The pharmaceutical industry has encountered major shifts in recent years, both within the industry, and in its external environment. The cost of healthcare rising due to an ageing population, the intensification of regulatory requirements and mergers within the industry have led to an increased need for restructuring, cost reduction and culture change projects. Project management is the key to addressing these needs, and also to effective drug development. Given the costs of development and the critical issue of 'time to market', project management techniques - appropriately used - are a key factor in bringing a drug to market. In this book, Laura Brown and Tony Grundy's pharmaceutical expertise and experience offers the reader a guide to the most relevant project management tools and techniques and how to rigorously apply them in the pharmaceutical industry. The authors cover the technical, strategic and human aspects of project management, including contingency planning, simulation techniques and different project options. Complete with decision-tree diagrams, checklists, exercises and a full glossary, Project Management for the Pharmaceutical Industry provides clinical research, drug development and quality assurance managers or directors with a one-stop reference for successfully managing pharmaceutical projects. The text has been revised for this edition and now includes some additional material on risk management.

This book explores connections between activist debates about food sovereignty and academic debates about alternative food networks. The ethnographic case studies demonstrate how divergent histories and geographies of people-in-place open up or close off possibilities for alternative/sovereign food spaces, illustrating the globally uneven and varied development of industrial capitalist food networks and of everyday forms of subversion and accommodation. How, for example, do relations between alternative food networks and mainstream industrial capitalist food networks differ in places with contrasting histories of land appropriation, trade, governance and consumer identities to those in Europe and non-indigenous spaces of New Zealand or the United States? How do indigenous populations negotiate between maintaining a sense of moral connectedness to their agri- and acqua-cultural landscapes and subverting, or indeed appropriating, industrial capitalist approaches to food? By delving into the histories, geographies and everyday worlds of (post)colonial peoples, the book shows how colonial power relations of the past and present create more opportunities for some alternative producer-consumer and state-market-civil society relations than others.

The intellectual adventure of developing the atomic bomb at Los Alamos has been well documented, but the fact is that 90% of the Manhattan Project expenditures went to produce the exotic nuclear explosive materials required. That is the story told here, a story of the brilliant harnessing of American industry to build a coordinated network of huge production plants using technology that was being developed even as the plants themselves were rising. It is the story of multiple, complex production methods being pursued simultaneously without knowing any of them would ultimately work, a story of daring gambles and their ultimate redemption. It is the story of the frantic building of subsequent, larger plants that were worked to the limits of their safe operation during the Cold War arms race. This is a story told by the author in historical narrative and new high-resolution photographs of fast-disappearing relics.

The Cadillac story is more than the story of a car company. It is, in many ways, the story of the American automobile industry itself-- which, as much as any industry, drove America's growth in the twentieth century and defined who we are as a people: mobile and prosperous. Cadillac, again and again, played a critical role in that story, for both good and ill.
In the depths of the Great Depression, the brand redefined itself and the luxury market. After World War II, it epitomized expansive prosperity. Then, in the 1980s, it epitomized the industrial crisis that had suddenly overtaken America. Today, Cadillac's struggle to survive in a furiously competitive--and suddenly international--automobile industry mirrors the challenges facing American industry as a whole. Its success in meeting those challenges will have much to say about the future of American industry and of General Motors.

'This riveting behind-the-scenes story of the clothes on our backs is a must-read for clotheshorses everywhere' Harper's Bazaar 'Extraordinary . . . fascinating . . . a wonderful way into history, quite often through the voices of people who don't have a say in history' Cerys Matthews Linen, Cotton, Silk, Synthetics, Wool: through the stories of these five fabrics, Sofi Thanhauser illuminates the world we inhabit in a startling new way, travelling from China to Cumbria to reveal the craft, labour and industry that create the clothes we wear. From the women who transformed stalks of flax into linen to clothe their families in nineteenth century New England to those who earn their dowries in the cotton-spinning factories of South India today, this book traces the origins of garment-making through time and around the world. Exploring the social, economic and environmental impact of our most personal possessions, Worn looks beyond care labels to show how clothes reveal the truth about what we really care about. 'A must-read . . . combines remarkable research with heartfelt care' Clare Hunter

