This book highlights key ideas and factors to coach and guide professionals involved in learning about Sterile Manufacturing and operational requirements. It covers regulations and guidelines instituted by the FDA, ISPE, EMA, MHRA, and ICH, emphasizing good manufacturing practice and inspection requirements in the manufacturing of medicinal products. Additionally, this book provides the fundamentals of aseptic techniques, quality by design, risk assessment, and management in support of sterile operations applications. It creates a link to the implementation of business practices in drug manufacturing and healthcare and forms a correlation between design strategies including a step-by-step process to ensure reliability, safety, and efficacy of healthcare products for human and animal use. The book also provides a connection between drug production and regulated applications by offering a review of the basic elements of sterile processing, and how to remain viable with solid strategic planning. The book is a concise reference for professionals and learners in the field of sterile operations that governs primarily, pharmaceutical and medical device space, but can also extend to food and cosmetics that require clean (aseptic) manufacturing applications. It also helps compounding pharmacists and GMP inspectors and auditors.

Like its predecessors, the new and updated edition of Advanced Nutrition: Macronutrients, Micronutrients, and Metabolism is an essential textbook for advanced undergraduate and first-year graduate students studying human nutrition. This book draws on inter-related sciences including biochemistry, genetics, and physiology to provide a full understanding of nutrition science. This third edition describes the chemistry, absorption, use and excretion of each of the essential nutrients. There is comprehensive coverage of nutrient-nutrient interactions and both macro and micronutrients. The book places strong emphasis on how nutrient-genetic interactions function with respect to disease development. The new edition includes some of the most recent descriptions of the roles nutrients play in the expression of genetic traits for a variety of degenerative diseases. It includes a new chapter explains the function of microorganisms in the maintenance and development of chronic degenerative disease. Features: Chapters address clinical conditions such as obesity, starvation, hyperlipemia, renal disease and organ function. Includes updated information on the body's microbiotica and the daily nutrient needs of humans across the life cycle. Material reveals the neurodegenerative response to dietary variables with respect to the regulation of food intake. Chapter summaries highlight key information and case studies challenge students to integrate what they have learned to solve clinical cases.

Drawing on anthropology, historical sociology and social-epidemiology, this multidisciplinary book investigates how pharmaceuticals are produced, distributed, prescribed, (and) consumed, and regulated in order to construct a comprehensive understanding of the issues that drive (medicine) pharmaceutical markets in the Global South today. Based on primary research conducted in Benin and Ghana, and additional data collected in Cambodia and the Ivory Coast, this volume uses artemisinin-based combination therapies (ACTs) against malaria as a central case study. It highlights the influence of the countries colonial and post-colonial history on their models for state regulation, production, and distribution, explores the determining role transnational actors as well as industries from the North but also and increasingly from the South play in influencing local pharmaceutical markets and looks at the behaviour of health care professionals and individuals. Stepping back, the authors then unpick the pharmaceuticalization process and the multiple regulations at stake by looking at the workings of, and linkages between, (biomedical health) pharmaceutical systems, (representatives of companies) industries, actors in private distribution, and consumer practices. Providing a thorough comparative analysis of the advantages and disadvantages of different pharmaceutical systems, it is an important contribution to the literature on pharmaceutalization and the governance of medication. It is of interest to students, researchers and policy-makers interested in medical anthropology, the sociology of health and illness, global health, healthcare management and pharmacy. The Open Access version of this book, available at http://www.taylorfrancis.com/books/9780429329517, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license.

In the year 2000, European Union governments announced a long-term strategic commitment to transform the European economy into the most competitive, dynamic, knowledge-based economy in the world. Technology is an integral part of the new economy and of the EU's strategy for economic development. This book deals with the development of infrastructure in the mobile communications, transport, space and radio sectors. It sets out to explain the conditions under which the EU, and in particular the European Commission, makes policy choices to support large-scale technology infrastructures, and why EU political intervention in seemingly similar infrastructure projects varies. Answering this question will provide insights into the political economy underpinning the ambitions to transform the European economy into the most competitive in the world. This study of EU political intervention in support of advanced technology will be a fascinating read for advanced students and academic researchers of international political economy, international affairs and political science. Competition for Technological Leadership will also appeal to journalists, policymakers and analysts with a special interest in EU high technology policy.

