In 1962, Masahiro Shima founded Shima Seiki, with the aim of developing a fully automated seamless glove-knitting machine. Following this success, the company expanded into flat knitting machines. However, the age of the computer brought a whole new era for Shima Seiki. By committing to computerization in its mainstream products, Shima Seiki gradually began to stand apart from its competitors. Shima Seiki's focus on computer-aided knit design and programming, in fact led to a revolution in the fashion industry. Written by the inventor himself, this book looks at how Masahiro Shima developed both the technology and philosophy to enable his company to be market leaders in industrial knitting machines - and fundamentally change the fashion industry. This culminated in the launch of the company's Wholegarment knitting machine in 1995, which altered forever the way knitted garments are produced, and which today is used by fashion manufacturers across the world.

This book provides a clear analysis of the multi-level impacts of the existing international law regime related to genetic resources on developing countries. It does so through a cogent exposition of the different areas of the law pertaining to genetic resources that are relevant and impact on people's rights and livelihoods. Its focus on equity is a welcome addition to the literature.' - Philippe Cullet, University of London, UK'Camena Guneratne's thought-provoking book critically evaluates the clash between the private property approach to genetic resources embedded in international intellectual property conventions, and the competing values embedded in a variety of other conventions and laws. She contests key assumptions behind intellectual property regimes supporting genetic commerce, distinguishing the genetic 'commons' from other types of resource. This book provides a comprehensive scholarly dealing with the topics noted in its title, but also should increase debate about policy failures in responding to the risks to the underprivileged of the instruments we use to pursue our economic interests of the majority.' - Paul Martin, University of New England, Australia 'This is a wonderful book. All to often in the quest to preserve biodiviersity, we forget that the equation of equity hs to be the forefront of the debates on sustainable development. Dr. Guneratne rectifies this mistake.This linkage between biodiversity, politics and international law is of such a high calibre, that it is likely that this work will become a key text for students and scholars alike.' - Alexander Gillespie, University of Waikato, New Zealand This book examines current developments in international law which regulate the uses of plant genetic resources for food and agriculture, and the various property regimes which are applied to these resources by these international agreements. In the current context of the global food crisis, the development and stability of national agricultural systems is an urgent concern, particularly among developing countries. This stability, and national food security, will potentially be threatened if these countries are unable to have free access to agricultural crop plants. This book analyses a range of international agreements including the recently adopted Nagoya Protocol and demonstrates that in their current implementation they favor private ownership of these resources rather than free access. The book takes the position that this is inherently inequitable and these resources should be maintained in the public domain. This book will be of use to a wide range of readers from students and scholars to those working in the fields of trade and intellectual property, human rights, environmental conservation and advocacy on international issues. It contains a rigorous legal analysis of current international law development on the issue based on the negotiations which have taken place in the relevant forums, and will therefore be particularly useful to lawyers and legal scholars. It is also written in an uncomplicated style which makes it readily accessible to non-lawyers and the case studies and empirical data used throughout the book adds to its interest.

In the 1970s, as car enthusiasts in the U.S. grew bored with models manufactured under tightening pollution and safety regulations, some innovative dealers exploited a legal loophole-designed to allow U.S. soldiers and diplomats to return from abroad with their vehicles-to import exotic cars never intended for sale in America. During the 1980s, a rise in the value of the dollar made car shopping in Europe a bargain hunter's dream. A network of unauthorized "gray market" dealers emerged, bypassing factory channels. Middle-class Americans suddenly found they could afford a Mercedes or BMW. These cars had to pass through U.S. customs, equipped to handle only a few independent imports annually. As applications ballooned, the regulatory system collapsed. This is the story of a misunderstood but fascinating period in the automotive industry, when creative importers found ways to put American motorists in new Ferraris while the EPA and DOT were backed up with mounds of paperwork.

