Functional Magnetic Resonance Imaging provides a comprehensive introduction to fMRI. The Third Edition has been extensively updated, including a discussion of the physiological basis of fMRI and coverage of ethical and methodological controversies. Example are drawn from both seminal historical work and cutting-edge current research.

Magnetic Resonance Imaging: Recording, Reconstruction and Assessment gives a detailed overview of magnetic resonance imaging (MRI), along with its applications and challenges. The book explores the abnormalities in internal human organs using MRI techniques while also featuring case studies that illustrate measures used. In addition, it explores precautionary measures used during MRI based imaging, the selection of appropriate contrast agents, and the selection of the appropriate modality during the image registration. Sections introduce medical imaging, the use of MRI in brain, cardiac, lung and kidney detection, and also discuss both 2D and 3D imaging techniques and various MRI modalities. This volume will be of interest to researchers, engineers and medical professionals involved in the development and use of MRI systems.

Through numerous examples, the principles of the relationship between chemical structure and the NMR spectrum are developed in a logical, step-by-step fashion * Includes examples and exercises based on real NMR data including full 600 MHz one- and two-dimensional datasets of sugars, peptides, steroids and natural products * Includes detailed solutions and explanations in the text for the numerous examples and problems and also provides large, very detailed and annotated sets of NMR data for use in understanding the material * Describes both simple aspects of solution-state NMR of small molecules as well as more complex topics not usually covered in NMR books such as complex splitting patterns, weak long-range couplings, spreadsheet analysis of strong coupling patterns and resonance structure analysis for prediction of chemical shifts * Advanced topics include all of the common two-dimensional experiments (COSY, ROESY, NOESY, TOCSY, HSQC, HMBC) covered strictly from the point of view of data interpretation, along with tips for parameter settings

In the past few decades, Magnetic Resonance Imaging (MRI) has become an indispensable tool in modern medicine, with MRI systems now available at every major hospital in the developed world. But for all its utility and prevalence, it is much less commonly understood and less readily explained than other common medical imaging techniques. Unlike optical, ultrasonic, X-ray (including CT), and nuclear medicine-based imaging, MRI does not rely primarily on simple transmission and/or reflection of energy, and the highest achievable resolution in MRI is orders of magnitude smaller that the smallest wavelength involved. In this book, MRI will be explained with emphasis on the magnetic fields required, their generation, their concomitant electric fields, the various interactions of all these fields with the subject being imaged, and the implications of these interactions to image quality and patient safety. Classical electromagnetics will be used to describe aspects from the fundamental phenomenon of nuclear precession through signal detection and MRI safety. Simple explanations and Illustrations combined with pertinent equations are designed to help the reader rapidly gain a fundamental understanding and an appreciation of this technology as it is used today, as well as ongoing advances that will increase its value in the future. Numerous references are included to facilitate further study with an emphasis on areas most directly related to electromagnetics.

The Mayo Clinic Guide to Magnetic Resonance Imaging, Second Edition, is an updated version of the popular first edition of the same title. This handy reference text and soon to be classic text is designed to educate physicists, technologists and clinicians in the basics of cardiac MRI. A significantly expanded and reworked clinical imaging section provides numerous imaging protocols for the most commonly indicated cardiac MRI examinations as well as a plethora of well illustrated and described clinical examples. This text is a must have for anyone interested in developing their own cardiovascular MR imaging practice or advancing their existing skills. The addition of case-based questions and answers add a new dimension to this expanded second edition. This print edition of Mayo Clinic Guide to Cardiac Magnetic Resonance Imaging comes with a year's access to the online version on Oxford Medicine Online. By activating your unique access code, you can read and annotate the full text online, follow links from the references to primary research materials, and view, enlarge and download all the figures and tables.

