In this "enlightening" (Jane Brody, New York Times) book, Harvard Medical School physician Angelo E. Volandes offers a solution to traumatic end-of-life care: talking, medicine's oldest tool. There is an unspoken dark side of American medicine--keeping patients alive at any price. Two thirds of Americans die in healthcare institutions, tethered to machines and tubes at bankrupting costs, even though research shows that most prefer to die at home in comfort, surrounded by loved ones. Dr. Angelo E. Volandes believes that a life well lived deserves a good ending. Through the stories of seven patients and seven very different end-of-life experiences, he demonstrates that what people with a serious illness, who are approaching the end of their lives, need most is not new technologies but one simple thing: The Conversation. He argues for a radical re-envisioning of the patient-doctor relationship and offers ways for patients and their families to talk about this difficult issue to ensure that patients will be at the center and in charge of their medical care. It might be the most important conversation you ever have.

Africa is known both for having a primarily youthful population and for its elders being held in high esteem. However, this situation is changing: people in Africa are living longer, some for many years with chronic, disabling illnesses. In Ghana, many older people, rather than experiencing a sense of security that they will be respected and cared for by the younger generations, feel anxious that they will be abandoned and neglected by their kin. In response to their concerns about care, they and their kin are exploring new kinds of support for aging adults, from paid caregivers to social groups and senior day centers. These innovations in care are happening in fits and starts, in episodic and scattered ways, visible in certain circles more than others. By examining emergent discourses and practices of aging in Ghana, Changes in Care makes an innovative argument about the uneven and fragile processes by which some social change occurs. There is a short film that accompanies the book, “Making Happiness: Older People Organize Themselves� (2020), an 11-minute film by Cati Coe. Available at: https://doi.org/doi:10.7282/t3-thke-hp15

How do digital technologies shape both how people care for each other and, through that, who they are? With technological innovation is on the rise and increasing migration introducing vast distances between family members--a situation additionally complicated by the COVID-19 pandemic and the requirements of physical distancing, especially for the most vulnerable – older adults--this is a pertinent question. Through ethnographic fieldwork among families of migrating nurses from Kerala, India, Tanja Ahlin explores how digital technologies shape elder care when adult children and their aging parents live far apart. Coming from a country in which appropriate elder care is closely associated with co-residence, these families tinker with smartphones and social media to establish how care at a distance can and should be done to be considered good. Through the notion of transnational care collectives, Calling Family uncovers the subtle workings of digital technologies on care across countries and continents when being physically together is not feasible. Calling Family provides a better understanding of technological relationality that can only be expected to further intensify in the future.

Knapp und praxisorientiert beschreibt das Handbuch die wichtigsten Erkrankungen im Alter.
o Morphologische und pathophysiologische Grundlagen der Erkrankungen, Symptome und adaquate Theorien
o Besonders ausfuhrlich: Herz-Kreislauf-Erkrankungen, die Hypertonie mit ihren kardialen, renalen und zerebralen Komplikationen, Nierenerkrankungen, Diabetes mellitus, Sturze im Alter
o Zusatzliche Schwerpunkte die haufigsten Karzinome und deren Behandlung, Pharmakokinetik, Pharmakodynamik.
Ein Standardwerk zum raschen Nachschlagen, das Sie mit aktuelle Praxis-Informationen und neuesten Literaturhinweisen zuverlassig bei Ihrer Diagnostik und Therapie unterstutzt."

Dieses Open-Access-Buch befasst sich kritisch mit der Anwendung freiheitseinschrankender Massnahmen (FeM) bei Menschen mit Demenz in professionellen Sorgebeziehungen, die sowohl im Hinblick auf ihren vermeintlichen Nutzen als auch auf ihre ethische Tragweite zu hinterfragen sind. In einer disziplinubergreifenden Analyse des Phanomens von FeM bei Menschen mit Demenz werden Diskurse und Erkenntnisse aus Pflegewissenschaft, Gerontologie, Rechtswissenschaft und Ethik gebundelt, zueinander in Beziehung gesetzt und erweitert. Die empirisch informierte Gesamtdarstellung wird dabei erganzt durch eine tiefgreifende Reflexion der Personalitat, Vulnerabilitat und Leiblichkeit von Menschen mit Demenz. Davon ausgehend werden konkrete Kategorien und konzeptionelle Zugange zur Bewertung und Einzelfallprufung von FeM in professionellen Sorgebeziehungen entwickelt.

