Written by an experienced and well-respected physician and professor, this new volume combines the entire previous four books, Ultrasonic Topographical and Pathotopographical Anatomy, and its three sequels, also available from Wiley-Scrivener, presenings the ultrasonic topographical and pathotopographical anatomy of the entire body, offering further detail into these important areas for use by medical professionals. This comprehensive and exhaustive medical atlas of topographic and pathotopographic human anatomy is a fundamental and practically important book designed for doctors of all specializations and students of medical schools. Here you can find almost everything that is connected with the topographic and pathotopographic human anatomy, including original graphs of logical structures of topographic anatomy and development of congenital abnormalities, topography of different areas in layers, pathotopography, computer and magnetic resonance imaging (MRI) of topographic and pathotopographic anatomy. You can also find here new theoretical and practical sections of topographic anatomy developed by the author himself which are published for the first time. They are practically important for mastering the technique of operative interventions and denying possibility of iatrogenic complications during operations. This important new volume will be valuable to physicians, junior physicians, medical residents, lecturers in medicine, and medical students alike, either as a textbook or as a reference. It is a must-have for any physician's library.

Aromatase Inhibitors (AIs) treat postmenopausal estrogen receptor positive tumours, which constitute the majority of breast cancer patients. This comprehensive volume brings together the current knowledge from different relevant areas, including molecular mechanisms and translational aspects of drug resistance in AIs. Topics covered include research, experimental , and clinical data specifically focused on AI resistance in breast cancer. The volume will include three sections. The first section covers general knowledge about aromatase inhibitors, including regulation of aromatase genes, and structure and function of aromatase protein. The second section provides the detailed mechanisms of resistance to AIs, while the third section explores prediction of resistance and potential strategies to overcome resistance. Breast cancer is the most common female cancer and AIs significantly improve treatments outcomes compatibly to previously used endocrine treatments. However 10-15% of post-operative patients develop a relapse during adjuvant treatment with AIs; about 25-50% of the patients do not respond to AIs in neo-adjuvant or metastatic setting, and the majority of metastatic patients who initially respond develop resistance within 3 years. There is an important need to understand these mechanisms of resistance in order to develop methods of preventing or overcoming the resistance to AIs, which will ensure a more successful outcome in treating breast cancer.

The mammalian hippocampus is a conserved region and probably one of the best-studied brain areas. However, the homologous regions in other vertebrates differ in the anatomical organization, but are still able to perform similar functions. In this special topic issue, international experts in evolutionary neuroscience discuss the homology of the hippocampus among fishes, amphibians, reptiles, birds, and mammals. The articles cover the history of hippocampal research, developmental patterns of gene expression in mammals, birds and reptiles, and the internal connectivity in adult birds and mammals. Furthermore it explores the role of the hippocampus in spatial navigation and memory, as well as its role in social cognition and in regulating the stress response. In addition to evolutionary neuroscientists, this publication is of special interest to all those studying the mammalian hippocampus, as it puts their structure of interest in a wider evolutionary context. It will also be relevant to behavioral ecologists and other behavioral biologists interested in navigation and memory across a range of species.

Winner of the Richard Asher Prize for a First Medical Textbook for Students Responding to current trends in anatomy curricula, this innovative new resource covers surface and radiological anatomy and cutaneous and muscular innervations as well as gross anatomy. Outstandingly realistic three-dimensional photographs and illustrations, plus a consistent chapter organization, summary tables, and other user-friendly features, enhance readers' mastery of essential information. It provides students with a unique resource for use before, during and after lab work, in preparation for examinations, and later on as a primer for clinical work. Get a clear understanding of surface, gross, and radiologic anatomy with a resource that's great for use before, during, and after lab work, in preparation for examinations, and later on as a primer for clinical work. Learn as intuitively as possible with large, full-page photos for effortless comprehension. No more confusion and peering at small, closely cropped pictures! Easily distinguish highlighted structures from the background in each dissection with the aid of digitally color-enhanced images. See structures the way they present in the anatomy lab with specially commissioned dissections, all done using freshly dissected cadavers prepared using low-alcohol fixative. Bridge the gap between gross anatomy and clinical practice with clinical correlations throughout. Master anatomy efficiently with one text covering all you need to know, from surface to radiologic anatomy, that's ideal for shortened anatomy courses. Review key structures quickly thanks to detailed dissection headings and unique icon navigation. Access the full text and self assessment questions at studentconsult.com. Get a clear understanding of the human body through surface, gross and radiologic anatomy all in one place.

