The global electronics industry is one of the most innovation-driven and technology-intensive sectors in the contemporary world economy. From semiconductors to end products, complex transnational production and value-generating activities have integrated diverse macro-regions and national economies worldwide into the "interconnected worlds" of global electronics. This book argues that the current era of interconnected worlds started in the early 1990s when electronics production moved from systems dominated by lead firms in the United States, Western Europe, and Japan towards increasingly globalized and cross-macro-regional electronics manufacturing centered in East Asia. By the 2010s, this co-evolution of production network complexity transformed global electronics, through which lead firms from South Korea, Taiwan, and China integrated East Asia into the interconnected worlds of electronics production across the globe. Drawing on literature on the electronics industry, new empirical material comprising custom datasets, and extensive personal interviews, this book examines through a "network" approach the co-evolution of globalized electronics production centered in East Asia across different national economies and sub-national regions. With comprehensive analysis up to 2021, Yeung analyzes the geographical configurations ("where"), organizational strategies ("how"), and causal drivers ("why") of global production networks, setting a definitive benchmark into the dynamic transformations in global electronics and other globalized industries. The book will serve as a crucial resource for academic and policy research, offering a conceptual, empirically driven grounding in the theory of these networks that has become highly influential across the social sciences.

Drug Delivery Trends examines a drift in the pharmaceutical field across the wide range of dosage forms, drug delivery systems (micro and nanoparticulate), at the regulatory front and on new types of therapies in the market. This volume additionally covers the challenges on drug delivery systems in terms of preclinical and current ways of determining quality and the options to solve the challenges associated with this. Most small-medium scale industries and academics struggle with initial regulatory challenges so a detailed discussion on regulatory trend covers the necessary basic understanding of regulatory procedures and provides the required guidance. The series Expectations and Realities of Multifunctional Drug Delivery Systems examines the fabrication, optimization, biological aspects, regulatory and clinical success of wide range of drug delivery carriers. This series reviews multifunctionality and applications of drug delivery systems, industrial trends, regulatory challenges and in vivo success stories. Throughout the volumes discussions on diverse aspects of drug delivery carriers, such as clinical, engineering, and regulatory, facilitate insight sharing across expertise area and form a link for collaborations between industry-academic scientists and clinical researchers. Expectations and Realities of Multifunctional Drug Delivery Systems connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stake holders. The wide scope of the book ensures it as a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about drug delivery systems.

Originally published in 1988, this book explores how new technologies, industrial innovation and the growth of high technology industry have affected regional employment and economic change in different European countries. It discusses the factors which make some areas better suited than others to the development of the new industries, emphasising how fuctional integration and dependence upon highly-qualified manpower tend to concentrate these industries in particular locations. Attempts to encourage innovation and the development of high technology industry in old industrial areas are discussed, with particular reference to the role of large firms, training programmes and government policies.

In the last quarter of the 20th century, politicians in Washington, as well as interest groups, regulatory policy makers, and drug industry leaders were forced to confront the hot-button issue of pharmaceutical regulation. The struggle always centered on product innovation, consumer protection, and choice in the free market. As the American economy stuttered in the late 1970s, the stakes were extremely high for the powerful drug industry and the American public. At the center of this drama was the Food and Drug Administration, which was censured from both the left and right of the political spectrum for being too strict and too lenient in the application of its regulatory powers. Lucas Richert explores the FDA, drugs, and politics in the context of the watershed Reagan era, a period when the rhetoric of limited government, reduced regulation, and enhanced cooperation between businesses and U.S. regulatory agencies was on the ascent. As he investigates the controversies surrounding Laetrile, Reye's Syndrome, Oraflex, patient package inserts, diet pills, and HIV/AIDS drugs, Richert argues that the practical application of conservative economic principles to the American drug industry was A Prescription for Scandal.

'An interesting and important account.' Daily Telegraph Have you ever stopped and wondered where your jeans came from? Who made them and where? Ever wondered where they end up after you donate them for recycling? Following a pair of jeans, Clothing Poverty takes the reader on a vivid around-the-world tour to reveal how clothes are manufactured and retailed, bringing to light how fast fashion and clothing recycling are interconnected. Andrew Brooks shows how recycled clothes are traded across continents, uncovers how retailers and international charities are embroiled in commodity chains which perpetuate poverty, and exposes the hidden trade networks which transect the globe. Stitching together rich narratives, from Mozambican markets, Nigerian smugglers and Chinese factories to London's vintage clothing scene, TOMS shoes and Vivienne Westwood's ethical fashion lines, Brooks uncovers the many hidden sides of fashion.

