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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Genetics (non-medical)
Adenoviral Vectors for Gene Therapy, Second Edition provides
detailed, comprehensive coverage of the gene delivery vehicles that
are based on the adenovirus that is emerging as an important tool
in gene therapy. These exciting new therapeutic agents have great
potential for the treatment of disease, making gene therapy a
fast-growing field for research. This book presents topics ranging
from the basic biology of adenoviruses, through the construction
and purification of adenoviral vectors, cutting-edge vectorology,
and the use of adenoviral vectors in preclinical animal models,
with final consideration of the regulatory issues surrounding human
clinical gene therapy trials. This broad scope of information
provides a solid overview of the field, allowing the reader to gain
a complete understanding of the development and use of adenoviral
vectors.
This volume of Progress in Molecular Biology and Translational
Science introduces emerging strategies of studying RNA structure
and function using nanotechnological tools. The volume aims to
provide the readers with a novel view and give them opportunities
to think about how to incorporate the new technologies into their
own research.
Advances in Genetics provides the latest information on the rapidly
evolving field of genetics, presenting new medical breakthroughs
that are occurring as a result of advances in our knowledge of the
topic. The book continually publishes important reviews of the
broadest interest to geneticists and their colleagues in affiliated
disciplines, critically analyzing future directions.
Advances in Genetics provides the latest information on the rapidly
evolving field of genetics, presenting new medical breakthroughs
that are occurring as a result of advances in our knowledge of
genetics. The book continually publishes important reviews of the
broadest interest to geneticists and their colleagues in affiliated
disciplines, critically analyzing future directions.
Analytical Ultracentrifugation, the latest volume in Methods in
Enzymology, focuses on analytical ultracentrifugation. The scope of
this technique has greatly expanded in recent years due to advances
in instrumentation, algorithms and software. This volume describes
the latest innovations in the field and in the applications of
analytical ultracentrifugation in the analysis of macromolecules,
macromolecular assemblies, and biopharmaceuticals.
Advances in Genetics provides the latest information on the rapidly
evolving field of genetics, presenting new medical breakthroughs
that are occurring as a result of advances in our knowledge of
genetics. The book continually publishes important reviews of the
broadest interest to geneticists and their colleagues in affiliated
disciplines, critically analyzing furture directions.
Advances in Agronomy continues to be recognized as a leading
reference and a first-rate source for the latest research in
agronomy. Each volume contains an eclectic group of reviews by
leading scientists throughout the world. As always, the subjects
covered are rich and varied and exemplary of the abundant subject
matter addressed by this long-running serial.
Omic Studies of Neurodegenerative Disease: Part A is part of a
well-established international series on neuroscience that examines
major areas of basic and clinical research, along with emerging and
promising subfields. The book informs the reader on the current
state of the studies used to evaluate the mechanisms, causes, and
treatment of neurodegeneration through a combination of literature
reviews and examples of current research.
The field of genetics is rapidly evolving, and new medical
breakthroughs are occurring as a result of advances in our
knowledge of genetics. Advances in Genetics continually publishes
important reviews of the broadest interest to geneticists and their
colleagues in affiliated disciplines.
Advances in Agronomy continues to be recognized as a leading
reference and a first-rate source for the latest research in
agronomy. Each volume contains an eclectic group of reviews by
leading scientists throughout the world. As always, the subjects
covered are varied and exemplary of the myriad of subject matter
dealt with by this long-running serial.
This new volume of Methods in Enzymology continues the legacy of
this premier serial with quality chapters authored by leaders in
the field. This volume covers research methods in RNA folding and
dynamics, RNA-protein interactions and large RNPs.
Advances in Agronomy continues to be recognized as a leading
reference and a first-rate source for the latest research in
agronomy. Each volume contains an eclectic group of reviews by
leading scientists throughout the world. As always, the subjects
covered are varied and exemplary of the myriad of subject matter
dealt with by this long-running serial.
Epigenetics of Stress and Stress Disorders, a new volume in the
Translational Epigenetics series, examines the epigenetic
mechanisms involved in modifying DNA following prolonged stress or
trauma. This is accomplished through the evaluation of both the
physiological and molecular effects of stress on the body that can
eventually lead to stress disorders. The book begins by providing a
psychiatric, biological, and phenomenological foundation for
understanding stress disorders, before delving into the genomics of
stress disorders. From here, chapter authors discuss a range of
recent epigenetic research in the area, highlighting epigenome-wide
association studies (EWAS), exciting developments in noncoding RNA
studies, possible effects of prolonged stress on telomere
shortening, and the long-term physical effects of PTSD on the
health of patients. The book also examines the effect of adversity
during sensitive periods or development and across the life span.
The book concludes by looking at possible transgenerational
stress-induced epigenetic alterations on future offspring and
important areas of research for public health, along with the
potential for epigenetic therapeutics or "epidrugs."
