With the increasing interest in the experimental and clinical application of molecular imaging many institutions create research groups or interdisciplinary centers focussing on the complex development process of this new methodology. The aim for this textbook of molecular imaging is to provide an up to date review of this rapidly growing field and to discuss basic methodological aspects necessary for the interpretation of experimental and clinical results. Emphasis is placed on the interplay of imaging technology and probe development, since the physical properties of the imaging approach need to be closely linked with the biologic application of the probe (i.e. nanoparticles and microbubbles). Various chemical strategies are discussed and related to the biologic applications. Reporter-gene imaging is being addressed not only in experimental protocols, but also first clinical applications are discussed. Finally, strategies of imaging to characterize apoptosis and angiogenesis are described and discussed in the context of possible clinical translation.

Preoperative imaging is increasingly being adopted for preoperative planning in plastic and reconstructive surgery. Accurate preoperative analysis can reduce the length of operations and maximize surgical design and dissection techniques. Imaging for Plastic Surgery covers the techniques, applications, and potentialities of medical imaging technology in plastic and reconstructive surgery. Presenting state-of-the-art research on evolving imaging modalities, this cutting-edge text: Provides a practical introduction to imaging modalities that can be used during preoperative planning Addresses imaging principles of the face, head, neck, breast, trunk, and extremities Identifies the strengths and weaknesses of all available imaging modalities Demonstrates the added value of imaging in different clinical scenarios Comprised of contributions from world-class experts in the field, Imaging for Plastic Surgery is an essential imaging resource for surgeons, radiologists, and patient care professionals.

Key Features: • Features case-based scenarios in Critical Care as well as has a section on Tropical Diseases. • Appeals to a wide audience of trainees and consultants of Critical Care Medicine, Internal Medicine, Anaesthesiology, Pulmonary Medicine and those working in the ICU, due to its clinical relevance. • Reduces the dependency on the radiologist and help the physicians to save time which would enhance the quality of patient care.

Radiology to me is an art more than a science; an art of imaging the human body, and an art of extracting information from an image. Radiology today is a vital specialty that almost no other medical specialty can work without. Congenital anomalies and syndromes are complex subjects in all medical specialties. They require knowledge of the normal anatomy and of the embryological basis of organogenesis. The importance of recognizing a congenital malformation or an anomaly, which can be the tip of an iceberg of a more complex syndrome, is to prevent future manifestations of a s- drome if possible or to reduce its severity. Due to this concept, I had an interest in studying how to use the radiological modalities in diagnosing congenital malfor- tions as early as possible. Although radiology offers very powerful tools for diag- sis, the basics of medicine are still the main tools to be used for diagnosis. History, observation, clinical examination, and laboratory investigations are essential elements for diagnosis, which need to be used before radiology investigations are initiated. The idea of this book is based on a simple principle: it is to link radiology to these basic medical tools. The book is written for junior radiologists, radiology students, and doctors interested in congenital malformations and syndromes in any specialty. Each disease is represented with a de? nition, description, etiology, diagnostic cri- ria, main symptoms, and its typical diagnostic radiological features on the modern radiological modalities available today.

Dermoscopy is a noninvasive skin imaging technique that uses optical magnification and either liquid immersion or cross-polarized lighting to make subsurface structures more easily visible when compared to conventional clinical images. It allows for the identification of dozens of morphological features that are particularly important in identifying malignant melanoma. Dermoscopy Image Analysis summarizes the state of the art of the computerized analysis of dermoscopy images. The book begins by discussing the influence of color normalization on classification accuracy and then: Investigates gray-world, max-RGB, and shades-of-gray color constancy algorithms, showing significant gains in sensitivity and specificity on a heterogeneous set of images Proposes a new color space that highlights the distribution of underlying melanin and hemoglobin color pigments, leading to more accurate classification and border detection results Determines that the latest border detection algorithms can achieve a level of agreement that is only slightly lower than the level of agreement among experienced dermatologists Provides a comprehensive review of various methods for border detection, pigment network extraction, global pattern extraction, streak detection, and perceptually significant color detection Details a computer-aided diagnosis (CAD) system for melanomas that features an inexpensive acquisition tool, clinically meaningful features, and interpretable classification feedback Presents a highly scalable CAD system implemented in the MapReduce framework, a novel CAD system for melanomas, and an overview of dermatological image databases Describes projects that made use of a publicly available database of dermoscopy images, which contains 200 high-quality images along with their medical annotations Dermoscopy Image Analysis not only showcases recent advances but also explores future directions for this exciting subfield of medical image analysis, covering dermoscopy image analysis from preprocessing to classification.