This evidence-based guide is the first of its kind to outline the surgical and perioperative management of patients with anatomical anomalies and support clinical decision-making under these difficult circumstances. Presented in a simple, accessible format and organized by anatomical area, this book contains all the essential topics required by trainees and practitioners to assess the patient quickly, diagnose anatomic anomalies, determine the feasibility and safety of the planned surgical and anesthetic procedures, and arrange for advanced consults and care, if needed. Newer techniques for surgical and anesthetic management of patients with anatomic anomalies are presented to facilitate practitioners' development of their skills. Chapters include the latest ultrasound techniques and images, as well as case studies. Physicians, nurses, and trainees involved in the surgical, anesthetic, perioperative, or critical care of patients will find this guide to be their go-to resource in the OR, lab, or pain clinic.

High-yield and masterfully illustrated guide provides the definitive state-of-the-art text for learning this challenging subject. In the tradition of the highly praised first edition, Anatomy: An Essential Textbook, Second Edition by Anne M. Gilroy features noteworthy additions including radiographic representation of anatomical structures and illustrated clinical correlations. The introductory chapter lays a solid foundation with basic concepts and expanded coverage of the vascular and nervous systems. Each profusely illustrated regional unit includes an overview, comprehensive information on bones, muscles, and neurovasculature and clinical imaging followed by review questions with complete answers and explanations. Over 200 new images and 650 total show normal and pathologic anatomy and procedures Over 120 tables facilitate learning and include unique tables listing origin, insertion, innervation and action of muscles Online access to WinkingSkull.com with "labels-on, labels-off" for self-testing of images and interactive review questions and answers Clinical Correlation boxes provide detailed information on anatomic basis of clinical problems Development Correlation boxes highlight important embryologic and life cycle concepts related to anatomical structures New Clinical Imaging Basics sections address the practical applications of imaging modalities for specific anatomical regions Build your anatomy knowledge and confidence with this stellar text.

Both the number of pediatric surgeons using minimally invasive surgery (MIS) and the number of operations involving MIS are increasing. This atlas of anatomy and operative techniques provides a thorough outline of the procedures commonly used in laparoscopic and thoracoscopic pediatric surgery. Step-by-step operative photographs are accompanied by explanatory text, and line diagrams are used to highlight the important anatomy as seen endoscopically. Alternative techniques, instruments, and steps are described when appropriate, and attention is drawn to highlights and pitfalls. While each chapter includes some basic background on the condition in question, the focus is very much on the operative procedures. This atlas will be of special benefit to those establishing a laparoscopic practice as well as to those in training who wish to embark on MIS. It will also serve as a supplementary atlas of anatomy and surgical technique for younger surgeons and medical students.

This didactic book clearly and systematically describes the anatomical-surgical fundamentals of cranial neurosurgery, relating them to norm variants, imaging modalities and interdisciplinary aspects. All illustrations, hand drawn in ink by the first author, are simple and self-explanatory. The book reflects the first author's lifetime experience as an academic neurosurgeon and teacher, as well as the second author's theoretical and practical knowledge of neurosurgical subspecialties such as epilepsy surgery. In addition to its core audience in neurosurgery, it provides all connected disciplines, in particular neuroradiology, neurology, neuropathology, ENT surgery, maxillofacial surgery and eye surgery, with unique anatomical insights into the neurosurgeon's perspective.

