Organophosphorus Chemistry provides a comprehensive annual review of the literature. Coverage includes phosphines and their chalcogenides, phosphonium salts, low coordination number phosphorus compounds, penta- and hexa-coordinated compounds, tervalent phosphorus acids, nucleotides and nucleic acids, ylides and related compounds, and phosphazenes. The series will be of value to research workers in universities, government and industrial research organisations, whose work involves the use of organophosphorus compounds. It provides a concise but comprehensive survey of a vast field of study with a wide variety of applications, enabling the reader to rapidly keep abreast of the latest developments in their specialist areas. Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.

This book highlights the symmetrical characteristics of organic molecules. It demonstrates how to use principles of symmetry to synthesize and prepare both symmetrical and asymmetrical molecules.

The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.

Excited States and Photochemistry of Organic Molecules Martin Klessinger Josef Michl This book provides a non-mathematical introduction to electronic excitation in organic molecules, and offers an integrated view of the principles of electronic spectroscopy, photophysics, and photochemistry. This is the first book to incorporate recent advances in understanding the role of conical intersections in photochemical and photophysical processes. Throughout the book, the concepts of potential energy surfaces, bonding theory, and molecular electronic structure in the understanding of photochemistry are emphasized. Simple and intuitive qualitative models for the nature of electronic states are used to explain how electronic structure can be probed by spectroscopy with ordinary and polarized light, including natural and magnetic circular dichroism. Every chapter includes worked examples that illustrate practical applications of theory, as well as extensive references to the original literature. Excited States and Photochemistry of Organic Molecules is suitable for use as a text for graduate and advanced undergraduate students in physical organic chemistry and photochemistry. Also available from VCH Circular Dichroism Principles and Applications K. Nakanishi, N. Berova, and R.W. Woody, eds. Hardcover. ISBN 1-56081-618-X Infrared and Raman Spectroscopy Methods and Applications B. Schrader, ed. Hardcover. ISBN 3-527-26446-9 Spectroscopy with Polarized Light Solute Alignment by Photoselection, in Liquid Crystals, Polymers, and Membranes J. Michl and E.W. Thulstrup Paperback. ISBN 1-56081-910-3

Carbohydrate Chemistry provides review coverage of all publications relevant to the chemistry of monosaccharides and oligosaccharides in a given year. The amount of research in this field appearing in the organic chemical literature is increasing because of the enhanced importance of the subject, especially in areas of medicinal chemistry and biology. In no part of the field is this more apparent than in the synthesis of oligosaccharides required by scientists working in glycobiology. Clycomedicinal chemistry and its reliance on carbohydrate synthesis is now very well established, for example, by the preparation of specific carbohydrate- based antigens, especially cancer-specific oligosaccharides and glycoconjugates. Coverage of topics such as nucleosides, amino-sugars, alditols and cyclitols also covers much research of relevance to biological and medicinal chemistry. Each volume of the series brings together references to all published work in given areas of the subject and serves as a comprehensive database for the active research chemist Specialist Periodical Reports provide systematic and detailed review coverage in major areas of chemical research. Compiled by teams of leading authorities in the relevant subject areas, the series creates a unique service for the active research chemist, with regular, in-depth accounts of progress in particular fields of chemistry. Subject coverage within different volumes of a given title is similar and publication is on an annual or biennial basis.

Discovery of Frustrated Lewis Pairs: Intermolecular FLPs for Activation of Small Molecules, by Douglas W. Stephan Intramolecular Frustrated Lewis Pairs: Formation and Chemical Features, by Gerald Kehr, Sina Schwendemann, Gerhard Erker Frustrated Lewis Pair Mediated Hydrogenations, by Douglas W. Stephan, Gerhard Erker Amine-Borane Mediated Metal-Free Hydrogen Activation and Catalytic Hydrogenation, by Victor Sumerin, Konstantin Chernichenko, Felix Schulz, Markku Leskela, Bernhard Rieger, Timo Repo Hydrogen Activation by Frustrated Lewis Pairs: Insights from Computational Studies, by Tibor Andras Rokob, Imre Papai Quantum Chemistry of FLPs and Their Activation of Small Molecules: Methodological Aspects, by Birgitta Schirmer, Stefan Grimme Computational Design of Metal-Free Molecules for Activation of Small Molecules, Hydrogenation, and Hydroamination, by Zhi-Xiang Wang, Lili Zhao, Gang Lu, Haixia Li, Fang Huang Computational Studies of Lewis Acidity and Basicity in Frustrated Lewis Pairs, by Thomas M. Gilbert Solid-State NMR as a Spectroscopic Tool for Characterizing Phosphane - Borane Frustrated Lewis Pairs, by Thomas Wiegand, Hellmut Eckert, Stefan Grimme

Provides a high level reference source for scientists engaged in any aspect of plant research - chemistry, biochemistry or physiology - with primary focus on the chemistry of phosphorus-containing compounds that occur naturally in the plant kingdom, and specifically in the higher plants (Plantae).

