Provides the latest information on trends in this fast-growing market Focuses on the six marine taxa that offer the most exciting potential Gives practical guidance to anyone wishing to enter this sector

The contemporary opioid crisis is widely seen as new and unprecedented. Not so. It is merely the latest in a long series of drug crises stretching back over a century. In White Market Drugs, David Herzberg explores these crises and the drugs that fueled them, from Bayer's Heroin to Purdue's OxyContin and all the drugs in between: barbiturate "goof balls," amphetamine "thrill pills," the "love drug" Quaalude, and more. As Herzberg argues, the vast majority of American experiences with drugs and addiction have taken place within what he calls "white markets," where the prescription of addictive drugs is legal and medically approved. These markets are widely acknowledged but no one has explained how they became so central to the medical system in a nation famous for its "drug wars"--until now. Drawing from federal, state, industry, and medical archives alongside a wealth of published sources, Herzberg re-connects America's divided drug history, telling the whole story for the first time. He reveals that the driving question for policymakers has never been how to prohibit the use of addictive drugs, but how to ensure their availability in medical contexts, where profitability often outweighs public safety. Access to white markets was thus a double-edged sword for socially privileged consumers, even as communities of color faced exclusion and punitive drug prohibition. To counter this no-win setup, Herzberg advocates for a consumer protection approach that robustly regulates all drug markets while caring for people with addiction by ensuring them safe, reliable access to medication-assisted treatment. Accomplishing this requires rethinking a drug/medicine divide born a century ago that, unlike most policies of that racially segregated era, has somehow survived relatively unscathed into the twenty-first century. By showing how the twenty-first-century opioid crisis is only the most recent in a long history of similar crises of addiction to pharmaceuticals, Herzberg forces us to rethink our most basic ideas about drug policy and addiction itself--ideas that have been failing us catastrophically for over a century.

Presents exclusive material on integration of 4D imaging and 4D printing Demonstrates the industrial applications of 4D imaging in 4D printing using multiple case studies Discusses use of open source 4D imaging tools for biomedical applications Includes in-house development of smart materials for 4D printing Reviews low cost, indigenous lab scale solutions for various veterinary applications

This title was first published in 2001. The emergence and development of automobile production in Australia was a long, drawn out and costly business for car buyers and taxpayers. Wheels and Deals, is the story of some of the causes and effects of Australian Government policies on the local development of one of the most significant industries of the 20th century.

This study of Ferranti in its last six years of a long history provides a detailed exposition of the British and American businessmen who combined to terminate one of the UK's leading defence electronics firms. Involving action in the Middle East, South Africa and Pakistan, as well as the UK and USA, this highlights the precarious nature of international arms trading.

This book examines the impact of economic reforms in India on the pharmaceutical industry and access to medicines. It traces the changing production and trade pattern of the industry, research and development (R&D) preferences and strategies of Indian pharmaceutical firms, patent system alongside pricing policy measures and their shortcomings. It also analyses the public health financing system in India driven largely by out-of-pocket expenditure - about 60 per cent - and characterised by very high share of medicines in total health expenditure.

The subject of this book is applied Bayesian methods for chemistry, manufacturing, and control (CMC) studies in the biopharmaceutical industry. The book has multiple authors from industry and academia, each contributing a case study (chapter). The collection of case studies covers a broad array of CMC topics, including stability analysis, analytical method development, specification setting, process development and optimization, process control, experimental design, dissolution testing, and comparability studies. The analysis of each case study includes a presentation of code and reproducible output. This book is written with an academic level aimed at practicing nonclinical biostatisticians, most of whom have graduate degrees in statistics. * First book of its kind focusing strictly on CMC Bayesian case studies * Case studies with code and output * Representation from several companies across the industry as well as academia * Authors are leading and well-known Bayesian statisticians in the CMC field * Accompanying website with code for reproducibility * Reflective of real-life industry applications/problems

