In this thoroughly updated second edition, Matthias Herdegen provides a comprehensive and contemporary assessment of the regulation of biotechnology processes and products from an international and comparative perspective, complete with analysis of intricate legal and ethical debates. Considering recent advances in biotechnology, this new edition explores how regulatory approaches to controversial issues such as stem cell research, cloning and gene therapy differ across jurisdictions due to conflicting values and risk perceptions. Reflecting on current developments, the book explores the interaction between biotechnology and different fields of law, including: human rights, intellectual property, trade law and environmental law. In doing so, Herdegen investigates complex concerns such as balancing commercial interests with socio-cultural considerations and ensuring respect for human dignity in the pursuit of biomedical research. Furthermore this new edition includes examination of recent developments in areas such as genome editing, biomedicine, COVID-19 vaccines, and patents on essentially biological products, with an entirely revised section on biobanks. Providing a concise and accessible guide to a complex field of international law, this book will be of great value to those researching the law and regulation of biotechnology, biomedicine and biodiversity both within the EU and at an international level. Practicing lawyers will also benefit from a diverse array of sources from a range of legal systems.

Faster, Higher, Farther chronicles a corporate scandal that rivals those at Enron and Lehman Brothers-one that will cost Volkswagen more than $22 billion in fines and settlements. Through meticulous reporting, New York Times correspondent Jack Ewing documents why VW felt compelled to install "defeat devices" in diesel vehicles that unlawfully lowered CO2 levels during emissions testing, and how the fraud was committed, covered up, and finally detected. Faster, Higher, Farther is a briskly written account of unrivaled corporate greed. Updated with the latest information and a new afterword by the author.

Discusses the clinical application of functional foods for the management of a wide range of chronic diseases Covers chronic diseases including Obesity, Arthritis, Cardiovascular Diseases, and Endocrinal and Hormonal Diseases, among others. Explores beneficial effects of nutraceuticals in chronic diseases *pending Vol 2 features

The emergence of platforms is a novel phenomenon impacting most industries, from products to services. Industry platforms such as Microsoft Windows or Google, embedded within industrial ecosystems, have redesigned our industrial landscapes, upset the balance of power between firms, fostered innovation and raised new questions on competition and innovation. Annabelle Gawer presents cutting-edge contributions from 24 top international scholars from 19 universities across Europe, the USA and Asia, from the disciplines of strategy, economics, innovation, organization studies and knowledge management. The novel insights assembled in this volume constitute a fundamental step towards an empirically based, nuanced understanding of the nature of platforms and the implications they hold for the evolution of industrial innovation. The book provides an overview of platforms and discusses governance, management, design and knowledge issues. With a multidisciplinary approach, this book will strongly appeal to academics and advanced students in management, innovation, strategy, economics and design. It will also prove an enlightening read for business managers in IT industries.

The 2022 edition of the Rules and Guidance for Pharmaceutical Distributors, the 'Green Guide', is the essential reference for all distributors, brokers of human medicines, importers and distributors of active substances in the UK.It provides you with the single authoritative source of European good distribution practices and UK guidance, information and UK legislation on these activities.The new 5th edition has been updated to incorporate changes made after the UK's exit from the European Union on the 31st January 2020.It also incorporates new guidance on pharmacovigilance for wholesalers, the naming of sites on a licence, self-inspection, and the responsible person for import.It brings together EU guidance on good distribution practice and the MHRA's expectations for compliance. There is also a new flowchart for the registration of handling active substances

The provision of food is undergoing radical transformations throughout the global community. Peter Oosterveer argues that, as a consequence, conventional national governmental regulations can no longer adequately respond to existing and emerging food risks and to environmental concerns. This book examines these challenges. Translating recent innovative thinking in the social sciences - as seen in the work of Manuel Castells and John Urry amongst others - to the world of food, this book reviews the challenges facing global food governance and the innovative regulatory arrangements that are being introduced by different governments, NGOs and private companies. The analysis includes case-studies on the European BSE crisis, GM-food regulation, salmon and shrimp farming and food labelling. The author highlights how contemporary governance arrangements also have to acknowledge increasing consumer demand for food produced with care for the environment, animal welfare and social justice. Developing and implementing adequate global food governance arrangements therefore demands the active involvement of private firms, consumers, and civil society organisations with national governments. Peter Oosterveer's book will appeal to scholars - postgraduate and above - involved in industrial organization, agricultural studies and environmental sciences as well as those with an interest in the globalisation and governance of this important and topical area.

