Over the past century, new farming methods, feed additives, and social and economic structures have radically transformed agriculture around the globe, often at the expense of human health. In Chickenizing Farms and Food, Ellen K. Silbergeld reveals the unsafe world of chickenization-big agriculture's top-down, contract-based factory farming system-and its negative consequences for workers, consumers, and the environment. Drawing on her deep knowledge of and experience in environmental engineering and toxicology, Silbergeld examines the complex history of the modern industrial food animal production industry and describes the widespread effects of Arthur Perdue's remarkable agricultural innovations, which were so important that the US Department of Agriculture uses the term chickenization to cover the transformation of all farm animal production. Silbergeld tells the real story of how antibiotics were first introduced into animal feeds in the 1940s, which has led to the emergence of multi-drug-resistant pathogens, such as MRSA. Along the way, she talks with poultry growers, farmers, and slaughterhouse workers on the front lines of exposure, moving from the Chesapeake Bay peninsula that gave birth to the modern livestock and poultry industry to North Carolina, Brazil, and China. Arguing that the agricultural industry is in desperate need of reform, the book searches through the fog of illusion that obscures most of what has happened to agriculture in the twentieth century and untangles the history of how laws, regulations, and policies have stripped government agencies of the power to protect workers and consumers alike from occupational and food-borne hazards. Chickenizing Farms and Food also explores the limits of some popular alternatives to industrial farming, including organic production, nonmeat diets, locavorism, and small-scale agriculture. Silbergeld's provocative but pragmatic call to action is tempered by real challenges: how can we ensure a safe and accessible food system that can feed everyone, including consumers in developing countries with new tastes for western diets, without hurting workers, sickening consumers, and undermining some of our most powerful medicines?

"Warning. Smoking Kills!" It also corrupts law enforcement officials and eviscerates state institutions. It devours politicians, professionals, business people and ordinary workers in the chase for big bucks and the battle for a slice of an ever-shrinking cigarette market.

Join one of South Africa's former tax sleuths, Johann van Loggerenberg, in a wild ride through the double-dealing world of tobacco's colourful characters and ruthless corporates. Meet the femme fatales, mavericks, mercenaries and grandmasters, and learn how the crime-busting unit led by van Loggerenberg at SARS and its "Project Honey Badger" became a victim of war between industry players and a high-stakes political game driven by state capture.

This is the tale of a few good men and women who dared to try to hold to account a billion-dollar international industry rife with private spy networks, tax evasion, collusion and corruption - ultimately at great cost to themselves and South Africa.

This book examines patent law and policy in biotechnology across the full lifecycle of the patent, focusing on the patent bargain and the public interest. It considers the central issues of how to strike an effective balance of rights, and whether public interest is adequately safeguarded - two issues that are particularly important in areas of rapidly emerging technology. Expert contributors are brought together to explore patent eligibility in biotechnology, focusing on the fields of precision medicine, biofabrication and non-invasive prenatal testing. Chapters also explore the construction and coherence of exceptions to patentability,an examination of FRAND licensing in the context of the internet of medical things, and the possibility of using licensing to encourage or ensure the ethical use of patented technologies. With its carefully constructed analysis, this book will be an excellent resource for academic researchers, and students, in the fields of biotechnology law, pharmaceutical law and intellectual property law. It will also be useful for legal practitioners and policymakers, as well as charitable bodies and non-governmental organisations.

Environmental Fate and Safety Management of Agrochemicals discusses residue analysis, environmental fate and safety management, environmental risk assessment, metabolism, resistance and management, and advances in formulation and application technology from the academic, government, and industry perspective.
Meaningful ecological and environmental risk assessment of pest control agents is possible only when accurate and credible metabolic and environmental fate data is available. The advent of affordable and sensitive liquid chromatography/mass spectrometry (LC/MS) has greatly increased our ability to detect environmentally relevant metabolites and degradation products following the application of these materials. Furthermore, ecological risk assessment and monitoring of pesticide resistance in field populations has become more feasible and cost effective by employing hig-hroughout molecular diagnostic techniques on the genetic leve3l and LC/MS techniques on the proteomic and meabolomic levels.
Efficient formulations and application technologies have greatly reduced the amount of materials that are required to achieve effective pest control and hence reduce their ecological and environmental impacts. Controlled release, stabilization and dispersion technologies have provided the pest manager with new tools that allow them to use necessary pest control options in "best management strategies."

