This book highlights progress in terms of Virus Biology and Infection Detection, Prevention, and Control, along with Screening, Testing, and Detection Techniques, that will provide learners and researchers (from basic to advanced) with the most innovative computer-driven methodologies for the fight against COVID-19. In addition, this book also covers the Pre- and Post-Impact of the COVID-19 Pandemic Crisis that will definitely provide useful content for researchers to think broadly about the analytical areas affected by COVID-19. This ultimately shows different paths to the same destination to help understand the nature of the COVID-19 pandemic and how to avoid it in the future.

Stem Cell Labeling for Delivery and Tracking Using Noninvasive Imaging provides a comprehensive overview of cell therapy imaging, ranging from the basic biology of cell therapeutic choices to the preclinical and clinical applications of cell therapy. It emphasizes the use of medical imaging for therapeutic delivery/targeting, cell tracking, and determining therapeutic efficacy. The book first presents background information and insight on the major classes of stem and progenitor cells. It then describes the main imaging modalities and state-of-the-art techniques that are currently employed for stem cell tracking. In the final chapters, leading scholars offer clinical perspectives on existing and potential uses of stem cells as well as the impact of image-guided delivery and tracking in major organ systems. Through clear descriptions and color images, this volume illustrates how noninvasive imaging is used to track stem cells as they repair damaged tissue in the body. With contributions from some of the most prominent preclinical and clinical researchers in the field, the book helps readers to understand the evolving concepts of stem cell labeling and tracking as the field continues to move forward.

Informatics in Medical Imaging provides a comprehensive survey of the field of medical imaging informatics. In addition to radiology, it also addresses other specialties such as pathology, cardiology, dermatology, and surgery, which have adopted the use of digital images. The book discusses basic imaging informatics protocols, picture archiving and communication systems, and the electronic medical record. It details key instrumentation and data mining technologies used in medical imaging informatics as well as practical operational issues, such as procurement, maintenance, teleradiology, and ethics.

Highlights

• Introduces the basic ideas of imaging informatics, the terms used, and how data are represented and transmitted
• Emphasizes the fundamental communication paradigms: HL7, DICOM, and IHE
• Describes information systems that are typically used within imaging departments: orders and result systems, acquisition systems, reporting systems, archives, and information-display systems
• Outlines the principal components of modern computing, networks, and storage systems
• Covers the technology and principles of display and acquisition detectors, and rounds out with a discussion of other key computer technologies
• Discusses procurement and maintenance issues; ethics and its relationship to government initiatives like HIPAA; and constructs beyond radiology

The technologies of medical imaging and radiation therapy are so complex and computer-driven that it is difficult for physicians and technologists responsible for their clinical use to know exactly what is happening at the point of care. Medical physicists are best equipped to understand the technologies and their applications, and these individuals are assuming greater responsibilities in the clinical arena to ensure that intended care is delivered in a safe and effective manner. Built on a foundation of classic and cutting-edge research, Informatics in Medical Imaging supports and updates medical physicists functioning at the intersection of radiology and radiation.

Propelling quantitative MRI techniques from bench to bedside, Quantitative MRI in Cancer presents a range of quantitative MRI methods for assessing tumor biology. It includes biophysical and theoretical explanations of the most relevant MRI techniques as well as examples of these techniques in cancer applications.

The introductory part of the book covers basic cancer biology, theoretical aspects of NMR/MRI physics, and the hardware required to form MR images. Forming the core of the book, the next three parts illustrate how to characterize tissue properties with endogenous and exogenous contrast mechanisms and discuss common image processing techniques relevant for cancer. The final part explores emerging areas of MR cancer characterization, including radiation therapy planning, cellular and molecular imaging, pH imaging, and hyperpolarized MR. Each of the post-introductory chapters describes the salient qualitative and quantitative aspects of the techniques before proceeding to preclinical and clinical applications. Each chapter also contains references for further study.

Leading the way toward more personalized medicine, this text brings together existing and emerging quantitative MRI techniques for assessing cancer. It provides a self-contained overview of the theoretical and experimental essentials and state of the art in cancer MRI.

