With the establishment of new international standards for environmental management systems (EMS), many managers are faced with the daunting and often bewildering task of creating management systems that enable their companies to conform to these standards. In their haste and confusion, however, many companies implement bureaucratic, ineffective systems that add no real value to their businesses.

The ISO 14001 Implementation Guide: Creating an Integrated Management System shows you how to use the ISO 14001 standard to improve your company's productivity and profitability while meeting registration requirements. Using a practical, business-oriented approach, this authoritative book details the background and development of the ISO 14000 series of standards, fully explains the requirements of 14001, and offers hands-on guidance on how to implement an effective EMS. It highlights common but costly mistakes, and leads you step-by-step through the creation of an EMS that will result in a more competitive business as well as a cleaner environment.

Suzan L. Jackson draws on her experience as an ISO 9000 and ISO 14000 consultant and trainer and as a member of the U.S. Technical Advisory Group to ISO Technical Committee 207, which is developing the ISO 14000 environmental management standards. With her insider's perspective, Jackson demonstrates how the implementation of a cohesive, well-defined management system helps cut costs, increase efficiency, and focus energies. In addition, she provides insights into ways of successfully integrating ISO 9000, ISO 14001, and other management systems.

The ISO 14001 Implementation Guide provides a wealth of proven tips, techniques, and tools that help ensure smooth, trouble-free, and efficient EMS implementation, including critical success factors, flowcharts for setting up the elements of an environmental management system, helpful tips, and advice for avoiding common pitfalls.

With its timely, straightforward, and on-target advice, The ISO 14001 Implementation Guide is the definitive, practical guide for environmental and quality professionals and managers who need to develop an environmental management system that will improve business as well as meet the ISO 14001 standard.

"An excellent, and very readable workbook on how to integrate management systems into an organization. ISO 14001 will be an important, but difficult, step into the future for much of U.S. industry—this book should be close at hand for those taking that step."—Dorothy P. Bowers, Vice President, Environmental and Safety Policy , Merck & Co., Inc.

"Suzan Jackson's book provides vital guidance and answers. . . . Her book can be quite helpful to those who are considering establishing a new environmental management system, or those who just want a better understanding of ISO 14001."—John Master, Former Director, Environmental, Health and Safety , ARCO Chemical Co.

"A remarkably easy-to-read, highly authoritative guide to a very complex standard. Suzan Jackson shows us how environmental management and business ,improvement are no longer mutually exclusive goals." —Robin Gildersleeve, President, INFORM (International Forum for Management Systems, Inc.)

Written by a recognized ISO expert and member of the U.S. Technical Advisory Group to ISO Technical Committee 207, which is preparing the ISO 14000 environmental management standard, this invaluable guide shows you how to:

• Learn to use an environmental management system to improve the overall effectiveness and profitability of the company.
• Meet the requirements of ISO 14001.
• Develop and implement a cohesive, well-defined environmental management system.
• Integrate an EMS with other management systems.
• Formulate an environmental policy and draw up strategic plans and objectives for your company.
• Monitor and measure the effectiveness of the system, keep records, and take preventive and corrective action.

This book introduces the applications of Industry 4.0 in machine tools through an overview of the latest available digital technologies. It focuses on digital twining, communication between industrial controls, motion, and input/output devices, along with sustainability in SMEs. Machine Tools: An Industry 4.0 Perspective focuses on the digital twining of machine tools, which improves the life of the machines and provides a method of operating a factory during times of complete lockdown resulting from various conditions. It presents an overview of the communication between industrial controls, motion, and input/output devices through standardized digital interfaces such as SERCOS and USB. The book goes on to discuss industrial cybersecurity systems applicable to discrete manufacturing, which includes cyberattacks and human errors, and address the security aspects related to software, hardware, and data. The book also explores the application of big data for different stages of production and illustrates the uses such as predictive maintenance, product quality, product life cycle management (PLM), and more. This book is an ideal reference for undergraduate, graduate, and postgraduate students of industrial, mechanical, and mechatronics engineering, along with professionals, and general readers.

This book is the definitive work on the theory and practice of pharmaceutical tablet and pellet coating. It describes both the practical and theoretical aspects of tablet coating, including the equipment and methods used in laboratory development, scale-up and production systems, More...as well as automation and validation. This book also discusses the problems of conforming to world-wide regulations, and the hazards of environmental pollution.

