This title was first published in 2001. The emergence and development of automobile production in Australia was a long, drawn out and costly business for car buyers and taxpayers. Wheels and Deals, is the story of some of the causes and effects of Australian Government policies on the local development of one of the most significant industries of the 20th century.

This study of Ferranti in its last six years of a long history provides a detailed exposition of the British and American businessmen who combined to terminate one of the UK's leading defence electronics firms. Involving action in the Middle East, South Africa and Pakistan, as well as the UK and USA, this highlights the precarious nature of international arms trading.

The contemporary opioid crisis is widely seen as new and unprecedented. Not so. It is merely the latest in a long series of drug crises stretching back over a century. In White Market Drugs, David Herzberg explores these crises and the drugs that fueled them, from Bayer's Heroin to Purdue's OxyContin and all the drugs in between: barbiturate "goof balls," amphetamine "thrill pills," the "love drug" Quaalude, and more. As Herzberg argues, the vast majority of American experiences with drugs and addiction have taken place within what he calls "white markets," where the prescription of addictive drugs is legal and medically approved. These markets are widely acknowledged but no one has explained how they became so central to the medical system in a nation famous for its "drug wars"--until now. Drawing from federal, state, industry, and medical archives alongside a wealth of published sources, Herzberg re-connects America's divided drug history, telling the whole story for the first time. He reveals that the driving question for policymakers has never been how to prohibit the use of addictive drugs, but how to ensure their availability in medical contexts, where profitability often outweighs public safety. Access to white markets was thus a double-edged sword for socially privileged consumers, even as communities of color faced exclusion and punitive drug prohibition. To counter this no-win setup, Herzberg advocates for a consumer protection approach that robustly regulates all drug markets while caring for people with addiction by ensuring them safe, reliable access to medication-assisted treatment. Accomplishing this requires rethinking a drug/medicine divide born a century ago that, unlike most policies of that racially segregated era, has somehow survived relatively unscathed into the twenty-first century. By showing how the twenty-first-century opioid crisis is only the most recent in a long history of similar crises of addiction to pharmaceuticals, Herzberg forces us to rethink our most basic ideas about drug policy and addiction itself--ideas that have been failing us catastrophically for over a century.

The subject of this book is applied Bayesian methods for chemistry, manufacturing, and control (CMC) studies in the biopharmaceutical industry. The book has multiple authors from industry and academia, each contributing a case study (chapter). The collection of case studies covers a broad array of CMC topics, including stability analysis, analytical method development, specification setting, process development and optimization, process control, experimental design, dissolution testing, and comparability studies. The analysis of each case study includes a presentation of code and reproducible output. This book is written with an academic level aimed at practicing nonclinical biostatisticians, most of whom have graduate degrees in statistics. * First book of its kind focusing strictly on CMC Bayesian case studies * Case studies with code and output * Representation from several companies across the industry as well as academia * Authors are leading and well-known Bayesian statisticians in the CMC field * Accompanying website with code for reproducibility * Reflective of real-life industry applications/problems

This book examines the impact of economic reforms in India on the pharmaceutical industry and access to medicines. It traces the changing production and trade pattern of the industry, research and development (R&D) preferences and strategies of Indian pharmaceutical firms, patent system alongside pricing policy measures and their shortcomings. It also analyses the public health financing system in India driven largely by out-of-pocket expenditure - about 60 per cent - and characterised by very high share of medicines in total health expenditure.

Policy analysis is a dynamic process of discovery rather than a passive exercise of memorizing facts and conclusions. This text provides opportunities to "practice the craft" of policy analysis by engaging the reader in realistic case studies and problem-solving scenarios that require the selection and use of applicable investigative techniques. US Agricultural and Food Policies will assist undergraduate students to learn how policy choices impact the overall performance of agricultural and food markets. It encourages students to systematically investigate scenarios with appropriate positive and normative tools. The book emphasizes the importance of employing critical thinking skills to address the complexities associated with the design and implementation of twenty-first-century agricultural and food policies. Students are asked to suspend their personal opinions and emotions, and instead apply research methods that require the careful consideration of both facts and values. The opportunities to build these investigative skills are abundant when we consider the diversity of modern agricultural and food policy concerns. Featuring case studies and critical thinking exercises throughout and supported by a Companion Website with slides, a test bank, glossary, and web/video links, this is the ideal textbook for any agricultural policy class.

