Pharmaceutical Economics begins with an investigation of the structure of the industry and its three main components: the research firms which produce innovative products; the generic drug industry and its expanding role; and the biotech industry, which is regarded as the future for pharmaceuticals. Further sections discuss topics including demand and incentives, pricing and regulation. Professor Comanor and Professor Schweitzer have selected the most significant articles by leading academics, in order to offer a blend of standard economic interpretations of pharmaceutical policy and important new topics including biosimilars, insurance coverage for pharmaceuticals, price-fixing and direct-to-consumer advertising. An authoritative new introduction by the editors provides an insightful guide to these important topics.

International competitiveness is a prime concern of food industries and governments around the world as they have come to recognize that freer markets pose new threats and offer new opportunities. This book provides a review of the current thinking on competitiveness, encompassing ideas from Porter's "Diamond of Competitive Advantage", Balassa's "Revealed Comparative Advantage", Dunning's analysis of international business, Italian analysis of industrial districts and Boston Consulting Group approaches. Issues raised will be addressed through six European case studies, chosen to provide representation in terms of food product sector, orientation and country type.

A solid, rigorous, yet comprehensible analysis of process capability indices, this work bridges the gap between theoretical statisticians and quality control practitioners, showing how an understanding of these indices can lead to process improvement.

1) This is a comprehensive book on creative industries in India. 2) The book contains essays with recent data and multiple crucial case studies from across India. 3) This book will be of interest to departments of development studies, South Asian studies and cultural studies across UK.

This book examines the application of key elements of the Japanese Production System to five East Asian countries whose social and managerial environments differ from each other as well as from those of Japan. To analyse the key elements, a working model was constructed and applied. Using this model, these Japanese plants are also compared with those in the US where a previous study was undertaken. It includes contributions from leading researchers and academics.

This path-breaking book addresses the ongoing implications for traditional pharmaceutical companies and biopharmaceutical start-ups of the realignment of the industry knowledge-base. The theoretical approach draws on the modern theory of the firm and related ideas in order to better define the concept of the business model, which is employed to guide the case studies and empirical analysis in the book. The author shows that while traditional pharmaceutical companies have successfully adjusted their business models to meet the challenges of biotechnology, biopharmaceutical start-ups have experienced more problems. Despite the poor financial performance of the vast majority of these firms, the biopharmaceutical sector as a whole has created significant value. However, this has been captured disproportionately by a handful of large, fully-integrated biopharmaceutical firms and, to a lesser extent, by the largest dozen pharmaceutical companies.This highly focused book will be a captivating read for innovation and biopharmaceutical industry analysts, as well as advisers formulating policies to support the development of the biopharmaceutical sector. Academics working on innovation and biotechnology, as well as scientists engaged in research in the life sciences, will also find this book of particular interest.

This book presents applications of blockchain technologies to foster sustainable development in the textile and clothing supply chain. The concept of Textiles and Fashion Sustainability has grown to a wider extent today. Among the list of items to achieve Sustainability in Textiles and Fashion, the key element is the traceability of supply chains in terms of mapping and tracing the entire supply chain to ensure sustainable supply chain management. Reliable and transparent, efficient data is one of the crucial requirements for Textiles and Fashion Sustainability in today's advanced industrial context and this is possible in this advanced era by various technological advancements such as Block chain technologies. These days one can see a widespread application of blockchain technology in the Textiles and Clothing sector. The core competencies of blockchain technology namely transparency, data auditability, privacy, value transfer, and process efficiency and automation are very much essential for achieving the multifold objectives under the theme Textiles and Fashion Sustainability.

Energy consumption is of great interest to manufacturing companies. Beyond considering individual processes and machines, the perspective on process chains and factories as a whole holds major potentials for energy efficiency improvements. To exploit these potentials, dynamic interactions of different processes as well as auxiliary equipment (e.g. compressed air generation) need to be taken into account. In addition, planning and controlling manufacturing systems require balancing technical, economic and environmental objectives. Therefore, an innovative and comprehensive methodology - with a generic energy flow-oriented manufacturing simulation environment as a core element - is developed and embedded into a step-by-step application cycle. The concept is applied in its entirety to a wide range of case studies such as aluminium die casting, weaving mills, and printed circuit board assembly in order to demonstrate the broad applicability and the benefits that can be achieved.

