Tobacco addresses the many interrelated controversies surrounding the historical and current use of tobacco and presents a clear, objective, and thorough treatment of this contentious public health and legal issue. The American Indians valued tobacco as a wonder drug. When Rodrigo de Jerez, who accompanied Christopher Columbus on his maiden voyage of 1492, returned to Spain with tobacco, he was accused of associating with Satan and imprisoned when his compatriots saw smoke coming out of his nose. This book covers everything from the history of tobacco to health and social issues such as targeting children. Biographical sketches of key personalities associated with tobacco range from Thomas Edison, who refused to hire anybody who smoked cigarettes, to Jean Nicot, the French Ambassador to Portugal in the mid-1500s, from whose name the word nicotine is derived. This title takes the reader through the myriad of issues that make up the tobacco debate in a clear and unbiased way. A chronology of developments in the history of tobacco use from 1570, when Belgium, Spain, Italy, Switzerland, and England were already growing tobacco, to the March 27, 2000 legal decision awarding $10 million to a woman who had smoked for 25 years despite warning labels on cigarette packaging A selection of primary source documents from the World Health Organization, the Center for Disease Control and Prevention, the World Bank, tobacco companies, and antitobacco activists

This monograph adresses the challenge of the environmental assessment of leightweight electric vehicles. It poses the question whether the use of lightweight materials in electric vehicles can reduce the vehicles' environmental impact and compares the environmental performance of a lightweight electric vehicle (LEV) to other types of vehicles. The topical approach focuses on methods from life cycle assessment (LCA), and the book concludes with a comprehensive concept on the environmental assessment of LEVs. The target audience primarily comprises LCA practitioners from research institutes and industry, but it may also be beneficial for graduate students specializing in the field of environmental assessment.

In less than 30 years, the Japanese automobile industry has risen from obscurity to become the world's leading automobile producer. This bibliography, which lists over 600 English-language titles, focuses on the Japanese automobile industry and its development in the postwar era, especially the period of mass expansion from 1980 to the present. It touches particularly on topics pertaining to the Japanese automobile industry as it relates to the U.S. automobile industry, including the operation of the two industries, Japanese transplants in the United States, and government trade issues. It also features case studies of major Japanese automobile manufacturers. Coverage includes books, articles, conference papers, periodicals, government documents, and audio-visual materials. Entries are fully annotated, and the work is indexed.

The United States is becoming an information-based, service economy with fewer middle-income jobs than in an industrial economy. How does increasing service sector employment affect community income and thus social well-being? This well-documented study assesses the impact of changing levels of employment in the service and manufacturing sectors on the level and distribution of community income. The study includes both analyses of low-wage and high-wage service and manufacturing sectors and analyses of major segments of the service sector, including business services and retail trade. Measures of social well-being include changes in community aggregate income, aggregate wages and salaries, distribution of income within the community, and the community's position in the regional hierarchy. Particular attention is given to differences in impact on rural and urban communities. The book will be of interest to those concerned with rural economic development and issues related to inequality and economic and industrial change.

"Dogfight "examines the intense rivalry of the past two decades between the European Airbus consortium and the major U.S. aircraft manufacturers, Boeing and McDonnell Douglas. From the Americans' point of view, Airbus has been heavily subsidized by its supporting governments--indeed nearly nationalized--and not exposed to the risks and disciplines of the market place. From the European perspective, Airbus has been a standard-bearer for European technological, manufacturing, and marketing prowess in the face of historical American industrial domination. This dispute has spilled over the bounds of the purely commercial and become a serious transatlantic trade issue.

Although there has been a certain amount of admiring writing about Airbus in Europe, there has been no previous attempt to weigh the issues even-handedly by exploring them on both sides of the Atlantic. Dogfight examines the roots of the conflict in the middle sixties and carries the story forward to the tentative agreement on some of the outstanding issues reached by the U.S. administration and the European Commission in the spring of 1992. In placing the controversy in its political and international context, the author has had access to many of the key players in the industry in both Europe and the United States and has interviewed a large number of politicians, officials, and senior airline and aircraft executives.

Oliver Wight is one of the pioneers of Manufacture Resource Planning (MRPII). Here he introduces the essential concepts and benefits of MRPII in a practical format with easy-to-follow question-and-answer format. Among MRPII topics covered are: how MRPII can benefit a business, the executive's leadership role in implementation, the requirements of a successful MRPII implementation, guidelines for making MRPII effective in any organization, and managing MRPII for long-term competitive advantage.

