Immunotherapy of Cancer, Volume 143, the latest release in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research. Contributions from leading experts in the field make this a must have update on the topic.

Advances in Genetics, Volume 104, provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing future directions.

The book entitled 'Rejuvenation in Fruit Trees (Tropical and Subtropical)' is up-to-date and informative, publication, covering all vital aspects on rejuvenation technology in perennial fruit trees. The book is full-fledged and updated publication on rejuvenation technology. By going through the book one can adopt this technology in all high-value fruit crops of woody perennial nature of tropical and subtropical groups. The concept of rejuvenation, present trend and constraints, its need, adoption level and successful implementation with proper package of cultural practices and management strategies, have been discussed in details in the book. All efforts have been made to increase production, productivity and profitability of fruit crops at a sustainable basis. The requisite information and need-based requirements have also been brought within purview in addition to critical perspective that foster a better understanding of its R&D issues. This book will be of immense utility to students of Agriculture/Horticulture, at B.Sc, M.Sc. and Ph.D. levels, academic experts, researchers, scientists, administrators, policy-makers, farmers, exporters, entrepreneurs and other stakeholders in fruit production enterprise.

Cognitive Archeology, Body Cognition, and the Evolution of Visuospatial Perception offers comprehensive perspective on the role of brain form and function, body cognition, and visuospatial integration in the evolution of ancient and modern human species. The book covers evolutionary neuroanatomy, cognitive sciences, and experimental archaeology, providing a bridge between anthropology and evolutionary studies to neurosciences. Written by international experts in paleoanthropology and prehistoric archaeology, as well as neurobiology and psychology, the book explores how body perception and spatial capacity may have evolved to enhance a "prosthetic capacity" able to integrate the brain, body and technological discoveries into a single functional system. Chapters discuss the anatomy, function and evolution of the parietal cortex in human and non-human primates. In addition, the book covers the evolution of visuospatial cognition and how modern brain imaging can trace these changes back millions of years.

Human Reproductive and Prenatal Genetics, Second Edition provides application-driven coverage of key topics in human reproductive and prenatal genetics, including genetic control underlying the development of the reproductive tracts and gametogenesis, the genetics of fertilization and implantation, the genetic basis of female and male infertility, as well as genetic and epigenetic aspects of assisted reproduction. Also examined are the genetics and epigenetics of the placenta in normal and abnormal pregnancy, preimplantation genetic diagnosis and screening, and cutting-edge advances in noninvasive prenatal screening, prenatal genetic counseling, and bioethical and medicolegal aspects of relevance in the lab and clinic. This new edition has been fully revised to address new and evolving technologies in human reproductive genetics, with new chapters added on chromatin landscapes and sex determination, genetic alterations of placental development and preeclampsia, metabolism and inflammation in PCOS, pre-implantational genetic testing, maternal genetic disorders, bioethics, and future applications.

Insect Molecular Genetics: An Introduction to Principles and Applications, Fourth Edition provides the most recent advances and research in entomology and molecular genetics. It demonstrates the role molecular genetics plays in pest management and basic insect biology research, assuming readers have little to no prior knowledge on the subject. This newest edition features updates on the latest trends and discoveries, such as CRISPR-Cas genome editing methods, epigenetic inheritance, DNA amplification techniques, and molecular phylogenies. Certain chapter topics, including P-element mediated transformation and insect population molecular techniques, are condensed and updated to create a more comprehensive and concise read. This foundational text is a valuable resource for entomologists with limited training in molecular genetics, and will be an ideal source for pest control advisors who need to understand the vocabulary and methods that are used to solve entomological issues. Contains a new chapter on CRISPR-CAS and the basic biology of these systems related to arthropods Includes new and updated methods and examples of insect gene modification, along with discussions of regulatory and ethical issues Offers compiled and comprehensive terminology at the introductory level Illustrated with diagrams and tables to further explain key topics and concepts

It is difficult to forecast the There are 25 s contributed by distinguished contributors who have made valuable contributions to the field of conservation of animal biodiversity and improvement of livestock. The topics covered are ranging from cattle genetic resources, strategic action plan for sustainable management, conservation and genetics improvement, breeding strategies to improve milk productivity, production systems and breeding policies for genetic improvement, application of biotechnological tools for conservation and improving of animal genetic resources, bioinformatics and genome analysis in conservation, heat stress management etc.

Omics Technologies and Bio-Engineering: Towards Improving Quality of Life, Volume 2 is a unique reference that brings together multiple perspectives on omics research, providing in-depth analysis and insights from an international team of authors. The book delivers pivotal information that will inform and improve medical and biological research by helping readers gain more direct access to analytic data, an increased understanding on data evaluation, and a comprehensive picture on how to use omics data in molecular biology, biotechnology and human health care.

Mechanisms of DNA Recombination and Genome Rearrangements: Intersection between Homologous Recombination, DNA Replication and DNA Repair, Volume 601, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Homologous genetic recombination remains the most enigmatic process in DNA metabolism. The molecular machines of recombination preserve the integrity of the genetic material in all organisms and generate genetic diversity in evolution. The same molecular machines that support genetic integrity by orchestrating accurate repair of the most deleterious DNA lesions, however, also promote survival of cancerous cells and emergence of radiation and chemotherapy resistance. This two-volume set offers a comprehensive set of cutting edge methods to study various aspects of homologous recombination and cellular processes that utilize the enzymatic machinery of recombination. The chapters are written by the leading researches and cover a broad range of topics from the basic molecular mechanisms of recombinational proteins and enzymes to emerging cellular techniques and drug discovery efforts.

