Key features: High quality full color photographs and descriptive texts on the location and removal of the organs from the mouse Instructive methods and clear visuals for trimming and orienting the organs for paraffin histology to obtain the best possible sections for analysis Full color photomicrographs of the resulting section for each organ stained with hematoxylin and eosin demonstrating important features and landmarks for the histologist to ensure the optimal area for analysis is achieved All in one, easy to use guide organized by individual organs of the laboratory mouse Spiralbound for easy reference in the lab This "one-stop" guide offers an essential resource for any academic, research or development operation where mouse necropsy and/or histology are performed. Connecting the reader 'from the mouse to the microscope', it provides a detailed guide for locating, trimming, orientating and embedding of the most frequently investigated tissues collected in the laboratory mouse. It shows where the organs reside in the mouse, how to trim and embed them as well as the resulting optimal sections. This guide brings together the wealth of scattered information into one high-quality text, the emphasis is on providing knowledge that will help histologists and scientists get better results in any downstream assays where ideal sections are needed.

Combining detailed descriptions of pelvic anatomy with easy-to-follow instructions for gynecologic procedures, Atlas of Pelvic Anatomy and Gynecologic Surgery, 5th Edition, is a comprehensive, up-to-date atlas that reflects current practices in this fast-changing field. Pelvic anatomy and surgical operations are depicted through full-color anatomic drawings, correlative surgical artwork with step-by-step photographs, and computer-assisted hybrid photo illustrations. Complete coverage of both conventional and endoscopic surgeries helps you master the full spectrum of surgical procedures. Covers all frequently performed gynecologic operations including laparotomy, laparoscopic, robotic, hysteroscopic, vaginal, vulvar, and cystoscopic procedures. Includes expanded sections on gender reassignment surgery and vulvar and cervical surgery, as well as a new chapter devoted to laparoscopic techniques. Contains a revised anatomic section with updated figures, plus high-quality artwork and clinical photographs throughout-now entirely in full color. Features numerous videos of surgeries and cadaver dissection. Ideal for practicing obstetricians-gynecologists, obstetrics-gynecology residents, general surgeons, subspecialists, nurses, and medical students with an interest in gynecology. Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices.

This work presents the notion of consciousness as it can be described and understood by contemporary neuroscience without ignoring its traditional philosophical context. It discusses the problem of how the workings of synaptic connections might give rise to consciousness and describes the current neuroscientific concepts and techniques used to identify and explore those parts of the human brain that may be involved. This book is intended as an introduction to the subject.

Examines how the body - its organs, limbs, viscera - was represented in the literature and culture of early modern Europe. Why did 16th and 17th century medical, religious, and literary texts portray the body part by part, rather than as an entity? And what does this view of the human body tell us about society's view of part and whole, of individual and universal in the early modern period? As this volume demonstrates, the symbolics of body parts challenges our assumptions about "the body" as a fundamental Renaissance image of self, society, and nation. The book presents work by: Nancy Vickers on corporeal fragments; Peter Stallybrass on the foot; Marjorie Garber on joints; Stephen Greenblatt on bodily marking and mutilation; Gail Kern Paster on the nervous system; Michael Schoenfeldt on the belly; Jeffrey Masten on the anus; Katherine Park on the clitoris; Kathryn Schwartz on the breast; Sergei Lobanov-Rostovsky on the eye; Katherine Rowe on the hands; Scott Stevens on the heart and brain; Carla Mazzio on the tongue; and David Hillman on the entrails.

The Body Emblazoned is a compelling study of the culture of dissection in the English Renaissance which informed intellectual enquiry in Europe for nearly two hundred years. It provides a richly interdisciplinary framework for conceptualizing the body in literature, art, and the domains of the religious, the moral, the medical and the political.

This volume is based on presentations by the world-renowned investigators who gathered at the 74th annual Cold Spring Harbor Symposium on Quantitative Biology to celebrate the 150th anniversary of the publication of Charles Darwin's On the Origin of Species. It reviews the latest advances in research into evolution, focusing on the molecular bases for evolutionary change. The topics covered include the appearance of the first genetic material, the origins of cellular life, evolution and development, selection and adaptation, and genome evolution. Human origins, cognition, and cultural evolution are also covered, along with social interactions. The line-up of speakers comprised a stellar list of preeminent scientists and thinkers such as the zoologist and prolific author E. O. Wilson (Harvard University); Jack W. Szostak (Harvard Medical School), a 2009 Nobel Prize winner who studies the chemistry of life's origins; and Nobel Prize winner and former president of HHMI Thomas Cech (Colorado Institute for Molecular Biotechnology), to name just a few.

