This invaluable book provides the first description of the diverse and fascinating functions of heme in life processes for a broad audience. It begins with an introduction to the intricate chemical properties of heme and the history of early observations of human diseases associated with heme. It then proceeds to describe the versatile roles of heme in controlling diverse molecular and cellular processes germane to human life and disease processes. Finally, an up-to-date review of human diseases associated with heme synthesis and application of heme synthesis in photodynamic therapy in cancer treatment is presented.Heme biology is unified and logical in presentation. It is well suited for students and professionals in life sciences who wish to comprehend the fascinating biology of heme and its usefulness in health and diseases. It may also be used as a reference book for advanced readers and researchers who are interested in heme biology. The explanations in the book are detailed enough to capture the interest of the curious reader, and complete enough to provide the necessary information for researchers to have an in-depth molecular understanding of heme biology and further their studies in this fascinating realm.

Thoroughly revised and updated to reflect key advances in behavioral neurology, "Neurobehavioral Anatomy, Third Edition" is a clinically based account of the neuroanatomy of human behavior centered on a consideration of behavioral dysfunction caused by disorders of the brain. A concise introduction to brain-behavior relationships that enhances patient care and assists medical students, the book also serves as a handy reference to researchers, neuroscientists, psychiatrists, and geriatricians.

The book outlines how cognitive and emotional functions are represented and organized in the brain to produce the behaviors regarded as uniquely human. It reviews the effects of focal and diffuse brain lesions, and from this analysis a conception of the normal operations of the healthy brain emerges. Christopher M. Filley integrates data and material from different disciplines to create a concise and accessible synthesis that informs the clinical understanding of brain-behavior relationships. Clinically practical and theoretically stimulating, the book is an invaluable resource for those involved in the clinical care and study of people with neurobehavioral disorders.

Including a useful glossary and extensive references guiding users to further research, the third edition will be of significance to medical students, residents, fellows, practicing physicians, and the general reader interested in neurology.

Applied Anatomy for the FRCA covers the anatomical knowledge that trainee anaesthetists who are revising for the Primary and Final FRCA exams will need. The topics covered are derived from the FRCA curriculum and include the most up-to-date version of past exam questions, in order to ensure targeted and successful exam revision. The content, illustrations and overall layout of this book ensure that common gaps in anatomical knowledge encountered by FRCA trainees are included. This reference is divided into sections pertaining to anatomical regions: head and neck, thorax, abdomen, spine, and the upper and lower limbs. The topics of importance to anaesthetists are presented under 'structures', 'circulation' and 'nervous system' (with relevance to regional anaesthesia). Each topic is extensively researched and presented in a simple format for maximum retention. This book makes learning and remembering applied anatomy as straightforward as possible. Applied Anatomy for the FRCA supplements the knowledge required by trainee anaesthetists appearing for the FRCA exams. Clinical educators will also find it useful in teaching. It serves as a practical reference for anatomical knowledge at any point in an anaesthetist's career. About the Editors Dr Bobby Krishnachetty has been a Consultant Anaesthetist at Southend University Hospital since 2010 and a college tutor for six years. She completed her diploma in medical education and is the author of The Final FRCA Structured Oral Examination: A Complete Guide. She is also the organiser of the regional teaching for Core trainees in the East of England school of anaesthesia, as well as Founder of the 'Southend Viva Club' Primary and Final FRCA SOE revision courses for more than nine years, and Cofounder of MRCS OSCE webinars. Mr Abdul Syed has been a Consultant Surgeon at Southend University Hospital since 2015. He is Lead for postgraduate teaching of surgical trainees, Cofounder of MRCS OSCE webinars and conducts Core surgical trainee interview skills courses. Mr Syed is also an Assessor for medical school interviews and an active participant in QI projects and research.

Frédéric Delavier’s artwork has amazed readers for years, with over two million people turning to his books—including the best-selling Strength Training Anatomy—to learn how muscles perform and affect the body during exercise. Now he brings his work to life again with Strength Training Anatomy for Athletes. With over 600 full-color photos and 300 anatomical illustrations, you’ll be taken inside 46 exercises specifically selected for the demands of 43 sports and activities. You’ll see how muscles interact with surrounding joints and skeletal structures and how variations and sequencing can isolate specific muscles for more effective and efficient training. Strength Training Anatomy for Athletes guides you in analyzing the needs of your sport and identifying the most effective exercises for your body type, physical conditioning, and performance goals. You’ll enhance your strengths and minimize your weaknesses with programs for 43 sports and activities, including these: Archery Basketball Baseball and softball Combat sports Cycling Football Golf Rugby Soccer Swimming and diving Tennis Volleyball Featuring exercises for warm-up, recovery, and injury prevention, Strength Training Anatomy for Athletes is a comprehensive, yet practical, guide to optimizing athletic performance.

