Current Challenges and Management of Disease in the Elderly Population is a comprehensive insight into the diseases and their management in elderly population during ageing. The book provides information on the development in understanding, diagnosis and management of major diseases through biological and technological interventions. Non-communicable diseases currently infesting old age population will have a huge epidemiological burden on the health care system in near future. Middle- and high-income countries warrant sincere efforts to provide information on the current challenges and management of disease in elderly population in health care professionals and social organizations related to the health of society. The book is a holistic approach by international authors from different fields on major diseases, which are predominantly increasing at an alarming rate in old age population around the globe. The first chapter provides information on stem cells involved in the regulation of cell homeostasis by process of DNA-based methylation/demethylation and regulating gene expression involved in cell fate to undergo apoptosis. The second chapter emphasizes the immunological decline in innate and adaptive immunity in ageing cells, which leads to decreased activity of T-cell and T-regulatory cells. The third, fourth and fifth chapters deal with chronic diseases like Type 2 Diabetes mellitus based neuropathy, different bone diseases in old age and involvement of Vitamin D in women's bone health in elderly population. The problem of Type 2 Diabetes mellitus based neuropathy is the result of unattended or poor medical interventions, therefore emphasis on this problem and its prevention is dealt with in detail. Further disease like osteoporosis, Paget disease, and Arthritis, which are very common in old age population and deficiency of Vitamin D, calcium, phosphorous in elderly women after menopause, where estrogen based hormonal deabsorbtion of Vitamin D lead to poor bone health, is detailed from mechanism, diagnosis, current challenges and future perspective of preventions. Ageing eye problems and associated challenges are incorporated with in depth information on dry eyes and vitreous detachment, glaucoma, age-related macular degeneration, and diabetic retinopathy, which leads to irreversible visual impairment or blindness, the details information on detection, treatment and prevention are discussed in Chapter 6. The task of detecting specific diseases is paramount for the treatment of neurodegenerative disease. Chapter 7 & 8 on biomarkers using omics technology and metalobomics provides complete information on the recent development in identification and analysis of metabolites and biomolecules using different technology platforms to detect the disease condition at an early stage. They also highlight challenges in the field that need to be addressed to overcome the problem of disease diagnosis for timely intervention. The majority of neurodegenerative disorders influencing the population above the age of 65 is mainly related to neurodegeneration and oxidative stress. Tthe last two chapters, 9 &10, of this book have tried to provide information related to mechanism of neurodegeneration in various neuronal disorders and the role of various plant flavanoids in prevention of disease onset, the effect on the choice of nutraceuticals and their role in brain heath and prevention from old age neuronal problems.

This updated edition carries on the tradition of providing sound and practical guidance for new and experienced practitioners on all aspects of food and nourishment for ageing adults. Whether residing at home, in assisted living or in a nursing facility, older adults have unique nutrition needs. Like the previous edition, this hands-on reference encompasses the total perspective on person-driven nutrition care of older adults, from nutrition and disease states to regulatory compliance in health care settings. Among the many timely updates addressed in this edition are: Strategies for implementing the updated Nutrition Care Process. Understanding and developing systems to implement quality assurance and performance improvement. Changes in Medicare and health-care reform resulting from the Affordable Care Act are addressed. A new section on emergency preparedness - and an important addition that reinforces the need for practitioners to develop a plan for maintaining care during an emergency or disaster.

A wide variety of ambitions and measures to slow, stop, and reverse phenomena associated with aging have been part of human culture since early civilization. From alchemy to cell injections to dietary supplements, the list of techniques aimed at altering the processes of aging continues to expand. Charlatans, quacks, and entrpreneurs proffering anti-aging products and practices have always exploited uniformed customers and instilled doubt and apprehension toward practices intended to extend life. Recently, however, the pursuit of longevity has developed into a respectable scientific activity. Many biologists are substantially funded by the government and the private sector to conduct research that they believe will lead to effective anti-aging interventions.
While many embrace this quest for "prolongevity"--extended youth and long life--others fear its consequences. If effective anti-aging interventions were achieved, they would likely bring about profound alterations in the experiences of individual and collective life. What if aging could be decelerated to the extent that both average life expectancy and maximum life span would increase by forty percent? What if all humans could live to be centenarians, free of the chronic diseases and disabilities now commonly associated with old age? What if modern scientists could find the modern equivalent to the Fountain of Youth that Ponce de Leon sought?
This book addresses these questions by exploring the ramifications of possible anti-aging interventions on both individual and collective life. Through a series of essays, it examines the biomedical goal of prolongevity from cultural, scientific, religious, and ethical perspectives, offering a sweeping view into the future of aging.