The Chemical Dialogue Between Plants and Beneficial Microorganisms provides foundational insights on plant beneficial microorganisms and their impact on the health and productivity of plants. Providing in-depth and recent updates about unexplored aspects of plant microbes interactions, the book includes the biological repertoire of arbuscular mycorrhizal association, molecular architecture of Rhizobium-plant symbiosis, and endophytes in transcriptional plasticity during host colonization by endophytes. The book also includes details about the mechanism of different plant beneficial microorganisms, how these differ, and their cross signaling. This book will be an important reference for researchers working on different plant beneficial microorganisms and their molecular arsenal.

The book presents conventional and modern breeding technologies in the vital areas of animal breeding, to stimulate more research, and to rapidly pass such modern techniques to scientific community. Various conventional breeding technologies used for selection and faster multiplication of superior cattle and buffalo germplasm have contributed significantly to increase in milk production, which were mainly due to the technologies developed in the areas of quantitative genetics and reproductive biology. These included methodologies for selection of females based upon their expected producing ability and young males based on the performance of progeny. Emerging developments in the areas of molecular marker systems in animals, genome maps, methods of detecting Quantitative Trait Loci (QTL) linkages, Marker Assisted Selection (MAS) etc., are latest tools to be used in breeding programmes for enhancing the rate of genetic progress. These modern techniques could be of great help for those traits, for which the conventional technologies have limitations in their use. Therefore, integration of molecular markers with conventional breeding technologies involving pedigree and phenotypic information are probable future breeding tools for genetic improvement of livestock and poultry.

Concepts and techniques in genomics and proteomics covers the important concepts of high-throughput modern techniques used in the genomics and proteomics field. Each technique is explained with its underlying concepts, and simple line diagrams and flow charts are included to aid understanding and memory. A summary of key points precedes each chapter within the book, followed by detailed description in the subsections. Each subsection concludes with suggested relevant original references.

Translating microRNA to the Clinic reviews the possibilities of current methodological tools and experimental approaches used by leading translational researchers. The book features the uses of micro ribonucleic acid as deployed in cancer targeting in biomarkers, diabetes, cardiovascular disease, and neurodegeneration, among many others. Pedagogically, the work concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field, promoting a cross-disciplinary communication between the sub-specialities of medicine, but in common with other books on the topic. In addition, the book emphasizes recent innovations, critical barriers to progress, the new tools that are being used to overcome them, and specific areas of research that require additional study to advance the field as a whole.

Chromatin Signaling and Diseases covers the molecular mechanisms that regulate gene expression, which govern everything from embryonic development, growth, and human pathologies associated with aging, such as cancer. This book helps researchers learn about or keep up with the quickly expanding field of chromatin signaling. After reading this book, clinicians will be more capable of explaining the mechanisms of gene expression regulation to their patients to reassure them about new drug developments that target chromatin signaling mechanisms. For example, several epigenetic drugs that act on chromatin signaling factors are in clinical trials or even approved for usage in cancer treatments, Alzheimer's, and Huntington's diseases. Other epigenetic drugs are in development to regulate various class of chromatin signaling factors. To keep up with this changing landscape, clinicians and doctors will need to stay familiar with genetic advances that translate to clinical practice, such as chromatin signaling. Although sequencing of the human genome was completed over a decade ago and its structure investigated for nearly half a century, molecular mechanisms that regulate gene expression remain largely misunderstood. An emerging concept called chromatin signaling proposes that small protein domains recognize chemical modifications on the genome scaffolding histone proteins, facilitating the nucleation of enzymatic complexes at specific loci that then open up or shut down the access to genetic information, thereby regulating gene expression. The addition and removal of chemical modifications on histones, as well as the proteins that specifically recognize these, is reviewed in Chromatin Signaling and Diseases. Finally, the impact of gene expression defects associated with malfunctioning chromatin signaling is also explored.

On Human Nature: Biology, Psychology, Ethics, Politics, and Religion covers the present state of knowledge on human diversity and its adaptative significance through a broad and eclectic selection of representative chapters. This transdisciplinary work brings together specialists from various fields who rarely interact, including geneticists, evolutionists, physicians, ethologists, psychoanalysts, anthropologists, sociologists, theologians, historians, linguists, and philosophers. Genomic diversity is covered in several chapters dealing with biology, including the differences in men and apes and the genetic diversity of mankind. Top specialists, known for their open mind and broad knowledge have been carefully selected to cover each topic. The book is therefore at the crossroads between biology and human sciences, going beyond classical science in the Popperian sense. The book is accessible not only to specialists, but also to students, professors, and the educated public. Glossaries of specialized terms and general public references help nonspecialists understand complex notions, with contributions avoiding technical jargon.

Advances in Agronomy continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied, and exemplary of the abundant subject matter addressed by this long-running serial.

DNA Replication Across Taxa, the latest volume in The Enzymes series summarizes the most important discoveries associated with DNA replication.

Methods in Enzymology: Visualizing RNA Dynamics in the Cell continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods visualizing RNA dynamics in the cell, and includes sections on such topics as identification of RNA cis-regulatory sequences, IRAS, IMAGEtags, MERFISH, plant RNA labeling using MS2, and visualization of 5S dynamics in live cells using photostable corn probe.

Advances in Genetics provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing future directions, This thematic volume focuses on the advances and the future potential of the rapidly growing field of entomopathogenic fungi. With a focus on the genetics and molecular biology behind the progress, techniques developed to study all aspects of these fungi will be highlighted, and topics will span from systematics of fungi to how a fungus infects an insect and how that insect responds.

Advances in Agronomy continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied, and exemplary of the abundant subject matter addressed by this long-running serial.