Encyclopedia of NMR - Encompassing all relevant areas for NMR science and technology and applications in physics, chemistry and biology

This new 10 volume set captures every aspect of the interdisciplinary nature of magnetic resonance and provides the most complete and up-to-date source in the field. It includes many articles from the print editions of "Encyclopedia of Nuclear Magnetic Resonance "and recent "EMR Books," as well as new and updated articles published online in the "Encyclopedia of Magnetic Resonance."

Covering key developments such as:

- New techniques

- Protein structures

- Dynamics of molecular processes

- Characterization of materials, polymers and nano-materials

- NMR crystallography

- Solid biological samples such as membranes

Add Encyclopedia of NMR to your bookshelf for...

- Easy to access information - Covering all the techniques and applications in general NMR areas in an A-Z format

- Use as a learning tool - Revisit basics as well as get up-to-date with the latest methods and thinking

- Use in day-to-day work in the lab - Discover information on new techniques and applications, take advantage of useful hints and tips

- Short biographies of contributing authors - Showing the link between the career and the expertise of the contributing scientists

- Perspectives and personal recollections - A look back at major adventures, evolution and developments that have shaped the field, alongside leading researchers who share their personal involvements with NMR and MRI

Encyclopedia of NMR includes:

- Many original and updated articles from the print edition of "Encyclopedia of Nuclear Magnetic Resonance" (1996)

- Articles from "EMR Books" - special handbooks covering hot topic areas

- Additional NMR-focused articles published online in the "Encyclopedia ""of Magnetic Resonance" - the updating online resourceTake advantage of the introductory price: 2500 / 3220 / $3750, valid until 28th February 2013. Prices will revert to 3067 / 3940 / $4600 thereafter.

Subscribe to the updating online edition -" eMagRes"

Available online for libraries and institutions as "eMagRes" (formerly published as the "Encyclopedia of Magnetic Resonance)," the online edition relaunched in January 2013with a range of new features which makes the site more user-friendly and more attractive to both the medical MRI community and to the molecular chemistry, physics and biology communities.

This reference work first published online in 2007, and since that date has been updated four times a year with approximately 10% new or updated content each year across a wide range of topics. As part of the relaunch the content structure has been revised to aid quick navigation for both the medical MRI community and the molecular chemistry, physics and biology communities to articles of interest.

Find out more about the online edition here: www.wileyonlinelibrary.com/ref/eMagRes

Magnetic resonance imaging (MRI) is a technique used in biomedical imaging and radiology to visualize internal structures of the body. Because MRI provides excellent contrast between different soft tissues, the technique is especially useful for diagnostic imaging of the brain, muscles, and heart. In the past 20 years, MRI technology has improved significantly with the introduction of systems up to 7 Tesla (7 T) and with the development of numerous post-processing algorithms such as diffusion tensor imaging (DTI), functional MRI (fMRI), and spectroscopic imaging. From these developments, the diagnostic potentialities of MRI have improved impressively with an exceptional spatial resolution and the possibility of analyzing the morphology and function of several kinds of pathology. Given these exciting developments, the Magnetic Resonance Imaging Handbook: Image Principles, Neck, and the Brain is a timely addition to the growing body of literature in the field. Covering MRI from fundamentals to practice, this comprehensive book: Discusses the clinical benefits of diagnosing human pathologies using MRI Explains the physical principles of MRI and how to use the technique correctly Highlights each organ's anatomy and pathological processes with high-quality images Examines the protocols and potentialities of advanced MRI scanners such as 7 T systems Includes extensive references at the end of each chapter to enhance further study Thus, the Magnetic Resonance Imaging Handbook: Image Principles, Neck, and the Brain provides radiologists and imaging specialists with a valuable, state-of-the-art reference on MRI.