It has been 100 years since the first airfield was established in the country town of Yeovil. Since 1915, aircraft have been designed, manufactured and tested at Westland, including the Lysander, used to transport British agents to Europe during the Second World War. In 1948 the company focused solely on helicopters and its aircraft have been sent all over the world since then, used in lifesaving with Air Ambulance and Search and Rescue and deployed in warfare such as Balkans, Iraq and Afghanistan. To celebrate the centenary of the UK's only major helicopter manufacturer, David Gibbings has collated an anthology of writings that retell Westland's history and its special relationship with Yeovil, which has rarely been quiet since the first aircraft took off from the airfield that now lies at its heart.

Was Keith Harris's Orville really named after the first-ever flyer? What exactly is a 'Spitfire'? Why did Richard Branson try to cross the Atlantic in a balloon when he owned an airline? These are the questions that fail to keep proper aeronautical historians awake - but no matter, From Wax Wings to Flying Drones is here to answer them. Chock-full of important stuff like planes, pilots and pioneers such as the Wright brothers, Amelia Earhart and that man off the telly who used to fly on Concorde, this is a book for everyone who's ever watched a plane in the sky and thought, 'I wonder what its registration is?'

This book provides an in-depth analysis of the processes of innovation found in industrial clusters. The authors focus particularly on the characteristics of innovation clusters and their operation in the food industry. This is revealed through novel case studies, detailed research on the dynamic cluster relationship between academia and industry, and the role of competencies, resources, interactions and leadership. The results reveal that innovation processes are significantly different from product development processes and that many failures of innovation can be explained by a lack of distinction between the two. The authors also offer informative insights on the interactions between different technologies, the convergence between technologies and consumers, and the manner in which these two elements are handled in the innovation process. They move on to identify three different phases of the innovation process and illustrate how the importance of cluster partners, competencies and management can vary at each stage. In addition, they highlight the importance of allowing innovations to grow and develop, and emphasise the fact that successful innovations cannot simply be 'assembled' from the necessary components. Entrepreneurs, R&D managers and academics working in the fields of innovation, technology management and industrial strategy will all value the in depth case-studies and rigorous analysis which adds a new and significant dimension to the many arguments surrounding cluster management.

Innovation in the Pharmaceutical Industry traces the discovery and development of drugs in Japan and the UK both historically and sociologically. It includes sixteen case studies of major pharmaceutical developments in the twentieth century, encompassing, amongst others, beta-blockers, beta-stimulants, inhaled steroids and histamine H2-antagonists. The book illustrates that the four stages of drug development - namely compound, application, organisational authorisation and market - are interactively shaped by heterogeneous actors and institutions. The book also identifies three different types of pharmaceutical development - paradigmatic innovation, application innovation and modification-based innovation, all with distinguishable features in the drug development process. Finally, several historical, structural and cultural factors influencing the shaping of medicines are revealed by the comparison between British and Japanese drug innovation. Addressing a number of practical implications for the promotion of the pharmaceutical industry, this book will be of enormous interest to students, researchers and academics specialising in science and technology, and the management of technology and innovation. Practitioners, managers, and policy planners within the pharmaceutical industry will also deem this book invaluable.

In this book, leading experts in the field examine the effects of the recent growth in concentration in the European food retailing sector. In particular, the book develops a number of buyer power propositions and builds on the previous work of several of the authors, to consider how the growth of large supermarket chains affects competition in food retailing. The authors outline the theoretical and policy analysis underpinning the work and assess evidence on the size and growth of supermarket chains across the EU. Whilst not entirely critical, they suggest that there is strong evidence in some countries that supermarkets use their buying power to impose unfair terms and conditions on suppliers, particularly affecting small suppliers. The authors use case studies, to provide an in-depth analysis of four European countries, namely France, Germany, Spain and the UK. The book ends with a discussion of policy issues against a backdrop of likely future trends in concentration in this area. Academics working in the areas of microeconomics and industrial economics as well as those involved in European competition policy more generally, such as lawyers, civil servants and consultancy groups, will find this volume enlightening.

