This issue of MRI Clinics of North America focuses on Functional MRI in Oncology. Articles will include: Functional MRI techniques in oncology in the era of personalized medicine, MRI biomarkers and surrogate endpoints in oncology clinical trials, Therapy monitoring with functional MRI, Multiparametric MRI in the assessment of brain tumors, Multiparametric MRI of breast cancer, Functional MRI in chest malignancies, Multiparametric MRI in abdominal malignancies, Assessment of musculoskeletal malignancies with functional MRI, Evaluation of head and neck tumors with functional MRI, Role of multiparametric MRI in malignancies of the urogenital tract, Diffusion-weighted imaging in oncology, Functional MRI in gynecologic cancer, Assessment of angiogenesis with MRI: DCE-MRI and beyond, Imaging of tumor metabolism: MR spectroscopy, and more!

Differential Diagnosis of Autism Spectrum Disorder provides a framework for clinical considerations and best practices related to diagnosing children with autism spectrum disorder (ASD) versus commonly co-occurring conditions. Differential diagnosis is a complex process, and it is common for clinicians to observe symptom overlap between conditions. In this comprehensive text, the authors focus on the similarities and differences between ASD and a second diagnosis. Leading experts provide practical guidance in the diagnostic process for ASD versus a second condition, such as anxiety or attention deficit/hyperactivity disorder. Each chapter includes clinical case studies to provide real-world examples of how clinicians make diagnostic decisions. Ample illustrations and 'decision trees' provide a visual representation of clinical decision-making.

This issue of PET Clinics focuses on Special Techniques and Technical Advances in PET/CT Imaging. Articles will include: PET/CT Guided FNAC/Biopsy; Dual Time Point Imaging; Overview of Conventional imaging based intervention in clinical practice; Special Techniques in PET/CT in evaluating genito-urinary malignances; Special techniques in PET/CT imaging for evaluation of head and neck cancer; PET/CT enteroclysis; Contrast media in PET/CT imaging; PET/CT guided RFA; Non-attenuated corrected PET/CT imaging and applications; and more!

Continuing a legacy of excellence that spans nearly five decades, Bates' Nursing Guide to Physical Examination and History Taking, 3rd Edition, adapts the proven techniques and vibrant visuals of Bates' gold-standard assessment text specifically for the needs of today's nursing students. Thoroughly updated, evidence-based coverage emphasizes the healthy patient and clearly details common findings and diseases to help students develop and practice key skills in physical examination and history taking. Content is logically organized by Foundations, Body Systems, and Special Lifespan Considerations, incorporating essential review of anatomy and physiology, as well as critical practice in health history review, recording findings, and health promotion. Reflecting the latest research in the field, including emerging issues such as vaping, the opioid crisis, and the COVID-19 pandemic, the 3rd Edition combines trusted approaches with current clinical perspectives to equip your students for success throughout their nursing careers.

First published in 1912, French's Index of Differential Diagnosis helps clinicians in the differential diagnosis of any condition which may be seen in hospital or general practice. Arranged alphabetically by symptom, the text helps readers identify each presentation, describes the different diagnoses that it could represent, and explains the tests used to make a diagnosis. Colour clinical photographs help with diagnoses at a glance. The book is completely revised - many sections are largely rewritten, new ones added, diagnostic methods updated, many old illustrations replaced and others inserted. The emphasis, however, remains the same: the importance of a careful history, detailed clinical examination and the judicious use of laboratory and imaging investigations in the elucidation of the correct diagnosis. This reference is indispensable to medical students as well as trainee and established doctors in both general and hospital practice.

This book presents different experimental results as evidence of the good results obtained compared with respect to conventional approaches and literature references based on fuzzy logic. Nowadays, the evolution of intelligence systems for decision making has been reached considerable levels of success, as these systems are getting more intelligent and can be of great help to experts in decision making. One of the more important realms in decision making is the area of medical diagnosis, and many kinds of intelligence systems provide the expert good assistance to perform diagnosis; some of these methods are, for example, artificial neural networks (can be very powerful to find tendencies), support vector machines, that avoid overfitting problems, and statistical approaches (e.g., Bayesian). However, the present research is focused on one of the most relevant kinds of intelligent systems, which are the fuzzy systems. The main objective of the present work is the generation of fuzzy diagnosis systems that offer competitive classifiers to be applied in diagnosis systems. To generate these systems, we have proposed a methodology for the automatic design of classifiers and is focused in the Generalized Type-2 Fuzzy Logic, because the uncertainty handling can provide us with the robustness necessary to be competitive with other kinds of methods. In addition, different alternatives to the uncertainty modeling, rules-selection, and optimization have been explored. Besides, different experimental results are presented as evidence of the good results obtained when compared with respect to conventional approaches and literature references based on Fuzzy Logic.

