of the human body. Written with the needs of nursing and healthcare students in mind, this best-selling textbook incorporates clinical examples and scenarios throughout to illustrate how the topics covered are applied in practice. Hundreds of full-colour illustrations complement numerous case studies encompassing all fields of nursing practice, alongside learning outcomes, self-assessment tests and other effective learning tools. 9781119699491 Fundamentals of Applied Pathophysiology: An Essential Guide for Nursing and Healthcare Students, 4th Edition A highly visual and accessible introduction to pathophysiology for nursing and healthcare students, including brand-new content on homeostasis, a systematic approach to assessment, and key terminology. The book features links to clinical observations, vital signs to observe, investigation boxes, clinical red flags, medication alerts, and the latest, contemporary evidence for care management, including National Early Warning Score 2 (NEWS2).

This detailed volume focuses on population epigenetics, which is of increasing interest to policy makers searching for explanations for complex epidemiological observations and conceptual models on which to base interventions. With a concentration on DNA methylation, the emphasis is on the most commonly studied epigenetic phenomenon that is most amenable to further study. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Population Epigenetics: Methods and Protocols aims to aid population researchers in exploiting the latest insights into epigenetics to improve our understanding of the factors that influence human health and longevity.

The book provides an updated overview of molecular analysis of human tissues, and the impact this analysis has on diagnosis and prognosis of human diseases. Special emphasis is placed on human cancer and the future directions of the field. Methods of handling clinical tissue samples, including the impact of handling on subsequent molecular analysis, are also discussed. In addition, detailed protocols for molecular analysis of DNA, RNA and protein, with special emphasis on molecular analysis of highly complex human tissue samples containing mixtures of cell populations, are provided.

1) Classic anatomical atlases 2) Detailed labelling of the earliest phases of prenatal neurological development without abbreviations 3) Appeals to neuroanatomists, developmental biologists and clinical practioners 4) Persistent relevance - brain development is not going to change, but this Atlas offers updated terminology for primordial neural structures.

This third of 15 short atlases reimagines the classic 5-volume Atlas of Human Central Nervous System Development. This volume presents serial sections from specimens between 15 mm and 18 mm with detailed annotations, together with 3D reconstructions. An introduction summarizes human CNS development by using high-resolution photos of methacrylate-embedded rat embryos at a similar stage of development as the human specimens in this volume. The accompanying Glossary gives definitions for all the terms used in this volume and all the others in the Atlas. Features Classic anatomical atlas Detailed labeling of structures in the developing brain offers updated terminology and the identification of unique developmental features, such as germinal matrices of specific neuronal populations and migratory streams of young neurons Appeals to neuroanatomists, developmental biologists, and clinical practitioners A valuable reference work on brain development that will be relevant for decades

During the past decade, great strides have been made in our un derstanding of the biochemistry and pharmacology of the alpha-l adrenergic receptor. The alpha-l adrenergic receptor plays a key role in biological function. This is evidenced by the fact that the alpha-l adrenergic receptor plays a prominent functional role in most organs of the body and in the key systems responsible for survival of the organism and maintenance of optimum biological activity. This is most apparent in the cardiovascular system, in which alpha-l adrenergic receptors are the single most important receptor involved in the maintenance of blood pressure and circu latory function. It is appropriate, therefore, that recent findings related to the pharmacology and biochemistry of the alpha-l adrenergic receptor be compiled, since this subject has not been reviewed in detail in recent years. It is the purpose of this book to present a series of reviews of key experimental findings that shed new light on the alpha-l adrenergic receptor and the manner in which it functions. Classically, most receptors have been characterized based on structure-activity relationships obtained for selective agonists and antagonists interacting with the receptor. Although there are many newer and more sophisticated approaches to receptor char acterization, structure-activity relationships still provide impor tant information regarding the chemical requirements made by the receptor for its occupation by ligands and its subsequent acti vation by those ligands possessing intrinsic efficacy and, there fore, agonist activity."