The book presents an integrative review of paleoneurology, the study of endocranial morphology in fossil species. The main focus is on showing how computed methods can be used to support advances in evolutionary neuroanatomy, paleoanthropology and archaeology and how they have contributed to creating a completely new perspective in cognitive neuroscience. Moreover, thanks to its multidisciplinary approach, the book addresses students and researchers approaching human paleoneurology from different angles and for different purposes, such as biologists, physicians, anthropologists, archaeologists and computer scientists. The individual chapters, written by international experts, represent authoritative reviews of the most important topics in the field. All the concepts are presented in an easy-to-understand style, making them accessible to university students, newcomers and also to anyone interested in understanding how methods like biomedical imaging, digital anatomy and computed and multivariate morphometrics can be used for analyzing ontogenetic and phylogenetic changes according to the principles of functional morphology, morphological integration and modularity.

A single-volume resource for detailed coverage of the anatomy, function, and pathology of the cranial nerves with CT and MRI correlation

"Unique...provid es] clear, concise descriptions...the first of its kind to offer a detailed look at the imaging findings of each cranial nerve in both normal and pathological states.--Journal of Neurosurgery"

"This book reaches its objective. It must be part of the library of the neurological surgery student as a useful tool for understanding basic anatomy and physiology, as well as the most common pathologies and the basic neuroradiology of the cranial nerves. We strongly recommend it.-- World Neurosurgery"

"This book is of interest to everyone who aims a solid understanding of the cranial nerves. --Central European Neurosurgery"

This beautifully illustrated book combines a detailed exposition of the anatomy and function of the cranial nerves with practical coverage of clinical concepts for the assessment and differential diagnosis of cranial nerve dysfunction. An introductory chapter provides a brief overview of cranial nerve anatomy and function, skull base anatomy, classification of pathologies, and imaging approaches. Each of the twelve chapters that follow is devoted to in-depth coverage of a different cranial nerve. These chapters open with detailed discussion of the various functions of each nerve and normal anatomy. The authors then describe common lesions and present a series of cases that are complemented by CT images and MRIs to illustrate disease entities that result in cranial nerve dysfunction.

Features

• Concise descriptions in a bulleted outline format enable rapid reading and review
• Tables synthesize key information related to anatomy, function, pathology, and imaging
• More than 300 high-quality illustrations and state-of-the-art CT and MR images demonstrate important anatomic concepts and pathologic findings
• Pearls emphasize clinical information and key imaging findings for diagnosis and treatment
• Appendices include detailed information on brainstem anatomy, pupil and eye movement control, parasympathetic ganglia, and cranial nerve reflexes

This book is an indispensable reference for practicing physicians and trainees in neurosurgery, neurology, neuroradiology, radiology, and otolaryngology-head and neck surgery. It will also serve as a valuable resource for students seeking to gain a solid understanding of the anatomy, function, and pathology of the cranial nerves.

A concise and visual guide to clinically relevant anatomy for dentistry, Netter's Head and Neck Anatomy for Dentistry is an effective text for class and exam preparation, as well as a quick review in professional practice. Concise text, high-yield tables, clinical correlations, and review questions combine to make this new edition a perfect choice for learning and remembering the need-to-know structures, relationships, and concepts, while beautiful illustrations created in the Netter tradition enhance your visual mastery of the material. You may also be interested in: A companion set of flash cards, Netter's Advanced Head & Neck Anatomy Flash Cards, 3rd Edition. Over 100 multiple-choice questions complete with explanations help you assess your knowledge of the material and prepare for exams. Identify clinically relevant anatomy with Netter illustrations and new art created in the Netter tradition. Concise text and high-yield tables offer fast access to important facts. Procedures coverage gives context and clinical meaning to the anatomy. Expanded, up-to-date coverage on dental implants, cone beam imaging, and mandible osteology. Beautiful new illustrations by Carlos Machado, MD, of the TMJ, articular disc pathology, infratemporal fossa, pterygopalatine fossa, and maxillary artery. Interactive eBook included with print purchase, which includes access to the full text, interactive images, case studies, additional assessment questions, video clips from cone beam CTs, and a rotatable 3D skull.

