This issue of Foot and Ankle Clinics, guest edited by Dr. Normal Espinosa, will cover a number of important aspects of the Subtalar Joint in relation to foot and ankle surgery. Topics discussed in this issue include, but are not limited to: Anatomy of the subtalar joint; Biomechanics of the subtalar joint (including normal and pathologic); Open technique for in-situ subtalar fusion; Traumatic injury to the subtalar joint; subtalar instability; and Fractures of the lateral process of talus, among others.

This issue of Foot and Ankle Clinics will be Guest Edited by Dr. Woo-Chun Lee and focus on a three dimensional approach to Hallux Valgus Deformity and Treatment. Some of the articles in this issue will include: Why there are so many different surgeries for hallux valgus; Imaging of hallux valgus. How to approach the deformity; Sesamoid position in hallux valgus in relation to the coronal rotation of the first metatarsal; Comparison of 3D displacement among different metatarsal osteotomies; Proximal supination osteotomy of the first metatarsal for hallux valgus; First metatarsocuneiform joint mobility: radiographic, anatomic, and clinical characteristics of the articular surface; Lapidoplasty; How to use a 3 dimensional approach to correct HV with a distal metatarsal osteotomy; and Medial column instability/ HV and how it relates to PTTD, among others.

This issue of Orthopedics Clinics will be surveying a broad range of topics across sub-specialty areas on Evidence-based Medicine in Orthopedics. Each issue in the series is edited by an experienced team of surgeons from the Campbell Clinic. Articles will discuss the following topics, among others: Use of Tourniquets in Limb Trauma Surgery; Cerebral Palsy; Injection therapies for rotator cuff disease; Antibiotic prophylaxis in shoulder and elbow surgery; venous thromboembolism prophylaxis in shoulder surgery; Patient Reported Outcomes in Foot and Ankle Surgery; and VTED prophylaxis in foot and ankle surgery.

This issue of Foot and Ankle Clinics, edited by Dr. Todd Irwin, will cover Management of Metatarsalgia and Painful Lesser Toe Deformities. Topics covered in this volume include, but are not limited to: Conservative Treatment of Metatarsalgia and Lesser Toe Deformities; Treatment of Metatarsalgia with Distal Osteotomies; Treatment of Metatarsalgia with Proximal Osteotomies; Complications of Metatarsal Osteotomies; Gastrocnemius Recession for Metatarsalgia, Hammertoes and Clawtoes; Treatment of Rigid Hammertoe Deformity; Lesser Metatarsophalangeal Joint Instability; Managing Complications of Lesser Toe and Metatarsophalangeal Joint Surgery; and Treatment of Freiberg's Disease.

This issue of Hand Clinics, guest edited by Dr. Asif M. Ilyas, will cover Complex Trauma Management of the Upper Extremity. Topics discussed in the volume include: Open Hand Fractures; Open Fractures of the Upper Extremity, including Antibiotics and Debridement Strategies; Evaluation and Emergency Management for the Mangled Hand; Acute Carpal Tunnel Syndrome and Distal Radius Fractures; Open Distal Radius Fractures; Forearm Compartment Syndrome; Traumatic Wounds of the Upper Extremity; Evaluation and Treatment Strategies; Ulnar Nerve Management with Distal Humerus Fractures; and Radial Nerve Palsy Management after Humerus fractures, among others.

