In 1950, a diagnosis of cancer was all but a death sentence. Mortality rates only got worse, and as late as 1986, an article in the New England Journal of Medicine lamented: We are losing the war against cancer." Cancer is one of humankind's oldest and most persistent enemies it has been called the existential disease.But we are now entering a new, and more positive, phase in this long campaign. While cancer has not been cured,and a cure may elude us for a long time yet,there has been a revolution in our understanding of its nature. Years of brilliant science have revealed how this individualistic disease seizes control of the foundations of life,our genes,and produces guerrilla cells that can attack and elude treatments. Armed with those insights, scientists have been developing more effective weapons and producing better outcomes for patients. Paul A. Marks, MD, has been a leader in these efforts to finally control this devastating disease.Marks helped establish the strategy for the war on cancer" in 1971 as a researcher and member of President Nixon's cancer panel. As the president and chief executive officer for nineteen years at the world's pre-eminent cancer hospital, the Memorial Sloan-Kettering Cancer centre, he was instrumental in ending the years of futility. He also developed better therapies that promise a new era of cancer containment. Some cancers, like childhood leukemia and non-Hodgkin's lymphoma, that were once deadly conditions, are now survivable,even curable. New steps in prevention and early diagnosis are giving patients even more hope. On the Cancer Frontier is Marks' account of the transformation in our understanding of cancer and why there is growing optimism in our ability to stop it.

This is the story of the radical intervention carried out by the Thatcher administration in response to 1986-89 Monopolies and Mergers Commission inquiry into brewing. It describes the creation of big brewers, the official investigations into what many saw as an uncompetitive structure and the damaging consequences for consumers and licensees.

Overall, this first volume in the series should render business research in manufacturing a good deal easier by bringing together insightful industry histories and detailed critical bibliographies. This series has much to recommend it. Future volumes will be eagerly awaited. Reference Books Bulletin This historical and bibliographical reference work is the first volume of Greenwood Press's Handbook of American Business History, a series intended to supplement current bibliographic materials pertaining to business history. Devoted to manufacturing, this work uses the Enterprise Standard Industrial Classification (ESIC) to divide the subject into distinct segments, from which contributors have developed histories and bibliographies of the different types of manufacturing. Though authors were given sets of guidelines to follow, they were also allowed the flexibility to work in a format that best suited the material. Each contribution in this volume contains three important elements: a concise history of the manufacturing sector, a bibliographic essay, and a bibliography. Some contributions appear in three distinct parts, while others are combined into one or two segments; all build on currently available material for students and scholars doing research on business and industry. The contributors, who include business, economic, and social historians, as well as engineers and lawyers, have covered such topics as bakery products, industrial chemicals and synthetics, engines and turbines, and household appliances. Also included are an introductory essay that covers general works and a comprehensive index. This book should be a useful tool for courses in business and industry, and a valuable resource for college, university, and public libraries.

How does a market globalize? How do antitrust and trade policies speed up or slow down the process? How do firms take part in it? The book offers a comprehensive appraisal of the phenomenon from a thorough study of the cement industry. Considered as a model of spatial competition in economic textbooks and inherently local, the industry globalized in the 1980s. Hence, the originality of the book to deal with an extreme case that highlights the fundamental characteristics of globalization.

This book focuses on principles and practices in digital wine marketing. By providing a global overview of social media and e-commerce strategies and practices in the wine business, this book allows readers to understand how consumers and producers deal with these modern communication and selling platforms.

Traditional farming systems have dominated the agricultural sector for the past few centuries. However, the past few years have proven that new, non-traditional farming methods, such as passive and non-passive solar drying, are essential in the wake of diminishing food production globally. Optimizing the Use of Farm Waste and Non-Farm Waste to Increase Productivity and Food Security: Emerging Research and Opportunities is a crucial reference source that provides vital research on the application of enhanced productivity, flexibility, competitiveness, and sustainability within an individual farming enterprise to promote food security. While highlighting topics such as biogas production, food distribution network, and aquaculture diversification, this publication explores utilizing farm waste in a circular approach to optimize material utilization in a farming system to realize a zero-waste scenario and the methods individual farms can practice to operate sufficiently to become successful and contribute to the attainment of national food security. This book is ideally designed for policymakers, farmers, researchers, agriculture engineers, environmental engineers, and development specialists seeking current research on non-farm waste contributions as sources of raw materials.