'The astoundingly well reported and beautifully told story of the downfall of what was once a great American company. A must-read' Bethany McLean, bestselling author of The Smartest Guys in the Room 'Compelling and richly reported, Flying Blind is about so much more than the sad decline of Boeing and the tragic mistakes that led to the 737 Max disaster. It's also the urgent story of how the almighty profit motive supplanted a culture of engineering excellence in boardrooms across America' Brad Stone, bestselling author of The Everything Store The definitive exposé of how Boeing put profit before passengers, leading to the devastating loss of life in the 737 MAX crashes and the downfall of an American business giant In examining the history of the 737, Flying Blind explores how Boeing's new management degraded a highly-regarded plane with cost-focused mandates and skimped on testing in the race to match a competing plane from Airbus. How Boeing outsourced software work to poorly paid graduates in India and convinced the US Federal Aviation Authority to put the MAX into service without requiring pilots to undergo simulator training, and how ultimately these failures resulted in the deaths of 346 Boeing passengers. Framed around the 737 MAX crashes, Flying Blind is the definitive exposé that for the first time tells the larger, decades-long story of how a corrupt corporate culture paved the way for a cataclysm that cost lives. 'Vividly written and meticulously researched, Flying Blind is a story everyone - every consumer, every citizen, every worker in every industry - needs to read' Diana B. Henriques, New York Times bestselling author of The Wizard of Lies: Bernie Madoff and the Death of Trust 'A gripping narrative and required reading for anyone who wants to understand how one of America's mightiest corporations veered so badly off course' Sheelah Kolhatkar, New Yorker staff writer and bestselling author of Black Edge

* One of the first critiques of participatory design processes that are currently the fashion in design and business * highlights political, social and methodological obstacles when designers turn to design thinking, participation and "living labs" * uses global examples to introduce a more critical and post-colonial perspective on participation and social innovation throughout the book

Manufacturing has played a key role in the economic fortunes of the East and South Asian regions. This timely book analyses patterns of rapid catch-up and relative stagnation in the manufacturing sector and links these to economic growth in the region. Dr Timmer describes the manufacturing performance of five Asian countries since the 1960s: China, India, Indonesia, South Korea and Taiwan. Over this period Asian industrial development is placed in an international perspective by comparison with the world productivity leader, the USA. The author uses new empirical data to assess the degree of structural change in the manufacturing sector and its importance for productivity growth. He then discusses conditions for economic growth and catch up, and reviews the role of industrial and technology policies in the promotion of industrial development in Asia.

The fascinating story of a century-old automobile dynasty

Fiat is one of the world's largest automakers, but when it made headlines by grabbing control of a bankrupt Chrysler in 2009 it was unknown in the U.S. Fiat's against-all-odds swoop on Chrysler---masterminded by Sergio Marchionne, the Houdini-like manager who saved Fiat from its own near-collapse in 2005 - has made the automaker one of the most unlikely winners of the financial crisis. "Mondo Agnelli" is a new book that looks at the chain of unpredictable events triggered by the death of Gianni Agnelli in 2003. Gianni, the charismatic, silver-haired power broker and style icon, was the patriarch who had lead the company founded by his grandfather in 1899. But Gianni's own son had committed suicide. Without a mature heir, the dynasty and Fiat were rudderless. Backed by Gianni's closest advisors, his serious, shy, and determined grandson John plucked Marchionne from obscurity. Together, they saved the family company and, inadvertently, positioned Fiat as a global trailblazer when the global storm hit.A classic story of ingenuity and hard work, the book portrays a business dynasty that triumphed over adversity and family tragedy because of its own smarts, sweat, and ability to bend the rulesA an engaging tale for those interested in the stories behind the economic crash, the book contains never-before reported material about how Fiat succeeded in making Chrysler profitable where both Daimler AG and Cerberus, its previous owners, had failed.

A story for a wide audience, from car buffs, business readers, lovers of Italy, and anyone fascinated by the lifestyle of Europe's most glamorous industrial dynasty, this book tells the tale of how Fiat achieved the seemingly impossible -- turning around an American automotive icon everyone else had given up for dead.

