Developing an effective computer-aided diagnosis (CAD) system for lung cancer is of great clinical importance and can significantly increase the patient's chance for survival. For this reason, CAD systems for lung cancer have been investigated in a large number of research studies. A typical CAD system for lung cancer diagnosis is composed of four main processing steps: segmentation of the lung fields, detection of nodules inside the lung fields, segmentation of the detected nodules, and diagnosis of the nodules as benign or malignant. This book overviews the current state-of-the-art techniques that have been developed to implement each of these CAD processing steps. Overviews the latest state-of-the-art diagnostic CAD systems for lung cancer imaging and diagnosis Offers detailed coverage of 3D and 4D image segmentation Illustrates unique fully automated detection systems coupled with 4D Computed Tomography (CT) Written by authors who are world-class researchers in the biomedical imaging sciences Includes extensive references at the end of each chapter to enhance further study Ayman El-Baz is a professor, university scholar, and chair of the Bioengineering Department at the University of Louisville, Louisville, Kentucky. He earned his bachelor's and master's degrees in electrical engineering in 1997 and 2001, respectively. He earned his doctoral degree in electrical engineering from the University of Louisville in 2006. In 2009, he was named a Coulter Fellow for his contributions to the field of biomedical translational research. He has 17 years of hands-on experience in the fields of bio-imaging modeling and noninvasive computer-assisted diagnosis systems. He has authored or coauthored more than 500 technical articles (132 journals, 23 books, 57 book chapters, 211 refereed-conference papers, 137 abstracts, and 27 U.S. patents and disclosures). Jasjit S. Suri is an innovator, scientist, a visionary, an industrialist, and an internationally known world leader in biomedical engineering. He has spent over 25 years in the field of biomedical engineering/devices and its management. He received his doctorate from the University of Washington, Seattle, and his business management sciences degree from Weatherhead School of Management, Case Western Reserve University, Cleveland, Ohio. He was awarded the President's Gold Medal in 1980 and named a Fellow of the American Institute of Medical and Biological Engineering for his outstanding contributions in 2004. In 2018, he was awarded the Marquis Life Time Achievement Award for his outstanding contributions and dedication to medical imaging and its management.

This book is a guide for the constantly growing community of the users of medical thermal imaging. It describes where and how an infrared equipment can be used in a strictly standardised way and how one can ultimately comprehensively report the findings. Due to their insight into the complex mechanisms behind the distribution of surface temperature, future users of medical thermal imaging should be able to provide careful, and cautious, interpretations of infrared thermograms, thus avoiding the pitfalls of the past. The authors are well-known pioneers of the technique of infrared imaging in medicine who have combined strict standard-based evaluation of medical thermal images with their expertise in clinical medicine and related fields of health management.

Kinematic MRI refers to imaging a joint through a range of motion to examine the interactions between the soft tissue and osseous anatomy that comprise the joint. Kinematic MRI techniques were developed because various pathologic conditions are dependent on the specific position of the joint or in response to loading or stress. Importantly, static-view MRI examinations often miss abnormal findings because the joint is not assessed through a range of motion. Accordingly, the functional information obtained using kinematic MRI frequently serves to identify the underlying abnormality or to supplement the information acquired with standard MR imaging techniques. Kinematic MRI of the Joints is the first textbook on this important, emerging clinical MRI application. For each joint, it presents pertinent functional anatomy, kinesiology, and clinical information; describes the kinematic MRI protocol and technique; explains the normal kinematics; and provides a thorough presentation of the pathokinematics. Multiple case examples illustrate the usefulness of kinematic MRI of the joints for diagnosis or elucidation of pathologic conditions. Each section of this book is co-authored by an leading musculoskeletal radiologist orthopedic surgeon as well as by an academic-based physical therapist/biomechanist.