The Geometric Induction of Bone Formation describes new biomimetic biomaterials that offer mechanistic osteogenic surfaces for the autonomous and spontaneous induction of bone formation without the addition of osteogenic soluble molecular signals of the transforming growth factor- supergene family. The chapters frame our understanding of regenerative medicine in primate species, including humans. The goal is to unravel the fundamental biological mechanisms of bone formation unique to non-human and human primates. The broad target audience dovetails with several disciplines both in the academic and private biotech sectors primarily involved in molecular biology, tissue biology, tissue engineering, biomaterial science, and reconstructive, orthopedic, plastic, and dental surgery. Key Features Includes outstanding images of undecalcified whole mounted sections Summarizes non-human primate research - ideal for clinical translation Reviews methods for creating devices capable of making bone autonomously, i.e. an intrinsically osteo-inductive bioreactor and/or biomaterial Describes the spontaneous induction of bone formation including a whole spectrum of tissue biology, from basic molecular biology to clear-cut morphology and pre-clinical application in non-human primate species Intended for audiences in both academic research and the biotech industry

This chart illustrates spinal nerves and cranial nerves and diagrams the portion of the thoracic spinal cord with spinal nerves. It also shows spinal cord segments, cutaneous distribution of spinal nerves, and dermal segmentation.

Developed in response to student and faculty feedback worldwide, Gray's Basic Anatomy is a concise, easy-to-read text known for its utility and clarity, relevant and accurate content, strong clinical focus, and interactive online features. Perfect for readers who need an efficient, high-yield anatomy text, the fully updated 3rd Edition covers the key anatomical concepts that students need to know, all superbly illustrated with full-color artwork. Using a progressive and accessible approach, it provides a practical foundation of anatomical knowledge in a time-saving, highly understandable manner. Offers readable, concise and complete anatomy coverage with true-to-life illustrations and useful clinical examples Features fully revised and updated content throughout, including new non-binary information, equal coverage of male and female anatomy, and surface anatomy illustrations that reflect people of color. Integrates anatomy with current modes of imaging, clinical material, and surface anatomy. Includes a Conceptual Overview in each chapter that introduces readers to basic concepts of that region-now supplemented by additional simplified schematic diagrams for key structures. Incorporates superb artwork that includes select views from the wider Gray's family of texts. Contains updated classification of cranial nerves and new references to lymphatics associated with the central nervous system. Features outstanding electronic ancillaries, including a new bonus e-chapter on neuroanatomy essentials, an interactive surface anatomy tool, self-assessment questions, additional clinical and PT cases, and more. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

This book brings together current advances in high-technology visualisation and the age-old but science-adapted practice of drawing for improved observation in medical education and surgical planning and practice. We begin this book with a chapter reviewing the history of confusion around visualisation, observation and theory, outlining the implications for medical imaging. The authors consider the shifting influence of various schools of philosophy, and the changing agency of technology over time. We then follow with chapters on the practical application of visualisation and observation, including emerging imaging techniques in anatomy for teaching, research and clinical practice - innovation in the mapping of orthopaedic fractures for optimal orthopaedic surgical guidance - placental morphology and morphometry as a prerequisite for future pathological investigations - visualising the dural venous sinuses using volume tracing. Two chapters explore the use and benefit of drawing in medical education and surgical planning. It is worth noting that experienced surgeons and artists employ a common set of techniques as part of their work which involves both close observation and the development of fine motor skills and sensitive tool use. An in-depth look at police identikit construction from memory by eyewitnesses to crimes, outlines how an individual's memory of a suspect's facial features are rendered visible as a composite image. This book offers anatomy educators and clinicians an overview of the history and philosophy of medical observation and imaging, as well as an overview of contemporary imaging technologies for anatomy education and clinical practice. In addition, we offer anatomy educators and clinicians a detailed overview of drawing practices for the improvement of anatomical observation and surgical planning. Forensic psychologists and law enforcement personnel will not only benefit from a chapter dedicated to the construction of facial composites, but also from chapters on drawing and observation.

