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Books > Medicine > Pre-clinical medicine: basic sciences > Anatomy > General

The Human Brain During the First Trimester - Atlas of Human Central Nervous System Development, Volume 1-7 (Paperback): Shirley... The Human Brain During the First Trimester - Atlas of Human Central Nervous System Development, Volume 1-7 (Paperback)
Shirley A. Bayer, Joseph Altman
R7,593 Discovery Miles 75 930 Ships in 12 - 19 working days

This set includes Volumes 1-7 of 15 short atlases reimagining the classic 5 volume Atlas of Human Central Nervous System Development. A handy paperback edition completes the coverage of the first trimester of human brain development. Serial sections from specimens between 4mm and 60mm are illustrated and annotated in great detail, together with 3D reconstructions. An introduction and glossary summarize these earliest stages of human Central Nervous System development. Key Features 1) Classic anatomical atlases 2) Detailed labeling of the earliest phases of prenatal neurological development 3) Appeals to neuroanatomists, developmental biologists and clinical practitioners. 4) Persistent relevance - brain development is not going to change.

Physiology of Human Female Lactation (Hardcover, 1st ed. 2021): Nikolai Petrovitch Alekseev Physiology of Human Female Lactation (Hardcover, 1st ed. 2021)
Nikolai Petrovitch Alekseev
R4,854 Discovery Miles 48 540 Ships in 10 - 15 working days

This comprehensive Monograph examines all peripheral and central mechanisms of regulating the secretion of milk from the lactating breast. The author reviews the complete female breast development, starting with the early childhood, up to pregnancy and lactation. Structural and ultrastructural data on the alveolar-ductal system, together with details of breast innervation, are used to investigate the physiological process of lactation. Readers will appreciate the special focus on reflexes, both in the child and the mother, that help to regulate maternal milk production and secretion. Following this, the author sheds a light on the composition and dynamics of milk components during the different periods of lactation. The final section of this volume focusses on practical aspects of modern breastfeeding, like the use of breast pumps or galactogogues, to influence the productivity of milk production. These fundamental principles and structural details will be particularly useful for physiologists and clinicians working in gynecology and pediatrics.

Learning the Hard Way - Masculinity, Place and the Gender Gap in Education (Hardcover, New): Edward W. Morris Learning the Hard Way - Masculinity, Place and the Gender Gap in Education (Hardcover, New)
Edward W. Morris
R3,226 Discovery Miles 32 260 Ships in 12 - 19 working days

An avalanche of recent newspapers, weekly newsmagazines, scholarly journals, and academic books has helped to spark a heated debate by publishing warnings of a "boy crisis" in which male students at all academic levels have begun falling behind their female peers. In Learning the Hard Way, Edward W. Morris explores and analyzes detailed ethnographic data on this purported gender gap between boys and girls in educational achievement at two low-income high schools-one rural and predominantly white, the other urban and mostly African American. Crucial questions arose from his study of gender at these two schools. Why did boys tend to show less interest in and more defiance toward school? Why did girls significantly outperform boys at both schools? Why did people at the schools still describe boys as especially "smart"? Morris examines these questions and, in the process, illuminates connections of gender to race, class, and place. This book is not simply about the educational troubles of boys, but the troubled and complex experience of gender in school. It reveals how particular race, class, and geographical experiences shape masculinity and femininity in ways that affect academic performance. His findings add a new perspective to the "gender gap" in achievement.

