For those who treat and diagnose liver disease, whether radiologists, emergency medical physicians, hepatologists, or sonographers, a clear understanding of the strict protocol needed to obtain accurate measurements is essential. Multiparametric Ultrasound for the Assessment of Diffuse Liver Disease offers a practical approach to liver shear wave elastography acquisition from globally recognized leaders in the field. It answers critical questions such as how to use each of the current techniques to best characterize your patients' liver disease, how to deal with the limitations of each of these techniques, and what to ask-and not to ask-of your devices and software. Presents an overview of conventional ultrasound findings in chronic liver disease and portal hypertension, and presents the basic concepts and protocols needed to measure liver stiffness and interpret liver stiffness values. Details clinical applications, artifacts, and guidelines of liver ultrasound elastography, including tips and tricks. Reviews the latest ultrasound techniques to assess liver steatosis and focal liver lesions, as well as the uses of new technologies of fat quantification and dispersion. An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.

This book acts as a primer for radiographers upon performing computed tomography (CT) examinations. The focus resides in radiation physics, radiobiology, anatomy, imaging protocols and image evaluation. It seeks to provide readers insight into the practical and innovative approaches within CT, backed up with key literature and examples in practice. Recent innovations and the importance of new technology to acquire enhanced quality remain a focal point. These are essential in understanding the importance of dose optimization, patient anatomy and common pathology observed. Patient care will remain central in this book, supported with a dedicated chapter discussing effective communication, patient education, informed consent, coupled with the assessment of laboratory results and vital signs. The editors draw from recent publications and clinical expertise, supported with the growing trend of technological advances utilized within the CT environment. Critically, this volume focuses on the role of CT for an array of audiences but, more specifically, undergraduate and postgraduate radiographers worldwide.

Reinforce your understanding of Hagen-Ansert's Textbook of Diagnostic Sonography, 9th Edition with this practical workbook! With chapters corresponding to the textbook, this study guide provides exercises allowing you to review, practice, and apply sonography concepts. Case studies offer opportunities to apply your knowledge to the clinical setting. Like the text, this edition of the workbook includes updated images and scans, in addition to content that reflects the newest curriculum standards. It's a useful review and an excellent preparation tool for national board examinations in diagnostic sonography! Review questions are presented in a variety of formats, including multiple-choice, matching, short answer, fill-in-the-blank, and labeling, with answers at the back of the book. Exercises in each chapter provide review and practice with terminology, anatomy, physiology, laboratory values, sonographic anatomy and technique, and pathology. Anatomy labeling activities test your ability to recognize anatomic structures in sonographic images. Review of key terms in each chapter allows you to test your knowledge of the terminology used in the textbook. Case studies include images from the textbook, testing your skills at identifying key anatomy and pathology and in interpreting sonographic findings. Content reviews include multiple-choice questions to test your knowledge of the four main content areas covered on ARDMS board exams: general sonography, pediatric, cardiovascular anatomy, and obstetrics and gynecology. NEW! Updated content keeps pace with the 9th edition of Textbook of Diagnostic Sonography, reflecting the newest curriculum standards and preparing you for the national board examinations. NEW! Updated images and scans reflect the latest advances in the field and help you prepare for boards and for clinicals.

"Molecular Imaging: Fundamentals and Applications" is a comprehensive monograph which describes not only the theory of the underlying algorithms and key technologies but also introduces a prototype system and its applications, bringing together theory, technology and applications. By explaining the basic concepts and principles of molecular imaging, imaging techniques, as well as research and applications in detail, the book provides both detailed theoretical background information and technical methods for researchers working in medical imaging and the life sciences. Clinical doctors and graduate students will also benefit from this book. Jie Tian is a professor at the Institute of Automation, Chinese Academy of Sciences, China.

This book covers all various research areas using nano systems in the field of bio nanotechnology to fight against cancer for diagnosis and therapy including drug delivery from fundamentals to advanced levels. Book has designed such a way that, anyone who is interested to understand, learn or start his/her research career in the field of bio nanotechnology in cancer, can use as a gateway to enter in to the field as well as a serious advanced researcher can use as the reference text book. Due to multidisciplinary nature of the subject, the book has written so that advanced undergraduate, graduate, postgraduate and researchers from different fields can follow and understand the subject very easily. Plenty of figures and art works are used to convey the idea visibly and effortlessly

