This issue of Hand Clinics, guest edited by Dr. Steve Haase, as well as the series' consulting editor Dr. Kevin Chung, will cover a number of key aspects of Dupuytren Disease. Topics discussed within the issue include, but are not limited to: Risk Factors, Disease Associations, and Dupuytren Diathesis, Pathologic Anatomy in Dupuytren Disease, Needle Aponeurotomy for Dupuytren Disease, Development of Collagenase Treatment for Dupuytren Disease, Collagenase Injection for Dupuytren Disease, Alternative and Adjunctive Treatments for Dupuytren Disease, Comparative Outcomes of Dupuytren Disease Treatment, Complications of Dupuytren Disease Treatment, The Role of Hand Therapy in Dupuytren Disease, Treatment of Recurrent Dupuytren Disease, and Advances in Minimally Invasive Treatment of Dupuytren Disease.

This comprehensive volume includes chapters on bone growth and development, bone tumor imaging, molecular genetics, and all classes of bone and joint tumors. This Fascicle is designed for residents, fellows, and practicing physicians in fields that treat and study patients with bone tumors, including pathology, orthopedics, radiology, medical oncology, and radiation oncology. Along with a wide range of superb illustrations, the authors' discussions integrate their experience, recent molecular data, and updated information from the World Health Organization Classification of Tumors of Soft Tissue and Bone.

Beautifully illustrated sections from various views, labeled clearly for easy reference. Illustrations by award-winning medical illustrator Vince Perez. This 2-page laminated guide includes: arm anterior view, head & trunk anterior view, clavicle superior view, leg & foot anterior view, hand palmar view, hyoid bone superior view, foot dorsal view, clavicle inferior, head & trunk posterior view, leg & foot posterior view, hand dorsal view, base of skull, and foot plantar view.

Surgery in Systemic Autoimmune Disease, Volume 15, describes the state-of-the-art of the use of surgery in treating the most common systemic autoimmune diseases (SADS). The volume consists of an introductory chapter concerning the impact of surgery on SADs, follow by eight chapters describing the use of surgery in the treatment of specific diseases in various areas (cardiology, gastroenterology, orthopedics, neurology. etc.) and the possible difficulties and complications. The final five chapters deal with the possible complications arising during the course of biological and non-biological treatment, also providing recommendation concerning their management. International in scope, the list of more than 20 contributors from Europa and America reads like a who's who of clinical researchers in the field.

This book provides a perspective on the current status of bioimaging technologies developed to assess the quality of musculoskeletal tissue with an emphasis on bone and cartilage. It offers evaluations of scaffold biomaterials developed for enhancing the repair of musculoskeletal tissues. These bioimaging techniques include micro-CT, nano-CT, pQCT/QCT, MRI, and ultrasound.

Genetics of Bone Biology and Skeletal Disease, Second Edition, is aimed at students of bone biology and genetics and includes general introductory chapters on bone biology and genetics. More specific disease orientated chapters comprehensively summarize the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder. The book is organized into five sections that each emphasize a particular theme, general background to bone biology, general background to genetics and epigenetics, disorders of bone and joint, parathyroid and related disorders, and vitamin D and renal disorders. The first section is specifically devoted to providing an overview of bone biology and structure, joint and cartilage biology, principles of endocrine regulation of bone, and the role of neuronal regulation and energy homeostasis. The second section reviews the principles and progress of medical genetics and epigenetics related to bone disease, including genome-wide association studies (GWAS), genomic profiling, copy number variation, prospects of gene therapy, pharmacogenomics, genetic testing and counseling, as well as the generation and utilizing of mouse models. The third section details advances in the genetics and molecular biology of bone and joint diseases, both monogenic and polygenic, as well as skeletal dysplasias, and rarer bone disorders. The fourth section highlights the central role of the parathyroids in calcium and skeletal homeostasis by reviewing the molecular genetics of: hyperparathyroidism, hypoparathyrodism, endocrine neoplasias, and disorders of the PTH and calcium-sensing receptors. The fifth section details molecular and cellular advances across associated renal disorders such as vitamin D and rickets.