This is the first textbook dedicated to CEST imaging and covers the fundamental principles of saturation transfer, key features of CEST agents that enable the production of imaging contrast, and practical aspects of preparing image-acquisition and post-processing schemes suited for in vivo applications. CEST is a powerful MRI contrast mechanism with unique features, and the rapid expansion it has seen over the past 15 years since its original discovery in 2000 has created a need for a graduate-level handbook describing all aspects of pre-clinical, translational, and clinical CEST imaging. The book provides an illustrated historical perspective by leaders at the five key sites who developed CEST imaging, from the initial saturation transfer NMR experiments performed in the 1960s in Stockholm, Sweden, described by Sture Forsen, to the work on integrating the basic principles of CEST into imaging by Robert Balaban, Dean Sherry, Silvio Aime, and Peter van Zijl in the United States and Italy. The editors, Drs. Michael T. McMahon, Assaf A. Gilad, Jeff W. M. Bulte, and Peter C. M. van Zijl, have been pioneers developing this field at the Johns Hopkins University School of Medicine and the Kennedy Krieger Institute including contributions to Nature Medicine, Nature Biotechnology, Nature Materials, and the Proceedings of the National Academy of Sciences. As recognition for their initial development of the field, Drs. van Zijl and Balaban were awarded the Laukien Prize in April 2016, established in 1999 to honor the memory of Professor Gunther Laukien, a co-founder of Bruker Biospin GmbH.

The definitive guide to MRI for musculoskeletal abnormalities Differential Diagnosis in Musculoskeletal MRI is a unique desk reference offering extensive descriptions of MRI findings that enable radiologists to more easily diagnose a wide range of musculoskeletal conditions. The authors have placed the most essential content covering etiologic, clinical, and pathological aspects in tabular format to assist readers in quickly and efficiently obtaining the information they need. Features: More than 2,000 state-of-the-art images covering the features for both common and rare musculoskeletal conditions Authors provide a practical approach to MRI evaluation and differential diagnosis selection Differential diagnosis tables are based on anatomic locations of lesions This practical reference is an invaluable tool that practicing radiologists, residents, and fellows will use to diagnose both common and rare lesions as well as other disorders of the musculoskeletal system. It is an excellent guide for use in daily practice as well as a comprehensive exam preparation tool.

The value of MR imaging for the evaluation of musculoskeletal system disorders cannot be over-stated. It is the only imaging modality that enables visualization of all components of the joints within single examinations. Yet, given the bewildering variety of possible sequence parameters, with and without contrast medium, acquiring and interpreting MR images with confidence is a challenge, requiring experience usually only gained after examining 1000s of studies with a careful systematic approach. Like the First Edition, the Second Edition of MRI of the Musculoskeletal System assists the radiologist in acquiring the most reliable and complete imaging information, so as to achieve a high degree of diagnostic certainty quickly and efficiently. Key Features: More than 2000 MR images of reference quality, the majority new for this edition Drawings, where helpful, aid the reader in identifying and delineating normal and pathological entities Includes all the latest advanced techniques: MR neurography and myelography, diffusion imaging, quantitative MRI, mDIXON, and more All MR exams described fully, with choice of sequence, positioning, choice of coils, when/how to use contrast, protocols Discussions of possible errors in interpretation Comparison of MR imaging with other modalities Tables expand and organize information on sequence parameters and differential diagnoses More than just an authoritative reference, Vahlensieck's MRI of the Musculoskeletal System is the ideal practical helper to accompany the radiologist at the workstation on a daily basis.

The author of this book has been contributing to developments of an electron paramagnetic resonance (EPR) imaging system and its applications for more than 10 years. This system was designed for EPR measurements of experimental animals such as rats and mice, and its applications were mainly for biological researches. Thus, a lot of parameters to design an EPR imaging system are determined on the assumption that this system can be used for in vivo studies. The main aim of performing in vivo EPR measurements is to estimate in vivo reducing ability that cannot be obtained by other measuring methods at present. In this book, before main chapters about EPR imaging, this aim and specifications of apparatuses for achieving this aim are stated as a background. After description of instrumental components of an in vivo spectrometer, a theory, instruments, data processing, and applications of EPR imaging are explained. In the chapters about instruments and data processing, their details are described so that one can build the apparatus and obtain data. In the chapter about applications, examples of in vivo estimation of reducing ability in experimental models of some diseases are presented. In the last chapter, an explanation about region-selected intensity determination (RSID), a novel method that allows estimation of in vivo reducing ability at a selected anatomical region without complications of previous EPR imaging method, is stated.

Magnetic Resonance Imaging, not so long ago a diagnostic tool of last resort, has become pervasive in the landscape of consumer medicine; images of the forbidding tubes, with their promises of revelation, surround us in commercials and on billboards. Magnetic Appeal offers an in-depth exploration of the science and culture of MRI, examining its development and emergence as an imaging technology, its popular appeal and acceptance, and its current use in health care.