1 Die Press-Fit-Verankerung.- 2 Indikation, Technik und Ergebnisse der konischen Schraubpfanne bei Primar-und Revisionseingriffen.- 3 Keramik-Polyethylen versus Metall-Polyethylen - Eine in vivo-Analyse.- 4 Keramische Pfanneneinsatze fur totalen Huftgelenkersatz.- 5 Mittelfristige Ergebnisse mit der Keramik-Gleitpaarung in der Huftendoprothetik.- 6 Werkstoffkundliche Aspekte zum UHMW-Polyethylen.- 7 Muller-Bogenschaft-Prothese - Langzeitergebnisse mit vollstandiger Datenerfassung..- 8 Verankerungsprinzipien des Exeter-Schaftes.- 9 Der Lubinus-Schaft.- 10 CLS-Multicenterstudie - 11jahrige Erfahrungen.- 11 Konische Schaftverankerung bei zementfreien Huftendoprothesen.- 12 Die CHENDO-Femurprothese - Trabekular orientiertes Endoprothesensystem.- 13 Bionik als Grundlage eines trabekular orientierten Endoprothesensystems.- 14 CL. ESKA-Stiele/Endoprothesen.- 15 Die Druckscheibenprothese - Fruhergebnisse bei Patienten mit Arthritis.- 16 Zementfreie Schaftverankerung der Individualprothese..- 17 Axis-Stufenschaft.- 18 Die ESKA-Schenkelendoprothese Cut zur inneren metaphysaren Fixation.- 19 Resultate nach zementfreier Implantation des BiContact-Huftendoprothesengeradschaftes.- 20 Robotik am Huftgelenk - Das Robotersystem Robodoc.- 21 Computerassistierter Einbau von Huftprothesenschaften mit dem CASPAR-System.- 22 Erste Erfahrungen mit dem Surgigate-System von Medivision bei der Implantation der Huftpfanne.- 23 Erste Erfahrungen aus der klinischen Testung der computerassistierten Pfannenpositionierung bei der Implantation von Huft-Total-Endoprothesen mit dem NavitrackTM-System.- 24 Computergestutzte Prothesenauswahl und Implantationskontrolle.

This issue of Foot and Ankle Clinics, guest edited by Dr. Kent Ellington, focuses on The Flatfoot and will include articles on the following topic areas: Recurrent deformity due to Deltoid/Spring Failure; Severe stage 2 - fuse or reconstruct?; Undercorrected reconstruction; Overcorrected reconstruction; What to do with the spring ligament; Calcaneal osteotomies: Pearls and Pitfalls; Evans osteotomy complications; NC sag in the flatfoot, and more!

The content of this book is intended to provide the toxicologist in drug development in the pharmaceutical and biotechnology industries with a broad understanding of bone and its interactions with other organ systems in safety assessments. The book is divided into three parts. The first part describes our current understanding of bone biology and its primary regulatory pathways. Additional chapters address regulatory and study design considerations for incorporating bone end points in toxicology studies, with special consideration being given to juvenile toxicology studies. This is intended to address recent regulatory requirements to evaluate skeletal development for drugs in development for pediatric populations. The second part of the book describes the principal techniques and methods used in bone research; understanding how these end-points are derived is fundamental to their appropriate application. These first two parts of the book provide the background and the means to develop the concepts in part three which describes bone and its interaction with other organ systems. The unique series of chapters in part three, contributed to by key leaders in their respective fields and in bone research, provides a comprehensive collective work. Although constantly evolving, the crosstalk and interaction of the skeleton with several organ systems is now recognized and well documented, such as for the reproductive system, muscle and kidney, while our understanding of the interaction with other organ systems, such as the immune system and CNS, is in its infancy. Recent work highlights the key role of the skeleton in the regulation of energy metabolism and the impact this has on research in metabolic diseases such as obesity and diabetes. The hope is that this book will enlighten many and encourage more to explore the impact of new compounds on the skeleton in the development of effective and safe drugs.

This issue of Hand Clinics will include the following articles: Management of Acute Adult Hand Burns; Management of Acute Pediatric Hand Burns; Electrical Injury; Frostbite Injury; The Biologic Principles of Scar and Contracture; Postburn Contractures of the Hand; Biology and Treatment of Upper Extremity Heterotopic Ossificatio; Postburn Contractures of the Elbow and Heterotopic Ossification; Reconstruction of the Adult and Pediatric Burned Hand; Microsurgical Reconstruction of the Burned Hand; The Use of Dermal Skin Substitutes for the Treatment of the Burned Hand; and many more exciting articles!