A Mechanistic Approach to Medicines for Tuberculosis Nanotherapy examines drug carrier development for controlled, targeted, pH and stimuli responsive drug releases for tuberculosis. The book provides in-depth information about mycobacterium tuberculosis, tuberculosis formation, and synthetic procedures for carrier synthesis, characterizations and mechanistic approaches. Key topics include the properties and functions of nanomedicines and how they might be applied for clinical diagnosis and treatment. Emphasis is placed on the basic fundamentals, biomaterial formulations, design principles, fabrication techniques, and transitioning bench-to-bed clinical applications. This book is useful for new researchers who focus on nanomedicine, stem cell therapy and bone tissue engineering. In addition, it introduces experienced researchers and clinicians to key trends, thus increasing their knowledge in drug discovery for tuberculosis and nanomedicine.

Textiles and computing have long been associated. High volume and low profit margins of textile products have driven the industry to invest in high technology, particularly in the area of data interpretation and analysis. Thus, it is virtually inevitable that soft computing has found a home in the textile industry. Contained in this volume are six chapters discussing various aspects of soft computing in the field of textiles and apparel.

Harrison analyzes how the U.S. research pharmaceutical industry, faced with domestic political opposition to the prices it charged for prescription drugs, chose to pursue its policy goal of greater appropriability of its intellectual property through the institutions of foreign economic policymaking. As Harrison explains, a new body of literature has developed to analyze the emergence of intellectual property as a major international trade issue. For many researchers, the inclusion of trade related intellectual property (TRIPS) into the Uruguay round of the General Agreement on Tariffs and trade (GATT) negotiations marks an important demonstration of the political influence of U.S. knowledge-intensive industries. However, as he demonstrates, a more thorough specification of the domestic political environment reveals that the research pharmaceutical industry was incapable of achieving its domestic policy objectives at the same time that it is credited with immense international political power. By providing a theory of institutional choice, Harrison reconciles this incongruity. He explains the strategic choices of the research pharmaceutical industry as a function of the transaction costs associated with pursuing its policy objectives within a variety of institutional alternatives. He concludes that he internationalization of intellectual property rights was a result of the changing domestic political environment in which the research pharmaceutical industry found itself the loser in a series of domestic economic policy battles. A thoughtful analysis of particular important to scholars, researchers, and policy makers involved with international trade, intellectual property, the pharmaceutical industry, and public policy.

Pharmacy Practice Research Case Studies provides examples and details regarding how pharmacy practice research has transformed over the past decade and how this is impacting overall health. This book presents several methodologies and techniques used in current pharmacy practice. According to the United Nations Sustainable Development Goals, countries around the world are aiming to achieve Universal Health Coverage. In this context, pharmacists are a vital part of the healthcare teams and the book portrays the research methods used in conducting pharmacy practice and medicines use research. The professional role of pharmacists has evolved tremendously over the past few decades across the globe and the pace of change has been interestingly phenomenal in varying aspects. The book provides a great resource for pharmacists, pharmaceutical scientists, policymakers, and researchers to understand the dimensions of practice, education, research, and policy concerning pharmacy, and it provides the synthesis of the development so far, pointing to the needs and demands of the future.

Paper and the British Empire examines the evolution of the paper industry within British organisational frameworks and highlights the role of the Empire as a market and business-making area in a world of shrinking commerce and rising trade barriers. Drawing on a valuable range of primary sources, this book covers the period 1861-1960 and examines events from the establishment of free trade backed by the gold standard to Britain's membership of the European Free Trade Association. In the field of the paper industry, the speed and intensity of the industrialisation process around the globe have been shaped by a wide variety of variables, including the surrounding institutional framework; entrepreneurial and organisational strategies; the cost and accessibility of transport; and the availability of capital, knowledge, energy resources, and technology. The supply of papermaking raw materials has also been key and has historically been the most important determinant for geographical location and dominance. The research in this work focuses on the roles played by such variants, on the one hand, and demand characteristics on the other. In particular, it considers developments connected to a quest for Empire-grown raw materials in order to tackle the problem of the lack of indigenous raw materials and the resulting dependence on Scandinavian wood pulp imports. This text is of considerable interest to advanced students and researchers in economic history, business history, and the paper industry, and will also be useful to organisations working within the pulp and paper industries.