The new edition of this established text has been thoroughly revised and updated. It is divided into six parts. The first two parts cover the X--ray tube and X--ray generators. Part three looks at general, multipurpose radiographic equipment. Part four considers fluroscopic equipment, and the remaining two parts provide accounts of more specialized radiographic equipment and computer--based imaging modalities.

Over the past decade, the field of image processing has made tremendous advances. One type of image processing that is currently of particular interest is "tomographic imaging," a technique for computing the density function of a body, or discontinuity surfaces of this function. Today, tomography is widely used, and has applications in such fields as medicine, engineering, physics, geophysics, and security. The Radon Transform and Local Tomography clearly explains the theoretical, computational, and practical aspects of applied tomography. It includes sufficient background information to make it essentially self-contained for most readers.

This new edition is a complete guide to diagnostic imaging of the chest and cardiovascular system. Beginning with an overview of chest radiology, techniques and anatomy, the following sections discuss imaging for different pulmonary diseases. The second part of the book covers diagnostic imaging for cardiovascular disorders and includes a chapter on children with congenital heart disease. The fourth edition has been fully revised to provide radiologists with the latest information in their field, and includes new chapters on basic patterns of lung disease on CT, and miscellaneous interstitial lung diseases such as acute respiratory distress syndrome, lipoid pneumonia, and emphysema. The comprehensive text features discussion on the increasing use of image-guided interventions, and is further enhanced by radiological images and tables. Key points Fourth edition presenting latest advances in diagnostic imaging for pulmonary and cardiovascular disorders Fully revised text with new topics added Highly illustrated with radiological images and tables Previous edition (9788184488685) published in 2010

The Manual of Venous and Lymphatic Diseases constitutes a concise but comprehensive and contemporary description of the nature and management of venous and lymphatic diseases. This innovative book instructs the post-graduate trainee in phlebology and is also valuable to undergraduate students wishing to gain a broader knowledge than is available in general surgical texts. Addtionally, it is a useful reference for practising phelebologists, vascular surgeons and imaging specialists. The text covers basic principles, diagnosis and treatment of chronic venous disease, venous thrombo-embolism, lymphoedema and vascular malformations.

Develop a solid understanding of ultrasound of the abdomen and pelvis with this practical, point-of-care reference in the popular Diagnostic Ultrasound series. Written by leading experts in the field, the second edition of Diagnostic Ultrasound: Abdomen and Pelvis offers detailed, clinically oriented coverage of ultrasound imaging of this complex area and includes illustrated and written correlation between ultrasound findings and other modalities. The most comprehensive reference in its field, this image-rich resource helps you achieve an accurate ultrasound diagnosis for every patient. Features nearly 15 new chapters that detail updated diagnoses, new terminology, new methodology, new criteria and guidelines, a new generation of scanners, and more Includes 2,500 high-quality images including grayscale, color, power, and spectral (pulsed) Doppler imaging in each chapter and, when applicable, contrast-enhanced ultrasound; plus new videos and animations online Discusses new polycystic ovary syndrome (PCOS) criteria, updated pancreatic cyst guidelines, new ovarian cysts recommendations, shear wave elastography for liver fibrosis, and more Correlates ultrasound findings with CT and MR for improved understanding of disease processes and how ultrasound complements other modalities for a given disease Covers cutting-edge ultrasound techniques, including microbubble contrast and contrast-enhanced US (CEUS) for liver imaging Contains time-saving reference features such as succinct and bulleted text, a variety of test data tables, key facts in each chapter, annotated images, and an extensive index Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