This text provides a comprehensive review of ERCP and EUS and the clinical conditions for which they are employed. Presented in a case-based format with accompanying videos, it will serve as a valuable practical clinical resource for gastroenterologists with an interest in ERCP and EUS. The text highlights major techniques involved in ERCP, reviews complications and recent data on preventing post-ERCP pancreatitis, and discusses important issues in training in ERCP including use of endoscopic simulators and assessment of competency as emphasized in the new ACGME guidelines. For biliary diseases, new techniques for managing biliary stones, novel technologies for diagnosing indeterminate biliary strictures, and new devices for treating benign and malignant strictures are also highlighted. For pancreatic diseases, advances in minimally invasive endoscopic techniques for pancreatic stones and strictures, and management of the complications of pancreatitis are reviewed. Furthermore, ERCP is not limited by age, pregnancy or history of abdominal surgeries and special considerations particular to these patient populations are also discussed. The EUS chapters review the breadth of equipment available for performing EUS and EUS-FNA, detail the technique of performing EUS-FNA, and explore pertinent issues with training and assessing competency analogous to ERCP training. Valuable insights on the basics of cytopathology relevant to the endosonographer are summarized. The classic indication for EUS of staging luminal cancers is examined in detail while pancreaticobiliary indications are discussed highlighting newer adjunctive technologies including elastography and contrast-enhanced EUS. Although in its infancy, the brave new world of therapeutic EUS is explored with a focus on endoscopic necrosectomy, EUS-guided biliary and pancreatic access as well as the exciting possibilities of EUS-guided radiofrequency ablation and injection of anti-tumor agents. ERCP and EUS: A Case Based Approach will serve as a very useful resource for physicians who perform or refer patients for ERCP and EUS. It provides a concise yet comprehensive summary of the current status of ERCP and EUS that will help guide patient management and stimulate clinical research.

Diagnostic Imaging for the Emergency Physician, written and edited by a practicing emergency physician for emergency physicians, takes a step-by-step approach to the selection and interpretation of commonly ordered diagnostic imaging tests. Dr. Joshua Broder presents validated clinical decision rules, describes time-efficient approaches for the emergency physician to identify critical radiographic findings that impact clinical management and discusses hot topics such as radiation risks, oral and IV contrast in abdominal CT, MRI versus CT for occult hip injury, and more. Diagnostic Imaging for the Emergency Physician was awarded a 2011 PROSE Award for Excellence for the best new publication in Clinical Medicine. Access the fully searchable text online at Expert Consult, along with downloadable images suitable for use in educational presentations. Choose the best test for each indication through clear explanations of the "how" and "why" behind emergency imaging. Interpret head, spine, chest, and abdominal CT images using a detailed and efficient approach to time-sensitive emergency findings. Stay on top of current developments in the field, including evidence-based analysis of tough controversies - such as indications for oral and IV contrast in abdominal CT and MRI versus CT for occult hip injury; high-risk pathology that can be missed by routine diagnostic imaging - including subarachnoid hemorrhage, bowel injury, mesenteric ischemia, and scaphoid fractures; radiation risks of diagnostic imaging - with practical summaries balancing the need for emergency diagnosis against long-terms risks; and more. Optimize diagnosis through evidence-based guidelines that assist you in discussions with radiologists, coverage of the limits of "negative" or "normal" imaging studies for safe discharge, indications for contrast, and validated clinical decision rules that allow reduced use of diagnostic imaging. Clearly recognize findings and anatomy on radiographs for all major diagnostic modalities used in emergency medicine from more than 1000 images. Find information quickly and easily with streamlined content specific to emergency medicine written and edited by an emergency physician and organized by body system. The "must-have" resource for emergency physicians to make critical diagnostic imaging decisions.

The second edition of this easy-to-understand pocket guide remains an invaluable tool for students, assistant practitioners and radiographers. Providing an accessible introduction to the subject in a reader-friendly format, it includes diagrams and photographs to support the text. Each chapter provides clear learning objectives and a series of MCQs to test reader assimilation of the material. The book opens with overviews of image production, basic mathematics and imaging physics, followed by detailed chapters on the physics relevant to producing diagnostic images using X-rays and digital technologies. The content has been updated throughout and includes a new chapter on CT imaging and additional material on radioactivity, dosimetry, and imaging display and manipulation. Clark's Essential Physics in Imaging for Radiographers supports students in demonstrating an understanding of the fundamental definitions of physics applied to radiography ... all you need to know to pass your exams!

