The decline of infections, starvation, warfare, heart attack and stroke has allowed people to reach extreme old age but ushered in disability, dementia and degenerative disease, with profound consequences for the self and society. Dr Guy Brown explores these vital issues at various levels, from the cell, to the whole body, to society.

The lives of urban Chinese daughters have changed. Education and employment have propelled them from dependency to self-sufficiency, resulting in new attitudes and lifestyles. However, traditional filial obligation has remained. This book asks why it continues and how it is currently discharged, focusing on the emotion work daughters do to sustain the parent relationship, deal with conflict and maintain their self-esteem. Based on interviews with women living in Hong Kong, Singapore and mainland China, the book further explores whether the structural or relational motivations underpinning support and care may be less important than the standards daughters impose on themselves; why care may be discontinued or not undertaken in the first place; why care provided to parents may be different from in-laws, and the importance of domestic helpers to the modern caregiving paradigm. To undertake this exploration, a typology of support and care was created, allowing for the first time to distinguish between what daughters do for healthy parents and in-laws versus parents who require temporary or full time care, specifically addressing how providing support and care affects the daughters' well-being.

Though mental health recommendations for the elderly is rapidly evolving, the few current textbooks on this subject are either too voluminous or complex for regular review by clinicians, and most do not contain the latest information available in the field. Written by experts in geriatric psychiatry, this book provides a comprehensive yet concise review of the subject.The text covers topics that include the social aspect of aging, treatment and diagnosis options unique to the elderly in need of psychiatric care, policy and ethics, and particular geriatric health concerns that may influence psychiatric considerations. Psychiatric Disorders Late in Life is the ultimate resource for practicing psychiatrists, physicians, geriatricians, and medical students concerned with the mental healthcare of the elderly.

Newly revised and updated, this book provides geriatricians and orthopedic surgeons with the most vital tools to treat elderly patients who sustain a variety of fractures. The text uniquely encompass the etiologies of fracture in the elderly, perioperative management, the surgical treatment of common fractures in the elderly, as well as rehabilitation and prevention in the older patient. It focuses on the most current data and opinions regarding assessment and management of geriatric conditions that predispose the elderly to fracture, perioperative complications and subsequent functional decline. Unlike any other text, experts in both orthopedics and geriatrics review the content of each chapter for readability and appeal to his/her respective discipline, making this the physician's ultimate guide to treating elderly patients with injuries. Fractures in the Elderly, Second Edition is a valuable resource for geriatricians, orthopedic surgeons, physiologists, and rehabilitation specialists.

This book provides an overview of recent advances in the study of aging and aging related diseases, discussing the topics at individual, organ, tissue, cell, and molecular levels. It also presents studies on the biomarkers of aging and anti-aging interventions. Aging has been becoming a global health problem. However it was not possible to determine aging as we usually diagnose a disease because there are few biomarkers for age estimation. Since ancient times, people have been seeking anti-aging substances and methods for achieving immortality, while the scientific study of aging has only existed for 100 years. This book appeals to researchers both in institutes and in pharmaceutical companies interested in further studies in this field.

This open access book provides a comprehensive perspective on the concept of ageism, its origins, the manifestation and consequences of ageism, as well as ways to respond to and research ageism. The book represents a collaborative effort of researchers from over 20 countries and a variety of disciplines, including, psychology, sociology, gerontology, geriatrics, pharmacology, law, geography, design, engineering, policy and media studies. The contributors have collaborated to produce a truly stimulating and educating book on ageism which brings a clear overview of the state of the art in the field. The book serves as a catalyst to generate research, policy and public interest in the field of ageism and to reconstruct the image of old age and will be of interest to researchers and students in gerontology and geriatrics.

