This book will cover the full scope of nanobiosensing, which combines the newest research results in the cross-disciplines of chemistry, biology, and materials science with biosensing and bioanalysis to develop novel detection principles, sensing mechanisms, and device engineering methods. It not only covers the important types of nanomaterials for biosensing applications, including carbon nanotubes, carbon nanofiber, quantum dots, fullerenes, fluorescent and biological molecules, etc., but also illustrates a wide range of sensing principles, including electrochemical detection, fluorescence, chemiluminesence, antibody-antigen interactions, and magnetic detection. The book details novel developments in the methodology and devices of biosensing and bioanalysis combined with nanoscience and nanotechnology, as well as their applications in biomedicine and environmental monitoring. Furthermore, the reported works on the application and biofunction of nanoparticles have attracted extensive attention and interest, thus they are of particular interest to readers. The reader will obtain a rich survey of nanobiosensing technology, including the principles and application of biosensing, the design and biofunctionalization of bionanomaterials, as well as the methodology to develop biosensing devices and bioanalytical systems.

Quantum dots as nanomaterials have been extensively investigated in the past several decades from growth to characterization to applications. As the basis of future developments in the field, this book collects a series of state-of-the-art chapters on the current status of quantum dot devices and how these devices take advantage of quantum features. Written by 56 leading experts from 14 countries, the chapters cover numerous quantum dot applications, including lasers, LEDs, detectors, amplifiers, switches, transistors, and solar cells. Quantum Dot Devices is appropriate for researchers of all levels of experience with an interest in epitaxial and/or colloidal quantum dots. It provides the beginner with the necessary overview of this exciting field and those more experienced with a comprehensive reference source.

Due to their rare combination of high chemical stability, exceptional optical and electrical properties, high surface-to-volume ratio, and high aspect ratio, carbon nanotubes (CNTs) have made an enormous impact on materials science, molecular biology, biomedicine, and bioanalytical chemistry. Carbon Nanotubes: Methods and Protocols provides reliable, consistent protocols on the application of CNTs in molecular biology-related fields. These are of vital importance, as the commercially available CNTs differ in purity, agglomeration state, as well as length and diameter distribution, all of which have a profound influence on the dispersability and surface properties of the tubes. The volume contains detailed sections on functionalization, toxicity, trafficking, scaffolds, and biosensors, provided by expert researchers from various fields. Written in the highly successful Methods in Molecular Biology (TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Carbon Nanotubes: Methods and Protocols serves to contribute to the achievement of common standards and helps researchers to avoid discrepancies in future biology-related CNT studies.

This book covers a wide range of topics relating to carbon nanomaterials, from synthesis and functionalization to applications in advanced biomedical devices and systems. As they possess unique and attractive chemical, physical, optical, and even magnetic properties for various applications, considerable effort has been made to employ carbon nanomaterials (e.g., fullerenes, carbon nanotubes, graphene, nanodiamond) as new materials for the development of novel biomedical tools, such as diagnostic sensors, imaging agents, and drug/gene delivery systems for both diagnostics and clinical treatment. Tremendous progress has been made and the scattered literature continues to grow rapidly. With chapters by world-renowned experts providing an overview of the state of the science as well as an understanding of the challenges that lie ahead, Carbon Nanomaterials for Biomedical Applications is essential reading not only for experienced scientists and engineers in biomedical and nanomaterials areas, but also for graduate students and advanced undergraduates in materials science and engineering, chemistry, and biology.

This book offers readers cutting-edge research at the interface of polymer science and engineering, biomedical engineering, materials science, and biology. State-of-the-art developments in microscale technologies for cell engineering applications are covered, including technologies relevant to both pluripotent and adult stem cells, the immune system, and somatic cells of the animal and human origin. This book bridges the gap in the understanding of engineering biology at multiple length scale, including microenvironmental control, bioprocessing, and tissue engineering in the areas of cardiac, cartilage, skeletal, and vascular tissues, among others. This book also discusses unique, emerging areas of micropatterning and three-dimensional printing models of cellular engineering, and contributes to the better understanding of the role of biophysical factors in determining the cell fate. Microscale Technologies for Cell Engineering is valuable for bioengineers, biomaterial scientists, tissue engineers, clinicians, immunoengineers, immunologists and stem cell biologists, as it offers a review of the current cutting-edge cell engineering research at multiple length scale and will be valuable in developing new strategies for efficient scale-up and clinical translation.