Appraising cancer as a major medical market in the 2010s, Wall Street investors placed their bets on single-technology treatment facilities costing $100-$300 million each. Critics inside medicine called the widely-publicized proton-center boom "crazy medicine and unsustainable public policy." There was no valid evidence, they claimed, that proton beams were more effective than less costly alternatives. But developers expected insurance to cover their centers' staggeringly high costs and debts. Was speculation like this new to health care? Cancer, Radiation Therapy, and the Market shows how the radiation therapy specialty in the United States (later called radiation oncology) coevolved with its device industry throughout the twentieth-century. Academic engineers and physicians acquired financing to develop increasingly powerful radiation devices, initiated companies to manufacture the devices competitively, and designed hospital and freestanding procedure units to utilize them. In the process, they incorporated market strategies into medical organization and practice. Although palliative benefits and striking tumor reductions fueled hopes of curing cancer, scientific research all too often found serious patient harm and disappointing beneficial impact on cancer survival. This thoroughly documented and provocative inquiry concludes that public health policy needs to re-evaluate market-driven high-tech medicine and build evidence-based health care systems.

Revising for the final FRCR examination is a challenging task. The candidate has to balance their revision time between image interpretation practice, learning facts and refining presentation skills. Whilst it is better to gain an understanding of the underlying mechanisms that result in a radiological abnormality, it is an unavoidable truth that some things just have to be rote learned. This revision guide demonstrates a proven mechanism for organising thoughts, directing revision towards the more important diagnoses and providing clarity when confronted with the mountain of information expected to retained and recalled during the FRCR viva exam. Mnemonics typically uses word-based cues to enhance memory, reduce cognitive load and aid learning. This guide relies on acronyms and acrostics - proven to be highly effective for rote learning and focused revision. FRCR examination candidates will appreciate the unified structure throughout, with extensive use of sample images followed by sets of differential diagnoses and mnemonic listings. For each stem of the mnemonic, the main radiological findings and useful distinguishing features are listed and a model answer is given. A short discussion of the main diagnoses follows, increasing comprehension and aiding examination confidence.

This book is about pulse nuclear magnetic resonance (NMR), with its techniques, the information to be obtained, and practical advice on performing experiments. The emphasis is on the motivation and physical ideas underlying NMR experiments and the actual techniques, including the hardware used. The level is generally suitable for those to whom pulse NMR is a new technique, be they students in chemistry or physics on the one hand and research workers in biology, geology, or agriculture, on the other. The book can be used for a senior or first year graduate course where it could supplement the standard NMR texts.

Soft tissue tumours are extremely common although difficult to understand due to a large number of sub-types, leading to a significant increase in their imaging in the last decade. This highly illustrated practical book provides a simplified, systematic approach to imaging, reporting and diagnosing these tumours. It covers all the modalities with emphasis on ultrasound and MRI, along with the newer techniques in these modalities. This concise guide to soft tissue lesions, will help clinicians to quickly understand the spectrum of tumours and identify the appropriate imaging techniques to best serve their patients. Key Features: * Provides guidance by international experts on various types of soft tissue tumours (benign, malignant and tumour mimics), their relevant imaging features to help suggest specific or differential diagnosis and when to biopsy and when to refer to specialist centres. * Proves to be an excellent resource for general and specialist radiologists, radiology trainees, sonographers, sarcoma surgeons and oncologists for day-to-day reporting. * Discusses the importance of proper imaging and biopsy of tumors and the implications of unplanned excisions in sarcoma.

This book presents a vast collection of radiologic images of cases seen in a very busy emergency room. It encompasses common and very unusual pathology and every imaging modality. The book is divided into four parts on pathology of the vascular system, chest, abdomen and pelvis and reproductive organs. Images obtained with the modalities that best depict the abnormality in question are presented, with marking of the salient pathology and explanation of the abnormal imaging features in concise captions. Whenever possible, differential diagnosis is covered using further images and guidance is also provided on selection of additional modalities to confirm the diagnosis. The book will help residents to analyze different diseases and relate pathophysiology to imaging and assist students in appreciating what is abnormal. It will be a useful guide for the busy practicing radiologist and aid clinicians in understanding the complexity of these cases and delivering better focused treatment.p>