This text provides a comprehensive, state of the art review of this field and will serve as a resource for urologists, colorectal surgeons, geriatricians, and gynecologists as well as researchers interested in neuromuscular phenomena in the pelvis. The book also reviews new data regarding risk factors for pelvic floor muscle dysfunction and profiles new minimally invasive surgical strategies for well known pelvic disease processes. Each chapter is chock full of data from landmark trials which have been published over the past few years and placed in context with respect to current management techniques for pelvic floor disorders. Written by experts in their field, Pelvic Floor Dysfunction and Pelvic Surgery in the Elderly: An Integrated Approach provides a concise yet comprehensive summary to help guide patient management.

This book presents a comprehensive and state-of the-art approach to vascular disease for the geriatric patient, focusing on vascular pathology and interventions but also on perioperative care, anesthetic care, functional outcomes and quality of life, as well as ethical considerations that impact decision making. The book addresses open and endovascular interventions in different vascular beds, as well as preoperative workup and optimization, anesthetic considerations, all aspects and expectations of the postoperative care and recovery and is the only book to include specialize in the intricacies of the care of the geriatric patients, the challenging recovery and neurocognitive changes, and ethical considerations for the end stage geriatric patient or in the setting of postoperative complications. Written by experts in the field, each section addresses patient selection, pre-operative considerations, technical conduct of the most common operations with open or endovascular options, and avoiding complications. A brief review of the existing literature addressing the particular topic follows in each section. With its concise yet comprehensive summary of the field, Vascular Disease in Older Adults is the ultimate resource for geriatricians, cardiologists, surgeons, anesthesiologists, and all physicians of who care for the aging patient with vascular disease.

This book provides a current perspective on alcohol and aging to better understand the trends, costs, benefits, and clinical and community evidenced-based strategies. This book embraces not only the physical, cognitive, psychological, and social health benefits of moderate drinking in the elderly, it also delves into the risks of excessive drinking, including physical and psychiatric morbidity, neurodegeneration, medication complications, and accidents and injuries, and loss of independence. Written by experts in the field, this book is the only current text that includes the most current scientific, research, empirical, and practice information alongside a comprehensive review of the status of the field that will help guide alcohol use management and stimulate future research. Alcohol and Aging is the ultimate resource for all researchers, educators, clinicians, and professionals working with older adults who drink.

Psychological, social, and spiritual care is as important as physical care at the end of life. Yet caregivers often feel ill-equipped to give that nonphysical care. This book shows how to do it. The book addresses all caregivers who attend dying patients: doctors, nurses, chaplains, clergy in the pastorate, social workers, clinical psychologists, family caregivers, and others. It covers such topics as the functional and emotional trajectories of dying; the varied approaches of patients and caregivers to end-of-life decisions; culturally based beliefs about dying; the differences between depression and grief; and people's views about the right time to die, the death experience itself, and the afterlife. For each topic the book introduces core concepts and summarizes recent research about them. The book presents much of its material in readable tables for easy reference; applies the material to real-life cases; lists the main "take home" points for each chapter; and gives references for additional reading. The book helps caregivers anticipate the reactions of patients and survivors to end-of-life traumas and suggests how caregivers can respond insightfully and compassionately. At the same time the book challenges caregivers to think through their own views about death and dying. This book, therefore, is a must-read for all caregivers professional and nonprofessional alike who strive to give their patients comprehensive, high-quality end-of-life care.

This book focuses on the circumstances that lead to the marked increased vulnerability of seniors and are most challenging to clinicians including the presence of multiple chronic medical conditions, variable losses of physiological function, and heterogeneity among individuals. Written by the experts who lead the initiative to deliver high quality surgical and medical care to the elderly, Geriatrics for Specialists is the first book of its kind to provide the comprehensive knowledge specialists and associated generalists need to deliver quality health care to seniors. With topics on important cross cutting issues like frailty, delirium and polypharmacy and specialty chapters on emergency medicine, anesthesia, many surgical and medical disciplines and rehabilitation, this book provides clinicians the knowledge and tools needed to evaluate, treat and manage the unique needs of seniors. Geriatrics for Specialists was created as a resource for specialist, generalists and allied health professionals and their students and trainees who care for elderly patients.