This book proposes that, within the automotive industry, revised marketing principles and innovative marketing strategies are needed to address more effectively the unprecedented challenges posed by the modern digital revolution. The starting point for these proposals is a thorough analysis of the evolution of marketing in the industry across three ages of technological innovations - the mechanical, the electronic, and the digital. The main objectives are first, to illustrate how study of the past can help carmakers as they move forward into the unknown, and second, to identify the main choices that they will face. The central premise is that unusual times call for unusual strategies. By mining the past in order to foresee likely future developments regarding competition and marketing strategies within the car industry, the book will appeal both to researchers and to present or future managers in the automotive and other innovation-driven sectors.

Henry Bernard Loewendahl scrutinizes the relationship between multinational companies, regional development, and governments, using a framework of bargaining between government and multinationals. He critically analyzes the role of foreign investment in economic development, and examines how governments can link inward investment to regional economic development. Based on extensive use of data, interviews and case studies of Siemens and Nissan's UK investment, the book shows why MNCs have invested in the UK in the past, how they bargained with the government, and what the impact was on the national and regional economies. In particular, through linking the strategy of multinationals to the location advantages of the UK, it is argued that labor flexibility and incentives were crucial to investment decisions. Loewendahl recommends a framework to integrate endogenous and exogenous approaches to developments; and proposes a greater role for the region and the EU to control incentives and monitor multinationals.

Food Waste Recovery: Processing Technologies, Industrial Techniques, and Applications, Second Edition provides information on safe and economical strategies for the recapture of value compounds from food wastes while also exploring their re-utilization in fortifying foods and as ingredients in commercial products. Sections discuss the exploration of management options, different sources, the Universal Recovery Strategy, conventional and emerging technologies, and commercialization issues that target applications of recovered compounds in the food and cosmetics industries. This book is a valuable resource for food scientists, technologists, engineers, chemists, product developers, researchers, academics and professionals working in the food industry.

Considering the Patient in Pediatric Drug Development: How Good Intentions Turned into Harm addresses a fundamental challenge in drug development and healthcare for young patients. In clinical trials and clinical practice, the term "children" is used ambiguously to confer physiological characteristics to a chronological age limit, which in reality does not exist. This book outlines why the United States (US) and European Union's (EU) regulatory authorities, pediatric academia, and the pharmaceutical industry demand, support and perform pediatric drug studies, along with the key flaws of this demand that blurs the different administrative and physiological meanings of the term "child." In addition, the book covers why most pediatric regulatory studies lack medical sense and many even harm young patients and the conflicts of interest behind pediatric drug studies. It includes relevant information about the maturation of the human body regarding absorption, distribution, metabolism and excretion of food and drugs as well as key differences between newborns, infants, older children and adolescents.

Drug Delivery Devices and Therapeutic Systems examines the current technology and innovations moving drug delivery systems (DDS) forward. The book provides an overview on the therapeutic use of drug delivery devices, including design, applications, and a description of the design of each device. While other books focus on the therapy, the primary emphasis in this book is on current technologies for DDS applications, including microfluidics, nanotechnology, biodegradable hydrogel and microneedles, with a special emphasis on wearable DDS. As part of the Developments in Biomedical Engineering and Bioelectronics series, this book is written by experts in the field and informed with information directly from manufacturers. Pharmaceutical scientists, medical researchers, biomedical engineers and clinical professionals will find this an essential reference.

The power of big business in the economy of the Third Reich remains one of the most important issues of that era. Drawing upon research, much of it in German corporate and government archives, Peter Hayes argues that IG Farben Chemicals, the largest corporation in Nazi Germany, proved consistently unable to influence national policy outside the narrow sphere of the firm's expertise. Indeed, as Hayes shows, the most infamous aspects of Nazi policy - the Third Reich's armaments and autarky drives during the 1930s, Germany's advance toward war, the pillaging of Europe, the exploitation of slave and conscript labor, and the persecution of the Jews - occurred despite IG Farben's advocacy of alternative courses of action. Nonetheless, Farben grew rich under the Nazi regime and was directly involved in some of its greatest crimes.