This book presents a new approach to modeling carbon structures such as graphene and carbon nanotubes using finite element methods, and addresses the latest advances in numerical studies for these materials. Based on the available findings, the book develops an effective finite element approach for modeling the structure and the deformation of grapheme-based materials. Further, modeling processing for single-walled and multi-walled carbon nanotubes is demonstrated in detail.

This book focuses on the modeling and analysis of heat and fluid flow in microchannels and micro-systems, compiling a number of analytical and hybrid numerical-analytical solutions for models that account for the relevant micro-scale effects, with the corresponding experimental analysis validation when applicable. The volume stands as the only available compilation of easy to use analytically-based solutions for micro-scale heat and fluid flow problems, that systematically incorporates the most relevant micro-scale effects into the mathematical models, followed by their physical interpretation on the micro-system behavior.

This book brings together papers from all spheres of mechanical engineering related to gears and transmissions, from fundamentals to advanced applications, from academic results in numerical and experimental research, to new approaches to gear design and aspects of their optimization synthesis and to the latest developments in manufacturing. Furthermore, this volume honours the work of Faydor L. Litvin on the 100th anniversary of this birth. He is acknowledged as the founder of the modern theory of gearing. An exhaustive list of his contributions and achievements and a biography are included.

The release of this second volume of CHIPS 2020 coincides with the 50th anniversary of Moore's Law, a critical year marked by the end of the nanometer roadmap and by a significantly reduced annual rise in chip performance. At the same time, we are witnessing a data explosion in the Internet, which is consuming 40% more electrical power every year, leading to fears of a major blackout of the Internet by 2020. The messages of the first CHIPS 2020, published in 2012, concerned the realization of quantum steps for improving the energy efficiency of all chip functions. With this second volume, we review these messages and amplify upon the most promising directions: ultra-low-voltage electronics, nanoscale monolithic 3D integration, relevant-data, brain- and human-vision-inspired processing, and energy harvesting for chip autonomy. The team of authors, enlarged by more world leaders in low-power, monolithic 3D, video, and Silicon brains, presents new vistas in nanoelectronics, promising Moore-like exponential growth sustainable through to the 2030s.

This volume contains papers that have been selected after review for oral presentation at ISRM 2015, the Fourth IFToMM International Symposium on Robotics and Mechatronics held in Poitiers, France 23-24 June 2015. These papers provide a vision of the evolution of the disciplines of robotics and mechatronics, including but not limited to: mechanism design; modeling and simulation; kinematics and dynamics of multibody systems; control methods; navigation and motion planning; sensors and actuators; bio-robotics; micro/nano-robotics; complex robotic systems; walking machines, humanoids-parallel kinematic structures: analysis and synthesis; smart devices; new design; application and prototypes. The book can be used by researchers and engineers in the relevant areas of robotics and mechatronics.

This book explores emerging methods and algorithms that enable precise control of micro-/nano-positioning systems. The text describes three control strategies: hysteresis-model-based feedforward control and hysteresis-model-free feedback control based on and free from state observation. Each paradigm receives dedicated attention within a particular part of the text. Readers are shown how to design, validate and apply a variety of new control approaches in micromanipulation: hysteresis modelling, discrete-time sliding-mode control and model-reference adaptive control. Experimental results are provided throughout and build up to a detailed treatment of practical applications in the fourth part of the book. The applications focus on control of piezoelectric grippers. Advanced Control of Piezoelectric Micro-/Nano-Positioning Systems will assist academic researchers and practising control and mechatronics engineers interested in suppressing sources of nonlinearity such as hysteresis and drift when combining position and force control of precision systems with piezoelectric actuation.