This book presents decision support tools that can be used in the early design stage to analyze the feasibility of a product and its components for remanufacturing. It also covers how to design a product specifically for remanufacturing and offers supporting case studies. This is a comprehensive solutions guide for remanufacturing decision-making. The book illustrates an approach that can be used at the product End-of-Life (EOL) stage to generate optimized recovery plans for the returned products. Opportunities for Industry 4.0 to support remanufacturing along with case studies are included to showcase the decision-making tools. Remanufacturing and Remanufacturability Assessment for the Circular Economy: A Solutions Guide will be of interest to practitioners, business professionals, and researchers that work in the industrial and manufacturing sectors. Those involved with supply chain management and advanced technologies associated with Industry 4.0, sustainability, and integrated techniques of circular supply chains will also find this book very useful.

FDA's Drug Review Process and the Package Label provides guidance to pharmaceutical companies for writing FDA-submissions, such as the NDA, BLA, Clinical Study Reports, and Investigator's Brochures. The book provides guidance to medical writers for drafting FDA-submissions in a way more likely to persuade FDA reviewers to grant approval of the drug. In detail, the book reproduces data on efficacy and safety from one hundred different FDA-submissions (NDAs, BLAs). The book reproduces comments and complaints from FDA reviewers regarding data that are fragmentary, ambiguous, or that detract from the drug's approvability, and the book reveals how sponsors overcame FDA's concerns and how sponsors succeeded in persuading FDA to grant approval of the drug. The book uses the most reliable and comprehensive source of information available for writing FDA-submissions, namely text and data from NDAs and BLAs, as published on FDA's website. The source material for writing this book included about 80,000 pages from FDA's Medical Reviews, FDA's Clinical Pharmacology Reviews, and FDA's Pharmacology Reviews, from one hundred different NDAs or BLAs for one hundred different drugs. Each chapter focuses on a different section of the package label, e.g., the Dosage and Administration section or the Drug Interactions section, and demonstrates how the sponsor's data supported that section of the package label.

Materials and Technology for Sportswear and Performance Apparel takes a close look at the design and development of functional apparel designed for high-performance sportswear. Implementing materials, performance, technology, and design and marketing, the book examines this rapidly emerging textile market and outlines future directions and growing trends. The book begins by explaining how a comfort-driven focus has led the industry to embrace knitted fabric as a popular choice of constructional material. Using examples of leading brands, it outlines the basic terminology, structural details, and essential properties appropriate for performance apparel, especially for sportswear. This book describes the differences between woven and knitted structures, provides an understanding of fabric behavior and the characteristics of a functional garment, and outlines the importance of garment fit and consumer perception of garment comfort in its design and development. The authors present key research outcomes on the design and development of functional apparel designed for high-performance sportswear that explore smart materials, impact-resistant fabrics and pressure sensing. They consider the use of 3-D body scanning and its influence on pattern engineering for apparel product development; highlight the widely used fiber types for sportswear and the importance of fiber blends and their performance, and discuss the relevance of fabric structure and its interaction with the human body. The book also presents research on moisture management and temperature regulation and analyzes the performance and development of smart sportswear intended for monitoring health and performance for a range of end uses. A definitive guide detailing the future of functional clothing and sportswear, this book: Describes how to design and develop functional clothing for sportswear Reflects current research outcomes and industry requirements Clarifies with visual illustration, practical examples, and case studies an understanding of techniques and concepts Explores specifics of garment design such as fit, shape, function, fashion and design Focuses on a commitment to designing ethical and sustainable products

Consolidation activities such as mergers and acquisitions (M&As) have been one of the major strategies adopted by Indian firms to withstand global competition. M&As experienced a substantial increase in value and volume during the post-liberalization era, facilitated by the presence of foreign subsidiaries in the Indian market as well as competitive pressure on domestic firms. The increased foreign investment through M&As brought new dimensions to the fore such as the implications on technological performance, efficiency, and more importantly, competition in the Indian market. The Globalisation of Indian Business: Cross Border Mergers and Acquisitions in Indian Manufacturing provides an in-depth analysis of these issues, specifically aiming to understand whether the M&As strategies helped the firms to achieve their desired objectives in terms of improvement in technology, efficiency and market power in the context of the increase of M&As in India, using appropriate statistical and econometric techniques. The book is of additional importance in the context of the recently implemented Competition Act, replacing the thirty year old MRTP Act in India. The new Act aims to maintain competition and protect consumers' interests without harming that of the producers'. Based on the analysis, broadly, the study cautions the regulators to rethink the efficiency defence argument and become more vigilant on the creation of monopolies. On the other side, it suggests firms should reconsider their post-merger integration strategy since consolidation has not led to a sustainable increase in market share of the surviving firms.

