On economies of scale during the nineteenth century, much is assumed, but little is known. This study, first published in 1985, seeks to close this gap in our knowledge by providing comprehensive empirical evidence on the status of economies of scale in mid-nineteenth century manufacturing industry. This evidence is in the form of production function estimates made using data from the manuscripts of the federal censuses of manufacturing for 1850, 1860 and 1870.

The Silicon Dragon is a systematic study of the growth of high-tech giants in the Greater China Region, depicting the success story of the microelectronics industry in Taiwan. Literature and studies on Taiwan's success are surprisingly limited, and this book aims to fill this gap, addressing questions such as: How has Taiwan achieved such an outstanding performance in the information industry? How did Taiwan obtain and maintain its competitive advantage? What was the secret of success? What role did the government and manufacturers play during the development process? What insights can newcomers gain from these achievements? The book examines the government policies that acted as catalysts to the growth of high-tech industries in Taiwan, along with the roles of high-tech 'incubators' and government-administered science parks. The authors provide case studies of high profile companies including Acer, Philips Semiconductors and Macronix International, and interviews with key decision makers to highlight the corporate strategies adopted in response to government policies and global commercial demand. Finally, insightful narratives on the birth and growth of a government-fostered strategic industry are provided, as is a synopsis of the Asian contribution to the evolution of the global microelectronics development. This book will strongly appeal to academics, researchers and students with an interest in engineering, technology and business management. Business managers and government officials will also find much to interest them in this book.

This title was first published in 2000: Steven Nivin analyzes a process vital to economic development - technological change. He furthers understanding of the processes driving innovation, so that we may gain a deeper insight into the development of economies. Specifically, the study explores the concept of innovation potential and the factors that result in variations in innovation potential across metropolitan areas, using the US machine tool industry as a case study. To provide a comparison, the same models are also estimated for the semiconductor industry. The findings indicate that urbanisation economies, localization economies, human capital, universities, and invention-derived knowledge are significant factors. The study assesses the contributions of three different skill levels of human capital; college-educated, graduate degree, and locally produced PhD's in mechanical and electrical engineering. Only the graduate and PhD degree measures are found to be significant, indicating the importance of having a highly skilled pool of labour within the region. The influences of the factors appear to be similar across industries, with some slight differences. The transfer of knowledge through patents is also studied. It is found that the transmission of this knowledge is slower between different industries, relative to the transmission within the same industry.

This well-known QA manual has been updated to provide the guidance readers need to assess their compliance with standard regulations. This Volume 2 of a three-part package contains the full text on: * FDA regulations * EC and IPEC guidelines * ISO/BSI standards referenced in the checklists furnished in volume 1 Easy-to-read and organized to provide fast access to guidelines and regulations, this is an essential reference for those working in the field.

The pharmaceutical industry is under increasing pressure to do more with less. Drug discovery, development, and clinical trial costs remain high and are subject to rampant inflation. Ever greater regulatory compliance forces manufacturing costs to rise despite social demands for more affordable health care. Traditional methodologies are failing and the industry needs to find new and innovative approaches for everything it does. Six Sigma in the Pharmaceutical Industry: Understanding, Reducing, and Controlling Variation in Pharmaceuticals and Biologics is the first book to focus on the building blocks of understanding and reducing variation using the Six Sigma method as applied specifically to the pharmaceutical industry. It introduces the fundamentals of Six Sigma, examines control chart theory and practice, and explains the concept of variation management and reduction. Describing the approaches and techniques responsible for their own significant success, the authors provide more than just a set of tools, but the basis of a complete operating philosophy. Allowing other references to cover the structural elements of Six Sigma, this book focuses on core concepts and their implementation to improve the existing products and processes in the pharmaceutical industry. The first half of the book uses simple models and descriptions of practical experiments to lay out a conceptual framework for understanding variation, while the second half introduces control chart theory and practice. Using case studies and statistics, the book illustrates the concepts and explains their application to actual workplace improvements. Designed primarily for the pharmaceutical industry, Six Sigma in the Pharmaceutical Industry: Understanding, Reducing, and Controlling Variation in Pharmaceuticals and Biologics provides the fundamentals of variation management and reduction in sufficient detail to assist in transforming established methodologies into new and efficient techniques.

