This issue of MRI Clinics of North America focuses on Functional MRI in Oncology. Articles will include: Functional MRI techniques in oncology in the era of personalized medicine, MRI biomarkers and surrogate endpoints in oncology clinical trials, Therapy monitoring with functional MRI, Multiparametric MRI in the assessment of brain tumors, Multiparametric MRI of breast cancer, Functional MRI in chest malignancies, Multiparametric MRI in abdominal malignancies, Assessment of musculoskeletal malignancies with functional MRI, Evaluation of head and neck tumors with functional MRI, Role of multiparametric MRI in malignancies of the urogenital tract, Diffusion-weighted imaging in oncology, Functional MRI in gynecologic cancer, Assessment of angiogenesis with MRI: DCE-MRI and beyond, Imaging of tumor metabolism: MR spectroscopy, and more!

MRI of the Elbow and Wrist is explored in this important issue in MRI Clinics of North America. Articles include: Approach to MRI of the Elbow and Wrist: Technical Aspects and Innovation; MRI of the Elbow; Extrinsic and Intrinsic Ligaments of the Wrist; MRI of the Triangular Fibrocartilage Complex; Carpal Fractures; MRI of Tumors of the Upper Extremity; MRI of the Nerves of the Upper Extremity: Elbow to Wrist; MR Arthrography of the Wrist and Elbow; MRI of the Wrist and Elbow: What the Hand Surgeon Needs to Know; Imaging the Proximal and Distal Radioulnar Joints; MR Angiography of the Upper Extremity, and more!

Editor Hersh Chandarana, MD and authors review Advanced MR Imaging in Clinical Practice. Articles will include: Current Status of Diffusion Weighted Imaging; Current Status of Perfusion Weighted Imaging; Non-gadolinium Enhanced MR Angiography; Pearls and Pitfalls of 3 T imaging; Implementing MR Neurography in Clinical Practice; Imaging around Hardware and Metal; Recent Advances in T1- and T2-Weighted Imaging of the Abdomen and Pelvis; Recent Advances in Neuro and Spine Imaging; Advances in MR Hardware and Software, and more!

Cardiac MR is explored in this important issue in MRI Clinics of North America. Articles will include: MR physics in practice; Ventricular mechanics: Techniques and applications; MR safety issues particular to women; Novel MR applications for evaluation of pericardial diseases; 4D flow applications for aortic diseases; T1 mapping: technique and applications; ARVD: An updated imaging approach; Imaging the metabolic syndrome; Coronary MRA: how to optimize image quality; Prognostic role of MRI in nonischemic myocardial disease; MRI for valvular imaging; MRI for adult congenital heart disease assessment; Cardiac MRI applications for cancer patients; Applications of PET-MRI for cardiovascular disease; Rings and slings, and more.

The application of nuclear magnetic resonance (NMR) metabolomics in cancer research requires an understanding of the many possibilities that NMR metabolomics can offer, as well as of the specific characteristics of the cancer metabolic phenotype and the open questions in cancer research. NMR metabolomics in cancer research presents a detailed account of the NMR spectroscopy methods applied to metabolomics mixture analysis along with a discussion of their advantages and disadvantages. Following an overview of the potential use of NMR metabolomics in cancer research, the book begins with an examination of the cancer metabolic phenotype and experimental methodology, before moving on to cover data pre-processing and data analysis. Chapters in the latter part of the book look at dynamic metabolic profiling, biomarker discovery, and the application of NMR metabolomics for different types of cancer, before a concluding chapter discusses future perspectives in the field.
Focused description of NMR spectroscopy needed by cancer biologists who are starting to use metabolomicsCurrent overview of knowledge related to the cancer metabolic phenotype from the perspective of metabolomics applicationsInformation about the best practices in NMR metabolomics experimentation and data preprocessing as applied to different sample types

Normal Variants and Pitfalls in Musculoskeletal MRI is explored in this important issue of MRI Clinics of North America. Articles will include: Shoulder MR Imaging Normal Variants and Imaging Artifacts; Elbow Magnetic Resonance Imaging Variants and Pitfalls; Pitfalls of Wrist MR Imaging; MR Imaging of the Hip: Normal Anatomic Variants and Imaging Pitfalls; Magnetic Resonance Imaging Pitfalls and Normal Variations: The Knee; Normal Variants and Pitfalls in MR Imaging of the Ankle and Foot; Magnetic Resonance Imaging of the Midfoot and Forefoot: Normal Variants and Pitfalls; MR Imaging Features of Common Variant Spinal Anatomy; Bone Marrow, and more!

