This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science. Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.

Catalyst production for the transformation of crudes into gasoline and other fuel products is a billion dollar/year business and fluid cracking catalysts (FCCs) represent almost half of the refinery catalyst market.
During the cracking reactions, the FCC surface is contaminated by metals (Ni, V, Fe, Cu, Na) and by coke deposition. As a result, the catalyst activity and product selectivity is reduced to unacceptable levels thus forcing refiners to replace part of the recirculating equilibrium FCC inventory with fresh FCC to compensate for losses in catalyst performance. About 1,100 tons/day of FCC are used worldwide in over 200 fluid cracking catalyst units (FCCUs).
It is for these reasons that refiners' interest in FCC research has remained high through the years almost independantly, of crude oil prices. However, recent oil company mergers and the dissolution of research laboratories, have drastically decreased the number of researchers involved in petroleum refining research projects; as a result the emphasis of research has shifted from new materials to process improvements and this trend is clearly reflected in the type of papers contained in this volume.
Modern spectroscopic techniques continue to be essential in the understanding of catalyst performance and several chapters in the book describe the use of 27Al, 29Si and 13C NMR to study variation in FCC acidity during aging and coke deposition. In addition several chapters have been dedicated to the modeling of FCC deactivation, and to the understanding of contact times on FCC performance. Refiners efforts to conform with environmental regulations are reflected in chapters dealing with sulfur removal, metalscontaminants and olefin generation.

Originally published by Bentham and now distributed by Elsevier, Recent Advances in Medicinal Chemistry, Volume 1 covers leading-edge research and recent developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies. The fourteen updated reviews include unique experimental data and references, and each article highlights an important topic in current medicinal chemistry research. Topics covered include: aureolic acid group of anti-cancer antibiotics and non-steroidal anti-inflammatory drugs; aromatase inhibitors in adjuvant endocrine treatment of early-stage breast cancer in postmenopausal women; Rho GTPases and statins in targeting and developing therapies for tumors; and more.

The indispensable reference for the twenty-first century chemist...

A fascinating and comprehensive look into one of chemistry's fastest growing specialties--sesquiterpene synthesis--Volume Ten of The Total Synthesis of Natural Products focuses on acyclic and monocyclic compounds and sheds light on the structure and makeup of this important class of hydrocarbons.

A useful and practical tool for researchers interested in locating any of the major classes of sesquiterpene compounds, the author will also provide, if needed, a database to the more than 1,600 articles on sesquiterpene synthesis. The ultimate index to the newest experimental work in synthetic chemistry, this latest volume in The Total Synthesis of Natural Products series is also a glossary to the new language of chemistry in the next century.

Look for the following related title in the series:

THE TOTAL SYNTHESIS OF NATURAL PRODUCTS, Volume Eleven

Volume Eleven continues the authoritative coverage on sesquiterpene synthesis begun in Volume Ten, examining compounds with bicyclic and tricyclic ring structures., 1997 (0-471-18874-3)

The research on the synthesis of sesquiterpenes, derivatives of terpenes, a class of hydrocarbons commonly found in oils, resins, and balsams, has grown exponentially over the past fifteen years. With over 500 sesquiterpene syntheses already developed, the literature on this experimental specialty is voluminous, now encompassing over 1,600 re-search papers. Volume Ten in The Total Synthesis of Natural Products provides a systematic and comprehensive look at acyclic and monocyclic compounds in sesquiterpene synthesis.

Reflecting one of the significant changes in sesquiterpenere-search, that is, the increase in compound targets prepared in an optically active form, the present volume includes their absolute configurations, signs of optical rotation, or both.

This newest volume in The Total Synthesis of Natural Products series is an "A-to-Z" look at acyclic and monocyclic compounds in sesquiterpene synthesis, one of the most dynamic areas in the ongoing revolution in chemical synthesis, and is a must for the chemical professional.

Natural product chemistry covers a fascinating area of organic chemistry and its study has enriched organic chemistry in a myriad of different ways. In recent years the thrust has been in three major directions: advances in stereoselective synthesis of bioactive natural products, developments in structure elucidation of complex natural products through the applications of multidimensional NMR and mass spectroscopy, and the integration of bioassay procedures with the isolation processes leading to the isolation of active principles from the extracts. The present volume reflects these developments, and the growing emphasis on bioactive natural products, chemical constituents of echinoderms, diterpenoids from Rabdosia and Eremophila sp., structural studies on saponins, marine sesquiterpene quinones and antimicrobial activity of amphibian venoms. The reviews on bioactive metabolites of Phomophis, cardenolide detection by ELISA, xenocoumacins and bioactive dihydroisocoumarins, CD studies of carbohydrate-molybdate complexes, oncogene function inhibitors from microbial secondary metabolites and Gelsemium and Lupin alkaloids present frontier developments in several areas of natural product chemistry. It is hoped that the present volume, which contains articles by eminent authorities in each field, will be received with the same enthusiasm as the previous volumes of this series.