This book presents the basic principles and new and emergent clinical applications of BOLD fMRI. It describes the physical principles of BOLD fMRI imaging and reviews scanning methodologies, data analysis, challenges and limitations of BOLD fMRI, neurovascular uncoupling, and functional connectivity. The book also explores current and future clinical applications of BOLD fMRI in the fields of language, memory, fMRI WADA, visual pathway, brain mapping of eloquent cortex, pediatrics, auditory pathways, epilepsy, psychiatric disorders, neurodegenerative disorders, pharmacological applications, and cognitive neuroscience. It concludes with a discussion of BOLD fMRI paradigms that can be used for clinical and cognitive experiments. Derived from Faro, Mohamed, Law, and Ulmer's Functional Neuroradiology: Principles and Applications, this book is a valuable resource for neurologists, cognitive neuroscientists, and neuroradiologists.

Written by authors from one of Asia's premier ophthalmology institutes the purpose of this atlas is to provide ophthalmologists and other physicians concerned with eye diseases with a carefully selected collection of quality illustrations that review the spectrum of diseases commonly seen in Neuro-ophthalmic practice.

The idea of using the enormous potential of magnetic resonance imaging (MRI) not only for diagnostic but also for interventional purposes may seem obvious, but it took major efforts by engineers, physicists, and clinicians to come up with dedicated interventional techniques and scanners, and improvements are still ongoing. Since the inception of interventional MRI in the mid-1990s, the numbers of settings, techniques, and clinical applications have increased dramatically. This state of the art book covers all aspects of interventional MRI. The more technical contributions offer an overview of the fundamental ideas and concepts and present the available instrumentation. The richly illustrated clinical contributions, ranging from MRI-guided biopsies to completely MRI-controlled therapies in various body regions, provide detailed information on established and emerging applications and identify future trends and challenges.

Based on the 1st edition this 2nd edition volume provides a completely revised comprehensive overview of the current state of the development in magnetic resonance (MR) vascular imaging. The basic principles and technical features of MR angiography are outlined, consideration being given to both flow-dependent and flow-independent contrast-enhanced approaches. Specific chapters focus on image display techniques, blood flow quantification, hardware configurations, and the limitations and artifacts of MR angiography. The well-established approach of providing a clinical overview of MR angiography in different vascular areas has been continued, with the presentation of a large number of and representative MR angiograms based on current acquisition techniques. Suitable examination protocols for different vascular regions and lesions are described to facilitate correct application of the technique. Systematic comparison is made with other vascular imaging techniques.

The underlying physics of magnetic resonance imaging is a topic of considerable importance since a basic understanding is necessary to accurately interpret and generate high quality MR images. Yet it can be a challenging topic in spite of the best efforts of both teachers and students of the subject. Practical MR Physics reviews the basic principles of MR using familiar language and explains the causes of common imaging artifacts and pitfalls. The book will also be a helpful guide during review of clinical cases since the reader can look up specific imaging artifacts or pitfalls in the index. Featuring over 375 high quality images, numerous case examples, and concise, clinically oriented discussion of the physics behind the images, Practical MR Physics is an ideal resource for anyone who works in the field of MR imaging.

The author of this book has been contributing to developments of an electron paramagnetic resonance (EPR) imaging system and its applications for more than 10 years. This system was designed for EPR measurements of experimental animals such as rats and mice, and its applications were mainly for biological researches. Thus, a lot of parameters to design an EPR imaging system are determined on the assumption that this system can be used for in vivo studies. The main aim of performing in vivo EPR measurements is to estimate in vivo reducing ability that cannot be obtained by other measuring methods at present. In this book, before main chapters about EPR imaging, this aim and specifications of apparatuses for achieving this aim are stated as a background. After description of instrumental components of an in vivo spectrometer, a theory, instruments, data processing, and applications of EPR imaging are explained. In the chapters about instruments and data processing, their details are described so that one can build the apparatus and obtain data. In the chapter about applications, examples of in vivo estimation of reducing ability in experimental models of some diseases are presented. In the last chapter, an explanation about region-selected intensity determination (RSID), a novel method that allows estimation of in vivo reducing ability at a selected anatomical region without complications of previous EPR imaging method, is stated.