This volume provides insight into the pivotal roles of stem cells, exosomes and other microvesicles in biofunction and molecular mechanisms and their therapeutic potential in translational nanomedicine. It further highlights evidence from recent studies as to how stem cell derived exosomes and microRNAs may restore and maintain tissue homeostasis, enable cells to recover critical cellular functions and begin repair regeneration. These early studies in animal models of aging also show evidence of improved immune, cardiovascular and cognitive functions as well as improved health span and life span. The use of exosomes from body fluids to define specific biomarkers for various tumors may also clear the path to patient-targeted treatments by developing exosome-derived microRNA based cancer therapeutics. It is essential reading for graduate students, research fellow and biomedical researchers in academia or the pharmaceutical or biotech industries.

The present book intends to provide an update on immunosenescence and how deficiencies in the immune system contribute to a higher susceptibility to infections, decline in organ function, reduced vaccination responses, age-related disease and the ageing process itself, negatively affecting longevity. Our focus is on the main changes in immune system cells and their products occurring during the ageing process and the possible consequences for health and disease. This includes: discussion of the modulatory and/or suppressive mechanisms associated with the alterations in T regulatory cells, B regulatory cells and Myeloid Derived Suppressor cells; changes in the immune system observed in chronic neurodegenerative diseases, cancer, lung disease and frailty will also be discussed. Most importantly we provide recent literature information about possible interventions (focusing on physical activity) that could alleviate the negative effects of immunosenescence. The Ageing Immune System and Health is a comprehensive guide on the field intended to all physicians, researchers, professors and students interested on relationship between immune system, ageing and health.

This book discusses theoretical issues, standards, and professional considerations arising when legal and health practitioners undertake legal capacity assessments in the context of wills, enduring powers of attorney and advance health directives. The potential loss of cognition can erode autonomy as individuals lose the ability to make their own legally recognised decisions. This is an inescapable problem with significant legal, social, health and policy repercussions. This work synthesises and critically analyses the existing literature, including some of the best assessment models and guiding principles internationally, to generate a new methodology and understanding of what capacity assessment best practice means. This includes the impact of assessments on individual autonomy - the ideal method building upon respect for both autonomy as well as fundamental human rights. The triggers to assess capacity, who to involve in the assessment process, as well as how to conduct that assessment process are discussed. The crucial relationship between the legal and health professionals involved in assessments, including growing concerns around practitioner liability, is also explored. This analysis is undertaken through the innovative use of a therapeutic jurisprudence lens, the effect of which is to contribute new knowledge to this complex field.

This book documents the state of the art in the field of ambient assisted living (AAL), highlighting the impressive potential of novel methodologies and technologies to enhance well-being and promote active ageing. The coverage is wide ranging, with sections on assistive devices, elderly people monitoring, home rehabilitation, ICT solutions for AAL, living with chronic conditions, robotic assistance for the elderly, sensing technologies for AAL, and smart housing. The book comprises a selection of the best papers presented at the 7th Italian Forum on Ambient Assisted Living (ForitAAL 2016), which was held in Pisa, Italy, in June 2016 and brought together end users, technology teams, and policy makers to develop a consensus on how to improve provision for elderly and impaired people. Readers will find that the expert contributions offer clear insights into the ways in which the most recent exciti ng advances may be expected to assist in addressing the needs of the elderly and those with chronic conditions.