Large-scale adverse health and developmental outcomes related to tobacco affect millions of people across the world, raising serious questions from a human rights perspective. In response to this crisis, this timely book provides a comprehensive analysis of the promotion and enforcement of human rights protection in tobacco control law and policy at international, regional, and domestic levels. This thought-provoking book offers significant new insights to the topic, laying the foundations for a human rights based approach to tobacco control. Addressing the function of law as a tool to help combat one of the major public health challenges facing society, contributions by global scholars rebut human rights claims presented by the tobacco industry. Emphasis is instead placed upon the human rights of vulnerable individuals, children in particular, as a result of smoking and exposure to second-hand smoke. Illustrating ways in which the right to health can be advanced with regards to tobacco control, smoking and the use of e-cigarettes, this important book will be a vital resource for human rights and health law scholars and practitioners as well as policy makers in public health law. Contributors include: D. Barrett, D. Beyleveld, O.A. Cabrera, A. Constantin A. Garde, M.E. Gispen, L. Gruszczynski, J. Hannah, S. Karjalainen, L. Lane, S. Lierman, A.L. McCarthy, A. Mitchell, S. Negri, O. Nnamuchi, M. Roberts, A. Schmidt, M. Sormunen, A. Taylor, B. Toebes, M. van Westendorp, Y. Zhang

A clear and lively account of the machinery, innovation and personalities that have shaped the industry that provides the all-essential daily bread. Indispensible for anyone with an interest in industrial history. There is a wealth of literature on the traditional flour milling industry, much of it concerned with the charms of rural settings and ancient crafts, whereas the history of the dramatic changes in milling methods from the 1870s onwards has been somewhat neglected. Written by Glyn Jones, engineer and lecturer in technology, `The Millers' sets out to redress the balance and tells the story of the transformation of the flour milling industry by men of vision with enterprise and engineering skill, from the first experiments with roller mills before 1880 to the sleek, automated flour mills operating at the end of the twentieth century. It is a story of technological endeavour and industrial success. The innovations were revolutionary, with roller mills, purifiers and a variety of sifting and sorting machines replacing millstones and crude sieving equipment. Change was propelled by an increasing demand for white bread, and whiter flour could be produced by roller milling of hard foreign wheats, whereas traditional millstone methods were not suitable for the production of large quantities of branless flour. Henry Simon, who became the pioneering leader of the new field of milling engineering, installed his first roller plant in Manchester in 1878; by 1887 mills on the Simon system could produce enough flour to meet the requirements of 11 million people. The mass production of flour for our daily bread began in earnest. From 1904, the most forceful innovator among British millers was Joseph Rank, who commissioned Henry Simon Ltd to supply new plants at the main ports of Hull, London, Cardiff and Liverpool. The roles played by the other leading millers, many of which are still household names, are also included in this account. Despite the hugely impressive and far-reaching technological advances made by British millers and milling engineers, they have not received the credit they deserve. In truth, they replaced the traditional, basic form of the industry rapidly and effectively, and their inventions transformed milling in Britain and further afield. `The Millers' describes, in a clear and lively way, not only the changes in machinery and processing and the effects on the traditional industry, but the personalities who shaped the trade and the companies they ran, and the myths and legends which have surrounded them. Modern mills, rooted in British innovation and enterprise, are impressive in appearance and striking inside, with machinery that looks smart and is automatically controlled, processing wheat for a range of attractive foods and for the still essential daily bread.

This timely book discusses the application of the EU competition rules to pharmaceuticals, covering the prohibitions on anticompetitive agreements and abuse of dominance, and merger control. The author team comprises academic experts and private practitioners who analyse recent case law at both EU (and UK) and Member State levels - in the context of current issues and future trends, including those related to COVID-19 - and examine the impact of competition law on the behaviour of the pharmaceutical industry. The book carefully considers the balance between competition and innovation, as well as between competition and regulation. It concludes that competition and regulation are not alternatives, but complementary, and that novel ways of taking into account risk and real innovation through competition assessments have been developed. Integrating an overview of competition law, IP law and pharmaceutical regulation, this book will be an ideal read for scholars and graduate students, as well as private and public practitioners interested in pharmaceutical and European law.