In our highly interconnected and globalized world, people often pursue their aspirations in multiple places. Yet in public and scholarly debates, aspirations are often seen as the realm of younger, mobile generations, since they are assumed to hold the greatest potential for shaping the future. This volume flips this perspective on its head by exploring how aspirations are constructed from the vantage point of later life, and shows how they are pursued across time, space, and generations. The aspirations of older people are diverse, and relate not only to aging itself but also to planning the next generation’s future, preparing an "ideal" retirement, searching for intimacy and self-realization, and confronting death and afterlives. Aspiring in Later Life brings together rich ethnographic cases from different regions of the world, offering original insights into how aspirations shift over the course of life and how they are pursued in contexts of translocal mobility. This book is also freely available online as an open-access digital edition.​

BACE inhibitors and their use in the treatment of Alzheimer's Disease

BACE (β-site of APP cleaving enzyme) is a critical component in Alzheimer's Disease (AD), and the development of BACE inhibitors shows great potential as a therapy for the disease. "BACE: Lead Target for Orchestrated Therapy of Alzheimer's Disease" covers virtually all aspects of BACE from initial identification, discovery of inhibitors, and challenges in clinical development, while providing a global understanding essential for productive and successful drug discovery.

This book details the story of the discovery of BACE and its role in AD and comprehensively discusses:

The development of BACE inhibitors as therapeutics for Alzheimer's disease

The research that led to the identification of BACE

New BACE inhibitors currently being clinically tested

ADME (absorption, distribution, metabolism, excretion) and clinical trial design--topics not addressed in current field literature

Cutting-edge technology such as high-throughput screening, structure-based drug design, and QSAR in context of BACE inhibitors and Alzheimer's drug discovery

Other approaches to BACE inhibition based on interaction with the precursor protein APP

By enhancing the reader's understanding of the various aspects of the BACE drug-discovery process, this much-needed reference will serve as a key resource for all scientists involved in Alzheimer's research--and inspire new approaches to treatment of AD.

As the Baby Boom generation ages, an increased need for geriatric specialty care becomes particularly important. This shift will especially affect ophthalmology, as the occurrence of common visual disorders such as cataracts, macular degeneration, glaucoma and diabetic retinopathy increases with age. This book anticipates this pending and inevitable demographic shift and fulfills the need for a practical, "bread-and-butter" approach to Geriatric Ophthalmology.

This unique book reviews the information available in the literature regarding the new syndrome, frailty, in patients with various renal conditions, such as acute kidney injury, chronic kidney disease, as well as dialysis and transplant patients. The topic is of importance in nephrology, specifically nephrogeriatrics, since frailty is a condition affecting many elderly patients and which is becoming increasingly common in medical practice. As such, there is a considerable need for information to assist professionals treating these patients. The book includes chapters on the frailty syndrome (definition, evaluation and treatment), the main geriatric syndromes (gait disorder, falls, incontinence, and delirium), the main renal syndromes (acute renal injury, chronic kidney disease) as well as dialysis and kidney transplant, and the relationship between geriatrics and renal syndromes. Frailty and Kidney Disease: A Practical Guide to Clinical Management is an essential resource for general practitioners, researchers, internal medicine physicians, geriatricians, and nephrologists.

The growing number of older adults in the United States poses a significant challenge to families, healthcare systems, mental health services, and many other caregiving groups. Using the Grand Challenges for Social Work initiative as a framework, this text evaluates critical policies and issues pertaining to older adults, identifying both the overall systemic inequalities currently working against older adults as well as specific areas that require updated policies and interventions. It calls for active attention to the implementation of science-based research, policy, and practices to promote health and well-being. Among the topics addressed: Family violence against older adults Disaster planning and preparedness Building financial capability for aging families Health needs of incarcerated older adults Closing the gap in healthcare services for older adults Social isolation and its effects on mental health and well-being A useful gerontology resource for students, social work scholars, and practitioners, Gerontological Social Work and the Grand Challenges advocates for justice and equal opportunity for older adults, and highlights important social issues that must be urgently addressed in the near future.

