The interest in control of nonlinear partial differential equation (PDE) sys tems has been triggered by the need to achieve tight distributed control of transport-reaction processes that exhibit highly nonlinear behavior and strong spatial variations. Drawing from recent advances in dynamics of PDE systems and nonlinear control theory, control of nonlinear PDEs has evolved into a very active research area of systems and control. This book the first of its kind- presents general methods for the synthesis of nonlinear and robust feedback controllers for broad classes of nonlinear PDE sys tems and illustrates their applications to transport-reaction processes of industrial interest. Specifically, our attention focuses on quasi-linear hyperbolic and parabolic PDE systems for which the manipulated inputs and measured and controlled outputs are distributed in space and bounded. We use geometric and Lyapunov-based control techniques to synthesize nonlinear and robust controllers that use a finite number of measurement sensors and control actuators to achieve stabilization of the closed-loop system, output track ing, and attenuation of the effect of model uncertainty. The controllers are successfully applied to numerous convection-reaction and diffusion-reaction processes, including a rapid thermal chemical vapor deposition reactor and a Czochralski crystal growth process. The book includes comparisons of the proposed nonlinear and robust control methods with other approaches and discussions of practical implementation issues."

This groundbreaking book is the first comparative analysis of the relative strengths of global bioregions. Growth Cultures investigates the rapidly growing phenomena of biotechnology and sets this study within a knowledge economy context. Philip Cooke proposes a new knowledge-focused theoretical framework, 'the New Global Bioeconomy', against which to test empirical characteristics of biotechnology. In this timely volume, Cooke unifies concepts from the sociology of science, economic sociology and evolutionary economic geography to focus on the problems and prospects for policy agencies worldwide trying to build 'biotechnology clusters'. He develops a superior policy approach of thinking in terms of platforms that integrate proximities and pipelines, which will be of significant interest for the scientific and technological communities as well as economic development policy communities. Growth Cultures will make fascinating reading for students, policy makers and researchers across management and business studies, innovation and knowledge studies, sociology, science and technology policy, applied economics, development studies and regional science.

The internationalization of research and technology is one key component of the globalization of trade and business, with potentially major impacts on patterns of economic development and public policies worldwide. Particularly in the already highly globalized pharmaceutical industry, innovation processes have changed considerably in the last 15 - 20 years. One-dimensional, linear single-actor type processes are being replaced by multi-dimensional, complex, multi-actor schemes. As a consequence, new players are becoming more important, with biotechnology firms playing a key role. This study analyzes these new ways in drug development in pharmaceuticals within the concept of "national systems of innovations" as well as from the perspectives of different actors, and collects a lot of empirical evidence for the assumed type of changes, its repercussion on significant input measures and on the differing performance of national pharmaceutical industries.

This book presents the findings of systematic research into the healthcare medicine management policies of China. In-depth comprehensive research has been carried out, targeting multiple issues of particular importance in healthcare medicine management, such as the purchasing, pricing, payment, usage, and the function of commercial healthcare insurance in medical payment. The book goes on to put forward policy advice regarding the aforementioned issues.

Where and who do we want to be? How might we get there? What might happen if we stay on our current course? The Future of Stuff asks what kind of world will we live in when every item of property has a digital trace, when nothing can be lost and everything has a story. Will property and ownership become as fluid as film is today: summoned on demand, dismissed with a swipe? What will this mean for how we buy, rent, share and dispose of stuff? About what our stuff says about us? And how will this impact on us, on manufacturing and supply, and on the planet? This brief but mighty book is one of five that comprise the first set of FUTURES essays. Each standalone book presents the author's original vision of a singular aspect of the future which inspires in them hope or reticence, optimism or fear. Read individually, these essays will inform, entertain and challenge. Together, they form a picture of what might lie ahead, and ask the reader to imagine how we might make the transition from here to there, from now to then.

The author captures the evolution of Indian industrial capitalism by extending the 'models of capitalism' and 'regulation framework'. Using principally the auto industry and anchoring the analysis to the expansion of markets, he demonstrates that the Indian state and businesses have been important institutions for creating markets. He acknowledges significant market growth, but also underscores several contradictions arising from such capitalist development. There is a wealth of data, which scholars, policymakers, and businesses will find very useful.

