Irina Goryacheva authors this volume titled Rapid Immunotests for Clinical, Food and Environmental Applications that is devoted to the latest research in the area of the construction and application of rapid immunotests with plasmonic and luminescent detection, with special attention paid to the achievements of nanotechnology in the areas of labels and solid supports creation.With close attention to the basic principles and the specific issues, considering the breadth of the field that the rapid tests may offer, the coverage of this book is by no means complete, keeping open space for challenge and research

Endothelium, the new volume in the Advances in Pharmacology series, presents readers with a variety of chapters that cover various endothelium-derived mediators and their changes with gender, and during vascular development, senescence, and hypertensive disorders. Topics include endothelium, nitric oxide, gap junctions, potassium channels, endothelin, vascular development, vascular permeability, gender, aging, and preeclampsia. With contributions from the best authors in the field, the volume is an essential resource for pharmacologists, immunologists, and biochemists alike.

Performance Testing of Textiles: Methods, Technology and Applications examines the developed and established methodology for testing performance textiles, also summarizing the material properties for advanced applications. This book emphasizes reproducible tests using commonly used experimental methods reported in scientific literature and internationally recognized testing standards to quantify textile material properties and performance. After an introductory explanation of key fiber and textile properties and testing methods, the book summarizes electronic testing theories, technologies, and instrumentation for performance textiles. Also covered are aspects of military textile, medical textile, sportswear, smart composites, and wearable textiles which, as examples, present the latest research and results related to performance textile testing and applications.

Advances in Technical Nonwovens presents the latest information on the nonwovens industry, a dynamic and fast-growing industry with recent technological innovations that are leading to the development of novel end-use applications. The book reviews key developments in technical nonwoven manufacturing, specialist materials, and applications, with Part One covering important developments in materials and manufacturing technologies, including chapters devoted to fibers for technical nonwovens, the use of green recycled and biopolymer materials, and the application of nanofibres. The testing of nonwoven properties and the specialist area of composite nonwovens are also reviewed, with Part Two offering a detailed and wide-ranging overview of the many applications of technical nonwovens that includes chapters on automotive textiles, filtration, energy applications, geo- and agrotextiles, construction, furnishing, packaging and medical and hygiene products.

Developing an ISO 13485-Certified Quality Management System: An Implementation Guide for the Medical-Device Industry details the lessons learned from a real-world project focusing on building an ISO 13485:2016 Quality Management System (QMS) from scratch and then having it officially certified. It is a practical guide to building or improving your existing QMS with tried and tested solutions. The book takes a hands-on approach-first teaching the top 25 lessons to know before starting to develop a QMS and then walking you through the process of writing the quality manual and the standard operating procedures, training the staff on the QMS, organizing an internal audit, executing a management review, and finally passing the necessary external audits and obtaining certification. It helps you to progress from one task to the next and provides all the essential information to accomplish each task as quickly and efficiently as possible. It does not attempt to replicate the standard but instead drills into the standard to expose the core of each section of the standard and reorganize its contents into a practical workflow for developing, maintaining, and improving a Lean QMS. The book includes a wealth of real-world experience both from the author's personal dive into quality management, and from the experiences of other companies in the field and provides handy checklists for ensuring key documents and processes are fit for use-the emphasis here is to help ensure you have considered all relevant aspects. In addition, the book is not intended as a "cheat sheet" for the standard or as a review of the standard that only adds lengthy commentary on each of the clauses. Instead, the book fixes easy misunderstandings regarding QMS, provides insight into why the various clauses are written the way they are, and provides a great base to both understanding ISO 13485 QMS and developing your own QMS. The book is intended to serve both experts and novices audiences-it provides special insight on the most crucial and effective aspects of QMS.

This new volume provides important information on potential applications and new developments in functional health foods and nutraceuticals. It looks at the health-promoting properties in functional foods and beverages as well as nutraceuticals. Some health issues that are considered in conjunction with these foods and nutraceuticals include oxidative stress, obesity, pharyngitis, low cognitive concentration, among others. Research topics include the antioxidant properties of certain products, the development of functional and medicinal beverages, nutraceuticals and functional foods for alternative therapies, and more.