This issue of Orthopedic Clinics focuses on Orthobiologics. Article topics include: Does Prior Cartilage Restoration Impact Outcomes Following Knee Arthroplasty?; Clinical Applications of Tissue Engineering in Joint Arthroplasty: Current Concepts Update; Usage of Bone Graft Substitutes; Bone morphogenetic protein; Role of Bone Marrow Aspirate in Orthopaedic Trauma; Orthobiologics in Pediatric Sports Medicine, and more!

This issue of Clinics in Podiatric Medicine and Surgery will include articles that focus on achilles tendon pathology and will include: Anatomy and Blood supply; Imaging Indications and Techniques; Mid-substance Tendinopathy Background & Clinical Evaluation; Mid-substance Tendinopathy; Non-Surgical Management; Mid-substance Tendinopathy; Percutaneus Techniques; Mid-substance Tendinopathy; Surgical Management; and a plethora of additional articles on this exciting topic.

Vascular Pharmacology: Smooth Muscle provides up-to-date information on the structure, function, signaling, and development of vascular smooth muscle. Contributors include prominent scientists and highly-recognized experts with major accomplishments in the field of vascular smooth muscle research.

This issue will focus on both adult and pediatric spine trauma. Featured articles are as follows: Pharmacologic Treatment of SCI; Classification of Adult Subaxial Cervical Trauma; Classification and Management of Pediatric Craniocervical Injuries; Classification and Management of Pediatric Subaxial Injuries; Classification of Adult Thoracolumbar Injuries; Management of Pediatric Thoracolumber Injuries; Treatment of Odontoid Fractures in the Aging Population; Treatment of Facet Fractures in the Cervical Spine; and many more!

This issue of Radiologic Clinics of North America focuses on Skull Base Imaging, and is edited by Dr. Nafi Aygun. Articles will include: Overview of Expanded Endonasal Approaches to the Skull Base for Radiologists; Imaging of Paranasal Sinuses and Anterior Skull Base; Imaging of the Sella Turcica and Pituitary Gland; Imaging of Diplopia; Imaging of the Central Skull Base; Imaging of Vascular Compression Syndromes (Including Trigeminal Neuralgia and Hemifacial Spasm); Imaging of the Posterior Skull Base (Lower Cranial Nerves Excluding the 7th and 8th Nerves); Imaging Evaluation and Treatment of Vascular Lesions at the Skull Base; Perineural Spread of Tumor in the Skull Base; Advanced Imaging Techniques of the Skull Base; High Resolution Imaging of the Skull Base; Imaging of Cerebrospinal Fluid Rhinorrhea and Otorrhea, and more!

This issue of Endocrinology and Metabolism Clinics, guest edited by Dr. Albert Shieh of UCLA, is devoted to Bone Disorders. Articles in this outstanding issue include: Role of Osteocyte in Bone and Non-Bone Disease; Bone-Fat Interaction; Imaging Beyond DXA; Vitamin D in African-Americans; Pre-Menopausal Osteoporosis; Combined Pharmacologic Therapy in Osteoporosis; Drug-Related Adverse Events in Osteoporosis; Novel Therapies for Osteoporosis; Diabetes and Bone Disease; Bariatric Surgery and Bone Metabolism; Hyperparathyroidism and Bone Microarchitecture; FGF-23 Mediated Bone Disease; and Endothelin-Related Bone Disorder.

This issue will include: Percuataneous Surgery for mild to moderate hallux valgus, percuataneous surgery for severe hallux valgus, technique and outcomes of chevron and basal osteotomies, percutaneous metatarsalgia and lesser toe surgery, distal minimally invasive metatarsal ostetomies and lesser toe correction, and many more exciting articles.

The decision process for determining when to return an injured or ill athlete to practice or competition includes many factors. This issue will cover Return to Play Following Cervical Disc Surgery; Return to Play Following Anterior Shoulder Dislocation and Stabilization Surgery; Return to Play Following Shoulder Surgery in Throwers; Return to Play Following Ulnar Collateral Ligament Reconstruction; Return to Play Following Hand and Wrist Fractures; and many more articles on returning to play post musculoskeletal injuries.