Core Anatomy offers a thorough yet concise explanation of all aspects of anatomy essential to students. Volume I covers the upper limb--shoulder, upper arm and elbow joint, forearm, wrist, hand and digits, and front of the forearm; the lower limb--front and sides of the thigh, gluteal region and hip joint, back of the thigh, popliteal fossa and knee joint, leg, ankle, and foot; and the vertebral column--vertebral column, and the spinal cord.

Comparative Cardiovascular Dynamics of Mammals offers never-before-published data on the structure and function of the circulatory systems of the different mammalian species. This text explores classic allometry, dimensional analysis, and modern hemodynamics to establish similarity principles that provide a necessary and important step in understanding the natural common design and functional features of the cardiovascular systems of different mammals. Fluid and blood vessel mechanics, pulse transmission characteristics, cardiac energetics and mechanics, as well as heart-arterial system interaction are included in this essential reference. The sensitivity of parameters and similarity of principles in the diagnosis of cardiovascular diseases are also addressed. This book also describes the natural processes involved in the functional development of the mammalian cardiovascular system. By using modern methods to present recent findings on the similarities and differences of the mammalian cardiovascular system, the author provides an easily understood approach to this dynamic field of study.

Praise for the First Edition "This book is easy to read and has many informative illustrations...I would strongly recommend this book to those interested in a broad introduction to the care and use of laboratory guinea pigs as well as to laboratory animal technicians, managers, veterinarians and scientists who do not have direct access to large, well organized animal resource units with extensive library facilities." -John D. Young, Contemporary Topics The Laboratory Guinea Pig provides a compact and well- illustrated introduction to research on the guinea pig. The second edition of this popular handbook facilitates quick reference to the behavioral and physical traits of the guinea pig, as well as practical information on its unique anatomical and biological features. Numerous tables and color illustrations help the reader identify features of anatomy and understand health issues and care requirements. Supplying a stepwise introduction to common laboratory techniques, the new edition of this trusted reference provides guidance that supports the humane care and use of guinea pigs in the laboratory setting.

An outstanding piece of interdisciplinary scholarship, "The Body Emblazoned" is a study of the Renaissance culture of dissection which informed intellectual inquiry in Europe for nearly two hundred years. Though the dazzling displays in Renaissance art and literature of the "exterior" of the body have long been a subject of enquiry, Jonathan Sawday considers in detail the "interior" of the body, and what it meant to men and women in early modern culture.
Sawday links the frequently illicit activities of the great anatomists of the period, to whose labors we are indebted for so much of our understanding of the structure and operation of the human body, to a wider cultural discourse which embraces not only the great moments of Renaissance art, but the very foundation of a modern idea of knowledge. Illustrated with thirty-two black and white prints, "The Body Emblazoned" re-assesses modern understanding not only of the literature and culture of the Renaissance, but of the modern organization of knowledge which is now so familiar that it is only rarely questioned.

Get a multi-dimensional understanding of musculoskeletal anatomy with Anatomy Trains: Myofascial Meridians for Manual Therapists and Movement Professionals, 4th Edition. This hugely successful, one-of-a-kind title continues to center on the application of anatomy trains across a variety of clinical assessment and treatment approaches - demonstrating how painful problems in one area of the body can be linked to a "silent area" away from the problem, and ultimately giving rise to new treatment strategies. This new fourth edition has been fully updated with the latest evidence-based research and includes new coverage of anatomy trains in motion using Pilates-evolved movement, anatomy trains in horses and dogs, and the updated fascial compendium on elements, properties, neurology, and origins of the fascial system. This new edition also features an enhanced eBook format included with purchase as well as new photos and images throughout both text versions. In all, this unique exploration of the role of fascial in healthy movement and postural distortion is an essential read for physical therapists, massage therapists, craniosacral therapists, yoga instructors, osteopathologists, manual therapists, athletic and personal trainers, dance instructors, chiropractors, acupuncturists, and any professional working in the field of movement. Revolutionary approach to the study of human anatomy provides a holistic map of myoanatomy to help improve the outcomes of physical therapies that are traditionally used to manage pain and other musculoskeletal disorders. Relevant theory descriptions are applied to all common types of movement, posture analysis, and physical treatment modalities. Intuitive content organization allows students to reference the concept quickly or gain a more detailed understanding of any given area according to need. Section on myofascial force transmission in gait dynamics is written by guest author James Earls. Robust appendices discuss the relevance of the Anatomy Trains concept to the work of Dr Louis Schultz (Meridians of Latitude), Ida Rolf (Structural Integration), and correspondences with acupuncture meridians. New photos and images of fascial tissues, adhesions, and layers provide a better understanding of text content. Revised and expanded content reflects the most up-to-date research and latest evidence for the scientific basis of common clinical findings. New, larger library of videos includes animations and webinars with the author. New Anatomy Trains in Motion section by guest author Karin Gurtner uses Pilates-evolved movement to explore strength and plasticity along myofascial meridians. New addition: Anatomy Trains in Quadrupeds (horses and dogs) is mapped for equine and pet therapies by Rikke Schultz, DVM, Tove Due, DVM, and Vibeke Elbrond, DVM, PhD. New appendix: Updated fascial compendium on elements, properties, neurology, and origins of the fascial system. NEW! enhanced eBook version is included with print purchase, which allows students to access all of the text, figures, and references from the book on a variety of devices.

