Goals of the Book Overthelast thirty yearsthere has been arevolutionindiagnostic radiology as a result oftheemergenceofcomputerized tomography (CT), which is the process of obtaining the density distribution within the human body from multiple x-ray projections. Since an enormous variety of possible density values may occur in the body, a large number of projections are necessary to ensure the accurate reconstruction oftheir distribution. There are other situations in which we desire to reconstruct an object from its projections, but in which we know that the object to be recon structed has only a small number of possible values. For example, a large fraction of objects scanned in industrial CT (for the purpose of nonde structive testing or reverse engineering) are made of a single material and so the ideal reconstruction should contain only two values: zero for air and the value associated with the material composing the object. Similar as sumptions may even be made for some specific medical applications; for example, in angiography ofthe heart chambers the value is either zero (in dicating the absence of dye) or the value associated with the dye in the chamber. Another example arises in the electron microscopy of biological macromolecules, where we may assume that the object to be reconstructed is composed of ice, protein, and RNA. One can also apply electron mi croscopy to determine the presenceor absence ofatoms in crystallinestruc tures, which is again a two-valued situation."

This book is about pulse nuclear magnetic resonance (NMR), with its techniques, the information to be obtained, and practical advice on performing experiments. The emphasis is on the motivation and physical ideas underlying NMR experiments and the actual techniques, including the hardware used. The level is generally suitable for those to whom pulse NMR is a new technique, be they students in chemistry or physics on the one hand and research workers in biology, geology, or agriculture, on the other. The book can be used for a senior or first year graduate course where it could supplement the standard NMR texts.

This book provides structured up-to-date information on all routine protocols used for multislice (multidetector row) CT. The volume contains a detailed technical section and covers the prevailing investigations of the brain, neck, lungs and chest, abdomen with parenchymal organs and gastrointestinal tract, the musculoskeletal system and CTA as well as dedicated protocols for the heart. Separate chapters address the how-to of CT-guided interventions such as punctures, drainages, and therapeutic approaches. Each protocol is displayed en bloc, enabling rapid appreciation of indications and the necessary scanner settings.

The second edition includes contributions by renowned experts in the field, who not only provide their clinical experience on each topic, but also give guidelines for indications, workflow, postprocessing and reconstruction algorithms.

This book explores the physics of CT dosimetry and provides practical guidance on best practice for medical researchers and practitioners. A rigorous description of the basic physics of CT dosimetry is presented and illustrates flaws of the current methodology. It also contains helpful (and rigorous) shortcuts to reduce the measurement workload for medical physicists. The mathematical rigor is accompanied by easily-understood physical explanations and numerous illustrative figures. Features: Authored by a recognised expert in the field and award-winning teacher Includes derivations for tube current modulation and variable pitch as well as stationary table techniques Explores abnormalities present in dose-tracking software based on CTDI and presents methods to correct them

This practical, two volume handbook provides a critical look at state-of -the-art ultrasound techniques and equipment. It is a comprehensive reference with numerous black/white and color ultrasonograms, tables and graphs. The volumes include extensive literature citations which assist the investigator in finding more in-depth references. This work focuses on the recent remarkable expansion in both diagnostic techniques and clinical applications. It reports findings based on an unusually large patient population over al long time period. It presents the accuracy and limitations of various aspects of ultrasound.

This book presents a vast collection of radiologic images of cases seen in a very busy emergency room. It encompasses common and very unusual pathology and every imaging modality. The book is divided into four parts on pathology of the vascular system, chest, abdomen and pelvis and reproductive organs. Images obtained with the modalities that best depict the abnormality in question are presented, with marking of the salient pathology and explanation of the abnormal imaging features in concise captions. Whenever possible, differential diagnosis is covered using further images and guidance is also provided on selection of additional modalities to confirm the diagnosis. The book will help residents to analyze different diseases and relate pathophysiology to imaging and assist students in appreciating what is abnormal. It will be a useful guide for the busy practicing radiologist and aid clinicians in understanding the complexity of these cases and delivering better focused treatment.p>

