Emphasises an introduction and explanation of the practical methods used in reliability, and risk studies with a discussion of their uses and limitations Offers basic and advanced methods in reliability analysis that are commonly used in daily practice Provides methods that address unique topics such as dependent failure analysis, importance analysis, and analysis of repairable systems Presents a comprehensive overview of modern probabilistic life assessment methods such as Bayesian estimation, system reliability analysis, and human reliability Includes many ends of chapter problems, a tools website with computational codes, along with a solutions manual to support course adoptions

This book is an everything-included approach to understanding drones, creating an organization around using unmanned aircraft, and outlining the process of safety to protect that program. It is the first-of-a-kind safety-focused text book for unmanned aircraft operations, providing the reader with a required understanding of hazard identification, risk analysis, mitigation, and promotion. It enables the reader to speak the same language as any civil aviation authority, and gives them the toolset to create a safety risk management program for unmanned aircraft. The main items in this book break down into three categories. The first approach is understanding how the drone landscape has evolved over the last 40 years. From understanding the military components of UAS to the standards and regulations evolution, the reader garners a keen understanding of where we came from and why it matters for moving forward. The second approach is in understanding how safety risk management in aviation can be applied to drones, and how that fits into the regulatory and legislative environment internationally. Lastly, a brief synopsis of the community landscape for unmanned aircraft is outlined with interviews from important leaders and stakeholders in the marketplace. Drones fills a gap in resources within the unmanned aircraft world. It provides a robust understanding of drones, while giving the tools necessary to apply for a certificate of authorization, enabling more advanced flight operations for any company, and developing safety risk management tools for students and career professionals. It will be a mainstay in all safety program courses and will be a required tool for any and all individuals looking to operate safely and successfully in the United States.

Will the manufacturing industry in east-central Europe survive when the host countries join the European Union? This controversial book challenges the assumption, made by the European Commission, that industries in transitional economies should have little difficulty establishing and maintaining a competitive position after entry into the European Union. The analysis focuses on Hungary, Poland, the Czech Republic, Slovakia and the former east Germany. Issues discussed include: * changes in economic structures, the transformation of enterprises and financial restructuring * levels of competitiveness in the countries, the region and internationally * industrial policy in the region * levels and nature of investment * limits and sources of growth * integration into western Europe * dangers of over-hasty harmonization of macroeconomic conditions with the European Union The authors conclude that although the basic structures of a market economy are firmly established, the transition has not encouraged the development of more advanced industrial activities. They strongly suggest that there should be an active policy framework, based on international experience, specifically geared towards improving the international competitiveness of industry in east-central Europe.

Deep Stall applies a framework of strategic analysis to the Boeing Company. Boeing is the world's largest aerospace / defence company, with turnover in the region of US $60bn. The book examines the relative decline of Boeing in the civil aircraft market in relation to European manufacturer, Airbus. The aim of the book is to utilize the concept of strategic value to explain Boeing's decline. The authors define this concept as investment in people and technology to leverage future market success by developing innovative new products, arguing that Boeing has neglected strategic value in favour of shareholder value, defined in terms of short-term cash benefits. The rationale for the book exists both in the fact that the story in itself is interesting and also in the wider framework of analysis concerning the correct strategic approach for running a high technology business. The argument illustrates what can happen when quarterly returns become the predominant strategic rationale for a company. In the U.S. the business media (Economist, Forbes, Fortune, and Business Week etc) are now focusing on the question of Boeing's decline and the major implications for the U.S. national interest. Boeing is one of the jewels in the US technology crown, but today U.S. jobs and capability are being exported abroad, with most of its aircraft program work based in Asia. This is a hot topic in the US which explains why the business media are now so interested in this question. The book sits squarely in the centre of this debate. Deep Stall concludes with a brief analysis of the recent fight-back that has been evident in Boeing's fortunes and the successful campaign to sell the new 787. The authors probe the question of whether Airbus or Boeing is likely to dominate in the next ten or fifteen years.