Aircraft Structures for Engineering Students, Seventh Edition, is the leading self-contained aircraft structures course text suitable for one or more semesters. It covers all fundamental subjects, including elasticity, structural analysis, airworthiness and aeroelasticity. Now in its seventh edition, the author has continued to expand the book's coverage of analysis and design of composite materials for use in aircraft and has added more real-world and design-based examples, along with new end-of-chapter problems of varying complexity.

Where presidents or members of affluent families were previously seen, it is increasingly the case that car manufacturers are owned by banks and investment funds which have taken control of the entire economic life of these firms. This has significant impact on the terms of employment and layoffs, wages and precarious work, growing inequalities in income strata, compensation levels for executives, and the implementation of short-termist strategies across business operations. This book explores this increasing financialisation - the predominance of the financial sector over the productive sector - in the automotive industry. In particular it is shown that the financial operations of these companies through leasing, insurance, loans and other financial instruments is now much more profitable than the manufacturing aspects of the business, which was originally the raison d'etre for these fi rms. The chapters demonstrate how there are great demands to increase the return to shareholders as a main concern, despite other metrics and/ or other stakeholders. The work studies the impact of financialisation at the world's five largest automakers which together represent almost 50% of car production, providing an exploratory analysis of profitability, shareholder composition, compensation to executives, workers' salaries, dividend payments to shareholders and employment. Encouraging debate on contemporary economy, this book marks a significant addition to the literature on financialisation, contemporary forms of capitalism, labour and economic sociology more broadly.

This book describes capacity building in strategic and non-strategic machine tool technology. It includes machine building in sectors such as machine tools, automobiles, home appliances, energy, and biomedical engineering, along with case studies. The book offers guidelines for capacity building in academia, covering how to promote enterprises of functional reverse engineering enterprises. It also discusses machine tool development, engineering design, prototyping of strategic, and non-strategies machine tools, as well as presenting communication strategies and IoT, along with case studies. Professionals from the CNC (Computer Numeric Control) machine tools industry, industrial and manufacturing engineers, and students and faculty in engineering disciplines will find interest in this book.

Many economically developing countries and nations without robust occupational hygiene (OH) educational programs endure a shortage of qualified occupational hygienists, resulting in higher rates of workplace injury, illness, and fatality. Damage to valuable infrastructure, environment, and public health also occurs without adequate support. Improving Global Worker Health and Safety Through Collaborative Capacity Building Initiatives outlines a broad variety of capacity building projects in OH. It also introduces detailed experiences of occupational hygienists working abroad and working on special global topics including a discussion of how global trade agreements influence the practice and policy within OH. It describes the special needs of informal workers who do not have a "typical" employer and special challenges of creating university curricular guidelines for OH, building competency, and increasing capacity. This book also informs experienced professionals in international OH-capacity building initiatives and directions. Features: Presents the global impact and importance of occupational hygienists Outlines knowledge and collaboration through networking Provides case studies on real world situations and problems This text will be useful for professionals and graduate students in the fields of occupational health and safety and public health.

In this book, Florence Wambugu and Daniel Kamanga of "Africa Harvest Biotech Foundation International" bring together expert African authorities to critique various biotechnology initiatives and project future developments in the field in Africa. For the first time, African voices from multidisciplinary fields as diverse as economics, agriculture, biotechnology, law, politics and academia, demand to be allowed to set the continent s biotech development agenda. This book argues that there is a great future for biotechnology in Africa which sidesteps western interests that do not match those of the local populace. In these diverse chapters, Africa s political and scientific leaders demand a greater say in how research and development funds are allocated and spent. They argue that Africa s political leaders must see both clear benefits and have elbow-room to drive the change required. This is the way that African governments can employ workable policies, suitable biosafety legislation and regulation and respond effectively to public-private partnerships. Wambugu and Kamanga show that biotechnology has the potential to improve food security and standard of living as well as mitigate the detrimental effects of climate change on the African continent."