This scholarly set of well-harmonized volumes provides indispensable and complete coverage of the exciting and evolving subject of medical imaging systems. Leading experts on the international scene tackle the latest cutting-edge techniques and technologies in an in-depth but eminently clear and readable approach. Complementing and intersecting one another, each volume offers a comprehensive treatment of substantive importance to the subject areas. The chapters, in turn, address topics in a self-contained manner with authoritative introductions, useful summaries, and detailed reference lists. Extensively well-illustrated with figures throughout, the five volumes as a whole achieve a unique depth and breath of coverage. As a cohesive whole or independent of one another, the volumes may be acquired as a set or individually.

Goals of the Book Overthelast thirty yearsthere has been arevolutionindiagnostic radiology as a result oftheemergenceofcomputerized tomography (CT), which is the process of obtaining the density distribution within the human body from multiple x-ray projections. Since an enormous variety of possible density values may occur in the body, a large number of projections are necessary to ensure the accurate reconstruction oftheir distribution. There are other situations in which we desire to reconstruct an object from its projections, but in which we know that the object to be recon structed has only a small number of possible values. For example, a large fraction of objects scanned in industrial CT (for the purpose of nonde structive testing or reverse engineering) are made of a single material and so the ideal reconstruction should contain only two values: zero for air and the value associated with the material composing the object. Similar as sumptions may even be made for some specific medical applications; for example, in angiography ofthe heart chambers the value is either zero (in dicating the absence of dye) or the value associated with the dye in the chamber. Another example arises in the electron microscopy of biological macromolecules, where we may assume that the object to be reconstructed is composed of ice, protein, and RNA. One can also apply electron mi croscopy to determine the presenceor absence ofatoms in crystallinestruc tures, which is again a two-valued situation."

This book provides structured up-to-date information on all routine protocols used for multislice (multidetector row) CT. The volume contains a detailed technical section and covers the prevailing investigations of the brain, neck, lungs and chest, abdomen with parenchymal organs and gastrointestinal tract, the musculoskeletal system and CTA as well as dedicated protocols for the heart. Separate chapters address the how-to of CT-guided interventions such as punctures, drainages, and therapeutic approaches. Each protocol is displayed en bloc, enabling rapid appreciation of indications and the necessary scanner settings.

The second edition includes contributions by renowned experts in the field, who not only provide their clinical experience on each topic, but also give guidelines for indications, workflow, postprocessing and reconstruction algorithms.

This book concisely reviews important advances in radiation oncology, providing practicing radiation oncologists with a fundamental understanding of each topic and an appreciation of its significance for the future of radiation oncology. It explores in detail the impact of newer imaging modalities, such as multiparametric magnetic resonance imaging (MRI) and positron emission tomography (PET) using fluorodeoxyglucose (FDG) and other novel agents, which deliver improved visualization of the physiologic and phenotypic features of a given cancer, helping oncologists to provide more targeted radiotherapy and assess the response. Due consideration is also given to how advanced technologies for radiation therapy delivery have created new treatment options for patients with localized and metastatic disease, highlighting the increasingly important role of image-guided radiotherapy in treating systemic and oligometastatic disease. Further topics include the potential value of radiotherapy in enhancing immunotherapy thanks to the broader immune-stimulatory effects, how cancer stem cells and the tumor microenvironment influence response, and the application of mathematical and systems biology methods to radiotherapy.