Did food poisoning play a role in the Salem witch trials, leading to the hanging of nineteen men and women? Which poison recently laced the food of Russian ex-KGB agent Viktor Litvinenko, and how did it kill him? In Death in the Pot, internationally renowned food expert Morton Satin documents several culinary mishaps and misdeeds in an engrossing narrative that spans the ancient world to the present day. Historic events both tragic and bizarre have resulted from adulterated food. In the fifth century BCE, the great plague of Athens, probably caused by contaminated cereals, led to the defeat of the Athenians in the Peloponnesian War. In the prescientific Middle Ages, illnesses resulting from contaminated food were often attributed to the wrath of God or malevolent spirits. Heavily infectious ergot induced a spasmodic muscle condition, which the Church named "St. Anthony's Fire" and interpreted as retribution by God on heretics. Similarly, in seventeenth-century America the hallucinogenic symptoms of moldy grain were thought by Puritans to be signs of witchcraft. Even the madness of King George III, which played a role in the American Revolution, may have been induced by accidental arsenic poisoning. In the twentieth century, Satin recounts the efforts of modern industrial societies to make food safer; in some cases these efforts were heroic. For example, in the early days of the Food and Drug Administration a "Poison Squad" was formed, consisting of young scientists who willingly acted as guinea pigs to test the toxic effects of chemical additives. Today, the government has focused on the hazards of food bioterrorism. Satin concludes by describing measures taken to protect the public from intentional and unintentional poisoning, as well as recounting recent poisoning incidents. Both a fascinating glimpse into history from a unique angle and an authoritative reference work on food safety, Death in the Pot offers entertaining and informative reading for laypersons as well as experts in food technology and public health.

Around the world, food has probably never been as safe as it is today. However, periodic crises have aroused consumer anxiety and contributed to a general lack of confidence in the agro-industrial system. The diverse nature of these crises increases governments' and industry difficulties in predicting and tackling them. This book addresses the relations between risk and food theoretically and empirically through case studies from Japan and China. Part I of the book examines the interaction between theoretical aspects and decision-making. The book theorizes the links between food and risk and analyses the decision-making process in light of risks and governance. The relationship between food risks, governance systems and economic decisions is assessed to explore ideas such as the "pact of nutrition" and the theory of weak signals. Part II examines case studies from China and Japan in the aftermaths of recent crises such as the milk powder scandal in China and food safety following the Fukushima nuclear accident and tsunami in Japan. This book will be an important resource for scholars, academics and policy-makers in the fields of sociology, economics, food studies, Chinese studies and Japanese studies and theories of risks and safety.

Biotechnology' - the integrated use of biochemistry, microbiology, and chemical engineering for the technological application of the capabilities of microbes and cultured tissue cells - is quickly becoming pervasive and challenging, rapidly developing both new techniques and industries. The Economic and Social Dynamics of Biotechnology - a joint project between Statistics Canada, the Program of Research on Innovation, Management and Economy (PRIME) at the University of Ottawa, and CIRANO at the University of Quebec in Montreal - brings together economic, social, and statistical views on the dynamics of this set of emerging technologies. It examines the costs as well as the benefits - the challenges as well as the choices - of the rapidly expanding science-based world of biodiversity, biopharmaceuticals, and bioinformatics, and it provides suggestions for future work and research. This project fits into an ongoing research program at Statistics Canada to develop meaningful indicators for science, technology, and innovation in a technology-intensive economy. This book tells the story of the inner workings of innovation systems, technological systems, and competence blocs in the production, use, and diffusion of knowledge.

Video recording has recently become an important phenomenon. Although the majority of American homes have at least one video recording set, not much is known about video recording's past and about its continual effect on affiliated industries. This text documents the history of magnetic recording, stressing its importance in consumer as well as commercial applications from the advent of magnetism through the invention of such new technologies as Digital Audio Tape (DAT), High Definition Television (HDTV), and a multitude of sophisicated Digital Video Cassette Recorders.

The Soviet Air Force had just started to re-equip with modern fighters when the Germans opened Operation Barbarossa, the invasion of the Soviet Union. Hundreds of fighters were destroyed in the first few days, but many of these were obsolete biplanes and monoplanes. The remaining fighters, including more modern types such as the MiG-3 and LaGG-3, tried to stem the Nazi advance. This book details the development of the Red Air Force fighters, from the dark days of Operation Barbarossa, to eventual triumph over the ruins of Berlin. Starting with obsolete aircraft such as the Polikarpov biplane and monoplane fighters, the Soviets then settled on two main lines of development; the inline-engined LaGG-3 and its radial-engined derivatives, the La-5 and La-7, and the inline-engined Yakovlev fighters, which were produced in greater numbers than any other series of fighters. Not only are these aircraft described in great detail, but experimental fighters are also dealt with. In addition to the descriptions, accurate colour profiles are provided illustrating the evolution of these aircraft in terms of design, camouflage, and markings. From the fixed undercarriage I-15bis biplane of the beginning of the Great Patriotic War, to the superb La-7 and Yak-3 fighters of the last year of the war, the fighters of the Red Air Force are all covered in this comprehensive book.

Shipbuilding in the United Kingdom provides a systematic historical account of the British Shipbuilders Corporation, first looking at this major industry under private enterprise, then under state control, and finally back in private hands. The chapters trace the evolution of public policy regarding shipbuilding, ship repair, and large marine engine building through the tenures of radically different Labour and Conservative governments, and through the response of the board of the British Shipbuilders Corporation, trade unions, and local management also. The book benefits from comprehensive archival research and interviews from the 1990s with leading players in the industry, as well as politicians, shipbuilders, trade union leaders, and senior civil servants. This authoritative monograph is a valuable resource for advanced students and researchers across the fields of business history, economic history, industrial history, labour history, maritime history, and British history.