Why do we age? Is aging inevitable? Will advances in medical knowledge allow us to extend the human lifespan beyond its present limits? Because growing old has long been the one irreducible reality of human existence, these intriguing questions arise more often in the context of science fiction than science fact. But recent discoveries in the fields of cell biology and molecular genetics are seriously challenging the assumption that human lifespans are beyond our control. With such discoveries in mind, noted cell biologist William R. Clark clearly and skillfully describes how senescence begins at the level of individual cells and how cellular replication may be bound up with aging of the entire organism. He explores the evolutionary origin and function of aging, the cellular connections between aging and cancer, the parallels between cellular senescence and Alzheimer's disease, and the insights gained through studying human genetic disorders--such as Werner's syndrome--that mimic the symptoms of aging. Clark also explains how reduction in caloric intake may actually help increase lifespan, and how the destructive effects of oxidative elements in the body may be limited by the consumption of antioxidants found in fruits and vegetables. In a final chapter, Clark considers the social and economic aspects of living longer, the implications of gene therapy on senescence, and what we might learn about aging from experiments in cloning. This is a highly readable, provocative account of some of the most far-reaching and controversial questions we are likely to ask in the next century.

Sie halten dieses Buch in den Handen, weil fur Sie persoenlich Fitness, oder das Altern an sich ein Thema sind. Vielleicht haben Sie sich schon mit Hilfe von Buchern, Kursen, oder auch persoenlicher Beratung Unterstutzung gesucht, wenn es darum ging, Ihr persoenliches Wohlbefinden, Ihre Belastbarkeit, oder einfach die Lebensqualitat in der kommenden Zeit zu verbessern. Das bedeutet, dass Ihr Interesse an den modernen und wissenschaftlich begrundeten Methoden, gesund und fit ins Alter zu wachsen, gross genug ist, um dieses Buch zu lesen. Ganz gleich, wie alt Sie sind, wenn Sie koerperlich inaktiv, vielleicht etwas ub- gewichtig sind, einen oder mehrere Risikofaktoren fur Zivilisationserkrankungen aufweisen, hier finden Sie Loesungen fur einen Weg zur Besserung Ihres Zustandes. Sind Sie vielleicht schon chronisch von einer dieser Erkrankungen betroffen dann wird dieses Buch eine Unterstutzung sein. Je untrainierter Sie sind, desto mehr werden Sie von diesem Buch profitieren, da es Ihnen Stra- gien zur Wiedererlangung bzw. Festigung der Gesundheit im Rahmen eines gesunden und erlebnisreichen Alterns aufzeigt. Auch wenn Sie regelmassig koerperlich aktiv sind, joggen, schwimmen, be- steigen, Ski fahren und Tennis spielen, und sich nach Ihrer Pensionierung noch einmal ein grosses "Erlebnis" goennen wollen, wie z.B. den Kailash zu umrunden, einige 4000er zu bezwingen, einen Marathon zu laufen oder Helikopter Ski fahren zu gehen - auch dann sollten Sie in diesem Buch blattern, da auch die wichtigsten Grundlagen fur eine gezielte Leistungssteigerung vermittelt werden.

Gerontological nursing remains a critical specialty area for the profession of nursing, especially as the older adult population grows. The Fifth Edition of Gerontological Nursing: Competencies for Care takes a holistic approach and teaches students how to provide quality patient care for the older adult, preparing them to effectively care for this population. Students and faculty appreciate the practical approach as well as the author's logical organization of competency-based content both of which are a hallmark of this text. Following the framework outlined by the AACN's recommended baccalaureate competencies and curricular guidelines for the care of older adults, the text guides students through the core foundations of gerontological nursing as a specialty. The Fifth Edition emphasizes these essential competencies coupled with the management of geriatric syndromes that impact this population including falls, sleep disorders, depression/anxiety, and elder abuse. Key Features: * Practical information on dementia for nurses and caregivers * Expanded content on fall prevention * New content on COVID-19 and telehealth care * "Healthy Aging Tips" found throughout the text * Updated research highlights * Critical thinking and personal reflection exercises * Video case studies in the form of author-conducted interviews accessible via Navigate Premier Access

One of the largest patient populations seen by neuropsychologists are older adults suffering from problems associated with aging. Further, the proportion of the population aged 65 and above is rising rapidly. This book provides a guide to neuropsychological clinicians increasingly called upon to assess this population. The book details in a step-by-step fashion the phases and considerations in performing a neuropsychological assessment of an older patient. It covers procedural details including review of patient's medical records, clinical interview, formal testing, interpretation of test scores, addressing referral questions, and preparing an evaluation report.
Key Features
* Outlines a clear, logical approach to neuropsychological evaluation
* Provides specific clinical practice guidelines for each phase of the evaluation
* Integrates clinical practice with up-to-date research findings
* Recommends specific tests for evaluating older adults
* Details how to interpret test findings and identify the patient's neuropsychological profile
* Illustrates important points with examples and case materials, many neuropathologically-confirmed
* Includes forms useful in clinical practice