The fact that there are special problems in the care of the elderly in the community is ample justification for writing a separate volume on the subject. The knowledge that there are increasing numbers of older people in virtually every country in the world makes it all the more important that the family physician should have sympathy with and understanding of the problems of them, since they are lilcely to make up a significant part of his worlcload and, increasingly, will take up more of his time and energy. There is a progressive amount of disability with advancing years, and this is particularly true of those aged 75 years and over. Increasing age is associated with serious impairment of hearing and vision, senses which younger people take for granted. Old age sees the arrival of major diseases of middle age with much greater frequency, such as ischaemic heart and cerebrovascular disease, diabetes mellitus and osteoarthritis. There are other disorders that are virtually confined to the elderly, such as fractures of the femoral neck, Paget's disease and myeloma. We now know that the disintegration of the con ducting tissue of the heart is largely an age-related phenomenon. Ageing processes affect every major organ system in the body and the impairment of physiological perfor mance resulting from these affects the elderly individual's response to infections, disease and environmental changes in complex ways that are not seen in younger people."

The book describes the major degenerative processes and pathologies exacerbated by senescence and how they can be alleviated through retardation of cellular aging. Topics discussed include neurodegenerative disease, protein oxidation, cerebrovascular disease, particle-induced inflammation and cardiovascular disease, Alzheimer's disease, ovarian aging, dietary and endogenous anti-oxidants in management of Parkinson's disease, and effects of exercise on oxidation and inflammation. The nineteen expertly authored chapters are organized into three sections in order to present a complete picture to the reader: Age Related Cellular Events, Role of Inflammatory and Oxidative Processes in Age-Related Diseases, and Retardation of Cellular Aging. Inflammation, Oxidative Stress and Age-Related Disease draws from a variety of international perspectives and provides a comprehensive overview of the relationship between disease, cell aging, and oxidative stress, as well as potential for preventing or slowing these processes. This installment of Springer's Oxidative Stress in Applied Basic Research and Clinical Practice is ideal for researchers, clinicians, and advanced graduate students in the fields of cardiology, neuroscience, biogerontolgy, and cell biology.

DDDDDDDDDDDD Effective management logically follows accurate diagnosis. Such logic often is difficult to apply in practice. Absolute diagnostic accuracy may not be possible, particularly in the field of primary care, when management has to be on analyis of symptoms and on knowledge of the individual patient and family. This series follows that on Problems in Practice which was concerned more with diagnosis in the widest sense and this series deals more defini tively with general care and specific treatment of symptoms and diseases. Good management must include knowledge of the nature, course and outcome of the conditions, as well as prominent clinical features and as sessment and investigations, but the emphasis is on what to do best for the patient. Family medical practitioners have particular difficulties and advantages in their work. Because they often work in professional islation in the com munity and deal with relatively small numbers of near-normal patients their experience with the more serious and more rare conditions is restricted. They find it difficult to remain up-to-date with medical advances and even more difficult to decide on the suitability and application of new and rela tively untried methods compared with those that are 'old' and well proven. Their advantages are that because of long-term continuous care for their patients they have come to know them and their families well and are able to become familiar with the more common and less serious diseases of their communities."

This clear-sighted volume introduces the concept of "disruptive cooperation"- transformative partnerships between the health and technology sectors to eliminate widespread healthcare problems such as inequities, waste, and inappropriate care. Emphasizing the most pressing issues of a world growing older with long-term chronic illness, it unveils a new framework for personalized, integrative service based in mobile technologies. Coverage analyzes social aspects of illness and health, clinically robust uses of health data, and wireless and wearable applications in intervention, prevention, and health promotion. And case studies from digital health innovators illustrate opportunities for coordinating the service delivery, business, research/science, and policy sectors to promote healthier aging worldwide. Included among the topics: Cooperation in aging services technologies The quantified self, wearables, and the tracking revolution Smart healthy cities: public-private partnerships Beyond silos to data analytics for population health Cooperation for building secure standards for health data Peer-to-peer platforms for physicians in underserved areas: a human rights approach to social media in medicine Disruptive Cooperation in Digital Health will energize digital health and healthcare professionals in both non-profit and for-profit settings. Policymakers and public health professionals with an interest in innovation policy should find it an inspiring ideabook.