Die Altenbetreuung wird in diesem Handbuch aus der Sicht von unterschiedlichen Fachdisziplinen umfassend vorgestellt. Namhafte Fachleute aus den Bereichen der Altenpflege, Medizin, Psychologie und Therapie sowie Angehoerige bzw. Selbsthilfegruppen berichten uber praxisbezogene Massnahmen zur Loesung von leichteren bis schwerwiegenden Problemen, die mit dem AElterwerden verbunden sind. Die Themenkreise spannen sich von stationaren und ambulanten Versorgungsstrukturen, Diagnostik und Therapie psychischer Erkrankungen im Alter, bis hin zu Rehabilitation, Kommunikation, Psychotherapie, Palliativmedizin und alternativen Betreuungsformen. Die zweite Auflage wurde durch ein Kapitel zu den Organisationsstrukturen der Altenbetreuung in Deutschland, OEsterreich und der Schweiz erganzt. Alle Kapitel wurden neu strukturiert und uberarbeitet. Dieses Buch gibt allen professionellen Helfern der Altenpflege sowie Angehoerigen einen praxisrelevanten UEberblick zur Betreuung und Versorgung von alteren Menschen.

In two volumes, the APA Handbook of Clinical Geropsychology offers a well-balanced scientist-practitioner approach, with chapters that succinctly review empirical research across a broad range of areas and offer practical approaches for the application of theory to everyday practice with the aging population. The handbook reviews the history of clinical geropsychology and geropsychology practice, to help the reader better understand how the field has grown over the past 30 plus years and to assess the several directions in which it is headed. Chapter authors highlight strength-based approaches to human development and aging, review the status of evidence-based treatment, explore the interface of geriatric medicine and clinical psychotherapy, review several ""normal aging"" areas of research, and discuss such common psychological, neurological, and other medical issues common in aging as depression, late-life anxiety disorders, schizophrenia, alcohol abuse and substance misuse, suicidal behaviour, mild cognitive impairment, Alzheimer's, and many more. The reader will not only gain knowledge about foundational competencies in the field of clinical geropsychology, but will also find a treasure of information related to assessment, intervention, and consultation in this continually evolving field.

Supported by the latest scientific data, this book serves as a guide to the clinical assessment of women's health during the second half of life (post-reproductive years), including approaches to the management of the most frequent age-related diseases and disorders and the most recent advances in treatment. In addition, it discusses preventive aspects of healthcare in post-reproductive women, identifying lifestyle measures to enhance healthy aging. By highlighting research gaps, it promotes the development of quick and easy-to-use assessment tools and predictive markers of age-related co-morbidities. As such, the book is a valuable resource for researchers and clinicians alike.

Der etwas andere Ratgeber zur Vorbeugung von Demenzerkrankungen packt uns bei unseren Schwachen und provoziert: Wir erfahren, was wir tun koennen, um unseren Weg zu einer Demenz zu beschleunigen. Wir koennen sogar wahlen, ob wir den neurodegenerativen oder den vaskularen Weg bevorzugen. Fur alle, die es satt haben, auf ihren kognitiven Verfall im Alter nur passiv zu warten: Wie wir mit Eigeninitiative und Selbststandigkeit den zugigen Abbau unseres Gedachtnisses foerdern. Die Autoren geben Tipps und Anregungen aus den Bereichen Altern, Ernahrung, Bewegung, Bildung, Sozialkontakte, Sinnesorgane, Alkohol, Drogen und Lifestyle.