Viral hemorrhagic fevers (VHFs) represent a collection of illnesses caused by several distinct viral families. While some types of hemorrhagic fever viruses can cause relatively mild illnesses, many of these viruses cause life-threatening diseases. The chapters of this book discuss the consequences of the Ebola outbreak in West Africa; the most frequency imported infection worldwide (malaria); the reservoirs of selected infectious diseases (often bats and fruit bats); the clinical symptoms of viral diseases and the most widely used diagnostic methods for the correct identification of the pathogen involved; and a discussion on Japanese encephalitis (JE) as an infectious disease caused by a virus transmitted by blood-sucking arthropods.

Coagulopathy (also called clotting disorder and bleeding disorder) is a condition in which the blood's ability to clot (coagulate) is impaired. Acquired hemophilia is a rare disorder characterized by spontaneous bleeding in a patient with no previous personal or family hemorrhagic history. The first chapter explores the challenges associated with this disease, its unfamiliarity often causing a delay in diagnosis and therapeutic approaches. The second chapter focuses on lower gastrointestinal bleeding (LGIB) in children, describing the epidemiology, etiology and clinical management. The third chapter reviews the pathogenesis, risk factors and treatment strategies of coagulopathy in patients with craniocerebral injury. The next article examines Vitamin B12 with its four cobalamin vitamers, which often play a role in coagulation. The next chapter starts with a description of the methodology of viscoelastic hemostatic assay, followed by a review of literature on the utilization of thrombelastography (TEG) or rotational thromboelastometry (ROTEM). Finally, the role of TEG and ROTEM to monitor or guide prophylaxis/treatment of thromboembolic events and the limitations of using them to detect hypercoagulability and identify patients with increased risks for thromboembolic complications are discussed. The final chapter of this book focuses on the use of fresh frozen plasma (FFP) in patients who are not actively bleeding, critically questions these assumptions in the context of pre-procedural administration of FFP, and also examines why carrying out high quality trails in this area has been so problematic.

Volume 70 in the internationally acclaimed Advances in Clinical Chemistry contains chapters authored by world renowned clinical laboratory scientists, physicians and research scientists. The serial provides the latest and most up-to-date technologies related to the field of clinical chemistry and is the benchmark for novel analytical approaches in the clinical laboratory.

This book highlights assessment techniques, issues, and procedures that appeal to practicing clinicians. Rather than a comprehensive handbook of various tests and measures, The Clinical Assessment of Children and Adolescents is a practitioner-friendly text that provides guidance for test selection, interpretation, and application. With topics ranging from personality assessment to behavioral assessment to the assessment of depression and thought disorder, the leaders in the field of child and adolescent measurement outline selection and interpretation of measures in a manner that is most relevant to clinicians and graduate students. Each chapter makes use of extensive case material in order to highlight issues of applicability.

Understanding Microbial Biofilms: Fundamentals to Applications focuses on the microbial biofilms of different environments. The book provides a comprehensive overview of the fundamental aspects of microbial biofilms, their existence in nature, their significance, and the different clinical and environmental problems associated with them. The book covers both the fundamentals and applications of microbial biofilms, with chapters on the introduction to the microbial community and its architecture, physiology, mechanisms and imaging of biofilms in nature and fungal, algal, and bacillus biofilm control. In addition, the book highlights the molecular and biochemical aspects of bacterial biofilms, providing a compilation of chapters on the bacterial community and communication from different environments. Finally, the book covers recent advancements in various aspects of microbial biofilms including the chapters on their biotechnological applications. All the chapters are written by experts who have been working on different aspects of microbial biofilms.

Volume 67 in the internationally acclaimed Advances in Clinical Chemistry contains chapters authored by world renowned clinical laboratory scientists, physicians and research scientists. The serial provides the latest and most up-to-date technologies related to the field of Clinical Chemistry and is the benchmark for novel analytical approaches in the clinical laboratory.