In this book, author Sadao Nomura taps into his decades of experience leading and advising Toyota operations in a wide variety of operations to tell the story of radical improvement at Toyota Logistics & Forklift (TL&F). This book tells in great detail what the author did with TL&F, how they did it, and the dramatic results that ensued. TL&F has long been a global leader in its industry. TL&F is part of Toyota Industries Corporation, which was founded by Toyota Group founder Sakichi Toyoda almost 100 years ago. Sakichi Toyoda is legendary in the Lean community as the originator of the all-important "JIDOKA" pillar of TPS, which ensures 1) built-in quality and 2) respect for people through ensuring that technology works for people rather than the other way around. Although TL&F seemed to be performing well, insiders knew that, as the founding company of the Toyota group, it needed to do better, especially in the quality performance of its global subsidiary operations. But improvement would not be easy in a company that already prided itself in its history as an exemplar in providing highest quality products and services. In 2006, TL&F requested assistance from Sadao Nomura. The initial request was for Mr. Nomura to support quality improvement in three global operations that had become part of TL&F through acquisition: US, Sweden, and France. Improvement was expected at these affiliates, but the dramatic nature of the improvement was not. Further, the improvement activities were so powerful that they were also instituted at the parent operations in Japan. Over a period of almost ten years, the company with the name most associated with product quality experienced quality improvement unparalleled in its history. "Dantotsu" means "extreme," "radical," or "unparalleled."

This book analyzes the choices and constraints of management within the Bangladesh garment industry and how management negotiates these challenges to ensure the global garment supply chain is sustainable. Exploring the international South Asian garment industry and using middle management and the owners of Bangladeshi factories as a case study, the book assesses the limits and costs of globalization for Bangladesh, and outlines the challenges of the fast-fashion business model for the global market. It focusses on the changing dynamics of the entrepreneur class, how they manage factories and their experiences with Accord-Alliance, and the challenges of sustainability. Within these four broader themes, the author critically examines management strategies towards compliance and labour productivity, transnational governance, buyer-supplier relationships, and power dynamics. This book is the first to explore management's perceptions of workers, buyers, and government through an analysis of four factories which demonstrate the role of mid-level management, how supervisors treat production workers, workers' impact on innovation, welfare programmes as well as CSR policies, and the impact of COVID-19. Offering new perspectives on Bangladesh's garment export industry, this book will be of interest to researchers in the field of policy studies, labour studies, South and South-East Asian studies, development studies, international trade, and political science.

Chapters written by foremost international experts in their fields Editors' notes written for classroom use and background information Figures and tables providing illustrations of important concepts Case studies delivering practicality and in-depth analysis to current events A special chapter on Covid-19 and its implications for the food system

Chapters written by foremost international experts in their fields Editors' notes written for classroom use and background information Figures and tables providing illustrations of important concepts Case studies delivering practicality and in-depth analysis to current events A special chapter on Covid-19 and its implications for the food system

Electrospinning of nanofibers has emerged as a specialized processing technique for the formation of sub-micron fibers, with high specific surface areas. Electrospinning of Nanofibers in Textiles presents important new research in the dynamic and emerging field of electrospinning and covers all aspects of the technology as used to produce nanofibers.

Food Science: Research and Technology presents a broad selection of new research in food science and reflects the diversity of recent advances in the field. Chapters include a study on the use of microbial enzymes for flavor and production in food production; studies of various natural foods, including litchi (lychee), pinto beans, and chickpeas; the content and antioxidant activity of dried plants; new applications of galactosidases in food products; a study of the medicinal properties of edible mushrooms; and more.

There is increasing interest in the area of protective vests, either for protection against bullets or protection from the most realistic threats within domestic frontline operations: edged weapon, knives, and medical needles. This volume addresses that need. This new book provides an in-depth survey of the state-of-the-art research and practical techniques in the area of protected fabrics, especially stab-resistant and bulletproof fabrics. The book covers: * The history of protective armor: the long history of the art of protective armor manufacturing. * Materials used for body armor: the design and materials used for soft armor to increase its perforation-resistance utilizing high-performance fibers. * Anti-stab and anti-bullet armor design: the different design parameters required for the design of flexible armor in order to stop high-velocity projectiles. * The comfort of the body armor design: the flexibility, thermal resistivity, and evaporative moisture resistivity through the fabric. * Methods of testing the flexible body armors: testing the components of flexible body armor, according to the level of the protection required, such as NIJ Standards, HOSDB Body Armour Standards for UK Police, and the German SK1 Standard, among others. Written by an expert in textile composite material engineering, this volume fills an important gap in the area of protective fabric against stabbing or bullets and provides invaluable practical knowledge for body armor design.