What we eat - as well as how it is produced, processed, moved, sold, and used by our bodies seems to matter like never before. Global Foodscapes takes on this topicality and asks readers to think about how we are all involved in the making of an odd and, in many ways, troubling and contested food economy. It explores how food is conceived, traded, grown, reared, processed, sold, and consumed; investigates what goes wrong along the way; and assesses what diverse people around the world are doing to fix these faults. The text uses a carefully-crafted framework that explores the interaction of five forms of oppression and five means of resistance as they are worked out over five stages in the food economy. It draws on case studies from around the world that illuminate key issues about food in today's world; examines how oppression affects diverse people caught up in the food economy; and highlights how individuals, groups, and institutions such as governments, but also firms, are trying to improve how we interact with the food system. Global Foodscapes is a highly accessible and useful text for undergraduate students interested in the global food economy. The global range of case studies, examples, and reference points, as well as its original framework allows the text to speak to diverse audiences and generate debate about whether anything - and if so, what - needs to be done about the food system we depend upon so heavily. Additional materials such as suggested readings and discussion points help students consider the issues at hand and conduct initial and more detailed research on today's food economy.

What we eat - as well as how it is produced, processed, moved, sold, and used by our bodies seems to matter like never before. Global Foodscapes takes on this topicality and asks readers to think about how we are all involved in the making of an odd and, in many ways, troubling and contested food economy. It explores how food is conceived, traded, grown, reared, processed, sold, and consumed; investigates what goes wrong along the way; and assesses what diverse people around the world are doing to fix these faults. The text uses a carefully-crafted framework that explores the interaction of five forms of oppression and five means of resistance as they are worked out over five stages in the food economy. It draws on case studies from around the world that illuminate key issues about food in today's world; examines how oppression affects diverse people caught up in the food economy; and highlights how individuals, groups, and institutions such as governments, but also firms, are trying to improve how we interact with the food system. Global Foodscapes is a highly accessible and useful text for undergraduate students interested in the global food economy. The global range of case studies, examples, and reference points, as well as its original framework allows the text to speak to diverse audiences and generate debate about whether anything - and if so, what - needs to be done about the food system we depend upon so heavily. Additional materials such as suggested readings and discussion points help students consider the issues at hand and conduct initial and more detailed research on today's food economy.

Basic Manufacturing has already established itself as a core text for manufacturing courses in Further Education. The new edition has been revised to be fully in line with the new Vocational GCSE in Manufacturing from Edexcel, covering the three compulsory units of this scheme, and will continue to act as a core text for Intermediate GNVQ. Coverage of the two schemes is combined throughout the text, yet each chapter clearly illustrates which sections map to which units within the two scheme specifications. The author's approach is student-centred with self-check questions and activities provided throughout. As a result, the book is well suited to independent study. It is also clearly written to appeal to students of all abilities. Review questions are provided at the end of each chapter to consolidate learning and give practice for external assessments. The third edition contains a brand new chapter to cater for the examinable part of the GCSE syllabus (Unit 3), which includes case studies in the six sectors covered in the scheme: food and drink/biological and chemical; printing and publishing/paper and board; textiles and clothing; engineering fabrication; mechanical/automotive engineering; electrical and electronic engineering/computer/process control/telecommunications. The book is an excellent, readable introduction to the technical and business aspects of the manufacturing industry that will be invaluable for students on a wide range of courses, including City and Guilds certificates. It also provides a good grounding for students embarking on higher-level programmes within Manufacturing. Roger Timings is one of the UK's leading authors of textbooks on manufacturing and engineering.

This book provides insight into the potential for the market to protect and improve labour standards and working conditions in global apparel supply chains. It examines the possibilities and limitations of market approaches to securing social compliance in global manufacturing industries. It does so by tracing the historic origins of social labelling both in trade union and consumer constituencies, considering industry and consumer perspectives on the benefits and drawbacks of social labelling, comparing efforts to develop and implement labelling initiatives in various countries, and locating social labelling within contemporary debates and controversies about the implications of globalization for workers worldwide. Scholars and students of globalisation, development, corporate social responsibility, human geography, labour and industrial relations, business ethics, consumer behaviour and fashion will find its contents of relevance. CSR practitioners in the clothing and other industries will also find this useful in developing policy with respect to supply chain assurance.

