Intracardiac Echocardiography is the first echocardiographic textbook of its kind to specifically cover ICE. Discussing all aspects of intracardiac ultrasound, it allows readers to perfect ICE image acquisition and helps to guide interpretation of this information during interventional and electrophysiologic procedures.

Unique and informative, the text explores:

• introductory echo physics
• currently available intracardiac ultrasound systems
• basic image acquisition
• the role of ICE in both the interventional and electrophysiology laboratory, as well as in the diagnostic setting.

Featuring expert commentary by leaders in the field, the book also includes high quality echocardiographic images illustrating how ICE is used in a wide variety of procedures such as transseptal catheterization, PFO and ASD closure, atrial fibrillation ablation procedures, and many others.

2021 marks the 50th anniversary of x-ray computed tomography (CT). Over the years, CT has experienced tremendous technological development, driven mainly by clinical needs but also by technology advancements in other fields. Six years after the third edition of Computed Tomography, this fourth edition captures the most recent advances in technology and clinical applications. New to this edition are descriptions of artificial intelligence, machine learning, and deep learning, and their application to image reconstruction, protocol optimization, and workflow. A new chapter covers the principles and advances in dual-energy and spectral CT. A new detector technology, the photon-counting detector, is described in detail, and its impact on CT system and clinical applications is analyzed. Many exciting developments in clinical applications, such as cardiac functional imaging and stroke management, are also covered in detail.

Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.

Covering the entire spectrum of this fast-changing field, Diagnostic Imaging: Breast, third edition, is an invaluable resource not only for radiologists, but for all health care professionals involved in the management of breast disease. From screening and diagnostic mammography and tomosynthesis, ultrasound, and MR to contrast-enhanced mammography and molecular imaging, Drs. Wendie Berg and Jessica Leung, along with their expert author team, provide carefully updated information in a concise, bulleted format. Thousands of high-quality illustrations highlight not only image acquisition and interpretation, but also screening guidelines, breast anatomy, genetic testing, image-guided procedures, determining the extent of disease and much more. This book provides essential, clinically-focused details for everyday breast imaging. Features more than 4,000 annotated, updated images throughout, including imaging findings complemented by histopathologic and clinical correlates of the spectrum of breast disease Provides timely coverage of less common but important topics such as gender reassignment, disease-causing mutations and risk assessment, malignancy in pregnancy, nodal disease in breast cancer care, and male breast disease Discusses new technologies, including abbreviated MR, contrast-enhanced mammography, and automated breast ultrasound Includes updated information on evolving medical, oncologic, surgical, and radiation, and oncoplastic treatment of the breast cancer patient, along with discussion of ongoing trials and future directions Offers expanded and updated information on dense breast reporting, screening recommendations, patients at elevated risk, and imaging paradigms in patients with dense breasts, as well as analysis of various updated breast cancer screening guidelines Uses bulleted, succinct text for fast and easy comprehension of essential information Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices

Modern applications of nuclear chemistry concern various scientific disciplines. This new edition of Volume 2 Nuclear- and Radiochemistry: Modern Applications summarizes recent knowledge on radiation measurement and dosimetry, highsensitive, high-selective, and non-destructive analytical technologies, environmental aspects and nuclear dating, state-of-the-art research on actinides and radioelements, nuclear energy, and molecular diagnosis and patient treatment for nuclear medicine. Individual topics are presented by leading experts. This 2nd edition has updated literature references and includes new material throughout. The reader is also referred to the new edition of Volume 1 Nuclear- and Radiochemistry: Introduction.

Multiple sclerosis (MS) is the most prevalent demyelinating disease of the central nervous system (CNS). It affects over 400,000 people in the USA alone and is a common disease world wide. This book will cover a new and emerging field in the development of strategies to treat MS. Until now, the only therapies available for MS treatment have been those directed against inflammation and the immune attack on the CNS. Other treatments are used for symptomatic relief. Remyelination of the CNS has been purely an experimental procedure to date, with many years of research on experimental remyelination in animal models of MS and other myelin disease. As more becomes known about the underlying pathophysiology of MS, it has become apparent that axon loss is a critical component of this primary demyelinating disease and that remyelination of axons at risk, i.e. demyelinated axons, may be the best neuroprotection available. Thus the idea of repairing myelin to both restore conduction to demyelinated fibers, as well as protecting them against future loss, is being seriously explored as a translational therapy. The purpose of this book will be to bring together the experts in the field to discuss what is required to move forward into the clinical application of tissue repair and neuroprotection. The book will begin with a discussion on myelin and the myelinating cell of the CNS and the current state-of-the- art on the cell and molecular biology of the cell, with particular reference toward myelin repair. The book will conclude with a chapter(s) on the clinical application of new myelin repair and axonal protection therapies and the methods by which these new therapies will be evaluated in clinical trials.