This volume presents a series of case narratives, following individual patients and families throughout the course of illness and death in the context of hospice and palliative care. Using a variety of qualitative research methods, including participant-observation, interviews, and journal-keeping, the experiences, perceptions, and feelings of the patient, the family and a range of caregivers are recorded, providing the reader with rich, multi-textured narratives. Going beyond conventional case reports in Medicine, typically concentrating on symptoms and treatment, these narratives depict how individuals find personal meaning in illness, and how this influences the experience and outcome of care.

We live in an ageing society, where people are living longer, and where decreases in the birth rate mean that the proportion of the population above retirement age is steadily increasing. An ageing population has considerable implications for health services and care provision. Consequently there is a growing interest among researchers, medical practitioners, and policy makers in older adults, their capabilities, and the changes in their cognitive functioning. This book offers an up-to-the-minute account of the latest methodological and theoretical issues in cognitive ageing. Part of the Debates in Psychology series, it sets out the arguments surrounding the currently controversial questions in cognitive ageing. What is the appropriate methodology for understanding cognitive change? How many factors are necessary to understand the patterns of age-related change? What might these factors be? The topics and arguments are explored in a series of chapters by the leading researchers in the field. Each contributor offers their view of how cognitive ageing can be best understood, and together they cover a broad range of cognitive functions including language use, cognitive slowing, and memory loss. Each of the chapters stands alone as the latest review of work in the area. Taken together, the chapters form a coherent theoretical debate through which the reader will learn about the dynamic nature of cognitive ageing research, and about the direction this research will be taking in the future. Models of Cognitive Aging will be an invaluable resource for anyone with an interest in the elderly, and in their cognitive abilities.

This book serves as a comprehensive reference for the basic principles of caring for older adults, directly corresponding to the key competencies for medical student and residents. These competencies are covered in 10 sections, each with chapters that target the skills and knowledge necessary for achieving competency. Each of the 45 chapters follow a consistent format for ease of use, beginning with an introduction to the associated competency and concluding with the most salient points for mastery. Chapters also includes brief cases to provide context to the clinical reasoning behind the competency, strengthening the core understanding necessary to physicians of the future. Written by expert educators and clinicians in geriatric medicine, Geriatric Practice is key resource for students in geriatric medicine, family and internal medicine, specialties, hospice and nursing home training, and all clinicians studying to work with aging patients.

There is a near-universal folk saying that everyone wishes to live a good long life, but no one wishes for old age. More contemporarily, the rock and roll band, Little Feat, sang, "You know that you're over the hill when your mind's making promises your body can't fill. " This book is about the good long life. It is a book about primary prevention strategies in the aging process; it is not about preventing that process. It is not about being old. Instead, it is about the things that individuals - and the helping professionals who provide them with counsel and assistance - can do to prevent the preventable problems of advancing age, and to better manage those changes in functioning that cannot be prevented. In short, it is about extending all our capacities to the fullest so that we can better keep all those promises that we make to ourselves and others. Aging is a life-long process. We focus here on the changes that are taking place in our selves and in our society as we age. In particular, we focus on what we can do to affect these changes by the choices we make and how we live. This book offers primary prevention strategies for mature and older adults, with the recognition that mature adulthood starts as soon as we are old enough to truly appreciate our active role in our own aging processes.

This text highlights good practice in elderly care and identifies useful approaches, with examples of where these exist. There is consideration of issues involved in the new Community Care Act, especially the assessment of need and access to services. The overall empha sis is on the quality of health care, the relevant contributions of clinical audit, and other quality assurance initiatives.;It should be of interest to geriatricians and other staff involved in health care of the elderly.

This unique book looks at the biology of aging from a fundamentally new perspective, one based on evolutionary theory rather than traditional concepts which emphasize molecular and cellular processes. The basis for this approach lies in the fact that natural selection, as a powerful determining force, tends to decline in importance with age. Many of the characteristics we associate with aging, the author argues, are more the result of this decline than any mechanical imperative contained within organic structures. This theory in turn yields the most fruitful avenues for seeking answers to the problem of aging, and should be recognized as the intellectual core of gerontology and the foundation for future research. The author ably surveys the vast literature on aging, presenting mathematical, experimental, and comparative findings to illustrate and support the central thesis. The result is the first complete synthesis of this vital field. Evolutionary biologists, gerontologists, and all those concerned with the science of aging will find it a stimulating, strongly argued account.

