This book chiefly addresses the analysis and design of geosynchronous synthetic aperture radar (GEO SAR) systems, focusing on the algorithms, analysis, methods used to compensate for ionospheric influences, and validation experiments for Global Navigation Satellite Systems (GNSS). Further, it investigates special problems in the GEO SAR context, such as curved trajectories, the Earth's rotation, the 'non-stop-and-go' model, high-order Doppler parameters, temporal-variant ionospheric errors etc. These studies can also be extended to SAR with very high resolution and long integration time. Given the breadth and depth of its coverage, scientists and engineers in SAR and advanced graduate students in related areas will greatly benefit from this book.

This book examines non-invasive, electrical-based methods for disease diagnosis and assessment of heart function. In particular, a formalized signal model is proposed since this offers several advantages over methods that rely on measured data alone. By using a formalized representation, the parameters of the signal model can be easily manipulated and/or modified, thus providing mechanisms that allow researchers to reproduce and control such signals. In addition, having such a formalized signal model makes it possible to develop computer tools that can be used for manipulating and understanding how signal changes result from various heart conditions, as well as for generating input signals for experimenting with and evaluating the performance of e.g. signal extraction methods. The work focuses on bioelectrical information, particularly electrical bio-impedance (EBI). Once the EBI has been measured, the corresponding signals have to be modelled for analysis. This requires a structured approach in order to move from real measured data to the model of the corresponding signals. This book proposes a generic framework for this procedure. It can be used as a guide for modelling impedance cardiography (ICG) and impedance respirography (IRG) signals, as well as for developing the corresponding bio-impedance signal simulator (BISS).

The current textbooks for specialists are too detailed. This book will be a handy pocket guide for trainee vascular radiologists, and will serve as an aide-memoire for senior vascular radiologists. Each procedure will be shown in its entirety. Rather than being a library purchase, this book will be a handy and accessible guide for quick reference aimed at clinical interventional radiologists in multidisciplinary staff rooms and angiography suites.

Traditional research methodologies in the human respiratory system have always been challenging due to their invasive nature. Recent advances in medical imaging and computational fluid dynamics (CFD) have accelerated this research. This book compiles and details recent advances in the modelling of the respiratory system for researchers, engineers, scientists, and health practitioners. It breaks down the complexities of this field and provides both students and scientists with an introduction and starting point to the physiology of the respiratory system, fluid dynamics and advanced CFD modeling tools. In addition to a brief introduction to the physics of the respiratory system and an overview of computational methods, the book contains best-practice guidelines for establishing high-quality computational models and simulations. Inspiration for new simulations can be gained through innovative case studies as well as hands-on practice using pre-made computational code. Last but not least, students and researchers are presented the latest biomedical research activities, and the computational visualizations will enhance their understanding of physiological functions of the respiratory system.

Volume 13: Pineal, Pituitary, and Spinal Tumors is organized in six sections, for convenience and quick access to critical information. Section I, Types of Tumors includes a chapter on molecular characterization of Embryonal tumors, a chapter on diagnosis of metastatic oligodendroglioma using fine-needle aspiration cytology, one covering intra-arterial chemotherapy of oligodendroglial tumors and another on the role of cyclooxygenase-2 in the development and growth of Schwannomas, and others, closing with a chapter on trigeminal neuralgia with cerebellopontine angle tumors. Section II, Diagnosis, includes two chapters on cell counting in histopathologic slides of tumors. Section III offers three chapters which discuss aspects of intraoperative ultrasonography. Section IV covers brain tumor surgery, and Section V surveys Brain Metastasis. The final section offers a wide-ranging review of General Diseases, with chapters on, among others, Alexander Disease; Lipoma; Transplantation of human umbilical cord blood mononuclear cells in cases of neonatal hypoxic-ischemic brain damage; and a chapter discussing the use of mobile phones and brain cancer risk in children. Like its twelve predecessors in the series, this volume merits distinction for its thorough approach, its roster of 78 distinguished contributors representing 14 different countries and its detailed examination of leading-edge technology and methods.

