Authored by a leading educator, this book teaches the fundamental mathematics and physics concepts associated with medical imaging systems. Going beyond mere description of imaging modalities, this book delves into the mechanisms of image formation and image quality common to all imaging systems: contrast mechanisms, noise, and spatial and temporal resolution, making it an important reference for medical physicists and biomedical engineering students. This is an extensively revised new edition of The Physics of Medical X-Ray Imaging by Bruce Hasegawa (Medical Physics Publishing, 1991), and includes a wide range of modalities such as X-ray CT, MRI and SPECT.

This issue of PET Clinics focuses on PET/MRI: Clinical Applications, and is edited by Drs. Drew Torigian and Andreas Kjaer. Articles will include: PET/MRI in Prostate Cancer; PET/MRI in Vascular Disease; PET/MRI in Lymphoma; PET/MRI in Head and Neck Cancer; PET/MRI in Brain Disease; PET/MR in Cancers of GI Tract; PET/MRI in Gynecologic Cancer; Clinical PET/MRI Systems and Patient Workflow; PET/MRI in Heart Disease; PET/MR in Breast Cancer and Lung Cancer; PET/MRI in Musculoskeletal Disorders; PET/MRI in Pediatric Oncology; Clinical PET/MRI: Future Perspectives; and more!

This issue of Physical Medicine and Rehabilitation Clinics of North America will cover musculoskeletal ultrasound in the outpatient. The articles will include: Fundamental Considerations for Ultrasound-Guided Musculoskeletal Interventions, Ultrasound-Guided Shoulder Procedures, Ultrasound-Guided Elbow Procedures, Ultrasound-Guided Hand and Wrist Procedures, Ultrasound-Guided Hip Procedures Ultrasound-Guided Knee Procedures, Ultrasound-Guided Foot and Ankle Procedures, Ultrasound-Guided Spine and Pelvis Procedures and many more exciting topics!

The advent of non-invasive imaging technology, such as magnetic resonance imaging (MRI), has allowed biologists and clinicians to make great strides in unraveling the secrets of the brain. In Magnetic Resonance Neuroimaging: Methods and Protocols, expert researchers in the field provide a comprehensive collection of experimental MRI protocols that can be used to non-invasively interrogate the healthy and diseased brain. The chapters are divided into general techniques, such as the measurement of relaxivity, magnetic resonance spectroscopy, diffusion tensor imaging, and MR reporter genes, as well as specific applications in brain imaging, for example, phenotyping transgenic animals, detecting amyloid plaques, and fMRI in psychiatry. As a volume in the highly successful Methods in Molecular Biology(TM) series, this work contains the type of detailed description and implementation advice that is crucial for getting optimal results. Thorough and cutting-edge, Magnetic Resonance Neuroimaging: Methods and Protocols serves neuroscientists, clinical neurologists, psychiatrists, and radiologists with an excellent compendium of methods easily applied to both animal and human studies and certain to be an excellent resource for translational research.

This issue of the Neurologic Clinics is being edited by the series Consulting Editor, Dr. Randolph Evans, and will be a special issue focusing on patient case studies of a board range of neurological diseases and disorders. Topics and cases covered include, but are not limited to: cerebrovascular disease, multiple sclerosis, syncope, epilepsy, tremor, dementia, neurologic issues in pregnancy, and medicolegal cases.

This book encompasses the full breadth of the super-resolution imaging field, representing modern techniques that exceed the traditional diffraction limit, thereby opening up new applications in biomedicine. It shows readers how to use the new tools to increase resolution in sub-nanometer-scale images of living cells and tissue, which leads to new information about molecules, pathways and dynamics. The book highlights the advantages and disadvantages of the techniques, and gives state-of-the-art examples of applications using microscopes currently available on the market. It covers key techniques such as stimulated emission depletion (STED), structured illumination microscopy (SSIM), photoactivated localization microscopy (PALM), and stochastic optical reconstruction microscopy (STORM). It will be a useful reference for biomedical researchers who want to work with super-resolution imaging, learn the proper technique for their application, and simultaneously obtain a solid footing in other techniques.

This contributed volume focuses on cardiovascular diseases (CVDs), and explores the ways in which signaling mechanisms at the biochemical, molecular, and cellular levels in the blood vessels (vascular) and heart contribute to the underlying causes of development and progression of the CVDs. This volume covers unique topics such as oxidant signaling in vascular and heart diseases and health, cytoskeletal signaling in vascular health and disease, phospholipase signaling in CVDs, lipid signaling in vascular and myocardial health and diseases, and drug discovery in cellular signaling for cardiovascular diseases. This book assembles the most important discoveries made by leaders on the cellular signaling mechanisms operating behind the development and progression of life-threatening CVDs. It is an extremely useful resource for the investigators in the field of CVDs, and opens the discussion for further discovery of efficient management and effective treatment of the CVDs.