In today's fast-paced and volatile business environment, customers are demanding increased flexibility and lower cost, and companies must operate in a waste-free environment to maintain a competitive edge and grow margins. Lean Enterprise is the process that companies are adopting to provide superior customer service and to improve bottom line performance. Are you contemplating Lean for your manufacturing or office facility? Are you already implementing Lean but are dissatisfied with the speed of change? Do your employees think that Lean is just the new flavor of the month? Are you being forced to go Lean by your customers or your competitors? Are you anticipating going offshore to cut costs? Regardless of your situation, this book is designed to help guide you through the Lean transformation and avoid the pitfalls. Find out why many companies are failing to live up to the promise of Lean, and why there may be alternatives to outsourcing or going offshore. Learn from the mistakes of others and avoid the trials that often kill the initiative. Find out why you must change, how to change, and how to institutionalize the process. Understand the costs of outsourcing or going offshore and compare these to the Lean alternative. For those companies that fail to commit to the process and truly change the culture, a Lean Enterprise will remain elusive. This is the revised, second edition of this highly-acclaimed book with a new foreword by Dolf Kahle, CEO of Visual Marketing Systems.

The future for all the nations of the world, whether diverse- or single-commodity countries, is bound up in effective economic development. In particular, an understanding of the relationship between a government and its private business sector is becoming an increasingly important factor in the management of economic growth. This work presents the results of a study that focuses on efforts to stimulate private industrial investment in the manufacturing sector of the Saudi Arabian economy. The conclusions help to shed light on the interplay of government-business relationships not only in Saudi Arabia, but in other developing countries as well.

The study, conducted in 1986, included a series of interviews with manufacturing executives, government officials, and chamber of commerce members. Wahib Soufi and Richard Mayer begin their analysis with an overview of government and business in Saudi Arabia, assessing the role played by Islamic law and the need for diversification. They follow this by sketching a conceptual framework for examining government-business relationships, and outlining issues relevant to promoting industrial development. A set of three chapters explore the results of the survey data, detailing the perceptions of the Saudi private business sector, comparing business and government perceptions, and finally, evaluating the effect of communications, expectations, and perceptions on the government-business relationship. The concluding chapter reexamines these conclusions on the basis of information available three years after the initial study, and is followed by a selective bibliography. This important study will be a valuable resource for corporate managers and government officials involved in economic planning, and a useful reference tool for college courses in business and economic policy and for public and academic libraries.

This book focuses on the food safety challenges in the vegetable industry from primary production to consumption. It describes existing and innovative quantitative methods that could be applied to the vegetable industry for food safety and quality, and suggests ways in which such methods can be applied for risk assessment. Examples of application of food safety objectives and other risk metrics for microbial risk management in the vegetable industry are presented. The work also introduces readers to new preservation and packaging methods, advanced oxidative processes (AOPs) for disinfection, product shelf-life determination methods, and rapid analytic methods for quality assessment based on chemometrics applications, thus providing a quantitative basis for the most important aspects concerning safety and quality in the vegetable sector.

Suicides, excessive overtime, hostility and violence on the factory floor in China. Drawing on vivid testimonies from rural migrant workers, student interns, managers and trade union staff, Dying for an iPhone is a devastating expose of two of the world's most powerful companies: Foxconn and Apple. As the leading manufacturer of iPhones, iPads and Kindles, and employing one million workers in China alone, Taiwanese-invested Foxconn's drive to dominate global electronics manufacturing has aligned perfectly with China's goal of becoming the world leader in technology. This book reveals the human cost of that ambition and what our demands for the newest and best technology mean for workers. Foxconn workers have repeatedly demonstrated their power to strike at key nodes of transnational production, challenge management and the Chinese state, and confront global tech behemoths. Dying for an iPhone allows us to assess the impact of global capitalism's deepening crisis on workers.

In recent years much has been made of the sucess of developing countries, particularly in East Asia, which have achieved economic growth by manufacturing goods which are then exported to developing economies.
"Manufacturing for Export in the Developing" "World" looks at a number of countries which have tried to affect a similar transition. It combines case studies of five countries with an introduction that considers the overall contact and conclusions. The book uncovers serious potential difficulties in maintaining the pace of manufacturing for export in the developing countries, and shows that there is no simple relationship between import liberalization and manufacturing for export.