Technical standards play an important role in business as well as everyday life. They provide opportunities for market growth and competition. They enable interoperability. They make customers happier. They bring order out of chaos. Existing technical standards are being updated constantly, and new ones are being produced in increasingly greater numbers.

But do you know what it takes to create an "effective" standard?

The 'Ten Commandments for Effective Standards, ' written by computer chip industry veteran Karen Bartleson and illustrated by corporate cartoonist Rick Jamison, will not only provide you with ideas for creating better standards, it will also provide you with a newfound understanding of standards and their importance, respect for the standardization process, and ways you can leverage others' industry expertise to help you succeed in creating more effective technical standards.

Based upon twenty years of experience in the area of standards for electronic design automation and ideas drawn from other industry experts, the 'The Ten Commandments for Effective Standards' provides you with a list of procedural imperatives about what works and what doesn't work when developing effective technical standards.

This book will teach you how applying Bartleson's commandments to day-to-day standards activities can help make your resulting standards more effective and easier to adopt. From the Golden Rule of effective standards -- "cooperate on standards, compete on products" -- which points to the essence of standardization, to the tenth commandment -- "know that standards have technical and business aspects" -- which declares the importance of a standard's commercial implications, this book will provide you with a foundation for preparing for and performing in the technical standards arena.

Whether you are already involved in the process of creating technical standards or are interested in learning more about it, Bartleson's 'Ten Commandments for Effective Standards' is standard reading for anyone pursuing knowledge, excellence, and success in the field of technical standards.

Now in its ninth edition, Air Transportation: A Global Management Perspective by John Wensveen is a well-proven, accessible textbook that offers a comprehensive introduction to the theory and practice of air transport management. In addition to explaining the fundamentals, the book transports the reader to the leading edge of the discipline, using past and present trends to forecast future challenges and opportunities the industry may face, encouraging the reader to think deeply about the decisions a manager implements. The word "Global" has been added to the subtitle for this edition, reflecting an increased emphasis on worldwide operations including North America, Latin America/Caribbean, Europe, Asia-Pacific, the Middle East and Africa. The ninth edition focuses on the "Age of Acceleration", addressing trends related to emerging technologies, such as autonomy, artificial intelligence, augmented reality, virtual reality, 3-D printing, data analytics, block chain, cybersecurity, etc. New material includes extra information on airport management and operations, air carrier business models, aviation risk, safety and security, and how changing political landscapes impact the aviation industry. Enhanced content is supported by the addition of new chapters and online supplemental resources including PowerPoint presentations, chapter quizzes, exam questions and links to online resources. This wide-ranging textbook is appropriate for nearly all aviation programs that feature business and management. Its student-friendly structure and style make it highly suitable for modular courses and distance-learning programs, or for self-directed study and continuing personal professional development.

A solid, rigorous, yet comprehensible analysis of process capability indices, this work bridges the gap between theoretical statisticians and quality control practitioners, showing how an understanding of these indices can lead to process improvement.

One of the key issues that faces Cuban policymakers today, and will continue to face them, is what steps to take in order to ensure the future of the sugar industry. In 2002, nearly one-half of the country's cultivated land was occupied by the 156 fully functional sugar mills, more than a dozen plants and refineries, and the complex transportation infrastructure brought about by the commerce. The loss of preferential markets for Cuban sugar that arose from the demise of the international socialist community constitutes a crisis that the Cuban government has only begun to address, with a radical restructuring plan that would foresee the reduction of sugar land and the elimination of about 100,000 jobs, for increased economic emphasis on tourism. The radical premise of this volume is that there is a future in the twenty-first century for a reinvented Cuban sugar agroindustry, responsive to market signals, organized around smaller and more agile production units, producing raw sugar as well as high value-added outputs, and using some of the facilities to produce ethanol and generate electricity. The editors have asked over a dozen recognized world experts on Cuban agroindustry to analyze specific topics and make recommendations that would not only reinvent an industry for effective transition to a free-market environment but that has the potential to reinvigorate the Cuban economy, providing employment opportunities and generating wealth for generations of Cubans to come.