This book explains the principles of biosignal processing and its practical applications using MATLAB. Topics include the emergence of biosignals, electrophysiology, analog and digital biosignal processing, signal discretization, electrodes, time and frequency analysis, analog and digital filters, Fourier-transformation, z-transformation, pattern recognition, statistical data analysis, physiological modelling and applications of EEG, ECG, EMG, PCG and PPG signals. Additional scientifi c contributions on motion analysis by guest authors Prof. Dr. J. Subke and B. Schneider as well as classification of PPG signals by Dr. U. Hackstein.

Nuclear chemistry represents a vital fi eld of basic and applied research. This Volume 1 Nuclear- and Radiochemistry: Introduction describes the relevant parameters of stable and unstable atomic nuclei, the various modes of radioactive transformations, the corresponding types of radiation, and fi nally the mechanisms of nuclear reactions. The 2nd edition has updated the chapters throughout with additional material. The reader is also referred to the new edition of Volume 2 Nuclear- and Radiochemistry: Modern Applications.

This Recent Results in Cancer Research volume contains the majority of the invited expert contributions from the First St. Gallen EORTC Gastrointestinal Cancer Conference, held on 22-24 March 2012 in St. Gallen, Switzerland. Written by some of the world s leading experts in the field, the volume constitutes a comprehensive update on recent developments in the imaging, molecular biology, pathology, and multidisciplinary management of early cancer of the gastrointestinal tract. The latest recommendations regarding diagnosis and treatment are provided, and areas of consensus and controversy, identified. While the principal focus is on esophageal and gastric cancer, advances in the treatment of colorectal and pancreatic cancer are also discussed in some detail. This book will be of interest to every clinician involved in the care of patients with gastrointestinal malignancies. "

This comprehensive, case-based resource provides the state-of-the-art knowledge that can help readers improve access and optimize delivery of stroke thrombectomy. Improving access to stroke is of particular importance because patients often misinterpret their symptoms or cannot speak for themselves if they have aphasia. More importantly, access needs to be organized because stroke therapies are all extremely time-sensitive. Scalable, choreographed protocols are necessary for emergency medical systems to 'capture' stroke patients and automatically transport and triage to time-sensitive treatments. Many of the chapters in the first section on Fundamentals and Systems provide valuable insight in improving access to stroke care. Replete with illustrative case studies and emphasizing that treatment approaches to stroke should not be comprised of a one-size-fits-all approach, this illuminating title provides the complete thought, detail, insight and organization that will help readers meet the needs of stroke patients with large vessel occlusions. 12 Strokes: A Case-based Guide to Acute Ischemic Stroke Management examines the primary technical principles that underlie the current thrombectomy approaches. Instead of continuing the conceptual dichotomy of stent vs. aspiration, many of the chapters look at underlying principles and then discuss ways in which the currently available devices and approaches can best exploit them. The variety, creativity and detail in many of these chapters will help the reader develop a deeper understanding that might assist their ability to successfully take care of their next patient that 'doesn't follow the textbook.' In addition, the anatomic and pathophysiologic classification of the core Twelve Chapters will help readers organize their thinking and approach. This knowledge, particularly because it is organized based on common, challenging syndromes, will arm the reader to quickly recognize patterns and deftly adapt their management approaches to the needs of the patient. An invaluable contribution to the clinical literature, 12 Strokes: A Case-based Guide to Acute Ischemic Stroke Management will be of great interest to not only neurosurgeons and neurologists but other specialists, primary care providers, and trainees as well.

Intravascular Ultrasound (IVUS) is now recognized as an important adjunct to conventional angiography and is increasingly used to image atherosclerotic disease process in clinical research. The growing use of this technology has created a need for a resource that combines technical details with illustrative material. An Atlas and Manual of Coronary Intravascular Ultrasound Imaging provides, in a single volume, a practical reference manual that describes the application of the technique, and a superbly illustrated atlas that graphically demonstrates the capabilities of this rapidly evolving technology. Section One, the Manual, describes the rationale, technique, and interpretation of IVUS imaging for standard and evolving applications. It covers normal arterial anatomy, plaque morphology and imaging artifacts, together with measurement techniques and volumetric analysis, and the use of IVUS as a guide for interventional procedures such as atheroplasty, atherectomy, and stenting. In addition, emerging topics including plaque vulnerability and serial surveillance of plaque progression and regression are extensively described. Section Two, the Atlas, reviews these topics with reference to a series of carefully selected clinical cases, which allows the reader to further improve the capability to correctly interpret images obtained using this technique. Developed with the resources of one of the world's leading centers for IVUS imaging, the book systematically introduces coronary imaging with IVUS. A comprehensive reference, An Atlas and Manual of Coronary Intravascular Ultrasound Imaging presents an accessible introduction for the beginner and an invaluable reference for the more experienced practitioner.