Understood as modern and uncontroversial by health care professionals and in public discourse, the importance of MRI or its supposed infallibility has rarely been questioned. In Magnetic Appeal, Kelly A. Joyce shows how MRI technology grew out of serendipitous circumstances and was adopted for reasons having little to do with patient safety or evidence of efficacy. Drawing on interviews with physicians and MRI technologists, as well as ethnographic research conducted at imaging sites and radiology conferences, Joyce demonstrates that current beliefs about MRI draw on cultural ideas about sight and technology and are reinforced by health care policies and insurance reimbursement practices. Moreover, her unsettling analysis of physicians' and technologists' work practices lets readers consider that MRI scans do not reveal the truth about the body as is popularly believed, nor do they always lead to better outcomes for patients. Although clearly a valuable medical technique, MRI technology cannot necessarily deliver the health outcomes ascribed to it.

Magnetic Appeal also addresses broader questions about the importance of medical imaging technologies in American culture and medicine. These technologies, which include ultrasound, X-ray, and MRI, are part of a larger trend in which visual representations have become central to American health, identity, and social relations."

As a practical reference guide for designing and performing experiments, this book focuses on the five most common classes of contrast agents for MRI namely gadolinium complexes, chemical exchange saturation transfer agents, iron oxide nanoparticles, manganese complexes and fluorine contrast agents. It describes how to characterize and evaluate them and for each class, a description of the theory behind their mechanisms is discussed briefly to orient the new reader. Detailed subchapters discuss the different physical chemistry methods used to characterize them in terms of their efficacy, safety and in vivo behavior. Important consideration is also given to the different physical properties that affect the performance of the contrast agents. The editors and contributors are at the forefront of research in the field of MRI contrast agents and this unique, cutting edge book is a timely addition to the literature in this area.

This book details the latest research on magnetic resonance (MRI) tagging technology related to heart mechanics. The book compare and contrast different tagging techniques, explain different imaging sequences and post processing algorithms, and associate the tagging techniques with different applications. It presents MRI techniques in chronological order, describing how the drawbacks of a certain technique led to the invention of the next one.

Based on research and clinical trials, this book details the latest research in magnetic resonance imaging (MRI) tagging technology related to heart mechanics. It covers clinical applications and examines future trends, providing a guide for future uses of MRI technology for studying heart mechanics.

Learn the fundamental principles and clinical applications of the diagnostic and risk assessment imaging test of choice for prostate cancer: prostate MRI Although prostate cancer is the second leading cause of cancer death in men in the USA, it can be treated successfully if detected early. Disease management has gradually changed to a paradigm that relies on close monitoring through active surveillance in select patients, as well as ongoing refinements in treatment interventions, including minimally invasive procedures. This has resulted in a critical need for a more exacting methodology for performing targeted biopsies, assessing risk levels, and devising treatment strategies. Prostate MRI has emerged as the most precise, state-of-the-art imaging modality for prostate cancer diagnosis and management, thereby creating an immediate demand for radiologists to become proficient in its use. Conceived and edited by a leading authority, with contributions from renowned experts in the field, MRI of the Prostate: A Practical Approach is the first book to tackle this important topic. It provides an overview of the fundamentals of prostate MRI acquisition, interpretation, and reporting. Readers will benefit from a wide range of insightful perspectives gleaned from years of hands-on experience. Key Highlights Prostate Imaging Reporting and Data System (PI-RADS) for prostate MRI interpretation and cancer risk scoring Clinical pearls on the optimization and application of prostate MRI for risk assessment, disease staging, MRI-targeted biopsy, recurrent disease, and active surveillance The emerging utilization of PET and PET/MRI for primary prostate cancer evaluation More than 700 illustrations with one entirely image-based chapter featuring educational case studies Radiologists will learn how to optimally perform and interpret prostate MRI, and referring physicians will learn to integrate it into day-to-day practice. This book is an essential resource for radiologists and radiology residents, as well as urologists, oncologists, MRI technicians, and other medical practitioners who treat patients with genitourinary disorders.