First published in 1991, this book covers three major areas essential to in vivo biochemical studies with PET and SPECT: synthesis of radiopharmaceuticals, biological modeling, and clinical applications. The book emphasizes advances in the synthesis of radiopharmaceuticals used in PET and SPECT studies of brain flow and oxidatative metabolism, in addition to biological modeling. The most widely used 2-deoxyglucose/2-fluorodeoxyglucose models are discussed, as well as models used in the quantitation of brain receptors. Other topics include a possible model for converting 6-[18F] fluorodopa images into the quantitative rate of dopamine synthesis, evaluations of technetium- and iodine-labeled blood flow tracers, and possibilities for using SPECT to measure other pathophysiological variables. This book will be a valuable reference source to students and specialists interested in these in vivo measurements.

This issue reviews the latest advances in imaging of cartilage using MRI. ?A basis for understanding cartilage is provided in articles on normal anatomic appearance, morphology, and physiology. ?MR imaging of cartilage in specific joints such as knees and ankles, hip, and upper extremity are reviewed in separate articles, and assessment of rheumatoid conditions and cartilage repair are also covered.

Endocrine imaging is covered extensively in this issue of Radiologic Clinics. Articles will include: Thyroid Ultrasound, Part 1: Technique and Diffuse Disease; Thyroid Ultrasonography, Part 2: Nodules; Thyroid: Nuclear Medicine Update; Thyroid Cytology: Challenges in the Pursuit of Low-Grade Malignancies; Diagnosis and Treatment of Differentiated Thyroid Carcinoma; Thyroid Carcinoma: The Surgeon's Perspective; Imaging Surveillance of Differentiated Thyroid Cancer; Parathyroid Imaging; Adrenal Imaging: From Addison to Algorithms; Imaging of Neuroendocrine Tumors; Imaging of the Pituitary, and more!

This is the first book that presents a comprehensive introduction to and overview of electro-magnetic tissue property imaging techniques using MRI, focusing on Magnetic Resonance Electrical Impedance Tomography (MREIT), Electrical Properties Tomography (EPT) and Quantitative Susceptibility Mapping (QSM). The contrast information from these novel imaging modalities is unique since there is currently no other method to reconstruct high-resolution images of the electro-magnetic tissue properties including electrical conductivity, permittivity, and magnetic susceptibility. These three imaging modalities are based on Maxwell's equations and MRI data acquisition techniques. They are expanding MRI's ability to provide new contrast information on tissue structures and functions.To facilitate further technical progress, the book provides in-depth descriptions of the most updated research outcomes, including underlying physics, mathematical theories and models, measurement techniques, computation issues, and other challenging problems.

PET and SPECT imaging has improved to such a level that they are opening up exciting new horizons in medical diagnosis and treatment. This book provides a complete introduction to fundamentals and the latest progress in the field, including an overview of new scintillator materials and innovations in photodetector development, as well as the latest system designs and image reconstruction algorithms. It begins with basics of PET and SPECT physics, followed by technology advances and computing methods, quantitative techniques, multimodality imaging, instrumentation, pre-clinical and clinical imaging applications.

Principles and Applications of Therapeutic Ultrasound in Healthcare introduces concepts, principles, construction, and applications of therapeutic ultrasound: from bench to bedside. A comprehensive examination of the industry and medical application of ultrasound therapy, this book highlights working principles, research progress, and system structures of therapeutic ultrasound. It describes the principles of therapeutic ultrasound, details the system construction, introduces current and emerging applications, and discusses developing therapeutic ultrasound technologies. Divided into two parts, the book first introduces the fundamentals of biomedical acoustics, discusses ultrasound calibration methods, and the structures of available therapeutic ultrasound systems before moving on to the various applications of ultrasound therapy used in clinics. It includes a variety of extensive clinical trials, outcome photos and illustrating figures, and a critical commentary on the challenges in this field. The author discusses topics that include: The derivation of wave equation The mathematical solution of the wave propagation The phenomena of reflection Refraction and transmission in the acoustic field from different acoustic sources The radiation pattern of the ultrasound transducer The acoustical properties of biological tissues Ultrasound-induced bioeffects Cavitation The design of the ultrasound transducer The characterization method of the produced acoustic field An easy reference offering full coverage of popular ultrasound therapies, Principles and Applications of Therapeutic Ultrasound in Healthcare provides a simple explanation of fundamental acoustics, including wave equation, propagation, nonlinearity, and transducer design. It also discusses other potential applications, and is geared toward academia, industry, and researchers.