Focal therapy is a promising option for selected patients who have localized low or intermediate-risk prostate cancer, providing a compelling alternative between active surveillance and radical therapies by targeting the index lesion and preserving as much tissue as possible. Numerous cohort studies have already investigated multiple focal techniques, such as cryotherapy, high-intensity focused ultrasound, brachytherapy, photodynamic therapy, laser therapy, irreversible electroporation and cyberknife methods, all of which have demonstrated positive oncological outcomes with 70 to 90 % negative follow-up biopsy. These various ablative techniques have produced only minor side-effects concerning urinary function, a low rate of erectile dysfunction, and have demonstrated a limited rectal toxicity. As a result, the primary end-point has now shifted and a new strategy needs to be established for patient follow-up and for defining treatment failure. Written by international experts in the field, this book is mainly focused on new techniques, all of which are amply illustrated. Technical Aspects of Focal Therapy in Localized Prostate Cancer will be of great practical value to all urologists and oncologists.

Master the critical physics content you need to know with this new title in the popular Case Review series. Imaging Physics Case Review offers a highly illustrated, case-based preparation for board review to help residents and recertifying radiologists succeed on exams and demonstrate a clinical understanding of physics, patient safety, and improvement of imaging accuracy and interpretation. Presents 150 high-yield case studies organized by level of difficulty, with multiple-choice questions, answers, and rationales that mimic the format of certification exams. Uses short, easily digestible chapters and high-quality illustrations for efficient, effective learning and exam preparation. Discusses current advances in all modalities, ensuring that your study is up-to-date and clinically useful. Covers today's key physics topics including radiation safety and methods to prevent patient harm; how to reduce artifacts; basics of radiation doses including dose reduction strategies; cardiac CT physics; advanced ultrasound techniques; and how to optimize image quality using physics principles. Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices

Machine Learning and Medical Imaging presents state-of- the-art machine learning methods in medical image analysis. It first summarizes cutting-edge machine learning algorithms in medical imaging, including not only classical probabilistic modeling and learning methods, but also recent breakthroughs in deep learning, sparse representation/coding, and big data hashing. In the second part leading research groups around the world present a wide spectrum of machine learning methods with application to different medical imaging modalities, clinical domains, and organs. The biomedical imaging modalities include ultrasound, magnetic resonance imaging (MRI), computed tomography (CT), histology, and microscopy images. The targeted organs span the lung, liver, brain, and prostate, while there is also a treatment of examining genetic associations. Machine Learning and Medical Imaging is an ideal reference for medical imaging researchers, industry scientists and engineers, advanced undergraduate and graduate students, and clinicians.

Spreading to every corner of the Earth, the COVID-19 virus has had an unparalleled impact on all aspects of our lives. This book explores in detail how the COVID-19 pandemic has affected clinical practice, education, and research in medical physics, and how colleagues on the frontline dealt with this unpredictable and unprecedented pandemic. It tackles key questions such as: How did medical physicists first respond to the situation? What innovative strategies were taken and how effective were they? How are medical physicists preparing for the future? There will be a focus on the different experiences of regional medical physicists and the responses and outlooks in clinical practice, education, and research in the affected continents, Asia-Pacific, the Middle East, Europe, Africa and North and Latin America. With over 91 contributors from 39 countries, this unique resource contains key perspectives from teams from each territory to ensure a global range of accounts. The collective opinion and wisdom from the major medical physics journal editors-in-chief are also explored, alongside how the pandemic has affected the quantity and quality of publications. Voices of early-career researchers and students of medical physics will be included, with narratives of their experiences coping with life during the pandemic. Lastly, communicating leadership in times of adversity is highlighted. This book will be a historic account of the impact of the COVID-19 virus on the field of medical physics. It will be an ideal reference for medical physicists, medical physics trainees and students, hospital administrators, regulators, and healthcare professionals allied with medical physics. Key features: The first book to cover the impact of COVID-19 on the field of medical physics Edited by two experts in the field, with chapter contributions from subject area specialists around the world Broad, global coverage, ranging from the impact on teaching, research, and publishing, with unique perspectives from journal editors and students and trainees

Retrograde Ureteroscopy: Handbook of Endourology contains five focused, review-oriented volumes that are ideal for students and clinicians looking for a comprehensive review rather than a whole course. Each volume is easily accessible through eBook format. Topics covered review both the endourological diagnosis and treatment of prostate, urethral, urinary bladder, upper urinary tract, and renal pathology, with all chapters describing the most recent techniques, reviewing the latest results, and analyzing the most modern technologies. In the past ten years, the field of endourology has expanded beyond the urinary tract to include all urologic, minimally-invasive surgical procedures. Recent advancements in robotic and laparoscopic bladder surgery make this one of the fastest moving fields in medicine. As current textbooks are too time-consuming for busy urologists or trainees who also need to learn other areas of urology, this collection provides a quick references with over 4000 images that are appropriate for fellows and those teaching in the field.