The way you perceive the world, plan, make decisions and communicate your thoughts and feelings depends on the function and hierarchical arrangement of cortical modules. The ability to both provide adaptive responses to our ever-changing environment and to pursue a useful role in society is the most important problem faced by present day neuroscientists. In essence, the workings of cortical modules define the nature of our soul, making each of us who we are. This book provides a breath-taking view of different perspectives by world renowned authorities as to the workings of these cortical modules both in the normal state and in mental disorders.

Netter's Integrated Musculoskeletal System is an innovative new text that brings together basic science material from several domains, providing a solid foundation prior to delving into topics of increasing complexity and clinical importance -all highlighted by superb Netter illustrations throughout. Initial chapters give a general overview of the human body, while the remaining chapters examine all facets of the musculoskeletal system, the injuries that affect it at the macroscopic and microscopic levels, and the process of development. As the scientific content becomes more complex, the clinical correlations become more specific. This progressively constructed narrative guides readers efficiently and effectively through the intricacies of the musculoskeletal system in a way that is easy to understand and remember-all in a single, time-saving resource for busy students. Takes an integrated approach including gross anatomy, physiology, biochemistry, neuroscience, histology, and other relevant sciences to better help readers understand the musculoskeletal system. Presents essential content in an easy-to-understand manner, puts it in context, and then elaborates on it with more detail-making connections between content areas and reducing the need for multiple study resources. Features clinical correlations boxes throughout; includes an appendix of commonly-used eponyms to help readers communicate across disciplines and an appendix of Latin/Greek/Arabic roots for anatomical terms. Designed to be used effectively in longitudinally-designed, integrated curricula-for a wide range of health-science students-with carefully organized, concise reading assignments and discrete areas of study for each lesson. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

The Sobotta Coloring Book - for understanding and learning anatomy The Sobotta Coloring Book offers another excellent way to study anatomy, perfectly suited to all those who are looking for an alternative to learning from textbooks. Dealing with the most important subjects in anatomy, the texts and the simple drawings designed to be colored-in help to understand and revise the most important aspects of human anatomy. This turns the book into something special: the pictures show the basic anatomical details and the accompanying texts explain the most important aspects of the structures. By actively interacting with the book through coloring-in, the content becomes deeply ingrained in the memory. The Sobotta Coloring Book provides: basic anatomical details in over 100 sections, using pictures and text concise accompanying texts for each picture, highlighting important details clinical references, pointing out their practical relevance sketches of sectional planes and perspectives which help with orientation English - Latin Nomenclature

This repackaged edition of this best-selling guide to anatomy in art that will help artists of all levels to improve their life-drawing skills. Unlock your inner artist and discover how to draw the human body in this beautifully-illustrated art book by celebrated artist and teacher, Sarah Simblet. Whether you're looking to develop a new skill this New Year, or develop your drawing skills even further, this visually-striking guide offers a fresh approach to drawing the human body. Dive straight in to discover: -Over 250 specially-commissioned photographs and drawings -Covers each part of the human body from head to toe -10 masterclasses demonstrate how famous artists have depicted the human body -Practical advice and top-tips on life drawing Combining stunning photographs of models with historical and contemporary works of art and her own dynamic life drawing, Sarah will take you on a journey inside the human body to map its skeleton, muscle groups and body systems. Bring your artwork to life in the most dynamic way possible, with detailed line drawings superimposed over photographs to reveal the links between the body's appearance and it's construction. Featuring inspirational master classes on world-famous artworks, from Michelangelo to Hans Holbein, Ingres to Degas and more, discover how artists have depicted the human body over centuries. Each master class features a photograph of a model holding the same pose as in the painting, to highlight key details of anatomy and show how the artist has interpreted them. Understanding anatomy is the foundation to understanding the human body successfully. As well as being the perfect reference, Anatomy for the Artist will inspire you to find a model, reach for your pencil and start drawing! Let DK plant the seed of curiosity and watch as it develops into a life-long love of art, anatomy and more. A must-have volume for artists of all levels who wish to tackle life drawing, or those interested in human anatomy, whether as a gift or self-purchase.