In this study of the life and work of Saint-Nazaire's shipbuilding workers in the 30 years before World War I, Schuster shows that the consequences of industrial production for workers differed sharply according to their resources and experiences. She details the competing identities and divergent values maintained by shipbuilding workers, demonstrating that they were fostered by the interaction between state programs, industrial production, and the traditions pursued in the local realm. Third Republic economic policies for shipbuilding promoted unemployment and worker dependence on state officials over union leaders, and the uneven application of capitalist methods of production meant multiple workplace experiences that further undercut association.

A workforce composed of industrial workers and agricultural producers brought markedly different priorities to the workplace. Urban-dwelling industrial workers proved dependent on shipbuilding, while workers commuting from La Grande Bri DEGREESDere, a nearby marshland, were property-owning producers, mostly peat-cutters, with traditions of self-government and a commanding community identity. They turned to ship production precisely to maintain rural settlement and agricultural production. These divergent values and responses to industrial work, in conjunction with multiple barriers to association, generated separate and even contrary labor concerns and protests.

Velocity 2.0: Paint, Pixels, & Profitability is the second book from retail automotive industry expert, entrepreneur and former dealer, Dale Pollak. The book picks up where Dale's Velocity: From the Front Line to the Bottom Line leaves off, revealing new ROI-based management metrics and processes dealers can use to operate more efficient and profitable used vehicle departments. The book flows from the recognition that today s used vehicle marketplace is more challenging and volatile than it s ever been a tough reality driven by the power of the Internet and a troubled economy. Velocity 2.0 offers a playbook of best practices and processes to help dealers become more successful.

Only ten years ago driving was about horsepower, style and comfort -- people said they loved their cars. Today, we can see the transformation in the automotive industry including ridesharing and carsharing with the new concepts of mobility and motion changing every day. Will consumers lose the e-motion they previously had for their vehicles? Maybe the new e-motion will be a different type of connection, one that understands, learns, and reasons as you move through your life; this is the concept of a cognitive vehicle and lifestyle that is discussed within. This book provides the trends and technologies in the automotive industry as it moves from a connected vehicle to a cognitive vehicle and how automotive manufactures facing the market shift from an organizational-centered to an individual-centered economy.

Recent improvements in business process strategies have allowed more opportunities to attain greater developmental performances. This has led to higher success in day-to-day production and overall competitive advantage. The Handbook of Research on Manufacturing Process Modeling and Optimization Strategies is a pivotal reference source for the latest research on the various manufacturing methodologies and highlights the best optimization approaches to achieve boosted process performance. Featuring extensive coverage on relevant areas such as genetic algorithms, fuzzy set theory, and soft computing techniques, this publication is an ideal resource for researchers, practitioners, academicians, designers, manufacturing engineers, and institutions involved in design and manufacturing projects.

This book examines knowledge-intensive entrepreneurship (KIE) with a focus on the European textile and apparel industries. The primary purpose is to review the extant academic literature related to the European textile and apparel industries and reflect on that review empirically using a new and robust database on KIE to discover patterns between human capital and strategic entrepreneurial and innovative behavior. According to the Advancing Knowledge-Intensive Entrepreneurship and Innovation for Economic Growth and Social Well-being in Europe (AEGIS) project, KIE is defined as an interface between knowledge generation and diffusion and the productive system. Knowledge-intensive entrepreneurs are thus involved in mechanisms that translate knowledge into innovation, which in turn leads to economic development and growth within an industry and/or region. To date, KIE is often associated with high-tech industries such as aerospace, computer engineering, automotive or telecommunications. For this reason, few studies have been conducted that specifically examine KIE as an avenue for firm or sector growth in the textile and apparel industries. However, new studies have positioned these industries as ones in which KIE can foster growth through innovation, and where products and processes are often evaluated within a knowledge-based framework. Building on this growing literature base, this volume explores potential policies and strategies for driving innovation and growth at the firm and industry levels in Europe and other regions, including the United States.

This book highlights the sustainability aspects of textiles and clothing sector in light of nanomaterials and technologies. The invasion of nano in every industrial sector has been important and has made remarkable changes as well as posed new challenges, including the textiles and clothing sector. There is quite a great deal of research happening in terms of nano materials for textiles across the globe, some of which are covered in this book.