The Migraine Brain, edited by David Borsook, Arne May, Peter J. Goadsby, and Richard Hargreaves, makes a major contribution to the field, addressing the increasingly sophisticated neuroimaging techniques that have allowed researchers to begin to define functional and anatomical characteristics of migraine and other less-common types of headache. Of particular focus is how imaging is changing the way we understand migraine. This includes changes in function, structure and chemistry of the migraine brain. Included are sections that focus on particular aspects of migraine, for example the migraine aura: those symptoms that cause visual sensitivity (blinding white light), sensory difficulty (loud noises, painful touch, and hot/cold spells), slurred language, and motor dysfunction.
Extensively illustrated throughout, The Migraine Brain provides a general overview of the history of migraine, its pathophysiology, as well as in-depth details on the Clinical Perspectives and the different imaging techniques in use (MR, fMRI, DTI, VBM, PET, fMRI, and MEG). It also includes details on modulation of the brain using such techniques as TMS. The book concludes with a discussion of future uses of imaging in the diagnosis and treatment of migraines and other headaches.
A collation of the top thinkers in the field and the only book of its kind, The Migraine Brain is necessary reading for neurologists and neuroscientists.

This open access book summarizes the latest scientific findings regarding the biological effects of the Fukushima Daiichi Nuclear Power Plant (FNPP) accident in 2011. Various cases of changes in animals and organisms have been reported since the FNPP accident. However, it is often unknown whether they are actually due to radiation, since the dose or dose-rate are not necessarily associated with the changes observed. This book brings together the works of radiation biologists and ecologists to provide reliable radioecology data and gives insight into future radioprotection. The book examines the environmental pollution and radiation exposure, and contains valuable data from abandoned livestock in the ex-evacuation zone and from wild animals including invertebrates and vertebrates, aqueous and terrestrial animals, and plants that are subjected to long-term exposure in the area still affected by radiation. It also analyzes dose evaluation, and offers new perspectives gained from the accident, as well as an overview for future studies to promote radioprotection of humans and the ecosystem. Since the biological impact of radiation is influenced by various factors, it is difficult to scientifically define the effects of low-dose/low-dose-rate radiation. However, the detailed research data presented can be combined with the latest scientific and technological advances, such as artificial intelligence, to provide new insights in the future. This book is a unique and valuable resource for researchers, professionals and anyone interested in the impact of exposure to radiation or contamination with radioactive materials.

This issue of Neuroimaging Clinics of North America focuses on The Pediatric Cerebellum, and is edited by Drs. Huisman and Andrea Poretti. Articles will include: The role of the pediatric cerebellum in motor functions, neurocognition and behavior: a clinical perspective; Normal development of the cerebellum: from the fetus to the adolescent; Cerebellar malformations; Cerebellar disruptions; Metabolic disorders with cerebellar involvement; Neurocutaenous syndromes with cerebellar involvement; Vascular disorders of the cerebellum; Tumors of the cerebellum; Infectious and inflammatory diseases of the cerebellum; Cerebro-cerebellar network, and more!

This invaluable little pocketbook takes the reader through the basics of chest X-ray examination and interpretation. It covers the range of conditions clinicians are likely to encounter on the wards, and guides the reader through the diagnostic process based on the appearance of the abnormality shown. Suitable for medical students, junior doctors and other health professionals who interpret chest X-rays, including radiographers, nurses and physiotherapists, this text is the ideal solution to increasing your skills and boosting your confidence in using chest X-rays for diagnosis and management. Chest X-Ray Made Easy has garnered international praise as the ideal quick and simple guide to understanding chest X-rays. Concise and succinct - makes interpretation of chest X-rays as simple as possible Comprehensive but easy to understand Specifically designed for junior doctors and students New chapter on what and when to request, and how to do that New images throughout, including obvious and subtle examples of abnormalities Includes CT images and how they correlate with chest X-rays Sections on radiation doses and indications for chest X-rays Sections on chest X-ray appearances in COVID-19 Updated section on imaging in pregnancy Features interpretation of placement of lines, tubes, and of complications Quiz section to test knowledge Established title that is trusted internationally