Practitioners of forensic medicine have various tools at their disposal to determine cause of death, and today's computed tomography (CT) can provide valuable clues if images are interpreted properly. Forensic Pathology of Fractures and Mechanisms of Injury: Postmortem CT Scanning is a guide for the forensic pathologist who wants to use CT imaging to assist in determining the mechanism of injury that might have contributed to death. Advice from a forensic pathologist using CT images in daily practice Drawn from the author's work at the Victorian Institute of Forensic Medicine, the book presents an overview of his experience with CT in routine casework, provides an appraisal of the literature with respect to fractures, and offers suggestions for the evaluation of CT images by pathologists. He then suggests what reasonable conclusions can be drawn from the images, the circumstances surrounding the death, and an external examination of the deceased. Includes images and case studies Enhanced with hundreds of CT images that clarify the text and case studies to put the material in context, the book begins by discussing classification of injuries and different types of fractures. It then explores the basics of CT. Next, the book gives a head-to-toe catalogue of various injuries and how they are represented on a CT scan. Finally, the book explores the use of CT in difficult forensic cases such as decomposed and burnt remains, falls, child abuse, and transportation incidents. While not intended to make a forensic pathologist an expert at CT image interpretation, the book enables these professionals to become familiar with the technology so they can competently use it in their practice, heightening the accuracy of their cause of death determinations.

This issue presents the use of PET imaging in the diagnosis, staging, and follow up of melanoma. Differentiation of early versus advanced stages of melanomaare reviewed in separate articles. As with other forms of cancer, assessing response to treatment is essential as well monitoring for recurrence. The issue also provides a glimpse into the future through a review of newer radionuclide tracers currently in development.

The use of more robust, affordable and efficient techniques and technologies in the application of medicine is presently a subject of huge interest and demand. The main purposes of Technology and Medical Sciences is to solidify knowledge in the fields of Technology and Medical Sciences and to define their key stakeholders. The book is of interest to academics in Engineering, Mathematics, Medicine, Biomechanics, Computation Sciences, Hardware Developers and Manufactures, Electronic and Instrumentation and Materials Science.

This issue reviews the latest advances and state of knowledge for the use of Diffusion Imaging (DI) in the clinical setting.? After covering the basic concepts for DI, topics appear such as DI in central nervous system, head and neck, chest, abdomen, pelvis, breast, and musculoskeletal system.? Lastly, a review of the use of DI for monitoring response to cancer treatment is included.

Incidentalomas, or tumors discovered unintentionally by radiologists, are a problem that all radiologists face in their practice. This issue provides not only an overview of neoplasms of the CNS, liver, chest, kidneys, pancreas, and adrenal glands commonly discovered during radiologic examinations but also provides a framework for understanding the legal implications and cost considerations involved for radiologists.

The field of medical imaging seen rapid development over the last two decades and has consequently revolutionized the way in which modern medicine is practiced. Diseases and their symptoms are constantly changing therefore continuous updating is necessary for the data to be relevant. Diseases fall into different categories, even a small difference in symptoms may result in categorising it in a different group altogether. Thus analysing data accurately is of critical importance. This book concentrates on diagnosing diseases like cancer or tumor from different modalities of images. This book is divided into the following domains: Importance of big data in medical imaging, pre-processing, image registration, feature extraction, classification and retrieval. It is further supplemented by the medical analyst for a continuous treatment process. The book provides an automated system that could retrieve images based on user's interest to a point of providing decision support. It will help medical analysts to take informed decisions before planning treatment and surgery. It will also be useful to researchers who are working in problems involved in medical imaging.