This book is the first comprehensive collection of electronic aspects of different kinds of elastomer composites, including combinations of synthetic, natural and thermoplastic elastomers with different conducting fillers like metal nanoparticles, carbon nanotubes, or graphenes, and many more. It covers elastomer composites, which are useful in electronic applications, including chemical and physical as well as material science aspects. The presented elastomer composites have great potential for solving emerging new material application requirements, for example as flexible and wearable electronics. The book is structured and organized by the rubber/elastomer type: each chapter describes a different elastomer matrix and its composites. While introducing to important fundamentals, it is application-oriented, discussing the current issues and challenges in the field of elastomer composites. This book will thus appeal to researchers and scientists, to engineers and technologists, but also to graduate students, working on elastomer composites, or on electronics engineering with the composites, providing the readers with a sound introduction to the field and solutions to both fundamental and applied problems.

This work describes theoretical and experimental advances towards the realization of a hybrid quantum processor in which the collective degrees of freedom of an ensemble of spins in a crystal are used as a multi-qubit register for superconducting qubits. A memory protocol made of write, read and reset operations is first presented, followed by the demonstration of building blocks of its implementation with NV center spins in diamond. Qubit states are written by resonant absorption of a microwave photon in the spin ensemble and read out of the memory on-demand by applying Hahn echo refocusing techniques to the spins. The reset step is implemented in between two successive write-read sequences using optical repumping of the spins.

This book considers the design and development of nanoelectronic computing circuits, systems and architectures focusing particularly on memristors, which represent one of today's latest technology breakthroughs in nanoelectronics. The book studies, explores, and addresses the related challenges and proposes solutions for the smooth transition from conventional circuit technologies to emerging computing memristive nanotechnologies. Its content spans from fundamental device modeling to emerging storage system architectures and novel circuit design methodologies, targeting advanced non-conventional analog/digital massively parallel computational structures. Several new results on memristor modeling, memristive interconnections, logic circuit design, memory circuit architectures, computer arithmetic systems, simulation software tools, and applications of memristors in computing are presented. High-density memristive data storage combined with memristive circuit-design paradigms and computational tools applied to solve NP-hard artificial intelligence problems, as well as memristive arithmetic-logic units, certainly pave the way for a very promising memristive era in future electronic systems. Furthermore, these graph-based NP-hard problems are solved on memristive networks, and coupled with Cellular Automata (CA)-inspired computational schemes that enable computation within memory. All chapters are written in an accessible manner and are lavishly illustrated. The book constitutes an informative cornerstone for young scientists and a comprehensive reference to the experienced reader, hoping to stimulate further research on memristive devices, circuits, and systems.

This book provides a broad overview on the relationship between structure and mechanical properties of carbon nanomaterials from world-leading scientists in the field. The main aim is to get an in-depth understanding of the broad range of mechanical properties of carbon materials based on their unique nanostructure and on defects of several types and at different length scales. Besides experimental work mainly based on the use of (in-situ) Raman and X-ray scattering and on nanoindentation, the book also covers some aspects of multiscale modeling of the mechanics of carbon nanomaterials.

This book presents the most advanced review available of all aspects of -electron systems, including novel structures, new synthetic protocols, chemical and physical properties, spectroscopic and computational insights, molecular engineering, device properties and physiological properties. -Electron systems are ubiquitous in nature. Plants convert light energy into chemical energy by photosynthetic processes, in which chlorophylls and other porphyrinoids play an important role. On the one hand, research to learn about photosynthesis from nature has led to understanding of electron and energy transfer processes and to achieving artificial energy conversion systems inspired by nature. On the other hand, recent advances in organic and inorganic chemistry make it possible to construct novel -electron systems that had never existed in nature. The authors of this book are from a variety of research fields including organic chemistry, inorganic chemistry, physical chemistry, materials science, and biology, providing a comprehensive overview of -electron systems for a broad readership. Not only specialists but also graduate students working in -electron systems will find the book of great interest. Throughout, the diverse potential for future fruitful applications of -electron systems is revealed to the reader.