Mutilated hand injuries are one of the most challenging reconstruction problems than can confront hand surgeons. This issue will cover outcome and functional measurement in mutilating hand injuries; skin coverage considerations in a mutilating hand injury; reconstruction of major degloving injuries of the hand; challenges posed by delayed presentation of mutilating hand injuries; and many more articles surrounding this topic.

This issue of MRI Clinics of North America focuses on MR Imaging of the Spine, and is edited by Dr. Mario Muto. Articles will include: Diagnostic Approach to Pediatric Spin Pathology; Neuroimaging of Scoliosis and Sagittal Balance; Neuroimaging of the Degenerative Spine; Neuroimaging of Spinal Instability; Neuroimaging of the Traumatic Spine; Neuroimaging of Spine Infections; Neuroimaging of the Post Operative Spine; Neuroimaging of Spinal Canal Stenosis; Neuroimaging of Spinal Tumors, and more!

Duchenne Muscular Dystrophy, an inherited and progressive muscle wasting disease, is one of the most common single gene disorders found in the developed world. In this fourth edition of the classic monograph on the topic, Alan Emery and Francesco Muntoni are joined by Rosaline Quinlivan, Consultant in Neuromuscular Disorders, to provide a thorough update on all aspects of the disorder. Recent understanding of the nature of the genetic defect responsible for Duchenne Muscular Dystrophy and isolation of the protein dystrophin has led to the development of new theories for the disease's pathogenesis. This new edition incorporates these advances from the field of molecular biology, and describes the resultant opportunities for screening, prenatal diagnosis, genetic counselling and from recent pioneering work with anti-sense oligonucleotides, the possibility of effective RNA therapy. Although there is still no cure for the disorder, there have been significant developments concerning the gene basis, publication of standards of care guidelines, and improvements in management leading to significantly longer survival, particularly with cardio-pulmonary care. The authors also investigate other forms of pharmacological, cellular and gene therapies. Duchenne Muscular Dystrophy will be essential reading not only for scientists and clinicians, but will also appeal to therapists and other professionals involved in the care of patients with muscular dystrophy.

This issue of Orthopedic Clinics will focus on orthopedic urgencies and emergencies. Articles to be included will cover pediatrics, trauma, upper extremity, adult reconstruction, and foot and ankle.

This issue will include articles on Nerve Repair and Nerve Grafting, Nerve Regeneration, Nerve Transfers to Restore Shoulder Function, Nerve Transfers to Restore Elbow Function, and many more!

This book describes in detail current best practice in the diagnosis and treatment of malignant pediatric bone tumors and also discusses other important aspects of management. Clinical assessment, the role of different imaging modalities and choice of biopsy procedure are explained and an individual chapter is devoted to diagnostic pathology. The treatment-oriented chapters offer in-depth descriptions of chemotherapeutic regimens, radiation therapy, limb-salvage options and amputation-related issues and in addition consider the approach to lung nodules, the role of biomarkers, off-therapy monitoring and the treatment of relapse. Psychosocial impacts and needs are addressed and guidance provided on nursing during treatment and rehabilitation following orthopaedic surgery. Closing chapters evaluate emerging therapies and discuss disparate aspects of survivorship. The authors are acknowledged experts and include many contributors from the Nationwide Children's Hospital, a leading pediatric care facility in the United States.

This book contains the full papers presented at the MICCAI 2014 workshop on Computational Methods and Clinical Applications for Spine Imaging. The workshop brought together scientists and clinicians in the field of computational spine imaging. The chapters included in this book present and discuss the new advances and challenges in these fields, using several methods and techniques in order to address more efficiently different and timely applications involving signal and image acquisition, image processing and analysis, image segmentation, image registration and fusion, computer simulation, image based modeling, simulation and surgical planning, image guided robot assisted surgical and image based diagnosis. The book also includes papers and reports from the first challenge on vertebra segmentation held at the workshop.