Medical students preparing for a career in clinical practice must become familiar with a wide range of diagnostic imaging techniques and image-guided interventions. They must learn to identify the indications for radiological examination and recognize the role each procedure plays in the workup, diagnosis, and therapeutic management of patients. That is why Squire's Fundamentals of Radiology has been such an important, long-standing resource for medical students, physicians, and other professionals at all stages of their careers. It teaches essential topics in the radiology curriculum and features hundreds of illustrative cases clinicians can turn to again and again in practice. In this long-awaited seventh edition, Robert Novelline provides more than 600 new high-resolution images representing the current breadth of radiological procedures: conventional x-rays, ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), angiography, radioisotope scanning, positron emission tomography (PET), and molecular imaging. This edition's expanded coverage addresses dual energy CT, breast tomosynthesis, PET-MR scanning, and tractography brain imaging, along with best practices for managing patient experiences during and after examination. All new images were produced at a major teaching hospital using state-of-the-art imaging technologies. Squire's Fundamentals of Radiology is designed to be read cover to cover by students, with concepts, principles, and methods progressing in a logical, cumulative manner. It also serves as an invaluable tool for teachers and an indispensable reference for seasoned practitioners. Written by a radiologist who has trained thousands of medical students and residents, this textbook is the clear choice for excelling in the general practice of radiology.

Remarkable progress in neuro-oncology due to increased utilization of advanced imaging in clinical practice continues to accelerate in recent years. Refinements in magnetic resonance imaging (MRI) and computed tomography (CT) technology, and the addition of newer anatomical, functional, and metabolic imaging methods, such as MRS, fMRI, diffusion MRI, and DTI MRI have allowed brain tumor patients to be diagnosed much earlier and to be followed more carefully during treatment. With treatment approaches and the field of neuro-oncology neuroimaging changing rapidly, this second edition of the Handbook of Neuro-Oncology Neuroimaging is so relevant to those in the field, providing a single-source, comprehensive, reference handbook of the most up-to-date clinical and technical information regarding the application of neuro-Imaging techniques to brain tumor and neuro-oncology patients. This new volume will have updates on all of the material from the first edition, and in addition will feature several new important chapters covering diverse topics such as advanced imaging techniques in radiation therapy, therapeutic treatment fields, response assessment in clinical trials, surgical planning of neoplastic disease of the spine, and more. It will also serve as a resource of background information to neuroimaging researchers and basic scientists with an interest in brain tumors and neuro-oncology.

Technical Fundamentals of Radiology and CT is intended to cover all issues related to radiology and computed tomography, from the technological point of view, both for understanding the operation of all devices involved and for their maintenance. It is intended for students and a wide range of professionals working in various fields of radiology, those who take images and know little about the workings of the devices, and professionals who install, maintain and solve technological problems of all radiological systems used in health institutions.

The 11 chapters in this book have been selected from the contents of the Interventional Radiology section in Grainger & Allison's Diagnostic Radiology 6e. These chapters provide a succinct up-to-date overview of current imaging techniques and their clinical applications in daily practice and it is hoped that with this concise format the user will quickly grasp the fundamentals they need to know. Throughout these chapters, the relative merits of different procedures and techniques are described, variations are discussed and recent imaging advances are detailed.

This issue of PET Clinics focuses on PET/MRI: Advances in Instrumentation and Quantitative Procedures. Articles will include: Advances in clinical PET/MRI instrumentation; Magnetic resonance imaging-guided attenuation correction of positron emission tomography data in PET/MRI; Magnetic resonance imaging-guided partial volume correction of positron emission tomography data in PET/MRI; Magnetic resonance imaging-guided derivation of the input function for PET kinetic modeling; Innovations in small-animal PET/MRI instrumentation; Dual-modal PET/MRI molecular imaging probes; Magnetic resonance imaging-guided motion compensation of positron emission tomography data in PET/MRI; Attenuation correction for MR coils in combined PET/MR imaging; and more!

This book describes the technical problems and solutions for automatically recognizing and parsing a medical image into multiple objects, structures, or anatomies. It gives all the key methods, including state-of- the-art approaches based on machine learning, for recognizing or detecting, parsing or segmenting, a cohort of anatomical structures from a medical image. Written by top experts in Medical Imaging, this book is ideal for university researchers and industry practitioners in medical imaging who want a complete reference on key methods, algorithms and applications in medical image recognition, segmentation and parsing of multiple objects. Learn: Research challenges and problems in medical image recognition, segmentation and parsing of multiple objects Methods and theories for medical image recognition, segmentation and parsing of multiple objects Efficient and effective machine learning solutions based on big datasets Selected applications of medical image parsing using proven algorithms

This issue of Radiologic Clinics of North America focuses on Topics in Transplantation Imaging. Articles will include: Surgical and imaging workup of the liver pre-transplantation donor and recipient; Surgical techniques and imaging complications of liver transplantation; Surgical and imaging workup of the renal pre-transplantation donor and recipient; Imaging complications of renal transplantation; Surgical and imaging workup of the pancreas pre-transplantation donor and recipient; Interventional and surgical techniques in solid organ transplantation; Complications of immunosuppresive therapy in solid organ transplantation; Pediatric thoracic organ transplantation: current indications, techniques, and imaging findings; Pediatric abdominal organ transplantation: update on current practical imaging assessment; Surgical issues of lung transplantation; Imaging complications of lung transplantation; Current indications, techniques, and imaging findings of stem cell treatment and bone marrow transplant; and more!