The Human Body - The Facts Book for Future Doctors - Biology Books for Kids Revised Edition Children's Biology Books... The Human Body - The Facts Book for Future Doctors - Biology Books for Kids Revised Edition Children's Biology Books (Hardcover)
Baby Professor
R649 R579 Discovery Miles 5 790 Save R70 (11%) Ships in 10 - 15 working days
Biomedical Visualisation - Volume 10 (Hardcover, 1st ed. 2021): Paul M Rea Biomedical Visualisation - Volume 10 (Hardcover, 1st ed. 2021)
Paul M Rea
R4,615 Discovery Miles 46 150 Ships in 10 - 15 working days

This edited book explores the use of technology to enable us to visualise the life sciences in a more meaningful and engaging way. It will enable those interested in visualisation techniques to gain a better understanding of the applications that can be used in visualisation, imaging and analysis, education, engagement and training. The reader will also be able to learn about the use of visualisation techniques and technologies for the historical and forensic settings. The reader will be able to explore the utilisation of technologies from a number of fields to enable an engaging and meaningful visual representation of the biomedical sciences. The chapters presented in this volume cover such a diverse range of topics, with something for everyone. We present here chapters on technology enhanced learning in neuroanatomy; 3D printing and surgical planning; changes in higher education utilising technology, decolonising the curriculum and visual representations of the human body in education. We also showcase how not to use protective personal equipment inspired by the pandemic; anatomical and historical visualisation of obstetrics and gynaecology; 3D modelling of carpal bones and augmented reality for arachnid phobias for public engagement. In addition, we also present face modelling for surgical education in a multidisciplinary setting, military medical museum 3D digitising of historical pathology specimens and finally computational fluid dynamics.

Tell Me About: The Human Body (Hardcover): Emily Dodd Tell Me About: The Human Body (Hardcover)
Emily Dodd; Illustrated by Chorkung n/a
R296 R260 Discovery Miles 2 600 Save R36 (12%) Ships in 12 - 19 working days

Making big science topics just the right size for little readers as we explore the human body. Did you know that your body is two-thirds water? Or that it takes two days for food to go right through your body? The human body is pretty amazing, and we'd like to tell you why... So sit back, and let expert scientist and CBeebies writer Emily Dodd tell you all about the human body. With bite-sized text, facts to make you say 'WOW', and easy-to-understand explanations, big science topics are now just the right size for readers 4 years plus. Brilliantly illustrated by Chorkung, this is the perfect little book for readers who are just discovering all the AMAZING STUFF in the world around them.

Hypoxia - Into the Next Millennium (Hardcover): Robert C. Roach, Etc Hypoxia - Into the Next Millennium (Hardcover)
Robert C. Roach, Etc
R2,685 Discovery Miles 26 850 Ships in 12 - 19 working days

Hypoxia is a constant threat throughout life. International experts from many different fields, including clinicians, clinical researchers, and basic scientists, have contributed to this volume, presenting state-of-the-art information regarding normal and abnormal (pathophysiological) responses to hypoxia. The topics covered include visitors to high altitude, the latest developments on high-altitude cerebral and pulmonary edema, the brain in hypoxia, high-altitude headache, and similarities between ischemic and hypoxic injury to the brain. In addition topics are covered such as blood-brain barrier in hypoxia, hypoxia interactions with vascular growth, and how humans adjust to extreme hypoxia.

Photographic Atlas of Anatomy (Paperback, Ninth, International Edition): Johannes W. Rohen, Chihiro Yokochi, Elke Lutjen-Drecoll Photographic Atlas of Anatomy (Paperback, Ninth, International Edition)
Johannes W. Rohen, Chihiro Yokochi, Elke Lutjen-Drecoll
R2,152 Discovery Miles 21 520 Ships in 12 - 19 working days