It's the new rock and roll. It's the new black. Sustainability is trendy, and not just among hipsters and pop stars. The uncool chemical sector helped pioneer it, and today, companies inside and outside the sector have embraced it. But what have they embraced? Surely not the Brundtland definition of meeting "the needs of the present without compromising the ability of future generations to meet their own needs."

Sustainability describes a change in the chemical industry's approach to the external world: to regulators, to greens, to neighbors, to investors and to the general public. Displacing the adversarialism of the 1970s-80s, sustainability is a new approach to social/political conflict, and an attempt to rebuild the industry's long-suffering public image. In practice, it consists of:
A 'stakeholder' approach to communications and external relations
A rebranding of regulatory compliance and risk management, with the emphasis on their benefits to stakeholders
Recognition (and even celebration) of the opportunities, not just the costs, of environmental and social protection

The core of this book is a survey of the world's 29 largest chemical companies: how they put sustainability into action (six of the 29 do not), and the six 'sustainability brands' they have created. It begins with a history of stakeholders conflict, before looking at various definitions of sustainability - by academics, by the public and by investors. After the survey and analysis, the book covers sustainability and 'greenwash' plus the ROI of sustainability, and it gives five recommendations.

Vaccine development is a complex and time consuming process that differs from the development of conventional pharmaceuticals. Primarily, vaccines are intended for use in healthy individuals as a preventative measure, requiring a long and rigorous process of research and many years of testing and development prior to clinical trials and regulatory approval. The average time for the development of vaccines to clinical is 12 to 15 years. Vaccine Development: From Concept to Clinic is a detailed overview of the development of new vaccines, covering the entire process and addresses all classes of vaccines from a processing, development and regulatory viewpoint. Utilising successful case studies the book will provide insight to the issues scientists face when producing a vaccine, the steps involved and will serve as an ideal reference tool regarding state-of-the-art vaccine development. This book is an ideal companion for any researchers working in vaccine discovery and development or with an interest in the field.

The business of food and drink is, for better and worse, the business of our nation and our planet, and to most consumers how it works remains largely a mystery. This encyclopedia takes readers as consumers behind the scenes of the food and drink industries. The contributors come from a wide range of fields, and the scope of this encyclopedia is broad, covering from food companies and brands to the environment, health, science and technology, culture, finance, and more. The more than 150 essay entries also cover those issues that have been and continue to be of perennial importance. Historical context is emphasized and the focus is mainly on business in the United States. Most entries include Further Reading. The frontmatter includes an Alphabetical List of Entries and a Topical List of Entries to allow the reader to quickly find subjects of interest. Numerous cross-references in the entries and blind entries provide other search strategies. The person and subject index is another in-depth search tool. Sample entries: Advertising, Agribusiness, Altria, Animal Rights, Betty Crocker, Celebrity Chefs, Chain Restaurants, Commodities Exchange, Cooking Technology, Culinary Tourism, Eco-terrorism, Environmental Protection Agency, Ethnic Food Business, European Union, Flavors and Fragrances, Food Safety, Food Service Industry, Genetic Engineering, Internet, Labor and Labor Unions, Marketing to Children, McDonald's, Meat Packing, North American Free Trade Agreement, Nutrition Labeling, Organic Foods, Poultry Industry, Slow Food, SPAM, Television, Trader Joe's, Tupperware, TV Dinners, Whole Foods, Williams-Sonoma, Wine Business

Licensing, Selling and Finance in the Pharmaceutical and Healthcare Industries is an assessment of the turbulent state of pharmaceutical and biotechnology markets as we enter the second decade of the 21st Century. At the same time, the book offers a cautionary evaluation of the future financing of innovation in terms of what's gone wrong and how to succeed in the future. Martin Austin explores the challenge that the pharmaceutical (and related) industries face in terms of balancing short term, cost containment and expenditure control in areas such as internal research and development; whilst embracing in-licensing and the acquisition of innovative therapies to counteract their impending portfolio weaknesses in the mid to longer term. The first part of the book provides an engaging and convincing perspective on the context in which the industry currently finds itself; the second part is a pragmatic guide to commercialising your intellectual property; including how to recognise and value what you have as well as the new ways of working that you will need to adopt when negotiating, collaborating and contracting in partnership and alliance with others. Commentators have described in great detail the cocktail of commercial, clinical and social issues that threaten to overwhelm the pharmaceutical industry; Martin Austin's book offers a very distinctive perspective on these issues and their solution.