This book analyses the determining factors behind productivity and innovation amongst Small and Medium Enterprises (SMEs) in Singapore, and within the context of South East Asia, in order to offer recommendations for increasing productivity and aiding economic growth. SME firms are an influential driver of economic growth in advanced world economies like the USA, Germany, Japan and South Korea. Throughout the 2000s, Singapore experienced a decline in economic growth which was linked to decreasing productivity in its SMEs. The decline triggered a transformational policy by a Government intent on forging a 'high skill-high productivity' future. Given substantial evidence that low productivity growth occurred in sectors where immigrants dominated the workforce, the seeds of recovery focused on improving productivity and innovation amongst SMEs in those sectors. Hence, this book investigates the factors determining productivity amongst SMEs across the manufacturing sector. It utilises personal interviews with global experts and CEOs, combined with primary data collected from a major international Delphi survey, and interviews with 215 SME owners and managers in Singapore. This data helps us to better understand how these productivity-enhancing factors can be used to increase performance amongst SMEs. By investigating the nature and process of total factor productivity in Singapore's SMEs, this book tells the policy story behind the revolution. To provide a comparative analysis, Singapore's story is placed within a South East Asian context. The unfolding narrative contains important lessons for policy makers and industry globally, as they assess the strategic choices available to them for improving productivity and innovation. This book will be of great interest to students and scholars of innovation and productivity, as well as economic development officers, government policy advisors, SME business managers and sustainable businesses.

When a biological drug patent expires, alternative biosimilar products are developed. The development of biosimilar products is complicated and involves numerous considerations and steps. The assessment of biosimilarity and interchangeability is also complicated and difficult. Biosimilar Drug Product Development presents current issues for the development of biosimilars and gives detailed reviews of its various stages and contributing factors as well as relevant regulatory pathways and pre- and post-approval issues.

The properties of woven and knitted fabrics differ largely due to the path yarn follows in the fabric structure. This path determines the fabric's physical properties, mechanical properties, and appearance. A slight variation to the design may result in entirely different properties for the fabric. Structural Textile Design provides detailed insight on different types of designs used for the production of woven and knitted fabrics, highlighting the effect design has on a fabric's properties and applications. With focus on the techniques used to draw designs and produce them on weaving and knitting machines, this book will be of great interest to textile engineers, professionals and graduate students in textile technology and manufacturing.

The process of development in recent times has been characteristically marked by the expanding reach of multinational enterprises, flows of foreign direct investment, unprecedented growth of information and communication technologies (ICT) and knowledge-based industries, and infusion of ICT across the entire spectrum of industries and activities. High-tech knowledge-based industries like information technology, biotechnology, pharmaceuticals and so on have played an important role in the transition of Chinese and Indian economies the two largest and fastest growing economies.

This inter-disciplinary book offers an in-depth understanding of the behaviour of firms in these industries, analysing the strategies they adopt in a globally competitive environment, the role they have played in ushering in the growth revolution in China and India, and the contribution they have made to the nature and growth of employment. This study also dwells upon the emerging nature of scientific and technological developments like nanotechnology, novel materials, spintronics and quantum computers, with the conclusion that in the future, knowledge and technology are going to be the real sources of wealth for nations.

The relationship between trade policy and economic performance is one of the oldest controversies in economic development. In recent years, there has been a revival of interest in the debate on the implications of trade reforms for productivity growth and domestic pricing behaviour due in part to the current phase of wide-spread trade liberalisation in developing countries and in part to developments in economic theory, notably endogenous growth theories and theories of imperfect competition. Also, there has been considerable interest in whether trade reforms can lead to higher wage inequality and regional inequality in developing countries. Both in academic and policy arenas the interest in international trade as a powerful positive force for reducing poverty in low-income countries has increased. In this book, the author examines the implications of trade reforms with specific reference to the Indian manufacturing sector. In particular, it explores the evolution of regional and wage inequality, employment, productivity and prices from the import substitution phase of the 1970s to the period of radical reforms of the 1990s. The strength of the book is the careful and systematic examination of the various aspects of the trade-development nexus using rigorous empirical methods and a detailed data-set of Indian industries from 1975 to 2000. Economists in general and South Asian scholars in particular will find this thorough study interesting and useful.

Freeze-drying, in the past popular in the food industry, has more recently been adopted by the pharmaceutical industry as a standard method for the production of stable solid preparations. Freeze-drying of Pharmaceuticals and Biopharmaceuticals is the first book to specifically describe this process, as related to the pharmaceutical industry. The emphasis of this book is on the properties of the materials processed, how effective formulations are arrived at, and how they are stored and marketed. Beginning with a historical overview of the process, Freeze-drying of Pharmaceuticals and Biopharmaceuticals briefly describes the processes and equipment involved, including: the physics, chemistry and biochemistry associated with freezing, aspects of formulation development, primary and secondary drying; the economics and engineering of scaling up; and, most importantly, attributes of the dried product. It also discusses in detail the science behind freeze-drying, such as the properties of crystalline and amorphous solids. The book concludes with selected case studies and discusses the future of freeze-drying, advances in alternative drying methods, and concludes with an extensive bibliography. This book, written by a leading expert in the field, is aimed primarily at product and process developers in the biopharmaceutical industry and academia.

