Polymer-Drug Conjugates: Linker Chemistry, Protocols and Applications discusses important concepts, fundamentals and prospective applications of 'Linker Chemistry' in a clear-and-concise manner. The book provides vital information on chemical entities binding with the drug-polymer complex for targeted drug delivery systems. It highlights roles and significance, different classes and synthetic protocols as well as mechanisms of chemical bond formation in drug-polymer conjugation in drug delivery, also offering insights into the mechanism of polymer interaction with linker and drug molecules by biodegradable chemical bonding. The protocol of binding with drug molecules is clearly explained and justified with case studies, helping researchers and advanced students in the pharmaceutical sciences understand fundamentals involved and related aspects in molecule designing for effective therapeutic benefits.

The increasing demand for food as well as changes in consumption habits have led to the greater availability and variety of food with a longer shelf life. However, these items, when not properly preserved, can lead to severe food-borne illnesses that can be fatal. Thus, countless studies are now geared towards the processing, distributing, and safe storage of foods. Novel Technologies and Systems for Food Preservation is an essential reference source that discusses novel and emerging cooling and heating technologies, processes, and systems for food preservation, as well as improvements for control and monitoring systems that aim to foster energy efficiency, equipment safety, and performance. Additionally, it looks at concepts that may be useful for the development of new policies and legislation concerning food preservation. Featuring research on topics such as energy efficiency, food quality, and legislation policies, this book is ideally designed for government officials, policymakers, food and service industry professionals, food safety inspectors, researchers, academicians, and students.

Single-Cell Omics: Volume 1: Technological Advances and Applications provides the latest technological developments and applications of single-cell technologies in the field of biomedicine. In the current era of precision medicine, the single-cell omics technology is highly promising due to its potential in diagnosis, prognosis and therapeutics. Sections in the book cover single-cell omics research and applications, diverse technologies applied in the topic, such as pangenomics, metabolomics, and multi-omics of single cells, data analysis, and several applications of single-cell omics within the biomedical field, for example in cancer, metabolic and neuro diseases, immunology, pharmacogenomics, personalized medicine and reproductive health. This book is a valuable source for bioinformaticians, molecular diagnostic researchers, clinicians and members of the biomedical field who are interested in understanding more about single-cell omics and its potential for research and diagnosis.

Safety and Practice for Organic Food covers current food safety issues and trends. It provides detailed information on all organic and pasture practices including produce-only, farm-animal-only or integrated crop-livestock farming, as well as the impact of these practices on food safety and foodborne infections. The book explores food products that organic, integrated and traditional farming systems are contributing to consumers. As the demand for organic food products grows faster than ever, this book discusses current and improved practices for safer products. Moreover, the book explores progressive directions, such as the application of next-generation sequencing and genomics to aid in the understanding of the microbial ecology of the agro-environment and how farmer education can contribute to sustainable and safe food. Safety and Practice for Organic Food is a unique source of organic agricultural practices and food production for researchers, academics and professionals at agriculture-based universities and colleges who are involved in food science, animal sciences including poultry science, food safety, food microbiology, plant science and agricultural extension. This book is also an excellent source of information for regulators and federal government officials (USDA, FDA, EPA) and the food processing industry.

Overcoming Obstacles in Drug Discovery and Development uses real-world case studies to illustrate how critical thinking and problem solving skills are applied in the discovery and development of drugs. It also shows how developing critical thinking to overcome issues plays an essential role in the process. Modern drug discovery and development is a highly complex undertaking that requires scientific and professional expertise to be successful. After the identification of a molecular entity for treating a medical condition, challenges inevitably arise during the subsequent development to understand and characterize the biological profile; feedback from scientists is used to fine-tune the molecular entity to obtain an effective and safe product. In this process, the discovery team may identify unexpected safety issues and new medical disorders for treatment by the molecular entity. Invariably inherent in this complex undertaking are miscues, mistakes, and unexpected problems that can derail development and throw timetables into disarray, potentially leading to failure in the development of a medically useful drug. Addressing critical unexpected problems during development often requires scientists to utilize critical thinking and imaginative problem-solving skills. Overcoming Obstacles in Drug Discovery and Development will be essential to young scientists to help learn the skills to successfully face challenges, learn from mistakes, and further develop critical thinking skills. It will also be beneficial to experienced researchers who can learn from the case studies of successful and unsuccessful drug development.

This book has been written for the under-graduate students of Dairy Technology course being offered by different Dairy Science Colleges and various Agricultural and Deemed Universities across the country.