In 1945 Britain was the world's leading designer and builder of aircraft - a world-class achievement that was not mere rhetoric. And what aircraft they were. The sleek Comet, the first jet airliner. The awesome delta-winged Vulcan, an intercontinental bomber that could be thrown about the sky like a fighter. The Hawker Hunter, the most beautiful fighter-jet ever built and the Lightning, which could zoom ten miles above the clouds in a couple of minutes and whose pilots rated flying it as better than sex. How did Britain so lose the plot that today there is not a single aircraft manufacturer of any significance in the country? What became of the great industry of de Havilland or Handley Page? And what was it like to be alive in that marvellous post-war moment when innovative new British aircraft made their debut, and pilots were the rock stars of the age? James Hamilton-Paterson captures that season of glory in a compelling book that fuses his own memories of being a schoolboy plane spotter with a ruefully realistic history of British decline - its loss of self confidence and power. It is the story of great and charismatic machines and the men who flew them: heroes such as Bill Waterton, Neville Duke, John Derry and Bill Beaumont who took inconceivable risks, so that we could fly without a second thought.

The Story of Porsche is a compact and beautifully designed review of the iconic car manufacturer. From the alluring curves to the powerful engineering, Porsche has been synonymous with both luxury and race car manufacturing for more than 90 years. In The Story of Porsche, every component of the legendary brand's success is studied and celebrated, from turbulent beginnings to its ascent to the summit of car design and construction. Blending heritage with innovation and brand identity with creativity, Porsche has produced some of the most beloved models of sport and luxury car alike. From the timeless designs of the 911 and Carrera, to the dynamism of the 917, the fabled marque has instilled class and faultless engineering into each and every one of its creations. With 19 victories at Le Mans, Porsche has also proved itself to be as successful on the racetrack as it is on the streets; revered, respected and treasured in equal measure. These victories on both the podium and in the marketplace are rendered here in stunning detail through insightful text and exceptional photography. This is a story packed with blind corners and steep climbs, in a package that will sit perfectly on any Porsche fan's bookshelf.

Fibres to Smart Textiles: Advances in Manufacturing, Technologies, and Applications offers comprehensive coverage of the fundamentals and advances in the textile and clothing manufacturing sectors. It describes the basics of fibres, yarns, and fabrics and their end use in the latest developments and applications in the field and addresses environmental impacts from textile processes and how to minimize them. This book serves as a single comprehensive source discussing textile fibres, yarn formation, filament formation techniques, woven fabric formation, knitting technologies, nonwoven manufacturing technologies, braiding technologies, and dyeing, printing, and finishing processes. Testing of textile materials, environmental impacts of textile processes and use of CAD and CAM in designing textile products are also included. The book also discusses applications including textile composites and biocomposites, technical textiles, smart textiles, and nanotextiles. With chapters authored by textile experts, this practical book offers guidance to professionals in textile and clothing manufacturing and shows how to avoid potential pitfalls in product development.

This authoritative reference presents an up-to-date review of the testing methods, emerging technologies, and analytical systems and procedures used to prevent the microbial contamination of pharmaceutical processes, products, and environments. It identifies new tools for sample analysis and evaluation and the impact of these advancements on the continuous supply and manufacturing of pharmaceutical products. With more than 100 tables and 430 current references, the book contains a detailed analysis of microbial contamination recalls for nonsterile and sterile pharmaceutical products, demonstrating the distribution of microorganisms worldwide and the identification by geographical regions.

Containing 350 illustrations, tables, and equations and covering AAPS/FDA guidelines for the experimentation and analysis of in vivo and in vitro percutaneous absorption, this reference provides comprehensive coverage of the development, preparation, and application of topical and transdermal therapeutic systems. Recognized international experts discuss the bioequivalence of dermatological and transdermal dosage forms. They explore the biochemistry and treatment of skin diseases, the structure and function of the skin, adverse dermal responses to drug formulations, mechanisms of drug transport through barrier membranes, and methods for measuring and modulating percutaneous permeation.

The contributing authors of Understanding the Japanese Food and Agrimarket discuss broad forces that affect markets in Japan and specific situations faced in marketing grain, livestock, and seafood products; fruits; vegetables; and wood products. Many of the contributors speak and read Japanese and have lived in Japan for extensive periods; they are able to give deep insights into how and why the Japanese consumption and distribution system behaves as it does. They draw on their expertise to fully explore various Japanese food and fiber markets. As they demystify the Japanese market, they illustrate for readers several systematic approaches to mastering the Japanese food and fiber markets.Readers will discover that effective long-term marketing strategies in Japan must be based on sound analytical information. The contributors provide such needed material with chapters on items as diverse as wine, grain products, beef, and fruits and vegetables. Some of the specific topics covered include: changes in Japanese food consumption Japanese food distribution system demand for beef products in Japan demand for vegetables and vegetable seeds Japanese wine market demand for bakery products new food products for the Japanese market developing trade relations in wood productsExecutives of commodity associations or firms exporting foods to Japan will find the general sections most interesting as well as chapters specific to their products. Teachers and students exploring exporting to the Japanese market will be intrigued by the various dimensions of the "multifaceted" nature and opportunities of the Japanese market.