This book illustrates the significance of biomedical engineering in modern healthcare systems. Biomedical engineering plays an important role in a range of areas, from diagnosis and analysis to treatment and recovery and has entered the public consciousness through the proliferation of implantable medical devices, such as pacemakers and artificial hips, as well as the more futuristic technologies such as stem cell engineering and 3-D printing of biological organs. Starting with an introduction to biomedical engineering, the book then discusses various tools and techniques for medical diagnostics and treatment and recent advances. It also provides comprehensive and integrated information on rehabilitation engineering, including the design of artificial body parts, and the underlying principles, and standards. It also presents a conceptual framework to clarify the relationship between ethical policies in medical practice and philosophical moral reasoning. Lastly, the book highlights a number of challenges associated with modern healthcare technologies.

With the development of rapidly increasing medical imaging modalities and their applications, the need for computers and computing in image generation, processing, visualization, archival, transmission, modeling, and analysis has grown substantially. Computers are being integrated into almost every medical imaging system. Medical Image Analysis and Informatics demonstrates how quantitative analysis becomes possible by the application of computational procedures to medical images. Furthermore, it shows how quantitative and objective analysis facilitated by medical image informatics, CBIR, and CAD could lead to improved diagnosis by physicians. Whereas CAD has become a part of the clinical workflow in the detection of breast cancer with mammograms, it is not yet established in other applications. CBIR is an alternative and complementary approach for image retrieval based on measures derived from images, which could also facilitate CAD. This book shows how digital image processing techniques can assist in quantitative analysis of medical images, how pattern recognition and classification techniques can facilitate CAD, and how CAD systems can assist in achieving efficient diagnosis, in designing optimal treatment protocols, in analyzing the effects of or response to treatment, and in clinical management of various conditions. The book affirms that medical imaging, medical image analysis, medical image informatics, CBIR, and CAD are proven as well as essential techniques for health care.

Ophthalmic Imaging serves as a reference for the practicing ophthalmic imager. Ophthalmic imaging combines photography and diagnostic imaging to provide insight into not only the health of the eye, but also the health of the human body as a whole. Ophthalmic photographers are specialists in imaging through and in the human eye, one of the only parts of the body where the circulation and nervous system is visible non-invasively. With technical perspective as context, this book will provide instructional techniques as well as the background needed for problem solving in this exciting field. The book covers all aspects of contemporary ophthalmic imaging and provides image support to ophthalmologists and sub-specialties including retinal specialists, corneal specialists, neuro-ophthalmologists, and ocular oncologists. This text serves as a reference for the practicing ophthalmic imager, or to imagers just getting started in the field.

Of the research areas devoted to biomedical sciences, the study of the brain remains a field that continually attracts interest due to the vast range of people afflicted with debilitating brain disorders and those interested in ameliorating its effects. To discover the roots of maladies and grasp the dynamics of brain functions, researchers and practitioners often turn to a process known as brain source localization, which assists in determining the source of electromagnetic signals from the brain. Aiming to promote both treatments and understanding of brain ailments, ranging from epilepsy and depression to schizophrenia and Parkinson's disease, the authors of this book provide a comprehensive account of current developments in the use of neuroimaging techniques for brain analysis. Their book addresses a wide array of topics, including EEG forward and inverse problems, the application of classical MNE, LORETA, Bayesian based MSP, and its modified version, M-MSP. Within the ten chapters that comprise this book, clinicians, researchers, and field experts concerned with the state of brain source localization will find a store of information that can assist them in the quest to enhance the quality of life for people living with brain disorders.