Here is a great introduction to the remarkable mind of Shigeo Shingo, indisputably one of the great forces in manufacturing. In this book Dr. Shingo describes his approach to manufacturing improvements, developed and refined over the course of a brilliant career. He called it the Scientific Thinking Mechanism (STM).

"The Sayings of Shigeo Shingo "leads you through the five stages of STM, with appropriate examples taken from notes Dr. Shingo collected during his consulting trips to American and Japanese plants. It shows how, in many cases, the most brilliant ideas are often so simple they're overlooked. Or they're dismissed because they seem ridiculous:

A Japanese plant, after first rejecting the idea as "too silly," finds that unhulled rice is ideal for smoothing the rough surfaces on pressure-formed ebonite switchesGranville-Phillips, in Boulder, Colorado, reduced defects to zero in one process after Dr. Shingo suggested illuminating circuit boards from belowto reduce errors involved in the insertion of diodes and resistors

"The Sayings of Shigeo Shingo" is must reading for plant managers and engineers. It formalizes the powerful and creative way of thinking that Shingo himself used time and again to overcome problems that seemed virtually insurmountable.

Davanti Nella Gara, an Italian bicycle company, makes the best racing bikes in the world. But after decades of market dominance, competitors have brought the industry leader back to the Peloton. The company's second-generation owner longs for retirement, but a tired product lineup is pushing down profits and the firm's market value will never support his ride into the sunset. The flawed but beloved owner seeks out the counsel of an old friend and successful businessman, who steers him toward a fast and remarkable transformation, one fueled by a relentless focus on innovation excellence. An engaging business novel, Winning Innovation dives into the art and science of innovation; the thrills of the European bike-racing circuit; the vibrant landscape and cuisine of Italy; and a cast of intriguing characters who work to put Davanti on the road to sustained prosperity. The company's leader isn't afraid to learn and apply new ideas to reenergize his company, and finds he cares more about his employees than he could ever imagine. A young innovator struggles to see a product idea to fruition as well as rise into management - and he falls in love along the way. A newly promoted R&D director brings teamwork and transparency to product development and aligns the entire company around innovation. With the help of a seasoned and persistent change agent, in just a year, Davanti deploys a well-defined and -sequenced transformation - a complete and seamless process that can be replicated and scaled by most companies. The leader engages associates in pursuit of the right vision and strategy, candidly supporting them all as they unleash their creative sparks, work through personality conflicts, and take on real-world challenges faced by companies every day. They learn and apply traditional R&D principles in new ways (e.g., cost of delay, sprints, fail fast, late start) and successfully leverage emerging innovation and change-management principles (e.g., idea-creation events, knowledge management, workplace humility, visual management, lean project management). And an aligned, three-phase innovation process - from idea creation to technology development and product design - provides the innovation infrastructure the company needs for revenue creation and success beyond racing bikes. From a top-heavy organization dominated by power struggles and finger-pointing emerges a new Davanti Nella Gara - a flattened, innovative company with: Clear vision and endorsed goals and strategy Speed, responsiveness, and agility Widespread, successful creativity Collaboration and teamwork Superior risk management Respect for people Unquestionable ethics Changed leadership and associate behaviors Project management excellence Rapid problem-solving and experimentation Not just the story of an R&D transformation, Winning Innovation illustrates a companywide transformation of a magnitude that only superior R&D can make possible. It may well be the first book to chronologically introduce the principles for a complete innovation excellence transformation along with the parallel people transformation that is necessary for real change to occur. The end result for Davanti Nella Gara is a dominant new culture based on respect and humility, highly efficient processes that will deliver a wealth of innovations, sales, and profits for many years to come, and an owner who leaves a bright future for the people and company he's known and loved his entire life.

The new millennium has carried several challenges for patent law. This up-to-date book provides readers with an important overview of the most critical issues patent law is still facing today at the beginning of the twenty first century, on both sides of the Atlantic. New technological sectors have emerged, each one with its own features with regard to innovation process and pace. From the most controversial cases in biotech to the most recent decisions in the field of software and business methods patent, patent law has tried to stretch its boundaries in a way to accommodate such new and controversial subject matters into its realm. Biotechnology and Software Patent Law will strongly appeal to postgraduate students specializing in IP law, international law, commercial and business law, competition law as well as IP scholars, academics and lawyers. Contributors: S.D. Anderman, R.B. Bakels, S.J.R. Bostyn, D.L. Burk, V. Di Cataldo, V. Falce, C. Geiger, R.M. Hilty, C.M. Holman, M.A. Lemley, A. Ottolia, J. Pila, J.R. Thomas, P.L.C. Torremans

This book adopts a case study based research approach to examine the contemporary issues in the fashion industry. It documents real-world practices in fashion business from production, marketing to operations. Founded on an extensive review of literature, these case studies discuss the challenges that are pertinent to the current business environment in this important industry, provide benchmarks and generate insights to practitioners as well as suggest future directions to researchers. The book serves as a nexus of the theories and the industrial practices that advances knowledge for both the academia and the private sector in fashion business.