Musculoskeletal Rehabilitation, Volume 2: Scientific Foundations and Principles of Practice provides a thorough review of the basic science information concerning the tissues of the musculoskeletal system impacted by injury or disease, as well as the guiding principles upon which rehabilitation interventions are based. This volume divides information into two sections: scientific foundations and principles of intervention, providing readers with a guiding set of clinical foundations and principles upon which they can easily develop treatment interventions for specific impairments and functional limitations. Clinical application case studies help readers apply what they learn in the classroom to real life situations. Evidence-based content uses over 5,000 references to support the basic science information principles for rehabilitation interventions and provide the best evidence and physiological reasoning for treatment. Over 180 tables and 275 text boxes highlight key points within the text for better understanding. Expert editors David Magee, PhD, PT, James Zachazewski, DPT, SCS, ATC, Sandy Quillen, PT, PhD, SCS, FACSM and over 70 contributors provide authoritative guidance on the foundations and principles of musculoskeletal rehabilitation practice.

This issue of Hand Clinics, guest edited by Dr. Joshua Adkinson, will cover several import aspects of the Management of Spastic Conditions of the Upper Extremity. At the invitation of consulting editor Dr. Kevin Chung, Dr. Adkinson put together a comprehensive issue, which covers: Etiologies; Assessment measures and motion analysis; Non-surgical treatment options; Surgical management of spasticity of the thumb and fingers, wrist and forearm, elbow, and shoulder; Management of spastic upper extremity joint contractures; Technical pearls of tendon transfers; Selective neurotomy; Neurosurgical management; Outcomes after surgical treatment; The future of upper extremity spasticity management; and Management of spinal cord injury-induced upper limb spasticity, among others.

Research into metabolic bone disease has made remarkable progress over the last 20 years, with the identification of numerous new molecules and pathways regulating bone cells as well as their plasma milieu. Their activities are largely regulated by the physiological status of the body incorporating the biochemical, physical and mechanical functions of bone, kidney and intestinal tissues. The Physiological Basis of Metabolic Bone Disease integrates the knowledge derived from molecular techniques with the fundamental principles of the physiology of these organs. The book places particular emphasis on bone cell activities and the regulation of plasma calcium, phosphate homeostasis, and whole body nutrition. It reviews the nutritional requirements for calcium and vitamin D for the prevention of osteoporosis. It covers vitamin D, calcium and phosphate absorption; calcium sensing receptors; the role of parathyroid hormone; physiological actions of calcitonin; and the diagnosis and significance of osteoporosis. Reviewing the physiological significance of advances in the molecular biology of metabolic bone disease, this book provides a valuable reference for researchers as well as practicing clinicians.

Bone Drugs in Pediatrics brings together in one place the evidence for the use of certain drugs in the treatment and prevention of bone loss in children, as well as the reservations still present in the pediatric community regarding their use. Beginning with a discussion of developmental pharmacokinetics and drug development for pediatric diseases where bone loss occurs, such as osteogenesis imperfecta, the physiology of pediatric bone and how best to monitor the safety and efficacy of these drugs is presented. The pros and cons of utilizing the drugs themselves - such as bisphosphonates, antiresorptives and anabolic agents - within the pediatric population are carefully considered, with an eye toward safe and effective integration. The potential use of drugs in future treatment is also highlighted. On the whole, Bone Drugs in Pediatrics is a cogent presentation of the ongoing debate surrounding the potential for pharmacological interventions in pediatric bone loss.

The Year Book of Hand and Upper Limb Surgery brings you abstracts of the articles that reported the year's breakthrough developments in hand surgery, carefully selected from a variety of journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. There's no faster or easier way to stay informed!

Over the last decade, the advent of biologic agents has greatly revolutionized therapeutic medicine in the management of chronic inflammatory diseases, such as rheumatoid arthritis, Crohna (TM)s disease, and psoriasis. Elucidation of the complex web of cytokine network and the roles of these cytokines in the pathogenesis of inflammatory disorders provided one of the key catalysts for the advancement of targeted biologic therapy in autoimmune and inflammatory diseases.

