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Books > Medicine > Clinical & internal medicine > Medical diagnosis > General
Volume 69 in the internationally acclaimed Advances in Clinical Chemistry contains chapters authored by world renowned clinical laboratory scientists, physicians and research scientists. The serial provides the latest and most up-to-date technologies related to the field of Clinical Chemistry and is the benchmark for novel analytical approaches in the clinical laboratory.
Drs. Elizabeth Morris and Laura Liberman, two rising stars in breast MRI from the Memorial Sloan-Kettering Cancer Center, edited this complete, superbly illustrated practical guide. The comprehensive text is written by contributors from the top cancer centers in the world. Introductory chapters are devoted to diagnosis and cover the basics of performing breast MRI exams, setting up a breast MR program, and understanding clinical indications. Additional chapters discuss breast interventional procedures, including the surgeon's use of MR and MR-guided needle interventions. A comprehensive diagnostic atlas completes the volume and addresses the spectrum of clinical situations, such as various carcinomas, special tumor types, and benign histologies. Radiologists, residents, and fellows will benefit from this guide's thorough examination of image interpretation, which highlights pitfalls that specialists must recognize.
This volume presents several machine intelligence technologies, developed over recent decades, and illustrates how they can be combined in application. One application, the detection of dementia from patterns in speech, is used throughout to illustrate these combinations. This application is a classic stationary pattern detection task, so readers may easily see how these combinations can be applied to other similar tasks. The expositions of the methods are supported by the basic theory they rest upon, and their application is clearly illustrated. The book's goal is to allow readers to select one or more of these methods to quickly apply to their own tasks. Includes a variety of machine intelligent technologies and illustrates how they can work together Shows evolutionary feature subset selection combined with support vector machines and multiple classifiers combined Includes a running case study on intelligent processing relating to Alzheimer's / dementia detection, in addition to several applications of the machine hybrid algorithms
In recent years, advanced molecular techniques in diagnostic microbiology have been revolutionizing the practice of clinical microbiology in the hospital setting. Molecular diagnostic testing in general and nucleic acid-based amplification methods in particular have been heralded as diagnostic tools for the new millennium. This third edition covers not only the most recent updates and advances, but details newly invented omic techniques, such as next generation sequencing. It is divided into two distinct volumes, with Volume 1 describing the techniques, and Volume 2 addressing their applications in the field. In addition, both volumes focus more so on the clinical relevance of the test results generated by these techniques than previous editions.
This book presents a comprehensive, state-of the-art guide and review of ultrasound applications for children and infants with surgical problems. It is meant as a single source to provide information about sonographic application, interpretation and technique for a diversity of pediatric surgical care providers, making it a useful tool for the ultrasound novice as well as the more advanced ultrasonographer. Sections address initial obstacles faced by a physician starting with ultrasound such as the scanning techniques, underlying anatomy and normal sonographic findings. The initial chapter provides an introduction and basic overview about ultrasound theory and techniques. Subsequent chapters focus on specific body parts and systems and their disease processes as it pertains to pediatric and neonatal patients. The text also includes a chapter on abdominal trauma and its evaluation with the FAST (focused abdominal sonography for trauma) exam. Diagnostic and Interventional Ultrasound in Pediatric Surgery serves as a useful resource for a broad spectrum of pediatric care providers, including a growing number of ultrasound users, surgeons and pediatricians alike.
Health surveillance and intelligence play an important role in modern health systems as more data must be collected and analyzed. It is crucial that this data is interpreted and analyzed effectively and efficiently in order to assist with diagnoses and predictions. Diagnostic Applications of Health Intelligence and Surveillance Systems is an essential reference book that examines recent studies that are driving artificial intelligence in the health sector and helping practitioners to predict and diagnose diseases. Chapters within the book focus on health intelligence and how health surveillance data can be made useful and meaningful. Covering topics that include computational intelligence, data analytics, mobile health, and neural networks, this book is crucial for healthcare practitioners, IT specialists, academicians, researchers, and students.