Lippincott (R) Connect Featured Title Purchase of the new print edition of this Lippincott (R) Connect title includes access to the digital version of the book, plus related materials such as videos and multiple-choice Q&A and self-assessments. Photographic Atlas of Anatomy features outstanding full-color photographs of actual cadaver dissections, with accompanying schematic drawings and diagnostic images, to help students develop an unparalleled mastery of human anatomy with ease. Depicting anatomic structures more realistically than illustrations in traditional atlases, this proven resource shows students exactly what they will see in the dissection lab. Chapters are organized by region in the order of a typical dissection, with each chapter presenting regional anatomical structures in a systematic manner. This updated 9th edition includes revised content throughout and features additional cadaver dissection photos, medical imaging, and clinical illustrations, as well as a new appendix with learning resources that strengthen students' understanding of the vascular, lymphatic, muscular, and nervous systems. UPDATED! Chapters organized by region guide you through the order of a typical dissection. NEW! Appendix with learning resources reinforces your understanding of the vascular, lymphatic, muscular, and nervous systems. More than 1,200 full-color dissection photos, medical imaging, and clinical illustrations -all new or updated- depict key anatomical distinctions and functional connections as seen in the dissection lab. Authentic photographic reproduction of colors, structures, and spatial dimensions familiarize you with the human anatomy as seen in the dissection lab and on the operating table. Functional connections between single organs, the surrounding tissue, and organ systems are clarified to help you prepare for the dissection lab and practical exams. Dissections illustrate the regional anatomy in layers "from the outside in" to prepare you for the lab and operating room. Clinical comments strengthen your understanding and clinical readiness. Lippincott (R) Connect features: Full access to the digital version of the book with the ability to highlight and take notes on key passages for a more personal, efficient study experience. Carefully curated resources, such as interactive diagrams, audio and video tutorials, and self-assessment, all designed to facilitate further comprehension. Lippincott (R) Connect also allows users to create Study Collections to further personalize the study experience. With Study Collections you can: Pool content from books across your entire library into self-created Study Collections based on discipline, procedure, organ, concept or other topics. Display related text passages, video clips and self-assessment questions from each book (if available) for efficient absorption of material. Annotate and highlight key content for easy access later. Navigate seamlessly between book chapters, sections, self-assessments, notes and highlights in a single view/page.

Human Anatomy & Physiology Laboratory Manual, Fetal Pig Version, Global Edition (Paperback, 13th edition): Elaine Marieb, Lori... Human Anatomy & Physiology Laboratory Manual, Fetal Pig Version, Global Edition (Paperback, 13th edition)
Elaine Marieb, Lori Smith
R2,096 Discovery Miles 20 960 Ships in 12 - 19 working days

For the two-semester A&P laboratory course. Help manage time and improve learning inside and outside of the lab The #1 best-selling Human Anatomy & Physiology Laboratory Manual helps students and instructors manage time inside and outside of the A&P lab classroom and works hand-in-hand with Mastering A&P, the leading online homework and learning program for A&P. The 13th Edition features dozens of new, full-color figures and photos in the review sheets, as well as revamped clinical application questions and critical thinking questions that reinforce the most important concepts from lab. Encourage students to prepare for lab by assigning recommended Mastering A&P activities for each lab exercise, including 18 pre-lab videos (8 are new to this edition), Building Vocabulary Coaching Activities, exercise review sheet assessment questions, art labeling activities, mobile-ready Practice Anatomy Lab (TM) 3.1 with customizable flashcards, and more. Thousands of assignment options in the Item Library are closely correlated with the print edition of the manual, making it easier than ever to create homework assignments that are aligned with your lab activities. Continuing to set the standard for the 2-semester A&P laboratory course, the lab manual complies with the illustration and presentation style of the best-selling Marieb/Hoehn Human Anatomy & Physiology text, but can accompany any A&P textbook. New customization options are available through Pearson Collections, as well as three conventional versions: Main (12th Edition), Cat (13th Edition), and Fetal Pig (13th Edition). Also available with Mastering A&P Mastering (TM) is the teaching and learning platform that empowers you to reach every student. By combining trusted author content with digital tools developed to engage students and emulate the office-hour experience, Mastering personalizes learning and improves results for each student. Mastering A&P assignments support interactive features in the lab manual, including pre-lab video coaching activities, bone, muscle, and dissection videos, Dynamic Study Modules, Get Ready for A&P, plus a variety of Art Labeling Questions, Clinical Application Questions, and more. Note: You are purchasing a standalone product; Mastering A&P does not come packaged with this content. Students, if interested in purchasing this title with Mastering A&P, ask your instructor for the correct package ISBN and Course ID. Instructors, contact your Pearson representative for more information. If you would like to purchase both the physical text and Mastering A&P, search for: 0134767322 / 9780134767321 Human Anatomy & Physiology Laboratory Manual, Fetal Pig Version Plus MasteringA&P with Pearson eText -- Access Card Package, 13/e 0134763246 / 9780134763248 MasteringA&P with Pearson eText -- ValuePack Access Card -- for Human Anatomy & Physiology Laboratory Manuals 0134806360 / 9780134806365 Human Anatomy & Physiology Lab Manual, Fetal Pig Version