The book is comprehensive with respect to nomenclature, physical properties, and distribution worldwide. There are many tables of actual data on phosphorus compounds occurring in whole plants and parts of plants. The tables provide detailed data that is needed by the food industry, agriculture, etc as many of the phosphorus compounds are common to both plants and animals.

Two appendices cover other aspects including changes in phosphorus-containing compounds during germination and their accumulation during growth and senescence. The final sections of the book comprise separate indexes of plants, compounds and authors.

Comprehensive examination of phosphorus compounds found in plants Extensive tables listing types of compounds and their occurrence in plants including: Nomenclature; Occurrence; Physical Properties; Synthesis; Hydrolysis; Phosphorylation; Extraction; Separation and Analysis; Easy to use indexes of plants, compounds and authors"

"Advances in Physical Organic Chemistry" provides the chemical community with authoritative and critical assessments of the many aspects of physical organic chemistry. The field is a rapidly developing one, with results and methodologies finding application from biology to solid-state physics.
Reviews the application of quantitative and mathematical methods toward understanding chemical problemsCovers organic, organometallic, bioorganic, enzymes and materials topics

This anthological description of the history and applications of photochemistry provides photochemistry practitioners with complementary information about the field, currently not covered in existing textbooks and handbooks. The first part focuses on the historical development of the field, including light-matter interaction, the discovery of photochemical reactions and the development of modern photochemical mechanisms. This section provides useful background to the second part which outlines applications of photochemistry in the present day, such as in synthesis, green chemistry, diagnostics, medicine and nanotechnology. Furthermore, the author provides an outlook on promising areas for future developments. The broad scope of "Photochemistry: Past, Present and Future" is also of interest to the wider chemical audience and it makes a pleasant read while not compromising on scientific rigor.

Published continuously since 1944, the "Advances in Protein Chemistry and Structural Biology" serial has been a continuous, essential resource for protein chemists. Covering reviews of methodology and research in all aspects of protein chemistry, including purification/expression, proteomics, modeling and structural determination and design, each volume brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics.

Coversreviews of methodology and research in all aspects of protein chemistry. Brings forth new information about protocols and analysis of proteins while presentingthe most recent findings from leading experts in a broad range of protein-related topics. "

Since the industrial revolution, chlorine remains an iconic molecule even though its production by the electrolysis of sodium chloride is extremely energy intensive. The rationale behind this book is to present useful and industrially relevant examples for alternatives to chlorine in synthesis. This multi-authored volume presents numerous contributions from an international spectrum of authors that demonstrate how to facilitate the development of industrially relevant and implementable breakthrough technologies. This volume will interest individuals working in organic synthesis in industry and academia who are working in Green Chemistry and Sustainable Technologies.

Updated every five years, the series represents the optimal compromise between currency and a sufficient body of material for cohesive and comprehensive treatment in a monograph. Provides a quick yet thorough overview of the synthetic routines that have been used to access specific classes of therapeutic agents. Materials are organized by chemical class, and syntheses are taken back to available starting materials. Discusses disease state, rational for method of drug therapy, biological activities of each compound and preparation. Coverage also includes those generic pharmaceutical compounds not accorded clinical status. A glossary defines biological terms.

Packed with reviews plus new results from the author's laboratories, the first-of-its-kind work offers a timely and authoritative treatise on the use of mass spectral techniques in organic stereochemistry.
Featuring 22 chapters contributed by eminent and active researchers in the field, this unique sourcebook offers comparative information on the use of a variety of mass-spectral techniques to characterize stereoisomers and conformers of both large and small biologically important organic molecules. It also discusses techniques for studying gas-phase conformational equilibria in conformationally mobil systems.
Applications of Mass Spectrometry to Organic Stereochemistry will dramatically aid the lab applications of organic, biological, pharmaceutical, and analytical chemists in university and industrial laboratories.

This exhaustive work in three volumes with featuring cross-reference system provides a thorough overview of ultra-high temperature materials - from elements and chemical compounds to alloys and composites. Topics included are physical (crystallographic, thermodynamic, thermo-physical, electrical, optical, physico-mechanical, nuclear) and chemical (solid-state diffusion, interaction with chemical elements and compounds, interaction with gases, vapours and aqueous solutions) properties of the individual physico-chemical phases and multi-phase materials with melting (or sublimation) points over or about 2500 DegreesC. The first volume focuses on carbon (graphite/graphene) and refractory metals (W, Re, Os, Ta, Mo, Nb, Ir). The second and third volumes are dedicated solely to refractory (ceramic) compounds (oxides, nitrides, carbides, borides, silicides) and to the complex materials - refractory alloys, carbon and ceramic composites, respectively. It will be of interest to researchers, engineers, postgraduate, graduate and undergraduate students in various disciplines alike. The reader is provided with the full qualitative and quantitative assessment for the materials, which could be applied in various engineering devices and environmental conditions at ultra-high temperatures, on the basis of the latest updates in the field of physics, chemistry, materials science, nanotechnology and engineering.