Whether you are a resident, practicing radiologist, or new fellow, this authoritative resource offers expert guidance on all the essential information you need to approach musculoskeletal MRI and recognize abnormalities. The updated second edition features new illustrations to include the latest protocols as well as images obtained with 3 Tesla (T) MRI. See normal anatomy, common abnormalities, and diseases presented in a logical organization loaded with practical advice, tips, and pearls for easy comprehension. Follows a template that includes discussion of basic technical information, as well as the normal and abnormal appearance of each small unit that composes each joint so you can easily find and understand the information you need. Depicts both normal and abnormal anatomy, as well as disease progression, through more than 600 detailed images. Includes only the essential information so you get all you need to perform quality musculoskeletal MRI without having to wade through too many details. Presents the nuances that can be detected with 3 Tesla MRI so you can master this new technology Includes "how to" technical information on updated protocols for TMJ, shoulder, elbow, wrist/hand, spine, hips and pelvis, knee, and foot and ankle. Features information boxes throughout the text that highlight key information for quick review of pertinent material.

Magnetic Resonance Imaging, not so long ago a diagnostic tool of last resort, has become pervasive in the landscape of consumer medicine; images of the forbidding tubes, with their promises of revelation, surround us in commercials and on billboards. Magnetic Appeal offers an in-depth exploration of the science and culture of MRI, examining its development and emergence as an imaging technology, its popular appeal and acceptance, and its current use in health care.

Understood as modern and uncontroversial by health care professionals and in public discourse, the importance of MRI or its supposed infallibility has rarely been questioned. In Magnetic Appeal, Kelly A. Joyce shows how MRI technology grew out of serendipitous circumstances and was adopted for reasons having little to do with patient safety or evidence of efficacy. Drawing on interviews with physicians and MRI technologists, as well as ethnographic research conducted at imaging sites and radiology conferences, Joyce demonstrates that current beliefs about MRI draw on cultural ideas about sight and technology and are reinforced by health care policies and insurance reimbursement practices. Moreover, her unsettling analysis of physicians' and technologists' work practices lets readers consider that MRI scans do not reveal the truth about the body as is popularly believed, nor do they always lead to better outcomes for patients. Although clearly a valuable medical technique, MRI technology cannot necessarily deliver the health outcomes ascribed to it.

Magnetic Appeal also addresses broader questions about the importance of medical imaging technologies in American culture and medicine. These technologies, which include ultrasound, X-ray, and MRI, are part of a larger trend in which visual representations have become central to American health, identity, and social relations."

Magnetic resonance systems are used in almost every academic and industrial chemistry, physics and biochemistry department, as well as being one of the most important imaging modalities in clinical radiology. The design of such systems has become increasingly sophisticated over the years. Static magnetic fields increase continuously, large-scale arrays of receive elements are now ubiquitous in clinical MRI, cryogenic technology has become commonplace in high resolution NMR and is expanding rapidly in preclinical MRI, specialized high strength magnetic field gradients have been designed for studying the human connectome, and the commercial advent of ultra-high field human imaging has required new types of RF coils and static shim coils together with extensive electromagnetic simulations to ensure patient safety. This book covers the hardware and engineering that constitutes a magnetic resonance system, whether that be a high-resolution liquid or solid state system for NMR spectroscopy, a preclinical system for imaging animals or a clinical system used for human imaging. Written by a team of experts in the field, this book provides a comprehensive and instructional look at all aspects of current magnetic resonance technology, as well as outlooks for future developments.