Developing Food Products for Customers with Specific Dietary Needs explains the process for developing foods for customers who have specific dietary needs, further shining a light on the number of increasing medical conditions related to food intake that have emerged in the past few decades. From increased fat and sugar intake leading to higher levels of obesity, to greater levels of coeliac disease, the ingredients and nutritional content of food is becoming more and more important. Additionally, consumers are following particular diets for many different reasons, be it health related, or for religious or moral reasons. The first part of the book looks, in detail, at the organizational structure required within a company to allow for the development of food products which meet the needs of these customers, while the second part presents a number of case studies highlighting the development of food products for various dietary requirements. Precise coverage includes section on the development of low-sodium, low-sugar, low-fat, and low-carbohydrate products with the aim of producing healthier foods, as well as the development of organic and vegetarian products for consumers who are following diets for personal reasons. The potential solutions for developing foods for customers who have specific dietary needs are likely to include both ingredients and technology developments. The ingredients area includes simple reductions as well as replacement strategies, whilst technology will be applied to both the ingredient itself and the host food product. All are aimed at maintaining the product quality as perceived by the customer.

Davanti Nella Gara, an Italian bicycle company, makes the best racing bikes in the world. But after decades of market dominance, competitors have brought the industry leader back to the Peloton. The company's second-generation owner longs for retirement, but a tired product lineup is pushing down profits and the firm's market value will never support his ride into the sunset. The flawed but beloved owner seeks out the counsel of an old friend and successful businessman, who steers him toward a fast and remarkable transformation, one fueled by a relentless focus on innovation excellence. An engaging business novel, Winning Innovation dives into the art and science of innovation; the thrills of the European bike-racing circuit; the vibrant landscape and cuisine of Italy; and a cast of intriguing characters who work to put Davanti on the road to sustained prosperity. The company's leader isn't afraid to learn and apply new ideas to reenergize his company, and finds he cares more about his employees than he could ever imagine. A young innovator struggles to see a product idea to fruition as well as rise into management - and he falls in love along the way. A newly promoted R&D director brings teamwork and transparency to product development and aligns the entire company around innovation. With the help of a seasoned and persistent change agent, in just a year, Davanti deploys a well-defined and -sequenced transformation - a complete and seamless process that can be replicated and scaled by most companies. The leader engages associates in pursuit of the right vision and strategy, candidly supporting them all as they unleash their creative sparks, work through personality conflicts, and take on real-world challenges faced by companies every day. They learn and apply traditional R&D principles in new ways (e.g., cost of delay, sprints, fail fast, late start) and successfully leverage emerging innovation and change-management principles (e.g., idea-creation events, knowledge management, workplace humility, visual management, lean project management). And an aligned, three-phase innovation process - from idea creation to technology development and product design - provides the innovation infrastructure the company needs for revenue creation and success beyond racing bikes. From a top-heavy organization dominated by power struggles and finger-pointing emerges a new Davanti Nella Gara - a flattened, innovative company with: Clear vision and endorsed goals and strategy Speed, responsiveness, and agility Widespread, successful creativity Collaboration and teamwork Superior risk management Respect for people Unquestionable ethics Changed leadership and associate behaviors Project management excellence Rapid problem-solving and experimentation Not just the story of an R&D transformation, Winning Innovation illustrates a companywide transformation of a magnitude that only superior R&D can make possible. It may well be the first book to chronologically introduce the principles for a complete innovation excellence transformation along with the parallel people transformation that is necessary for real change to occur. The end result for Davanti Nella Gara is a dominant new culture based on respect and humility, highly efficient processes that will deliver a wealth of innovations, sales, and profits for many years to come, and an owner who leaves a bright future for the people and company he's known and loved his entire life.