Presents exclusive material on integration of 4D imaging and 4D printing Demonstrates the industrial applications of 4D imaging in 4D printing using multiple case studies Discusses use of open source 4D imaging tools for biomedical applications Includes in-house development of smart materials for 4D printing Reviews low cost, indigenous lab scale solutions for various veterinary applications

Consumer Science and Strategic Marketing: Case Studies in the Traditional Food Sector aims to close the gap between academic researchers and industry professionals through real world scenarios and field-based research. The book explores how consumer and sensory science has been implemented in the food industry for achieving the following strategic aims: rejuvenating product image, shaping new market places, achieving market differentiation and geographical diffusion, achieving customer loyalty, promoting traditional features of the product and defining product positioning in competitive environment. There is an emerging demand from food industry professionals and undergraduate and postgraduate students who attend business and agricultural studies courses who want to gain practical information through real cases and field-based research. This book aims to answer the following questions, amongst others: How research in the field of consumer science became relevant for marketing strategies?, Which tangible economic and financial outcomes have been obtained by the joint work of sensory scientists, researchers in marketing field and food business professionals?, and which communication methods and practices have been relevant to make the most of R&D in the food industry? Through case studies, successful examples and practices are provided, with newer inputs for further theoretical investigation given. Both current and future professionals in the food industry will gain insights that can be used in their business environment.

Provides the latest information on trends in this fast-growing market Focuses on the six marine taxa that offer the most exciting potential Gives practical guidance to anyone wishing to enter this sector

Lean is about building and improving stable and predictable systems and processes to deliver to customers high-quality products/services on time by engaging everyone in the organization. Combined with this, organizations need to create an environment of respect for people and continuous learning. It's all about people. People create the product or service, drive innovation, and create systems and processes, and with leadership buy-in and accountability to ensure sustainment with this philosophy, employees will be committed to the organization as they learn and grow personally and professionally. Lean is a term that describes a way of thinking about and managing companies as an enterprise. Becoming Lean requires the following: the continual pursuit to identify and eliminate waste; the establishment of efficient flow of both information and process; and an unwavering top-level commitment. The concept of continuous improvement applies to any process in any industry. Based on the contents of The Lean Practitioners Field Book, the purpose of this series is to show, in detail, how any process can be improved utilizing a combination of tasks and people tools and introduces the BASICS Lean (R) concept. The books are designed for all levels of Lean practitioners and introduces proven tools for analysis and implementation that go beyond the traditional point kaizen event. Each book can be used as a stand-alone volume or used in combination with other titles based on specific needs. Each book is chock-full of case studies and stories from the authors' own experiences in training organizations that have started or are continuing their Lean journey of continuous improvement. Contents include valuable lessons learned and each chapter concludes with questions pertaining to the focus of the chapter. Numerous photographs enrich and illustrate specific tools used in Lean methodology. Implementing Lean: Converting Waste to Profit explores implementation methods, line balancing methods, including baton zone or bumping, and implementing Lean in the office and machine shops. The goal of this book is to introduce the balance of the tools and how to proceed once the analysis is completed. There are many pieces to a Lean implementation and all of them are interconnected. This book walks through the relationships and how the data presented can be leveraged to prepare for the implementation. It also provides suggest solutions for improvements and making recommendations to management to secure their buy-in and approval.

Globally, nearly 70 billion animals are farmed annually for meat, milk and eggs. Two-thirds of these are farmed intensively. The views held by food companies on animal stewardship, and the management practices and processes that they adopt are, therefore, of critical importance in determining the welfare of these animals. Yet, despite the scale of the food industry's impact, farm animal welfare remains a relatively immature management issue. There is a lack of consensus around the specific responsibilities companies have for farm animal welfare, and around how companies should treat the animals in their or in their suppliers' care. This book, The Business of Farm Animal Welfare, provides an extensive, authoritative analysis of current corporate practice on farm animal welfare. It critically reviews and assesses the ethical and business case for action. Through a series of practitioner case-studies, it describes how companies have addressed farm animal welfare in their operations and supply chains. It analyses the key barriers to companies adopting higher standards of farm animal welfare, and offers a series of practical recommendations to companies, consumers and policy makers on the role that they might play in raising farm animal welfare standards across the food industry. As the first comprehensive account of business and farm animal welfare, this book is an essential resource for researchers, practitioners and general readers looking to understand and influence corporate practice on farm animal welfare.