The PCP's Bicentennial Edition Remington: The Science and Practice of Pharmacy, Twenty Third Edition, offers a trusted, completely updated source of information for education, training, and development of pharmacists. Published for the first time with Elsevier, this edition includes coverage of biologics and biosimilars as uses of those therapeutics have increased substantially since the previous edition. Also discussed are formulations, drug delivery (including prodrugs, salts, polymorphism. With clear, detailed color illustrations, fundamental information on a range of pharmaceutical science areas, and information on new developments in industry, pharmaceutical industry scientists, especially those involved in drug discovery and development will find this edition of Remington an essential reference. Intellectual property professionals will also find this reference helpful to cite in patents and resulting litigations. Additional graduate and postgraduate students in Pharmacy and Pharmaceutical Sciences will refer to this book in courses dealing with medicinal chemistry and pharmaceutics.

This book explores sustainability within manufacturing enterprises and examines the concepts and principles of this field. It also reviews the quantitative and qualitative tools available for analytic assessment. It presents a new framework for sustainable manufacturing requirements and discusses the implementation of sustainable manufacturing in terms of practices, indicators, and sustainability level assessments. The book also details the important conditions necessary for the conversion of existing traditional plants to ones with more sustainable processes. Chapters explore topics including the assessment of economic sustainability, social sustainability, environmental sustainability, sustainable manufacturing practices, and sustainability optimization. Serving as a reference for engineers, managers, and practitioners involved in manufacturing, this book will also be a valuable resource to students and researchers of industrial engineering, manufacturing engineering, systems engineering, and operations management.

The fourth edition of Gambero Rosso's Top Italian Food & Beverage Experience features a selection of the best Italian food and beverage producers. This is the only guide in the sector classified according to product category to bring together over 1200 exceptional entities ready and willing to export a range of quality items. The guide includes a section on the best fresh fruit and vegetables, indicating the relative producer consortia and associations, making it an indispensable tool for foodies, but especially for industry players wanting to promote the best of 'Made in Italy', and for the 50,000 buyers who participate annually in Gambero Rosso's international events.

Exclusive title focussing on various elements of combing in spinning. Includes detailed functioning of conventional and modern combers. Explains various motions in combing pertaining to diferent timings. Discusses role of modern electronics in controlling the mechanisms and offering on-line controls. Features solved examples at the end to tackle problems at shop-floor level.

How food marketers make use of key variables--such as innovation; target market; market segmentation; image; and physical, environmental, and human resources--determines how successfully they sell their products. Michman and Mazze concentrate on the food industry as they examine what contributes to a successful marketing campaign. The authors discover that not all variables have to be used concurrently; some may be more important than others depending on environmental conditions, and the effective use of one variable may cancel the ineffectiveness of another. By focusing on the key variables to use in a volatile economic environment, by emphasizing lessons learned from both marketing successes and failures, and by demonstrating how to adapt key variables to changing conditions, Michman and Mazze help executives ensure the success of their marketing efforts.

Mazze and Michman examine 10 institutional formats in the American food marketing and distribution structure--supermarkets, fast-food, ice cream, soup, breakfast cereal, baby food, ethnic food, snack food, candy and soft-drinks. The supermarket industry is analyzed first with an overview of food marketing and distribution. Specific industries are then analyzed using the five key variables (innovation, image, target market, physical environment, and human resources) with a historical framework to help managers learn from past marketing mistakes. The authors emphasize that avoidance of past mistakes is essential for sound marketing strategy, a fact illustrated by the examples of companies afflicted by injuries who have disregarded this advice.