Your essential guide in the assessment and diagnostic process. Step by step, you’ll hone your ability to perform effective health assessments, obtain valid data, interpret the findings, and recognize the range of conditions that can be indicated by specific findings to reach an accurate differential diagnosis. You’ll have coverage of 170 conditions and symptoms across the lifespan at your fingertips. Expanded, Revised & Updated! Thoroughly updated to reflect the art and the science of primary care practice as well as the newest evidence and changes in health care New Chapter!Differential Studies New & Expanded! Content in Chapter 1 on history taking-techniques and skills for special populations Expanded! Lab diagnostics information, as well as discussions of health disparities, cultural humility, and competency New Content! Genetic testing for pharmacologic prescriptions for psychiatric mental health conditions New! Diagnosis algorithm decision trees designed to help nurses assess and diagnose conditions such as chronic sore throat, chronic insomnia, and more Coverage of 170 conditions and symptoms across the life span—including children, older adults, and pregnant patients. Complaint-focused approach organized by body system, including discussions of complex conditions Step-by-step how tos for taking a focused history, performing a physical based on presenting complaints/problems, and interpreting the findings Guidance on selecting diagnostic tests and interpreting those studies to help narrow down the diagnoses Prediction rules for selected disorders Quick-reference features, including red flags ÿ assessment pearls ÿ medications causing symptoms ÿ and selected causes of symptoms
Based on George Engel's model, The Biopsychosocial Formulation Manual presents ways to help psychiatry residents and students effectively gather and organize patient data to arrive at a complete mental health history in a limited timeframe. While most current models only take one factor into account, Campbell and Rohrbaugh emphasize and analyze three essential components (biological, social, and psychological). The process of identifying pertinent data for each component of the biopsychosocial formulation is explicated in detail. A separate section outlines how to use the biopsychosocial formulation to generate treatment recommendations. This volume includes a complete package for practicing the biopsychosocial method; this easy-to-use guide includes a data record sheet and downloadable resources to facilitate organization and assessment, appealing to both the psychiatric professional and the trainee.
Advanced conceptual modeling techniques serve as a powerful tool for those in the medical field by increasing the accuracy and efficiency of the diagnostic process. The application of artificial intelligence assists medical professionals to analyze and comprehend a broad range of medical data, thus eliminating the potential for human error. Medical Diagnosis Using Artificial Neural Networks introduces effective parameters for improving the performance and application of machine learning and pattern recognition techniques to facilitate medical processes. This book is an essential reference work for academicians, professionals, researchers, and students interested in the relationship between artificial intelligence and medical science through the use of informatics to improve the quality of medical care.
The molecular and genetic signatures of cancer are represented in the peripheral circulation and other body fluids, giving rise to the "liquid biopsy" concept. This new paradigm of molecular profiling of cancer cells offers several advantages over traditional tissue biopsy. It is convenient, noninvasive, conforms to current clinical practice, enables real time disease monitoring and the study of tumor evolution, can easily be sampled multiple times, and this sample is more representative of the heterogeneous cancer cells than biopsy sampling. Indeed, all aspects of cancer molecular genetic information, stemming from DNA (both nuclear and mitochondria), RNA (coding and noncoding), peptides and proteins, metabolites and lipids are present in body fluids as free, cell surface bound or enclosed in membrane vesicles, and are being harnessed for disease management. Additionally, circulating tumor, and tumor stem cells provide prognostic information, and also enable the study of the intricate molecular processes associated with metastasis and drug resistance. This treatise deals with the general principles of the molecular pathology of cancer, and its associated imprints in circulation. The transitional process from discovery, prototype development, translational research, to product development can be complex and costly. The critical path to biomarker development and qualification for successful use in drug development is detailed herein as well. This book is of interest to Cancer Researchers, Oncologists, Clinicians, Surgeons, Medical Students, Nurses, Diagnostic Laboratories, and Pharmaceutical Industries.