Human Paleoneurology (Hardcover, 2015 ed.): Emiliano Bruner Human Paleoneurology (Hardcover, 2015 ed.)
Emiliano Bruner
R4,513 R3,638 Discovery Miles 36 380 Save R875 (19%) Ships in 12 - 19 working days

The book presents an integrative review of paleoneurology, the study of endocranial morphology in fossil species. The main focus is on showing how computed methods can be used to support advances in evolutionary neuroanatomy, paleoanthropology and archaeology and how they have contributed to creating a completely new perspective in cognitive neuroscience. Moreover, thanks to its multidisciplinary approach, the book addresses students and researchers approaching human paleoneurology from different angles and for different purposes, such as biologists, physicians, anthropologists, archaeologists and computer scientists. The individual chapters, written by international experts, represent authoritative reviews of the most important topics in the field. All the concepts are presented in an easy-to-understand style, making them accessible to university students, newcomers and also to anyone interested in understanding how methods like biomedical imaging, digital anatomy and computed and multivariate morphometrics can be used for analyzing ontogenetic and phylogenetic changes according to the principles of functional morphology, morphological integration and modularity.

Neuroendocrine Clocks and Calendars (Hardcover, 1st ed. 2020): Francis J. P. Ebling, Hugh D. Piggins Neuroendocrine Clocks and Calendars (Hardcover, 1st ed. 2020)
Francis J. P. Ebling, Hugh D. Piggins
R3,041 Discovery Miles 30 410 Ships in 10 - 15 working days

This book explores how daily and seasonal rhythmicity is generated, how these rhythms are synchronised by our environment, and how they regulate the neuroendocrine systems that impact our physiology and behaviour. The constraints of surviving in a seasonal environment have shaped human evolution and migration, have shaped our societies and cultures, and continue to influence our everyday lives, health and wellbeing. Identifying the mechanisms whereby seasonal rhythmicity is generated and regulates the brain and body is not only important for understanding the natural world and relevant to animal production, it also offers many insights into the human condition. Each chapter is written by an international expert in the field of chronobiology. A historical perspective on how research into photoperiodism and rhythmicity progressed is initially provided, but the main focus of this book is on the remarkable studies in the last few decades that have unravelled the molecular and cellular machinery underpinning circadian and circannual timing. Topics covered include the role of melatonin in communicating seasonal information to the brain and pituitary gland, the neuroanatomical pathways in mammals, birds and fish by which changes in photoperiod reach the hypothalamus, the role of glial cells (tanycytes) and thyroid hormone in seasonal rhythmicity, neuroplasticity across seasons, effects of changing day length on mood, regulation of "clock" gene expression, and the role of the suprachiasmatic nucleus. This book will appeal to all students and researchers who wish to learn about current and past research on daily and seasonal rhythmicity. This is the tenth volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series (Volumes 1-7 published by Wiley) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.