MAGNETIC RESONANCE IMAGING
Mathematical Foundations and Applications
By Walter J. Schempp
As magnetic resonance imaging (MRI) continues to transform medical diagnostics and the study of the brain, the necessity for a more precise description of this important clinical tool is increasingly evident. A mathematical understanding of MRI and the related imaging modalities of functional MRI and NMR spectroscopy can greatly improve many scientific and medical endeavors, from the quality of scans in the tomographic slices and their semantic interpretations to minimally invasive neurosurgery and research in cognitive neuroscience.
Magnetic Resonance Imaging advances a coherent mathematical theory of MRI and presents for the first time a real-world application of non-commutative Fourier analysis. Emphasizing the interdisciplinary nature of clinical MRI, this book offers an intriguing look at the geometric principles underlying the quantum phenomena of biomedical research. Author Walter J. Schempp, widely respected among mathematicians and neuro-network scientists alike, includes in this lucid, readable text:
* The historical and phenomenological aspects of NMR spectroscopy and clinical MRI
* A mathematical approach to the structure-function problem in clinical MRI
* Detailed descriptions of applications to medical diagnostics
* Photographs illustrating the superior contrast and spatial resolution achieved by MRI
* An extensive list of references.
Magnetic Resonance Imaging introduces clinical and mathematical concepts gradually and deliberately, making the complex procedure of MRI accessible to professionals in all areas of neuroscience and neurology, as well as those in mathematics, engineering, radiology, and physics.

MR perfusion imaging is an area of major research interest and rapid clinical growth. Clinical Perfusion MRI: Techniques and Applications provides a concise and comprehensive review of the principles and applications of the field, covering dynamic susceptibility contrast, dynamic contrast enhancement, and arterial spin labeling imaging techniques. Principles of blood-volume and oxygenation imaging are included. The clinical applications of perfusion imaging in neurological disease and neuroscience are discussed - major topics including its use in imaging cerebrovascular disease and brain tumors and other neurological and neurodegenerative disorders. Non-neurologic applications are also covered with chapters on cardiac disease, breast cancer and other organ systems. Use of MR perfusion imaging in pediatrics is also discussed. Throughout the book case reports are included illustrating representative clinical examples. This book will be of interest to any clinician who uses MR perfusion imaging in their clinical practice, as well as researchers in the field of MRI.

Magnetic resonance imaging (MRI) is a technique used in biomedical imaging and radiology to visualize internal structures of the body. Because MRI provides excellent contrast between different soft tissues, the technique is especially useful for diagnostic imaging of the brain, muscles, and heart. In the past 20 years, MRI technology has improved significantly with the introduction of systems up to 7 Tesla (7 T) and with the development of numerous post-processing algorithms such as diffusion tensor imaging (DTI), functional MRI (fMRI), and spectroscopic imaging. From these developments, the diagnostic potentialities of MRI have improved impressively with an exceptional spatial resolution and the possibility of analyzing the morphology and function of several kinds of pathology. Given these exciting developments, the Magnetic Resonance Imaging Handbook: Image Principles, Neck, and the Brain is a timely addition to the growing body of literature in the field. Covering MRI from fundamentals to practice, this comprehensive book: Discusses the clinical benefits of diagnosing human pathologies using MRI Explains the physical principles of MRI and how to use the technique correctly Highlights each organ's anatomy and pathological processes with high-quality images Examines the protocols and potentialities of advanced MRI scanners such as 7 T systems Includes extensive references at the end of each chapter to enhance further study Thus, the Magnetic Resonance Imaging Handbook: Image Principles, Neck, and the Brain provides radiologists and imaging specialists with a valuable, state-of-the-art reference on MRI.

Arterial Spin Labeling (ASL) is an increasingly popular tool to study the brain. What sets it apart from other neuroimaging methods is the combination of quantitative measurements of a physiologically well-defined process, namely perfusion, and a completely non-invasive acquisition methodology. Cerebral perfusion is a critical component to brain health, as it is the primary means to deliver nutrients to support brain function as well as clearing waste products. Hence it is a useful quantity to study in disease where changes in perfusion can indicate regions of the brain that are pathological. Likewise changes in perfusion can be indicative of greater demand for nutrients, such as might be required in response to an increase in neuronal activity. With the advent of a consensus by the ASL community on good practice and a recommendation on robust methods for ASL data collection, more and more researchers are now able to access and use ASL. Despite the technological advances, ASL remains a technique with a low signal to noise ratio. This makes the wise choice of the appropriate analysis methods more important. The aim of this primer is to equip someone new to the field of perfusion imaging and ASL with the knowledge not only to make good choices about ASL acquisition and analysis, but also to understand what choices they are making and why. Examples of analysis applied to real data are given throughout the text and instructions on how to reproduce the analyses are illustrated on the primer website. Written to provide a stand-alone introduction to perfusion qualification using ASL, this primer also works with other texts in the Oxford Neuroimaging Primers series to provide a comprehensive overview of the increasingly influential field of neuroimaging.