There have been many great advances in the field of biomedical imaging in recent years, with supramolecular chemistry playing a key role in the evolution of modern imaging techniques. Non-covalent supramolecular interactions are fundamental to countless biological processes, from host-guest binding to the stabilisation of complex structures. Supramolecular chemistry techniques can be employed to create probes that can be targeted to either exploit or disrupt these interactions, giving the potential for both diagnostic and therapeutic effects. Furthermore, in techniques such as contrast enhanced MRI, controlling the interactions between solvent molecules and the imaging agent is crucial to the development of the technique. With rapid growth in the synthesis and study of molecular imaging agents, the understanding of their associated techniques has sometimes lagged behind. Supramolecular Chemistry in Biomedical Imaging will fill this gap by clarifying the state of current understanding and the nature of the underlying problems inherent to addressing problems in biology. It will cover both the techniques used in imaging and the molecular and supramolecular systems used to exploit them. This publication targets academics coming to the field from mainstream supramolecular chemistry, research graduates and undergraduates interested in supramolecular chemistry, synthesis or imaging agents and imaging techniques for biomedical applications.

Are Amazon Alexa and Google Home limited to our bedrooms, or can they be used in hospitals? Do you envision a future where physicians work hand-in-hand with voice AI to revolutionize healthcare delivery? In the near future, clinical smart assistants will be able to automate many manual hospital tasks-and this will be only the beginning of the changes to come. Voice AI is the future of physician-machine interaction and this Focus book provides invaluable insight on its next frontier. It begins with a brief history and current implementations of voice-activated assistants and illustrates why clinical voice AI is at its inflection point. Next, it describes how the authors built the world's first smart surgical assistant using an off-the-shelf smart home device, outlining the implementation process in the operating room. From quantitative metrics to surgeons' feedback, the authors discuss the feasibility of this technology in the surgical setting. The book then provides an in-depth development guideline for engineers and clinicians desiring to develop their own smart surgical assistants. Lastly, the authors delve into their experiences in translating voice AI into the clinical setting and reflect on the challenges and merits of this pursuit. The world's first smart surgical assistant has not only reduced surgical time but eliminated major touch points in the operating room, resulting in positive, significant implications for patient outcomes and surgery costs. From clinicians eager for insight on the next digital health revolution to developers interested in building the next clinical voice AI, this book offers a guide for both audiences.

Within the field of neuroscience, the past few decades have witnessed an exponential growth of research into the brain mechanisms underlying both normal and pathological states of consciousness in humans. The development of sophisticated imaging techniques to visualize and map brain activity in vivo has opened new avenues in our understanding of the pathological processes involved in common neuropsychiatric disorders affecting consciousness, such as epilepsy, coma, vegetative states, dissociative disorders, and dementia. This book presents the state of the art in neuroimaging exploration of the brain correlates of the alterations in consciousness across these conditions, with a particular focus on the potential applications for diagnosis and management. Although the book has a practical approach and is primarily targeted at neurologists, neuroradiologists, and psychiatrists, it will also serve as an essential reference for a wide range of researchers and health care professionals.

This book presents non-linear image enhancement approaches to mammograms as a robust computer-aided analysis solution for the early detection of breast cancer, and provides a compendium of non-linear mammogram enhancement approaches: from the fundamentals to research challenges, practical implementations, validation, and advances in applications. The book includes a comprehensive discussion on breast cancer, mammography, breast anomalies, and computer-aided analysis of mammograms. It also addresses fundamental concepts of mammogram enhancement and associated challenges, and features a detailed review of various state-of-the-art approaches to the enhancement of mammographic images and emerging research gaps. Given its scope, the book offers a valuable asset for radiologists and medical experts (oncologists), as mammogram visualization can enhance the precision of their diagnostic analyses; and for researchers and engineers, as the analysis of non-linear filters is one of the most challenging research domains in image processing.