General Motors (GM)'s attempt to adapt the renowned Toyota production system for its own automotive manufacturing plants had historically produced disappointing results. Why was it not sufficiently successful? This book aims to shed insights into GM's failed attempt through the analysis of work organization reforms and labor-management relations on production-system efficiency. The book examines collective bargaining agreements between automakers and the United Auto Workers union and the arbitration rulings in retrospect to illuminate the critical role continuous improvement activities initiated by production workers would play in enhancing performance management. It also looks at the impact of the meritocratic system in Japanese auto plants on performance success. As GM begins operations at its new electric vehicle assembly plant, Factory Zero, the book analyses the challenges of such production for both employment relations and workforce deployment. The book will be a useful reference for those interested in a comparative study of management styles and a better understanding of Japanese manufacturing practices.

Clothing for Children and Teenagers: Anthropometry, Sizing and Fit addresses the complexities of developing size specifications for clothing aimed at seven to seventeen year olds. Children and teenagers experience rapid physical growth and alterations in body shape as they develop-changes that pose significant challenges in creating apparel sizing systems. The book begins by introducing the principles of apparel fit and sizing systems. Drawing on the author's own fieldwork, it goes on to discuss methods of conducting anthropometric surveys in children and teenagers, and techniques for analyzing the resulting data in order to produce successful sizing systems.

This first of this set of books presents the various sustainable approaches in terms of circular economy and micro plastic pollution pertaining to the textiles and fashion supply chain. Sustainability is one of the important aspects in today's industrial context, which is followed by every industrial sector with no exception to textiles and fashion. Sustainability and strict adherence to the principles of sustainability has become one of the essential needs in industry. There are countless measures in terms of various approaches to make the textiles and fashion sector sustainable. These measures, but not limited to, range from innovating and implementing new fibres and raw materials, introducing innovative manufacturing methods, chemicals, processes to focus on all the possible stages of a textile product's life cycle from cradle to grave. These approaches include making the textiles and fashion sector circular and also development of new products from sustainable raw materials/processes or combination of both.

Advances in Women's Intimate Apparel Technology discusses the design and manufacture of intimate apparel and how the industry is increasingly embracing novel materials, new technologies, and innovations in sizing and fit. The book reviews the ways in which new materials and methods are improving the range, function, and quality of intimate apparel, with particular focus on brassiere design. Part One introduces the advanced materials used for intimate apparel, including novel fabrics and dyes and finishes, along with materials for wiring and embellishments. Part Two discusses the role of seamless technology in intimate apparel production, covering lamination, moulding, and seamless knitting. Finally, Part Three reviews advances in design, fit, and performance.

Information Systems for the Fashion and Apparel Industry brings together trends and developments in fashion information systems, industrial case-studies, and insights from an international team of authors. The fashion and apparel industry is fast-growing and highly influential. Computerized information systems are essential to support fashion business operations and recent developments in social media, mobile commerce models, radio frequency identification (RFID) technologies, and ERP systems are all driving innovative business measures in the industry. After an introductory chapter outlining key decision points and information requirements in fast fashion supply chains, Part One focuses on the principles of fashion information systems, with chapters covering how decision making in the apparel supply chains can be improved through the use of fuzzy logic, RFID technologies, evolutionary optimization techniques, and artificial neural networks. Part Two then reviews the range of applications for information systems in the fashion and apparel industry to improve customer choice, aid design, implement intelligent forecasting and procurement systems, and manage inventory and returns.

Not long ago, American manufacturing was in sharp decline. The Big Three carmakers closed dozens of plants, mostly in Michigan and other surrounding states, eliminating more than 250,000 jobs. Another quarter of a million workers lost their jobs in related industries. Now United States manufacturing is making a comeback--thanks, in part, to the transplanting of Japanese corporations of over 25 billion dollars worth of heavy industry and 100,000 jobs. The Japanese companies are making long-term commitments where United States business leaders had seemed to give up hope. The success of these ventures is the result of the sweeping revolution in the organization of technology, work, and production that lies at the heart of the Japanese model of production. This book explores the rise of this Japanese model and provides a detailed examination of the processes which have brought about its transfer to the United States. It presents new and original data on the extent of Japanese investment in both United States heavy industry and high technology and provides an empirically-grounded discussion of the reasons why this has occurred. The authors focus on the transfer of basic elements of Japanese production organization and develop a broad conceptual theme contrasting the Japanese model of production organization with that of United States Fordism. With a wealth of illustrations and straightforward examples, this work will appeal to those interested in urban and regional economics, industrial organization, labor relations, and economic geography.