Comprehensive book on mitral stenosis not only compiles the existing published knowledge and literature about mitral stenosis in a succinct manner but also has input from experts having years of experience in this field. It will serve as an authentic reference and a ready reckoner for cardiology fellows, practicing cardiologists, academics and researchers

Explore the science behind over 50 pilates exercises to master each movement with confidence and control. DK brings you a ground-breaking health book that will help you revitalise your workouts and perfect your Pilates practice, by understanding the muscle action, breathwork and techniques required, every step of the way. Did you know that performing Pilates can strengthen your core, improve flexibility and posture, and help to reduce stress and anxiety at the same time? Backed by scientific research, learn how Pilates exercises benefit every system in the body. Science of Pilates reveals the facts with annotated artworks that show the mechanics, the angles, how your blood flow and respiration are affected, the key muscle and joint actions working below the surface of each exercise, safe alignment, and much more! Go on a journey of self-discovery to explore: - Specially commissioned CGI artworks depict all the main Pilates exercises with variations that add or reduce challenge. - Artworks detail the mechanics of each exercise, correct body posture, the muscles involved and how they engage to perform movements. - Illustrations featuring colour-coding to highlight how the muscles, ligaments, and joints engage, stretch, and relax to perform each exercise. - Pilates programmes tailored to different abilities and aims. - Suggested practices with a progressive increase in challenge over weeks and months. - Easy-to-follow infographics help explain the hard science behind why Pilates training is so effective and what beneficial physical adaptations it can bring. Set out to unearth the facts behind the pseudo-science fads, The Science of Pilates is an approachable, entertaining and easy-to read fitness guide for those seeking self-development backed up by solid scientific evidence. The popular question and answer format brings an immediacy to the information provided, and the highly visually illustrations truly bring the science to life in a contemporary and accessible way. At DK, we believe in the power of discovery. So why stop there? If you like Science of Pilates, then why not try Science of Yoga to help you better understand yoga anatomy in order to perfect your practice and poses, or Science of Strength Training to support you in your journey to build you strongest body. Complete the collection today!

This manual guides the student through an organised regional study of the human brain proceeding from caudal to rostal direction. Different parts of the brain are described both on a gross and light microscopic level. The important structures of each brain region are emphasized not only in the text but also in the accompanying micrographs and line drawings. Where appropriate, the text also describes the histological organisation of the brain. A series of CAT scan pictures has also been included as an exercise for the students to correlate their knowledge on brain with X-ray images. This manual would serve as a foundation for necessary and practical information for future clinical years.

Now in its fourteenth edition, this best-selling textbook has been honed over many years to provide a clear, straightforward introduction to the human body for students of nursing, allied health or biomedical and paramedical science. The book covers the core essentials of anatomy and physiology, including basic pathology and pathophysiology of important diseases and disorders. This new edition presents additional illustrations to enhance understanding of key concepts, including pathophysiology and diagnostics. Included for the first time is an introduction to surface anatomy, while other updating reflects current scientific knowledge and developments, including coronavirus. Enhanced learning features and an extensive online resource help you grasp all the important areas. Like millions of readers before you, you will treasure Ross & Wilson as a go-to resource that you will refer to time and again to support this critical aspect of your healthcare education. Clear and easy to read - suitable for students new to the area and anyone whose first language is not English Hundreds of stunning illustrations and images to make learning easy Helpful learning features such as Learning Outcomes boxes, colour coding and orientation icons to facilitate navigation Definitions of common prefixes, suffixes and roots, examples, glossary and an appendix of normal biological values Self-assessment activities in each chapter, including 'spot check' questions for each section and case studies with answers to develop understanding of key principles Accompanying website with animations, videos, audio-glossary and other self-assessment material Evolve Study Resources Online content offered with Ross & Wilson Anatomy and Physiology in Health and Illness 14th edition includes: New for this edition - a set of expert-narrated 3D videos summarizing key topics in the book, powered by Complete Anatomy: the world's most advanced 3D anatomy platform Over 120 animations clarifying underlying principles and make learning fun More than 1700 audio glossary entries Body Spectrum (c) online colouring and self-test software Self-assessment questions to help students test their knowledge

Prepare for a career as a leading respiratory therapist with the solid foundation in anatomy and physiology found in Des Jardins' best-selling CARDIOPULMONARY ANATOMY & PHYSIOLOGY: ESSENTIALS OF RESPIRATORY CARE, 7E. This extremely reader-friendly presentation delivers the most complete, accurate information about the structure and function of the respiratory system. Clear and concise coverage presents even complicated concepts in an understandable format using full-color design and proven learning features that guide you in applying what you've learned to your professional career. Thirteen new Clinical Connections add to the book's total 141 Clinical Connections that link chapter content to today's clinical setting and highlight actual situations that respiratory therapists encounter every day. These features also direct meaningful discussion and strengthen your critical-thinking skills.