This is the first book to deal with the innovative technologies in the field of textiles and clothing sustainability. It details a number of sustainable and innovative technologies and highlights their implications in the clothing sector. There are currently various measures to achieve sustainability in the textiles and the clothing industry, including innovations in the manufacturing stage, which is the crux of this book.

This collection takes the perspective that the historiography of science, technology, and medicine needs a broader approach toward regulation. The authors explore the distinct social worlds involved in regulation, the forms of evidence and expertise mobilised, and means of intervention chosen to tame drugs in factories, consulting rooms and courts.

Gale explains why international negotiations have not produced a sustainable solution to tropical rainforest degradation. Using an innovative, critical approach to international regimes, the author analyzes the structure and operation of the International Tropical Timber Organization (ITTO). He shows how the timber industry and producing- and consuming-country governments created a blocking alliance that favoured developmentalist interests and ideas. The ITTO bolstered this alliance by permitting environmentalists merely to voice, but not to negotiate, their concerns.

Recent years have seen intense debates among management and academics on the rise of `lean production' and `Japanization'. This book examines in detail the actual practice of transfer and adaptation of productive models into the auto industry. Case studies cover in detail the Japanese transplant experience in North America, and the global experience of hybrid production systems in Europe, Latin America, and Asia.

This comprehensive reference covers the impact of dietary phosphorus in phosphorus physiology, public health and the pathogenesis of disease. Divided into three parts, the first section is an overview of the history of phosphorus and the regulation of phosphorus homeostasis. The second section focuses on specific matters related to phosphorus in the food supply. Clinical applications of the material presented in the preceding sections are pulled together in the third section - including the importance of both phosphorus excess and phosphorus deficiency for the pathogenesis of a wide variety of disease including kidney, cardiovascular, bone and oncologic diseases. Clinical Aspects of Natural and Added Phosphorus in Foods is an indispensable resource for understanding the growing importance of dietary phosphorus content in health and disease, enhancing patient care and moving forward the field of phosphorus science.

Are state and local economic incentives to attract new firms worthwhile? Mitsubishi Motors in Illinois provides in-depth analysis of the incentives offered to land Diamond-Star Motors, the plant's labor force, supplier organization, and its community impact to answer this question. The authors conclude with a benefit-cost analysis of the incentive package at the community and at the state level. Written in nontechnical language, the book is intended for planners and administrators in state and local government, economic and business development officers, and international corporate management, as well as economists and public policy analysts.

Although much research has been compiled separately on the various issues surrounding the establishment of Japanese auto manufacturing plants in the United States, this work is unique for its direct surveys of workers, suppliers, members of the community, and city and state leaders involved in the negotiations. Data on the local housing impact are drawn from detailed examination of loan applications in the community during the major hiring period at the plant. While some results confirm previous work, the authors find many differences, particularly in the composition of the labor force and the effect of just-in-time production methods on supplier location. The book provides a comprehensive view of the community and regional impact of a Japanese auto manufacturing plant which can be used as a model for planning economic development strategies to attract new firms to states and communities. Written in nontechnical language, the book is intended for planners and administrators in state and local government, economic and business development officers, and international corporate management, as well as economists and public policy analysts.

"Reconnecting Consumers, Producers and Food" presents a detailed and empirically grounded analysis of alternatives to current models of food provision. The book offers insights into the identities, motives and practices of individuals engaged in reconnecting producers, consumers and food. Arguing for a critical revaluation of the meanings of choice and convenience, "Reconnecting Consumers, Producers and Food" provides evidence to support the construction of a more sustainable and equitable food system which is built on the relationships between people, communities and their environments.

In recent years, professionals have combined nutrition, health, and engineering sciences to develop new technologies within the food industry. As we are beginning to shift focus on how we view the health benefits of various food products, perseveration and processing techniques have become much more vital. New developments regarding how we store and preserve food are emerging rapidly, making it necessary for research to be done that studies the latest scientific improvements and contemporary methods of food processing. Technological Developments in Food Preservation, Processing, and Storage is a collection of innovative research on the latest developments and advancements of preservation technologies and storage methods within the food processing industry. While highlighting topics including nutritional supplements, microfiltration, and thermal technology, this book is ideally designed for biologists, nutrition scientists, health professionals, engineers, government officials, policymakers, food service professionals, industry practitioners, researchers, academicians, and students.