Anatomy and Physiology: An Integrated Approach combines the study of anatomy and physiology into one well-organized and illustrated text. It teaches students about the purposes of organ systems, as well as their interconnections. It educates readers about interactions between systems and how disruption to a single system can impact overall function. The material in Anatomy and Physiology focuses on primary concepts and how to apply them. Linked learning strategies, section-specific references, and short summaries throughout each chapter emphasize and reiterate material to enhance learning and retention. Anatomically accurate, vibrant, realistic artwork helps readers visualize anatomic and physiological principles. Written as an integrative text, Anatomy and Physiology provides a consistent, balanced discussion of both anatomy and physiology within and across chapters. The book provides detailed information on the topics covered in the traditional, two-course sequence of college-level anatomy and physiology but avoids overwhelming readers with inessential information. It is suitable for courses on anatomy, physiology, and human biology, particularly those designed for programs in health care professions.

Now in its Second Edition, The Spinal Nerves and Autonomic Nervous System Illustrated Pocket Anatomy folding study guide takes the Anatomical Chart Company's most popular anatomical images and puts them in a durable, portable format that is perfect for the on-the-go student. Printed on a write-on, wipe-off laminated surface, this guide shows numbered anatomical structures and contains answers that can be concealed for easy self-testing and memorization. This edition features a fresh, clean design and improved organizational features such as key subject headers at the top of each panel. This quick reference includes: Spinal and cranial nerves Listing and description of important branches emerging from proximal part of spinal nerves Spinal cord segments Descriptions of nerve plexuses Cutaneous distribution of spinal nerves and dermatomes View of spinal cord with spinal nerves and immediate branches Autonomic nervous system, including sympathetic and parasympathetic nerves Listing of effector organs with sympathetic and parasympathetic action Size: 9" x 4" folded, unfolded 9" x 24" Made in USA Illustrated Pocket Anatomy Study Guides available on the following: Muscular and Skeletal Systems ISBN 9780781778783 Anatomy of the Heart ISBN 9780781776813 Vertebral Column and Spine Disorders ISBN 9780781779820 Anatomy of the Brain ISBN 9780781776837 Spinal Nerves and Autonomic Nervous System ISBN 9780781776844 Circulatory System ISBN 9780781779851 Anatomy and Disorders of the Respiratory System ISBN 9780781776868 Anatomy and Disorders of the Digestive System ISBN 9780781776882 Set of 8 Study Guides # PASET8

This atlas provides all the basic and advanced information required by surgeons in order to understand fully the skull base anatomy. It is organized according to anatomo-surgical pathways to the hidden areas of the skull base. These pathways are described in step-by-step fashion with the aid of a wealth of color images and illustrations. The emphasis is on endoscopic anatomy, but in order to provide a holistic perspective, informative three-dimensional reconstructions are presented alongside the endoscopic images and radiologic images are included when appropriate. In effect, windows are opened on the anatomy so that the reader is guided on a journey throughout the skull base region. This anatomically oriented atlas will serve as an ideal learning tool for novice surgeons and will also prove an invaluable reference for the more experienced surgeon

Cell-material interface plays a key role in the interaction of cells with artificial materials designed for construction of body implants or tissue engineering. Physical and chemical properties of the material surface, such as its polarity, wettability, electrical charge and conductivity, roughness and morphology, rigidity or elasticity as well as the presence of various chemical functional groups, strongly influence the cell adhesion. The latter is mediated by adsorption of cell adhesion-mediating molecules (eg: vitronectin, fibronectin, collagen, laminin, fibrinogen) from the serum of the culture medium or body fluids in appropriate spatial conformation or flexibility enabling the accessibility of specific sites on these molecules (eg: certain amino acid sequences or saccharide-based ligands) by adhesion receptors on the cell membrane (eg: integrins). After binding these ligands, the adhesion receptors are recruited into focal adhesion plaques, where they associate with cascades of various structural and signalling molecules, such as cytoskeletal proteins and kinases. By these cascades, the signal provided by the cell-material interaction is delivered to the cell nucleus. It influences the gene expression, and thus the further behavior of cells, manifested by their viability, synthesis of various molecules, proliferation, differentiation, functioning, immune activation, stress adaptation or cell death. This interdisciplinary review involves: (i) physical modifications of the material surface by plasma discharge, irradiation with ions or ultraviolet light and effects of these modifications on the surface wettability, electrical conductivity and formation of chemical functional groups influencing cell adhesion, (ii) deposition of organic or inorganic layers on the material surfaces, especially those nanostructured (eg: nanofibers of fibrin and extracellular matrix molecules, carbon nanoparticles, such as nanodiamonds, fullerenes and nanotubes, nanocomposite metal/C:H layers), (iii) functionalisation of the material surface with amino acids and oligopeptidic ligands for cell adhesion receptors (e.g., GRGDSG), (iv) effect of all these modifications on the extent and strength of adhesion of vascular and bone-derived cells, cell proliferation activity, switch between cell proliferation and differentiation, expression of cell-type specific markers of differentiation and other cell functions.