The series Topics in Current Chemistry presents critical reviews of the present and future trends in modern chemical research. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field. Review articles for the individual volumes are invited by the volume editors. Readership: research chemists at universities or in industry, graduate students

This volume deals with the chemistry of five-membered heterocycles containing at least two nitrogen atoms, or those with one, or more, nitrogens and one or more atoms from group 6 of the Peri tables. It includes chapters on: oxadiazoles and thiadiazoles; five-memebered heterocyclic compounds with four-heter-atoms in the ring; five-membered rings containing two nitrogen atoms; and five-membered heterocyclic compounds with three hetero-atoms in the ring.

Established in 1960, "Advances in Heterocyclic Chemistry" is the definitive serial in the area one of great importance to organic chemists, polymer chemists and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.
Provides up-to-date material on a fast-growing and highly topical subject area
Contains the latest research covering a wide variety of heterocyclic topics
Written by leading authorities and designed as a handbook for students and industry and academic researchers"

Find out how theoretical calculations are used to determine, elucidate and propose mechanisms for Pd-catalyzed C-C cross-coupling reactions in Max Garcia Melchor's outstanding thesis. Garcia Melchor investigates one of the most significant and useful types of reactions in modern organic synthesis; the Pd-cross coupling reaction. Due to its versatility, broad scope and selectivity under mild conditions, this type of reaction can now be applied in fields as diverse as the agrochemical and pharmaceutical industry. Garcia Melchor studies the reaction intermediates and transition states involved in the Negishi, the copper-free Sonogashira and the asymmetric version of Suzuki-Miyaura coupling. He also characterizes and provides a detailed picture of the associated reaction mechanisms. The author has won numerous prizes for this work which has led to over eight publications in internationally renowned journals.

Established in 1960, "Advances in Heterocyclic Chemistry" is the definitive serial in the area one of great importance to organic chemists, polymer chemists and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.
Provides up-to-date material on a fast-growing and highly topical subject area
Contains the latest research covering a wide variety of heterocyclic topics
Written by leading authorities and designed as a handbook for students and industry and academic researchers"

Based on presentations made during the 6th International Symposium on Natural Product Chemistry, this book is divided into two broad sections. Section A includes articles on synthetic routes developed to complex natural products, while Section B is a compilation of discoveries of new natural products and their pharmacological properties.
There are several chapters devoted to various advances in the ongoing quest for improved anticancer agents from natural sources, be they from plants, marine organisms or microorganisms. Approaches to the development of new antimalarial agents are reviewed, as are strategies for cancer chemopreventive agents.

This volume contains a survey of 51 ring systems in which an imidazole ring is fused to an additional five-membered ring system. Ring systems included are those appearing in the Chemical Abstracts Index of Ring Systems under the 2-ring 5-5 citation and including a C3N2 fragment. The material is subsequently subdivided into chapters based on the number and types of hetero atoms in the additional 5-membered ring. The synthesis, physiochemical properties and reactions of compounds in each ring system are covered; reactions are organized on a mechanistic basis and the survey includes compounds that are both partially and fully saturated.

The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects - properties, synthesis, reactions, physiological and industrial significance - of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.

Provides a synthetic armory of tools to aid the practicing chemist by reviewing the most reliable historical methods alongside new methods/ Written by scientists who have actually used these in synthesis. By emphasizing tricks and tips to optimize reactions for the best yields and purity, which are often missing from the primary literature, this book provides another dimension for the synthetic chemist. A combined academic and industrial approach evaluates the best methods for different scales of reaction and discusses practical tips (e.g. when to stop a reaction early to maximize purity or when to re-use side products). Chapters also assess whether to make or source starting materials, how to connect them and what are the best synthetic routes. The book is designed to be a stand-alone reference, but also provides cross references to leading reviews and the "Comprehensive Heterocyclic Chemistry" reference works for those who want to learn more.
Reviews tried and tested practical methods to help the reader select the best method for their researchIncludes tips, tricks and hints to enable the reader to get the best yield or cleanest product out of their reaction for synthesising or transforming a pyridine derivativeWritten by both academic researchers and industry leaders this provides a unique view of how to get the most out of a reaction no matter what scale you are running this on