Articles in this issue include: "Basic Appearance of US Structures and Pitfalls?, "US of the Shoulder?, "US of the Elbow and Wrist?, "Prolotherapy and PRP Applications - Evidenced Based Discussion?, "US of the Hip & Lower Extremity?, "US Guided Injections in MSK Medicine?, "Physiatric Perspectives of MSK US?, "Orthopedic Perspectives of MSK US?, "Rheumatologic Perspectives of MSK US?, "Radiology Perspectives of MSK US?, "European Perspectives on MSK US?, "Sports Medicine Applications for MSK US?, ? "MSK US in Pain Medicine?, "US of Nerve Entrapments?, "US Guided BOTOX Therapy?, "Foot and Ankle.?

Ultrasonic imaging is an economic, reliable diagnostic technique. Owing to recent therapeutic applications, understanding the physical principles of medical ultrasonics is becoming increasingly important.

Covering the basics of elasticity, linear acoustics, wave propagation, nonlinear acoustics, transducer components, ultrasonic imaging modes, basics on cavitation and bubble physics, as well as the most common diagnostic and therapeutic applications, Fundamentals of Medical Ultrasonics explores the physical and engineering principles of acoustics and ultrasound as used for medical applications.

It offers students and professionals in medical physics and engineering a detailed overview of the technical aspects of medical ultrasonic imaging, whilst serving as a reference for clinical and research staff.

Ultrasound is a modality with broad applications in the imaging of the genitourinary tract. Reviewed are the uses of US imaging the kidneys, prostate, scrotum, and bladder. Also included are reviews of fetal genitourinary abnormalities, urinary tract infection, and tuberculosis. The issue is rounded out with articles on contrast agents and on US-guided interventions.

Dr. Kiesslich secured authors who are at the top of their field in GI Imaging to write articles that will serve as an up-to-date source for all gastroenterologists.? The issue is divided into sections devoted to imaging of the esophagus, stomach, small bowel, liver& pancreas, and colon; two articles are devoted to molecular imaging.? Readers will be very interested in the articles devoted to Contrast Enhanced and 3D-Endosonography, High Definition and Filter Aided Colonoscopy, and Autofluorescence and NBI Imaging in Barrett's Esophagus.

This publication presents topics on Head and Neck Ultrasound relevant to the Otolaryngologist. Topics include Head and ultrasound by the Otolaryngologist- why now?; Principles of Ultrasound; Head and Neck Anatomy and Ultrasound Correlation; Ultrasound Interpretation; Scanning Techniques for Head and Neck; Role of Ultrasound in Thyroid Disorders; Parathyroid localization with Ultrasound; Ultrasound-guided procedures for the office; Ultrasound in the pediatric population;? Ultrasound Applications in Trauma/military Settings; Emerging Technology in Head & Neck Ultrasound.

MRI Atlas of Human White Matter remains the only atlas to provide detailed anatomy of human brain white matter. Knowledge of this anatomy via diffusion tensor imaging (DTI )greatly enhances our understanding of brain function and neural connectivity. These advances promise to be particularly helpful with neurological diseases, such asAlzheimer's. The second edition offers an introduction to and description of the methodology, the 3D anatomy of individual tracts, and a series of color-coded orientation maps to delineate white matter anatomy in a slice-by-slice manner. Improvements over the 1st edition include: full segmentation of up to 176 regions of the brain, added definitions of gray matter to further understanding between white and gray matter structures, andthe addition of standardized stereotaxic coordinates. The atlasserves as avaluable resource for clinicians, researchers and graduate students in neuroscience, neurology, neurosurgery and radiology.
Visualization of brain white matter anatomy via 3D diffusion tensor imaging (DTI) contrasts and enhances relationship of anatomy to functionFull segmentation of 170+ brain regions more clearly defines structure boundaries than previous point-and-annotate anatomical labeling, andconnectivity is mapped in a way not provided by traditional atlasesElectronic files with viewing software can be made available via CD and/or BrainNavigator, allowing readers access to raw image files"