This book examines multi-quantum magnetic resonance imaging methods and the diagnostics of brain disorders. It consists of two Parts. The part I is initially devoted towards the basic concepts of the conventional single quantum MRI techniques. It is supplemented by the basic knowledge required to understand multi-quantum MRI. Practical illustrations are included both on recent developments in conventional MRI and the MQ-MRI. This is to illustrate the connection between theoretical concepts and their scope in the clinical applications. The Part II initially sets out the basic details about quadrupole charge distribution present in certain nuclei and their importance about the functions they perform in our brain. Some simplified final mathematical expressions are included to illustrate facts about the basic concepts of the quantum level interactions between magnetic dipole and the electric quadrupole behavior of useful nuclei present in the brain. Selected practical illustrations, from research and clinical practices are included to illustrate the newly emerging ideas and techniques. The reader should note that the two parts of the book are written with no interdependence. One can read them quite independently.

This is a practical guide to tomographic image reconstruction with projection data, with strong focus on Computed Tomography (CT) and Positron Emission Tomography (PET). Classic methods such as FBP, ART, SIRT, MLEM and OSEM are presented with modern and compact notation, with the main goal of guiding the reader from the comprehension of the mathematical background through a fast-route to real practice and computer implementation of the algorithms. Accompanied by example data sets, real ready-to-run Python toolsets and scripts and an overview the latest research in the field, this guide will be invaluable for graduate students and early-career researchers and scientists in medical physics and biomedical engineering who are beginners in the field of image reconstruction. A top-down guide from theory to practical implementation of PET and CT reconstruction methods, without sacrificing the rigor of mathematical background Accompanied by Python source code snippets, suggested exercises, and supplementary ready-to-run examples for readers to download from the CRC Press website Ideal for those willing to move their first steps on the real practice of image reconstruction, with modern scientific programming language and toolsets Daniele Panetta is a researcher at the Institute of Clinical Physiology of the Italian National Research Council (CNR-IFC) in Pisa. He earned his MSc degree in Physics in 2004 and specialisation diploma in Health Physics in 2008, both at the University of Pisa. From 2005 to 2007, he worked at the Department of Physics "E. Fermi" of the University of Pisa in the field of tomographic image reconstruction for small animal imaging micro-CT instrumentation. His current research at CNR-IFC has as its goal the identification of novel PET/CT imaging biomarkers for cardiovascular and metabolic diseases. In the field micro-CT imaging, his interests cover applications of three-dimensional morphometry of biosamples and scaffolds for regenerative medicine. He acts as reviewer for scientific journals in the field of Medical Imaging: Physics in Medicine and Biology, Medical Physics, Physica Medica, and others. Since 2012, he is adjunct professor in Medical Physics at the University of Pisa. Niccolo Camarlinghi is a researcher at the University of Pisa. He obtained his MSc in Physics in 2007 and his PhD in Applied Physics in 2012. He has been working in the field of Medical Physics since 2008 and his main research fields are medical image analysis and image reconstruction. He is involved in the development of clinical, pre-clinical PET and hadron therapy monitoring scanners. At the time of writing this book he was a lecturer at University of Pisa, teaching courses of life-sciences and medical physics laboratory. He regularly acts as a referee for the following journals: Medical Physics, Physics in Medicine and Biology, Transactions on Medical Imaging, Computers in Biology and Medicine, Physica Medica, EURASIP Journal on Image and Video Processing, Journal of Biomedical and Health Informatics.

Cover simple modelling approaches as well as full Monte Carlo simulation of x-ray tubes Bremsstrahlung and characteristic contributions to the spectrum are discussed in detail Learning is supported by free open-source software and an online repository of code.

For over 50 years, coronary angiography has been the mainstay of diagnosing and quantifying the extent of coronary artery disease. However appreciation of the inherent limitations of conventional angiography has led to a plethora of new imaging modalities, each with their relative strengths and potential pitfalls. Advances in these techniques have given clinicians, as well as researchers, an overwhelming amount of information and the need for thoughtful interpretation. This outstanding book provides a comprehensive overview of the current status of imaging of coronary atherosclerosis. Covering the wide variety of available imaging modalities, the book provides state-of-the-art knowledge from leading authorities in each area. In their discussion, the authors include both invasive and non-invasive modalities, including the gold standard coronary angiography, the growing field of IVUS, and novel techniques such as functional imaging, molecular imaging, and the integration of biomarkers. The key concepts and practical information given in this volume will provide the reader with the necessary understanding to choosing appropriate imaging studies and building confidence in their skill set with each.