Andreas Vesalius - The Making, the Madman, and the Myth (Hardcover): Stephen N. Joffe Andreas Vesalius - The Making, the Madman, and the Myth (Hardcover)
Stephen N. Joffe
R759 Discovery Miles 7 590 Ships in 12 - 19 working days

Andreas Vesalius 1514-1564 By Stephen N. Joffe, M.D. Vesalius was the foremost pioneer of modern anatomy. Born in Brussels, he came from a family of physicians. Educated in Louvain, he studied medicine in Montpelier and Paris, returning to Louvain to teach anatomy. In 1535 he went to France to be an army surgeon to King Charles V and two years later became a professor of anatomy in Padua, Italy. Subsequently he became a physician to the court of Philip II of Spain. On a pilgrimage to Jerusalem, he received a call to return to Padua to occupy chair of Fallopius. In a storm leading to a shipwreck and subsequent death on the Isle of Zante, Vesalius was buried there in an unmarked grave in 1564. This marked the end of the 'prince of anatomy.' Vesalius' book De Humani Corporus Fabrica published in Basel in 1543, contributes one of the greatest treasures of western civilization and culture. With its companion volume the Epitome, began the modern observational science and research.

Biomedical Tissue Culture Handbook (Hardcover): Hugh Waddell Biomedical Tissue Culture Handbook (Hardcover)
Hugh Waddell
R2,264 Discovery Miles 22 640 Ships in 12 - 19 working days
The Anatomical Male Muscular System Anatomical Chart (Wallchart, 2nd edition): Anatomical Chart Company The Anatomical Male Muscular System Anatomical Chart (Wallchart, 2nd edition)
Anatomical Chart Company
R663 R599 Discovery Miles 5 990 Save R64 (10%) Ships in 12 - 19 working days

The Anatomical Male Muscular System, Second Edition is a modern update of the bestselling, classic The Muscular System chart dating back to 1947. The illustrations are vividly colored and finely detailed, and structures are clearly labeled. The two large central illustrations show anterior and posterior views of the anatomical male muscular system, and four smaller inset illustrations show: Right Half of Diaphragm Muscles of Right Hand (Palmar View) Muscles of Posterior Abdominal Wall Muscles of the Right Foot (Plantar View) 20" x 26" heavy paper laminated with grommets at top corners

Functional Brain-Heart Interplay - From Physiology to Advanced Methodology of Signal Processing and Modeling (Hardcover, 1st... Functional Brain-Heart Interplay - From Physiology to Advanced Methodology of Signal Processing and Modeling (Hardcover, 1st ed. 2021)
Vincenzo Catrambone, Gaetano Valenza
R3,973 Discovery Miles 39 730 Ships in 12 - 19 working days

This monograph offers a cross-system exchange and cross-modality investigation into brain-heart interplay. Brain-Heart Interplay (BHI) is a highly interdisciplinary scientific topic, which spreads from the physiology of the Central/Autonomous Nervous Systems, especially Central Autonomic Network, to advanced signal processing and modeling for its activity quantification. Motivated by clinical evidence and supported by recent findings in neurophysiology, this monograph first explores the definition of basic Brain-Heart Interplay quantifiers, and then moves onto advanced methods for the assessment of health and disease states. Non-invasive use of brain monitoring techniques, including electroencephalogram and function Magnetic Resonance Imaging, will be described together with heartbeat dynamics monitoring through pulseoximeter and ECG signals. The audience of this book comprises especially of biomedical engineers and medical doctors with expertise in statistics and/or signal processing. Researchers in the fields of cardiology, neurology, psychiatry, and neuroscience in general may be interested as well.

Neuroanatomy of Neuroendocrine Systems (Hardcover, 1st ed. 2021): Valery Grinevich, Arpad Dobolyi Neuroanatomy of Neuroendocrine Systems (Hardcover, 1st ed. 2021)
Valery Grinevich, Arpad Dobolyi
R6,747 Discovery Miles 67 470 Ships in 10 - 15 working days