This book provides a systematic analysis of the law and practice of EU competition/antitrust law and trade regulation in the pharmaceutical sector. Authored by leading private practitioners, economists, scholars and high-profile competition enforcers, this work provides valuable insider knowledge on the application of competition law and policies to the pharmaceutical industry. Key features include: Extensive commentary on the legislation and the latest case law and administrative precedents in the pharmaceutical sector, at both EU and national level Coverage of various key developments including the recent pay-for-delay antitrust investigations, the perennial issues around parallel trade, and an examination of mergers among pharmaceutical companies and medical devices manufacturers In-depth analysis of topics commonly raised in the pharmaceutical sector including: pricing policies, IP life-cycle management, IP licensing and horizontal cooperation agreements Key economic and business perspectives to accompany legal analysis, providing the reader with a rounded view of the subject matter. This book will be a useful resource for lawyers and in-house counsel active in the pharmaceutical sector. The information and analysis provided will prepare readers to take on cases and drive the antitrust review of transactions and agreements within the industry. Researchers, economists and civil servants with an interest in competition law and trade regulation can also benefit from the practical insights provided therein.

Car Safety Wars is a gripping history of the hundred-year struggle to improve the safety of American automobiles and save lives on the highways. Described as the "equivalent of war" by the Supreme Court, the battle involved the automobile industry, unsung and long-forgotten safety heroes, at least six US Presidents, a reluctant Congress, new auto technologies, and, most of all, the mindset of the American public: would they demand and be willing to pay for safer cars? The "Car Safety Wars" were at first won by consumers and safety advocates. The major victory was the enactment in 1966 of a ground breaking federal safety law. The safety act was pushed through Congress over the bitter objections of car manufacturers by a major scandal involving General Motors, its private detectives, Ralph Nader, and a gutty cigar-chomping old politician. The act is a success story for government safety regulation. It has cut highway death and injury rates by over seventy percent in the years since its enactment, saving more than two million lives and billions of taxpayer dollars. But the car safety wars have never ended. GM has recently been charged with covering up deadly defects resulting in multiple ignition switch shut offs. Toyota has been fined for not reporting fatal unintended acceleration in many models. Honda and other companies have-for years-sold cars incorporating defective air bags. These current events, suggesting a failure of safety regulation, may serve to warn us that safety laws and agencies created with good intentions can be corrupted and strangled over time. This book suggests ways to avoid this result, but shows that safer cars and highways are a hard road to travel. We are only part of the way home.

What does excellent manufacturing management mean? Management texts to date have emphasized that it is, above methods such as SPC or TQM, a matter of "intangibles" and "culture". This book takes the myth out of management excellence; it can be learned and practiced: 1. Manage the four core processes, strategy formulation and deployment, product innovation, process development, and the supply chain, and 2. Pay attention to the seven dimensions of management quality, direction setting, integration, delegation, communication, participation, measurement, and employee development. Thus, we argue that an excellent manufacturing manager can move to a plant in a different industry and become, after an appropriate time to learn its specific technologies, an excellent manufacturing manager there as well. This book explains management quality and demonstrates how it is implemented, with nine plant tours through world-class factories from different industries.

The semiconductor industry is a vital industry for military establishments worldwide, and the control of, or loss of control of, this key industry has enormous strategic implications. This book focuses on the globalization of the strategic semiconductor industry and the security ramifications of this process. It examines in particular the migration of the Taiwanese chip industry to China as part of the globalization of production processes, and the extent to which such a globalization process poses security challenges to the United States, China and Taiwan. Transcending disciplinary boundaries between international political economy, security studies, and the history of science and technology, this multidisciplinary work provides an in-depth understanding of the globalization-security nexus, and disentangles the key policy issues connected to a potential explosive flashpoint in world politics today.

The book highlights the biotechnological advancement in the area of food adulterants and outlines the current state of art technologies in the detection of food adulterants using omics and nanobiotechnology. The book provides insights to the most recent innovations, trends, concerns, and challenges in food adulterants. It identifies key research topics and practical applications of modern cutting-edge technologies employed for detection of food adulterants including: expansion of food adulterants market, potential toxicity of food adulterants and the prevention of food adulteration act, cutting-edge technology for food adulterants detection, and biosensing and nanobiosensing based detection of food adulterants. There is need for new resources in omics technologies for the application of new nanobiotechnology. Biotechnological Approaches in Food Adulterants provides an overview of the contributions of food safety and the most up-to-date advances in omics and nanobiotechnology approaches to a diverse audience from postgraduate students to researchers in biochemical engineering, biotechnology, food technologist, environmental technologists, and pharmaceutical professionals.