Over the past decade, fluorine (19F) magnetic resonance imaging (MRI) has garnered significant scientific interest in the biomedical research community owing to the unique properties of fluorinated materials and the 19F nucleus. Fluorine has an intrinsically sensitive nucleus for MRI. There is negligible endogenous 19F in the body and thus there is no background signal. Fluorine-containing compounds are ideal tracer labels for a wide variety of MRI applications. Moreover, the chemical shift and nuclear relaxation rate can be made responsive to physiology via creative molecular design. This book is an interdisciplinary compendium that details cutting-edge science and medical research in the emerging field of 19F MRI. Edited by Ulrich Floegel and Eric Ahrens, two prominent MRI researchers, this book will appeal to investigators involved in MRI, biomedicine, immunology, pharmacology, probe chemistry, and imaging physics.

An essential guide to honing and developing skills in the review of musculoskeletal MRI studies Designed specifically for orthopedic surgeons involved in the review of musculoskeletal MRIs, this book enables clinicians to develop a systematic approach to the interpretation of MRI studies. It provides clinicians with a solid understanding of essential concepts, including the physics of MRI, various pulse sequences available for obtaining an MRI, and normal MRI anatomy and contains chapters on special considerations for imaging articular cartilage and soft-tissue and bone tumors, as well as advanced techniques such as MR arthrography and MR angiography, correlation with other imaging modalities, and safety issues. Features: More than 700 MRIs and instructive illustrations to highlight key concepts related to normal anatomy and pathologic processes Practical discussion of how other imaging modalities correlate with MRI Clinical insights from leading orthopedic surgeons and radiologists An ideal resource for orthopedic surgeons, residents, and fellows, this book provides essential instruction on how to approach MRI studies in everyday practice. With its practical coverage of clinical concepts, this book will also serve as a valuable reference for radiologists, rheumatologists, primary care physicians, and other specialists who care for patients with musculoskeletal conditions.

Clinical MR Neuroimaging, second edition, provides radiologists, neuroscientists and researchers with a clear understanding of each physiological MR methodology and their applications to the major neurological diseases. Section 1 describes the physical principles underlying each technique and their associated artefacts and pitfalls. Subsequent sections review the application of MRI in a range of clinical disorders: cerebrovascular disease, neoplasia, infection/inflammation/demyelination disorders, seizures, psychiatric/neurodegenerative conditions, and trauma. This new edition includes all recent advances and applications, with greatly increased coverage of permeability imaging, susceptibility imaging, iron imaging, MR spectroscopy and fMRI. All illustrations are completely new, taking advantage of the latest scan capabilities to give images of the highest possible quality. In addition, over 35 new case studies have been included. Editors and contributors are the leading neuroimaging experts worldwide; their unique combination of technical knowledge and clinical expertise makes Clinical MR Neuroimaging the leading text on the subject.

In this autobiography, Sir Peter Mansfield describes his life from war time childhood that initially sparked his interest in physics to his work in magnetic resonance imaging (MRI) that eventually led to the award of the Nobel Prize in 2003. Peter Mansfield grew up in London, but was evacuated to Devon during the blitz and following the V1 and V2 attacks on London. At the end of hostilities, he worked briefly in the printing industry before deciding to pursue his real interests in science by joining the Rocket Propulsion Department at Westcott near Aylesbury. Following a period of National Service and his studies at Queen Mary College, University of London, he married and moved to the USA for two years, returning in 1964 as a Lecturer in Physics at the University of Nottingham. In 1972 he spent a sabbatical period in Heidelberg, and during this period corresponded with his student, Peter Grannell, in Nottingham on the novel idea of magnetic resonance imaging. This led to his first paper on MRI which was presented at the first Specialised Colloque Ampere in 1973. During this period, he demonstrated how the MRI radio signals can be analysed and turned into images of the body. In 2003 the Nobel Prize in Physiology or Medicine was awarded jointly to Sir Peter and Paul Lauterbur for their crucial achievements in the development of MRI.