Will the manufacturing industry in east-central Europe survive when the host countries join the European Union? This controversial book challenges the assumption, made by the European Commission, that industries in transitional economies should have little difficulty establishing and maintaining a competitive position after entry into the European Union. The analysis focuses on Hungary, Poland, the Czech Republic, Slovakia and the former east Germany. Issues discussed include: * changes in economic structures, the transformation of enterprises and financial restructuring * levels of competitiveness in the countries, the region and internationally * industrial policy in the region * levels and nature of investment * limits and sources of growth * integration into western Europe * dangers of over-hasty harmonization of macroeconomic conditions with the European Union The authors conclude that although the basic structures of a market economy are firmly established, the transition has not encouraged the development of more advanced industrial activities. They strongly suggest that there should be an active policy framework, based on international experience, specifically geared towards improving the international competitiveness of industry in east-central Europe.

Against the backdrop of growing anti-globalisation sentiments and increasing fragmentation of the production process across countries, this book addresses how the Indonesian economy should respond and how Indonesia should shape its trade and industrial policies in this new world trade environment. The book introduces evaluation not on tariffs but on new trade instruments such as non-tariff measures (SPS, TBT, export measures and beyond border measures), and looks at industrial policies from a broader perspective such as investment, accessing inputs, labour, services, research and innovation policies. "The Open Access version of this book, available at http://www.taylorfrancis.com/books/10.4324/9781315161976, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license."

This innovative and clearly written book examines the process of diversification as a strategy to promote innovation and growth within firms and to foster structural change in industry. Through a comparative case study of the aerospace industry, using cases of diversification at Dassault (France), Saab (Sweden) and Daewoo (South Korea), the author examines interactions between the firm and the state, and critically evaluates the role of national and sectoral institutions during the diversification process. He then uses these findings to propose a new, original model for diversification. Key features include: * an exploration of the ways in which the systems of innovation approach can be used to analyse strategies in firms * new insights into the concept of 'institutions' * an examination of the relationship between the behaviour of diversifying firms and institutions * path-breaking research on the South Korean aerospace industry. The combination of an up-to-date and thorough analysis of the general literature on diversification and its shortcomings, as well as three detailed case studies, will render this work invaluable to those interested in management studies and systems of innovation, and anyone working in the aircraft industry.

Cost Management in Plastics Processing: Strategies, Targets, Techniques, and Tools, Fourth Edition, makes readers think about current practices and how to go forward with effective cost management. This is a practical workbook that provides a structured approach to reducing costs in plastics processing for all the major plastics shaping processes (moulding, extrusion, forming) as well as elsewhere in the company (e.g., in factory services and non-manufacturing areas). Competition in all manufacturing sectors is increasing, and there is continuous pressure to drive costs down and to increase cost management. Good cost management improves profits and margins, improves management control and opens the door to becoming a world-class company. The approach throughout this book looks rigorously at where costs are incurred and proposes projects and targets for cost reduction. This book is designed to provide a well-structured map broken down into simple tasks and achievable goals. This book offers a structured approach to the techniques of cost management, from how costs are calculated by accountants, to the effective use of machines and labor, to the minimization of waste. It begins by looking at traditional methods of accounting and costing and whether these are helpful or accurate for project management. Practical examples of cost management in plastics processing are included, together with many useful flow charts and diagrams to illustrate the points under discussion.