Management of bladder cancer provides a single, comprehensive reference source that incorporates all the latest information regarding bladder cancer. The text covers epidemiology and natural history of bladder cancer as well as latest findings regarding the genetics and molecular biology of the disease. Diagnostic and staging evaluation of both non-muscle invasive and invasive bladder cancer is discussed. The text incorporates chapters summarizing new findings regarding markers for the diagnosis of bladder cancer and new diagnostic techniques to enhance traditional methods such as cystoscopy. Risk stratified treatment of non muscle invasive bladder cancer including various approaches to intravesical therapy are reviewed. Current guideline based approaches to management and new data regarding diagnosis and prognostication of muscle invasive bladder cancer is analyzed and summarized. The application of chemotherapy for muscle invasive and advanced disease is discussed and the evidence based application of multimodality therapy highlighted. Finally, gaps in current knowledge and areas for future research are highlighted. Ongoing important clinical trials which could imminently yield significant new knowledge is discussed. Authored by experts in their respective fields, Management of Bladder Cancer will serve as a easy and complete reference source for clinicians, researchers, individuals in training, allied health professionals and medical students in the fields of Urology, Medical Oncology, Radiation Oncology, Basic and Translational Science and Epidemiology.

This book discusses important fundamentals of radiation safety with specific details on dose units, calculations, measuring, and biological effects of ionizing radiation. The author covers different exposure situations and their requirements, and relevant legislation and regulations governing radiation safety. The book also examines radioactive waste management, the transport of radioactive materials, emergency planning and preparedness and various examples of radiation protection programs for industrial, medical, and academic applications.

Are Amazon Alexa and Google Home limited to our bedrooms, or can they be used in hospitals? Do you envision a future where physicians work hand-in-hand with voice AI to revolutionize healthcare delivery? In the near future, clinical smart assistants will be able to automate many manual hospital tasks-and this will be only the beginning of the changes to come. Voice AI is the future of physician-machine interaction and this Focus book provides invaluable insight on its next frontier. It begins with a brief history and current implementations of voice-activated assistants and illustrates why clinical voice AI is at its inflection point. Next, it describes how the authors built the world's first smart surgical assistant using an off-the-shelf smart home device, outlining the implementation process in the operating room. From quantitative metrics to surgeons' feedback, the authors discuss the feasibility of this technology in the surgical setting. The book then provides an in-depth development guideline for engineers and clinicians desiring to develop their own smart surgical assistants. Lastly, the authors delve into their experiences in translating voice AI into the clinical setting and reflect on the challenges and merits of this pursuit. The world's first smart surgical assistant has not only reduced surgical time but eliminated major touch points in the operating room, resulting in positive, significant implications for patient outcomes and surgery costs. From clinicians eager for insight on the next digital health revolution to developers interested in building the next clinical voice AI, this book offers a guide for both audiences.