This book addresses the question of how competition takes place in international manufacturing industries. It examines patterns of rivalry among firms from different countries across national boundaries and their influences on international trade and investment. By using various data on Japanese firms in manufacturing industries from the late 1950s through the early 2000s, the first part of this book presents a series of empirical analyses that examines effects of market structure on export pricing, linkages of domestic and foreign market structures on trade performance, and patterns of oligopolistic interactions among firms from different countries in exporting. The second part of this book deals with the impact of strategic interactions on foreign direct investment. In particular, the book examines 'bunching' in foreign direct investment, strategic interactions in intra-industry cross-market foreign direct investment, and their effects on entry patterns and post-entry performance.

Interactions between drug particulates are crucial in determining drug dispersion and deaggregation, and ultimately delivery efficiency. This book combines principles and factors in pharmaceutical powder technology, critically reviews some of the studies carried out in dry powder formulation development, and proposes possible strategies for improving their efficiency. The majority of these principles are applicable to other pharmaceutical solid dosage forms (e.g. tablets and capsules).

Knowing how to deal with the regulatory issues, understanding the impacts of cleanliness, and recognizing the affect that poor facility layout will have on GMP spaces are only some of the issues an experienced Project Manager must focus on. Completely revised and updated, Sterile Product Facility Design and Project Management, Second Edition provides comprehensive guidance on how to develop and execute biotech and other sterile drug facilities based on current industry best practices. Each chapter highlights a specific issue centered on managing biotech facilities projects in a GMP environment. The author uses real-world examples of common industry practice to lead you through the idiosyncrasies of a biotech project in an effort to answer some of the more common, and often perplexing, questions that can stand in the way of success. You get a mini seminar on each topic covered. Breaking the project life-cycle into four phases, the text takes you through each phase from the Project Manager's viewpoint. Unlike other books that cover design, technology, and validation in general terms, this book addresses the industry specific issues that make biotech facilities so costly and difficult to deliver. It puts the pieces of the puzzle together in a manner that increases your opportunity for success.

Originally published in 1983, Interpretations of Calamity provides a provocative critique of the 'dominant view' of research into natural hazards. Throughout the world, there are now many people professionally engaged in the mitigation and control of risks & hazards, and the impact of continuing economic development will ensure that they are fully employed. There is a wealth of perspectives in the book, including weather and wheat yields in the Soviet Union and Canada, an historical view of underdevelopment and hazards in Ireland and the impact of a response to drought in southern Africa, the Sahel and the Great Plains of the USA. The book reflects the major themes of hazards in the context of economic development and social change. Most of the case studies are from the rural and agriculture scene. This book provides a unique view of the vital importance of food production and of the considerable, and sometimes calamitous, impact that frost, flood, storm and drought have on the wellbeing of millions of people and on the stability of the international economic system.

In a finished nutraceutical product, flavors play an integral role. Flavor Development for Functional Foods and Nutraceuticals is about the crucial role added flavors play in any nutraceutical product. It describes the various extraction techniques that are being adopted for manufacturing flavors from natural raw materials. Yield and retention of aromatic components during several extraction methods and flavor encapsulation techniques for thermal degradable food components are discussed. Advanced methods of flavor extraction techniques like supercritical C02 extraction are emphasized. The safety and quality aspects of flavor incorporation in food processing industries are reviewed with respect to international regulations. The importance of flavor in the nutraceuticals industry is also discussed. In addition, the book stresses the functional value and organoleptic acceptability towards product optimization/formulation. Features: Explains how flavors play an integral role in a finished nutraceutical product Describes the various extraction techniques that are being adopted for manufacturing flavors from natural raw materials Covers flavor encapsulation techniques for thermal degradable food components Provides an introduction to the history of how some natural flavor ingredients, botanicals, and extracts were used in ancient times in Ayurveda and herbal medicine This is an ideal reference book for the flavor chemists, food scientists, nutraceutical formulators, and students and academicians who are working in the area of nutraceutical, supplement, and functional food development and provides very useful information to help them select appropriate flavors for their products. Also available in the Nutraceuticals: Basic Research/Clinical Applications Series: Flavors for Nutraceuticals and Functional Foods, edited by M. Selvamuthukumaran and Yashwant Pathak (ISBN: 978-1-1380-6417-1) Antioxidant Nutraceuticals: Preventive and Healthcare Applications, edited by Chuanhai Cao, Sarvadaman Pathak, Kiran Patil (ISBN 978-1-4987-3703-6) Food By-product Based Functional Food Powders, edited by OEzlem Tokusoglu (ISBN 978-1-4822-2437-5)