Businesses that produce bioscience products--gene tests and therapies, pharmaceuticals, vaccines, and medical devices--are regularly confronted with ethical issues concerning these technologies. Conflicts exist between those who support advancements in bioscience and those who fear the consequences of unfettered scientific license. As the debate surrounding bioscience grows, it will be increasingly important for business managers to consider the larger consequences of their work.
This groundbreaking book follows industry research, development, and marketing of medical and bioscience products across a variety of fields, including biotechnology, pharmaceuticals, and bio-agriculture. Compelling and current case studies highlight the ethical decisions business managers frequently face. With the increasing visibility and public expectation placed on businesses in this sector, managers need to understand the ethical and social issues. This book addresses that need and provides a framework for incorporating ethical analysis in business decision making.

Textiles have been a highly valued and central part of the politics of human societies across culture divides and over millennia. The economy of textiles provides insight into the fabric of social relations, local and global politics, and diverse ideologies. Textiles are a material element of society that fosters the study of continuities and disjunctions in the economic and social realities of past and present societies. From stick-loom weaving to transnational factories, the production of cloth and its transformation into clothing and other woven goods offers a way to study the linkages between economics and politics. The volume is oriented around a number of themes: textile production, textiles as trade goods, textiles as symbols, textiles in tourism, and textiles in the transnational processes. Textile Economies appeals to a broad range of scholars interested in the intersection of material culture, political economy, and globalization, such as archaeologists, cultural anthropologists, economists, museum curators, and historians.

When a biological drug patent expires, alternative biosimilar products are developed. The development of biosimilar products is complicated and involves numerous considerations and steps. The assessment of biosimilarity and interchangeability is also complicated and difficult. Biosimilar Drug Product Development presents current issues for the development of biosimilars and gives detailed reviews of its various stages and contributing factors as well as relevant regulatory pathways and pre- and post-approval issues.

The global pharmaceutical industry is currently estimated to be worth $1 trillion. Contributors chart the rise of scientific marketing within the industry from 1920-1980. This is the first comprehensive study into pharmaceutical marketing, demonstrating that many new techniques were actually developed in Europe before being exported to America.

A comprehensive presentation of wicking models developed in academia and industry, Wicking in Porous Materials: Traditional and Modern Modeling Approaches contains some of the most important approaches and methods available, from the traditional Washburn-type models to the latest Lattice-Boltzmann approaches developed during the last few years. It provides a sound conceptual framework for learning the science behind different mathematical models while at the same time being aware of the practical issues of model validation as well as measurement of important properties and parameters associated with various models. Top experts in the field reveal the secrets of their wicking models. The chapters cover the following topics: Wetting and wettability Darcy's law for single- and multi-phase flows Traditional capillary models, such as the Washburn-equation based approaches Unsaturated-flow based methodologies (Richard's Equation) Sharp-front (plug-flow) type approaches using Darcy's law Pore network models for wicking after including various micro-scale fluid-flow phenomena Studying the effect of evaporation on wicking using pore network models Fractal-based methods Modeling methods based on mixture theory Lattice-Boltzmann method for modeling wicking in small scales Modeling wicking in swelling and non-rigid porous media This extensive look at the modeling of porous media compares various methods and treats traditional topics as well as modern technologies. It emphasizes experimental validation of modeling approaches as well as experimental determination of model parameters. Matching models to particular media, the book provides guidance on what models to use and how to use them.

Many argue that the sole viable future for the automobile industry - indeed for all industry - is the adoption of `lean production' as an organizational model. One Best Way? brings together the research of academic specialists in the automobile industry who have analysed the evolution of 15 major Asian, North American, and European companies in terms of their technological, organizational, commercial and social `trajectories'. They look closely at the evidence for `one best way' and argue that it is more useful to assess the distinctive challenges and `trajectories' that companies have pursued as they try to optimize their profit-making capacities. The book present detailed descriptions of the major producers around the world in three sections: Asia: Toyota, Nissan, Honda, Mitsubishi, Hyundai North America: General Motors, Ford, Chrysler Europe: Peugeot, Renault, Rover, Mercedes, Volvo, Lada The book will be essential reading and reference for academics, researchers, and analysts worldwide wanting to track the course of the automobile industry and assess the merits of `lean production'.