Diffusion weighted imaging (DWI) is a key emerging imaging modality for the management of patients with possible breast lesions, and Diffusion MRI of the Breast is the first book to focus on all aspects of DWI in today's practice. It covers the knowledge necessary to undertake clinical breast DWI, with a thorough review of how DWI is currently used as a breast imaging modality and how breast lesions appear on DWI. Expert clinicians and physicists from around the world share their knowledge and expertise on everything from technical requirements and image analysis to clinical applications of DWI (diagnosis, prognosis, treatment monitoring) with case examples, and upcoming developments in the field (radiomics, AI). Offers an in-depth discussion of DWI's clinical applications in breast imaging, including the position of DWI with respect to other modalities, the use of DWI in the diagnosis of suspicious lesions with a multiparametric protocol, the use of DWI as an imaging biomarker of prognosis and response prediction, the potential role of DWI for unenhanced breast MR screening, and more. Provides a basic introduction to DWI before discussing a practical approach to clinical interpretation and quality assurance issues. Covers specific challenges and advanced techniques (IVIM, non-Gaussian diffusion, DTI, and other novel techniques), radiomics and artificial intelligence, and different vendor approaches in breast DWI packages. Features more than 500 high-quality images throughout. Explains how DWI could be specifically used to provide information on prognosis and prediction factors. Evaluates the current status of DWI, its potential for the management of breast cancer patients, and possible future developments in the field. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Now a routine tool in biomedical and life science research, live cell imaging has made major progress enabling this core biochemical, cell, and molecular biology technique to become even more powerful, versatile, and affordable. In Live Cell Imaging: Methods and Protocols, a panel of expert contributors provide a comprehensive compendium of experimental approaches to live cell imaging in the form of several overview chapters followed by representative examples and case studies covering different aspects of the most current methodology. By examining a range of state-of-the-art protocols extensively validated in complex biological studies, this volume highlights new experimental and instrumental opportunities and helps researchers to select appropriate imaging methods for their specific biological questions and measurement tasks. Written in the highly successful Methods in Molecular BiologyT series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Live Cell Imaging: Methods and Protocols promises to contribute greatly to the further development and dissemination of this fundamentally important technology which spans across many disciplines including molecular and cell biology, chemistry, physics, optics, engineering, cell physiology, and medicine. Written for: Molecular and cellular biologists, chemists, physicists, optics specialists, engineers, cell physiologists, and medical doctors

This book provides current, comprehensive, and clear explanations of the physics behind medical and biomedical applications of shock waves. Extracorporeal shock wave lithotripsy is one of the greatest medical advances of our time, and its techniques and clinical devices are continuously evolving. Further research continues to improve the understanding of calculi fragmentation and tissue-damaging mechanisms. Shock waves are also used in orthopedics and traumatology. Possible applications in oncology, cardiology, dentistry, gene therapy, cell transfection, transformation of fungi and bacteria, as well as the inactivation of microorganisms are promising approaches for clinical treatment, industrial applications and research. Medical and Biomedical Applications of Shock Waves is useful as a guide for students, technicians and researchers working in universities and laboratories. Chemists, biologists, physicians and veterinarians, involved in research or clinical practice will find useful advice, but also engineers and physicists may benefit from the overview of current research endeavors and future directions. Furthermore, it may also serve to direct manufacturers towards the design of more efficient and safer clinical, industrial and laboratory equipment.

"Cardiac MRI in Diagnosis, Clinical Management and Prognosis of Arrythmogenic Right Ventricular Dysplasia/Cardiomyopathy" provides up-to-date information regarding the most effective diagnostic protocols and CMR sequences for the evaluation of patients with suspected or known ARVC. It includes CMR protocol summaries and clinical algorithms presented as flow diagrams, many of which have never been previously published. The book contains case reports from the practice and database of Dr. Frank I. Marcus, world renowned ARVD expert; as well as input from imaging experts from a large academic center with unique RV pathology imaging experience. This title is the perfect pocket companion for cardiologists, pediatric cardiologists, cardiac imaging and electrophysiology specialists as well as cardiology researchers.
The only comprehensive MRI reference focused and dedicated on the utilization of MRI in screening, diagnosis, therapeutic guidance and prognostic assessment of ARVC.Provides evidence based diagnostic and prognostic algorithms for management of patients with known and suspected ARVC.Contains concise clinical CMR acquisition protocol and evidence-based summaries of recommendations and multiple practical tips and tricks shared by experts in the field.Includes practical guidelines helping to determine pre-test and post-test likelihood of ARVC; as well as CMR evidence of the disease progression.Accompanying website provides complementary videos important for the understanding of ARVC diagnosis.

This issue of Dental Clinics of North America focuses on Oral and Maxillofacial Radiology: Radiographic Interpretation and Diagnostic Strategies. Articles will include: Oral and maxillofacial imaging, Developmental disorders affecting jaws, Periodontal diseases, Temporomandibular joint disorders and orofacial pain, Benign jaw lesions, Malignant jaw lesions, Benign fibro-osseous lesions of jaws, Granulomatous diseases affecting jaws, Systemic diseases and conditions affecting jaws, Chemical and radiation associated jaw lesions, and more!

This book covers the most recent advances in using nanoparticles for biomedical imaging, including magnetic resonance imaging (MRI), magnetic particle imaging (MPI), nuclear medicine, ultrasound (US) imaging, computed tomography (CT), and optical imaging. Topics include nanoparticles for MRI and MPI, siRNA delivery, theranostic nanoparticles for PET imaging of drug delivery, US nanoparticles for imaging drug delivery, inorganic nanoparticles for targeted CT imaging, and quantum dots for optical imaging. This book serves as a valuable resource for the fundamental science of diagnostic nanoparticles and their interactions with biological targets, providing a practical handbook for improved detection of disease and its clinical implementation.