Consolidation activities such as mergers and acquisitions (M&As) have been one of the major strategies adopted by Indian firms to withstand global competition. M&As experienced a substantial increase in value and volume during the post-liberalization era, facilitated by the presence of foreign subsidiaries in the Indian market as well as competitive pressure on domestic firms. The increased foreign investment through M&As brought new dimensions to the fore such as the implications on technological performance, efficiency, and more importantly, competition in the Indian market. The Globalisation of Indian Business: Cross Border Mergers and Acquisitions in Indian Manufacturing provides an in-depth analysis of these issues, specifically aiming to understand whether the M&As strategies helped the firms to achieve their desired objectives in terms of improvement in technology, efficiency and market power in the context of the increase of M&As in India, using appropriate statistical and econometric techniques. The book is of additional importance in the context of the recently implemented Competition Act, replacing the thirty year old MRTP Act in India. The new Act aims to maintain competition and protect consumers' interests without harming that of the producers'. Based on the analysis, broadly, the study cautions the regulators to rethink the efficiency defence argument and become more vigilant on the creation of monopolies. On the other side, it suggests firms should reconsider their post-merger integration strategy since consolidation has not led to a sustainable increase in market share of the surviving firms.

Against the backdrop of growing anti-globalisation sentiments and increasing fragmentation of the production process across countries, this book addresses how the Indonesian economy should respond and how Indonesia should shape its trade and industrial policies in this new world trade environment. The book introduces evaluation not on tariffs but on new trade instruments such as non-tariff measures (SPS, TBT, export measures and beyond border measures), and looks at industrial policies from a broader perspective such as investment, accessing inputs, labour, services, research and innovation policies. "The Open Access version of this book, available at http://www.taylorfrancis.com/books/10.4324/9781315161976, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license."

Policy analysis is a dynamic process of discovery rather than a passive exercise of memorizing facts and conclusions. This text provides opportunities to "practice the craft" of policy analysis by engaging the reader in realistic case studies and problem-solving scenarios that require the selection and use of applicable investigative techniques. US Agricultural and Food Policies will assist undergraduate students to learn how policy choices impact the overall performance of agricultural and food markets. It encourages students to systematically investigate scenarios with appropriate positive and normative tools. The book emphasizes the importance of employing critical thinking skills to address the complexities associated with the design and implementation of twenty-first-century agricultural and food policies. Students are asked to suspend their personal opinions and emotions, and instead apply research methods that require the careful consideration of both facts and values. The opportunities to build these investigative skills are abundant when we consider the diversity of modern agricultural and food policy concerns. Featuring case studies and critical thinking exercises throughout and supported by a Companion Website with slides, a test bank, glossary, and web/video links, this is the ideal textbook for any agricultural policy class.

Pharmaceuticals play a central role in health care throughout the world. The pharmaceutical industry is beset with difficulties as increasing research and development expenditure yields fewer new treatments. Public and private budgets strain under the weight of high prices and limited access. The world's poor see little effort to address diseases prevalent in less affluent societies, while the world's wealthy are overusing prescription drugs, risking their health and wasting resources. The debate over health care reform and the ongoing global economic crisis form the backdrop for this extraordinarily timely examination of the global system for the development, production, distribution and use of medicines. The authors are acknowledged experts in the fields of pharmaceutical law and policy, with many years experience advising governments, multilateral organizations and policy-makers on issues involving innovation, access and use of medicines. Supported by a team of independent scientists, doctors and lawyers, they take an insightful look at the issues surrounding global regulation of the pharmaceutical sector, and offer pragmatic suggestions for reform. This book will be of interest to government policy-makers, members of industry, healthcare professionals, teachers, students and lawyers in the fields of public health, intellectual property and international trade.

Provides a detailed overview discussion on different classes of plant origin natural toxins in food. Explain how IR, NMR, and mass spectrometry are utilized in its characterization and identification. Describes applicability of HPLC, LC-MS, GC-MS, and HPTLC techniques for its detection and quantification Discusses progress of the field in utility of capillary electrophoresis, ELISA, and biosensors for quantitative application of the technique.

This book presents decision support tools that can be used in the early design stage to analyze the feasibility of a product and its components for remanufacturing. It also covers how to design a product specifically for remanufacturing and offers supporting case studies. This is a comprehensive solutions guide for remanufacturing decision-making. The book illustrates an approach that can be used at the product End-of-Life (EOL) stage to generate optimized recovery plans for the returned products. Opportunities for Industry 4.0 to support remanufacturing along with case studies are included to showcase the decision-making tools. Remanufacturing and Remanufacturability Assessment for the Circular Economy: A Solutions Guide will be of interest to practitioners, business professionals, and researchers that work in the industrial and manufacturing sectors. Those involved with supply chain management and advanced technologies associated with Industry 4.0, sustainability, and integrated techniques of circular supply chains will also find this book very useful.