The concept of Diffusion Tensor Imaging (DTI) is often difficult to grasp, even for Magnetic Resonance physicists. Introduction to Diffusion Tensor Imaging uses extensive illustrations (not equations) to help readers to understand how DTI works. Emphasis is placed on the interpretation of DTI images, the design of DTI experiments, and the forms of application studies. The theory of DTI is constantly evolving and so there is a need for a textbook that explains how the technique works in a way that is easy to understand - Introduction to Diffusion Tensor Imaging fills this gap.
* Uses extensive illustrations to explain the concept of Diffusion Tensor Imaging
* Easy to understand, even without a background in physics
* Includes sections on image interpretation, experimental design and applications

This indispensable guide gives concise yet comprehensive descriptions of the pulse sequences commonly used on modern MRI scanners. The book consists of a total of 65 self-contained sections, each focused on a single subject. Written primarily for scientists, engineers, radiologists, and graduate students who are interested in an in-depth understanding of various MRI pulse sequences, it serves readers with a diverse set of backgrounds by providing both non-mathematical and mathematical descriptions.
The book is divided into five parts. Part I of the book describes two mathematical tools, Fourier transforms and the rotating reference frame, that are useful for understanding MRI pulse sequences. The second part is devoted to a wide variety of radiofrequency (RF) pulses, and the third part focuses on gradient waveforms. Data acquisition, image reconstruction, and physiological monitoring related to pulse sequence design form the subject of Part IV of the book. Once this foundation is established, Part V of the book describes the underlying principles, implementation, and selected applications of many pulse sequences commonly in use today.
The extensive topic coverage and cross-referencing makes this book ideal for beginners learning the building blocks of MRI pulse sequence design, as well as for experienced professionals who are seeking deeper knowledge of a particular technique.
-Explains pulse sequences, their components, and the associated image reconstruction methods commonly used in MRI
-Provides self-contained sections for individual techniques
-Can be used as a quick reference guide or as a resource for deeper study
-Includes both non-mathematical andmathematical descriptions
-Contains numerous figures, tables, references, and worked example problems

This third volume of NMR Spectroscopy in the Undergraduate Curriculum continues the work we started with the first and second volumes in providing effective approaches for using nuclear magnetic resonance spectrometers as powerful tools for investigating a wide variety of phenomena at the undergraduate level. This volume focuses on upper-level courses and NMR spectroscopy across the curriculum. The applications and strategies in this volume will be helpful to those who are looking to transform their curriculum by integrating more NMR spectroscopy, to those who might not have considered NMR spectroscopy as a tool for solving certain types of problems, or for those seeking funding for a new or replacement NMR spectrometer.

Magnetic Resonance Image Reconstruction: Theory, Methods and Applications presents the fundamental concepts of MR image reconstruction, including its formulation as an inverse problem, as well as the most common models and optimization methods for reconstructing MR images. The book discusses approaches for specific applications such as non-Cartesian imaging, under sampled reconstruction, motion correction, dynamic imaging and quantitative MRI. This unique resource is suitable for physicists, engineers, technologists and clinicians with an interest in medical image reconstruction and MRI.

Breast MRI: State of the Art and Future Directions provides a comprehensive overview of the current applications of breast MRI, including abbreviated MRI, as well as presenting technical recommendations, practical implementation and associated challenges in clinical routine. In addition, the book introduces novel MRI techniques, multimodality imaging, and advanced image processing coupled with AI, reviewing their potential for impeding and future clinical implementation. This book is a complete reference on state-of-the-art breast MRI methods suitable for MRI researchers, radiographers and clinicians. Breast cancer is one of the leading causes of death among women with early detection being the key to improved prognosis and survival. Magnetic resonance imaging (MRI) of the breast is undisputedly the most sensitive imaging method to detect cancer, with a higher detection rate than mammography, digital breast tomosynthesis, and ultrasound.

Motion Correction in MR: Correction of Position, Motion, and Dynamic Changes, Volume Eight provides a comprehensive survey of the state-of-the-art in motion detection and correction in magnetic resonance imaging and magnetic resonance spectroscopy. The book describes the problem of correctly and consistently identifying and positioning the organ of interest and tracking it throughout the scan. The basic principles of how image artefacts arise because of position changes during scanning are described, along with retrospective and prospective techniques for eliminating these artefacts, including classical approaches and methods using machine learning. Internal navigator-based approaches as well as external systems for estimating motion are also presented, along with practical applications in each organ system and each MR modality covered. This book provides a technical basis for physicists and engineers to develop motion correction methods, giving guidance to technologists and radiologists for incorporating these methods in patient examinations.