Now with a new afterword covering the months-long landmark trials of Elizabeth Holmes and Sunny Balwani. ‘I couldn’t put down this thriller . . . the perfect book to read by the fire this winter.’ Bill Gates Winner of the Financial Times/McKinsey Business Book of the Year Award 2018 The riveting true story of the breathtaking rise and shocking collapse of Theranos, the multibillion-dollar biotech startup founded by Elizabeth Holmes, by the prize-winning journalist who first broke the story and pursued it to the end, despite pressure from its charismatic CEO and threats by her lawyers. In 2014, Theranos founder and CEO Elizabeth Holmes was widely seen as the female Steve Jobs: a brilliant Stanford dropout whose startup ‘unicorn’ promised to revolutionize the medical industry with a machine that would make blood testing significantly faster and easier. Backed by investors such as Larry Ellison and Tim Draper, Theranos sold shares in a fundraising round that valued the company at more than $9 billion, putting Holmes’s worth at an estimated $4.7 billion. There was just one problem: the technology didn’t work. In Bad Blood, John Carreyrou tells the riveting story of the biggest corporate fraud since Enron, a tale of ambition and hubris set amid the bold promises of Silicon Valley. ‘Chilling . . . Reads like a West Coast version of All the President’s Men.’ New York Times Book Review

Winner of the 2021 Rachel Carson Environmental Book Award Winner of the 2021 Maine Literary Award for Nonfiction Finalist for the 2020 National Book Critics John Leonard Prize for Best First Book Finalist for the 2021 New England Society Book Award Finalist for the 2021 New England Independent Booksellers Association Award A New York Times Editors' Choice and Chicago Tribune top book for 2020 "Mill Town is the book of a lifetime; a deep-drilling, quick-moving, heartbreaking story. Scathing and tender, it lifts often into poetry, but comes down hard when it must. Through it all runs the river: sluggish, ancient, dangerous, freighted with America's sins." --Robert Macfarlane, author of Underland Kerri Arsenault grew up in the small, rural town of Mexico, Maine, where for over 100 years the community orbited around a paper mill that provided jobs for nearly everyone in town, including three generations of her family. Kerri had a happy childhood, but years after she moved away, she realized the price she paid for that childhood. The price everyone paid. The mill, while providing the social and economic cohesion for the community, also contributed to its demise. Mill Town is a book of narrative nonfiction, investigative memoir, and cultural criticism that illuminates the rise and collapse of the working-class, the hazards of loving and leaving home, and the ambiguous nature of toxics and disease with the central question; Who or what are we willing to sacrifice for our own survival?

This is the story of how private foreign enterprise in the form of Swedish Lloyd and Swedish America Line, who formed a British company called 'Hoverlloyd', galvanised the British Government in to supporting this new concept in transport through the formation of a British Rail subsidiary called 'Seaspeed'. It is a story, told by those who were there, of how young adventurous men and women, most of whom were in their twenties and early thirties, took on the exciting challenge of getting an operation, in which they all believed had a great future, off the ground. It tells of the difficulties and near disasters, through lack of experience, that nearly wrote off the industry in the early days; the clashes of cultures between the free enterprise and Government operations; and why, after so much early promise, the great adventure with the giant car and passenger carrying hovercraft came to an end. The story begins with the history of Saunders Roe and their involvement as a result of the discovery by Christopher Cockerell in 1953 that big weights could be supported on a cushion of low pressure air and that the concept could be practically applied. Much has already been written about Christopher Cockerell, later Sir Christopher, and the development of the hovercraft by Saunders Roe, as well as the hovercraft industry to the present day. Those relevant parts showing the frustrations and disappointments they too suffered are repeated in this book, together with new material that has come to light, to provide a comprehensive narrative of the hovercraft industry and the giant SR.N4 cross-Channel operations.