Overuse injuries of the musculoskeletal system are common occurrences. Yet most existing volumes on cumulative trauma disorders deal with the subject from an ergonomic and occupational therapy standpoint, and do not provide the all-encompassing synopsis that physicians demand.

Overuse Injuries of the Musculoskeletal System, Second Edition answers the need by presenting a complete overview of the methods for diagnosing and treating the overuse injuries that affect the musculoskeletal system as a whole. Each chapter includes the definition, origins, clinical picture and diagnostics, and treatment for the given injury. The book goes beyond diagnosis and treatment by identifying etiological factors and discussing ways to prevent overuse injuries.

This new edition retains the successful systematic format that made the first edition a bestseller and an invaluable tool for orthopaedists, physical therapists, rheumatologists, radiologists and sports medicine practitioners. This version includes a new chapter on radiologic diagnosis, new chapter on overuse injuries in female athletes and supplements previously-existing chapters with new material.

Now in its fourth edition, this book presents a complete course in electrocardiography (ECG) for students and a reference for advanced trainees and technicians. The author's step-by-step approach lets readers focus only on needed information and proceed at their own pace. Brief and to the point, the text explains how an electrocardiograph works, how to draw a hexaxial system, plot vectors, produce a good ECG tracing, and how to draw a spatial vector. Advanced material is clearly marked, allowing students to work through the complete text with just enough theory to understand the facts and providing advanced trainees with a review and foundation for further study.

This book provides an introduction to next generation smart screening technology for medical image analysis that combines artificial intelligence (AI) techniques with digital screening to develop innovative methods for detecting breast cancer. The authors begin with a discussion of breast cancer, its characteristics and symptoms, and the importance of early screening.They then provide insight on the role of artificial intelligence in global healthcare, screening methods for breast cancer using mammogram, ultrasound, and thermogram images, and the potential benefits of using AI-based systems for clinical screening to more accurately detect, diagnose, and treat breast cancer. Discusses various existing screening methods for breast cancer Presents deep information on artificial intelligence-based screening methods Discusses cancer treatment based on geographical differences and cultural characteristics

This book will help readers to understand the concepts of computational intelligence in automation industries, industrial IoT (IIOT), cognitive systems, data science, and Ecommerce real time applications. The book: Covers computational intelligence in automation industries, industrial IoT (IIOT) , cognitive systems and medical Imaging Discusses intelligent robotics applications with the integration of automation and artificial intelligence Covers foundations of the mathematical concepts applied in robotics and industry automation applications Provides application of artificial intelligence (AI) in the area of computational intelligence The text covers important topics including computational intelligence mathematical modeling, cognitive manufacturing in industry 4.0, artificial intelligence algorithms in robot development, collaborative robots and industrial IoT (IIoT), medical imaging, and multi-robot systems. The text will be useful for graduate students, professional and academic researchers in the fields of electrical engineering, electronics and communication engineering, and computer science. Discussing the advantages of the integrated platform of industry automation, robotics and computational intelligence, this text will be useful for graduate students, professional and academic researchers in the fields of electrical engineering, electronics and communication engineering, and computer science. It enlightens the foundations of the mathematical concepts applied in robotics and industry automation applications.

This book explains transparency in biology with emphasis on bending and absorption, which together are the essence of transparency. The reader is provided with an understanding of why the interior of the body can be made to appear transparent through the application of elementary physics. Based on the principle of transparency, emerging imaging techniques using near-infrared light to view the body transparently are explained with examples such as cancer detection and temperature imaging of deep tissues. This book is useful to many researchers, including biologists, physicists, chemists, materials scientists, and device engineers as well as developers-all who seek a deep understanding of transparency in bioimaging.

This book provides practical and pragmatic guidance in breast MRI for all professionals involved in breast imaging or the care of patients with breast diseases.

eBook available with sample pages: 0203215435

This book explores the physics, technology and applications of particle accelerators. It illustrates the interconnections between applications and basic physical principles, enabling readers to better understand current and upcoming technologies and see beyond the paradigmatic borders of the individual fields. The reader will discover why accelerators are no longer just toys for scientists, but have also become modern and efficient nuclear workhorses. The book starts with an introduction to the relevant technologies and radiation safety aspects of accelerating electrons and ions from several keV to roughly 250 MeV. It subsequently describes the physics behind the interactions of these particle beams with matter. Mathematical descriptions and state-of-the-art computer models of energy-loss and nuclear interactions between the particle beams and targets round out the physics coverage. On this basis, the book then presents the most important accelerator applications in science, medicine, and industry, explaining and comparing more than 20 major application fields, encompassing semiconductors, cancer treatment, and space exploration. Despite the disparate fields involved, this book demonstrates how the same essential technology and physics connects all of these applications.