This new volume reviews recent academic and technological developments behind new engineered modified nanotextile materials. The developments in textiles using nanotechnology give ordinary materials improved properties, such as better water resistance, enhanced moisture and odor reduction, increased strength and elasticity, and resistance to bacteria, among other improvements. The research reported in this book presents state-of-the-art technology in modern materials with an emphasis on the rapidly growing technologies in textile engineering. Several innovative applications for different materials are described in considerable detail with emphasis on the experimental data that supports these new applications. From nano-fibers to chemical materials, creative modifications concerning new nanocomposites are described that could one day become commonplace. The book covers a host of topics in this area, including the design of new textile products, moisture and heat transfer in clothing, developments in electrospinning, new applications, nanotextile and tissue engineering from a biological perspective, and more. The book is intended for researchers and those interested in future developments in mechanical and physicochemical characteristics of modified nanotextile materials and polymer blends. The book will also be a useful tool for students and researchers, providing helpful insights into new evolving research areas in nanostructured polymer blends and composites in textiles.

Natural Fiber Textile Composite Engineering sheds light on the area of the natural fiber textile composites with new research on their applications, the material used, the methods of preparation, the different types of polymers, the selection of raw materials, the elements of design the natural fiber textile polymer composites for a particular end use, their manufacturing techniques, and finally their life cycle assessments (LCA). The volume also addresses the important issue in the materials science of how to utilize natural fibers as an enhancement to composite materials. Natural fiber-reinforced polymer composites have been proven to provide a combination of superior mechanical property, dielectric property, and environmental advantages such as renewability and biodegradability. Natural fibers, some from agricultural waste products, can replace existing metallic and plastic parts and help to alleviate the environmental problem of increasing amounts of agriculture residual. The book is divided into four sections, covering: applications of natural fiber polymer composites design of natural fiber polymer composites composite manufacturing techniques and agriculture waste manufacturing composite material testing methods The first section of the book deals with the application of textile composites in the industry and the properties of the natural fibers, providing an understanding of the history of natural fiber composites as well as an analysis of the different properties of different natural fibers. The second section goes on to explain the textile composites, their classification, different composite manufacturing techniques, and the different pretreatment methods for the natural fibers to be used in composite formation. It also analyzes the composite material design under different types of loading and the mechanism of failure of the natural fiber composite. The effect of the fiber volume fraction of different textile structures is explained. The third section of the book, on composite manufacturing techniques and agriculture waste manufacturing, concerns the natural fiber composite manufacturing techniques, agricultural waste, and the methods of their preparation to be used successfully in the composite, either in the form of fibers particles or nanoparticles. The book then considers the testing methods of the different composite components as well as the final composite materials, giving the principle of the testing standards, either distractive or nondestructive. This book attempts to fill the gap between the role of the textile engineer and the role of the designer of composites from natural fibers. It provides important information on the application of textile composites for textile engineers, materials engineers, and researchers in the area of composite materials.

First published in 1955, this book offers a detailed history from the past to the mid-20th century on economic control. The book examines economic competition, particularly regarding the British economic system, and Fogarty looks at its scope, as well as its limits. This analysis considers working conditions in the mid-20th century, examining the impacts of industry on the life and work of the British agricultural population. The book first examines production decisions, arguing that a systematic and periodic overhaul of control mechanisms are required. Fogarty goes to give a detailed analysis on decisions about industry objectives. Ultimately, a broader look is given on the wider economic setting, and the definition of the economist is itself examined, taking into account the wider role that economics played in 20th century society.

US Marine Corps Major General Smedley Butler collected an award cabinet full of medals for his battlefield bravery. But perhaps his bravest act of all was to declare, after his retirement in the early 1930s, who was really winning (and losing) during the bloody clashes. It was business interests, he revealed, who commercially benefited from warfare. War Is a Racket is the title of the influential speech Butler delivered on a tour across the United States, as well the expanded version of the talk that was later published in 1935 and is now reprinted here. This seminal piece of writing rings as true today as it did during Butler's lifetime. In his introduction, Jesse Ventura reviews Butler's original writings and relates them to our current political climate explaining how right he was, and how wrong our current system is. With an insightful new foreword by Salon.com founder David Talbot, and a new afterword by activist Cindy Sheehan, this portable reference will appeal to anyone interested in the state of our country and the entire world. Skyhorse Publishing, as well as our Arcade imprint, are proud to publish a broad range of books for readers interested in history--books about World War II, the Third Reich, Hitler and his henchmen, the JFK assassination, conspiracies, the American Civil War, the American Revolution, gladiators, Vikings, ancient Rome, medieval times, the old West, and much more. While not every title we publish becomes a New York Times bestseller or a national bestseller, we are committed to books on subjects that are sometimes overlooked and to authors whose work might not otherwise find a home.