Remarkable atlas provides exceptionally detailed, clinically relevant anatomic knowledge! Thieme Atlas of Anatomy: General Anatomy and Musculoskeletal System, Third Edition, Latin Nomenclature, by renowned educators Michael Schuenke, Erik Schulte, and Udo Schumacher, along with consulting editors Nathan Johnson and Hugo Zeberg, expands on the award-winning prior editions with updated spreads and added information on joints, muscle actions, and functional muscle groups. Organized by region, the book begins with an introduction on basic human embryology and development and an overview of the human body. Subsequent general anatomy chapters explore surface anatomy, the bones, joints, muscles, vessels, lymphatic system and glands, and general neuroanatomy. The next section delineates the trunk wall, functional musculature, and the neurovascular system, while the last two sections are dedicated to the upper limb and lower limb. Key Features Labels and anatomic terminology are in Latin nomenclature Nearly 2,100 images including extraordinarily realistic illustrations by Markus Voll and Karl Wesker, X-rays, MRIs, CT scans, diagrams, tables, and descriptive text provide an unparalleled wealth of information about muscle structure and bones Musculoskeletal, vascular, and nervous system structures are presented systematically first, then topographically, thereby supporting classroom learning and active laboratory dissection Emphasizes important relationships between anatomic structure and function in addition to introducing clinical applications, providing knowledge trainees can apply in practice Online images with "labels-on and labels-off" capability are ideal for review and self-testing This visually stunning atlas is a must have for medical, allied health, and physical therapy students, instructors, and practicing physical and massage therapists. It is also a wonderful anatomic reference for professional artists and illustrators. The THIEME Atlas of Anatomy series also includes two additional volumes, Internal Organs and Head, Neck, and Neuroanatomy. All volumes of the THIEME Atlas of Anatomy series are available in softcover English/International nomenclature and in hardcover with Latin nomenclature. This book includes complimentary access to a digital copy on https://medone.thieme.com.

Written by leaders in the field of chemosensation, Chemosensory Transduction provides a comprehensive resource for understanding the molecular mechanisms that allow animals to detect their chemical world. The text focuses on mammals, but also includes several chapters on chemosensory transduction mechanisms in lower vertebrates and insects. This book examines transduction mechanisms in the olfactory, taste, and somatosensory (chemesthetic) systems as well as in a variety of internal sensors that are responsible for homeostatic regulation of the body. Chapters cover such topics as social odors in mammals, vertebrate and invertebrate olfactory receptors, peptide signaling in taste and gut nutrient sensing. Includes a foreword by preeminent olfactory scientist Stuart Firestein, Chair of Columbia University's Department of Biological Sciences in New York, NY. Chemosensory Transduction describes state-of-the-art approaches and key findings related to the study of the chemical senses. Thus, it serves as the go-to reference for this subject for practicing scientists and students with backgrounds in sensory biology and/or neurobiology. The volume will also be valuable for industry researchers engaged in the design or testing of flavors, fragrances, foods and/or pharmaceuticals.

Lysosomes are key subcellular organelles that regulate the cell function. Many of the essential activities of the cell are dependent on lysosomes. Dysfunction is linked to multiple diseases - storage disorders, neurodegeneration, immunological diseases and cancer. This book discusses concepts and methods used to study lysosome ion and small molecule transport. The contents will not only attract accomplished investigators in need of a broad review and synthesis of this important subject but will also appeal to young investigators and trainees needing to acquire comprehensive knowledge and technical skills working with lysosomal ion channels and small molecule transporters. Key selling features: Summarizes the endocellular role that lysosomes play with respect to cellular waste disposal Reviews essential cellular functions of lysosomes Explores how lysosome dysfunction is the cause of many metabolic disorders Examines how lysomes are involved in storage diseases Describes various technologies and methods used in lysosome research