1.Provides detailed information about two healthy substitutes for cereal crops 2.Explains the importance of utilizing ancient crops as new era Superfoods 3.Promotes the concept of utilizing food crops as nutraceuticals by discussing physical, chemical and physiological characteristics of Chia and Quinoa 4.Describes the importance of using Chia and Quinoa to help as functional foods

Biomass Supply Chains for Bioenergy and Biorefining highlights the emergence of energy generation through the use of biomass and the ways it is becoming more widely used. The supply chains that produce the feedstocks, harvest, transport, store, and prepare them for combustion or refinement into other forms of fuel are long and complex, often differing from feedstock to feedstock. Biomass Supply Chains for Bioenergy and Biorefining considers every aspect of these supply chains, including their design, management, socioeconomic, and environmental impacts. The first part of the book introduces supply chains, biomass feedstocks, and their analysis, while the second part looks at the harvesting, handling, storage, and transportation of biomass. The third part studies the modeling of supply chains and their management, with the final section discussing, in minute detail, the supply chains involved in the production and usage of individual feedstocks, such as wood and sugar starches, oil crops, industrial biomass wastes, and municipal sewage stocks.

Manufacturing and Novel Applications of Multilayer Polymer Films discusses the advancements in multilayer technology, including its capability to produce hundreds of layers in a single film by a melt coextrusion process. These engineered films can have significantly enhanced performance properties, allowing films to be made thinner, stronger, and with better sealing properties. As recent developments in feedblocks and materials have opened up a range of new possibilities, this book discusses different feedblocks, and viscosity and material considerations. It is the first comprehensive summary of the latest technology in multilayer film processing and related applications, and is written from a practical perspective, translating research into commercial production and real world products. The book provides fundamental knowledge on microlayer coextrusion processing technology, how to fabricate such structures, structure and properties of such microlayers, and potential applications, thus helping research scientists and engineers develop products which not only fulfill their primary function, but can also be manufactured reliably, safely, and economically.

Offers a new perspective on "traditional" Asian medicines Provides original insights into "traditional" Asian pharmaceutical industries Broad-ranging, multidisciplinary and comparative research on Asian medicine in China, India, Japan, Mongolia, and Nepal Relevant to scholars, students, health professionals, and policy makers Includes extensive bibliographies of essential but little-known scholarship on Asian medicines from Asia

This book provides a wealth of information and a critically required framework for sustainable automobile policy development in major Asian countries. It also gives wide-ranging policy options, ranging from technological to institutional solutions to automobile emission problems, based on empirical case studies and comparative policy and regulatory analysis. It is a useful reference with valuable insights on how rapidly changing economies are adopting their policy and regulatory structures to cope with the progressively severe environmental impacts of automobile increase.

This book contains the most current information on how to implement, develop and maintain an effective Corrective Action and Preventive Action (CAPA) and investigation program using a 9-step closed-loop process approach for medical device, pharmaceutical and biologic manufacturers, as well as any company or institution, which has to maintain a quality system. CAPA violations along with ineffective complaint investigations continue to be the number one cited violation of device warning letters for the past four years, leading the US Food and Drug Administration or FDA to remind firms to fully investigate complaints, find the root cause of nonconforming products and document their CAPA activities. A review of FDA warning letters issued to pharmaceutical companies reveals that most of these warning letters resulted from recurring failures, ineffective investigations found, and missing or inappropriate corrective and preventive actions. Companies often make the mistake of fixing problems in their processes by revising procedures or more commonly by 'retraining' employees that may or may not have caused the problem. This is typically event-focused. Companies then will make the false assumption that the errors have been eradicated. In many cases they will also consider the steps taken as their Preventive Action. The reality is that the causes of the failure were never actually determined; therefore the same problem will recur over and over. CAPA is a complete system that collects information regarding existing and potential quality problems. It analyzes and investigates the issues to identify the root cause of nonconformities. CAPA is not just a quick-fix, simple approach. It is a process and has to be understood throughout organizations. This book addresses all of the above issues, in a pragmatic, down- to-earth manner.