Heartland Tobacco War chronicles the political and public relations battles between health advocates and forces supported by the tobacco industry in Oklahoma from the 1980s to the present. Michael S. Givel and Andrew L. Spivak draw on previously-suppressed tobacco insider documents and first-hand interviews with key players in the conflict. This story of pro- and anti-tobacco lobbying and legislation in the nation's heartland especially highlights the unique role of Oklahoma's "renegade" Department of Health Commissioner, Dr. Leslie Bietsch. After decades of political dominance by the tobacco industry, this single maverick bureaucrat in the early 2000s bypassed the usual insider politics of the legislature and employed aggressive public campaign strategies to bring about sweeping legal victories for clean indoor air and tobacco taxes in a very conservative state. The authors examine the Commissioner's aggressive advocacy in the context of insider and outsider policy advocacy, public administration ethics, the politics of bureaucratic activism and administrative lawmaking, and direct democracy. Heartland Tobacco War tells a story that will be of great relevance to public health practitioners, historians, health activists, health policy scholars, sociologists, public administration scholars, social movement and public interest group scholars, political scientists, public policy scholars, and anyone else interested in the politics of the tobacco industry.

This book provides an overview of evolving patterns of trade partnership with historical perspective. It presents changing requirements of industry competitiveness and explains the vital relationships between trade partnerships and industry competitiveness. As well, it further examines the interactive relationships between trade partnerships and industry competitiveness. In recent years, with decreasing strategic alliances among nations and less visibility of international governance mechanisms (e.g., WTO) and counter to globalization, preferential trade agreements and free-trade agreements have proliferated among nations. At the same time, industrial competitiveness is becoming a serious strategic policy priority of nations-both advanced and emerging economies. Theoretical discussion focuses on the practices of global network capabilities for the top of the pyramid (ToP) and base of the pyramid (BoP). Special focus is on trade partnerships and industry competitiveness in the Asian economies (China, Japan, South Korea, India, Indonesia), three ASEAN nations (Vietnam, Thailand, and Malaysia), and Mexico. Extensive industry and firm-level case studies discuss ToP and BoP interface capabilities in the form of manufacturing and services life-cycle management, which extends value creation and delivery of manufacturing and services. This extension integrates the cloud ecosystem, such as timely data/information/knowledge flows via the virtual world; and ground value chains, such as the flow of complex real goods and services in the visible world.

This textbook draws on the authors' experience gained by teaching courses for engineering students on e.g. vehicle mechanics, vehicle system design, and chassis design; and on their practical experience as engineering designers for vehicle and chassis components at a major automotive company. The book is primarily intended for students of automotive engineering, but also for all technicians and designers working in this field. Other enthusiastic engineers will also find it to be a useful technical guide. The present volume (The Automotive Chassis - Volume 1: Component Design) focuses on automotive chassis components, such as:* the structure, which is usually a ladder framework and supports all the remaining components of the vehicle;* the suspension for the mechanical linkage of the wheels;* the wheels and tires;* the steering system;* the brake system; and* the transmission system, used to apply engine torque to the driving wheels. This thoroughly revised and updated second edition presents recent developments, particularly in brake, steering, suspension and transmission subsystems. Special emphasis is given to modern control systems and control strategies.

Originally published in 1999 The Commercial Use of Biodiversity examines how biodiversity and the genetic material it contains are now as valuable resources. Access to genetic resources and their commercial development involve a wide range of parties such as conservation and research institutes, local communities, government agencies and companies. Equitable partnerships are not only crucial to conservation and economic development but are also in the interests of business and often required by law. In this authoritative and comprehensive volume, the authors explain the provisions of the Convention on Biological Diversity on access and benefit-sharing, the effect of national laws to implement these, and aspects of typical contracts for the transfer of materials. They provide a unique sector-by-sector analysis of how genetic resources are used, the scientific, technological and regulatory trends and the different markets in Pharmaceuticals, Botanical Medicines, Crop Development, Horticulture, Crop Protection, Biotechnology (in fields other than healthcare and agriculture) and Personal Care and Cosmetics Products. This will be an essential sourcebook for all those in the commercial chain, from raw material collection to product discovery, development and marketing, for governments and policy-makers drafting laws on access and for all the institutions, communities and individuals involved in the conservation, use, study and commercialisation of genetic resources.