Reveals an Emerging Avenue of Potential Treatments for a Host of Challenging Diseases and Disorders The H3 receptor is known to play a major role in a range of CNS disorders, including those affecting cognitive functions such as ADHD and Alzheimer's disease, as well as sleep disorders, obesity, epilepsy, schizophrenia, depression, and neurodegeneration. In light of dramatic advances in research at the molecular level, supported by impressive clinical studies, optimism remains high that an H3 receptor-related drug could hit the market soon. The Third Histamine Receptor: Selective Ligands as Potential Therapeutic Agents in CNS Disorders provides a thorough grounding in advances made over the last two decades. It brings together an elite group of 30 pioneering researchers. In writing about their own work, these scientists report on the cutting-edge investigations that are now being conducted across a variety of disciplines. This text is designed to aid researchers and inform those involved in the treatment and clinical aspects of a number of histamine-related diseases. Presents Several Disease-Specific Chapters Certainly, the most comprehensive and cutting-edge volume in the field, this text includes material drawn from groundbreaking research techniques and patent literature. Put together with great thought and passion, it is written to serve as a primary resource for anyone involved with or interested in the identification and localization of H3 receptors and the ligands being developed as therapeutic agents to treat a wide range of diseases including some that were once considered intractable.

Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur, new possibilities emerge for limiting the effects of aging on neural function. A single source reference is necessary to keep abreast of the recent advances and future directions of gerontology research. Brain Aging: Models, Methods, and Mechanisms offers a selective overview of the research in this rapidly expanding field. A valuable resource for new and established investigators of the aging brain, this volume reviews critical studies of brain aging in new animal models, as well as advances in brain imaging techniques that permit investigations in aging humans with increasingly higher resolution. Detailed discussions link the information from human and animal studies to illustrate a comprehensive picture of the mechanism of aging. Emphasizing normal brain aging rather than pathological degeneration, the text provides an understanding of fundamental age-related changes in the nervous system and hypothesis-driven research into their basis. The book includes critical analyses of the distinct methodological challenges inherent in investigating the aging nervous system. Contributions from distinguished leaders and pioneers in their respective fields address data and mechanisms, as well as models and methods that are key to the study of aging. Each chapter is extensively referenced and highlights experimental concerns that are magnified or unique to the aging brain. Outlining relevant methods and techniques, this book provides scientists, researchers, and clinicians with a broad understanding of the important progress and implications for the future of this significant field.

Disorders of the Autonomic Nervous System, the fifth volume in The Autonomic Nervous System book series, is a description of the disorders which give rise to autonomic failure and orthostatic hypotension. Each chapter is prepared by an international authority in the diagnosis and treatment of that disorder. The language and terminology are clear enough to promote understanding of the clinical problems and the underlying concepts of basic science. The most recent data, especially that derived from molecular biology, is included in the discussions of relevant diseases. Hence, the volume provides an unparalleled source of information about this area of medicine and will be helpful not just to practising clinicians but also to basic scientists researching in the field who need to familiarize themselves with the clinical problems.

This book is dedicated to those who died of malignant hyperthermia and to their families. It contains cases studies that would be helpful for anesthesiologists, surgeons, physiologists, molecular biologists, biophysicists, biochemists, pathologists, students, and post doctoral fellows.

The author of a number of acclaimed, best-selling surgical atlases has collaborated again with an award-winning artist to produce another invaluable surgical resource. This highly regarded team provide a master-class in the demonstration of surgically relevant anatomy. Masquelet has attained world-renown in particular for his innovative flaps for reconstructive plastic surgery of the limbs, in this book he displays his unrivalled knowledge of surgery of the trunk, head, and neck. Every point of entry in required surgical procedures is described, and every procedure is illustrated with a sequence of drawings, displayed as the surgeon would see them, together with anatomical cross-sections.

Anaesthesiologists regularly administer potent, and potentially toxic, drugs that profoundly interfere with fundamental physiological functions such as breathing, cardiac output, blood pressure, the protective reflexes and the perception of pain. Reviewing all aspects of human physiology, Physiology for Anaesthesiologists provides a working knowledge of physiological principles and their application to anaesthesia and intensive care. The text covers the various systems of the human body, from the central nervous system to the liver and kidneys. The reader gains an understanding not only of each system discussed, but also of how each of those physiological systems interact with each other. The section on pain, for example, explains how the body warns of dysfunction in one or more systems. In addition to covering the core material for professional examinations, some topics not usually dealt with in textbooks for anaesthetists are also covered, such as the impact of anaesthesia and surgery on the immune system. Written in a clear and concise style, the book supplies up-to-date information to trainees in anaesthesiology and related specialities preparing for professional examinations: both editors have a wealth of experience in these subjects. The book also helps established anaesthesiologists, and those in other related specialities, who want to keep up with recent developments in the field.