Using real cases of food fi rms and agriculture supply chains as a context, How is Digitalization Affecting Agri-food? New Business Models, Strategies and Organizational Forms aims to understand the key themes in strategic and organizational research in this area. Despite the importance of food and agriculture in the current political and societal context, analysis of the impact of digitalization and information technologies on the industry is still limited. The objective of this monograph is to understand the direction of this change. With case studies of food firms and agriculture supply chains it sets out to conceptualize food organizing and organizations as a fruitful object of inquiry, both at the intra and interorganizational levels. It aims to understand new business models, strategies, and organizational forms. Contributions in this stream of research have the potential to yield important and relevant insights for both scholars and societies. This book is written primarily for academics engaged in innovation management or strategy, or conducting organizational behavior research. It will also be of relevance to practitioners and managers in the agri-food industry.

The Life-Cycle of Pharmaceuticals in the Environment identifies pathways of entry of pharmaceuticals into the environment, beginning with the role of global prescribing and disposal practices. The book then discusses typical levels of common pharmaceuticals and how they can be determined in natural waters such as raw and treated sewage, and in potable water. In addition, sections examine methods currently available to degrade pharmaceuticals in natural waters and some of their ecotoxicological impacts, along with future considerations and the growing concept of product stewardship.

This volume explains cleaning of cotton after blow room treatment and individualization process in conventional card including functions related to licker-in, cylinder, and doffer, and so forth. Description of modern card includes improved cleaning at higher production rates and individualization at such higher rates. Larger part of the book is devoted to drawing of the sliver and relative description for any modern machine including on-line controls and introduction of indicator lamp system to improve both machine and labour efficiency is discussed as well. This volume also includes the related calculation for both card and draw frame. Focuses on modern carding processes, functions, and attachments. Includes chapters on defects in carding and drawn material and related calculations. Highlights the features of modern draw frame, especially the drafting system. Discusses automation and processes of modern carding machines for improving machine efficiency. Describes drafting and doubling including drafting as basic processes of spinning. This volume is aimed at senior undergraduate/Graduate students in Textile Engineering, staple fibre processing, spinning of staple fibres.

First published in 1976, Industrial Location and Planning in the United Kingdom investigates in detail the nature of the changes taking place in the location of manufacturing industry since the 1950s and the reasons for them, including the effects of government regional policy and of factors such as market accessibility, labour availability and cost, transport facilities and personal residential preferences by industrialists and workers. The book brings together a wide range of published and unpublished material in discussing and evaluating explanations for regional and local manufacturing growth or decline. Government regional policy and planning is singled out for special attention, in terms of the impact of Development Area grants, of local planning controls, and of the town programmes. Manufacturing movement to new locations and the implications of government regional policies for industrial efficiency are examined in detail, together with the reasons for locational change in key but controversial industries such as steel, motor vehicles and electronics. This book will be of interest to students of urban planning, manufacturing, and development as well as city planners.

This book provides an understanding of innovation models and why they are important in the business context, and considers sources of innovation and how to apply business frameworks using real-world examples of innovation-led businesses. After providing a solid background to the key concepts related to innovation models, the book looks at why innovation takes place and where the sources of innovation lie, from corporate research to crowd-sourced and government-funded initiatives. Innovation models across manufacturing, services and government are explored, as well as measuring innovation, and the impact of design thinking and lean enterprise principles on innovation and sustainability-driven imperatives. Offering a truly comprehensive and global approach, Business Innovation should be core or recommended reading for advanced undergraduate, postgraduate, MBA and Executive Education students studying Innovation Management, Strategic Management and Entrepreneurship.