Developing an effective computer-aided diagnosis (CAD) system for lung cancer is of great clinical importance and can significantly increase the patient's chance for survival. For this reason, CAD systems for lung cancer have been investigated in a large number of research studies. A typical CAD system for lung cancer diagnosis is composed of four main processing steps: segmentation of the lung fields, detection of nodules inside the lung fields, segmentation of the detected nodules, and diagnosis of the nodules as benign or malignant. This book overviews the current state-of-the-art techniques that have been developed to implement each of these CAD processing steps. Overviews the latest state-of-the-art diagnostic CAD systems for lung cancer imaging and diagnosis Offers detailed coverage of 3D and 4D image segmentation Illustrates unique fully automated detection systems coupled with 4D Computed Tomography (CT) Written by authors who are world-class researchers in the biomedical imaging sciences Includes extensive references at the end of each chapter to enhance further study Ayman El-Baz is a professor, university scholar, and chair of the Bioengineering Department at the University of Louisville, Louisville, Kentucky. He earned his bachelor's and master's degrees in electrical engineering in 1997 and 2001, respectively. He earned his doctoral degree in electrical engineering from the University of Louisville in 2006. In 2009, he was named a Coulter Fellow for his contributions to the field of biomedical translational research. He has 17 years of hands-on experience in the fields of bio-imaging modeling and noninvasive computer-assisted diagnosis systems. He has authored or coauthored more than 500 technical articles (132 journals, 23 books, 57 book chapters, 211 refereed-conference papers, 137 abstracts, and 27 U.S. patents and disclosures). Jasjit S. Suri is an innovator, scientist, a visionary, an industrialist, and an internationally known world leader in biomedical engineering. He has spent over 25 years in the field of biomedical engineering/devices and its management. He received his doctorate from the University of Washington, Seattle, and his business management sciences degree from Weatherhead School of Management, Case Western Reserve University, Cleveland, Ohio. He was awarded the President's Gold Medal in 1980 and named a Fellow of the American Institute of Medical and Biological Engineering for his outstanding contributions in 2004. In 2018, he was awarded the Marquis Life Time Achievement Award for his outstanding contributions and dedication to medical imaging and its management.

This book introduces the latest optical coherence tomography (OCT) imaging and computerized automatic image analysis techniques, and their applications in the diagnosis and treatment of retinal diseases. Discussing the basic principles and the clinical applications of OCT imaging, OCT image preprocessing, as well as the automatic detection and quantitative analysis of retinal anatomy and pathology, it includes a wealth of clinical OCT images, and state-of-the-art research that applies novel image processing, pattern recognition and machine learning methods to real clinical data. It is a valuable resource for researchers in both medical image processing and ophthalmic imaging.

This book concisely reviews important advances in radiation oncology, providing practicing radiation oncologists with a fundamental understanding of each topic and an appreciation of its significance for the future of radiation oncology. It explores in detail the impact of newer imaging modalities, such as multiparametric magnetic resonance imaging (MRI) and positron emission tomography (PET) using fluorodeoxyglucose (FDG) and other novel agents, which deliver improved visualization of the physiologic and phenotypic features of a given cancer, helping oncologists to provide more targeted radiotherapy and assess the response. Due consideration is also given to how advanced technologies for radiation therapy delivery have created new treatment options for patients with localized and metastatic disease, highlighting the increasingly important role of image-guided radiotherapy in treating systemic and oligometastatic disease. Further topics include the potential value of radiotherapy in enhancing immunotherapy thanks to the broader immune-stimulatory effects, how cancer stem cells and the tumor microenvironment influence response, and the application of mathematical and systems biology methods to radiotherapy.

This scholarly set of well-harmonized volumes provides indispensable and complete coverage of the exciting and evolving subject of medical imaging systems. Leading experts on the international scene tackle the latest cutting-edge techniques and technologies in an in-depth but eminently clear and readable approach. Complementing and intersecting one another, each volume offers a comprehensive treatment of substantive importance to the subject areas. The chapters, in turn, address topics in a self-contained manner with authoritative introductions, useful summaries, and detailed reference lists. Extensively well-illustrated with figures throughout, the five volumes as a whole achieve a unique depth and breath of coverage. As a cohesive whole or independent of one another, the volumes may be acquired as a set or individually.

This practical, two-volume handbook is the first to illustrate the use of transvaginal color doppler in obstetrics and gynecology. It provides a critical look at state-of-the-art ultrasound techniques and equipment and serves as a comprehensive reference with numerous black/white and color ultrasonograms, tables and graphs. The volumes include extensive literature citations which assist the investigator in finding more in-depth references. This work focuses on the recent remarkable expansion in both diagnostic techniques and clinical applications. It reports findings based on an unusually large patient population over a long period of time. It presents the accuracy and limitations of various aspects of ultrasound. This important publication is especially helpful for clinicians and researchers.

This scholarly set of well-harmonized volumes provides indispensable and complete coverage of the exciting and evolving subject of medical imaging systems. Leading experts on the international scene tackle the latest cutting-edge techniques and technologies in an in-depth but eminently clear and readable approach. Complementing and intersecting one another, each volume offers a comprehensive treatment of substantive importance to the subject areas. The chapters, in turn, address topics in a self-contained manner with authoritative introductions, useful summaries, and detailed reference lists. Extensively well-illustrated with figures throughout, the five volumes as a whole achieve a unique depth and breath of coverage. As a cohesive whole or independent of one another, the volumes may be acquired as a set or individually.