Do environmental regulations harm international competitiveness? In answer to this question, this book focuses on the impact of regulatory policies on competitiveness and employment at the firm level. It investigates the trade-off between environmental regulations and competitiveness across countries and regions throughout Europe, using the food processing industry as a case study.The authors compare and contrast the experiences of similar firms across Europe to examine the different costs firms face in applying environmental regulations and the different levels of competitiveness they achieve as a result. The investigation includes a detailed and thorough comparison of the European food processing industries using 67 company case studies. The results show that firms can achieve national or international levels of competitiveness even when they face a relatively unfavourable level of regulatory costs. These important findings will almost certainly have general application to small and medium sized firms in other industries. This book will be welcomed by policymakers, practitioners, researchers and academics interested in industrial economics, environmental management and environmental economics.

'This book represents a major contribution to our thinking about modern manufacturing industries - and is not just timely, it is long overdue! The authors have done an outstanding job in bringing to bear a range of multi-disciplinary perspectives on a domain which all too often suffers from rather narrow disciplinary analyses. Ranging from engineering to social science and drawing on examples from the US, Europe and Asia, the book provides not only a wealth of fact and illustration but a rich landscape to inform those charged with industrial policy and manufacturing strategies.' - From the foreword by Sir Mike Gregory, University of Cambridge, UK The Handbook of Manufacturing Industries in the World Economy provides a critical and multi-disciplinary state-of-the-art review and analysis of current manufacturing processes, practices and policies. Expanding our knowledge and understanding of production and innovation, this volume demonstrates that manufacturing continues to matter in the world economy. The contributors, including scholars ranging from engineering to policy to economic geography, cover manufacturing policy and the revival of the industrial base in the US, UK and Canada, and engage national and regional strategies for implementing advanced manufacturing policies. Questions of economic resilience in the wake of the recent recession are asked, and industry and firm case studies are utilised in an international comparative context. Applying a wide range of international cases from the US, EU, Australia and Asia, this approach allows readers to view transformations in production systems and processes across sectors, technologies and industries. Students, scholars and policymakers in the fields of public policy, economic geography, city and regional planning, and business and management will find this collection invaluable in understanding how firms and industries adapt, through dynamic and design-driven strategies, to produce for established and emerging markets. Contributors: M.A. Brown, J.R. Bryson, S. Christopherson, J. Clark, M. Cowell, M. Doussard, D.M. Drake, C.G. Drury, A. Dugenske, M. Feldman, P.L. Forrester, C. Gibson, P.V. Hall, Y. Hansen, C. Harris, P. Jalette, R.V. Kalafsky, W.C. Kessler, G. Kim, D.F. Kogler, L. Lanahan, F. Livesey, N.J. Lowe, L. McCormick, R. Mulhall, S. Ock Park, P. Pavlinek, J. Provo, M. Ronayne, G. Schrock, C.D.Treado, V. Vanchan, S. Walcott, B. Wang, M. Ward, A. Warren, S. Weller, L. Winther, L. Wolf-Powers

Global manufacturing has been altered by the emergence of a new approach to production which differs radically from the principles of mass production. This approach has been characterised by successful manufacturers in Asia and the West who have engaged in a continuous process to improve quality, process productivity and cost performance. The authors of Beyond Quality argue that many of the methods used by these new firms are equally suitable for manufacturers in developing countries and the transition economies of eastern and Central Europe. Using case study material from Latin America, Africa and Central Europe, the authors demonstrate that it is the skill and organization of people - rather than sophisticated equipment - which determines growth in productivity and product quality. These new forms of improvement are not dependent on economies of scale and so provide small producers with the flexibility to compete effectively against mass producers.