This edited collection, first published in 1985, deals with a number of the major themes central to the study of industrial geography. Topics under discussion include new methodologies, the growing service industries, foreign investment and the industrial geography of the developing world. With a detailed introduction from Michael Pacione and comprehensive coverage, the title reflects the extent to which the field of industrial geography changed over the second half of the twentieth century in response to economic change, incorporating the growth of multinational enterprises and the influence of globalisation, alongside traditional discussion of the manufacturing industry. Providing an essential background to developments in industrial geography, this title will be valuable to students with an interest in the economics, characteristics and advancement of industrial change.

This is a brilliant examination of the complex processes of the post-1990 transformation in the Czech automotive industry and its selective integration into the West European system. The post-1990 restructuring of the industry is analyzed in the context of its pre-1990 development and in the context of the East European automobile industry as a whole. Specifically, the book examines the development and post-1990 restructuring of the Czech car, components, and truck industries.

A detailed examination of China's increasingly important chemical and pharmaceutical industry. Numerous case studies describe how western companies, such as BASF, Bayer, Bicoll, Ciba, Degussa, DSM and Novartis are managing their market entry in China.

This volume analyses the multinational enterprise using the example of the world motor industry. It begins by examining the multinational enterprise in general, considering its nature, the economic theory of its behaviour and is effects on the nation state. It goes on to explore the growth and development of the multinational motor industry, and then surveys the state of the motor industry, and the role of multinationals in it, in various types of economy, using case studies from the UK, USA, Canada, Australia, Brazil and India.

General Motors, the largest corporation on earth today, has been the owner since 1929 of Adam Opel AG, Russelsheim, the maker of Opel cars. Ford Motor Company in 1931 built the Ford Werke factory in Cologne, now the headquarters of European Ford. In this book, historians tell the astonishing story of what happened at Opel and Ford Werke under the Third Reich, and of the aftermath today. Long before the Second World War, key American executives at Ford and General Motors were eager to do business with Nazi Germany. Ford Werke and Opel became indispensable suppliers to the German armed forces, together providing most of the trucks that later motorized the Nazi attempt to conquer Europe. After the outbreak of war in 1939, Opel converted its largest factory to warplane parts production, and both companies set up extensive maintenance and repair networks to help keep the war machine on wheels. During the war, the Nazi Reich used millions of POWs, civilians from German-occupied countries, and concentration camp prisoners as forced laborers in the German homefront economy. Starting in 1940, Ford Werke and Opel also made use of thousands of forced laborers. POWs and civilian detainees, deported to Germany by the Nazi authorities, were kept at private camps owned and managed by the companies. In the longest section of the book, ten people who were forced to work at Ford Werke recall their experiences in oral testimonies. For more than fifty years, legal and political obstacles frustrated efforts to gain compensation for Nazi-era forced labor; in the most recent case, a $12 billion lawsuit was filed against the computer giant I.B.M. by a group of Gypsy organizations. In 1998, former forced laborers filed dozens of class action lawsuits against German corporations in U.S. courts. The concluding chapter reviews the subsequent, immensely complex negotiations towards a settlement - which involved Germany, the United States, Poland, Russia, Ukraine, Belarus, Czech Republic, Israel and several other countries, as well as dozens of well-known German corporations.

By concentrating on one of the key locations of global manufacturing, this volume offers a contribution to contemporary industry studies.

The rates of growth that have characterized the southern Guangdong province in the last three decades are unique, even with respect to the more general and often cited Chinese experience. But what role have governments played in these decades of growth? What are the aims and tools of industrial policies promoted in this core location of contemporary manufacturing? And what are the implications of the Guangdong experience of growth for the international debate on contemporary industry?

Referencing the international debate on industrial development, specialized Chinese academic literature, official government documents, statistics and in-depth fieldwork this book offers unique view on the complex set of long-term national and local government plans and policies that have gone hand in hand with the last three decades of impressive change in this highly industrialized region. In this framework, local industrial development policy, innovation policy and migration policy are carefully analyzed as three of the main strategic interventions selected by government authorities to promote the desired gradual structural change and technological upgrading in industry.

This book will be of interest to students and scholars of Chinese studies, economics and business, development policy and industrial policy. Furthermore, the volume presents stimulating material for both policy makers and entrepreneurs.