Plants require nutrients in order to grow, develop and complete their life cycle. Mineral fertilizers, and hence the fertilizer industry, constitute one of the most imp- tant keys to the world food supplies. There is growing concern about the safety and quality of food. Carbon, hydrogen and oxygen, which, together with nitrogen, form the structural matter in plants, are freely available from air and water. Nitrogen, phosphorus and potassium, on the other hand, may not be present in quantities or forms sufficient to support plant growth. In this case, the absence of these nut- ents constitutes a limiting factor. The supply of nutrients to the plants should be balanced in order to maximise the efficiency of the individual nutrients so that these meet the needs of the particular crop and soil type. For example, it should be noted that EU-wide regulations are not designed to govern the specific details of mineral fertilizer use. Although plants receive a natural supply of nitrogen, phosphorus and potassium from organic matter and soil minerals, this is not usually sufficient to satisfy the demands of crop plants. The supply of nutrients must therefore be supplemented with fertilizers, both to meet the requirements of crops during periods of plant growth and to replenish soil reserves after the crop has been harvested. Pesticides are important in modern farming and will remain indispensable for the foreseeable future.

The mood of the international grain market changed remarkably in the decade before this book was originally published in 1986. In the early 1970s, which were years of buoyancy and high prices, the concern was with feeding the starving millions and subsequently, in the United states, with the use of the grain embargo weapon to put pressure on the Soviet Union. In the mid-1980s, after a long period in which the recession kept prices down, the climate was much gloomier. The book considers the state of the major supplier countries and their particular problems. It charts the changes in the market and discusses major issues of international concern. It concludes by surveying prospects for the market.

In this timely title Professor Arti Rai brings together a wide range of articles that reveal the important role of intellectual property law in the formation and development of the dynamic and economically significant biotechnology industry. The collection encompasses theoretical articles that present principles of patent economics important to the industry, articles that discuss the patent law doctrines most relevant to biotechnology and empirical studies on the 'real world' effects of patents and secrecy. These are resonant issues in an ever-expanding field, and will establish this book as an essential reference point for lawyers, researchers and students.

Coffee Culture: Local experiences, Global Connections explores coffee as (1) a major commodity that shapes the lives of millions of people; (2) a product with a dramatic history; (3) a beverage with multiple meanings and uses (energizer, comfort food, addiction, flavouring, and confection); (4) an inspiration for humor and cultural critique; (5) a crop that can help protect biodiversity yet also threaten the environment; (6) a health risk and a health food; and (7) a focus of alternative trade efforts. This book presents coffee as a commodity that ties the world together, from the coffee producers and pickers who tend the plantations in tropical nations, to the middlemen and processors, to the consumers who drink coffee without ever having to think about how the drink reached their hands.

This book highlights the concepts of lean manufacturing that help to achieve the objectives of sustainability in a global competitive atmosphere. Lean can help to lower the manufacturing cost in the rising labour and material cost market. Lean is based on various fundamental concepts such as Kaizen, Kanban, Zidoka, 5S and Six Sigma, which aim at reducing process waste for efficiency and productivity that are discussed in this book. In addition, the technological changes such as introduction of Internet technologies and Industry 4.0 are taken care by the lean concepts, which are also addressed in this book.

Now there's a single easy-reading reference to help you plan, implement, and audit a HACCP (Hazard Analysis and Critical Control Point) program. HACCP User's Manual provides comprehensive information on new and existing HACCP systems, current U.S. Food and Drug Administration (FDA) and U.S. Department of Agriculture (USDA) regulations, and procedures for application of the system, as well as sanitation standard operating procedures (SSOPs). With more than 30 years' experience in the food industry, Don Corlett is eminently qualified to guide you step-by-step through the process of tailoring and operating a HACCP system to fit your operation. In HACCP User's Manual, you find expert tips for getting started, details on how to develop and implement a HACCP plan, and how to operate the HACCP system, including organization of record-keeping techniques.