This one-of-a-kind resource provides a very readable description of the methods used for image reconstruction in magnetic resonance imaging, X-ray computed tomography, and single photon emission computed tomography. The goal of this fascinating work is to provide radiologists with a practical introduction to mathematical methods so that they may better understand the potentials and limitations of the images used to make diagnoses. Presented in four parts, this state-of-the-art text covers (1) an introduction to the models used in reconstruction, (2) an explanation of the Fourier transform, (3) a brief description of filtering, and (4) the application of these methods to reconstruction. In order to provide a better understanding of the reconstruction process, this comprehensive volume draws analogies between several different reconstruction methods. This informative reference is an absolute must for all radiology residents, as well as graduate students and professionals in the fields of physics, nuclear medicine, and computer-assisted tomography.

Covering the entire spectrum of this fast-changing field, Diagnostic Imaging: Oncology, second edition, is an invaluable resource for radiologists and surgical and medical oncologists-anyone who requires an easily accessible, highly visual reference covering cancer imaging and staging. A team of renowned experts in radiology, oncology, and body imaging provide carefully updated information and an abundance of high-quality images throughout, making this edition a useful learning tool as well as a handy reference for daily practice. Features nearly 3,000 annotated images, including lavish, full-color graphics for each cancer stage and many new illustrations throughout Brings you up to speed with updated TNM and grading tables from the new American Joint Committee on Cancer (AJCC) Cancer Staging Manual and updated WHO classifications Includes new chapters covering radiological staging of tumors recently introduced in the AJCC 8th edition and new chapter divisions that reflect the current AJCC staging system Provides practical, easy-to-find details on routes of spread, imaging techniques, suggestions for treatment based on tumor stages identified in a patient's imaging studies, and extensive imaging examples of a variety of cancers in many different stages Begins each chapter with updated TNM staging tables from the AJCC followed by full-color graphic depictions of TNM criteria Uses bulleted, succinct text for quick comprehension of essential information, as well as a consistent chapter format offering an Overview, Relevant Pathology, Imaging Findings, Clinical Issues, Reporting Checklist, and Selected References Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices

This impressive dictionary/handbook presents the nomenclature characteristic of nuclear medicine, explaining the meaning and current usage of a large variety of terms. It is designed as a ready-to-use and simple guide, arranged in alphabetical order with additional basic information assembled in the appendices. The single volume offers a look into the multidisciplinary world of this specialty. The field of nuclear medicine has emerged as an integrated medical discipline. It is an example of the convergence of many scientific disciplines with those of medicine emphasizing the use of radionuclides in research, diagnosis and therapy. The dictionary/handbook will be of importance to individuals in nuclear medicine and the following fields: physics, instrumentation, techniques, computers, radiopharmacology and radiopharmacy, radioimmunoassay, radiobiology and radiation protection, quality control, math and statistics, nuclear science and technology, radiology, ultrasound, and nuclear magnetic resonance.

In the past two decades, significant advances in magnetic resonance microscopy (MRM) have been made possible by a combination of higher magnetic fields and more robust data acquisition technologies. This technical progress has enabled a shift in MRM applications from basic anatomical investigations to dynamic and functional studies, boosting the use of MRM in biological and life sciences. This book provides a simple introduction to MRM emphasizing practical aspects relevant to high magnetic fields. It focuses on biological applications and presents a number of selected examples of neuroscience applications. The text is mainly intended for those who are beginning research in the field of MRM or are planning to incorporate high-resolution MRI in their neuroscience studies.

This is a vital revision aid for postgraduate radiology students taking the Fellowship of the Royal College of Radiology (FRCR) Part 2 final exams. Part 2 comprises two elements: 2a includes a series of six multiple choice exams covering the major body systems, and 2b contains a written exam and an oral viva typically taken at the beginning of the fourth year of specialty training.