This book critically assesses the current state of knowledge on new and important detection technologies, e.g. mass spectrometry, tandem mass spectrometry, biosensor detection and tissue imaging, in connection with toxic chemical and biological agents. In general, the main topics discussed concern the risks and consequences of chemical and biological agents for human health in general, with special emphasis on all biochemical and metabolic pathways including the reproductive system. The exposome, genetic risks and the environment, various health hazard agents, risk assessment, environmental assessment and preparedness, and analysis of sub-lethal effects at the molecular level are also discussed. In closing, the book provides comprehensive information on the diagnosis of exposure, and on health concerns related to toxic chemical and biological agents.

This text presents a basic guide of the principles and applications of ultrasound in the critical care setting. The text also addresses the basic and clinical uses of ultrasound, including clinical cases at the end of each of the 7 sections of the clinical subdivisions. The final chapters focus on the issues of training, certification, credentialing and billing. These discussions make the text unique, as literature regarding monetary and training issues for ultrasound in the ICU is sparse. Each chapter is written by experts in the field, and supplemented with illustrations and links to videos of actual ultrasound examinations in patients. Ultrasonography in the ICU: Practical Applications will be of great utility to critical care specialists in the disciplines of surgery, medicine, anesthesiology and emergency medicine. In addition this book can be used as a teaching tool for critical care fellows and residents interested in further training in ultrasound for the critically ill patient.

Glaucoma is the second leading cause of blindness globally. Early detection and treatment can prevent its progression to avoid total blindness. This book discusses and reviews current approaches for detection and examines new approaches for diagnosing glaucoma using CAD system. Computer-Aided Glaucoma Diagnosis System, Chapter 1 provides a brief introduction of the disease and current methodology used to diagnose it today. Chapter 2 presents a review of the medical background of the disease, followed by a theoretical and mathematical background used in fundus image processing. Chapter 3 is a literature review about segmentation and feature extraction. Chapter 4 describes the formulation of the proposed methodology. In Chapter 5, the results of optic disc and optic cup segmentation algorithm are presented, the feature extraction and selection method, experimental results and performance evaluations of the classifier are given. Chapter 6 presents the conclusions and discussion of the future potential for the diagnostic system. This book is intended for biomedical engineers, computer science students, ophthalmologists and radiologists looking to develop a reliable automated computer-aided diagnosis system (CAD) for detecting glaucoma and improve diagnosis of the disease. Key Features Discusses a reliable automated computer-aided diagnosis system (CAD) for detecting glaucoma and presents an algorithm that detects optic disc and optic cup Assists ophthalmologists and researchers to test a new diagnostic method that reduces the effort and time of the doctors and cost to the patients Discusses techniques to reduce human error and minimize the miss detection rate and facilitate early diagnosis and treatment Presents algorithms to detect cup and disc color, shape features and RNFL texture features Dr. Arwa Ahmed Gasm Elseid is an assistant professor, Department of Biomedical Engineering, Sudan University of Science and Technology, Khartoum, Sudan. Dr. Alnazier Osman Mohammed Hamza is professor of Medical Imaging, College of Engineering, Sudan University of Sciences and Technology, Khartoum, Sudan.

The application of optical methods for investigating neocortical circuit dynamics has greatly expanded in recent years, providing novel insights into the fascinating world of brain function. Optical Imaging of Neocortical Dynamics presents a guide to these indispensible tools, which cover a broad range of spatiotemporal scales and a large variety of signaling aspects, ranging from voltage changes to metabolic states. This detailed volume specifically explores methods that are applied in experiments on living brains (in vivo) and that relate to functional properties on the spatial scale of cortical circuits. Beginning with an introductory section that focuses on physical fundamentals of optical imaging as well as molecular tools used for in vivo optical imaging and optogenetic control, the book continues with the most relevant methods and their applications to investigate changes in neuronal and glial activity states as well as optical imaging methods probing metabolic states. Written for the Neuromethods series, this volume contains the kind of detail and key implementation advice that ensures successful results in the lab. Practical and easy to use, Optical Imaging of Neocortical Dynamics serves as an ideal guide for researchers who aim to apply these highly valuable tools to their own neuroscientific studies.