The volumes of this classic series, now referred to simply as "Zechmeister" after its founder, Laszlo Zechmeister, have appeared under the Springer Imprint ever since the series' inauguration in 1938. The series has featured contributions by seven Nobel laureates: D.H.R. Barton, D. Crowfoot Hodgkin, L. Pauling, K. Alder, O. Diels, P. Karrer, H. von Euler-Chelpin.
The volumes contain contributions on various topics related to the origin, distribution, chemistry, synthesis, biochemistry, function or use of various classes of naturally occurring substances ranging from small molecules to biopolymers. Each contribution is written by a recognized authority in the field and provides a comprehensive and up-to-date review of the topic in question. Addressed to biologists, technologists, and chemists alike, the series can be used by the expert as a source of information and literature citations and by the non-expert as a means of orientation in a rapidly developing discipline.

Over the last decades, amino acids have been found to be of importance in many fields of science. Apart from their biological function, this family of organic compounds has been employed in the synthesis of a vast variety of salts, with impact on areas such as materials science, pharmaceutical or physical research. This covers a wide range, from the discovery of important ferroelectrics or non-linear optical materials to nutrients, flavor enhancers or drugs. This book describes amino acids and their salts with cations, anions and inorganic compounds from a chemical, physical and crystallographical point of view. Additional data on structural properties, crystal growth and the relation of structure and physical properties of amino acid salts is discussed.

Coverage in this annual review of the literature presents a comprehensive and critical survey of the vast field of study involving organophosphorus compounds, from phosphines and phosphonium salts through to phosphorus acid derivatives, nucleotides, ylides and phosphazenes. The critical reviews in this volume enable industrial and academic researchers to keep abreast of the latest developments in their specialist fields.

Class-tested and thoughtfully designed for student engagement, Principles of Organic Chemistry provides the tools and foundations needed by students in a short course or one-semester class on the subject. This book does not dilute the material or rely on rote memorization. Rather, it focuses on the underlying principles in order to make accessible the science that underpins so much of our day-to-day lives, as well as present further study and practice in medical and scientific fields. This book provides context and structure for learning the fundamental principles of organic chemistry, enabling the reader to proceed from simple to complex examples in a systematic and logical way. Utilizing clear and consistently colored figures, Principles of Organic Chemistry begins by exploring the step-by-step processes (or mechanisms) by which reactions occur to create molecular structures. It then describes some of the many ways these reactions make new compounds, examined by functional groups and corresponding common reaction mechanisms. Throughout, this book includes biochemical and pharmaceutical examples with varying degrees of difficulty, with worked answers and without, as well as advanced topics in later chapters for optional coverage.

Organic Chemistry Concepts: An EFL Approach provides an introductory overview of the subject, to enable the reader to understand many critical, experimental facts. Designed to cover a single-semester course or a needed review on the principles of Organic Chemistry, the book is written and organized for readers whose first language is not English. Approximately 80% of the words used are drawn from the list of the 2,000 most common English words; the remaining 20% includes necessary technical words, common chemistry terms, and well-known academic words (per the Academic Word List). The book has been class-tested internationally as well as with native English speakers, and differs from other introductory textbooks in the subject both in its coverage and organization, with a particular focus on common problem areas. Focused on a limited number of functional classes, Organic Chemistry Concepts: An EFL Approach introduces those organic compounds early in the book. Once readers have a foundation of the concepts and language of organic chemistry, they can build from that knowledge and work with relatively complex molecules, such as some natural product types covered in a later chapter. The book describes basic level reaction mechanisms when instructive, and illustrations throughout to emphasize the 3D nature of organic chemistry. The book includes multiple pedagogical features, such as chapter questions and useful appendices, to support reader comprehension.

"Writing Reaction Mechanisms in Organic Chemistry, Third Edition "is an invaluable guide to understanding the movements of atoms and electrons in the reactions of organic molecules. Expanding on the successful book by Miller and Solomon, this new edition further enhances your understanding of reactions. The whole book has been extensively revised with new material including a completely new chapter. To further aid understanding, all illustrations have been redrawn with the use of color to clearly indicate how each reaction works. This book illustrates that understanding organic reactions is based on applying general principles rather than memorizing unrelated processes. This approach helps you understand that writing mechanisms is a practical method of applying knowledge of previously encountered reactions and reaction conditions to new reactions. After simply explaining basic principles, this book then examines each type of reaction. A clear background and explanation is provided for each reaction, followed by an example of the reaction in use. At the end of each section is a series of problems, with a wider range of challenging questions, to test your understanding of the mechanism, with answers to check that you are right. Students and research chemists alike will find this revised book useful to organize what may seem an overwhelming quantity of information into a set of simple general principles and guidelines for determining and describing organic reaction mechanisms.
Extensively rewritten and reorganized with a completely new chapter on oxidation and reduction reactions including stereochemical reactionsEssential for those who need to have mechanisms explained in greater detail than most organic chemistry textbooks provideNow illustrated with hundreds of colorful chemical structures to help you understand reaction processes more easilyNew and extended problem sets and answers to help you understand the general principles and how to apply this to real applicationsNew information boxes throughout the text to provide useful background to reactions and the people behind the discovery of a reaction

The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.

Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area-one of great importance to organic chemists, polymer chemists and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.

Organic Chemistry Study Guide: Key Concepts, Problems, and Solutions features hundreds of problems from the companion book, Organic Chemistry, and includes solutions for every problem. Key concept summaries reinforce critical material from the primary book and enhance mastery of this complex subject. Organic chemistry is a constantly evolving field that has great relevance for all scientists, not just chemists. For chemical engineers, understanding the properties of organic molecules and how reactions occur is critically important to understanding the processes in an industrial plant. For biologists and health professionals, it is essential because nearly all of biochemistry springs from organic chemistry. Additionally, all scientists can benefit from improved critical thinking and problem-solving skills that are developed from the study of organic chemistry. Organic chemistry, like any "skill", is best learned by doing. It is difficult to learn by rote memorization, and true understanding comes only from concentrated reading, and working as many problems as possible. In fact, problem sets are the best way to ensure that concepts are not only well understood, but can also be applied to real-world problems in the work place.

Established in 1960, "Advances in Heterocyclic Chemistry" is the definitive serial in the area one of great importance to organic chemists, polymer chemists and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.
One of great importance to organic chemists, polymer chemists and many biological scientists

Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties "

Discovery of Frustrated Lewis Pairs: Intermolecular FLPs for Activation of Small Molecules, by Douglas W. Stephan Intramolecular Frustrated Lewis Pairs: Formation and Chemical Features, by Gerald Kehr, Sina Schwendemann, Gerhard Erker Frustrated Lewis Pair Mediated Hydrogenations, by Douglas W. Stephan, Gerhard Erker Amine-Borane Mediated Metal-Free Hydrogen Activation and Catalytic Hydrogenation, by Victor Sumerin, Konstantin Chernichenko, Felix Schulz, Markku Leskela, Bernhard Rieger, Timo Repo Hydrogen Activation by Frustrated Lewis Pairs: Insights from Computational Studies, by Tibor Andras Rokob, Imre Papai Quantum Chemistry of FLPs and Their Activation of Small Molecules: Methodological Aspects, by Birgitta Schirmer, Stefan Grimme Computational Design of Metal-Free Molecules for Activation of Small Molecules, Hydrogenation, and Hydroamination, by Zhi-Xiang Wang, Lili Zhao, Gang Lu, Haixia Li, Fang Huang Computational Studies of Lewis Acidity and Basicity in Frustrated Lewis Pairs, by Thomas M. Gilbert Solid-State NMR as a Spectroscopic Tool for Characterizing Phosphane - Borane Frustrated Lewis Pairs, by Thomas Wiegand, Hellmut Eckert, Stefan Grimme

Provides a high level reference source for scientists engaged in any aspect of plant research - chemistry, biochemistry or physiology - with primary focus on the chemistry of phosphorus-containing compounds that occur naturally in the plant kingdom, and specifically in the higher plants (Plantae).

The book is comprehensive with respect to nomenclature, physical properties, and distribution worldwide. There are many tables of actual data on phosphorus compounds occurring in whole plants and parts of plants. The tables provide detailed data that is needed by the food industry, agriculture, etc as many of the phosphorus compounds are common to both plants and animals.

Two appendices cover other aspects including changes in phosphorus-containing compounds during germination and their accumulation during growth and senescence. The final sections of the book comprise separate indexes of plants, compounds and authors.

Comprehensive examination of phosphorus compounds found in plants Extensive tables listing types of compounds and their occurrence in plants including: Nomenclature; Occurrence; Physical Properties; Synthesis; Hydrolysis; Phosphorylation; Extraction; Separation and Analysis; Easy to use indexes of plants, compounds and authors"

Biocidal polymers are designed to inhibit or kill microorganisms such as bacteria, fungi and protozoans. This book summarizes recent findings in the synthesis, modification and characterization of various antimicrobial polymers ranging from plastics and elastomers to biomimetic and biodegradable polymers. Modifications with different antimicrobial agents as well as antimicrobial testing methods are described in a comprehensive manner.

Published continuously since 1944, the "Advances in Protein Chemistry and Structural Biology" serial has been a continuous, essential resource for protein chemists. Covering reviews of methodology and research in all aspects of protein chemistry, including purification/expression, proteomics, modeling and structural determination and design, each volume brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics.

Coversreviews of methodology and research in all aspects of protein chemistry. Brings forth new information about protocols and analysis of proteins while presentingthe most recent findings from leading experts in a broad range of protein-related topics. "

Established in 1960, "Advances in Heterocyclic Chemistry" is the definitive serial in the area one of great importance to organic chemists, polymer chemists and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.
Provides up-to-date material on a fast-growing and highly topical subject area
Contains the latest research covering a wide variety of heterocyclic topics
Written by leading authorities and designed as a handbook for students and industry and academic researchers"