Magnetic resonance imaging (MRI) is a technique used in biomedical imaging and radiology to visualize internal structures of the body. Because MRI provides excellent contrast between different soft tissues, the technique is especially useful for diagnostic imaging of the brain, muscles, and heart. In the past 20 years, MRI technology has improved significantly with the introduction of systems up to 7 Tesla (7 T) and with the development of numerous post-processing algorithms such as diffusion tensor imaging (DTI), functional MRI (fMRI), and spectroscopic imaging. From these developments, the diagnostic potentialities of MRI have improved impressively with an exceptional spatial resolution and the possibility of analyzing the morphology and function of several kinds of pathology. Given these exciting developments, the Magnetic Resonance Imaging Handbook is a timely addition to the growing body of literature in the field. Comprised of three volumes, this comprehensive handbook: Covers the technology and practice of MRI from physical principles to cutting-edge applications Discusses MRI of the neck, brain, cardiovascular system, thorax, abdomen, pelvis, and musculoskeletal system Highlights each organ's anatomy and pathological processes with high-quality images Examines the protocols and potentialities of advanced MRI scanners such as 7 T systems Includes extensive references at the end of each chapter to enhance further study Thus, the Magnetic Resonance Imaging Handbook provides radiologists and imaging specialists with a valuable, state-of-the-art reference on MRI.

The field of magnetic resonance imaging (MRI) has developed rapidly over the past decade, benefiting greatly from the newly developed framework of compressed sensing and its ability to drastically reduce MRI scan times. MRI: Physics, Image Reconstruction, and Analysis presents the latest research in MRI technology, emphasizing compressed sensing-based image reconstruction techniques. The book begins with a succinct introduction to the principles of MRI and then: Discusses the technology and applications of T1rho MRI Details the recovery of highly sampled functional MRIs Explains sparsity-based techniques for quantitative MRIs Describes multi-coil parallel MRI reconstruction techniques Examines off-line techniques in dynamic MRI reconstruction Explores advances in brain connectivity analysis using diffusion and functional MRIs Featuring chapters authored by field experts, MRI: Physics, Image Reconstruction, and Analysis delivers an authoritative and cutting-edge treatment of MRI reconstruction techniques. The book provides engineers, physicists, and graduate students with a comprehensive look at the state of the art of MRI.

Drug-resistant epilepsy with negative MRI is frequently seen in patients considered for epilepsy surgery; however, clinical evaluation and surgical treatment is very complex and challenging. Advanced imaging techniques are needed to detect the location of the epileptogenic zone. In most cases, intracranial EEG recording is required to delineate the region of seizure onset - this carries some risks of major complications. Moreover, the borders between the recorded seizure onset and the location of important brain functions are often indistinct in MRI-negative epilepsy. Overall, the outcome of MRI-negative surgery is less favorable than that of MRI-positive surgery, but it can significantly improve with optimal management. Each chapter critically appraises the role and value of specific diagnostic and treatment techniques to address the challenges of MRI-negative epilepsy surgery. Authors critique evidence and share their expertise on the diagnostic options and surgical approaches that make epilepsy surgery possible and worthwhile in patients with this condition.

Body MR Imaging at 3.0 Tesla is a practical text enabling radiologists to maximise the benefits of high field 3T MR systems in a range of body applications. It explains the physical principles of MR imaging using 3T magnets, and the differences between 1.5T and 3T when applied extracranially. The book's organ-based approach focuses on optimized techniques, providing recommended protocols for the main vendors of 3T MRI systems. All major thoracic and abdominal organs are covered, including breast, heart, liver, pancreas, the GI tract, kidneys, prostate and female pelvic organs. Abdominal and pelvic MR angiography and MRCP are also discussed. Protocol optimization, appearance of artifacts and novel applications using 3T are emphasized. Written and edited by experts in the field, Body MR Imaging at 3.0 Tesla guides radiologists in optimizing imaging protocols for 3T MR systems, reducing artifacts and identifying the advantages of using 3T in body applications.