TNF-alpha is known to play a crucial role in the pathogenesis of many chronic inflammatory diseases. Elevated levels of TNF-alpha have been demonstrated in Crohna (TM)s disease, psoriasis, psoriatic arthritis, and rheumatoid arthritis, suggesting a role for TNF-alpha in their pathogenesis. Although TNF-alpha plays a critical role in the activation of innate and acquired immune responses, the persistence of the immune response and inappropriate production of TNF-alpha can produce pathological changes resulting from chronic inflammation and tissue damage.

This volume provides a comprehensive overview of the development, pharmacology, efficacy, and safety of the currently available TNF-alpha inhibitors a" etanercept, infliximab, and adalimumab. The most recent preclinical and clinical data is presented on this topic, which should be of interest to the preclinical researcher, the clinician, and the patient who wants to learn more about these therapies.

This one-of-a-kind book delivers challenging, clinically relevant case-based learning tools regarding orthopedics and sports medicine for advanced practice nursing students and practitioners. Written by nurse practitioner/educators, it fills a gap in information and guidelines for treatment of this population in primary and acute care environments. Cases across the lifespan cover areas of orthopedics and sports medicine most likely to be encountered. Cases are described in depth to foster a comprehensive learning experience and to facilitate inductive and deductive critical reasoning. Each follows a template that encompasses the context for the case, chief patient complaints and history along with physical assessment findings, diagnostic evaluation, interventions, evaluation of care and outcome, and references for additional information. An accompanying teaching guide aids instructors in accelerating critical thinking. Key Features: Fills an identified gap in available literature Reflects both primary care and acute care across the lifespan Includes referral red flags and scope of practice for each case Formats cases for both inductive and deductive reasoning Offers focused instructor manual to facilitate meaningful learning

Advances in Pathobiology and Management of Paget's Disease of Bone presents an essential collection of up-to-date knowledge about the pathophysiology, genetics, and treatment of Paget's disease. It covers the comprehensive information related to clinical perspectives, epidemiology, genetics, environmental factors such as viral etiology, molecular abnormalities, complications such as osteosarcoma, and current and future treatment for Paget's disease. This book serves as a useful volume for basic scientists, graduate students, and practicing clinicians in understanding the pathobiology, etiology, and treatment of this disease.

Bone circulation is important to our understanding of many major orthopedic conditions such as osteoarthritis, osteoporosis, repair, and tumors. Yet, circulatory physiology, basic to all healthy organs and most diseases, has been difficult to study in the skeleton. The biological regulation of blood flow is complex and the tissues have been relatively inaccessible to measurement. In recent years, however, advances have been made in understanding circulatory physiology and fluid flow in bone, functional measurement of blood flow, and the roles of circulation in bone turnover and repair. These advances have enhanced our insights into bone homeostasis and the interrelationships of circulation and skeletal biology, including repair and disease.This seminal volume presents updated information on circulatory physiology of bone and fluid flow through the bone matrix. It then describes new techniques in quantifying and imaging bone circulation. A clinical section covering circulatory elements of skeletal diseases provides valuable insight into pathophysiology that may serve as diagnostic biomarkers or therapeutic targets.

The 9 chapters in this book have been selected from the contents of the Musculoskeletal System section in Grainger & Allison's Diagnostic Radiology 6e. These chapters provide a succinct up-to-date overview of current imaging techniques and their clinical applications in daily practice and it is hoped that with this concise format the user will quickly grasp the fundamentals they need to know. Throughout these chapters, the relative merits of different imaging investigations are described, variations are discussed and recent imaging advances are detailed. Please note that imaging techniques of the spine are considered in the separate section "The Spine" in Grainger & Allison's Diagnostic Radiology 6e.

Chronic pain from job-related stressors is responsible for countless lost work hours and considerable lost revenue--and if current statistics are any indication, the problem isn't going away anytime soon. Between rising numbers of affected workers and rising health care costs, musculoskeletal pain has taken on crisis proportions.