`A splendid analysis of how an automotive industry based on mass production has become an alien in our time - where diversity and personalised products and services have become the norm. Peter Wells presents an intriguing analysis of how the automotive industry can find ways forward and re-invent itself. A must read for all interested in sustainable mobility, as well as strategists in the automotive industry.' - Arnold Tukker, TNO Built Environment and Geosciences, The Netherlands `The Automotive Industry in an Era of Eco-Austerity examines how we can achieve sustainable personal mobility, using a wide range of ideas and concepts. As the author stresses, this is not about the search for the best single technology for developing a sustainable car - it is much wider than that. Rather this book is about the fact that fundamental change is needed. Anyone interested in the auto industry should read it - much recommended.' - David Bailey, Coventry University, UK `What the global automotive industry needs right now is ideas and this book is packed with them. Dr Wells is a master of turning a topic on its head in order to approach it from an angle that is both unique and enlightening. This book should be required reading for decision makers within the automakers, suppliers and governments, whose job it will be to shape the auto industry of tomorrow.' - Gareth Owen Davies, AutomotiveWorld.com The Automotive Industry in an Era of Eco-Austerity analyses the future prospects of the largest manufacturing sector in the world, the automotive industry, at a time of unprecedented global financial crisis and unrelenting environmental pressure. This unique book seeks to combine economic analysis with the environmental research to arrive at a comprehensive understanding of the forces that shape change in the automotive industry. It eschews the usual focus on technologies, and gives more attention to the impact of change on the business models and strategies adopted by the vehicle manufacturers, the scope for new entrants, and the implications for policy-makers. This richly textured book concludes that the achievement of a sustainable automotive industry will not be possible with `one best way', but that myriad technologies and business concepts, grounded in the distinct needs of different places and consumers, will be the basis of the future of mobility. Drawing on a wealth of industry data by virtue of the authors' record of many years researching the industry, this book will be invaluable to both students and researchers working within transport, industrial ecology, automobility, industrial policy, economics, regional development, sustainability, technology, and business models.

A 2017 Michigan Notable Book After World War II, the American automobile industry was reeling. Having spent years building tanks and airplanes for the army, the car companies would need years more to retool their production to meet the demands of the American public, for whom they had not made any cars since 1942.    And then in stepped Preston Tucker. This salesman extraordinaire from Ypsilanti, Michigan, had built race cars before the war, and had designed prototypes for the military during it. Now, gathering a group of brilliant automotive designers, engineers, and promoters, he announced the creation of a revolutionary new car: the Tucker '48, the first car in almost a decade to be built fresh from the ground up. Tucker's car would include ingenious advances in design and engineering that other car companies could not match. With a rear engine, rear-wheel drive, a safety-glass windshielf that would pop out in case of an accident, a padded dashboard, independent suspension, and automatic transmission, it would be more attractive and aerodynamic—and safer—than any other car on the road.    But as the public eagerly awaited Tucker's car of tomorrow, powerful forces in Washington were trying to bring him down. An SEC commissioner with close ties to Detroit's Big Three automakers deliberately leaked information about an investigation the agency was conducting, suggesting that Tucker was bilking investors with a massive fraud scheme. Headlines accused him a perpetrating a hoax and claimed that his cars weren't real and his factory was a sham.  In fact, the Tucker '48 sedan was genuine, and everyone who saw it was impressed by what this upstart carmaker had achieved. But the SEC's investigation had compounded the company's financial problems and management conflicts, and a superior product was not enough to keep Tucker's dream afloat.  Here, Steve Lehto tackles the story of Tucker's amazing rise and tragic fall, relying on a huge trove of documents that has been used by no other writer to date. It is the first comprehensive, authoritative account of Tucker's magnificent car and his battles with the government. And in this book, Lehto finally answers the questions automobile aficionados have wondered about for decades: Exactly how and why was the production of such an innovative car killed?

This book examines Foreign Direct Investment of major Korean automotive companies in Europe, with particular reference to how economic integration has affected the motivations and patterns of FDI and industrial location. The book is a valuable source of information on FDI, the automobile industry in Europe and South Korea and business decision-making process in general.