The popularity of magnetic resonance (MR) imaging in medicine is no mystery: it is non-invasive, it produces high quality structural and functional image data, and it is very versatile and flexible. Research into MR technology is advancing at a blistering pace, and modern engineers must keep up with the latest developments. This is only possible with a firm grounding in the basic principles of MR, and Advanced Image Processing in Magnetic Resonance Imaging solidly integrates this foundational knowledge with the latest advances in the field. Beginning with the basics of signal and image generation and reconstruction, the book covers in detail the signal processing techniques and algorithms, filtering techniques for MR images, quantitative analysis including image registration and integration of EEG and MEG techniques with MR, and MR spectroscopy techniques. The final section of the book explores functional MRI (fMRI) in detail, discussing fundamentals and advanced exploratory data analysis, Bayesian inference, and nonlinear analysis. Many of the results presented in the book are derived from the contributors' own work, imparting highly practical experience through experimental and numerical methods. Contributed by international experts at the forefront of the field, Advanced Image Processing in Magnetic Resonance Imaging is an indispensable guide for anyone interested in further advancing the technology and capabilities of MR imaging.

Demonstrates how MRS offers a useful tool for the noninvasive biochemical analysis of the brain. The book covers over 70 clinical cases and more than 100 spectra that enhance skills at interpreting MRS, including minimizing errors, highlighting artifacts, and expanding the clinical usefulness of this diagnostic modality.

Magnetic resonance spectroscopy (MRS) has been an important analytical tool in organic chemistry, biology, and materials science for more than a half-century. Now, recent advances in the clinical application of MRS are allowing radiologists to more effectively diagnose lymphoma, head and neck cancers, and brain tumors, as well as to understand metabolic brain anomalies such as stroke and dementia.

Clinical MR Spectroscopy: First Principles acquaints readers with the basic physics and chemistry of MRS while providing clear, practical guidelines for its clinical use. While most readers are likely to have had experience with MRI, this is not a prerequisite for understanding either the basic science or applied sections of the book.

Individual chapters address such topics as:

• The basic concepts of MRS
• Hardware and software requirements
• Techniques for localized spectroscopy
• Spectroscopy data processing
• The application of MRS in examining the brain, heart, muscles, and liver.

Clinical MR Spectroscopy: First Principles features numerous line drawings to clarify the basic science of MRS and images to illustrate its clinical utility. This concise and timely book provides an accessible but comprehensive resource for radiologists, MRI technologists, and radiology residents.

This book is a concise overview of MRI (magnetic resonance imaging) for brain, chest and abdominal disorders covering the very latest technologies and developments in the field. Beginning with an introduction to anatomy of these body systems, the following sections cover MR cholangiopancreatography, MRI of the female and male pelvis, and MR angiography. The atlas is enhanced by high quality MR images and tables with detailed descriptions to help clinicians understand complex anatomy. The comprehensive appendix provides a glossary of MRI terms and radiology measurement tables. Key Points Concise overview of MRI for brain, chest and abdomen Features sections on MR cholangiopancreatography, MRI of the pelvis, and MR angiography Comprehensive appendix provides glossary of terms and radiology measurement tables Includes high quality MR images and tables illustrating complex anatomy

This concise book explains the basic principles of magnetic resonance imaging.

Safety and Efficacy of Radiopharmaceuticals was established as a very important and comprehensive subject at the First Europe­ an Symposium on Radiopharmacy and Radiopharmaceuticals in Denmark in 1983. The interest in this subject has grown considerably since then due to the growing interest among national authorities to deal with radiopharmaceuticals. The introduction in recent years of nuclear medicine techniques based on radioactive labelled cells and on monoclonal antibodies has stressed the importance of a well functioning approval system for the clinical trial and use of new radiopharmaceuticals. The process of transferring the experience from the non radioactive drug field into the area of radiopharmaceuticals is still ongoing. International organisations such as the World Health Organisa­ tion is also including this into their quality assurance programme from both the radiopharmaceutical and the radiation hygiene point of view. In order to give an up-to date survey of these areas, experts were invited to prepare review papers under the following headings: Safety and Efficacy of Radiophar­ maceuticals with Emphasis on Biological Products, Radiophar­ macy/Radiation Hygiene, Legal Aspects of the Introduction of New Radiopharmaceuticals and some selected aspects of Good Radiopharmacy Practice.

Cardiovascular Magnetic Resonance Imaging (CMR) is one of the latest noninvasive imaging methods for cardiac disease. The aim of this book is to provide the reader with the technological background and clinical applications of current CMR imaging. Up-to-date and practical, Cardiovascular Magnetic Resonance Imaging will be of great use to cardiologists, radiologists, primary care physicians, MRI technologists, and other health care providers with interests in CMR.