The"Handbook of Musculoskeletal Pain and Disability Disorders in the Workplace" addresses the complex state of the issues in authoritative and practical fashion. Divided evenly between common occupational pain disorders, conceptual and methodological issues, and evidence-based intervention methods, this comprehensive reference presents current findings on prevalence, causation, and physical and psychological aspects common to these disorders. Attention is given to working-world concerns, including insurance and compensation issues and AMA guidelines for disability evaluations. Also, specialized chapters offer lenses for understanding and administering the best approaches for treating specific pain disorders, as well as explore what workplaces can do to accommodate affected employees and prevent injuries from occurring in the first place. Among the "Handbook"'s featured topics:

Chronic widespread pain.Whiplash injuries: etiology, assessment, and treatment.Acute, postacute, and chronic disorders: differences and potential recovery outcomes.Medicolegal issues involved in occupational musculoskeletal injuries.Self-management techniques for musculoskeletal pain. Models of return-to-work for musculoskeletal disorders.

The"Handbook of Musculoskeletal Pain and Disability Disorders in the Workplace" offers expert, up-to-date coverage suited to health psychologists, rehabilitation specialists (including physical, vocational, and occupational therapists), human resources and disability management professionals, and occupational medicine physicians.

"

Shoulder and Elbow Trauma and Its Complications: Volume 2: The Elbow provides an update on elbow surgery, a type of procedure that is seeing a significant increase in recent years. Although some of these surgeries are due to an aging population, a large proportion of operations are being performed on younger patients who have damaged their joints through physical activity. Worldwide, many of the injuries sustained through sport and physical activity are fractures which can be difficult to treat and can cause complications. Chapters in this detailed book will look at the most common types of elbow trauma and how to manage complications in surgery.

Complications of hand injuries are very common, and the primary goal of the treatment of hand trauma is simply that of avoiding complications. They can be considered to be complications of missed diagnoses, complications of treatment, or complications of injuries.

This book provides an integrative approach for the management and care of the arthritis patient. Many different psychological, social, and behavioral factors have been shown to affect the quality of life of arthritis patients beyond the effects of the disease and the response to medications and treatments. The book establishes a biopsychosocial framework for understanding the interplay between psychological and physical aspects of rheumatic disease and summarizes the research about the psychosocial aspects that affect patients with arthritis, including stress, social support, doctor-patient communication, and sleep patterns. It explores the practice of incorporating psychological and behavioral approaches in the rheumatology clinic in order to surmount the problems of access and enhance the quality of care, promotes a comprehensive perspective on the numerous issues affecting persons with arthritis, and provides clinical guidelines for management. Psychosocial Factors in Arthritis is a valuable resource for behavioral medicine researchers, behavioral clinicians, and a range of arthritis professionals, including rheumatologists, nurses, and other allied health service practitioners.

Clear, concise description of more than 100 US-guided injections in musculoskeletal medicine. A Doody's Core Title for 2022! Atlas of Ultrasound-Guided Musculoskeletal Injections includes numerous tips and tricks from the field's most experienced and respected practitioners. This unique and state-of-the-art text is ideal for physiatrists, rheumatologists, sports medicine physicians, radiologists, pain medicine specialists, and orthopedic surgeons. With a focus on safety and efficacy, this atlas is a worthwhile investment for any practitioner looking to add ultrasound-guided procedures to their practice or is looking to sharpen their skills. The book opens with informative coverage of the fundamentals of MSK US, including ultrasound physics, preparation and set-up for MSK US procedures, and the rationale and evidence for performing these procedures. The main body of the book dedicates one chapter to a specific US-guided injection or procedure. Each chapter design includes sections on key points, pertinent anatomy, common pathology, US imaging, indications, and technique. The book is divided into 8 sections: Shoulder Elbow Hand and wrist Pelvis Knee Foot and ankle Special procedures (rotator cuff, Percutaneous Trigger finger release, Ultrasound-guided Carpal Tunnel release, and Tenex) Introduction Atlas of Ultrasound-Guided Musculoskeletal Injections includes coverage of the full spectrum of procedures, ranging from basic US guided joint injections to perinerual injections, tenotomies, and surgical procedures such as percutaneous A1 pulley release, making the book the field's first true cornerstone text and the "go to" resource for any clinician interested in the subject.