Food production and consumption processes are largely governed via control mechanisms that affect food accessibility and environmental efficiency. Food resource marginalization, inequality, and deleterious consumption urgently require new governance and developmental systems that will provide food security and create consumption patterns that protect the natural environment and food resources. Global Food Politics and Approaches to Sustainable Consumption: Emerging Research and Opportunities is an essential reference source that discusses the challenges and solutions of food security and consumption control. Food politics can be linked to persistent challenges of inequitable access, food resource inefficiency, and control and consumption, which form part of the local development realities that can address global sustainable development. While highlighting topics such as rural agriculture, capitalism, and food chain management, this publication is ideally designed for policymakers, sustainable developers, politicians, ecologists, environmentalists, corporate executives, farmers, and academicians seeking current research on the policies and modalities of food efficiency and equality.

The scale and complexity of research and practices of open innovation mandate a correspondingly sophisticated form of decision making. Strategic Planning Decisions brings together a number of tools that ease the decision process in technology companies, providing both conceptual frameworks and practical applications.

Innovative approaches are presented such as an ontology-based model where all the relevant aspects of a potential technology are interrelated to provide a comprehensive and logically connected data pool for decision makers. Divided into two sections, Strategic Planning Decisions describe both strategic approaches using the decision tools, and tactical approaches. Some of these tools are expanded while some others are embedded in a model that will lay the ground for practical application. These include:

bibliometric analysis,
ontology,
roadmapping,
lead user, six sigma, and
multi-actor & multi-objective decision making methods

Recent research and relevant theory are balanced with up to date practical applications and hands on techniques making Strategic Planning Decisions ideal for engineers who wish to keep up to date with current ideas in the field of TM. It also provides workable methods for practising managers from all levels who wish to apply a more rigorous approach in their work and consultants concerned with technology assessment and its management."

Corporate Social Responsibility (CSR) is an important element in creating competitive advantages for enterprises in different sectors. The authors guide readers through the different cases studies in order to present the benchmarking of international standards and CSR initiatives, as well as CSR performance evaluation practices. This book aims to identify current problems that can arise during CSR implementation in manufacturing and services companies. Moreover some best practice examples suitable for the introduction of CSR in the small and medium size companies will be described. The authors show how different stakeholders can benefit from sustainable resource management and pro-social behaviors. This book will be a valuable resource for both academics and practitioners who want to deepen their knowledge of CSR. This scientific monograph has been doubled blind reviewed.

Though their usage greatly diminished at the dawn of the scientific area, Indian spices were traditional parts of healthcare for thousands of years. However, over the last decade, largely due to the growth in popularity of complementary and alternative medicine, spices have regained attention due to their physiological and functional benefits. By applying modern research methods to traditional remedies, it is possible to discover what made these spices such effective ailment treatments. Ethnopharmacological Investigation of Indian Spices is a collection of innovative research that analyzes the chemical properties and medical benefits of Indian spices in order to design new therapeutic drugs and for possible utility in the food industry. The book specifically examines the phytochemistry and biosynthetic pathway of active constituents of Indian spices. Highlighting a wide range of topics including pharmacology, antioxidant activity, and anti-cancer research, this book is ideally designed for pharmacologists, pharmacists, physicians, nutritionists, botanists, biotechnicians, biochemists, researchers, academicians, and students at the graduate and post-graduate levels interested in alternative healthcare.

This textbook is written as a unified approach to various topics, ranging from drug discovery to manufacturing, techniques and technology, regulation and marketing. The key theme of the book is pharmaceuticals - what every student of pharmaceutical sciences should know: from the active pharmaceutical ingredients to the preparation of various dosage forms along with the relevant chemistry, this book makes pharmaceuticals relevant to undergraduate students of pharmacy and pharmaceutical sciences.
This book explains how a particular drug was discovered and then converted from lab-scale to manufacturing scale, to the market. It explains the motivation for drug discovery, the reaction chemistry involved, experimental difficulties, various dosage forms and the reasoning behind them, mechanism of action, quality assurance and role of regulatory agencies. After having a course based on this book, the student will be able to understand: 1) the career prospects in the pharmaceutical industry, 2) the need for interdisciplinary teamwork in science, 3) the techniques and technology involved in making pharmaceuticals starting from bulk drugs, and 4) different dosage forms and critical factors in the development of pharmaceutical formulations in relation to the principles of chemistry.
A few blockbuster drugs including atorvastatin, sildanefil, ranitidine, ciprofloxacin, amoxicillin, and the longest serving drugs such as aspirin and paracetamol are discussed in detail. Finally, the book also covers the important current pharmaceutical issues like quality control, safety, counterfeiting and abuse of drugs, and future prospects for pharmaceutical industry.
Unified approach explaining drug discovery, bulk drug manufacturing, formulation of dosage forms, with pharmacological and therapeutic actionsManufacturing processes of representative active pharmaceutical ingredients and their chemistry plus formulation of dosage forms presented in this book are based on actual industrial processesCovers many aspects relevant to students of the pharmaceutical sciences or newly employed pharmaceutical researchers/employees. It contains summary information about regulatory agencies of different countries