This book is a practical guide to the detection, diagnosis and treatment of infertility. Beginning with an overview of human reproduction, the importance of accurate history taking and examination, and general preconception evaluation, the following chapters discuss the different investigational methods in the assessment of female infertility. The final sections examine male infertility and the role of semen analysis in understanding the potential of fertility. Genetic, environmental and behavioural risk factors are also covered. This comprehensive text is enhanced by clinical images, diagrams and tables. Key Points Practical guide to detection, diagnosis and treatment of infertility Covers assessment of both female and male infertility Covers genetic, environmental and behavioural risk factors Enhanced by clinical images, diagrams and tables

This book is a concise guide to surface and radiological anatomy for undergraduate medical students. Divided into two sections, the first part introduces surface anatomy with a clinical perspective, followed by surface marking of various structures and organs in the thorax, abdomen, head and neck, and upper and lower limb. The second section provides an overview of radiology and discussion on new imaging techniques. The final chapters describe radiological anatomy of the same structures and organs as in part one. Each topic is explained in depth with applied anatomy, clinical findings and pathologies, differential diagnoses and surgical techniques. Key learning points are highlighted in boxes. The practical text is enhanced by nearly 200 anatomical diagrams and radiological images to assist learning. Key Points Concise guide to surface and radiological anatomy for undergraduates Covers various structures and organs throughout the body Key points highlighted in boxes Includes nearly 200 diagrams and radiological photographs

This clinically relevant anatomy flash card set is based on the concepts and full-color images in Moore's" ""Clinically Oriented Anatomy." The card set is a convenient, portable study tool for gross anatomy courses, exam preparation, clinical anatomy review during clerkships, and dental and allied health students.Organized and color-coded using the regional approach of "Clinically Oriented Anatomy," the cards feature descriptions of structures, concise versions of the text's clinical "Blue Boxes," and correlating images. Realistic anatomic renderings, radiographs, and diagrams of common medical situations complement this clinically oriented material. Information on muscle attachments, innervations, and main actions are also included.
New to this edition: 16 introductory cards that give an overview of the major systemsNew and improved artwork from the 7th edition of "Clinically Oriented Anatomy"Additional diagrams, illustrations, and clinical photosA hole punch and metal key ring for easy organization and studying on the go

A Synopsis of Regional Anatomy offers concise and essential knowledge on the human anatomy. Unlike other textbooks on anatomy, this book is arranged in regions rather than in systems. As such, it is more consistent with the prevailing approaches to clinical examination and regional surgery as well as directing attention towards the principles of body function and organization. It is divided into eight regions that can be studied either collectively or in isolation. Factual information is presented for typical areas defined by fascial compartments; muscles are described in functional groups; blood vessels, lymphatic vessels, and nerves of the area are discussed; and regional landmarks, their boundaries, and contents important in clinical examination are explained. Written in a format that encourages self-directed learning, this book will be a valuable reference for self-study and also as a guide for dissection in the laboratory.