Tipps fur eine abgestimmte Behandlung von geriatrisch urologischen Patienten Das Praxisbuch zur Urogeriatrie. Als erster Professor fur Urogeriatrie Deutschlands schafft der Autor den Transfer von hilfreichen Erkenntnissen aus der Geriatrie in die Urologie und umgekehrt. Die Zunahme alterer, multimorbider Patienten ist in der Urologie besonders stark. Inkontinenz ist eines der fuhrenden Leiden im hoeheren Lebensalter. Fachubergreifend, auf der Basis der aktuellen Wissenschaft und einer jahrelangen Erfahrung aus Klinikpraxis und Forschung, werden relevante Aspekte der Geriatrie, die bei der Behandlung multimorbider, urologischer Patienten berucksichtigt werden sollten, ubersichtlich und praxisnah erlautert. Dazu zahlen Themen wie: Einbinden geriatrischer Assessments in die urologische Diagnostik Einbeziehung der geistigen und koerperlichen Ressourcen in die Therapieentscheidung Nebenwirkungen und Wechselwirkungen urologischer Praparate Polypharmazie Demenz und andere Komorbiditaten Kognitive Veranderungen nach einer urologischen Operation Jedes Kapitel enthalt Tabellen und Entscheidungshilfen, die es dem Leser erlauben, schnell die wichtigsten Punkte fur den geriatrischen Patienten zu prufen. Fur alle Urologen, aber auch Allgemeinmediziner, Internisten, Geriater, die diese Patientengruppe, die eine ganzheitliche Behandlung verfolgen. Das Buch entstand in Zusammenarbeit mit dem Arbeitskreis Geriatrische Urologie. Es moechte durch den fachubergreifenden, interdisziplinaren Blick, ein UEberdenken standardisierter Therapien anregen.

This book explores medical nonadherence to treatment and management of psychiatric disorders across the lifespan. Leading experts in the field, specializing in a range of mental health problems describe the impact of nonadherence in the treatment of children, adolescents, transition age youths, adults, and older adults. The book eloquently articulates the key elements of effective physicians and offers clinical pearls on professionalism, empathy, and the doctor-patient relationship-a key component to solving treatment nonadherence. This volume focuses on solutions for improved clinical outcomes, including communication skills, empathy and building trust, motivational interviewing techniques and the use of technology. Psychiatric Nonadherence is an excellent resource for all clinicians who care for individuals with psychiatric illness. This timely reference will provide guidance to enhance effective treatment adherence for a wide array of medical practitioners, including child and adolescent, adult forensic, and geriatric psychiatrists, addiction medicine specialists, primary care physicians, psychologists and nurses.

Although very little can be done to alter the course of dementia, much can be done to maximize the quality of life of people with the condition. Research as well as practical experience suggest that behavior management, especially through programs that provide meaningful and constructive activity, is currently the most effective treatment.

In "Keeping Busy," James Dowling describes a variety of activities designed to bring meaning and enjoyment to the lives of persons with dementia. The activities are organized by general categories such as music, exercise, horticulture, pets, humor, and social events. The largest section deals with communication and includes word games that help people strengthen their remaining verbal skills. The description of each activity includes step-by-step instructions, as well as tips on how to adapt it for small or large groups, for individuals at home or in an organization, or people who are bedridden.

This timely and critical book takes on a new phenomenon facing the United States and poses the stark question: Will the United States be prepared by 2050, when its older population doubles and we become a majority-minority society? In the authors' response, scholars, policy leaders and the public are provided with the background and information that connects these two trends to contemporary public policy debates. Written with clarity and expertise, this book illuminates the changes and challenges that face the nation by concisely addressing a wide range of topics, including immigration reform, the politics of aging, and health and retirement security, and provides a glimpse of how the "next America" might look. The authors draw on current data about longevity, diversity and the growing Hispanic population in particular, to unfold the social, cultural, policy and political implications for an aging and diversifying population. With case studies and real-world examples, the book outlines and analyzes the possible impact of this phenomenon on issues like governance, public benefits, the long term care work force and national security, and builds a broader framework with which to understand them. With combined experience in academia, government and policy advocacy, the authors tackle the dramatic changes occurring across the United States and offer a road map to not only understanding but addressing these challenges and opportunities with reason and responsibility. Key Features: Presents the most current statistics and data on demographics Written by an interdisciplinary team with combined experience in academia, government and policy advocacy Includes case studies and real-world examples to build a broader framework of understanding Addresses social, policy, cultural and political challenges facing a rapidly changing population and offers rational and respectful responses