The series CNS Neurotransmitters and Neuromodulators is destined to be the definitive reference work on the physiology and pharmacology of the central nervous system. Written by an outstanding group of international authors, chapters cover a wide range of interdisciplinary aspects of the subject.
This first volume includes an in-depth examination of acetylcholine, ranging from the localization of synthetic enzymes through electrophysiology, pharmacology, and molecular biology to behavioral importance in learning and memory. This indispensable and comprehensive reference keeps you abreast of new developments in several areas of neuroscience.

Science is a force for good in the world-at least usually. But sometimes, when obsession gets the better of scientists, they twist a noble pursuit into something sinister. Under this spell, knowledge isn't everything, it's the only thing-no matter the cost. Bestselling author Sam Kean tells the true story of what happens when unfettered ambition pushes otherwise rational men and women to cross the line in the name of science, trampling ethical boundaries and often committing crimes in the process. The Icepick Surgeon masterfully guides the reader across two thousand years of history, beginning with Cleopatra's dark deeds in ancient Egypt. The book reveals the origins of much of modern science in the transatlantic slave trade of the 1700s, as well as Thomas Edison's mercenary support of the electric chair and the warped logic of the spies who infiltrated the Manhattan Project. But the sins of science aren't all safely buried in the past. Many of them, Kean reminds us, still affect us today. We can draw direct lines from the medical abuses of Tuskegee and Nazi Germany to current vaccine hesitancy, and connect icepick lobotomies from the 1950s to the contemporary failings of mental-health care. Kean even takes us into the future, when advanced computers and genetic engineering could unleash whole new ways to do one another wrong. Unflinching, and exhilarating to the last page, The Icepick Surgeon fuses the drama of scientific discovery with the illicit thrill of a true-crime tale. With his trademark wit and precision, Kean shows that, while science has done more good than harm in the world, rogue scientists do exist, and when we sacrifice morals for progress, we often end up with neither.

A laboratory manual and an anatomy review, this text is written specifically for students in the allied health sciences who are studying human muscoloskeletal anatomy. It takes a classic regional approach to the study of human anatomy which has proved a practical learning tool for the student.

In this book
Neuroanatomy and the Neurologic Exam is an innovative, comprehensive thesaurus that surveys terminology from neuroanatomy and the neurologic examination, as well as related general terms from neurophysiology, neurohistology, neuroembryology, neuroradiology, and neuropathology. The author prepared the thesaurus by examining how terms were used in a large sample of recent, widely used general textbooks in basic neuroanatomy and clinical neurology. These textbooks were written by experts who received their primary professional training in 13 different countries, allowing the thesaurus to incorporate synonyms and conflicting definitions that occur as a result of variations in terminology used in other countries. The thesaurus contains:

This reference work brings together the biology, mechanics, neurophysiology and pathophysiology of diseased joints, illustrates available physiologically-based treatments for osteoarthrosis and explains how and when to use them.;Highlighting the most up-to-date biomechanical principles, Mechanics of Human Joints: discusses the functional anatomy of joints; relates the neurophysiology of joints to ligamentous reconstruction; elucidates the pathophysiology of osteoarthrosis; summarizes the latest information on muscle physiology and electromyography; examines the effect of vibration and impulsive loading on joint pathology; and explicates the principles of prosthetic joint replacement.

Molecular and Cell Biology of Human Diseases reviews the status of research on a range of sexually transmitted diseases whose incidence has paralleled the increase in HIV infection and examines the ways in which new methods are influencing current practice and are likely to shape future management.

Focusing on all the major cytokine families, this reference book provides coverage of cytokine regulatory processes in the lung and other tissues and comprehensive descriptions of cytokine functions specific to the lung.;Discussing the diverse cytokine-binding proteins and the role of cytokines in tissue injury and repair processes and extracellular matrix regulations, the book supplies information on amino acid structure and gene regulatory sequences, examines the receptor biology of individual cytokines, illustrates cytokine interactions with their cognate receptors and surveys the phenotypic effects of individual cytokines on target cells. With over 2700 literature citations and figures, this book is a resource for pulmonologists, physiologists, immunologists, cell and molecular biologists, environmental toxicologists, oncologists, and graduate-level and medical school students in these disciplines.