Clinical Case Studies on Medication Safety provides real and simulated scenarios about safety issues related to medication, including Adverse Drug Reactions (ADRs), medication errors, and Drug Related Problems (DRPs). The book explains real-life case management, including details about adverse drug reactions, mistakes during drug administration, drug avoidance, and drug-drug interactions with a goal of improving patient care. With over 150 case studies, including cases from alternative medicine and traditional medicine, this book will help medical and health sciences educators, students, healthcare professionals, and other readers apply their knowledge and skills to solve cases for better patient care.

Formulation of Monoclonal Antibody Therapies: From Lab to Market covers a wide range of topics about therapeutic monoclonal antibodies (mAbs) with a focus on formulation aspects. Therapeutic monoclonal antibodies are used for treatment of chronic diseases. It brings together a comprehensive knowledge in one accessible volume. Starting with foundational information on monoclonal antibodies, the book then discusses the importance of biopharmaceutical products, monoclonal antibodies and biosimilars in treatment of chronic diseases, pharmaceutical aspects of mAbs, and how it can be administered. It also covers the industrial point of view and the clinical application of mAbs including in oncology, general medicine, rheumatology, hematology, dermatology, gastrointestinal tract, metabolic diseases, and dentistry. Formulation of Monoclonal Antibody Therapies: From Lab to Market is essential reading for researchers in biotechnology and biopharmaceutical fields, academics and pharmaceutical industrial scientists, and university students in pharmaceutical and biopharmaceutical sciences.

The first few s introduces the reader to the crop, its origin and distribution, varieties cultivated throughout the country and their characteristics. Later the trade of banana, both international and domestic, is explained along with the ways the fruit is consumed in different parts of the world. A exclusively deals with the nutritive and therapeutic values of banana followed by the post harvest aspects at length in seven s with all the latest scientific developments. The last three s explain about the processing and value addition including the waste/by-products utilization. The readers will find it comprehensive with all the information relevant to post harvest aspects of bananas and plantains.

Food Engineering & Technology: A Practice Book deals with objective type questions and answers. The book is aimed to provide number of questions related to almost all the main aspects of the Food Technology. Efforts have been made to cover wide range of topics in accordance to the syllabus of various competitive examinations like JRF, SRF, ARS, GATE, etc. It is expected that the book will be much sought by the students of Food Science/Technology/Engineering and related disciplines who can prepare themselves for both written as well as oral examinations. At the same time, this can be used as a readily available handbook for quick reference by practicing researchers/technologists and engineers. Besides faculty members involved in teaching Food Technology will find the book useful as a good question bank.

Fruit Breeding is an art and science demanding prolonged time, space and intrinsic qualities. Seed propagation leads to heterogeneity and asexual propagation of elite clones' leads to newer and novel types. There are temperate, sub-tropical and tropical fruits differing in photo and thermo periodic requirements. There are also parthenocarpic and apomictic fruit trees demanding special breeding methods for improvement. Aroma, taste and flavor are unique to fruits unlike other horticultural crops like vegetables, spices, plantation crops and tubers. The book unravels history of fruit breeding, biodiversity, challenges approaches and prospects, apomixes, mutation breeding, role of insects in fruit production, molecular markers, statistical techniques, rootstock breeding, breeding of mango, citrus, banana, papaya, guava, sapota, jackfruit, sugarapple/sweetsop Indian jujube and jamun. The 20 s in the book authored by 15 scientists from six Research Institutes and Universities expose readers to a new world of fruit breeding, very seldom ventured by breeders.

Concise Oxford Dictionary defines Resilience as recoiling; springing back; resuming its original shape after bending, stretching, compression etc. With five components of crop production -space, water, energy, light, nutrients- limiting, there are stresses on crops to perform at threshold input yielding optimum output. Droughts and floods, cold and heat waves, forest fires, landslides and mud slips, ice storms, dust storms, hailstorms, thunder clouds associated with lightening and sea level rise are throwing new challenges to farming. This dangerously narrow level of food base prompts to widen the base of grains, vegetables, fruits, spices, industrial crops, mushrooms and aromatic plants. The emphasis so far was more on terrestrial plants, forest plants and lesser on lower plants. The aquatic plants-fresh water, brackish water, marine- were not much explored for edible use except by Chinese and Japanese. Halophytes, bryophytes, ferns and sea weeds are so far climate resilient. The Indo-Burmese Centre of origin (Hindustan centre including North East) is abode of several plants of possible vegetable, fruit and spicy value. The New Life styles consequent to migration for employment have brought newer food and dietary patterns. The urbanization and smaller family size are leading to pre-cooked foods and visitation to restaurants. s on bryophytes, halophytes, microalgae, chasmophytes, pseudocereals, medicinal mushrooms, speciality mushrooms, palmyrah palms, bramakamal, tropical tuber crops, dragon fruits, broad dhaniya, plants for dyes, kale and ornamental ginger are authored by eminent working scientists from 21 Universities and Research Institutes in Japan and India. The crops for the future especially climate resilient are to be identified and promoted in an emerging production scenario of new life style foods and convenient speciality foods getting attention by the new generation. The present book Climate Resilient Crops for the Future carries 17 s authored by men of eminence in respective areas concerning to the above areas.