The 16thInternational Symposium on MEMS and Nanotechnology, Volume 5 of the Proceedings of the 2015SEM Annual Conference& Exposition on Experimental and Applied Mechanics, the fifth volume of nine from the Conference, brings together contributions to this important area of research and engineering. The collection presents early findings and case studies on a wide range of areas, including: Microscale and Microstructural Effects on Mechanical Behavior Dynamic Micro/Nanomechanics In-situ Techniques Mechanics of Graphene Indentation and Small Scale Testing MEMS

This book presents the physical and technical foundation of the state of the art in applied scanning probe techniques. It constitutes a timely and comprehensive overview of SPM applications. The chapters in this volume relate to scanning probe microscopy techniques, characterization of various materials and structures and typical industrial applications, including topographic and dynamical surface studies of thin-film semiconductors, polymers, paper, ceramics, and magnetic and biological materials. The chapters are written by leading researchers and application scientists from all over the world and from various industries to provide a broader perspective.

The technologies for product assembly and manufacturing evolve along with the advancement of enabling technologies such as material science, robotics, machine intelligence as well as information and communication. Furthermore, they may be subject to fundamental changes due to the shift in key product features and/or - gineering requirements. The enabling technologies emerging offer new opportunities for moving up the level of automation, optimization and reliability in product assembly and ma- facturing beyond what have been possible. We see assembly and manufacturing becoming more Intelligent with the perception-driven robotic autonomy, more flexible with the human-robot coupled collaboration in work cells, and more in- grated in scale and complexity under the distributed and networked frameworks. On the other hand, the shift in key product features and engineering requirements dictates the new technologies and tools for assembly and manufacturing to be - veloped. This may be exemplified by a high complexity of micro/nano system products integrated and packaged in 3D with various heterogeneous parts, com- nents, and interconnections, including electrical, optical, mechanical as well as fluidic means.

Now back in print, this life of George Eastman is the first biography since 1930 of the man who transformed the world of photography. In this revealing and informative work, Brayer shows us how such key innovations as roll film and the light, hand-held camera helped the Eastman Kodak Company dominate the world market. More importantly, Brayer draws a vivid portrait of the man behind the money. Eastman worked hard at staying out of the limelight and even insisted that his donations be kept anonymous, prompting the Boston Globe to call him "America's most modest and least-known millionaire." Despite his retirement in 1925, Eastman showed little sign of slowing down. Making money had been interesting, but putting money to work became more so. In the 1920s he designed a special camera for use in orthodontia and established elaborate dental clinics for needy children around the world. He oversaw the building of the Eastman theatre and the Eastman School of Music. His contributions built a new campus for the Massachusetts Institute of Technology and a new medical school for the University of Rochester. Finally, he became the largest contributor to the education of African Americans during the 1920s and the Tuskegee Institute's most important benefactor. Elizabeth Brayer lives in Rochester, NY. For the past 18 years she has served on both the George Eastman Legacy and the Landscape committees at the George Eastman House, International Museum of Photography and Film. She writes about the history of central and Western New York State. George Eastman: A Biography was nominated for a Pulitzer Prize in 1996.

This book describes the latest efforts to develop aluminum nanocomposites with enhanced damping and mechanical properties and good workability. The nanocomposites exhibited high strength, improved damping behavior and good ductility, making them suitable for use as wires. Since the production of metal matrix nanocomposites by conventional melting processes is considered extremely problematic (because of the poor wettability of the nanoparticles), different powder metallurgy routes were investigated, including high-energy ball milling and unconventional compaction methods. Special attention was paid to the structural characterization at the micro- and nanoscale, as uniform nanoparticle dispersion in metal matrix is of prime importance. The aluminum nanocomposites displayed an ultrafine microstructure reinforced with alumina nanoparticles produced in situ or added ex situ. The physical, mechanical and functional characteristics of the materials produced were evaluated using different mechanical tests and microstructure investigation techniques. The book presents and discusses the experimental results in detail, and offers suggestions for future research directions.