Tavistock Press was established as a co-operative venture between the Tavistock Institute and Routledge & Kegan Paul (RKP) in the 1950s to produce a series of major contributions across the social sciences. This volume is part of a 2001 reissue of a selection of those important works which have since gone out of print, or are difficult to locate. Published by Routledge, 112 volumes in total are being brought together under the name The International Behavioural and Social Sciences Library: Classics from the Tavistock Press. Reproduced here in facsimile, this volume was originally published in 1951 and is available individually. The collection is also available in a number of themed mini-sets of between 5 and 13 volumes, or as a complete collection.

This book examines the political economy of attempts to restructure the Donbass, one of the Soviet Union's most important 'old economy' 'rustbelt' industrial regions. It shows how local interest groups have successfully frustrated the central government's and the World Bank's proposed market-oriented restructuring, and how a manufacturing-based regional economy is surviving, partially, with restructuring postponed.

Like any book, this one is part of a dialogue. Over the years, I have asked thousands of questions, of myself and others, and tried to answer some. Out of all this discussion, a written pattern has grown. It is certainly not a definitive pattern. Among those whose words have been woven into it, there are many who might have fashioned it better. There are some who would have selected different colors and textures, or who might have preferred a totally different pattern. I am conscious of their voices and wish that I could adequately present them all. First and foremost are the voices of farmers and other villagers, whose experiences I have tried to understand and represent. A few of them will read this book and decide whether I learned anything from all their patient answers. If they were so inclined, they could tell more about the subject than I ever can.

Providing methodologies that can serve as a reference point for new formulations, the second volume covers uncompressed solids, which include formulations of powders, capsules, powders ready for reconstitution, and other similar products. Highlights from Uncompressed Solid Products, Volume Two include: the fundamental issues of good manufacturing practices formulations for more than 400 pharmaceutical products, including currently approved products and innovative products such as small proteins, instantly liquifiable powders, and nanoparticles access to US FDA guidelines, as well as all major guidelines around the world identification and inclusion of the most often approved capsules and powders in the US

This book examines the experiences of the globalizing Korean automobile industry, with particular focus on the Hyundai Motor Company (HMC), one of the most prominent of the new Korean multinational corporations. It provides an overview of the changing nature of the global automobile industry, before considering in depth the globalization processes that the Korean automobile industry has undertaken.

Tracing the development of HMC as it recovered from the failure of its first venture overseas, in Canada, and tried again in India, the authors explore the similarities and differences between the practices which HMC implemented in India and Korea. They highlight the importance of production systems and employment relations as part of HMC's growth, and argue that if Korean companies such as HMC are to compete successfully as global automobile producers they will need to increase the proportion of overseas production, establish global supply chains and improve co-ordination between head office and subsidiaries.

Based upon extensive fieldwork in India and Korea, this book is a detailed account of the globalization of the Korean automobile industry and Hyundai Motor Company. Its findings will be of importance to all those who seek to understand the challenges faced by firms that attempt to become global players.

Vast global resources are ploughed into the delivery of treatment interventions ranging from diet and lifestyle advice to complex surgery. In all cases, whatever the intervention, unless the recipient is engaged with the process and understands why the intervention has been offered and the part they play in its success, compliance is an issue. Even where the individual does engage and understand, he or she may choose not to comply. Non-compliance is estimated to cost the pharma industry US$70 billion per year. No figures exist for the cost to healthcare insurers and public health but non-compliance is undoubtedly one of the top five issues facing both drug developers and healthcare providers. During clinical trials, non-compliance undermines the accuracy of the data generated from the whole trial as well as particular aspects such as the efficacy of different dosages. This book explores the key factors which drive compliance and the part that healthcare professionals can play in improving this, with the key underlying goal of improving public health in its broadest sense.