Cashew (Anacardium occidentale L. f. Anacardiaceae) is very important and dollar earning plantation crop. A systematic compilation on various aspects has been covered in this book. It consists the s viz. Introduction; History, origin and geographical distribution; Area, production, productivity, export and import; Soil and climate; Biodiversity and crop improvement; Varieties; Propagation and production of planting material; Morphology and tree characters; Pollination techniques; Establishments of cashew orchard; Mineral nutrition; Training and pruning; Rejuvenation of old orchards; Inter-cropping and cover cropping; Intercultural operation; Maturity, harvesting and yield; Post harvest storage; Marketing of raw nuts; Nutritive value of cashew; Cashew nut processing; Cashew apple processing; Pests and diseases; Economics for cashew cultivation; Future strategies along with references. This book will be helpful to students and teachers of horticulture, agriculture and forestry, scientists, researchers, cashew growers and processors including small scale processing unit holders.

The papers included in this book have a broad coverage of the topics related to new technologies in functional foods and nutraceuticals, fruits and vegetables and their by-products as valuable ingredients for functional foods and nutraceuticals, potential bioactive components from various food sources, trends and development of nutraceuticals and functional foods as well as functional food and nutraceuticals as ingredients in the value addition for health promotion, standardization and quality control. This compilation helps to overcome the problems faced in exploring the potential of nutraceuticals in naturopathy and device strategies to encounter such problems.

The objective of this book is to provide state-of-the-art knowledge, and highlight the current developments taking place in biological sciences. The book encompasses topics on prokaryotic cyanobacteria to higher plants, distributed in fourteen s for the benefit of graduate and post-graduate students as well as young researchers and scientists. Subjects covered include molecular and biochemical diversity of microbes, stress biology, cyanotoxins, antimicrobial activity of drugs originated from plants, natural bioactive compounds of microbial origin, detection approaches for genetically modified crops, genomics and proteomics. The book provides an insight for future perspectives in particular field with extensive bibliographies at the end of each . With all these, this book becomes highly useful and must-read for students, researchers and professionals in botany, biotechnology, bioinformatics, environmental sciences, agriculture, molecular biology and other streams of biological sciences.

The COVID-19 pandemic has affected the entire world in an unprecedented way since 2019. However, novel and innovative applications of various omics, computational, and smart technologies have helped manage the pandemic of the 21st century in a very effective manner. Omics approaches and technologies in COVID-19 presents up-to-date knowledge on omics, genetic engineering, mathematical and computational approaches, and advanced technologies in the diagnosis, prevention, monitoring, and management of COVID-19. This book contains 26 chapters written by academic and industry experts from more than 15 countries. Split into three sections (Omics; Artificial Intelligence and Bioinformatics; and Smart and Emerging Technologies), it brings an overview of novel technologies under omics such as, genomic, metagenomic, pangenomic, metabolomics and proteomics in COVID-19. In addition, it discusses hostpathogen interactions and interactomics, management options, application of genetic engineering, mathematical modeling and simulations, systems biology, and bioinformatics approaches in COVID-19 drug discovery and vaccine development. This is a valuable resource for students, biotechnologists, bioinformaticians, virologists, clinicians, and pharmaceutical, biomedical, and healthcare industry people who want to understand the promising omics and other technologies used in combating COVID-19 from various aspects.

A Handbook of Artificial Intelligence in Drug Delivery explores the use of Artificial Intelligence (AI) in drug delivery strategies. The book covers pharmaceutical AI and drug discovery challenges, Artificial Intelligence tools for drug research, AI enabled intelligent drug delivery systems and next generation novel therapeutics, broad utility of AI for designing novel micro/nanosystems for drug delivery, AI driven personalized medicine and Gene therapy, 3D Organ printing and tissue engineering, Advanced nanosystems based on AI principles (nanorobots, nanomachines), opportunities and challenges using artificial intelligence in ADME/Tox in drug development, commercialization and regulatory perspectives, ethics in AI, and more. This book will be useful to academic and industrial researchers interested in drug delivery, chemical biology, computational chemistry, medicinal chemistry and bioinformatics. The massive time and costs investments in drug research and development necessitate application of more innovative techniques and smart strategies.