"Ultrasound in Environmental Protection" focuses on one of the more significant developments in the subject - environmental remediation - providing an overview on both the fundamentals and applications of ultrasound in environmental protection, incorporating recent research and state-of-the-art information on the scientific basis, modes of use, and engineering developments.
A broad spectrum of topics are covered: reactor design, sonochemical pollutant degradation, integrated unltrasonic/ biological treatment, ultrasound in disinfection, leaching by ultrasound, and ultrasonically enhanced removal of suspended solids.
Ultrasound is generated and applied at frequencies from 20 kHz to several MHz. The physio-chemical parameters of the sonicated media, reactor design, applied intensity, and duration of sonication, dramatically influence the effects that can be achieved.
It is hoped that this compilation will contribute to a better understanding and further development of sonochemistry as a clean technology not only for environmental remediation but also more generally.
The foundation of this compilation was formed during a workshop that was held at the Technical University of Hamburg-Harburg, Germany, in March 1999. This was the first workshop to be devoted to 'Ultrasound in Environmental Engineering' and brought together experience and knowledge from a broad spectrum of disciplines including chemistry, biology, engineering, equipment manufacturing, and plant design.

Presenting ultrasound pathology from a clinical perspective, this unique resource discusses various pathologies that may be related to a patient's symptoms and features illustrations with ultrasound scans that demonstrate each pathology. Organized into four major sections - abdomen, obstetrics, gynecology, and superficial structures - each symptom is presented in its own chapter along with key terms, an introductory paragraph, a clinical scenario, discussions of pathologies, illustrations, and patient scenarios. Instructor resources are available; please contact your Elsevier sales representative for details. "This book covers a wide range of ultrasound examinations looking at the clinical question first. It is written for sonographers and student sonographers by two Academics and a sonographer. Because this book is written by American authors some terminology will be incorrect in the UK setting. [...] However, as long as the reader is aware of this, most Ultrasound Departments will find this a useful resource to have on their shelves and use for CPD." Reviewed by: Allison Harris, Clinical Co-Ordinator, City University London, Date: Oct 14 "I really like the design and clinical focus of this book and believe that it will stimulate critical thinking among its transatlantic target audience. For UK readers, though, I feel it has less appeal." Reviewed by: RAD Magazine Date: July 2014 Symptom-based presentation makes it easy for beginning and experienced sonographers to quickly find information related to the patient's symptom. Summary tables of differential diagnoses and sonographic findings provide you with a brief overview of all chapter material for quick reference. Clinical scenarios at the beginning of each chapter help you learn to apply information to the clinical setting. Case studies and discussion questions give you the opportunity to enhance your critical-thinking skills and measure your comprehension of material. Over 900 ultrasound images correlated to the pathology illustrate what you'll encounter in the clinical setting. Glossary helps you define important terminology. New chapters provide you with more complete coverage of the pathology sonographers encounter in practice. New case studies with critical-thinking questions set up realistic situations for you to use as a frame of reference. 600 updated images produced by the latest technology keep you on the cutting-edge of sonography. Instructor access to multiple-choice and image based test questions

Key Features * Sets the standard for training and competency of this emerging, yet scientifically approved non-invasive technique of ultrasound with all the essential information on how to perform ultrasound and interpret the images obtained. * Features clear and didactic images demonstrating echo findings in various situations along with videos of diaphragmatic ultrasound offering a unique "window" on mechanically ventilated patients, allowing to take important clinical decisions on ventilatory modes and assistance by pulmonologists, critical care specialists, thoracic surgeons, emergency medicine specialists as well as trainees. * Includes a chapter on pediatric ultrasound along with ultrasound of other respiratory muscles (i.e., intercostal and abdominal) which is emerging as a useful complementary tool.