This is the story of how private foreign enterprise in the form of Swedish Lloyd and Swedish America Line, who formed a British company called 'Hoverlloyd', galvanised the British Government in to supporting this new concept in transport through the formation of a British Rail subsidiary called 'Seaspeed'. It is a story, told by those who were there, of how young adventurous men and women, most of whom were in their twenties and early thirties, took on the exciting challenge of getting an operation, in which they all believed had a great future, off the ground. It tells of the difficulties and near disasters, through lack of experience, that nearly wrote off the industry in the early days; the clashes of cultures between the free enterprise and Government operations; and why, after so much early promise, the great adventure with the giant car and passenger carrying hovercraft came to an end. The story begins with the history of Saunders Roe and their involvement as a result of the discovery by Christopher Cockerell in 1953 that big weights could be supported on a cushion of low pressure air and that the concept could be practically applied. Much has already been written about Christopher Cockerell, later Sir Christopher, and the development of the hovercraft by Saunders Roe, as well as the hovercraft industry to the present day. Those relevant parts showing the frustrations and disappointments they too suffered are repeated in this book, together with new material that has come to light, to provide a comprehensive narrative of the hovercraft industry and the giant SR.N4 cross-Channel operations.

Soon to be the major motion picture Pain Hustlers starring Emily Blunt and Chris Evans streaming on Netflix ‘A pacey crime caper set against the backdrop of the opioid crisis . . . When I tell you that reading The Hard Sell is like watching a Scorsese film, you will assume I am exaggerating. Pick it up and tell me I’m wrong.' - Patrick Radden Keefe, The New York Times In the early 2000s, John Kapoor had already amassed a small fortune in pharmaceuticals when he founded Insys Therapeutics. A boom time for painkillers, he had developed a novel formulation of fentanyl, the most potent opioid on the market. Kapoor, a brilliant scientist with relentless business instincts, was eager to make the most of his innovation. But there was a problem: the drug was approved only for cancer patients in dire condition. So he recruited an avaricious team, who employed a variety of deceptive techniques, from falsifying patient records to deceiving insurance companies. Insys became a Wall Street sensation. That is, until insiders reached their breaking point and blew the whistle, sparking a sprawling investigation in the government’s fight to hold the drug industry accountable in the spread of addictive opioids. With colourful characters and true suspense, The Hard Sell lays bare the pharma playbook. Evan Hughes offers a bracing look not just at Insys, but at how opioids are sold at the point they first enter the national bloodstream – in the doctor’s office . . .

This incisive volume of the Elgar Encyclopedia of Environmental Law offers a broad analysis of the foundations, main concepts, and substantive and procedural requirements of selected chemical law regimes as they pertain to the environment. Featuring contributions from more than 40 expert scholars and practitioners in the field, the volume focuses on chemical regulatory systems from representative jurisdictions, including the EU and the US, to provide a coherent overview of this expansive and often fragmented area of law. Divided into five thematic parts, the volume first examines the fundamental concepts of chemical law, addressing topics including risk assessment, nomenclature, environmental justice and animal testing. Entries then discuss types of chemicals and exposures, regulation of chemicals in products and manufacturing, and waste and contamination, as well as covering liability rules as they apply to chemicals. This volume will be an essential resource for scholars and students looking for a clear understanding of chemicals regulation and governance from environmental and public health perspectives at both national and international levels. Its insights into policy developments and liability issues will also be of interest to policymakers and practitioners.

"These case stories focus on an important event, mishap, management practice, or ethical question, and present important lessons to the reader. Their objective is to educate, inspire, motivate, challenge, and encourage food professionals to better understand food safety management and to help increase job effectiveness and productivity with ethics and integrity. Each case addresses its subject in terms of relevance and application to food safety and covers all types of risks (e.g., microbial, chemical, physical) associated with each step of the food chain. In an engaging format, the book provides an analysis of incidents or near misses. It highlights pitfalls in food safety management and provides key insight into the means of avoiding them. The book captures the real-life experience of food safety professionals around the world in very challenging situations, and invites the reader to reflect on and discuss the situations depicted. It is an essential reference for students and food professionals, including scientists, managers, trainers, food inspectors, public health officials, and more. Each of the 87 short cases includes a paragraph on "Discussion and key learnings", which will appeal equally to educators, students and working professionals in this field."