The world's most trusted clinically focused anatomy text! Renowned for comprehensive coverage, the best-selling Clinically Oriented Anatomy guides students from initial anatomy and foundational science courses through clinical training and practice. The eighth edition reflects significant new information and updates and maintains the highest standards for scientific and clinical accuracy. Comprehensive updates reflect changes in the clinical application of anatomy as well as new imaging technologies, focusing on the anatomy that students need to know. Extensively revised "Clinical Blue Boxes" explore the practical applications of anatomy, and helpful icons distinguish the type of clinical information covered in each. Clinically relevant anatomy focuses on physical diagnosis, interpretation of diagnostic imaging, and understanding the anatomical basis of emergency medicine and general surgery. Insightfully rendered, anatomically accurate illustrations, with updates throughout , make this book an aesthetically rewarding learning resource. Combined with many photographs and medical images, these stunning visuals facilitate comprehension of anatomical concepts and retention of "mental images" of anatomical structures. New and updated medical imaging and integrated surface anatomy within each chapter demonstrates the relationship between anatomy, physical examination, and diagnosis. Expanded "Overview and Basic Concepts" chapter includes functional systemic anatomy summaries and introduces approaches to studying anatomy, terminology, imaging, and more. Inclusion of new sections describing the enteric nervous system (considered by some as a "second brain") and its unique role in the innervation of the digestive system gives students cutting-edge insight into this significant scientific discovery. A more realistic approach to the musculoskeletal system explores the action and use of muscles and muscle groups in daily activities, emphasizing gait and grip. "Bottom Line" boxes summarize information to facilitate ongoing review and underscore the big-picture viewpoint. Clinical Blue Box animations, case studies, and interactive multiple-choice questions online at thePoint.lww.com facilitate review and self-testing.

A Synopsis of Regional Anatomy offers concise and essential knowledge on the human anatomy. Unlike other textbooks on anatomy, this book is arranged in regions rather than in systems. As such, it is more consistent with the prevailing approaches to clinical examination and regional surgery as well as directing attention towards the principles of body function and organization. It is divided into eight regions that can be studied either collectively or in isolation. Factual information is presented for typical areas defined by fascial compartments; muscles are described in functional groups; blood vessels, lymphatic vessels, and nerves of the area are discussed; and regional landmarks, their boundaries, and contents important in clinical examination are explained. Written in a format that encourages self-directed learning, this book will be a valuable reference for self-study and also as a guide for dissection in the laboratory.

The year 1818 saw the publication of one of the most influential science-fiction stories of all time. Frankenstein: Or, Modern Prometheus by Mary Shelley had a huge impact on gothic horror and science-fiction genres, and her creation has become part of our everyday culture, from cartoons to Hallowe'en costumes. Even the name 'Frankenstein' has become a by-word for evil scientists and dangerous experiments. How did a teenager with no formal education come up with the idea for an extraordinary novel such as Frankenstein?

Clues are dotted throughout Georgian science and popular culture. The years before the book's publication saw huge advances in our understanding of the natural sciences, in areas such as electricity and physiology, for example. Sensational science demonstrations caught the imagination of the general public, while the newspapers were full of lurid tales of murderers and resurrectionists.

Making the Monster explores the scientific background behind Mary Shelley's book. Is there any science fact behind the science fiction? And how might a real-life Victor Frankenstein have gone about creating his monster? From tales of volcanic eruptions, artificial life and chemical revolutions, to experimental surgery, 'monsters' and electrical experiments on human cadavers, Kathryn Harkup examines the science and scientists that influenced Shelley, and inspired her most famous creation.

This set of volumes is a companion to a program, supplemented by lectures and dissection, on the study of human anatomy. Each volume highlights important general concepts of anatomy and lists the structures in context that must be understood in a study program. The coverage caters for the needs of students of medical and paramedical disciplines. Emphasis is on carefully organizing major regions and promoting focused active learning through accurate labeling of anatomical drawings and posing clinical questions.

This set of volumes is a companion to a program, supplemented by lectures and dissection, on the study of human anatomy. Each volume highlights important general concepts of anatomy and lists the structures in context that must be understood in a study program. The coverage caters for the needs of students of medical and paramedical disciplines. Emphasis is on carefully organizing major regions and promoting focused active learning through accurate labeling of anatomical drawings and posing clinical questions.

This set of volumes is a companion to a program, supplemented by lectures and dissection, on the study of human anatomy. Each volume highlights important general concepts of anatomy and lists the structures in context that must be understood in a study program. The coverage caters for the needs of students of medical and paramedical disciplines. Emphasis is on carefully organizing major regions and promoting focused active learning through accurate labeling of anatomical drawings and posing clinical questions.