Neuromuscular disorders are diagnosed across the lifespan and create many challenges especially with infants, children and adolescents. This new edition of the definitive reference, edited by the established world renowned authorities on the science, diagnosis and treatment of neuromuscular disorders in childhood is a timely and needed resource for all clinicians and researchers studying neuromuscular disorders, especially in childhood. The 2nd Edition is completely revised to remain current with advances in the field and to insure this remains the standard reference for clinical neurologists and clinical research neurologists. The 2nd Edition retains comprehensive coverage while shortening the total chapter count to be an even more manageable and effective reference.
Carefully revised new edition of the classic reference on neuromuscular disorders in infancy, childhood and adolescence.Definitive coverage of the basic science of neuromuscular disease and the latest diagnosis and treatment best practices.Includes coverage of clinical phenomenology, electrophysiology, histopathology, molecular genetics and protein chemistry

Congential myopathies, Muscular dystropies, Glycogen storage diseases of muscle, and Idiopathic and Inflammatory myopathies are presented in this volume of Neurologic Clinics. Topics include: Muscle channelopathies; Pompe disease; Congenital myopathies and muscular dystrophies; Duchenne and Becker muscular dystrophies; Distal myopathies; Limb-girdle muscular dystrophy; Fascioscapulomuneral muscular dystrophy; Myotonic dystrophy; Metabolic and mitochondrial myopathies; Sporadic inclusion body myositis; Toxic myopathies; Idiopathic Inflammatory myopathies; Approach to muscle disease.

Get immediate access to crucial information about the most common EMG studies.

This handy, practical resource designed for quick reference at the point of care covers a wide spectrum of electrodiagnostic tests. Written for both novice and experienced electromyographers, this at-a-glance guide is concise enough to fit in a pocket, yet replete with essential technical detail, pearls, and clinical photos to illustrate proper study set-ups.

"Pocket EMG" covers what you need to know to successfully perform nerve conduction and needle EMG studies in a fast-paced clinical environment. It also includes helpful protocols for specific clinical problems.

The first section is devoted to nerve conduction studies and covers sensory and motor studies of the upper and lower extremities, late responses, and other tests including facial motor nerves, blink reflex, and repetitive nerve stimulation. Section two covers needle electromyography and catalogs set-ups for upper and lower extremity tests, paraspinals, and facial muscles. The final two sections contain study protocols for presenting chief complaints or suspected diagnoses, normal values, and high-yield tables and lists. Each test includes a photograph of the proper set-up, indications for performing the test, technical pointers, and physiological considerations.

Key Features:

Organized consistently and pocket-sized for quick reference in the EMG lab Includes a photo of the proper set-up for each test, indications for performing the test, and clinical pearls and pointers to enhance skills Contains study protocols for common complaints, normal value ranges for individual tests, and high-yield tables and lists

In 1990, Dr. Kenneth Krackow wrote The Technique of Total Knee Arthroplasty to teach the basics of TKA for end-stage arthritis-everything from nonsurgical to surgical intervention and postoperative rehabilitation. Now completely revised for a new generation of surgeons, the 2nd Edition of this classic text continues its original goal of helping advanced practitioners acquire more knowledge and skill in primary and revision total knee arthroplasty. This fully updated volume, revised by Dr. Krackow and his former fellows Drs. William M. Mihalko and Michael A. Mont, keeps you current with major changes and advances in field, including patient optimization, outpatient procedures, robotics and new technology, difficult decisions during surgery, and more. Offers comprehensive and expert coverage of both inpatient and outpatient primary TKA, now fully revised with new chapters on Patient Considerations, Modifications, Optimizing the Important Comorbidities, TKA Balancing, and more. Addresses key issues of patient optimization such as obesity, diabetes, heart disease, rheumatoid arthritis, and peripheral vascular disease. Provides evidence for TKA outcomes and complications: "What do I tell my patient?" Focuses on the latest and best techniques and surgical approaches, including computer and robotic assisted surgery, uncemented TKA, assessing and planning for the difficult TKA, outpatient TKA considerations, and preventing readmissions post-surgery. Discusses how to handle all deformity aspects of the lower extremity, bone defects, and ligamentous insufficiency during surgery. Includes numerous illustrations, line art, radiographs, and clinical photos for optimal visualization of each procedure. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.