For all those who love boats, their 'lines' are an essential element in the appreciation of individual craft. But what are these lines and how are they created? This book introduces the reader to the key principles of yacht design in a straightforward and understandable manner, allowing them to be aware of the elements and processes involved. Most of the complex maths has been replaced with simple rules of thumb. Any boat owner will benefit from understanding the characteristics of boat design which will help them if they want to modify the hull, rig, deck layout or accommodation. It will be equally useful to boat buyers who want to ask questions like: "How will she sail?"; "How much will she cost?"; "How easy is it to change things?" and "How can I reduce or increase sail area without upsetting the balance?" Boat owners and buyers will be able to feel more confident when talking to designers and boatbuilders about their current or future boat. While novice boat designers can start their journey with this book, giving them a good foundation whether they want to use pencil and paper or Computer-Aided Design. So, if you are any of the above, or simply have an interest in yacht design, this is the book for you!

For the last three decades, social historians who studied early America expanded older interpretations of colonial economy and society to include family, social position and gender as legitimate topical themes. During that same period, economic scholars have used social historians' community and household studies to explore rural self-sufficiency, the development of commercial agriculture and the Atlantic sea trade. Despite the recent use if family household economics to explore and explain colonial economy and society, most have entirely neglected one of the most fundamental early American industries: domestic textile production.
Colonial historians have previously used information about wool, flax and hemp in broad based arguments about the productive side of the colonial economy, yet few have considered textile production a significant colonial economic activity. As a result, textile-producing networks, construed as either economics or social phenomenon, have largely gone unnoticed.
This study draws from a broad array of sources including the probate inventories of Essex and Suffolk County, Massachusetts, extant account books, trial transcripts, court records and material culture. Combined with a working knowledge of cloth-making, those records reveal that domestic textile production was a major form of social organization, especially in early Massachusetts. Textile-reproducing networks clearly served to draw households, neighborhoods and regions together in particular ways. From the processing of fibers to the finishing of cloth, intense cooperation and an extensive system of corporate labor were key elements of textile production. Simply put, no one gender or age wasresponsible, rather a confluence of females and male as well as young and old laborers were necessary to the ensure the success of the industry.

This book integrates the experimental procedures and theoretical principles for undergraduate, postgraduate, academicians and researchers in the area of agriculture and life sciences. The experiments have been updated and extended to reflect developments in the respective fields. In-text worked examples are again used to enhance student’s understanding of each topic. The book is designed to provide students with the experience of how scientists use their knowledge to understand real-world science related issues that confront them in their professional lives. Experimental procedures and troubleshooting of data are emphasised throughout the book. The book integrates theory and practices to ensure students understand why and how each technique is used.

From Physick to Pharmacology addresses the important, albeit neglected history of the distribution and sale of medicinal drugs in England from the sixteenth to the twenty-first century. The social history of early medicine and the evolution of British retailing are two areas that have attracted considerable attention from academics in recent years. That said, little work has been done either by medical or business historians on the actual retailing of drugs. This book merges the two themes by examining the growth in the retailing of medicinal drugs since late-medieval times. The six academics contributing essays include both medical and business historians who provide an informed and stimulating perspective on the subject. After an introduction setting out the context of drug retailing and surveying the current literature, the volume is arranged in a broadly chronological order, beginning with Patrick Wallis's study of apothecaries and other medical retailers in early modern London. The next chapter, by Louise Hill Curth, looks at the way the distribution network expanded to encompass a range of other retail outlets to sell new, branded, pre-packaged proprietary drugs. Steven King then examines various other ways in which medicines were sold in the eighteenth century, with a focus on itinerant traders. This is followed by pieces from Hilary Marland on the rise of chemists and druggists in the nineteenth century, and Stuart Anderson on twentieth-century community pharmacists. The final essay, by Judy Slinn, examines the marketing and consumption of prescription drugs from the middle of that century until the present day. Taken together, these essays provide a fascinating insight into the changes and continuities of five centuries of drug retailing in England.

Military Industry and Regional Defense Policy re-examines military industrialization in the developing world, focusing on policy-making in producer states and the impact of security perceptions on such policy-making. Timothy D. Hoyt reassesses the role of regional state sub-systems in international relations, and recent historical studies of international technology and arms transfers. Looking at Israel, Iraq and India, the three most powerful regional powers in the Cold War era, he presesnts an expert analysis of the three-sided phenomena of the regional hegemony, the regional competitor and the small over-achiever. This new book breaks away from existing literature on military industries in the developing world, which has focused on their economic and development costs and benefits. These past studies have used primitive methodologies that focus on the production of complete weapons systems - a misleading gauge in a world of growing international defense cooperation. They have also ignored empirical evidence of the impact of local military industrial production on Cold War regional conflict, and of the defence planning and concerns that drove development of indigenous military industries in key regional powers. This new text delivers an incisive new perspective.