In 1926, the Carriage Builders' National Association met for the last time, signaling the automobile's final triumph over the horse-drawn carriage. Only a decade earlier, carriages and wagons were still a common sight on every Main Street in America. In the previous century, carriage-building had been one of the largest and most dynamic industries in the country. In this sweeping study of a forgotten trade, Thomas A. Kinney extends our understanding of nineteenth-century American industrialization far beyond the steel mill and railroad. The legendary Studebaker Brothers Manufacturing Company in 1880 produced a hundred wagons a day--one every six minutes. Across the country, smaller factories fashioned vast quantities of buggies, farm wagons, and luxury carriages. Today, if we think of carriage and wagon at all, we assume it merely foreshadowed the automobile industry. Yet., the carriage industry epitomized a batch-work approach to production that flourished for decades. Contradicting the model of industrial development in which hand tools, small firms, and individual craftsmanship simply gave way to mechanized factories, the carriage industry successfully employed small-scale business and manufacturing practices throughout its history.

"The Carriage Trade" traces the rise and fall of this heterogeneous industry, from the pre-industrial shop system to the coming of the automobile, using as case studies Studebaker, the New York-based luxury carriage-maker Brewsters, and dozens of smallerfirms from around the country. Kinney also explores the experiences of the carriage and wagon worker over the life of the industry. Deeply researched and strikingly original, this study contributes a vivid chapter to the story of America's industrial revolution.

With over twenty different official regulatory statements worldwide on Good Manufacturing Practice (GMP) for pharmaceutical, drug, or medicinal products, two stand out as being the most influential and most frequently referenced. Bridging the gap between U.S. regulations and European Good Manufacturing Practice guidelines, Good Pharmaceutical Manufacturing Practice: Rationale and Compliance gleans the most important substance from the U.S. Current Good Manufacturing Practice, parts 210 and 211 (US cGMPs, 2002) and the European Guide to Good Manufacturing Practice for Medicinal Products for Human and Veterinary Use (EU GMP guide, 2002). The author uses his 40+ years of experience in technical management, production, quality assurance, and distribution within the pharmaceutical industry, offering a hands-on guide to better understand and implement optimal pharmaceutical practices. This book also compares the principle requirements of GMP, and explores the reasoning behind these requirements and ways to comply with them. Relevant topics include personnel, documentation, premises and equipment, production, quality control, self-inspection, recalls, and more. This is an essential guidebook for those who wish to expand their pharmaceutical business in any international capacity.

Bringing together the concepts of design control and reliability engineering, this book is a must for medical device manufacturers. It helps them meet the challenge of designing and developing products that meet or exceed customer expectations and also meet regulatory requirements. Part One covers motivation for design control and validation, design control requirements, process validation and design transfer, quality system for design control, and measuring design control program effectiveness. Part Two discusses risk analysis and FMEA, designing-in reliability, reliability and design verification, and reliability and design validation.

Pharmaceutical Production Facilities: Design and Applications considers the concepts and constraints that have to be considered in the design of small, medium and large scale production plants. The layout, along with the flow of materials and personnel through facilities are considered with reference to ensuring compliance with current good manufacturing practice. The book explains how clean rooms have developed, and how recent regulations affect their design. The latest concepts for reducing contamination levels from the operator and the product are discussed. It assess current changes in standards and quality control and makes suggestions for the "ideal production environment" to enable standards to be validated to current standards.

Written by an expert for those who must design validatable cleaning processes and then validate those processes, this book discusses interdependent topics from various technical areas and disciplines. It shows how each piece of the cleaning process fits into the validation program, making it more defensible in both internal quality audits and external regulatory audits. Designed for use in the overall validation program, the book demonstrates how to build a comprehensive program, and includes discussion and examples of cleaning systems, regulatory requirements, and special topics and issues. It provides an FDA cleaning validation guidance document and a comprehensive glossary.