"Handbook of Capsule Endoscopy "is a concise guide to the clinical diagnostic use of capsule endoscopy, a non-invasive imaging technology of the gastrointestinal tract. This book is written by an international team with over 30 authors from 8 countries, mainly China, Britain, Israel, Italy, Germany, Korea, United Arab Emirates and the United States.

This book introduces nearly all aspects of capsule endoscopy, including the six devices currently in use, the set up procedures, indications and contraindications, its application in three organs, special use in pediatrics, safety issues and case presentations. This book is an ideal reference work for physicians and surgeons who wish to utilize this helpful imaging technology.

Prof. Zhaoshen Li and Associate Prof. Zhuan Liao are doctors in Changhai Hospital, the Second Military Medical University, Shanghai, China. Mark McAlindon is a consultant gastroenterologist and the directorate of gastroenterology in Royal Hallamshire Hospital, England, the United Kingdom.

This state-of-the-art set of handbooks provides medical physicists with a comprehensive overview of the field of nuclear medicine. In addition to describing the underlying, fundamental theories of the field, it includes the latest research and explores the practical procedures, equipment, and regulations that are shaping the field and it's future. This set is split into three volumes, respectively titled: Instrumentation and Imaging Procedures; Modelling, Dosimetry and Radiation Protection; and Radiopharmaceuticals and Clinical Applications. Volume one, Instrumentation and Imaging Procedures, focuses primarily on providing a comprehensive review into the detection of radiation, beginning with an introduction to the history of nuclear medicine to the latest imaging technology. Volume two, Modelling, Dosimetry and Radiation Protection, explores the applications of mathematical modelling, dosimetry, and radiation protection in nuclear medicine. The third and final volume, Radiopharmaceuticals and Clinical Applications, highlights the production and application of radiopharmaceuticals and their role in clinical nuclear medicine practice. These books will be an invaluable resource for libraries, institutions, and clinical and academic medical physicists searching for a complete account of what defines nuclear medicine. The most comprehensive reference available providing a state-of-the-art overview of the field of nuclear medicine Edited by a leader in the field, with contributions from a team of experienced medical physicists, chemists, engineers, scientists, and clinical medical personnel Includes the latest practical research in the field, in addition to explaining fundamental theory and the field's history

The 8 chapters in this book have been selected from the contents of the Paediatric Imaging section in Grainger & Allison's Diagnostic Radiology 6e. These organ-specific chapters provide a succinct up-to-date overview of current imaging techniques and their clinical applications in daily practice and it is hoped that with this concise format the user will quickly grasp the fundamentals they need to know. Throughout these chapters, the relative merits of different imaging investigations are described, variations are discussed and recent imaging advances are detailed.

The 17 chapters in this book have been selected from the contents of the Chest and Cardiovascular System section in Grainger & Allison's Diagnostic Radiology 6e. These chapters provide a succinct up-to-date overview of current imaging techniques and their clinical applications in daily practice and it is hoped that with this concise format the user will quickly grasp the fundamentals they need to know. Throughout these chapters, the relative merits of different imaging investigations are described, variations are discussed and recent imaging advances are detailed.

The 9 chapters in this book have been selected from the contents of the Musculoskeletal System section in Grainger & Allison's Diagnostic Radiology 6e. These chapters provide a succinct up-to-date overview of current imaging techniques and their clinical applications in daily practice and it is hoped that with this concise format the user will quickly grasp the fundamentals they need to know. Throughout these chapters, the relative merits of different imaging investigations are described, variations are discussed and recent imaging advances are detailed. Please note that imaging techniques of the spine are considered in the separate section "The Spine" in Grainger & Allison's Diagnostic Radiology 6e.

The 8 chapters in this book have been selected from the contents of the Neuroimaging section in Grainger & Allison's Diagnostic Radiology 6e. These chapters provide a succinct up-to-date overview of current imaging techniques and their clinical applications in daily practice and it is hoped that with this concise format the user will quickly grasp the fundamentals they need to know. Throughout these chapters, the relative merits of different imaging investigations are described, variations are discussed and recent imaging advances are detailed. Please note that imaging techniques of the spine are considered in the separate section "The Spine" in Grainger & Allison's Diagnostic Radiology 6e.