This book presents cutting-edge research on a wide range of nanotechnology techniques and applications. It features contributions from scientists who participated in the International Summer School "Nanotechnology: From Fundamental Research to Innovations" in Bukovel, Ukraine on August 26 - September 2, 2012 funded by the European Commission FP7 project Nanotwinning implemented by the Institute of Physics of National Academy of Sciences of Ukraine and partner institutions: University of Tartu (Estonia), European Profiles A.E. (Greece), University of Turin (Italy) and Universite Pierre et Marie Curie (France). Worldwide experts present the latest results on such key topics as microscopy of nanostructures; nanocomposites; nanostructured interfaces and surfaces; nanooptics; nanoplasmonics; and enhanced vibrational spectroscopy. Imaging technique coverage ranges from atomic force microscopy and spectroscopy, multiphoton imagery, and laser diagnostics of nanomaterials and nanostructures, to resonance Raman and SERS for surface characterization, and scanning tunneling microscopy of organic molecules. The breadth of topics highlights the exciting variety of research currently being undertaken in this field and suggests new opportunities for interdisciplinary collaboration and future research.

This book contains a selection of papers presented at the First National Conference on Sensors held in Rome 15-17 February 2011. The conference highlighted state-of-the-art results from both theoretical and applied research in the field of sensors and related technologies. This book presents material in an interdisciplinary approach, covering many aspects of the disciplines related to sensors, including physics, chemistry, materials science, biology and applications. * Provides a selection of the best papers from the First Italian National Conference on Sensors; * Covers a broad range of topics relating to sensors and microsystems, including physics, chemistry, materials science, biology and applications; * Offers interdisciplinary coverage, aimed at defining a common ground for sensors beyond the specific differences among the different particular implementation of sensors.

Polycrystalline SiGe has emerged as a promising MEMS (Microelectromechanical Systems) structural material since it provides the desired mechanical properties at lower temperatures compared to poly-Si, allowing the direct post-processing on top of CMOS. This CMOS-MEMS monolithic integration can lead to more compact MEMS with improved performance. The potential of poly-SiGe for MEMS above-aluminum-backend CMOS integration has already been demonstrated. However, aggressive interconnect scaling has led to the replacement of the traditional aluminum metallization by copper (Cu) metallization, due to its lower resistivity and improved reliability. Poly-SiGe for MEMS-above-CMOS sensors demonstrates the compatibility of poly-SiGe with post-processing above the advanced CMOS technology nodes through the successful fabrication of an integrated poly-SiGe piezoresistive pressure sensor, directly fabricated above 0.13 m Cu-backend CMOS. Furthermore, this book presents the first detailed investigation on the influence of deposition conditions, germanium content and doping concentration on the electrical and piezoresistive properties of boron-doped poly-SiGe. The development of a CMOS-compatible process flow, with special attention to the sealing method, is also described. Piezoresistive pressure sensors with different areas and piezoresistor designs were fabricated and tested. Together with the piezoresistive pressure sensors, also functional capacitive pressure sensors were successfully fabricated on the same wafer, proving the versatility of poly-SiGe for MEMS sensor applications. Finally, a detailed analysis of the MEMS processing impact on the underlying CMOS circuit is also presented.

The development of nanomaterials opens the possibility for new materials with outstanding properties compared to classical engineering materials. These materials can find applications in different fields such as medical treatment or structural mechanics. This monograph focuses on two major groups of nanomaterials, i.e.nanoparticels and nanocomposites. Nanopartices, for example in the form of hollow particles, allow for new possibilities in drug delivery. Different aspects of nanoparticles ranging from manufacturing to modeling and simulation are covered. Nanocomposite materials are formed by mixing two or more dissimilar materials at the nanoscale in order to control and develop new and improved structures and properties. The properties of nanocomposites depend not only on the individual components used but also on the morphology and the interfacial characteristics. Nanocomposite coatings and materials are one of the most exciting and fastest growing areas of research and novel properties being continuously developed which are previously unknown in the constituent materials. Thus, the second part of this monograph gives an overview on the latest developments in the area of composites and coatings based on nanomaterials.