The protein molecule is the basic building block of every living
entity. Its deficiency leads to restricted growth and development
of individuals. Globally, such malnutrition is on the rise due to
various reasons such as rapid population growth, stagnation of
productivity, and ever-rising costs. Millions of people, especially
in developing and under-developed countries, suffer from protein
malnutrition and the only possible solution is to encourage farmers
to grow high-protein food legume crops in their fields for domestic
consumption. This, however, could be possible if farmers are
provided with new cultivars with high yield, and resistance to
major insects, diseases, and key abiotic stresses. The major food
legume crops are chickpea, cowpea, common bean, groundnut, lentil,
pigeonpea, and soybean. Predominantly, the legume crops are grown
under a subsistence level and, therefore, in comparison to cereals
and horticultural crops their productivity is low and highly
variable. The crop breeders around the globe are engaged in
breeding suitable cultivars for harsh and changing environments but
success has been limited and not up to needs. With the recent
development of new technologies in plant sciences, efforts are
being made to help under-privileged farmers through breeding new
cultivars which will produce more protein per unit of land area. In
this book, the contributors analyze the constraints, review new
technologies, and propose a future course of crop breeding programs
in seven cold and warm season legume crops.
The series Advances in Stem Cell Biology is a timely and expansive
collection of comprehensive information and new discoveries in the
field of stem cell biology. iPSCs - Novel Concepts, Volume 15
addresses how important induced pluripotent stems cells are and how
can they can help treat certain diseases. Somatic cells can be
reprogrammed into induced pluripotent stem cells by the expression
of specific transcription factors. These cells have been
transforming biomedical research over the last 15 years. This
volume will address the advances in research of how induced
pluripotent stem cells are being used for treatment of different
disorders, such as liver disease, type-1 diabetes, Parkinson's
disease, macular degeneration of the retina and much more. The
volume is written for researchers and scientists in stem cell
therapy, cell biology, regenerative medicine and organ
transplantation; and is contributed by world-renowned authors in
the field.
The Pacific Symposium on Biocomputing (PSB) 2017 is an
international, multidisciplinary conference for the presentation
and discussion of current research in the theory and application of
computational methods in problems of biological significance.
Presentations are rigorously peer reviewed and are published in an
archival proceedings volume. PSB 2017 will be held on January 4 -
8, 2017 in Kohala Coast, Hawaii. Tutorials and workshops will be
offered prior to the start of the conference.PSB 2017 will bring
together top researchers from the US, the Asian Pacific nations,
and around the world to exchange research results and address open
issues in all aspects of computational biology. It is a forum for
the presentation of work in databases, algorithms, interfaces,
visualization, modeling, and other computational methods, as
applied to biological problems, with emphasis on applications in
data-rich areas of molecular biology.The PSB has been designed to
be responsive to the need for critical mass in sub-disciplines
within biocomputing. For that reason, it is the only meeting whose
sessions are defined dynamically each year in response to specific
proposals. PSB sessions are organized by leaders of research in
biocomputing's 'hot topics.' In this way, the meeting provides an
early forum for serious examination of emerging methods and
approaches in this rapidly changing field.
This document is exclusively dedicated to DNA. It explains the
secrets of DNA from all corners. Presented in a simple, lucid
manner; it will useful to all involved in bioscience. In all it
consists 12 chapters, figures, photos and a wholesome glossary of
the terms related to DNA.
"Conceptual Breakthroughs in Evolutionary Genetics" is a pithy,
lively book occupying a special niche-the conceptual history of
evolutionary genetics- not inhabited by any other available
treatment. Written by a world-leading authority in evolutionary
genetics, this work encapsulates and ranks 70 of the most
significant paradigm shifts in evolutionary biology and genetics
during the century-and-a-half since Darwin and Mendel. The science
of evolutionary genetics is central to all of biology, but many
students and other practitioners have little knowledge of its
historical roots and conceptual developments. This book fills that
knowledge gap in a thought-provoking and readable format.
This fascinating chronological journey along the many conceptual
pathways to our modern understanding of evolutionary and genetic
principles is a wonderful springboard for discussions in
undergraduate or graduate seminars in evolutionary biology and
genetics. But more than that, anyone interested in the history and
philosophy of science will find much of value between its
covers.
Provides a relative ranking of 70 seminal breakthroughs and
paradigm shifts in the field of evolutionary biology and
geneticsModular format permits ready access to each described
subjectHistorical overview of a field whose concepts are central to
all of biology and relevant to a broad audience of biologists,
science historians, and philosophers of scienceExtensively
cross-referenced with a guide to landmark papers and books for each
topic
Lecture provides an overview of the progress made in molecular
medicine applying genetics and genomics to the understanding,
diagnosis, and treatment of human diseases. Specifically, the
methods for identifying genes involved in human diseases are
described. Examples from 10 genes and diseases will be provided,
drawing on the author's research. Topics include examples from
simple Mendelian diseases, such as cystic fibrosis, inherited
cancers, oncogenes activated by chromosomal translocations, host
genes involved in infectious disease, genes identified via
genomewide association studies, pathogens causing cancer, and gene
families contributing to multiple diseases. For each example,
historical details will be provided as background for readers to
understand the context and process of the discoveries, technologies
explained, and current understanding and treatment implications
detailed.
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