As one of the first cortical areas to be explored experimentally, the motor cortex continues to be the focus of intense research. Motor Cortex in Voluntary Movements: A Distributed System for Distributed Functions presents developments in motor cortex research, making it possible to understand and interpret neural activity and use it to reconstruct movements. Featuring viewpoints based on monkey and human studies, the book focuses on how neuronal activity changes during learning, discusses what the motor cortex encodes for, and covers the neuronal representations of voluntary movements and the mechanism of their generation during learning. Section 1 uses functional neuroanatomy and imaging studies to describe motor cortical function, and Section 2 provides an overview of studies about neural representations in the motor cortex. The third section concentrates on motor learning, and the final section highlights the reconstruction of movements using brain activity. Revealing many exciting applications of this rapidly expanding science, this book enhances our understanding of the generation of motor commands. It is an essential resource for neuroscientists interested in motor function, rehabilitation medicine practitioners, and biomedical engineers.

This reference compiles the most current technical and biological data available to survey the state-of-science in the care and management of patients with bronchopulmonary dysplasia, COPD, and other forms of lung disease-tracking the initiation and progression of processes that cause airway obstruction, the biologic and physiological abnormalities that characterize COPD, and the potential reversibility of the inflammatory response in COPD for improved patient diagnosis and treatment.

This is the loose-leaf version of Kinetic Anatomy, Fourth Edition, which offers students a less expensive, printed version of the text. Kinetic Anatomy, Fourth Edition With HKPropel Access, gives students a firm concept of musculoskeletal anatomy by systematically assembling each component of the human body. Layer by layer, readers will study bones, ligaments, joints, and muscles as well as the nerves and blood vessels that supply these muscles that are essential for movement.With full-color visual aids and activities that invite readers to apply their understanding of structural anatomy to their own lives, the fourth edition is ideally suited for students studying physical activity because it explores how the structural anatomy of the human body facilitates movement. Part I of the text introduces the basics of structural anatomy. It describes how bones, joints, muscles, nerves, and other essential anatomy work together to allow for fundamental movement. Part II details the anatomy of the upper extremity region, including the shoulder, elbow, forearm, wrist, and hand. Part III of the text explores the anatomy of the head, spinal column, thorax, and pelvis. These chapters include unique coverage not found in other anatomy texts, explaining how the brain, heart, and lungs-as the power centers of the nervous, cardiovascular, and respiratory systems-affect movement. Part IV discusses the anatomy of the lower extremity region: the hip, thigh, knee, lower leg, ankle, and foot. Parts II, III, and IV each end with a summary table that offers a quick reference for the components of the body region featured in that part. Kinetic Anatomy, Fourth Edition, contains nearly 400 photos, illustrations, and infographics to help readers visualize structural anatomy and engage with their coursework. Throughout the book, Hands On exercises instruct readers to physically identify anatomical structures on themselves or on a partner, and Focus On sidebars illustrate circumstances in everyday activity that relate to the specific anatomical structures in the text. Pop quizzes provide readers an opportunity to strengthen their clinical reasoning skills by asking them to identify the muscles shown in the accompanying photo. The fourth edition is further enhanced with the addition of new online learning tools -all of which can be assigned, and progress tracked, by instructors directly through HKPropel: Anatomy labeling and coloring sheets offer students nearly 100 interactive activities that test their knowledge of anatomical structures and function. Learning activities; true-false, multiple-choice, and fill-in-the-blank questions; and functional movement exercises ensure students have a firm grasp of key points from each chapter. Chapter quizzes (assessments) may also be assigned; these are automatically graded to test comprehension of critical concepts. Readers of Kinetic Anatomy, Fourth Edition, will learn what structures are involved in movement and how those structures should function, allowing them to identify problems and correct them to enhance physical activity. Anyone interested in just how their body functions during physical activity and how certain overuse or misuse can affect certain anatomical structures will benefit from this book. Note: A code for accessing HKPropel is included with all new print books.

Edited by an expert team of researchers and clinicians, The Epidermis in Wound Healing combines current information with the latest research results to provide a complete picture of the latest advances in the field. Presenting the newest findings, the book focuses on biological advances that improve knowledge and lead to new opportunities for research and clinical applications. Topics include quantifying repair in the epidermis, physical and chemical factors affecting repair, new approaches to understanding and treating wounds, and the role of gene action in the epidermis during wound repair. A unique feature is the inclusion of a critical evaluation of current clinical practices.