MATLAB(r) in bioscience and biotechnology presents an introductory Matlab course oriented towards various collaborative areas of biotechnology and bioscience. It concentrates on Matlab fundamentals and gives examples of its application to a wide range of current bioengineering problems in computational biology, molecular biology, bio-kinetics, biomedicine, bioinformatics, and biotechnology. In the last decade Matlab has been presented to students as the first computer program they learn. Consequently, many non-programmer students, engineers and scientists have come to regard it as user-friendly and highly convenient in solving their specific problems. Numerous books are available on programming in Matlab for engineers in general, irrespective of their specialization, or for those specializing in some specific area, but none have been designed especially for such a wide, interdisciplinary, and topical area as bioengineering. Thus, in this book, Matlab is presented with examples and applications to various school-level and advanced bioengineering problems - from growing populations of microorganisms and population dynamics, reaction kinetics and reagent concentrations, predator-prey models, mass-transfer and flow problems, to sequence analysis and sequence statistics.
This is the first book intended as a manual introducing biologists and other biotechnology engineers to work with MatlabIt is suitable for beginners and inexperienced users; however, applications of Matlab to advanced problems such as the Monte Carlo method, curve fitting, and reliable machine diagnostics make the book relevant to university teachers as wellThe book is different in that it assumes a modest mathematical background for the reader and introduces the mathematical or technical concepts with a somewhat traditional approach; Matlab is then used as a tool for subsequent computer solution

"Presenting findings from research into Sweden's leading multinationals this book focuses on engineering companies operating in global industries such as pharmaceutical, aerospace, packing systems and automotive. It explores research and practice within the area of HRM focusing on project-based organizations"--

This book explores the business history of three major independent American automakers - Nash Motor Company, the Hudson Motor Car Company, and the American Motors Company - that faced fierce competition from the 'Big Three'. With roots extending back to the first decade of the twentieth century, Nash Motor Company and the Hudson Motor Car Company managed to compete and even prosper as independent producers until they merged in 1954 to form the American Motors Company, which itself remained independent until it was bought in 1987 by the Chrysler Corporation. In "Storied Independent Automakers", renowned automotive scholar Charles K. Hyde argues that these companies, while so far neglected by auto history scholars, made notable contributions to automotive engineering and styling and were an important part of the American automobile industry. Hyde investigates how the relatively small corporations struggled in a postwar marketplace increasingly dominated by the giant firms of Ford, General Motors, and Chrysler, which benefited from economies of scale in styling, engineering, tooling, marketing, and sales. He examines the innovations that kept the independents' products distinctive from those of the Big Three and allowed them to survive and sometimes prosper against their larger competitors. Hyde also focuses on the visionary leaders who managed the companies, including Charles Nash, Roy D. Chapin, Howard Coffin, George Mason, George Romney, and Roy D. Chapin Jr., who have been largely unexamined by other scholars. Finally, Hyde analyzes the ultimate failure of the American Motors Company and the legacy it left for carmakers and consumers today. "Storied Independent Automakers" is based on extensive research in archival collections generated by the three companies. Residing in large part in the DaimlerChrysler Corporate Collection, these sources have been seldom tapped by other scholars before this volume. Auto historians and readers interested in business history will enjoy "Storied Independent Automakers".

This book explores food traceability in raw materials, additives and packing of the dairy sector and it provides an accessible and succinct overview of the new Extended Traceability (ExTra) software. In this work, the authors present several practical examples of extended food traceability for edible products and food-contact materials in the cheese-making industry. Readers will also discover a summary of the existing legal and regulatory requirements for food traceability in Europe. This book will appeal to a wide readership, from academic researchers to professionals and auditors in industry working in quality control, food and packing traceability, and international regulation.