This book highlights the challenges in sustainable wet processing of textiles, natural dyes, enzymatic textiles and sustainable textile finishes. Textile industry is known for its chemical processing issues and many NGO's are behind the textile sector to streamline its chemical processing, which is the black face of clothing and fashion sector. Sustainable textile chemical processes are crucial for attaining sustainability in the clothing sector. Seven comprehensive chapters are aimed to highlight these issues in the book.

Pepsi-Cola and Coca-Cola are widely recognized as being two of the premier marketing companies in the world. They have introduced a great variety of new products and package types. They have raised celebrity advertising to a new level. Coca-Cola even changed the formula for Coke. These and other developments in the carbonated soft drink industry came about from major strategy changes by Pepsi-Cola and Coca-Cola. Rather than simply reacting to a changing competitive environment, PepsiCo and The Coca-Cola Company have created and implemented strategies that turned the new environment to their advantage. Although Pepsi-Cola attacked Coca-Cola's dominance and achieved near-parity with Coke in bottled soft drinks, both Coke and Pepsi have benefitted from fighting the Cola Wars. The battle between them has stimulated continuing growth in an industry regularly pronounced by the experts for many years to be on the verge of maturity.

One widely ignored aspect of the Cola Wars is the ongoing transformation of the soft drink distribution systems of Coca-Cola and Pepsi-Cola from systems of independent bottlers to captive bottling subsidiaries. Chandler advanced the hypothesis that successful firms develop strategies to take advantage of new opportunities, and that those strategies then determine the organizational structure required for effective implementation. We find that changes in the organization of the two leading carbonated soft drink firms' distribution systems provide support for Chandler's hypothesis. The independent bottling systems were a unique and effective organization for many decades. Changes in the external environment, however, raised the costs of transacting between the parent concentrate manufacturers and their independent bottlers. In particular, the new competitive environment required rapidly changing product and marketing strategies, and the implementation of these strategies required the close cooperation of the distribution systems. In effect, Coke and Pepsi needed to change the organization of their distribution systems to implement effectively the strategies that stimulated the new competitive environment, because the relative transaction costs of the independent bottling systems in the new environment were too high. The book presents a strategic analysis of the history of the industry.

The practical approached championed in this book have led to increasing the quality on many successful products through providing a better understanding of consumer needs, current product and process performance and a desired future state. In 2009, Frank Rossi and Viktor Mirtchev brought their practical statistical thinking forward and created the course "Statistics for Food Scientists". The intent of the course was to help product and process developers increase the probability of their project's success through the incorporation of practical statistical thinking in their challenges. The course has since grown and has become the basis of this book.

Prozac. Paxil. Zoloft. Turn on your television and you are likely to see a commercial for one of the many selective serotonin reuptake inhibitors (SSRIs) on the market. We hear a lot about them, but do we really understand how these drugs work and what risks are involved for anyone who uses them? Let Them Eat Prozac explores the history of SSRIs-from their early development to their latest marketing campaigns-and the controversies that surround them. Initially, they seemed like wonder drugs for those with mild to moderate depression. When Prozac was released in the late 1980s, David Healy was among the psychiatrists who prescribed it. But he soon observed that some of these patients became agitated and even attempted suicide. Could the new wonder drug actually be making patients worse? Healy draws on his own research and expertise to demonstrate the potential hazards associated with these drugs. He intersperses case histories with insider accounts of the research leading to the development and approval of SSRIs as a treatment for depression. Let Them Eat Prozac clearly demonstrates that the problems go much deeper than a side-effect of a particular drug. The pharmaceutical industry would like us to believe that SSRIs can safely treat depression, anxiety, and a host of other mental problems. But, as Let Them Eat Prozac reveals, this "cure" may be worse than the disease.

This third volume on detox fashion highlights sustainable wastewater treatment methods, as well as techniques used by and the adoption of detox strategies by different brands in the textile sector. These aspects are addressed in three central chapters: Sustainable Wastewater Treatment Technologies; Review of the Utilization of Plant-based Natural Coagulants as Alternatives to Textile Wastewater Treatment; and New Waste Management through Collaborative Business Models for Sustainable Innovation.