This brand new textbook by one of the leading engineering authors covers basic sheet-metal fabrication and welding engineering principles and applications in one volume - an unrivalled comprehensive coverage that reflects current working and teaching practice. It is fully up-to-date with the latest technical information and best practice and also includes chapters on non-technical but equally essential subjects such as health and safety, personal development and communication of technical information.Roger Timings covers these areas of mechanical engineering and workshop practice in a highly practical and accessible style. Hundreds of illustrations demonstrate the practical application of the procedures described. The text includes worked examples for calculations and key points to aid revision. Each chapter starts with learning outcome summaries and ends with exercises which can be set as assignemnts.The coverage is based on the SEMTA National Occupational Standards which makes this book applicable to a wide range of courses and ensures it also acts as a vital ongoing reference source in day-to-day working practice. All students, trainees and apprentices at up to and including Level 3 will find this book essential reading, particularly those taking:Level 2 NVQs in Performing Engineering OperationsLevel 2 and 3 NVQs in Fabrication and Welding EngineeringLevel 2 NVQs in Mechanical Manufacturing EngineeringC&G 2800 Certificate and Level 3 Diplomas in Engineering and TechnologySEMTA Apprenticeships in Engineering

FDA Warning Letters About Food Products: How to Avoid or Respond to Citations uses examples of FDA warning letters about food products as training tools to discuss important quality and manufacturing issues encountered by food companies around the world as they bring food products into the US market. Focused specifically on FDA warning letters surrounding new dietary ingredients and dietary supplements, the book first introduces FDA warning letters in general. Each chapter then focuses on specific issues identified, including HAACP/quality systems, imports/exports, food contact issues, etc. This book helps the food industry train professional team members (across the spectrum of experience levels) to avoid common issues often cited in warning letters. It serves both as an authoritative reference on the common types of warning letters issued to food companies today, and as a guide to best practices for food manufacturers.

This monograph study of Japan's industrial development focuses on the role of entrepreneurship first in adopting more advanced Western technology and then in innovating new technologies and developing human resources according to its changing organizational needs. Unlike previous studies in English, it covers the whole of the period since the Meiji restoration, refusing to divide up the credit for Japanese growth between technological improvements and investments in human and physical capital. The book investigates the interaction between private entrepreneurial activities and public policy, through a general examination of economic and industrial development, a study of the evolution of management systems, and six industrial case studies.

As innovation moves from the lab to the market, a new research phase begins for the entrepreneur: the market research phase. Inspired by a new technology that can change the world, critical questions need to be addressed. Is there a market for my innovation? Who are my clients? What do they need? Is my innovation filling that gap in the market? Who are my competitors? How are they approaching the market? If these questions are unaswered, entrepreneurs meet potential investors or partners with only a basic understanding of their market. The objective of this book is to fill this gap. It is a practical manual that gives entrepreneurs real-world advice and tools to build a solid market model. The book provides tips, models and tools entrepreneurs can use to collect, interpret and present their market and integrate it into their business plan. What the entrepreneur learns in this book will help him throughout his journey. After going over the market research process, he will learn how to design and use a number of market research tools, and how to adapt them in a life science context. From building a web survey to preparing interviews to doing your own secondary research, this handbook will help him gain a comprehensive understanding of how to perform his own market research activities and how to analyze his data. Finally, a number of frameworks (such as the TAM-SAM-SOM as well as the KANO Model) are described so that he can efficiently share what he has learned, using models that simply yet effectively shares findings.

Surface engineering is considered an important aspect in the reduction of friction and wear. This reference text discusses a wide range of surface engineering technologies along with applications in a comprehensive manner. The book describes various methods in surface engineering technology with a thorough explanation of various aspects of each process that comes under this domain. Apart from an enhanced explanation of the process and its attributes, this book also gives insight into the types of materials, applications, and optimization of surface engineering techniques. It discusses important topics including surface engineering of the functionality of graded materials, materials characterization, processing of biomaterials, design, surface modification technologies and process control, smart manufacturing, artificial intelligence, and machine learning applications. The book: discusses computational and simulation analyses for better selection of process parameters covers optimizations of processes with state-of-the-art technologies discusses applications of surface engineering in medical, agricultural, architecture engineering, and allied sectors covers processing techniques of biomaterials in surface engineering The text is useful for senior undergraduate, graduate students, and academic researchers working in diverse areas such as industrial and production engineering, mechanical engineering, materials science, and manufacturing science. It covers a hybrid process for surface modification, modeling techniques, and issues in surface engineering.

Provides a detailed overview discussion on different classes of plant origin natural toxins in food. Explain how IR, NMR, and mass spectrometry are utilized in its characterization and identification. Describes applicability of HPLC, LC-MS, GC-MS, and HPTLC techniques for its detection and quantification Discusses progress of the field in utility of capillary electrophoresis, ELISA, and biosensors for quantitative application of the technique.