Electrical neuroimaging is based on the analysis of brain electrical activity recorded from the human scalp with multichannel EEG. It offers enormous potential for the dynamic mapping of brain functions, and for the non-invasive diagnosis of neurological and psychiatric conditions. This authoritative reference gives a systematic overview of new electrical imaging methods, with a sound introduction to the basics of multichannel recording of EEG and event-related potential (ERP) data, as well as spatio-temporal analysis of the potential fields. The book enables researchers to measure valid data, select and apply appropriate analysis strategies, and avoid the most common mistakes when analyzing and interpreting EEG/ERP data. Importantly, it informs the research communities of the possibilities opened by these space-domain oriented approaches to the analysis of brain electrical activity, and of their potential to offer even more powerful diagnostic techniques when integrated with other clinically relevant data.

The use of more robust, affordable, and efficient techniques and technologies in the application of medicine is presently a subject of huge interest and demand. Technology and Medical Sciences solidifies knowledge in the fields of technology and medical sciences and to define their key stakeholders. The book is designed for academics in engineering, mathematics, medicine, biomechanics, computation sciences, hardware development and manufacturing, electronics and instrumentation, and materials science.

This scholarly set of well-harmonized volumes provides indispensable and complete coverage of the exciting and evolving subject of medical imaging systems. Leading experts on the international scene tackle the latest cutting-edge techniques and technologies in an in-depth but eminently clear and readable approach.Complementing and intersecting one another, each volume offers a comprehensive treatment of substantive importance to the subject areas. The chapters, in turn, address topics in a self-contained manner with authoritative introductions, useful summaries, and detailed reference lists. Extensively well-illustrated with figures throughout, the five volumes as a whole achieve a unique depth and breath of coverage.As a cohesive whole or independent of one another, the volumes may be acquired as a set or individually.

Interventional cardiology has transitioned from angiographic subjective analysis of stenosis severity into assessment of plaque characteristics and objective assessment of stenosis severity. The evolution of novel interventional imaging modalities is progressively altering our understanding of coronary artery disease diagnosis and prognosis. This book will be an essential companion to assist interventional cardiologists in better assessing patients with Coronary Artery Disease. It will encompass and review all interventional imaging modalities and provide guidance for interventional cardiologists to use these modalities.

Features Provides a comprehensive review of all aspects of skin cancer management. Edited by experts in the area, with interdisciplinary and international collaborators. Promotes a 'Bigger picture' approach to the topic with multidisciplinary insight.

Combat Radiology provides unique insights into a military radiologist s role in the modern battlefield environment. Drawing on his recent experiences in Iraq, Col. Les Folio, a retired air force radiologist and flight surgeon with over twenty years of service, presents a comprehensive introduction to diagnostic imaging technology for the deployed military physician. Topics in the book include descriptions of imaging capabilities of hospitals in deployed military bases in combat zones; practical imaging techniques and terminology associated with penetrating/perforating blast and ballistic injuries; recent medical advances on the battlefield; and the changing role of imaging modalities in combat situations. Additionally, specific anatomic and pathologic imaging cases from combat situations are presented, including traumatic brain injury, chest, abdomen/pelvis, and skeletal trauma. Combat Radiology will appeal not only to military radiologists and surgeons, but also to civilian emergency radiologists and trauma physicians who encounter patients with ballistic and blast injuries resulting from armed conflict, terrorism, and disaster situations."

Focusing on high-yield information, Breast Imaging: The Core Requisites, 4th Edition emphasizes the basics to help you establish a foundational understanding of breast imaging during rotations, prepare for the core and certifying exams, refresh your knowledge of key concepts, and learn strategies to provide "value-added" reports to referring clinicians. This completely rewritten and reorganized edition emphasizes the essential knowledge you need in an easy-to-read format, with thorough updates that cover new imaging modalities, the latest guidelines, and integration of physics information throughout. Emphasizes the essentials in a templated, quick-reference format that includes numerous outlines, tables, pearls, boxed material, and bulleted content for easy reading, reference, and recall. Helps you build and solidify core knowledge to prepare you for clinical practice with critical, up-to-date information on mammography, breast ultrasound, digital breast tomosynthesis, and breast MRIs, as well as special chapters on lymph node evaluation in breast imaging, augmented and reconstructed breast, and special populations in breast imaging. Features hundreds of high-quality images, including correlations of ultrasound, mammography, digital breast tomosynthesis and MRI. Published as part of the newly reimagined Core Requisites series, an update to the popular Requisites series aimed at radiology trainees and today's busy clinicians. An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.