Magnetic Resonance Imaging: Recording, Reconstruction and Assessment gives a detailed overview of magnetic resonance imaging (MRI), along with its applications and challenges. The book explores the abnormalities in internal human organs using MRI techniques while also featuring case studies that illustrate measures used. In addition, it explores precautionary measures used during MRI based imaging, the selection of appropriate contrast agents, and the selection of the appropriate modality during the image registration. Sections introduce medical imaging, the use of MRI in brain, cardiac, lung and kidney detection, and also discuss both 2D and 3D imaging techniques and various MRI modalities. This volume will be of interest to researchers, engineers and medical professionals involved in the development and use of MRI systems.

Quantitative Magnetic Resonance Imaging is a 'go-to' reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: The basic physics behind tissue property mapping How to implement basic pulse sequences for the quantitative measurement of tissue properties The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* The pros and cons for different approaches to mapping perfusion The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor maps and more complex representations of diffusion How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance Fingerprinting can be used to accelerate or improve tissue property mapping schemes How tissue property mapping is used clinically in different organs

Magnetic Resonance Imaging of The Pelvis: A Practical Approach presents comprehensive information to deal with commonly encountered pelvic pathologies. The content is developed by disease-focused experts aiming to share their experience to make the information easily applicable to clinical setting and research. The book covers a wide range of pelvic pathologies, and each chapter focuses on problem-solving approaches and includes tips and advice for multiple real-world scenarios. It also provides comprehensive-yet-tailored protocols, clear guidelines for indications, a detailed discussion of pathologies, descriptions of important differential diagnoses, and pitfalls and their solutions. It is a valuable resource for radiologists, researchers, clinicians, and members of medical and biomedical fields who need to understand better how to use MRI to base their diagnosis or advance their research work.

In this issue of PET Clinics, guest editors Drs. Harshad R. Kulkarni and Abass Alavi bring their considerable expertise to the topic of Prostate Cancer. PET imaging for prostate cancer continues to evolve as new radiotracers and imaging modalities are combined. This issue offers an up-to-date review of the most popular radiotracers and how PET imaging is combined with MR, CT, and ultrasound to provide the most accurate diagnosis of prostate cancer. Contains 12 practice-oriented topics including the role of ultrasound, CT, and MRI in managing patients with prostate cancer; Ga68 PSMA imaging; PET imaging for prostate cancer using F-18 Fluciclovine; PET imaging for prostate cancer using Ga-68 RM2; the role of NaF PET in the imaging of prostate cancer; and more. Provides in-depth clinical reviews on prostate cancer, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Hyperpolarized and Inert Gas MRI: Theory and Applications in Research and Medicine is the first comprehensive volume published on HP gas MRI. Since the 1990's, when HP gas MRI was invented by Dr. Albert and his colleagues, the HP gas MRI field has grown dramatically. The technique has proven to be a useful tool for diagnosis, disease staging, and therapy evaluation for obstructive lung diseases, including asthma, chronic obstructive pulmonary disease (COPD), and cystic fibrosis. HP gas MRI has also been developed for functional imaging of the brain and is presently being developed for molecular imaging, including molecules associated with lung cancer, breast cancer, and Alzheimer's disease. Taking into account the ongoing growth of this field and the potential for future clinical applications, the book pulls together the most relevant and cutting-edge research available in HP gas MRI into one resource.

Spin Resonance Spectroscopy: Principles and Applications presents the principles, recent advancements and applications of nuclear magnetic resonance (NMR) and electron paramagnetic resonance (EPR) in a single multi-disciplinary reference. Spin resonance spectroscopic techniques through NMR and EPR are widely used by chemists, physicists, biologists and medicinal chemists. This book addresses the need for new spin resonance spectroscopy content while also presenting the principles, recent advancements and applications of NMR and EPR simultaneously. Ideal for researchers and students alike, the book provides a single source of NMR and EPR applications using a dynamic, holistic and multi-disciplinary approach.