It is increasingly important for physicians who treat older persons, and for researchers on aging, to understand how molecular biology informs clinical expressions of aging and age-related conditions such as osteoporosis, diabetes, osteoarthritis, frailty, cancer, and dementia. Dr. David Hamerman translates basic scientific concepts into precepts of clinical practice and sheds light on the links among biology, natural aging, longevity, and disease.

Exploring the connections between disease and the science behind it, Geriatric Bioscience addresses how mechanisms of inflammation, cytokine expression, and stress responses influence disease and how preventive gerontology in the practice of medicine could compress morbidity. Hamerman also discusses cutting-edge therapies such as cyclo-oxygenases, bisphosphonates, statins, cytokine inhibitors, and hormone therapies.

Examining the science of geriatrics and converting its concepts into clinical applications, this groundbreaking work provides clinicians and researchers with a solid foundation for a greater understanding of the diagnosis, treatment, and prevention of age-related diseases as well as recommendations for promoting healthy aging.

The realities and misconceptions of long-term care and the challenges it presents for the ethics of autonomy are analyzed in this perceptive work. While defending the concept of autonomy, the author argues that the standard view of autonomy as non-interference and independence has only a limited applicability for long-term care. He explains that autonomy should be understood as a comprehensiveness that defines the overall course of a person's life rather than as a way of responding to an isolated situation. Agich distinguishes actual and ideal autonomy and argues that actual autonomy is better revealed in the everyday experiences of long-term care than in dramatic, conflict-ridden paradigm situations such as decisions to institutionalize, to initiate aggressive treatments, or to withhold or to withdraw life-sustaining treatments. Through a phenomenological analysis of long-term care, he develops an ethical framework for it by showing how autonomy is actually manifest in certain structural features of the social world of long-term care. Throughout this timely work, the rich sociological and anthropological literature on aging and long-term care is referenced and the practical ethical questions of promoting and enhancing the exercise of autonomy are addressed.

In few places in American society are adults so dependent on others as in nursing homes. Minimizing this dependency and promoting autonomy has become a major focus of policy and ethics in gerontology. Yet most of these discussions are divorced from the day-to-day reality of long-term care and are implicitly based on concepts of autonomy derived from acute medical care settings. Promoting autonomy in long-term care, however, is a complex task which requires close attention to everyday routines and a fundamental rethinking of the meaning of autonomy.
This timely work is based on an observational study of two different types of settings which provide long-term care for the elderly. The authors offer a detailed description of the organizational patterns that erode autonomy of the elderly. Their observations lead to a substantial rethinking of what the concept of autonomy means in these settings. The book concludes with concrete suggestions on methods to increase the autonomy of elderly individuals in long-term care institutions.

A text for upper-undergraduate and graduate courses in physical activity and aging or gerontology; also a reference for physical activity instructors, fitness specialists, personal trainers, activity directors, activity assistants, and therapeutic recreation specialists working with older adults.

This title is directed primarily towards health care professionals outside of the United States. Dr. Menz uses his detailed and extensive knowledge of the subject to provide a critique of the strengths and limitations of existing literature and to present in this easy-to-access volume a thoroughly practical, clinically orientated and evidence-based guide. The book provides a comprehensive guide to the assessment and management of foot and ankle problems in the elderly and older people. Areas covered include the epidemiology of foot problems, functional implications, assessment of the older person with foot problems, common foot problems and their management, foot and ankle manifestations of common systemic conditions, wound management, footwear and orthotic considerations, surgical considerations and outcome assessment. Each chapter provides a comprehensive and critical review of the literature as well as providing practical evidence-based guidelines for clinicians.
"This book is packed full of a wide variety of references from peer-reviewed papers in each chapter. The author Hylton Menz, has obviously taken a clear evidence-based approach to every aspect of the book, which makes it an invaluable tool for podiatrists & podiatry students. I am sure that clinicians such as physiotherapists (& students) will find this book useful. I myself am a podiatry student & am certain I will use this book for the rest of my course, once qualified & beyond. chapters 1 & 2 give a great explanation of the prevalence of foot problems & physiological changes of ageing, which is useful in all aspects of podiatry i.e.; biomechanics- physiological changes in muscle mass etc. The diagrams & tables are a fantastic compilation of relevant information which provide a useful summary of the text; physiological changes of skin, muscle, bone etc & their effects & wound classification to name a couple. Nail, skin & vascular conditions are covered well with some fantastic colour pictures. I am really enjoying reading this book, having learnt a lot from it already. I recommend this as an essential read for podiatrists, students & any healthcare professionals involved in working with the older patient."
- Nicola Agget, Podiatry Student, University of Plymouth