This book aims to be a complete guide to diagnose, manage and treat rare lung diseases encountered by practising pulmonologists and trainees. It extensively covers the "more common" of the rare lung diseases, categorising them based on developmental lung anomalies in adults, airway disorders, diffuse parenchymal lung diseases, neoplasms, rare vascular disorders and other miscellaneous conditions. This comprehensive review facilitates the study and understanding of this complex and diverse set of disorders, focussing on differential diagnosis, evidence-based discussions of management algorithms, and thoughtful analysis of treatment options. Key Features: 1. Reviews multiple rare lung diseases, including ones acquired congenitally to be expressed in old age. 2. Enriched with case studies and illustrations, guides the respiratory physicians and trainees to devise an effective treatment plan. 3. Focuses on concerned investigations, with a section on role of new procedures in the management.

Soft tissue tumours are extremely common although difficult to understand due to a large number of sub-types, leading to a significant increase in their imaging in the last decade. This highly illustrated practical book provides a simplified, systematic approach to imaging, reporting and diagnosing these tumours. It covers all the modalities with emphasis on ultrasound and MRI, along with the newer techniques in these modalities. This concise guide to soft tissue lesions, will help clinicians to quickly understand the spectrum of tumours and identify the appropriate imaging techniques to best serve their patients. Key Features: * Provides guidance by international experts on various types of soft tissue tumours (benign, malignant and tumour mimics), their relevant imaging features to help suggest specific or differential diagnosis and when to biopsy and when to refer to specialist centres. * Proves to be an excellent resource for general and specialist radiologists, radiology trainees, sonographers, sarcoma surgeons and oncologists for day-to-day reporting. * Discusses the importance of proper imaging and biopsy of tumors and the implications of unplanned excisions in sarcoma.

This book highlights advances and prospects of a highly versatile and dynamic research field: Therapeutic ultrasound. Leading experts in the field describe a wide range of topics related to the development of therapeutic ultrasound (i.e., high intensity focused ultrasound, microbubble-assisted ultrasound drug delivery, low intensity pulsed ultrasound, ultrasound-sensitive nanocarriers), ranging from the biophysical concepts (i.e., tissue ablation, drug and gene delivery, neuromodulation) to therapeutic applications (i.e., chemotherapy, sonodynamic therapy, sonothrombolysis, immunotherapy, lithotripsy, vaccination). This book is an indispensable source of information for students, researchers and clinicians dealing with non-invasive image-guided ultrasound-based therapeutic interventions in the fields of oncology, neurology, cardiology and nephrology.

Experiments in Nuclear Science is an introductory-level laboratory manual providing hands-on opportunities for developing insights into the origins and properties of nuclear radiations, their interactions with matter, their detection and measurement, and their applications in the physical and life sciences. Based on experiments successfully performed by hundreds of students at Rutgers University and the University of Wisconsin, this manual can be used as a stand-alone volume or alongside a textbook such as Introduction to Nuclear Science by Jeff C. Bryan. Relevant to a range of courses Each of the 32 exercises includes an overview of the scientific phenomenon, instructions for conducting the experiments and recording the data, directions for analyzing the data and reporting the results, specific questions relating to the experiments, and several problems relating to the scientific phenomena being investigated. Validated for safety and pedagogy in the undergraduate instructional laboratory, the exercises can be used in an undergraduate course in nuclear science. Individual exercises can also be adopted to demonstrate fundamental principles in a general science course as well as introductory biology and chemistry courses. Making use of off-the-shelf instrumentation, these exercises can be performed in a conventional laboratory under the supervision of an experienced instructor. Applicable to numerous career fields Demonstrating fundamental principles, the concepts explored through these experiments are relevant to a host of career opportunities, including those in the health sciences, the nuclear power industry, regulatory agencies, and waste management services.

This book contains contributions from computational biomechanics specialists who present and exchange opinions on the opportunities for applying their techniques to computer-integrated medicine, including computer-aided surgery and diagnostic systems. Computational Biomechanics for Medicine collects peer-reviewed chapters from the annual Computational Biomechanics for Medicine Workshop, in conjunction with the Medical Image Computing and Computer Assisted Intervention [MICCAI] Society conference. The works are dedicated to research in the field of methods and applications of computational biomechanics to medical image analysis, image-guided surgery, surgical simulation, surgical intervention planning, disease diagnosis and prognosis, analysis of injury mechanisms, implant and prosthesis design, artificial organ design, and medical robotics. These chapters will appeal to a wide range of researchers and students within the fields of engineering and medicine, as well as those working in computational science.