Coffee: A Comprehensive Guide to the Bean, the Beverage, and the Industry offers a definitive guide to the many rich dimensions of the bean and the beverage around the world. Leading experts from business and academia consider coffee's history, global spread, cultivation, preparation, marketing, and the environmental and social issues surrounding it today. They discuss, for example, the impact of globalization; the many definitions of organic, direct trade, and fair trade; the health of female farmers; the relationships among shade, birds, and coffee; roasting as an art and a science; and where profits are made in the commodity chain. Drawing on interviews and the lives of people working in the business-from pickers and roasters to coffee bar owners and consumers-this book brings a compelling human side to the story. The authors avoid romanticizing or demonizing any group in the business. They consider basic but widely misunderstood issues such as who adds value to the bean, the constraints of peasant life, and the impact of climate change. Moving beyond simple answers, they represent various participants in the supply chain and a range of opinions about problems and suggested solutions in the industry. Coffee offers a multidimensional examination of a deceptively everyday but extremely complex commodity that remains at the center of many millions of lives. Tracing coffee's journey from field to cup, this handbook to one of the world's favorite beverages is an essential guide for professionals, coffee lovers, and students alike. Contributions by: Sarah Allen, Jonathan D. Baker, Peter S. Baker, Jonathan Wesley Bell, Clare Benfield, H. C. "Skip" Bittenbender, Connie Blumhardt, Willem Boot, Carlos H. J. Brando, August Burns, Luis Alberto Cuellar, Olga Cuellar, Kenneth Davids, Jim Fadden, Elijah K. Gichuru, Jeremy Haggar, Andrew Hetzel, George Howell, Juliana Jaramillo, Phyllis Johnson, Lawrence W. Jones, Alf Kramer, Ted Lingle, Stuart McCook, Michelle Craig McDonald, Sunalini Menon, Jonathan Morris, Joan Obra, Price Peterson, Rick Peyser, Sergii Reminny, Paul Rice, Robert Rice, Carlos Saenz, Vincenzo Sandalj, Jinap Selamat, Colin Smith, Shawn Steiman, Robert W. Thurston, Steven Topik, Tatsushi Ueshima, Camilla C. Valeur, Geoff Watts, and Britta Zeitemann

This book provides an overview of the brand construction process of manufacturing enterprises in Zhejiang province, China. There are now a number of industry-leading enterprises that are trying to build their own brands and manufacture products of higher quality in Zhejiang. The first chapter focuses on the place branding strategy employed by the Zhejiang Provincial Government in launching the "ZhejiangMade" brand to improve the perception of products made by Zhejiang manufacturing firms and promote them in the domestic and international markets. In the following nine chapters, the editors bring together case studies from nine leading enterprises in Zhejiang, including Baoxiniao, Shuanghuan, Feida, ROBAM, Xinhai, Yinlun, Weixing, Deli and Fotile, providing an analysis of their branding process.

Weaving as a subject is an integral part of any textile engineering/technology program, the others being fibre manufacturing, yarn manufacturing and textile chemical processing. This book amalgamates both the compartments (preparatory processes and the loom mechanism) of weaving technology and presents a holistic picture. The machine descriptions are presented from the viewpoint of principles and no attempt has been made to make them exhaustive by incorporating various models or variants. The mathematical relations among various parameters have been derived starting from the first principles and each chapter concludes with solved numerical examples.

This book explores connections between activist debates about food sovereignty and academic debates about alternative food networks. The ethnographic case studies demonstrate how divergent histories and geographies of people-in-place open up or close off possibilities for alternative/sovereign food spaces, illustrating the globally uneven and varied development of industrial capitalist food networks and of everyday forms of subversion and accommodation. How, for example, do relations between alternative food networks and mainstream industrial capitalist food networks differ in places with contrasting histories of land appropriation, trade, governance and consumer identities to those in Europe and non-indigenous spaces of New Zealand or the United States? How do indigenous populations negotiate between maintaining a sense of moral connectedness to their agri- and acqua-cultural landscapes and subverting, or indeed appropriating, industrial capitalist approaches to food? By delving into the histories, geographies and everyday worlds of (post)colonial peoples, the book shows how colonial power relations of the past and present create more opportunities for some alternative producer-consumer and state-market-civil society relations than others.