Geriatric Notes is an essential quick reference for the advanced practice provider (APP) who provides care to elders in the outpatient setting, such as nursing homes, family practice, or home health. With a practical, accessible, and concise approach, it offers an easy to understand overview of the most common diagnoses, topics, and symptoms encountered in the aging population. Designed to offer access to the basics, this guide provides tables and bullet points for easy reference. Sections include health promotion, neurology and psychiatry, cardiovascular, pulmonary, gastroenterology, genitourinary, rheumatology, dermatology, endocrinology, labs, Beers list, and common presentations.

This book examines the critical issues in understanding and treating depression and suicidal behavior in late life. Chapters cover the biology, psychology, epidemiology, and sociology of depression and suicidal behavior in late life.

Written by leading scholars, this esteemed text on global aging is distinguished by its unique perspective on universal similarities and sociocultural differences across nations. Fully revised, updated, and reorganized, the second edition presents-comprehensive coverage of major topics in social gerontology, expands its treatment of health behavior, health care, families, caregiving, older workers, and retirement. It delivers new information on living environments, religious beliefs and practices; environmental threats; cross-cultural views of dementia; ageism in advertising; age-friendly communities; global immigration and cultural assimilation, and end-of-life caregiving, to name a few.The second edition also offers additional case studies, first-person narratives and focused essays to enhance core material and a greater number of non-Western contributors. The topical essays reflect changing mores and current issues affecting societies and the aging experience. Discussion questions conclude each chapter, and an Instructor's Manual and Power Point slides are available to instructors. Print version of the book includes free, searchable, digital access to entire contents! New to the Second Edition: Expanded content on health beliefs and health behavior, religious belief and practice, environmental threats, housing and living environments, physical security, consumer control of health care, family life, and more Additional topics on global immigration and cultural assimilation, age portrayals in advertising, voluntarism, and the use of social media in caregiving. Abundant new and expanded essays New case studies and first-person narratives Many more non-western contributors Key Features: Delivers comprehensive coverage of major topics in gerontology Uses a unique comparative, cross-national perspective Authored by world-renowned aging scholars Includes case studies/essays/personal narratives to enliven core information Provides the most comprehensive demographic data on aging around the world

This text focuses on the under-recognized and undertreated problem of addiction in later life. The widespread lack of clinical knowledge about this patient population can be traced to several sources: the systematic exclusion of older individuals from clinical trials; their reluctance to seek medical help owing to stigma and shame; the fact that additive disorders may be disguised by concurrent medical conditions; a lack of screening instruments tailored to an older population; and the low sensitivity of standard diagnostic criteria for detecting addiction in middle-aged and elderly adults who do not display the occupational and legal "red flags" seen in younger individuals. This volume provides the reader with a clear sense of the surprisingly high prevalence of alcohol and substance use disorders in older adults. For each of the major classes of addictive substances, both prescribed and illicit, this book highlights the key clinical issues that can complicate successful diagnosis. The authors describe strategies for initial engagement with the patient, including screening instruments, brief interventions which can be adapted to a primary care setting, emerging web-based and mobile technologies, and treatment strategies which are tailored to the age-appropriate needs of older adults, including older women - who have been found to be especially vulnerable to prescription drug misuse. With the aging of the baby boomers, a generation arriving in middle-age with greater exposure to alcohol and drugs than any previous cohort, the need for successful identification and effective treatment of alcohol and substance use disorders in later life has become a clinical imperative. Addiction in the Older Patient, whose editors bring more than 40 years of combined research and clinical experience in the field of addiction treatment, offers a comprehensive introduction to this underexplored and timely topic. This text synthesizes current clinical evidence to support the most effective strategies for discovering and treating addictive disorders in our older patients.