This book brings together in one volume the current state of ageing research in the nematode Caenorhabditis elegans. The authors are leading researchers in the field, placing this topic in the context of human ageing, describing how and why basic discoveries in this simple organism have impacted our prospects for intervention in the ageing process. The authors cover a broad range of topics with regards to organismal and reproductive ageing including anatomical, physiological and biochemical changes, as well as genetic and environmental interventions that promote longevity and ameliorate age-related disease. Ageing is the single most important factor determining the onset of human disease in developed countries. With current worldwide demographic trends indicating that the number of individuals over the age of 65 will continue to rise, it is clear that an understanding of the processes that underpin ageing and age-related disease represents a key challenge in the biomedical sciences. In recent years there have been huge advances in our understanding of the ageing process and many of these have stemmed from genetic analysis of C. elegans. With no analogous book in this subject area this work will be of interest to a wide audience, ranging from academic researchers to the general public.

This newly expanded and updated fifth edition will be the largest and most comprehensive of the five editions and new topics and chapter authors have been added. The authors have created the most comprehensive and up-to-date review of the nutritional strategies available for the prevention of disease and the promotion of health through nutrition. Patients are looking for credible information from their health care providers about a whole range of subjects covered here, including ss-carotene, lycopene, antioxidants, folate, and the myriad of bioactive phytochemicals found in garlic and other foods. With sections on cardiovascular disease, diabetes, and pregnancy among many others, this volume will be of great value to practicing health professionals, including physicians, nutritionists, dentists, pharmacists, dieticians, health educators, policy makers, health economists, regulatory agencies and research investigators. An entire section covers nutrition transitions around the world including Eastern Europe, Latin America and Asia as well as goals for preventive nutrition in developing countries. Preventive Nutrition: The Comprehensive Guide for Health Professionals, 5th Ed. is an important resource for thousands of health professionals who have been utilizing the previous editions since 1997.

This book aims to address the major aspects of future drug product development and therapy for older adults, giving practical guidance for the rational product and clinical development and prescribing of drug products to this ever growing segment of the population. With authors coming from key "aging" markets such as Europe, the USA, China and Japan, the book will provide valuable information for students, scientists, regulators, practitioners, and other healthcare professionals from academia, industry and regulatory bodies.

Published in collaboration with American Journal of Therapeutics, Therapeutic Advances in Hospital Medicine: Focus on the Older Adult is a concise, practical reference that helps you provide optimal care to geriatric patients in the hospital setting. Ideal for hospitalists, geriatricians, nurse practitioners, and physician assistants, this easy-to-read monograph presents expert advice on effectively managing common conditions seen in this growing patient population. Discusses common geriatric hospital presentations such as congestive heart failure, complicated urinary tract infections, symptomatic hyponatremia, orthostatic hypotension, delirium, chronic pain, and insomnia. Includes a section on medication management that addresses the issues of overdose and conflicting prescriptions that arise from multiple medical conditions. Highlights important therapeutic advances in caring for patients with anticoagulant-induced bleeding and diabetes. Covers improved interdisciplinary collaboration for perioperative care, nutritional support, and advanced care planning. Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

This book approaches the concept of adjustment to aging and endeavors to build reader understanding of this construct through a critical review and discussion. Once the reader understands the origins and nature of adjustment to aging, a second innovation encompasses the development of a proposed empirical model of adjustment to aging and the analysis of its components and correlates. Measures to assess adjustment to aging, policies, programs and interventions comprising adjustment to aging and its components and correlates will also be addressed. Another innovation includes the multidimensional experience of adjustment to aging from the cultural perspective. Lastly, it addresses areas of future development related to this construct.Future policies and interventions in older populations need to integrate and debate the role of adjustment to aging, and ultimately consider a variety of different strategies, each with a different set of costs and benefits. Health and social professionals will be at the vanguard of policy making and community and institutional interventions. Hence, resources and tools to adequately prepare these individuals for the future years will be vital. It is the author's hope that this resource can be valuable for professionals and students working within the field of aging, as they develop research and intervention policies encompassing adjustment to aging in the coming years.