Psychotherapy in Later Life is a practical how-to-guide for psychiatrists, psychologists and mental health workers on choosing and delivering evidence-based psychological therapies to older adults. It covers all the main evidence-based psychological therapies such as cognitive behavioural therapy (CBT) and interpersonal psychotherapy (IPT), as well as specialist topics such as combining psychotherapy with pharmacological treatments, working with diverse populations and individual versus group therapy. The World Health Organization estimates that over the next four decades, the proportion of the world's older adults will nearly double, from twelve percent to twenty-two percent, and that one in five older adults has a diagnosable mental health disorder. Given the increasing number of older adults requiring mental health treatment, incorporating talking therapies into treatment plans is key to tackling issues related to polypharmacy, medication interactions and side effects. Written by experts in geriatric mental health, this book provides the most authoritative information on the use of psychotherapy in older adults.

The Oxford Textbook of Old Age Psychiatry, Third Edition, has been thoroughly updated to keep pace with the developments that have taken place in old age psychiatry since publication of the Second Edition in 2013, including the publication of the DSM-5/ICD-11 classification criteria. The Third Edition also includes new chapters on the ageing brain; the experience of dementia; carers' issues; biomarkers; and old age psychiatry in low- and middle-income countries. This new edition introduces two new co-editors, Robert Stewart, Professor of Psychiatric Epidemiology & Clinical Informatics at King's College London (and a Co-Editor of Practical Psychiatric Epidemiology), and John-Paul Taylor, Professor of Translational Dementia Research at Newcastle University. Part of the authoritative Oxford Textbooks in Psychiatry series, this comprehensive resource is an essential reference for old age psychiatrists, geriatricians, and other clinicians who are interested in the mental health care of older people.

A history of aging in America surveys and compares actualities and attitudes in the eighteenth, nineteenth, and twentieth centuries and suggests practical improvements on the current inadequate system of pensions, social security, medicare, and other programs.

In the 21st century, people in the developed world are living longer. They hope they will have a healthy longer life and then die relatively quickly and peacefully. But frequently that does not happen. While people are living healthy a little longer, they tend to live sick for a lot longer. And at the end of being sick before dying, they and their families are frequently faced with daunting decisions about whether to continue life prolonging medical treatments or whether to find meaningful and forthright ways to die more easily and quickly. In this context, some people are searching for more and better options to hasten death. They may be experiencing unacceptable suffering in the present or may fear it in the near future. But they do not know the full range of options legally available to them. Voluntary stopping eating and drinking (VSED), though relatively unknown and poorly understood, is a widely available option for hastening death. VSED is legally permitted in places where medical assistance in dying (MAID) is not. And unlike U.S. jurisdictions where MAID is legally permitted, VSED is not limited to terminal illness or to those with current decision-making capacity. VSED is a compassionate option that respects patient choice. Despite its strongly misleading image of starvation, death by VSED is typically peaceful and meaningful when accompanied by adequate clinician and/or caregiver support. Moreover, the practice is not limited to avoiding unbearable suffering, but may also be used by those who are determined to avoid living with unacceptable deterioration such as severe dementia. But VSED is "not for everyone." This volume provides a realistic, appropriately critical, yet supportive assessment of the practice. Eight illustrative, previously unpublished real cases are included, receiving pragmatic analysis in each chapter. The volume's integrated, multi-professional, multi-disciplinary character makes it useful for a wide range of readers: patients considering present or future end-of-life options and their families, clinicians of all kinds, ethicists, lawyers, and institutional administrators. Appendices include recommended elements of an advance directive for stopping eating and drinking in one's future if and when decision making capacity is lost, and what to record as cause of death on the death certificates of those who hasten death by VSED.

Erstmals im deutschsprachigen Raum wird die Lebenswirklichkeit von Menschen, deren AElterwerden mit gesundheitlichen und gesellschaftlichen Stigmata verbunden ist, systematisch in den Blick genommen. Menschen mit Migrationshintergrund oder Behinderung, mit chronischen Erkrankungen wie HIV/Aids, mit langjahriger Drogen- oder Psychoseerfahrung, schwul, lesbisch oder trans* lebende Menschen weisen im Alter aufgrund ihrer Zugehoerigkeit zu einer stigmatisierten Gruppe spezifische psychosoziale Bedarfe auf. In dem Sammelband werden diese Bedarfe anhand aktueller Forschungs- und Praxisbefunde adressiert und innovative Perspektiven eines selbstbestimmten Alterns aufgezeigt.