Volume64 in the internationally acclaimed "Advances in Clinical Chemistry" contains chapters authored by world renowned clinical laboratory scientists, physicians and research scientists.The serialprovides the latest and most up-to-date technologies related to the field of Clinical Chemistry andis the benchmark for novel analytical approaches in the clinical laboratory.
Expertise of international contributorsLatest cutting-edge technologiesComprehensive in scope"

Apathy is characterized by loss of motivation, decreased initiative, and emotional blunting. It is highly prevalent in neurological, and psychiatric disorders like Alzheimer's disease, traumatic brain injury, schizophrenia, Parkinson's disease, Huntington's disease, cerebrovascular disorders, and mild behavioural impairment. It has negative outcomes including impairments in activities of daily living, caregiver burden, and higher rates of institutionalization and mortality. The definition of apathy has changed over the years alongside the development of diagnostic criteria and apathy scales and measurements. Apathy is emerging as a treatment target with interest in pharmacological, non-pharmacological, and neuromodulatory treatments for apathy. There is also an increased understanding of the neurobiology of apathy with functional and structural neuroimaging research studies. This book is a comprehensive, in-depth review from experts in neurology and psychiatry. It reviews the current state of apathy in these various disorders while also summarizing apathy diagnostic criteria, scales and measurements, neuropathology, and treatments.

Degenerative Disc Disease plagues the millions of people that suffer from it. This books aims to provide the information sought out by those millions of people. Frederick Earlstein has written this medical education guide to provide an understanding of Disc Disease including medical treatments, alternative treatments and self-care, nutrition and spine health. Treatment, surgery, symptoms, exercises, causes, physical therapy, neck, back pain, and much more are all covered. The book is written in an easy to read and understandable style. In a straight forward, no nonsense fashion, Frederick Earlstein covers all aspects of Degenerative Disc Disease. The book is full of informative content and answers to your questions - including some you didn't know you had

The ability to interpret and synthesise medical data is essential for doctors, yet it is a skill which can be difficult to master. Data Interpretation Made Easy focuses on developing this skill by presenting an array of case-based themes considering interpretation of blood results, X-rays, ECGs and CT images in medicine with discussion of evidence-based practice. The concise, list-based text aids easy comprehension and images provide the much needed link from raw data to evidence-based care and management. This highly practical book is essential reading for undergraduate medical students preparing for examinations. It is also ideal for junior doctors needing a succinct guide to data interpretation for everyday use. 'Dr Neel Sharma's latest venture on data interpretation has dozens of credible clinical scenarios covering many key areas of clinical medicine. And you will certainly feel challenged, as he leaves it up to you to diagnose and devise the treatment plan.' From the Foreword by Tiago Villanueva

Written by authors representing the diverse field of clinical chemistry and diagnostics, reviews in Advances in Clinical Chemistry cover a range of cutting-eduge research ranging from basic biochemical exploration to microarray technology.
Written by authors representing the diverse field of clinical chemistry and diagnostics, reviews in Advances in Clinical Chemistry cover a range of cutting-eduge research ranging from basic biochemical exploration to microarray technology.

Diagnostic Medical Parasitology covers all aspects of human medical parasitology and provides detailed, comprehensive, relevant diagnostic methods in one volume. The new edition incorporates newly recognized parasites, discusses new and improved diagnostic methods, and covers relevant regulatory requirements and has expanded sections detailing artifact material and histological diagnosis, supplemented with color images throughout the text.

This issue of Clinics in Laboratory Medicine on the topic of Laboratory Medicine in India will be Guest Edited by Tester F. Ashavaid, PhD, FACB, CSCi, and include the following article topics: Tuberculosis; Malaria; STIs and Dengue; Visceral Leishmaniasis; Neglected Tropical Diseases; Hepatitis; HIV; Diabetes; Cardiovascular diseases; Stroke; HPV / Cervical screening; Multiple congenital anomalies; Down Syndrome/Thalessemia; Muscle dystrophy; Spinal muscular atrophy; Wilson Disease; Hemophilia; National and International Accreditation; Blood Banking regulations; Distant Testing; Clinical Trials; Medical Tourism; International Reference labs; and Diagnostics in diet.