To effectively serve minority clients, clinicians require a double understanding: of both evidence-based practice and the cultures involved. This particularly holds true when working with Asian-Americans, a diverse and growing population. The Guide to Psychological Assessment with Asians synthesizes real-world challenges, empirical findings, clinical knowledge and common-sense advice to create a comprehensive framework for practice. This informed resource is geared toward evaluation of first-generation Asian Americans and recent immigrants across assessment methods (self-report measures, projective tests), settings (school, forensic) and classes of disorders (eating, substance, sexual). While the Guide details cross-cultural considerations for working with Chinese-, Japanese-, Korean and Indian-American clients, best practices are also included for assessing members of less populous groups without underestimating, overstating or stereotyping the role of ethnicity in the findings. In addition, contributors discuss diversity of presentation within groups and identify ways that language may present obstacles to accurate evaluation.Among the areas covered in this up-to-date reference: * Structured and semi-structured clinical interviews.* Assessment of acculturation, enculturation and culture.* IQ testing.* Personality disorders.* Cognitive decline and dementia.* Mood disorders and suicidality.* Neuropsychological assessment of children, adolescents and adults.* Culture-bound syndromes. Designed for practitioners new to working with Asian clients as well as those familiar with the population, the Guide to Psychological Assessment with Asians is exceedingly useful to neuropsychologists, clinical psychologists, health psychologists and clinical social workers.
Amyotrophic Lateral Sclerosis presents the most comprehensive, clinically-focused information on ALS (Lou Gehrig's disease) in print. The three authors, widely known for their work in this area, provide cohesive and balanced coverage of this syndrome, including the history, clinical features, pathology and pathogenesis, treatment and management of ALS. To facilitate understanding, each chapter is enhanced by comprehensive tables and figures, as well as detailed chapter summaries.
The development of fuzzy expert systems has provided new opportunities for problem solving amidst uncertainties. The medical field, in particular, has benefitted tremendously from advancing fuzzy system technologies. Fuzzy Expert Systems for Disease Diagnosis highlights the latest research and developments in fuzzy rule-based methods used in the detection of medical complications and illness. Offering emerging solutions and practical applications, this timely publication is designed for use by researchers, academicians, and students, as well as practitioners in the medical field.
Immunocytochemistry and in situ hybridization are widely used biomedical sciences. They are essential in medical diagnosis and in cell biology research. Affinity labeling is the central goal of the experimental strategy involving a series of techniques in a logical order; from the effects of specimen fixation, through specimen preparation to expose the antigen, to optimizing immunolabeling, to assessing the result and finally to safety considerations. Numerous examples of these techniques in biomedical sciences are included, as well as experimental assays and practical tips. This survey of methods will serve as an invaluable reference source in any laboratory setting (academic, industrial or clinical) involved in research in almost every branch of biology or medicine, as well as in pharmaceutical, biotechnological and clinical applications.
The book presents a knowledge discovery based approach to build a recommender system supporting a physician in treating tinnitus patients with the highly successful method called Tinnitus Retraining Therapy. It describes experiments on extracting novel knowledge from the historical dataset of patients treated by Dr. P. Jastreboff so that to better understand factors behind therapy's effectiveness and better personalize treatments for different profiles of patients. The book is a response for a growing demand of an advanced data analytics in the healthcare industry in order to provide better care with the data driven decision-making solutions. The potential economic benefits of applying computerized clinical decision support systems include not only improved efficiency in health care delivery (by reducing costs, improving quality of care and patient safety), but also enhancement in treatment's standardization, objectivity and availability in places of scarce expert's knowledge on this difficult to treat hearing disorder. Furthermore, described approach could be used in assessment of the clinical effectiveness of evidence-based intervention of various proposed treatments for tinnitus.