Biotechnology is a field that inspires complex legal and ethical debates on an international scale. Taking a fresh approach to the subject, Matthias Herdegen provides a comprehensive assessment of the regulation of biotechnology processes and products from an international and comparative perspective. Herdegen explores how regulatory approaches to controversial issues such as: stem cell research and cloning and gene therapy differ across jurisdictions due to conflicting values and risk perceptions. The book goes on to examine how international regulatory instruments aim to address these conflicting perspectives and provide judgments based on broad international consensus. Chapters explore the interaction between biotechnology and different fields of law including: human rights, intellectual property, trade law and environmental law. In doing so, a number of complex issues are raised such as the need to balance commercial interests with socio-cultural considerations and the need to ensure respect for human dignity in the pursuit of biomedical research. Providing a concise and accessible guide to a complex field of international law, this book will be of great value to those researching the law and regulation of biotechnology, biomedicine and biodiversity both within the EU and on an international scale. The book will also be a useful resource for practicing lawyers as it includes sources from a diverse range of legal systems and analyses relevant decisions by international adjudicatory bodies.

A "sharp and entertaining" (The Wall Street Journal) exploration of fashion through the ages that asks what our clothing reveals about ourselves and our society. Dress codes are as old as clothing itself. For centuries, clothing has been a wearable status symbol; fashion, a weapon in struggles for social change; and dress codes, a way to maintain political control. Merchants dressing like princes and butchers' wives wearing gem-encrusted crowns were public enemies in medieval societies structured by social hierarchy and defined by spectacle. In Tudor England, silk, velvet, and fur were reserved for the nobility, and ballooning pants called "trunk hose" could be considered a menace to good order. The Renaissance-era Florentine patriarch Cosimo de Medici captured the power of fashion and dress codes when he remarked, "One can make a gentleman from two yards of red cloth." Dress codes evolved along with the social and political ideals of the day, but they always reflected struggles for power and status. In the 1700s, South Carolina's "Negro Act" made it illegal for Black people to dress "above their condition." In the 1920s, the bobbed hair and form-fitting dresses worn by free-spirited flappers were banned in workplaces throughout the United States, and in the 1940s, the baggy zoot suits favored by Black and Latino men caused riots in cities from coast to coast. Even in today's more informal world, dress codes still determine what we wear, when we wear it--and what our clothing means. People lose their jobs for wearing braided hair, long fingernails, large earrings, beards, and tattoos or refusing to wear a suit and tie or make-up and high heels. In some cities, wearing sagging pants is a crime. And even when there are no written rules, implicit dress codes still influence opportunities and social mobility. Silicon Valley CEOs wear t-shirts and flip-flops, setting the tone for an entire industry: women wearing fashionable dresses or high heels face ridicule in the tech world, and some venture capitalists refuse to invest in any company run by someone wearing a suit. In Dress Codes, law professor and cultural critic Richard Thompson Ford presents a "deeply informative and entertaining" (The New York Times Book Review) history of the laws of fashion from the middle ages to the present day, a walk down history's red carpet to uncover and examine the canons, mores, and customs of clothing--rules that we often take for granted. After reading Dress Codes, you'll never think of fashion as superficial again--and getting dressed will never be the same.

IN "THE ANTIDOTE," Barry Werth draws upon unprecedented inside reporting spanning more than two decades to provide a groundbreaking closeup of the upstart pharmaceutical company Vertex and the ferocious but indispensable world of Big Pharma that it inhabits.
In 1989, the charismatic Joshua Boger left Merck, then America's most admired business, to found a drug company that would challenge industry giants and transform health care. Werth described the company's tumultuous early days during the AIDS crisis in "The Billion-Dollar Molecule," a celebrated classic of science and business journalism. Now he returns to tell a riveting story of Vertex's bold endurance and eventual success.
The $325 billion-a-year pharmaceutical business is America's toughest and one of its most profitable. It's riskier and more rigorous at just about every stage than any other business, from the towering biological uncertainties inherent in its mission to treat disease; to the 30-to-1 failure rate in bringing out a successful medicine even after a molecule clears all the hurdles to get to human testing; to the multibillion-dollar cost of ramping up a successful product; to operating in the world's most regulated industry, matched only by nuclear power.
Werth captures the full scope of Vertex's twentyfive- year drive to deliver breakthrough medicines. At a time when America struggles to maintain its innovative edge, "The Antidote" is a powerful inside look at one of the most intriguing and important business stories of recent decades.