Encyclopedia of NMR - Encompassing all relevant areas for NMR science and technology and applications in physics, chemistry and biology

This new 10 volume set captures every aspect of the interdisciplinary nature of magnetic resonance and provides the most complete and up-to-date source in the field. It includes many articles from the print editions of "Encyclopedia of Nuclear Magnetic Resonance "and recent "EMR Books," as well as new and updated articles published online in the "Encyclopedia of Magnetic Resonance."

Covering key developments such as:

- New techniques

- Protein structures

- Dynamics of molecular processes

- Characterization of materials, polymers and nano-materials

- NMR crystallography

- Solid biological samples such as membranes

Add Encyclopedia of NMR to your bookshelf for...

- Easy to access information - Covering all the techniques and applications in general NMR areas in an A-Z format

- Use as a learning tool - Revisit basics as well as get up-to-date with the latest methods and thinking

- Use in day-to-day work in the lab - Discover information on new techniques and applications, take advantage of useful hints and tips

- Short biographies of contributing authors - Showing the link between the career and the expertise of the contributing scientists

- Perspectives and personal recollections - A look back at major adventures, evolution and developments that have shaped the field, alongside leading researchers who share their personal involvements with NMR and MRI

Encyclopedia of NMR includes:

- Many original and updated articles from the print edition of "Encyclopedia of Nuclear Magnetic Resonance" (1996)

- Articles from "EMR Books" - special handbooks covering hot topic areas

- Additional NMR-focused articles published online in the "Encyclopedia ""of Magnetic Resonance" - the updating online resourceTake advantage of the introductory price: 2500 / 3220 / $3750, valid until 28th February 2013. Prices will revert to 3067 / 3940 / $4600 thereafter.

Subscribe to the updating online edition -" eMagRes"

Available online for libraries and institutions as "eMagRes" (formerly published as the "Encyclopedia of Magnetic Resonance)," the online edition relaunched in January 2013with a range of new features which makes the site more user-friendly and more attractive to both the medical MRI community and to the molecular chemistry, physics and biology communities.

This reference work first published online in 2007, and since that date has been updated four times a year with approximately 10% new or updated content each year across a wide range of topics. As part of the relaunch the content structure has been revised to aid quick navigation for both the medical MRI community and the molecular chemistry, physics and biology communities to articles of interest.

Find out more about the online edition here: www.wileyonlinelibrary.com/ref/eMagRes

This is the first textbook dedicated to CEST imaging and covers the fundamental principles of saturation transfer, key features of CEST agents that enable the production of imaging contrast, and practical aspects of preparing image-acquisition and post-processing schemes suited for in vivo applications. CEST is a powerful MRI contrast mechanism with unique features, and the rapid expansion it has seen over the past 15 years since its original discovery in 2000 has created a need for a graduate-level handbook describing all aspects of pre-clinical, translational, and clinical CEST imaging. The book provides an illustrated historical perspective by leaders at the five key sites who developed CEST imaging, from the initial saturation transfer NMR experiments performed in the 1960s in Stockholm, Sweden, described by Sture Forsen, to the work on integrating the basic principles of CEST into imaging by Robert Balaban, Dean Sherry, Silvio Aime, and Peter van Zijl in the United States and Italy. The editors, Drs. Michael T. McMahon, Assaf A. Gilad, Jeff W. M. Bulte, and Peter C. M. van Zijl, have been pioneers developing this field at the Johns Hopkins University School of Medicine and the Kennedy Krieger Institute including contributions to Nature Medicine, Nature Biotechnology, Nature Materials, and the Proceedings of the National Academy of Sciences. As recognition for their initial development of the field, Drs. van Zijl and Balaban were awarded the Laukien Prize in April 2016, established in 1999 to honor the memory of Professor Gunther Laukien, a co-founder of Bruker Biospin GmbH.