Despite diagnosis being the key feature of a physician's clinical performance, this is the first book that deals specifically with the topic. In recent years, however, considerable interest has been shown in this area and significant developments have occurred in two main areas: a) an awareness and increasing understanding of the critical role of clinical decision making in the process of diagnosis, and of the multiple factors that impact it, and b) a similar appreciation of the role of the healthcare system in supporting clinicians in their efforts to make accurate diagnoses. Although medicine has seen major gains in knowledge and technology over the last few decades, there is a consensus that the diagnostic failure rate remains in the order of 10-15%. This book provides an overview of the major issues in this area, in particular focusing on where the diagnostic process fails, and where improvements might be made.

Selected as a Doody's Core Title for 2022! Now in a fully revised 4th Edition, Modern Epidemiology remains the gold standard text in this complex and evolving field, offering unparalleled, comprehensive coverage of the principles and methods of epidemiologic research. Featuring a new, full-color design, updated models, and a new format allowing space for margin notes, this edition continues to provide authoritative information on the methodologic issues crucial to the wide range of epidemiologic applications in public health and medicine. Reflects both the conceptual development of this evolving science and the increasing role that epidemiology plays in both public health and medicine. Features a new full-color design, new coverage of marginal structural models, new instrumental variable analysis, updated structural nested models, and more. Covers a broad range of concepts and methods, including epidemiologic measures of occurrence and effect, study designs, validity, precision, statistical interference, field methods, and causal diagrams. Includes data analysis topics such as Bayesian analysis, sensitivity analysis, and bias analysis, with an extensive overview of modern regression methods including logistic and survival regression, splines, hierarchical (multilevel) regression, propensity scores and other scoring methods, and g-estimation. Discusses special topics such as disease surveillance, ecologic studies, social epidemiology, infectious disease epidemiology, genetic and molecular epidemiology, nutritional epidemiology, environmental epidemiology, reproductive epidemiology, clinical epidemiology, and meta-analysis. Coauthored by three leading epidemiologists, with contributions from experts in a variety of epidemiologic sub-disciplines.

The ideal clinical companion for evaluating and documenting sexual violence, Atlas of Sexual Violence reflects the field's most up-to-date research and clinical practice. It reviews current practices for providing patient care to adolescent and adult victims of sexual violence, and uses diverse photographs to show variances related to race and age. Coverage of wound identification and terminology helps in accurate interpretation, documentation, and courtroom testimony. From the International Association of Forensic Nurses (IAFN) and Tara Henry, a nationally known forensic nursing expert, this book is a durable, portable guide suitable for anyone who deals with cases of suspected sexual assault, including health care providers, social workers, attorneys, and law enforcement personnel. More than 250 full-color images of normal and abnormal findings assist in determining causation and accurate identification, interpretation, and documentation of injuries. Critical information related to clinical practice is highlighted throughout the text. Interpretation of anogenital findings is simplified with coverage of normal anatomy and physiology of the mouth, genitalia, anus, and rectum, as well as anogenital variances not attributable to trauma. Unique! Postmortem Sexual Assault Examinations chapter includes the details and photos of this specific examination. Photo legends note proper identification and descriptive terminology of injuries, disease, and normal variances. Key Terms are highlighted and defined, making it easier for healthcare providers, law enforcement, and legal professionals to use accurate medical forensic terminology for documentation and courtroom testimony.

Volume 54 in the internationally acclaimed "Advances in Clinical Chemistry" contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics, ranging from basic biochemical exploration to cutting-edge microarray technology.

Leading experts from academia and clinical laboratory science
Volume emphasizes novel laboratory advances with application to clinical laboratory diagnostics and practical basic science studies

Volume 47 in the internationally acclaimed "Advances in Clinical Chemistry" contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics, ranging from basic biochemical exploration to cutting-edge microarray technology.
Leading experts from academia and clinical laboratory science Volume emphasizes novel laboratory advances with application to clinical laboratory diagnostics and practical basic science studies

Volume 47 in the internationally acclaimed "Advances in Clinical Chemistry" contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics, ranging from basic biochemical exploration to cutting-edge microarray technology.
Leading experts from academia and clinical laboratory science Volume emphasizes novel laboratory advances with application to clinical laboratory diagnostics and practical basic science studies