On-treatment verification imaging has developed rapidly in recent years and is now at the heart of image-guided radiation therapy (IGRT) and all aspects of radiotherapy planning and treatment delivery. This is the first book dedicated to just this important topic, which is written in an accessible manner for undergraduate and graduate therapeutic radiography (radiation therapist) students and trainee medical physicists and clinicians. The later sections of the book will also help established medical physicists, therapeutic radiographers, and radiation therapists familiarise themselves with developing and cutting-edge techniques in IGRT. Features: Clinically focused and internationally applicable; covering a wide range of topics related to on-treatment verification imaging for the study of IGRT Accompanied by a library of electronic teaching and assessment resources for further learning and understanding Authored by experts in the field with over 18 years' experience of pioneering the original forms of on-treatment verification imaging in radiotherapy (electronic portal imaging) in clinical practice, as well as substantial experience of teaching the techniques to trainees

This practical, two-volume handbook is the first to illustrate the use of transvaginal color doppler in obstetrics and gynecology. It provides a critical look at state-of-the-art ultrasound techniques and equipment and serves as a comprehensive reference with numerous black/white and color ultrasonograms, tables and graphs. The volumes include extensive literature citations which assist the investigator in finding more in-depth references. This work focuses on the recent remarkable expansion in both diagnostic techniques and clinical applications. It reports findings based on an unusually large patient population over a long period of time. It presents the accuracy and limitations of various aspects of ultrasound. This important publication is especially helpful for clinicians and researchers.

This practical, two volume handbook provides a critical look at state-of -the-art ultrasound techniques and equipment. It is a comprehensive reference with numerous black/white and color ultrasonograms, tables and graphs. The volumes include extensive literature citations which assist the investigator in finding more in-depth references. This work focuses on the recent remarkable expansion in both diagnostic techniques and clinical applications. It reports findings based on an unusually large patient population over al long time period. It presents the accuracy and limitations of various aspects of ultrasound.

This book explores the physics of CT dosimetry and provides practical guidance on best practice for medical researchers and practitioners. A rigorous description of the basic physics of CT dosimetry is presented and illustrates flaws of the current methodology. It also contains helpful (and rigorous) shortcuts to reduce the measurement workload for medical physicists. The mathematical rigor is accompanied by easily-understood physical explanations and numerous illustrative figures. Features: Authored by a recognised expert in the field and award-winning teacher Includes derivations for tube current modulation and variable pitch as well as stationary table techniques Explores abnormalities present in dose-tracking software based on CTDI and presents methods to correct them

The use of more robust, affordable, and efficient techniques and technologies in the application of medicine is presently a subject of huge interest and demand. Technology and Medical Sciences solidifies knowledge in the fields of technology and medical sciences and to define their key stakeholders. The book is designed for academics in engineering, mathematics, medicine, biomechanics, computation sciences, hardware development and manufacturing, electronics and instrumentation, and materials science.

Since radiologists learn by seeing, this book 's case-based format is ideal. The 102 cases unknown and 217 supplemental cases throughout depict scenarios encountered in daily practice, with emphasis on the growing area of sports injuries and traumatic disorders in older children and adolescents. The cases are illustrated with nearly 600 high-resolution MRI images, as well as complementary plain films, scintigrams, and CT scans. Each case outlines the clinical history, findings, and differential diagnosis. Clinical pearls, questions and answers, and concluding summaries are also included. An orthopedic surgeon provides commentary where appropriate to share the insight gained from sports medicine.

This scholarly set of well-harmonized volumes provides indispensable and complete coverage of the exciting and evolving subject of medical imaging systems. Leading experts on the international scene tackle the latest cutting-edge techniques and technologies in an in-depth but eminently clear and readable approach. Complementing and intersecting one another, each volume offers a comprehensive treatment of substantive importance to the subject areas. The chapters, in turn, address topics in a self-contained manner with authoritative introductions, useful summaries, and detailed reference lists. Extensively well-illustrated with figures throughout, the five volumes as a whole achieve a unique depth and breath of coverage. As a cohesive whole or independent of one another, the volumes may be acquired as a set or individually.

Interventional cardiology has transitioned from angiographic subjective analysis of stenosis severity into assessment of plaque characteristics and objective assessment of stenosis severity. The evolution of novel interventional imaging modalities is progressively altering our understanding of coronary artery disease diagnosis and prognosis. This book will be an essential companion to assist interventional cardiologists in better assessing patients with Coronary Artery Disease. It will encompass and review all interventional imaging modalities and provide guidance for interventional cardiologists to use these modalities.

