The fourth industrial revolution is having a major impact on industry and societies primarily because of what has been called its raw material: data. New technologies are allowing hyper-connection on a global scale, not only between people, but also between people and machines and, in the case of the Internet of Things, even amongst machines themselves. This book offers a critical reflection on the meaning and expected consequences of the fourth industrial revolution, with a particular focus on the advent of digital globalisation and its implications for industrial policy. Industrial revolutions are considered not only in terms of technological progress, but also in the context of the changing relationship between market and production dynamics, and the social and political conditions enabling the development of new technologies. Industrial Policy for the Manufacturing Revolution aims to increase our capacity to anticipate and adapt to the forthcoming structural changes. It outlines the type of industrial policy and strategies that are needed in this era of rapid transformation. The authors propose a 'comprehensive industrial policy' that considers the complexity of structural changes involving industry as well as institutions and social and education policies, in order to encourage the participation of all citizens in the development process. The book also features a concrete example of comprehensive industrial policy implementation at the regional level. This stimulating and thoughtful book makes the case that industrial policies are more vital than ever, particularly now as the economy undergoes a technological revolution. It will be required reading for all those interested in industrial economics and policy, business and technology.

Vaccine development is a complex and time consuming process that differs from the development of conventional pharmaceuticals. Primarily, vaccines are intended for use in healthy individuals as a preventative measure, requiring a long and rigorous process of research and many years of testing and development prior to clinical trials and regulatory approval. The average time for the development of vaccines to clinical is 12 to 15 years. Vaccine Development: From Concept to Clinic is a detailed overview of the development of new vaccines, covering the entire process and addresses all classes of vaccines from a processing, development and regulatory viewpoint. Utilising successful case studies the book will provide insight to the issues scientists face when producing a vaccine, the steps involved and will serve as an ideal reference tool regarding state-of-the-art vaccine development. This book is an ideal companion for any researchers working in vaccine discovery and development or with an interest in the field.

Now with a new afterword covering the months-long landmark trials of Elizabeth Holmes and Sunny Balwani. ‘I couldn’t put down this thriller . . . the perfect book to read by the fire this winter.’ Bill Gates Winner of the Financial Times/McKinsey Business Book of the Year Award 2018 The riveting true story of the breathtaking rise and shocking collapse of Theranos, the multibillion-dollar biotech startup founded by Elizabeth Holmes, by the prize-winning journalist who first broke the story and pursued it to the end, despite pressure from its charismatic CEO and threats by her lawyers. In 2014, Theranos founder and CEO Elizabeth Holmes was widely seen as the female Steve Jobs: a brilliant Stanford dropout whose startup ‘unicorn’ promised to revolutionize the medical industry with a machine that would make blood testing significantly faster and easier. Backed by investors such as Larry Ellison and Tim Draper, Theranos sold shares in a fundraising round that valued the company at more than $9 billion, putting Holmes’s worth at an estimated $4.7 billion. There was just one problem: the technology didn’t work. In Bad Blood, John Carreyrou tells the riveting story of the biggest corporate fraud since Enron, a tale of ambition and hubris set amid the bold promises of Silicon Valley. ‘Chilling . . . Reads like a West Coast version of All the President’s Men.’ New York Times Book Review

The fourth industrial revolution is having a major impact on industry and societies primarily because of what has been called its raw material: data. New technologies are allowing hyper-connection on a global scale, not only between people, but also between people and machines and, in the case of the Internet of Things, even amongst machines themselves. This book offers a critical reflection on the meaning and expected consequences of the fourth industrial revolution, with a particular focus on the advent of digital globalisation and its implications for industrial policy. Industrial revolutions are considered not only in terms of technological progress, but also in the context of the changing relationship between market and production dynamics, and the social and political conditions enabling the development of new technologies. Industrial Policy for the Manufacturing Revolution aims to increase our capacity to anticipate and adapt to the forthcoming structural changes. It outlines the type of industrial policy and strategies that are needed in this era of rapid transformation. The authors propose a 'comprehensive industrial policy' that considers the complexity of structural changes involving industry as well as institutions and social and education policies, in order to encourage the participation of all citizens in the development process. The book also features a concrete example of comprehensive industrial policy implementation at the regional level. This stimulating and thoughtful book makes the case that industrial policies are more vital than ever, particularly now as the economy undergoes a technological revolution. It will be required reading for all those interested in industrial economics and policy, business and technology.

The inspiration behind the Netflix tv series Painkillers, starring Uzo Aduba and Matthew Broderick THE SUNDAY TIMES BESTSELLER Now on BBC Radio 4 'Book of the Week' Winner of the 2021 Baillie Gifford Prize for Non-Fiction Shortlisted for the 2021 Financial Times/McKinsey Business Book of the Year Award One of Barack Obama's Favorite Books of 2021 Shortlisted for the Crime Writers' Association Gold Dagger for Non-Fiction The gripping and shocking story of three generations of the Sackler family and their roles in the stories of Valium, OxyContin and the opioid crisis. 'One of those authors I will always read, no matter what the subject matter, which is why I gobbled up Empire of Pain . . . a masterclass in compelling narrative nonfiction.' - Elizabeth Day, The Guardian '30 Best Summer Reads' 'You feel almost guilty for enjoying it so much' - The Times The Sackler name adorns the walls of many storied institutions - Harvard; the Metropolitan Museum of Art; Oxford; the Louvre. They are one of the richest families in the world, known for their lavish donations in the arts and the sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing Oxycontin, a blockbuster painkiller that was a catalyst for the opioid crisis - an international epidemic of drug addiction which has killed nearly half a million people. In this masterpiece of narrative reporting and writing, award-winning journalist and host of the Wind of Change podcast Patrick Radden Keefe exhaustively documents the jaw-dropping and ferociously compelling reality. Empire of Pain is the story of a dynasty: a parable of twenty-first-century greed.

As technology advances, it is imperative to stay current in the newest developments made within the engineering industry and within material sciences. Trends in manufacturing such as 3D printing, casting, welding, surface modification, computer numerical control (CNC), non-traditional, Industry 4.0 ergonomics, and hybrid machining methods must be closely examined to utilize these important resources for the betterment of society. Advanced Manufacturing Techniques for Engineering and Engineered Materials provides a unified and complete overview about the recent and emerging trends, developments, and associated technology with scope for the commercialization of techniques specific to manufacturing materials. This book also reviews the various machining methods for difficult-to-cut materials and novel materials including matrix composites. Covering topics such as agro-waste, conventional machining, and material performance, this book is an essential resource for researchers, engineers, technologists, students and professors of higher education, industry workers, entrepreneurs, researchers, and academicians.