Materials and Technology for Sportswear and Performance Apparel takes a close look at the design and development of functional apparel designed for high-performance sportswear. Implementing materials, performance, technology, and design and marketing, the book examines this rapidly emerging textile market and outlines future directions and growing trends. The book begins by explaining how a comfort-driven focus has led the industry to embrace knitted fabric as a popular choice of constructional material. Using examples of leading brands, it outlines the basic terminology, structural details, and essential properties appropriate for performance apparel, especially for sportswear. This book describes the differences between woven and knitted structures, provides an understanding of fabric behavior and the characteristics of a functional garment, and outlines the importance of garment fit and consumer perception of garment comfort in its design and development. The authors present key research outcomes on the design and development of functional apparel designed for high-performance sportswear that explore smart materials, impact-resistant fabrics and pressure sensing. They consider the use of 3-D body scanning and its influence on pattern engineering for apparel product development; highlight the widely used fiber types for sportswear and the importance of fiber blends and their performance, and discuss the relevance of fabric structure and its interaction with the human body. The book also presents research on moisture management and temperature regulation and analyzes the performance and development of smart sportswear intended for monitoring health and performance for a range of end uses. A definitive guide detailing the future of functional clothing and sportswear, this book: Describes how to design and develop functional clothing for sportswear Reflects current research outcomes and industry requirements Clarifies with visual illustration, practical examples, and case studies an understanding of techniques and concepts Explores specifics of garment design such as fit, shape, function, fashion and design Focuses on a commitment to designing ethical and sustainable products

This brand new textbook by one of the leading engineering authors covers basic sheet-metal fabrication and welding engineering principles and applications in one volume - an unrivalled comprehensive coverage that reflects current working and teaching practice. It is fully up-to-date with the latest technical information and best practice and also includes chapters on non-technical but equally essential subjects such as health and safety, personal development and communication of technical information.Roger Timings covers these areas of mechanical engineering and workshop practice in a highly practical and accessible style. Hundreds of illustrations demonstrate the practical application of the procedures described. The text includes worked examples for calculations and key points to aid revision. Each chapter starts with learning outcome summaries and ends with exercises which can be set as assignemnts.The coverage is based on the SEMTA National Occupational Standards which makes this book applicable to a wide range of courses and ensures it also acts as a vital ongoing reference source in day-to-day working practice. All students, trainees and apprentices at up to and including Level 3 will find this book essential reading, particularly those taking:Level 2 NVQs in Performing Engineering OperationsLevel 2 and 3 NVQs in Fabrication and Welding EngineeringLevel 2 NVQs in Mechanical Manufacturing EngineeringC&G 2800 Certificate and Level 3 Diplomas in Engineering and TechnologySEMTA Apprenticeships in Engineering

Globally, nearly 70 billion animals are farmed annually for meat, milk and eggs. Two-thirds of these are farmed intensively. The views held by food companies on animal stewardship, and the management practices and processes that they adopt are, therefore, of critical importance in determining the welfare of these animals. Yet, despite the scale of the food industry's impact, farm animal welfare remains a relatively immature management issue. There is a lack of consensus around the specific responsibilities companies have for farm animal welfare, and around how companies should treat the animals in their or in their suppliers' care. This book, The Business of Farm Animal Welfare, provides an extensive, authoritative analysis of current corporate practice on farm animal welfare. It critically reviews and assesses the ethical and business case for action. Through a series of practitioner case-studies, it describes how companies have addressed farm animal welfare in their operations and supply chains. It analyses the key barriers to companies adopting higher standards of farm animal welfare, and offers a series of practical recommendations to companies, consumers and policy makers on the role that they might play in raising farm animal welfare standards across the food industry. As the first comprehensive account of business and farm animal welfare, this book is an essential resource for researchers, practitioners and general readers looking to understand and influence corporate practice on farm animal welfare.