In this book, experts in the field provide comprehensive descriptions of the neuroanatomy of the hypothalamic neuroendocrine systems. The book begins with an extensive discussion on the structural components of the neuroendocrine systems. The reader will be introduced to the anatomy and biology of the hypothalamus and the pituitary. The human hypothalamus is presented in particular detail using state-of-the-art imaging techniques. In the next section, the neuroanatomy of traditional hypothalamo-hypophyseal systems is highlighted, with chapters describing magnocellular neuroendocrine cells and discussing the respective types of hypothalamic neurons that regulate various pituitary hormones. Following this detailed structural and anatomical description of the neuroendocrine system, the book's final section focuses on the hypothalamic control of neuroendocrine functions. This includes the control of circadian rhythm, metabolism and appetite via specific peptidergic circuits. This book provides essential information on the neuroanatomy and control of neuroendocrine systems, addresses cutting-edge research questions posed by recent advances in the development of potent neuroanatomical tools, and highlights the latest technologies used in neuroendocrinology research, making it a valuable reference guide for students, trainees and established researchers alike. This is the twelfth volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series, which aims to illustrate the highest standards and to encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.

The Everyday Physics of Hearing and Vision (Hardcover): Benjamin De Mayo The Everyday Physics of Hearing and Vision (Hardcover)
Benjamin De Mayo
R3,230 Discovery Miles 32 300 Ships in 10 - 15 working days

Humans receive the vast majority of sensory perception through the eyes and ears. This non-technical book examines the everyday physics behind hearing and vision to help readers understand more about themselves and their physical environment. It begins wit

Essentials in Hip and Ankle (Hardcover): Carlos Suarez-Ahedo, Anell Olivos-Meza, Arie M. Rijke Essentials in Hip and Ankle (Hardcover)
Carlos Suarez-Ahedo, Anell Olivos-Meza, Arie M. Rijke
R3,482 Discovery Miles 34 820 Ships in 10 - 15 working days
Anatomy Terminology Reference (Fold-out book or chart): Kate McPike Anatomy Terminology Reference (Fold-out book or chart)
Kate McPike
R248 Discovery Miles 2 480 Ships in 12 - 19 working days

What is the central sulcus within the brain? What do sebaceous glands secrete? These questions as well as many more are answered through the com-prehensive lists of anatomical terms and their defini-tions found within our latest 6 page study guide. The guide s easy-to-use format includes sections on each area of the human body and its accompanying terms; every word list is alphabetized so that users can find what they need quickly. Additionally, the guide is a great companion to our Anatomy QuickStudy(r) guide. Any medical student, doctor, or nurse should have this handy reference tool in his or her bookshelf

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Drosophila - Methods and Protocols (Hardcover, 2nd ed. 2016): Christian Dahmann Drosophila - Methods and Protocols (Hardcover, 2nd ed. 2016)
Christian Dahmann
R4,124 Discovery Miles 41 240 Ships in 12 - 19 working days

This second edition volume expands on the previous edition by presenting updated protocols for several of the techniques described in the first edition of Drosophila: Methods and Protocols and current methods that cover recent breakthroughs in Drosophila research. The book begins with a description of FlyBase--a database of genes and genomes--followed by the presentation of systems for versatile gene expression in the fly. The first few chapters in this book detail gene knockdown and editing, including CRISPR-Cas9 and protein knockdown. The next few chapters are devoted to methods describing live imaging of different tissues and organs, followed by chapters on how to quantify image data and how to probe tissue mechanics by laser ablation. The next two chapters provide methods for analyzing transcription followed by protocols to study growth, metabolism, ageing, and behavior in Drosophila. This volume concludes with chapters on electrophysiological recordings and methods to establish cell lines. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Drosophila: Methods and Protocols, Second Edition is a valuable source of hands-on protocols and reviews for molecular, cell, and developmental biologists using Drosophila as model systems in their work.

Guide to Dissection of the Human Body (Hardcover): F.P. Lisowski Guide to Dissection of the Human Body (Hardcover)
F.P. Lisowski
R1,382 Discovery Miles 13 820 Ships in 12 - 19 working days

This manual is intended to guide and facilitate human anatomical dissections. It is flexible enough for use in long as well as short courses. It can be particularly useful as a link with real anatomy when used together with computerised-anatomy programs, or where students do not dissect but merely look at atlases, prosections and models. There is an introduction for each anatomical region; and for each section to be dissected there is an overview, a dissection schedule which guides the student through a set of instructions, a summary and a list of objectives that are clinically important. The terminology used is the latest. The manual is suitable for medical and dental students. It is also of value for advanced knowledge of anatomy for surgery and in relation to the interpretation of normal anatomy in non-invasive imaging of anatomy for clinical diagnosis, surgical practice on cadaveric material, and in discussions about clinical problems.