This book provides a fresh, multidisciplinary, and exciting look at the making and remaking of pharmaceutical patents at the GATT/WTO, by utilising a Coxian political economy of continuity and change in the global political economy (GPE). Marcellin focuses on the role of the transnational drug industry in the making of the patent provisions in the original TRIPS Agreement and consequently, the role of the African Group at the WTO in the remaking of those patent provisions.

A quality product or service is the successful and profitable outcome of organising resources, as judged by the final customer. Every business unit needs processes in order to do this effectively; and all processes must be documented so that achievements can be measured and future improvements planned and implemented. Pharmaceutical Process Design and Management takes a step-wise approach to process management. It presents the various elements comprising a process (man, machine, materials, method and environment); it looks at quality control and quality assurance, tools for quality improvements and ways of structuring a process into discrete, fully accountable elements; it proposes that for processes to run successfully, all operators must be the initial problem-solvers; finally, it illustrates how, with the right tools, every problem can be broken down into solvable elements. Learn how to deploy a science and risk-based approach to pharmaceutical manufacturing, by taking a fundamental approach to process design and management and, as a consequence, keep your customers satisfied and your profits healthy.

This book focuses on the lives, struggles, and contrasting perspectives of the 60,000 workers, military administrators, and technical staff employed in the largest, most strategic industry of the Nationalist government, the armaments industry based in the wartime capital, Chongqing. The author argues that China's arsenal workers participated in three interlocked conflicts between 1937 and 1953: a war of national liberation, a civil war, and a class war. The work adds to the scholarship on the Chinese revolution, which has previously focused primarily on rural China, showing how workers’ alienation from the military officers directing the arsenals eroded the legitimacy of the Nationalist regime and how the Communists mobilized working-class support in Chongqing. Moreover, in emphasizing the urban, working-class, and nationalist components of the 1949 revolution, the author demonstrates the multiple sources of workers’ identities and thus challenges previous studies that have exclusively stressed workers’ particularistic or regional identities.

This new edition provides an alternative overview of 18th-century British economy. Recent macroeconomic history has discounted many of the achievements of the Industrial Revolution, but this text dissects the characteristics and processes of industry in the 18th century. A male industrial revolution has been presented as the general experience, but new industries, notably in textiles and metal products, were primarily employers of women. This work gives these industries and their workforce due prominence. Technologies, work processes, labour forces and markets shifted in a variety of directions and forms to create a sector of dynamic new initiatives alongside stable and declining crafts. The key to the Industrial Revolution lies in the sources of technological creativity and the structures of industrial communities. The rise of the factory system was one result. This text reasserts the primacy of the industrial experience to Britain's economic history.

The pharmaceutical industry has encountered major shifts in recent years, both within the industry, and in its external environment. The cost of healthcare rising due to an ageing population, the intensification of regulatory requirements and mergers within the industry have led to an increased need for restructuring, cost reduction and culture change projects. Project management is the key to addressing these needs, and also to effective drug development. Given the costs of development and the critical issue of 'time to market', project management techniques - appropriately used - are a key factor in bringing a drug to market. In this book, Laura Brown and Tony Grundy's pharmaceutical expertise and experience offers the reader a guide to the most relevant project management tools and techniques and how to rigorously apply them in the pharmaceutical industry. The authors cover the technical, strategic and human aspects of project management, including contingency planning, simulation techniques and different project options. Complete with decision-tree diagrams, checklists, exercises and a full glossary, Project Management for the Pharmaceutical Industry provides clinical research, drug development and quality assurance managers or directors with a one-stop reference for successfully managing pharmaceutical projects. The text has been revised for this edition and now includes some additional material on risk management.