Quasispecies: From Theory to Experimental Systems (Paperback, Softcover reprint of the original 1st ed. 2016)

This volume brings together recent developments in quasispecies theory extended to variable environments and practical applications in elucidating viral dynamics and treatment designs. In particular, the existence of an error threshold in rugged fitness landscapes has opened the way to a new antiviral strategy termed lethal mutagenesis, which is now under intensive theoretical, experimental and clinical investigation. As such the book explains how an understanding of quasispecies dynamics within infected organisms has increased our knowledge of viral disease events. From a clinical perspective, population dynamics highlights important problems for viral disease control, such as the selection of drug-resistant mutants that often accompanies treatment failures, and suggests means of increasing the effectiveness of antiviral treatments. The book is intended for students and scientists interested in basic and applied aspects of biophysics, chemistry, biology, evolution and medical virology.

General

Imprint:	Springer International Publishing AG
Country of origin:	Switzerland
Series:	Current Topics in Microbiology and Immunology, 392
Release date:	April 2018
First published:	2016
Editors:	Esteban Domingo • Peter Schuster
Dimensions:	235 x 155 x 20mm (L x W x T)
Format:	Paperback
Pages:	357
Edition:	Softcover reprint of the original 1st ed. 2016
ISBN-13:	978-3-319-79548-5
Categories:	Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics Books > Science & Mathematics > Biology, life sciences > General Books > Medicine > Pre-clinical medicine: basic sciences > Anatomy > General Books > Medicine > Other branches of medicine > Pathology > Medical microbiology & virology Books > Medicine > Clinical & internal medicine > Diseases & disorders > Infectious & contagious diseases > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General
LSN:	3-319-79548-1
Barcode:	9783319795485

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