Strictly off limits to the public, Plum Island is home to virginal beaches, cliffs, forests, ponds -- and the deadliest germs that have ever roamed the planet. "Lab 257" blows the lid off the stunning true nature and checkered history of Plum Island. It shows that the seemingly bucolic island in the shadow of New York City is a ticking biological time bomb that none of us can safely ignore.

Based on declassified government documents, in-depth interviews, and access to Plum Island itself, this is an eye-opening, suspenseful account of a federal government germ laboratory gone terribly wrong. For the first time, "Lab 257" takes you deep inside this secret world and presents startling revelations on virus outbreaks, biological meltdowns, infected workers, the periodic flushing of contaminated raw sewage into area waters, and the insidious connections between Plum Island, Lyme disease, and the deadly West Nile virus. The book also probes what's in store for Plum Island's new owner, the Department of Homeland Security, in this age of bioterrorism.

"Lab 257" is a call to action for those concerned with protecting present and future generations from preventable biological catastrophes.

To the surprise of many, regionally embedded clusters of small to medium sized businesses have continued to exist in spite of industrialisation and mass production. While scholars have discovered that the advantages of embeddedness in terms of industrialisation were situated in interfirm cooperation and conflict resolving mechanisms, it is far less clear how changing historical circumstances on the world market, i.e. globalisation, affected such systems. Taking a look inside Leipzig, a capital of the global fur industry between 1870 and 1939 with its numerous highly specialised businesses, both in production as well as trade, World Market Transformation examines the robustness of district firms within the highly volatile international fur business. This book examines how firm embeddedness not only served to overcome challenges related to industrialisation, but also strengthened the abilities of cluster firms to deal with changing world market circumstances. World Market Transformation integrates the "interior-biased" research tradition on local business systems and industrial districts into the "exterior" fields of global and transnational history. It is demonstrated that the local business district not only emerged because of the expansion of international trade, but that district processes of interfirm cooperation also gave shape to the spatial distribution, conventions and structures of the very same world market. The analysis of embedded communities thus offers an important instrument to examine phenomena of economic globalisation, but also how such macro-economic developments have been shaped and actively constructed by local actors.

Appraising cancer as a major medical market in the 2010s, Wall Street investors placed their bets on single-technology treatment facilities costing $100-$300 million each. Critics inside medicine called the widely-publicized proton-center boom "crazy medicine and unsustainable public policy." There was no valid evidence, they claimed, that proton beams were more effective than less costly alternatives. But developers expected insurance to cover their centers' staggeringly high costs and debts. Was speculation like this new to health care? Cancer, Radiation Therapy, and the Market shows how the radiation therapy specialty in the United States (later called radiation oncology) coevolved with its device industry throughout the twentieth-century. Academic engineers and physicians acquired financing to develop increasingly powerful radiation devices, initiated companies to manufacture the devices competitively, and designed hospital and freestanding procedure units to utilize them. In the process, they incorporated market strategies into medical organization and practice. Although palliative benefits and striking tumor reductions fueled hopes of curing cancer, scientific research all too often found serious patient harm and disappointing beneficial impact on cancer survival. This thoroughly documented and provocative inquiry concludes that public health policy needs to re-evaluate market-driven high-tech medicine and build evidence-based health care systems.

This monograph study of Japan's industrial development focuses on the role of entrepreneurship first in adopting more advanced Western technology and then in innovating new technologies and developing human resources according to its changing organizational needs. Unlike previous studies in English, it covers the whole of the period since the Meiji restoration, refusing to divide up the credit for Japanese growth between technological improvements and investments in human and physical capital. The book investigates the interaction between private entrepreneurial activities and public policy, through a general examination of economic and industrial development, a study of the evolution of management systems, and six industrial case studies.

The Munitions Inquiry, often called the Nye Committee after its chairperson, Senator Gerald Nye, critically examined the pre-World War II military-industrial complex of government agencies, corporations, labor unions, and financial institutions. Cold War-era historians typically presented the inquiry as a naive isolationist search for evil arms dealers who caused wars. Going beyond the concept of the Merchants of Death theory and into the social, intellectual, political, and cultural currents of the 1930s, Coulter expands the dimensions of a topic formerly framed within the narrow confines of isolationism and internationalism. In addition, he shows how the committee's 19th-century values and progressive idealism were unsuited to an era dominated by Hitler and Mussolini. In divesting the Munitions Inquiry of its image as an historical oddity, this book recovers a piece of American history that had been a casualty of World War II and the Cold War.