"This much-needed volume brings to the clinician or student some of the best critical-minded analysis by some of the most insightful thinkers about psychiatric diagnosis today. The thought-provoking questions these essays raise, and the multifaceted and provocative answers they provide, cultivate sensitivity to the nuances of diagnostic assessment that often makes the difference between clinical success and failure." - Jerome C. Wakefield, PhD, DSW, New York University Silver School of Social Work, New York This transformative resource challenges social workers and mental health professionals to rethink their approaches to assessment and diagnosis from the ground up. Among the book's unique features are its use of diverse lenses to examine a common case and its illustration of how multiple perspectives can be integrated for a richly textured portrait of the individual in context. Equally crucial is the book's commitment to professional development, from exercises to improve case conceptualization to strategies for teaching and learning. Topics include: The DSM-5 definition of mental disorder: critique and alternatives. Making assessment decisions: macro, mezzo, and micro perspectives. Neuroscience, resilience, and the embodiment of "mental" disorder. Narrative, psychodynamic, and cultural conceptualizations of disorder. Person-centered and contextualized diagnosis in mental health. Meeting the challenge of teaching integrated assessment. Critical Thinking in Clinical Assessment and Diagnosis has much to offer professionals, researchers, and educators in the fields of social work and mental health. .
Technological developments in the life sciences confront us with new facets of a Faustian seduction. Are we "playing God" more and more, as claimed by critical authors of modernity? Achievements in genetic research produce ethical dilemmas which need to be the subject of reflection and debate in modern societies. Denial of ambivalences that ethical dilemmas arouse constitutes a threat to societies as well as to individuals. The book presents a compilation of some of the results of the interdisciplinary European study "Ethical Dilemmas Due to Prenatal and Genetic Diagnostics" (EDIG), which investigated some of these dilemmas in detail in a field which is particularly challenging: prenatal diagnosis. When results from prenatal diagnosis show fetal abnormalities, women and their partners are confronted with ethical dilemmas regarding: the right to know and the right not to know; decision-making about the remainder of the pregnancy and the desire for a healthy child; responsibility for the unborn child, for its well-being and possible suffering; life and death. This book provides answers from an ethical, psychoanalytical and medical viewpoint.
Based on the highly successful first edition of Prostate Biopsy: Indications, Techniques, and Complications, this new volume presents new concepts that have emerged in answer to current questions from its audience. Many new perspectives and technologies are presented, many from the authors' internationally recognized work on the topic. Substantial developments in techniques and complications are explored in detail. The chapter authors comprise a complete spectrum of specialists in their respective subject areas. All authors are internationally accepted as the premier authorities on their chosen topics. Prostate Cancer Diagnosis: PSA, Biopsy, and Beyond presents new data on the controversial issue of PSA screening and thresholds as indication to perform biopsy. Office based transrectal saturation biopsy is covered in detail. Other topics explored include template guided biopsy and image-guided biopsy as well as a completely new paradigm for prevention of complications. Prostate Cancer Diagnosis: PSA, Biopsy, and Beyond will be of great value and utility to all practicing urologists.
The interpretation of skin lesions in children that may be due to abuse is often not straightforward, and many reports have been published on dermatological disorders and accidental injuries that were unjustly regarded as signs of child abuse. This book describes in detail the cutaneous manifestations of the physical abuse of children and devotes particular attention to differential diagnosis. Careful guidance is provided on the optimal evaluation of children presenting with findings potentially attributable to abuse. The numerous images and detailed background information will develop the ability of the reader to assess and interpret the clinical signs of abuse, and to distinguish these signs from other causes of injury, such as accidents and self-mutilation, and dermatological disorders. "Cutaneous Manifestations of Child Abuse" will be invaluable for pediatric dermatologists, pediatricians, forensic experts, and others who deal with the physical abuse of children.
This book examines in depth the evidence, clinical applications and potential cancer signatures in the circulation and discusses alterations in circulating cell-free nucleic acids, and circulating tumor DNA, as well as the epigenome, genome, transcriptome (coding and noncoding), proteome (both traditional serum proteins and proteomic profiles) and metabolome. Further, it highlights the clinical applications of circulating tumor cells for each cancer type and addresses the emerging importance of extracellular vesicular contents, including miRNA, oncogenes and drug resistant factors. As such, it offers a valuable reference guide for cancer researchers, oncologists, clinicians, surgeons, medical students, oncology nurses, diagnostic laboratories, and the pharmaceutical industry. |
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