Encompassing the full spectrum of project management s role and responsibility encountered in the pharmaceutical industry, Pharmaceutical Project Management outlines the key objectives, risks, and challenges of each stage of the pharmaceutical lifecycle, from discovery and preclinical phases through clinical development, manufacturing, registration, and launch.

New updated material includes:

• expert recommendations and informative articles on decision-making
• planning principles and planning systems
• management of subcontracted development
• manufacturing project management
• team leadership and skill sets
• drug development strategies

It covers primary project management objectives, functions, and descriptions of the nature and execution of work activities in a clear and reader-friendly format to illustrate key characteristics and objectives, assist managers in projecting the risks and challenges of each development option, and supply concise recommendations for successful project planning.

This work examines the roles that American businesses and photojournalists played in the early overseas marketing of the Japanese??????built Nikon camera and its Nikkor optics between 1946 and 1951. Particular attention is paid to the San Francisco??????based Overseas Finance and Trading Company, which was the major U.S. importer of Nikon products between 1949 and 1953. The work also details the roles of Overseas Finance leaders Hans Liholm and Adolph Gasser in providing marketing and technical guidance to Nikon in the company's formative years.

This edited volume evaluates recent EU quality policy, focusing on the structure, governance, technical specifications and performances - economic, environmental and social - of Food Quality Schemes (FQS) in the European Union and South East Asia. The intended benefits of FQS include generating a fair return for farmers and producers, and enabling consumers to make better-informed purchasing choices through effective labeling. In addition, policy makers now consider FQS as a means of guaranteeing not only quality in food production, but also sustainability. Despite these potential benefits, the economic performance of the FQS (e.g. PDO, PGI, organic) has been variable. While some support significant value-added production, with substantial benefits to producers, consumers and wider economies, many others have failed to become economically sustainable. In addition, the environmental and social performance of FQS remains largely unexamined, with the exception of the environmental performance of organic products. The editors examine these discrepancies and offer a nuanced evaluation of the effectiveness of such policies. Several unique features make this volume a key resource for those interested in FQS and in the sustainability of food products. The editors provide a concise description of the value chain, the governance and the technical specifications of 27 FQS in Europe and South East Asia. The editors also provide a sustainability assessment of each of these FQS, and support or question the view that FQS are moving from "quality" to "sustainability." Finally, the volume serves as a repository of key data on these FQS. Readers have access to the raw data necessary to compute the indicators used in the sustainability assessment (eg. value added, number of jobs, quantity of fertilizers, etc), allowing them to conduct novel re-analysis. The book is designed for an interdisciplinary audience of academics, policy makers, and stakeholders. The compilation of FQS case studies makes it a useful reference for researchers and students of food policy, geography, food anthropology, local and rural development, local agri-food systems and agri-food chains. Stakeholders such as national and European regulators, entities responsible for FQS technical specifications, and embassy staff will also find the information relevant. Additionally, individuals helping to implement food quality schemes, including auditors, producers, and consumer associates, as well as stakeholders in the sustainability of food products, including farmers, farmer's associations, and environmental NGOs, will also find the information relevant and important for their work.

A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Sixth Edition features the latest research surrounding the application of pharmacology in drug discovery in an effort to equip readers with a deeper understanding of complex and rapid changes in this field. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for anyone involved in drug discovery. This edition has been reorganized for better flow and clarity and includes material on new technologies for screening (virtual, DNA encoded libraires, fragment-based) and a major section on phenotypic (target agnostic) screening for new leads and determination of drug targets. With full color illustrations as well as new examples throughout, this book remains a top reference for all industry and academic scientists and students directly involved in drug discovery or pharmacologic research. New material includes a discussion of the determination of target engagement, including numerous new ways to demonstrate the physical interaction of molecules with drug targets and new drug candidates such a mRNA, gene therapy, antibodies and information on CRISPR and genomics.

There are many remote areas scattered throughout the world where dairy farming is a well-established occupation. Large quantities of highgrade milk can be produced in such areas but the local market cannot always absorb them, especially during peak periods. Converting milk to cheese is one method of dealing with the surplus. Cheesemaking provides an incentive for improving dairying as well as creating new jobs. It also improves the local diet and raises the standard of living generally, through a better understanding of hygiene, scientific techniques and community spirit. Using traditional cheesemaking methods, this book gives an idea of the opportunities that cheesemaking offers as a source of rural employment, and of the problems that will be encountered by anyone planning to start such a business.