RNA Processing - Disease and Genome-wide Probing (Hardcover, 1st ed. 2016): Gene W. Yeo RNA Processing - Disease and Genome-wide Probing (Hardcover, 1st ed. 2016)
Gene W. Yeo
R5,131 Discovery Miles 51 310 Ships in 12 - 19 working days

Ribonucleic acid (RNA) binding proteins currently number in the thousands and defects in their function are at the heart of diseases such as cancer and neurodegeneration. RNA binding proteins have become implicated in the intricate control of surprisingly diverse biological settings, such as circadian rhythm, stem cell self-renewal, oncogenesis and germ cell development. This book surveys a range of genome-wide and systems approaches to studying RNA binding proteins, the importance of RNA binding proteins in development, cancer and circadian rhythm.

Cellular and Molecular Control of Neuronal Migration (Hardcover, 2014 ed.): Laurent Nguyen, Simon Hippenmeyer Cellular and Molecular Control of Neuronal Migration (Hardcover, 2014 ed.)
Laurent Nguyen, Simon Hippenmeyer
R5,432 R5,076 Discovery Miles 50 760 Save R356 (7%) Ships in 12 - 19 working days

Cellular and Molecular Control of Neuronal Migration provides an up-to-date collection of reviews on the molecular and cellular principles of neuronal migration in the mammalian brain. Over the last decades a rich catalogue of signaling molecules controlling neuronal migration has been compiled, and within this book an international panel of experts provides up-to-date discussions of the state of knowledge how these distinct signaling pathways regulate various aspects of neuronal migration. This book introduces the reader to the latest discoveries and concepts of neuronal migration enabled through the application of most sophisticated methods and cutting edge experimental approaches. Cellular and Molecular Control of Neuronal Migration also provides an update on the underlying cellular and molecular basis of neurodevelopmental migration disorders in human patients for all interested neuroscientists and clinicians.

Learning the Brainstem (Hardcover): Edison K Miyawaki Learning the Brainstem (Hardcover)
Edison K Miyawaki
R758 R665 Discovery Miles 6 650 Save R93 (12%) Ships in 10 - 15 working days
Resistance to Aromatase Inhibitors in Breast Cancer (Hardcover, 2015 ed.): Alexey Larionov Resistance to Aromatase Inhibitors in Breast Cancer (Hardcover, 2015 ed.)
Alexey Larionov
R4,565 R3,689 Discovery Miles 36 890 Save R876 (19%) Ships in 12 - 19 working days

Aromatase Inhibitors (AIs) treat postmenopausal estrogen receptor positive tumours, which constitute the majority of breast cancer patients. This comprehensive volume brings together the current knowledge from different relevant areas, including molecular mechanisms and translational aspects of drug resistance in AIs. Topics covered include research, experimental , and clinical data specifically focused on AI resistance in breast cancer. The volume will include three sections. The first section covers general knowledge about aromatase inhibitors, including regulation of aromatase genes, and structure and function of aromatase protein. The second section provides the detailed mechanisms of resistance to AIs, while the third section explores prediction of resistance and potential strategies to overcome resistance. Breast cancer is the most common female cancer and AIs significantly improve treatments outcomes compatibly to previously used endocrine treatments. However 10-15% of post-operative patients develop a relapse during adjuvant treatment with AIs; about 25-50% of the patients do not respond to AIs in neo-adjuvant or metastatic setting, and the majority of metastatic patients who initially respond develop resistance within 3 years. There is an important need to understand these mechanisms of resistance in order to develop methods of preventing or overcoming the resistance to AIs, which will ensure a more successful outcome in treating breast cancer.

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