Calcification in Biological Systems provides a collection of up-to-date papers regarding calcification in a variety of biological systems. The papers are not simple reviews of the literature. Each paper reflects the personal experience of the author(s) and is rich in constructive criticism and suggestions. Topics range from basic molecular processes to general structural problems in systems as different as unicellular organisms and human skeletal tissues. Because calcification is so diffuse in the animal kingdom, this book makes no attempt to achieve a conclusive synthesis of available results and current ideas. Instead, its merit lies in its ability to be useful to investigators with different scientific backgrounds and areas of interest.

The authors of the most cited neuroscience publication, "The Rat Brain in Stereotaxic Coordinates," have written this introductory textbook for neuroscience students. The text is clear and concise, and offers an excellent introduction to the essential concepts of neuroscience.

Based on contemporary neuroscience research rather than old-style medical school neuroanatomy

Thorough treatment of motor and sensory systems

A detailed chapter on human cerebral cortex

The neuroscience of consciousness, memory, emotion, brain injury, and mental illness

A comprehensive chapter on brain development

A summary of the techniques of brain research

A detailed glossary of neuroscience terms

Illustrated with over 130 color photographs and diagrams

This book will inspire and inform students of neuroscience. It is designed for beginning students in the health sciences, including psychology, nursing, biology, and medicine.
Clearly and concisely written for easy comprehension by beginning students

Based on contemporary neuroscience research rather than the concepts of old-style medical school neuroanatomy

Thorough treatment of motor and sensory systems

A detailed chapter on human cerebral cortex

Discussion of the neuroscience of conscience, memory, cognitive function, brain injury, and mental illness

A comprehensive chapter on brain development

A summary of the techniques of brain research

A detailed glossary of neuroscience terms

Illustrated with over 100 color photographs and diagrams

Presents a sampling of new and novel approaches to the amelioration of musculoskeletal disease pathology, emphasizing prevention and therapy. Where applicable, these new technologies are focused on their application to human autoimmune diseases, but the volume mainly discusses and details the use of

The eminent physician and anatomist Dr William Hunter (1718-1783) made an important and significant contribution to the history of collecting and the promotion of the fine arts in Britain in the eighteenth century. Born at the family home in East Calderwood, he matriculated at the University of Glasgow in 1731 and was greatly influenced by some of the most important philosophers of the Scottish Enlightenment, including Francis Hutcheson (1694-1746). He quickly abandoned his studies in theology for Medicine and, in 1740, left Scotland for London where he steadily acquired a reputation as an energetic and astute practitioner; he combined his working life as an anatomist successfully with a wide range of interests in natural history, including mineralogy, conchology, botany and ornithology; and in antiquities, books, medals and artefacts; in the fine arts, he worked with artists and dealers and came to own a number of beautiful oil paintings and volumes of extremely fine prints. He built an impressive school of anatomy and a museum which housed these substantial and important collections. William Hunter's life and work is the subject of this book, a cultural-anthropological account of his influence and legacy as an anatomist, physician, collector, teacher and demonstrator. Combining Hunter's lectures to students of anatomy with his teaching at the St Martin's Lane Academy, his patronage of artists, such as Robert Edge Pine, George Stubbs and Johan Zoffany, and his associations with artists at the Royal Academy of Arts, the book positions Hunter at the very centre of artistic, scientific and cultural life in London during the period, presenting a sustained and critical account of the relationship between anatomy and artists over the course of the long eighteenth century.

Focusing on the essentials, McMinn's Concise Human Anatomy is a convenient, portable guide and revision aid. The clear, jargon-free text is supported by high-quality, labelled photographs of cadaver dissections and surface anatomy, radiological images captured using the latest technologies and explanatory line diagrams, all redrawn for this edition. Providing full explanations of difficult anatomical relationships, and highlighting features of clinical significance throughout, this second edition remains an invaluable guide for students of anatomy across the medical and health sciences, and a handy reference for the busy clinician.

Focusing on the essentials, McMinn's Concise Human Anatomy is a convenient, portable guide and revision aid. The clear, jargon-free text is supported by high-quality, labelled photographs of cadaver dissections and surface anatomy, radiological images captured using the latest technologies and explanatory line diagrams, all redrawn for this edition. Providing full explanations of difficult anatomical relationships, and highlighting features of clinical significance throughout, this second edition remains an invaluable guide for students of anatomy across the medical and health sciences, and a handy reference for the busy clinician.