The field of magnetic resonance imaging (MRI) has developed rapidly over the past decade, benefiting greatly from the newly developed framework of compressed sensing and its ability to drastically reduce MRI scan times. MRI: Physics, Image Reconstruction, and Analysis presents the latest research in MRI technology, emphasizing compressed sensing-based image reconstruction techniques. The book begins with a succinct introduction to the principles of MRI and then: Discusses the technology and applications of T1rho MRI Details the recovery of highly sampled functional MRIs Explains sparsity-based techniques for quantitative MRIs Describes multi-coil parallel MRI reconstruction techniques Examines off-line techniques in dynamic MRI reconstruction Explores advances in brain connectivity analysis using diffusion and functional MRIs Featuring chapters authored by field experts, MRI: Physics, Image Reconstruction, and Analysis delivers an authoritative and cutting-edge treatment of MRI reconstruction techniques. The book provides engineers, physicists, and graduate students with a comprehensive look at the state of the art of MRI.

This book describes in detail the physical and mathematical foundations of ultrasonic phased array measurements.The book uses linear systems theory to develop a comprehensive model of the signals and images that can be formed with phased arrays. Engineers working in the field of ultrasonic nondestructive evaluation (NDE) will find in this approach a wealth of information on how to design, optimize and interpret ultrasonic inspections with phased arrays. The fundamentals and models described in the book will also be of significant interest to other fields, including the medical ultrasound and seismology communities. A unique feature of this book is that it presents a unified theory of imaging with phased arrays that shows how common imaging methods such as the synthetic aperture focusing technique (SAFT), the total focusing method (TFM), and the physical optics far field inverse scattering (POFFIS) imaging method are all simplified versions of more fundamental and quantitative imaging approaches, called imaging measurement models.

To enhance learning, this book first describes the fundamentals of phased array systems using 2-D models, so that the complex 3-D cases normally found in practice can be more easily understood.In addition to giving a detailed discussion of phased array systems, Fundamentals of Ultrasonic Phased Arrays also provides MATLAB(r) functions and scripts, allowing the reader to conduct simulations of ultrasonic phased array transducers and phased array systems with the latest modeling technology."

This book describes the interaction of living matter with photons, neutrons, charged particles, electrons and ions. The authors are specialists in the field of radiation protection. The book synthesizes many years of experiments with external radiation exposure in the fields of dosimetry and radiation shielding in medical, industrial and research fields. It presents the basic physical concepts including dosimetry and offers a number of tools to be used by students, engineers and technicians to assess the radiological risk and the means to avoid them by calculating the appropriate shields. The theory of radiation interaction in matter is presented together with empirical formulas and abacus. Numerous numerical applications are treated to illustrate the different topics. The state of the art in radiation protection and dosimetry is presented in detail, especially in the field of simulation codes for external exposure to radiation, medical projects and advanced research. Moreover, important data spread in different up to date references are presented in this book. The book deals also with accelerators, X-rays facilities, sealed sources, dosimetry, Monte Carlo simulation and radiation regulation. Each chapter is split in two parts depending on the level of details the readers want to focus on. The first part, accessible to a large public, provides a lot of simple examples to help understanding the physics concepts under radiation external exposure. The second part, called "Additional Information" is not mandatory; it aims on explaining topics more deeply, often using mathematical formulations. The book treats fundamental radiometric and dosimetric quantities to describe the interaction in materials under the aspects of absorbed dose processes in tissues. Definitions and applications on limited and operational radiation protection quantities are given. An important aspect are practical engineering tools in industrial, medical and research domains. Source characterization and shielding design are addressed. Also more "exotic" topics, such as ultra intense laser and new generation accelerators, are treated. The state of the art is presented to help the reader to work with the book in a self-consistent way. The basic knowledge necessary to apply Monte Carlo methods in the field of radiation protection and dosimetry for external radiation exposure is provided. Coverage of topics such as variance reduction, pseudo-random number generation and statistic estimators make the book useful even to experienced Monte Carlo practitioners. Solved problems help the reader to understand the Monte Carlo process. The book is meant to be used by researchers, engineers and medical physicist. It is also valuable to technicians and students.