Covering the entire spectrum of this fast-changing field, Diagnostic Imaging: Obstetrics, fourth edition, is an invaluable resource for radiologists, perinatologists, and trainees-anyone who requires an easily accessible, highly visual reference on today's obstetric imaging. Dr. Paula J. Woodward and a team of highly regarded experts provide up-to-date information on recent advances in technology and the understanding of fetal development and disease processes to help you make informed decisions at the point of care. The text is lavishly illustrated, delineated, and referenced, making it a useful learning tool as well as a handy reference for daily practice. Serves as a one-stop resource for key concepts and information on obstetric imaging, including a wealth of new material and content updates throughout Features more than 3,000 illustrations (grayscale, 3D, color, and pulsed-wave Doppler ultrasound; fetal MR; extensive clinical and/or pathologic correlation; and full-color illustrations) 1,300 additional digital images, and 175 new ultrasound video clips Features updates from cover to cover including new information on the genetic basis of fetal diseases, as well as new diagnoses and management protocols; additional and expanded differential diagnoses; and recent consensus guidelines and practice standards Covers dramatic new changes in technology, including recent innovations in 3D ultrasound and fetal MRI, as well as the earliest ultrasound findings seen with each condition due to improved ultrasound technology Reflects a multidisciplinary, collaborative approach to diagnosis, management, and treatment between radiologists, perinatologists, pediatricians, and surgeons Includes embryology and anatomy overview chapters, along with pertinent differential diagnoses for comprehensive coverage Uses bulleted, succinct text and highly templated chapters for quick comprehension of essential information at the point of care Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices

This scholarly set of well-harmonized volumes provides indispensable and complete coverage of the exciting and evolving subject of medical imaging systems. Leading experts on the international scene tackle the latest cutting-edge techniques and technologies in an in-depth but eminently clear and readable approach. Complementing and intersecting one another, each volume offers a comprehensive treatment of substantive importance to the subject areas. The chapters, in turn, address topics in a self-contained manner with authoritative introductions, useful summaries, and detailed reference lists. Extensively well-illustrated with figures throughout, the five volumes as a whole achieve a unique depth and breath of coverage. As a cohesive whole or independent of one another, the volumes may be acquired as a set or individually.

This scholarly set of well-harmonized volumes provides indispensable and complete coverage of the exciting and evolving subject of medical imaging systems. Leading experts on the international scene tackle the latest cutting-edge techniques and technologies in an in-depth but eminently clear and readable approach.Complementing and intersecting one another, each volume offers a comprehensive treatment of substantive importance to the subject areas. The chapters, in turn, address topics in a self-contained manner with authoritative introductions, useful summaries, and detailed reference lists. Extensively well-illustrated with figures throughout, the five volumes as a whole achieve a unique depth and breath of coverage.As a cohesive whole or independent of one another, the volumes may be acquired as a set or individually.

Combat Radiology provides unique insights into a military radiologist s role in the modern battlefield environment. Drawing on his recent experiences in Iraq, Col. Les Folio, a retired air force radiologist and flight surgeon with over twenty years of service, presents a comprehensive introduction to diagnostic imaging technology for the deployed military physician. Topics in the book include descriptions of imaging capabilities of hospitals in deployed military bases in combat zones; practical imaging techniques and terminology associated with penetrating/perforating blast and ballistic injuries; recent medical advances on the battlefield; and the changing role of imaging modalities in combat situations. Additionally, specific anatomic and pathologic imaging cases from combat situations are presented, including traumatic brain injury, chest, abdomen/pelvis, and skeletal trauma. Combat Radiology will appeal not only to military radiologists and surgeons, but also to civilian emergency radiologists and trauma physicians who encounter patients with ballistic and blast injuries resulting from armed conflict, terrorism, and disaster situations."