This collection of articles includes case studies of attempts to improve small-scale food processing, remembering that "small is beautiful, but difficult." Case studies cover grain and fruit processing, baking, beekeeping, and small-scale oil production.

Despite increasing academic interest in both the study of masculinity and the history of consumption, there are still few published studies that bring together both concerns. By investigating the changing nature of the retailing of menswear, this book illuminates wider aspects of masculine identity as well as patterns of male consumption between the years 1880 and 1939. While previous historical studies of masculinity have focused overwhelmingly on the moral, spiritual and physical characteristics associated with notions of 'manliness', this book considers the relationship between men and activities which were widely considered to be at least potentially 'unmanly' - selling, as well as buying clothes - thus shedding new light on men's lives and identities in this period.

The Silicon Dragon is a systematic study of the growth of high-tech giants in the Greater China Region, depicting the success story of the microelectronics industry in Taiwan. Literature and studies on Taiwan's success are surprisingly limited, and this book aims to fill this gap, addressing questions such as: How has Taiwan achieved such an outstanding performance in the information industry? How did Taiwan obtain and maintain its competitive advantage? What was the secret of success? What role did the government and manufacturers play during the development process? What insights can newcomers gain from these achievements? The book examines the government policies that acted as catalysts to the growth of high-tech industries in Taiwan, along with the roles of high-tech 'incubators' and government-administered science parks. The authors provide case studies of high profile companies including Acer, Philips Semiconductors and Macronix International, and interviews with key decision makers to highlight the corporate strategies adopted in response to government policies and global commercial demand. Finally, insightful narratives on the birth and growth of a government-fostered strategic industry are provided, as is a synopsis of the Asian contribution to the evolution of the global microelectronics development. This book will strongly appeal to academics, researchers and students with an interest in engineering, technology and business management. Business managers and government officials will also find much to interest them in this book.

Written by a leading campaigner for GM Watch, one of the world's leading lobbying groups, this book reveals the huge issues that are at stake. Genetically modified food has been headline news for years, but it's difficult to know how far the genetic revolution has affected our lives. Is the food on our shelves free of genetically engineered ingredients? How much power do food corporations wield? Andy Rees provides the answers. He shows that, while corporations that produce genetically modified food have met with resistance in Europe, their hold on the US market is strong. They're also expanding operations in less-regulated countries in Africa, Asia and the former Soviet bloc. The US has launched a legal suit to attempt to force the European market open to genetically modified food. What does the future hold? This brilliantly readable book tells us all we need to know.

Maris Boyd Gillette's groundbreaking study tells the story of Jingdezhen, China's porcelain capital, from its origins in 1004 in Song dynasty China to the present day. Gillette explores how Jingdezhen has been affected by state involvement in porcelain production, particularly during the long 20th century. She considers how the Chinese government has consumed, invested in, taxed and managed the local ceramics industry, and the effects of this state intervention on ceramists' lives, their local environment and the nature of the goods they produce. Gillette traces how Jingdezhen experienced the transition from imperial rule to state ownership under communism, the changing fortunes of the ceramics industry in the early 21st century, the decay and decline that accompanied privatisation, and a revival brought about by an entrepreneurial culture focusing on the manufacture of highly-prized 'art porcelain'.

The first book to details the history and social implications of the little blue pill Since its introduction in 1998, Viagra has launched a new kind of sexual revolution. Quickly becoming one of the most sought after drugs in history, the little blue pill created a sea change within the pharmaceutical industry-from how drugs could be marketed to the types of drugs put into development-as well as the culture at large. Impotency is no longer an embarrassing male secret; now it is called "erectile dysfunction," and is simply something to "ask your doctor" about. And over 16 million men have. The Rise of Viagra is the first book to detail the history and the vast social implications of the Viagra phenomenon. Meika Loe argues that Viagra has changed what qualifies as normal sex in America. In the quick-fix, pill-for-everything culture that Viagra helped to create, erections can now be had by popping a pill, making sex on demand, regardless of age or infirmity, and, potentially, for the rest of one's life. Drawing on interviews with men who take the drug, their wives, doctors and pharmacists as well as scientists and researchers in the field, this fascinating account provides an intimate history of the drug's effect on America. Loe also examines the quest for the female Viagra, the impact of the drug around the world, the introduction of new erection drugs, like Levitra and Cialis, and the rapid growth of the multi-billion dollar pharmaceutical industry. This wide-ranging book explains how this medical breakthrough and cultural phenomenon have forever changed the meaning of sex in America.