The Arado Flugzeugwerke devoted twenty years to making aviation history in Potsdam-Babelsberg. Within the pages of this book the reader will find the first comprehensive history of Arado, including many previously unpublished details about this little-known aviation company.

The History of Mitsubishi Corporation in London examines the culture clashes, the friendships and the changing businesses that Mitsubishi Corporation's London branch oversaw in the eighty-five years following its foundation. It examines the paradox of how Mitsubishi Corporation could operate internationally for nearly a century, and still remain resolutely Japanese. With the slowdown in Japanese economic growth however, this book asks whether the corporation needs to change its mission, as well as controversially questioning whether information technology is in fact a barrier to, rather than a driving force for, successful globalization. As a long-term employee of Mitsubishi both in Tokyo and London, Pernille Rudlin has a unique perspective on the world of Japanese corporate culture in Britain. No other corporate history has examined a Japanese subsidiary in such detail, including interviews with more than thirty employees past and present.

This new volume, Herbal Product Development: Formulation and Applications, addresses some of the challenges that hinder the path of successful natural products from laboratory to market. Highly skilled, experienced, and renowned scientists and researchers from around the globe offer up-to-date information that describes characteristics of herbs and herbal products, applications, evaluation techniques, and more. There is also a section dedicated to alternative medicinal strategies for the treatment and cure of diverse diseases. Also considered, of course, is the efficacy and safety of herbal products, which are of major concern. This valuable volume will be an important addition to the library of those involved in herbal product development and testing, including researchers, scientists, academicians, industry professionals, and students in this area.

Pharmaceutical product development is a multidisciplinary activity involving extensive efforts in systematic product development and optimization in compliance with regulatory authorities to ensure the quality, efficacy and safety of resulting products. Pharmaceutical Product Development equips the pharmaceutical formulation scientist with extensive and up-to-date knowledge of drug product development and covers all steps from the beginning of product conception to the final packaged form that enters the market and lifecycle management thereof. Applications of core scientific principles for product development are also thoroughly discussed in conjunction with the latest approaches involving design of experiment and quality by design with comprehensive illustrations based on practical case studies of several dosage forms. The book presents pharmaceutical product development information in an easy-to-read mode with simplified theories, case studies and guidelines for students, academicians and professionals in the pharmaceutical industry. It is an invaluable resource and hands-on guide covering managerial, regulatory and practical aspects of pharmaceutical product lifecycle management.

This is the first book to comprehensively record the authors authoritative knowledge and practical experience of IC manufacturing, including the tremendous developments of recent years. With its strong application orientation, this is a must-have book for professionals in semiconductor industries.

We live in a world saturated by chemicals--our food, our clothes, and even our bodies play host to hundreds of synthetic chemicals that did not exist before the nineteenth century. By the 1900s, a wave of bright coal tar dyes had begun to transform the western world. Originally intended for textiles, the new dyes soon permeated daily life in unexpected ways, and by the time the risks and uncertainties surrounding the synthesized chemicals began to surface, they were being used in everything from clothes and home furnishings to cookware and food. In A Rainbow Palate, Carolyn Cobbold explores how the widespread use of new chemical substances influenced perceptions and understanding of food, science, and technology, as well as trust in science and scientists. Because the new dyes were among the earliest contested chemical additives in food, the battles surrounding their use offer striking insights and parallels into today's international struggles surrounding chemical, food, and trade regulation.

This study is both a history of the American wine industry and an examination of its current structure and performance. In analysing market formation, Taplin focuses on a complex network of winery owners, winemakers and grape growers to see how relationships have shaped the evolution of this sector.

This detailed study is the first exploration of rural consumption of clothing in early nineteenth-century Britain. Drawing on evidence from a range of sources including newspapers, trade directories, court records, visual sources and surviving garments, Toplis investigates how the apparel of the mass of the British population was acquired.

Running counter to the general decline of technological industries in post-Victorian Britain, optical munitions provides an important, previously overlooked, study into the business of manufacturing.

First Published in 1998. Routledge is an imprint of Taylor & Francis, an informa company.

This book examines the nature and extent of competition in the pharmaceutical industry and analyses the interaction between market structure and selected elements of the marketing mix. It provides valuable insights into the level of promotional expenditure required to achieve a significant market share for new products; the use of price, new products and promotional strategies to protect market share; the effects of patent expiration on price levels and the use of pricing strategy to achieve market share. The book includes a brief comparative analysis of competition and marketing strategies in the US ethical pharmaceutical market.