This book is an informed, educational and abundantly illustrated guide to the imaging knowledge that medical students in the clinical years of their undergraduate studies will be required to get to know, understand and recall in order to negotiate successfully their finals exams. Via the popular and instructive case-based format, readers are guided through 100 cases chosen specifically to reflect what the authors consider is necessary knowledge for finals, and imaging modalities that students can reasonably expect to encounter with a resulting emphasis on plain film with some CT and MR.

An in-depth knowledge of the wide spectrum of normal gallbladder appearances is vital to appropriate clinical workup and the correct diagnosis of patients with upper abdominal symptoms. This book covers the range of appearances of the normal gallbladder and its variants, including discussions of anatomy, embryology, and imaging techniques to promote a better understanding of the subject. Anomalies of number, location, and form are each addressed in separate chapters, and discussions of imaging artifacts of the gallbladder and pseudolesions, which can mimic gallbladder disease, are also included. A short chapter on the appearance of the fetal gallbladder is included to round out this comprehensive volume.

This handbook provides clinical guidance to the practicing physician on the diagnosis and treatment of Interstitial Lung Diseases (ILD). A contributed work with invited chapters which draw on the knowledge and experience of recognised global leaders in respiratory medicine, it is authoritative, concise and portable and is intended for use in a fast-paced clinical setting. The book: offers practical tips and clear guidance for clinicians provides detailed explanations of the main therapeutic options for each individual ILD contains high-quality visuals, including radiology and histopathology of the most common as well as some of the rarer ILDs discusses individual ILDs and has topics common to all including critical care, lung transplantation and palliative care navigates clinicians through cases with decision making guidelines and algorithms includes appendices with international practice guidelines, sample patient information sheets and other helpful resources. Emphasizing how to perform a thorough assessment of an ILD patient for accurate diagnosis and their subsequent effective management, this is both a gold standard text as well as a daily companion for physicians caring for ILD patients. A first-of-its-kind, it will become the go-to guide for all clinicians who manage patients with ILD.

Ophthalmic Imaging serves as a reference for the practicing ophthalmic imager. Ophthalmic imaging combines photography and diagnostic imaging to provide insight into not only the health of the eye, but also the health of the human body as a whole. Ophthalmic photographers are specialists in imaging through and in the human eye, one of the only parts of the body where the circulation and nervous system is visible non-invasively. With technical perspective as context, this book will provide instructional techniques as well as the background needed for problem solving in this exciting field. The book covers all aspects of contemporary ophthalmic imaging and provides image support to ophthalmologists and sub-specialties including retinal specialists, corneal specialists, neuro-ophthalmologists, and ocular oncologists. This text serves as a reference for the practicing ophthalmic imager, or to imagers just getting started in the field.

Radiation dosimetry has made great progress in the last decade, mainly because radiation therapy is much more widely used. Since the first edition, many new developments have been made in the basic methods for dosimetry, i.e. ionization chambers, TLD, chemical dosimeters, and photographic films. Radiation Dosimetry: Instrumentation and Methods, Second Edition brings to the reader these latest developments. Written at a high level for medical physicists, engineers, and advanced dosimetrists, it concentrates only on evolvement during the last decade, relying on the first edition to provide the basics.

This innovative textbook is modelled on problem-based learning. It bridges the gap between academic neuroanatomy and clinical neurology and effectively takes the reader from the classroom to the clinic, so that learning can be applied in practice. This second edition has been updated and expanded to include many more clinical cases within both the book and the accompanying Wweb site. This book and the associated Web site will be of practical value to all the professionals who deal with people who have neurological conditions, as well as being invaluable to medical students and residents. This includes physiatrists (rehabilitation medicine specialists), physiotherapists, occupational therapists and speech therapists, and nurses who specialize in the care of neurological patients. We think that this text will also be of value for family physicians and specialists in internal medicine and pediatrics, all of whom must differentiate between organic pathology of the nervous system and other conditions.