The Future of Work in Asia and Beyond presents the findings and associated implications arising from a collaborative research study conducted on the potential impact of the Fourth Industrial Revolution (4IR - or Industry 4.0) on the labour markets, occupations and associated future workforce competencies and skills across ten countries. The 4IR concerns the digital transformation in society and business - an interface between technologies in the physical, digital and biological disciplines. The book explores many related issues: the nature of the 4IR, as well as demographic, generational and socio-cultural issues, economic and political perspectives, public and private sector similarities and differences, business strategy and managerial implications, human resource management/planning strategies, policies and practices, industry innovations, 'best practice' cases and comparative country studies. Chapters are based on a framework which combines labour market and multiple stakeholder theories. Issues are explored through the perceptions of organisational managers based in Australia, China, India, Indonesia, Malaysia, Mauritius, Nepal, Singapore, Taiwan and Thailand to provide an analysis of organisational, industry and government preparedness for the 4IR. This book is recommended reading for anyone wanting to gain an understanding of the 4IR and a range of related challenges and issues, as well as suggested strategies for governments, education and industry that are necessary to address them.

The pharmaceutical industry is under increasing pressure to do more with less. Drug discovery, development, and clinical trial costs remain high and are subject to rampant inflation. Ever greater regulatory compliance forces manufacturing costs to rise despite social demands for more affordable health care. Traditional methodologies are failing and the industry needs to find new and innovative approaches for everything it does. Six Sigma in the Pharmaceutical Industry: Understanding, Reducing, and Controlling Variation in Pharmaceuticals and Biologics is the first book to focus on the building blocks of understanding and reducing variation using the Six Sigma method as applied specifically to the pharmaceutical industry. It introduces the fundamentals of Six Sigma, examines control chart theory and practice, and explains the concept of variation management and reduction. Describing the approaches and techniques responsible for their own significant success, the authors provide more than just a set of tools, but the basis of a complete operating philosophy. Allowing other references to cover the structural elements of Six Sigma, this book focuses on core concepts and their implementation to improve the existing products and processes in the pharmaceutical industry. The first half of the book uses simple models and descriptions of practical experiments to lay out a conceptual framework for understanding variation, while the second half introduces control chart theory and practice. Using case studies and statistics, the book illustrates the concepts and explains their application to actual workplace improvements. Designed primarily for the pharmaceutical industry, Six Sigma in the Pharmaceutical Industry: Understanding, Reducing, and Controlling Variation in Pharmaceuticals and Biologics provides the fundamentals of variation management and reduction in sufficient detail to assist in transforming established methodologies into new and efficient techniques.

This book examines the political economy of attempts to restructure the Donbass, one of the Soviet Union's most important 'old economy' 'rustbelt' industrial regions. It shows how local interest groups have successfully frustrated the central government's and the World Bank's proposed market-oriented restructuring, and how a manufacturing-based regional economy is surviving, partially, with restructuring postponed.

Tavistock Press was established as a co-operative venture between the Tavistock Institute and Routledge & Kegan Paul (RKP) in the 1950s to produce a series of major contributions across the social sciences. This volume is part of a 2001 reissue of a selection of those important works which have since gone out of print, or are difficult to locate. Published by Routledge, 112 volumes in total are being brought together under the name The International Behavioural and Social Sciences Library: Classics from the Tavistock Press. Reproduced here in facsimile, this volume was originally published in 1951 and is available individually. The collection is also available in a number of themed mini-sets of between 5 and 13 volumes, or as a complete collection.

This book examines the experiences of the globalizing Korean automobile industry, with particular focus on the Hyundai Motor Company (HMC), one of the most prominent of the new Korean multinational corporations. It provides an overview of the changing nature of the global automobile industry, before considering in depth the globalization processes that the Korean automobile industry has undertaken.

Tracing the development of HMC as it recovered from the failure of its first venture overseas, in Canada, and tried again in India, the authors explore the similarities and differences between the practices which HMC implemented in India and Korea. They highlight the importance of production systems and employment relations as part of HMC's growth, and argue that if Korean companies such as HMC are to compete successfully as global automobile producers they will need to increase the proportion of overseas production, establish global supply chains and improve co-ordination between head office and subsidiaries.

Based upon extensive fieldwork in India and Korea, this book is a detailed account of the globalization of the Korean automobile industry and Hyundai Motor Company. Its findings will be of importance to all those who seek to understand the challenges faced by firms that attempt to become global players.