This book constitutes a fascinating and in-depth analysis of the significance of the requirement of industrial application within gene patenting and how this influences innovation in Europe and the US. The author addresses an area normally overlooked in biotechnology patenting due to the predominance of the ethical debate and, in doing so, produces a unique approach to dealing with concerns in this field. Patenting Genes: The Requirement of Industrial Application is the result of extensive research into the legal history of the industrial application requirement as well as exploration of the broad range of decisions on DNA patentability. This requirement has taken a prominent role within DNA patenting decisions in Europe since the 1998 Biotech Directive, which Dr Diaz Pozo argues has worked efficiently to control claims to human gene sequences and encouraged progress in genetic research. A broad selection of decisions on the patentability of DNA in both European Union and US courts is discussed, emphasizing the mirroring of the European approach in US cases. Academics and students of patent law and biotechnology innovation, as well as policy formulators, will find this book of great interest and value. Activists and practitioners interested in the patentability of human gene inventions in Europe and the US will also benefit from this original work.

The highly competitive world of retail branding and brand packaging is evident in the increasing demand for creating unique, eye-catching and recognisable clothing packaging designs. Designers continue to focus their talent by leveraging striking visual devices into an internal and external messaging system via the product's packaging design, which acts as a portable and extendable marketing tool. This superbly designed book showcases innovative, custom-packaging designs across a range of products, including footwear, clothing and apparel, fashion products, and more. Fashion Packaging Now presents in highly illustrated, full-colour detail how the brand connects with the item and with the packaging itself, and offers unique insight on individual project design production strategies. The case studies are modern, contemporary examples, which also feature many well-known brands, such as Adidas, Nike, and Puma. This book will be a source of inspiration for design aficionados, advertising and merchandise managers, students, brand and retail managers, and educators in the product design and graphic design fields.

This is the first textbook designed to teach statistics to students in aviation courses. All examples and exercises are grounded in an aviation context, including flight instruction, air traffic control, airport management, and human factors. Structured in six parts, theiscovers the key foundational topics relative to descriptive and inferential statistics, including hypothesis testing, confidence intervals, z and t tests, correlation, regression, ANOVA, and chi-square. In addition, this book promotes both procedural knowledge and conceptual understanding. Detailed, guided examples are presented from the perspective of conducting a research study. Each analysis technique is clearly explained, enabling readers to understand, carry out, and report results correctly. Students are further supported by a range of pedagogical features in each chapter, including objectives, a summary, and a vocabulary check. Digital supplements comprise downloadable data sets and short video lectures explaining key concepts. Instructors also have access to PPT slides and an instructor’s manual that consists of a test bank with multiple choice exams, exercises with data sets, and solutions. This is the ideal statistics textbook for aviation courses globally, especially in aviation statistics, research methods in aviation, human factors, and related areas.

J.J. Pizzuto's Fabric Science Swatch Kit, 12th Edition reinforces the study of textiles for students in courses such as Fashion Design, Fashion Business, Merchandising, Fashion Retailing, Interior Design, Textile Surface Design, Textile and Apparel Product Development, and Textile Production Management. The kit contains 114 (2"x 3") fabric samples, a fabric key, 32 special assignments, heavy-weight sample sheets to mount and analyze fabrics, and a pick glass--all contained in a three-ring binder. The swatches are organized in the order in which they are covered in the text: fibers, yarns, weaves, knits, dyeing, printing, and finishes. Swatches represent the types of fabrics currently available to fashion and interior designers in the field, making this resource an excellent addition to any professional library. Key Features Include -The text contains instructions and video tutorials that take students through the process of assembling their swatch kit and using a pick glass. -A Fabric Key identifies the swatches by number and fabric name, description, and fiber content. -Assignments are designed to reinforce the text and classroom lectures and have been developed by FIT instructors to broaden students' understanding of key concepts in textiles through hands-on labs and problem solving activities. -Students will successfully develop keen observation, analysis, and report writing skills. -J.J. Pizzuto's Fabric Science Swatch Kit is an ideal companion to J.J. Pizzuto's Fabric Science, 12th Edition (ISBN 9781501367878, available as a separate purchase) or can also be used alone or in conjunction with any textiles textbook. Fabric Science Swatch Kit STUDIO Resources Include -Watch videos with step-by-step demonstrations on how to compile the swatch kit Instructor's Resources -Instructor's Swatch Set including 7" x 12" samples of each fabric (ISBN 9781501368059) -Instructor's Guide provides specific information about each of the swatches in the Swatch Kit, special assignments, questions (with answers), and instructional comments -PowerPoint (R) presentations include full-color images from the book and provide a framework for lecture and discussion