Marine accidents can occur at any time and everywhere in the world, resulting in loss of life, property, environment and reputation of the companies involved. Preventing accidents and establishing a safer world without accidents is an important agenda for the maritime industry. Since the enforcement of the International Safety Management Code in 1998, companies have taken various kinds of measures to prevent accidents. Unfortunately, measures have been undertaken in a disorganized manner, and have not been effective. Experts of risk management, the safety management system, and accident models have each undertaken accident preventive measures within the scope of their specific fields, but have not looked beyond the realm of their own fields. This book discusses systematic accident prevention by integrating multi-disciplinary expertise based on academic research, the quality management system which has already proved its effectiveness in other fields, and findings of the author's research. In systematic accident prevention, the weaknesses of a system within which accidents and incidents have occurred are viewed by combining scientific accident investigation data based on the International Maritime Organization model and the accident model. The nature of every type of marine accident, such as collisions, groundings, occupational casualties, etc., are derived by combining the accident model and statistical data. System weaknesses are rectified by the risk reduction method of risk management, and the rectified performance is incorporated in improvement in the system by the PDCA cycle, which is the core of the Safety Management System. We can see the weakness in the system and reduce the number of accidents and incidents while utilizing limited resources optimally to prevent accidents and incidents.

Why have Africans not gained a more dominant position in urban manufacturing in Kenya? This question is explored through an analysis of the institutions, both formal and informal, that have affected patterns of capital accumulation in Kenya by the African and Asian (Indian) communities. Using a new institutional economics approach, this book explores the history of economic activity through the pre-colonial, colonial and post-colonial periods, including the transformative period of British rule. During the colonial period, Asians were brought in to build the railways and subsequently focused on urban-based activities. Africans, meanwhile, found it difficult to move out of agriculture. Thus, the ethnic-sectoral division of activities was entrenched by the formal laws and powers of the British. Following independence, the network and financial capital that Asians had built up allowed them to survive early attempts at the Africanization of industry. Africans, now supported by the formal institutions of the state, still found it difficult to engage in manufacturing because they lacked the informal networks that support trade and credit. The analysis is supported by the results of a contemporary survey of 120 manufacturing firms in Nairobi's metal sector that highlight the division between smaller African firms and larger Asian ones.

There are competing theories to explain the reasons behind the international competitiveness of manufacturing in Asia. Analysing these different theories will bring important lessons, not just for Asia, but for developing economies the world over. This lucid book studies industries and firms in East Asia and examines the major determinants of their economic performance. With contributions from such leading thinkers as Ha-Joon Chang and Rajah Rasiah, the book covers such themes as: *industrial policy and East Asia *Taiwan's information technology industry *The role of the government in technological capability building Manufacturing Competitiveness in Asia touches on many important themes and issues and as such will be of great interest to students, academics and policy-makers involved in industrial economics, international trade and Asian studies.

This book is one of the first critical analyses of the automobile industry in India. It studies the sector in general and the passenger car industry in particular, and provides valuable insights into the operation of Foreign Direct Investment (FDI) companies in a technology-intensive industry under changing economic regimes. The volume underlines the influence of the changing nature of foreign investment, the impact of economic reforms, technology regimes and industrial policy on growth, structural changes and development. It offers a detailed account of the trade performance of manufacturers in India's passenger car industry. It also looks at successful cases to draw policy lessons towards encouraging quality FDI and developing India as a base for world production. A useful addition to industry studies in India, this book with its wide coverage and contemporary analyses will interest scholars and researchers of economics, Indian economy and industrial policy, industrial economics, automobile industry and manufacturing sector, development economics and international economics. It will also appeal to policymakers, practitioners and industrial associations.