Presenting detailed analysis of the industrialization and commercialization of pharmaceutical patents in China, this timely book explores a range of related topics including a comparison of the ideal and existing state of the pharmaceutical market and patent industrialization. It argues that the core purpose of the industrialization of pharmaceutical patents is to promote the development of the local pharmaceutical industry whist also protecting society's right to safe and effective medication. Chapters examine the special application issues of patent law in relation to the field of pharmaceuticals, compare the Chinese and American legal systems and their approach to pharmaceutical patents, and provide in depth political and legal analysis of the industry. James Hou suggests methods by which the Chinese legal system can seek to improve its governance of pharmaceutical patents and balance the conflicts of interest arising between new drug developers, established drug manufacturers and the end users. Featuring comprehensive coverage of patents in the Chinese pharmaceutical industry, this book will be a key resource for scholars and students of commercial, pharmaceutical and intellectual property law, whilst also being of interest to industry talents discovering the potential of their own innovations.

We may be standing at the precipice of a revolution in propulsion not seen since the internal combustion engine replaced the horse and buggy. The proliferation of electric cars will change the daily lives of motorists, boost some regional economies and hurt others, reduce oil insecurity but create new insecurities about raw materials, and impact urban air quality and climate change. If you want to understand how quickly the transition is likely to occur, and the factors shaping the pace of the transition, this book delivers with a candid, illuminating style. The invention of the lithium-ion battery and its adaptation to the auto sector set the stage for the exciting proliferation of electric cars, beginning with California and Norway. This book focuses on the period from the oil crises of the 1970s to the present, tracing the development of this entirely new industry and its critical supply chain. John Graham delves into the major societal concerns, economic rationales, governmental policies and corporate strategies. He emphasizes that consumer concerns slowed the pace of the transition while spurring more innovation and new policies to persuade reluctant consumers. And he explains why the transition is now occurring much faster in China and Europe than in Japan and the United States. More broadly, the book tells the story of many successes and failures in public policy, technological innovation and corporate strategy. This book provides an in-depth understanding of how people on every continent in the world are contributing to the new electric-vehicle industry, including the raw materials, battery components, electric motors and charging stations. Faculty, students and researchers will appreciate the integrated treatment of the technical, economic, political and international issues. For the practitioner in industry, government and civil society, the book is an engaging look at the roles of key decision makers and organizations, both those favoring electric cars and those opposed.

Blockchain has potential to revolutionize how manufacturers design, engineer, make and scale their products. Blockchain is gradually proving to be an effective "middleware" solution for enabling seamless interoperability within complex supply chains. Due to its technological nature, blockchain enables secure, transparent and fast data exchanges as well as allowing for the creation of immutable records databases The main advantage of Blockchain in Manufacturing Industries is product traceability, supply chain transparency, compliance monitoring, and auditability. Moreover, leveraging blockchain technology into a manufacturing enterprise can enhance its security and reduce the rates of systematic failures. So, blockchain is now used in various sectors of the manufacturing industry, such as automotive, aerospace, defense, pharmaceutical, consumer electronics, textile, food and beverages, and more. Hence, Blockchain should be seen as an investment in future-readiness and customer-centricity, not as an experimental technology - because, the evidence is overwhelming. This book will explore the strengths of Blockchain adaptation in Manufacturing Industries and Logistics Management, cover different use cases of Blockchain Technology for Manufacturing Industries and Logistics Management, and will discuss the role, impact and challenges of adopting Blockchain in Manufacturing industries and Logistics Management. The chapters will also provide the current open issues and future research trends of Blockchain, especially for Manufacturing Industries and Logistics, and will encapsulate quantitative and qualitative research for a wide spectrum of readers of the book.