This issue of MRI Clinics of North America focuses on Breast Cancer, and is edited by Dr. Jessica Leung. Articles will include: Breast MRI: Atlas of anatomy, physiology, pathophysiology, and BI-RADS lexicon; Neoadjuvant therapy monitoring, including inflammatory breast cancer; Breast MRI biopsy considerations: Technique, histologic upgrading, and radiologic-pathologic concordance; Breast MRI techniques and developments: 1.5 vs 3T, diffusion, fast MRI, PET-MRI, and other developing techniques; ACR Accreditation, Performance Metrics, Reimbursement, and Economic Considerations in Breast MRI; Screening: high-risk and dense breasts, especially compared with tomosynthesis and ultrasound; Extent of breast disease, especially compared with tomosynthesis and ultrasound, with special focus on nodal assessment; Problem-solving tool for imaging finding and clinical symptoms of breast cancer; MRI compared with contrast-enhanced mammography; MRI compared with molecular breast imaging; MRI compared with positron emission mammography; How does MRI help care for my breast cancer patient? Perspective of a surgical oncologist; How does MRI help care for my breast cancer patient? Perspective of a medical oncologist; How does MRI help care for my breast cancer patient? Perspective of a radiation oncologist; and more!

This issue of Neuroimaging Clinics of North America focuses on Functional Connectivity, and is edited by Dr. Jay Pillai. Articles will include: Applications of rs-fMRI to presurgical mapping: sensorimotor mapping; Dynamic functional connectivity methods; Machine learning applications to rs-fMRI analysis; Frequency domain analysis of rs-fMRI; Applications of rs-fMRI to epilepsy; Data-driven analysis methods for rs-fMRI; Applications of rs-fMRI to presurgical mapping: language mapping; Limitations of rs-fMRI in the setting of focal brain lesions; Applications of rs-fMRI to neuropsychiatric disease; Applications of rs-fMRI to Traumatic Brain Injury; Applications of rs-fMRI to neurodegenerative disease; Graph theoretic analysis of rs-fMRI; and more!

This issue of MRI Clinics of North America focuses on MR in the Emergency Room. Articles will include: MR Imaging of Stroke; MR Imaging of Acute Head and Neck Infections; Use of MR in the Evaluation of Cranial Trauma; MR of Spinal Emergencies; Emergency MR Imaging of Musculoskeletal Trauma; Use of MR in Non-traumatic Musculoskeletal Emergencies; MR Imaging of Abdominal Pain in Pregnancy; MR of Pelvic and Gastrointestinal Emergencies; Use of MR in Pediatric Emergencies; Use of MR in Pancreatico-Biliary Emergencies; and more!

Guest editors Claire Tempany and Tina Kapur review MR-Guided Interventions in this important issue in MRI Clinics of North America. Articles include: MR sequences and rapid acquisition for MR-guided interventions; MR-guided breast interventions: role in biopsy targeting and lumpectomies; MR-guided passive catheter tracking for endovascular therapy; MRgFUS update on clinical applications; MR-guided spine Interventions; MR-guided prostate biopsy; Interventional MRI Clinic: the Emory experience; MR-guided cardiac interventions; MR-guided functional neurosurgery; MR-guided active catheter tracking; MR-guided drug delivery; MR-guided thermal therapy for localized and recurrent prostate cancer; MR neurography for guiding nerve blocks and its role in pain management; MR-guided gynecologic brachytherapy; and more!

Chest MRI is explored in this important issue in MRI Clinics of North America. Articles include: MRI of Mediastinal Masses; State of the art: MR Imaging of the Thymus; Novel MR Applications for Pleural Evaluation; MRI Imaging of Chest Wall Tumors; MR Imaging of the Lungs with Hyperpolarized Gases: Technique and Applications; Lung Cancer Assessment with MR Imaging: An Update; PET/MRI in Chest Diseases; Imaging Pulmonary Arterial Thromboembolism: Challenges and Opportunities; MR Imaging of the Thoracic Aorta; MR Imaging of Thoracic Veins; State of the Art MR Imaging in Vascular Thoracic Outlet Syndrome; Pediatric Chest MR Applications, and more!

This issue, edited by Dr. Kirkland Davis, will comprehensively review imaging of the knee. Articles will include: Magnetic Resonance Imaging of the Meniscus; MRI of Cruciate Ligaments; Magnetic Resonance Imaging of the Extensor Mechanism; Quantitative Magnetic Resonance Imaging of the Articular Cartilage of the Knee Joint; Magnetic Resonance Imaging of the Pediatric Knee; MRI of Extra-Synovial Inflammation and Impingement about the Knee; A Biomechanical Approach to Interpreting MRI of Knee Injuries; MRI Assessment of Arthritis of the Knee; MRI of the Post-Operative Meniscus; MR Imaging of Cartilage Repair Procedures; Imaging the Knee in the Setting of Metal Hardware, and more!