This Second Edition examines the mechanisms and means to establish regulatory compliance for pharmaceutical products and company practices. It focuses on major legislative revisions that impact requirements for drug safety reviews, product regulatory approvals, and marketing practices. Written by top industry professionals, practicing attorneys, and FDA regulators, it includes policies and procedures that pharmaceutical companies need to implement regulatory compliance post-approval. New chapters cover: the marketing of unapproved new drugs and FDA efforts to keep them in regulatory compliance pharmacovigilance programs designed to prevent widespread safety issues legal issues surrounding the sourcing of foreign APIs the issues of counterfeit drugs updates on quality standards

Volume 40.3 of the journal Textiles Progress, this book describes advanced technical textiles products according to the application fields of the fiber materials. Although it does not cover all of the end-uses, the book contains major parts of advanced technical textile products, including products for resources and environmental issues, automobiles, medical and protective uses, information technologies, civil engineering, and electronics textiles.

Today's fast-paced manufacturing culture demands a handbook that provides how-to, no-holds-barred, no-frills information. Completely revised and updated, the Handbook of Manufacturing Engineering is now presented in four volumes. Keeping the same general format as the first edition, this latest edition not only provides more information but makes it more accessible. Each individual volume narrows the focus while broadening the coverage, giving you immediate access to the information you need. Volume Three, Parts Fabrication: Principles and Process discusses efficient deductive and systematic approaches to machine debugging while providing a refresher on the principles of structural mechanics. Edited by Richard Crowson with contributions from experts in each field, the book focuses on establishing communication between manufacturing and design engineers and machine-building technicians. The discussions of engineering design fundamentals, free-body diagrams, stresses, forces, and strength of materials help readers understand and solve counter-intuitive problems. The coverage includes material characteristics of metals, conventional fabrication processes, laser welding, modeling, and nontraditional machining methods. Assisting design engineers and machine builders in the successful execution of their tasks, the book recommends steps to improve technical problem solving and communication techniques. It provides understanding of how to incorporate deductive reasoning, systematic engineering, human interaction, and corporate cultural influences into manufacturing processes.

Today's fast-paced manufacturing culture demands a handbook that provides how-to, no-holds-barred, no-frills information. Completely revised and updated, the "Handbook of Manufacturing Engineerin"g is now presented in four volumes. Keeping the same general format as the first edition, this second edition not only provides more information but makes it more accessible. Each individual volume narrows the focus while broadening the coverage, giving you immediate access to the information you need. Volume One, Product Design and Factory Development reveals how human factors deeply affect productivity in the workplace and why the modern manufacturing engineer must be well versed in these areas.

Edited by Richard Crowson with contributions from experts in each field, the book considers historical data for anthropometry and explores the impact of injuries, product liability, and low productivity on product cost. The book sequentially outlines the basic concepts of reliability theory in six chapters along with commonly used statistical methods for evaluating component reliability. It covers rapid prototyping, explores the machine debugging and troubleshooting process, and devotes an entire chapter to computers and controllers.

The challenges presented by the fiercely technical world we live and work in are met by the manufacturing engineer. Companies can no longer afford to allow the manufacturing engineer to learn on the job. Therefore, the manufacturing engineer must gain as much knowledge from as many credible sources as possible. Covering the global picture of manufacturing, this book shows you how to successfully apply manufacturing engineering skills on the job.

China today has the largest communist political regime and one of the most dynamic, fastest-growing, and largest economies in the world. Using a case study of China's tobacco industry, this book analyses how the Chinese government was able to cultivate big state-owned firms that have successfully embraced the global market. The success of the Chinese economy and the many state-owned firms within it have given rise to a "Beijing Consensus," challenging almost every principle enshrined in the so-called "Washington Consensus" that espouses private ownership, free markets, and democracy. By examining two important political processes in contemporary China, 'local state competition' and 'global-market building', the book argues that the first process serves as a crucial basis for the second. It illustrates how the local governments involved themselves in building and shaping the tobacco market throughout the 1980s and 1990s, and how these domestic market dynamics created conditions for China's recent embrace of the international market. Offering an in-depth exploration of the political-economic processes in a key Chinese state industry, the book emphasizes that the key to understanding China's political transition is to look at how the state has been shaped by its market-building projects both domestically and globally. It presents an important contribution to studies on Chinese Business and International Political Economy.