This extensively revised and updated second edition of a widely read classic presents the use of ultrasound in nondestructive evaluation (NDE) inspections. Retaining the first edition's use of wave propagation /scattering theory and linear system theory, this volume also adds significant new material including: the introduction of MATLAB (R) functions and scripts that evaluate key results involving beam propagation and scattering, flaw sizing, and the modeling of ultrasonic systems. elements of Gaussian beam theory and a multi-Gaussian ultrasonic beam model for bulk wave transducers. a new chapter on the connection between ultrasonic modeling and probability of detection (POD) and reliability models. new and improved derivations of ultrasonic measurement models. updated coverage of ultrasonic simulators that have been developed around the world. Students, engineers, and researchers working in the ultrasonic NDE field will find a wealth of information on the modeling of ultrasonic inspections and the fundamental ultrasonic experiments that support those models in this new edition.

The book is a developed history of the radiological sciences - covering the back-story to Roentgen's discovery, the discovery itself and immediate reception the early days of radiology leading to classical radiology (the pre-digital world). The 1970s as the 'golden decade' of radiology will be covered in detail, with the development of CT, MRI and modern interventional radiology. It will appeal to interested members of the public, to those working in the field, and to historians of medicine and science.

We have considered it to be a demanding assignment to provide a complete exposition dealing with the nature of radiation, its effects, and protection against it to workers in health-related activities. "Radiation" (and more precisely "ionizing radiation") is emitted by X-ray machines, nuclear reactors, and nuclear weapons, but also comes from natural sources to which we are all exposed. It would have been easier to deal with this subject area with the terminology and mathematics employed by specialists. However, although most of the potential readers probably have obtained further pertinent knowledge, we assume no more than a high school education in science and mathematics and the challenge was to provide maximum information within this constraint. This book contains five sections: (A) Radiation Physics, (B) Radiological Physics, (C) Radiation Biology, (D) Radiation Effects on Human Populations, and (E) Radiation Protection. Each section is preceded by a synopsis covering its essential features. It provides sufficient information to enable readers to obtain a general under standing of the subject of the section and an adequate background for comprehension of other sections. The more detailed presentation in the bulk of each section is followed by appendixes that generally contain more advanced topics. This scheme necessarily involves some repetition but permits a more flexible approach for readers who are especially interested in the contents of particular sections."

This book equips readers to understand a complex range of healthcare products that are used to diagnose, monitor, and treat diseases or medical conditions affecting humans. The first part of the book presents medical technologies such as medical information retrieval, tissue engineering techniques, 3D medical imaging, nanotechnology innovations in medicine, medical wireless sensor networks, and knowledge mining techniques in medicine. The second half of the book focuses on healthcare technologies including prediction hospital readmission risk, modeling e-health framework, personal Web in healthcare, security issues for medical records, and personalized services in healthcare. The contributors are leading world researchers who share their innovations, making this handbook the definitive resource on these topics. Handbook of Medical and Healthcare Technologies is intended for a wide audience including academicians, designers, developers, researchers and advanced-level students. It is also valuable for business managers, entrepreneurs, and investors within the medical and healthcare industries.

Apply all of the latest advances in imaging of the retina and posterior segment with Ryan's Retinal Imaging and Diagnostics. 12 chapters derived from the landmark reference Retina, 5th Edition offer the focused guidance you need to better understand, apply, and optimize new and emerging imaging technologies. "...recommended as an educational resource for retina fellowship trainees and retina specialists." Reviewed by Graefes Arch Clin Exp Ophthalmol, Nov 2014 Put the very latest diagnostic imaging methods to work in your practice, including optical coherence tomography (OCT), fluorescein angiography, indocyanine angiography, autofluorescence imaging, ophthalmic ultrasound, and more. Assess the effectiveness of the newest diagnostic technologies and approaches that are changing the management of retinal disease, including future imaging technologies which will soon become the standard. Benefit from the extensive knowledge and experience of esteemed editor and ophthalmologist, the late Dr. Stephen Ryan, as well as the truly global perspective of many other contributing world authorities.