As innovation moves from the lab to the market, a new research phase begins for the entrepreneur: the market research phase. Inspired by a new technology that can change the world, critical questions need to be addressed. Is there a market for my innovation? Who are my clients? What do they need? Is my innovation filling that gap in the market? Who are my competitors? How are they approaching the market? If these questions are unaswered, entrepreneurs meet potential investors or partners with only a basic understanding of their market. The objective of this book is to fill this gap. It is a practical manual that gives entrepreneurs real-world advice and tools to build a solid market model. The book provides tips, models and tools entrepreneurs can use to collect, interpret and present their market and integrate it into their business plan. What the entrepreneur learns in this book will help him throughout his journey. After going over the market research process, he will learn how to design and use a number of market research tools, and how to adapt them in a life science context. From building a web survey to preparing interviews to doing your own secondary research, this handbook will help him gain a comprehensive understanding of how to perform his own market research activities and how to analyze his data. Finally, a number of frameworks (such as the TAM-SAM-SOM as well as the KANO Model) are described so that he can efficiently share what he has learned, using models that simply yet effectively shares findings.

Surface engineering is considered an important aspect in the reduction of friction and wear. This reference text discusses a wide range of surface engineering technologies along with applications in a comprehensive manner. The book describes various methods in surface engineering technology with a thorough explanation of various aspects of each process that comes under this domain. Apart from an enhanced explanation of the process and its attributes, this book also gives insight into the types of materials, applications, and optimization of surface engineering techniques. It discusses important topics including surface engineering of the functionality of graded materials, materials characterization, processing of biomaterials, design, surface modification technologies and process control, smart manufacturing, artificial intelligence, and machine learning applications. The book: discusses computational and simulation analyses for better selection of process parameters covers optimizations of processes with state-of-the-art technologies discusses applications of surface engineering in medical, agricultural, architecture engineering, and allied sectors covers processing techniques of biomaterials in surface engineering The text is useful for senior undergraduate, graduate students, and academic researchers working in diverse areas such as industrial and production engineering, mechanical engineering, materials science, and manufacturing science. It covers a hybrid process for surface modification, modeling techniques, and issues in surface engineering.

International production networks in manufacturing, particularly in machinery industries, have rapidly developed over the last two decades, resulting in dramatic increases in intra-regional and intra-industry trade, providing a key source of regional growth, integration and development in East Asia. This book provides a better understanding on how to effectively further increase SME participation in East Asian production networks, and in doing so identifies key challenges and issues that they need to address. This book aims to not only fill the theory-practice gap, but also to lay solid foundations for designing national arrangements and a regional institutional frameworks to further encourage and support SME engagement and participation in regional and global production networks. The book contains several country case studies and by drawing upon individual country experiences, at various stages of economic development, this book demonstrates the varying difficulty faced by SMEs in ASEAN member countries attempting to participate in regional production networks and highlighting differences in needs and policy priorities. This book offers both a more focused theme on the assessment of globalization and a rather unique approach by focusing upon the particular importance of SMEs, and by utilizing micro-level data at the firm or plant level. Its policy insights and the richness and uniqueness of the empirical findings will make the book an invaluable contribution to understanding East Asian production networks.

From food punnets to credit cards, plastic facilitates every part of our daily lives. It has become central to processes of contemporary socio-material living. Universalised and abstracted, it is often treated as the passive object of political deliberations, or a problematic material demanding human management. But in what ways might a 'politics of plastics' deal with both its specific manifestation in particular artefacts and events, and its complex dispersed heterogeneity? Accumulation explores the vitality and complexity of plastic. This interdisciplinary collection focuses on how the presence and recalcitrance of plastic reveals the relational exchanges across human and synthetic materialities. It captures multiplicity by engaging with the processual materialities or plasticity of plastic. Through a series of themed essays on plastic materialities, plastic economies, plastic bodies and new articulations of plastic, the editors and chapter authors examine specific aspects of plastic in action. How are multiple plastic realities enacted? What are their effects? This book will be of interest to students and scholars of sociology, human and cultural geography, environmental studies, consumption studies, science and technology studies, design, and political theory.