China today has the largest communist political regime and one of the most dynamic, fastest-growing, and largest economies in the world. Using a case study of China's tobacco industry, this book analyses how the Chinese government was able to cultivate big state-owned firms that have successfully embraced the global market. The success of the Chinese economy and the many state-owned firms within it have given rise to a "Beijing Consensus," challenging almost every principle enshrined in the so-called "Washington Consensus" that espouses private ownership, free markets, and democracy. By examining two important political processes in contemporary China, 'local state competition' and 'global-market building', the book argues that the first process serves as a crucial basis for the second. It illustrates how the local governments involved themselves in building and shaping the tobacco market throughout the 1980s and 1990s, and how these domestic market dynamics created conditions for China's recent embrace of the international market. Offering an in-depth exploration of the political-economic processes in a key Chinese state industry, the book emphasizes that the key to understanding China's political transition is to look at how the state has been shaped by its market-building projects both domestically and globally. It presents an important contribution to studies on Chinese Business and International Political Economy.

Issues relating to the size of firms in manufacturing are central to the discussion of development strategies. This book offers an interpretation of growth trajectories in selected Asian economies in terms of the size-structure of enterprises in the manufacturing sector of these economies.

The book presents a comparative survey of distribution of enterprises by size across Asia, including India, Japan, Taiwan, Korea, Thailand, Bangladesh and Vietnam. A broad survey of official data on the size structure of manufacturing helps to identify three distinct patterns of manufacturing sector development and makes the connection between enterprise development and the overall impact on the economy. The book goes on to investigate the problem of the peculiar dual size structure of manufacturing in India, with its two modes at the low and high end of the size distribution and conspicuous missing middle, and the effect that this has on the economy. This pattern is contrasted with the East Asian, model with a more even size distribution, and the more recent experience of the newly developing countries of Asia with size distribution skewed to the right. It is an important contribution to studies on Asian Economics and Manufacturing Industries.

This guide concentrates on companies engaged in food manufacturing in Britain. These include those quoted on the London Stock Exchange, the Unlisted Securities Market and some of the larger private companies. Companies based in Eire are not included unless a parent company exists in Britain.

Why have food crises seemingly become more frequent in recent years, compared to the last few decades? This book examines an array of different issues and distortions that are causing food supply chain dysfunction in many countries, particularly for staple non-perishable foods such as grains, oilseeds, pulses and sugar. It outlines the underlying changes that are currently occurring, which will have an influence on the direction of future food supply chains, and provides some solutions to current food security problems. Based on an analysis of total regulation in the 1950s-60s through to deregulation during the 1980-90s, as well as post-deregulation, it focuses on liberal trade and deregulation as a more successful solution to creating efficiencies in food supply chains and distribution. The author highlights a common thread of either farmers using government for vested-interest intervention, or autocratic governments seeking market and supply-chain power.

The book examines the role of government after 70 years of food supply chain intervention. It discusses the role of commercial trade markets and cluster industries and how these can quickly disintegrate when price distortions occur. The author studies both food importing and exporting countries and concludes that comingled commoditization of food has led to increased hoarding, corruption, and dependence on food aid. He argues that a competitive food supply chain that has minimum intervention is more likely to provide future food security. In conclusion the book emphasizes that adequate rewards, competition, and striving for supply chain efficiencies are the essences of sustainable food security.

Given the widely-accepted premise that free trade is the best means of maximising overall societal welfare, why has it proven so difficult to achieve in certain industries? This book tackles arguably the most perennial and deep-rooted of all questions in political economy, and questions the incumbent orthodox liberal theories of collective action. Using a historical institutionalist framework to explore and explain the political economy of trade protectionism and liberalization, this book is based on detailed case studies of the textiles and clothing sector in the EU, United States, China, Caribbean Basin and sub-Saharan Africa. From this, the book expands to discuss the origins of trade protectionism and examine the wider political effects of liberalization, offering an explanation of why a successful conclusion to the WTO 'Doha' round has proven to be so elusive. The book argues that the regulation of global trade - and the economic consequences that this has for both developed and developing countries - has been the result of the particular way in which trade preferences are mediated through political institutions. The Global Political Economy of Trade Protectionism and Liberalization will be of interest to those studying and researching international and comparative political economy, developing area studies, economics, law and geography.

This highly topical book brings together some of the world's leading specialists on the global car industry who discuss the ins and outs of the faster lane of regionalism at a time that the world is reassessing the ins and outs of globalization. It provides a thorough and up-dated mapping of the worldwide geography of the car industry, in the triad regions (Europe, North America and Japan), and in the emerging countries and regions.