Whether you are a resident, practicing radiologist, or new fellow, this authoritative resource offers expert guidance on all the essential information you need to approach musculoskeletal MRI and recognize abnormalities. The updated second edition features new illustrations to include the latest protocols as well as images obtained with 3 Tesla (T) MRI. See normal anatomy, common abnormalities, and diseases presented in a logical organization loaded with practical advice, tips, and pearls for easy comprehension. Follows a template that includes discussion of basic technical information, as well as the normal and abnormal appearance of each small unit that composes each joint so you can easily find and understand the information you need. Depicts both normal and abnormal anatomy, as well as disease progression, through more than 600 detailed images. Includes only the essential information so you get all you need to perform quality musculoskeletal MRI without having to wade through too many details. Presents the nuances that can be detected with 3 Tesla MRI so you can master this new technology Includes "how to" technical information on updated protocols for TMJ, shoulder, elbow, wrist/hand, spine, hips and pelvis, knee, and foot and ankle. Features information boxes throughout the text that highlight key information for quick review of pertinent material.

MAGNETIC RESONANCE IMAGING
Mathematical Foundations and Applications
By Walter J. Schempp
As magnetic resonance imaging (MRI) continues to transform medical diagnostics and the study of the brain, the necessity for a more precise description of this important clinical tool is increasingly evident. A mathematical understanding of MRI and the related imaging modalities of functional MRI and NMR spectroscopy can greatly improve many scientific and medical endeavors, from the quality of scans in the tomographic slices and their semantic interpretations to minimally invasive neurosurgery and research in cognitive neuroscience.
Magnetic Resonance Imaging advances a coherent mathematical theory of MRI and presents for the first time a real-world application of non-commutative Fourier analysis. Emphasizing the interdisciplinary nature of clinical MRI, this book offers an intriguing look at the geometric principles underlying the quantum phenomena of biomedical research. Author Walter J. Schempp, widely respected among mathematicians and neuro-network scientists alike, includes in this lucid, readable text:
* The historical and phenomenological aspects of NMR spectroscopy and clinical MRI
* A mathematical approach to the structure-function problem in clinical MRI
* Detailed descriptions of applications to medical diagnostics
* Photographs illustrating the superior contrast and spatial resolution achieved by MRI
* An extensive list of references.
Magnetic Resonance Imaging introduces clinical and mathematical concepts gradually and deliberately, making the complex procedure of MRI accessible to professionals in all areas of neuroscience and neurology, as well as those in mathematics, engineering, radiology, and physics.

Magnetic resonance imaging (MRI) is a technique used in biomedical imaging and radiology to visualize internal structures of the body. Because MRI provides excellent contrast between different soft tissues, the technique is especially useful for diagnostic imaging of the brain, muscles, and heart. In the past 20 years, MRI technology has improved significantly with the introduction of systems up to 7 Tesla (7 T) and with the development of numerous post-processing algorithms such as diffusion tensor imaging (DTI), functional MRI (fMRI), and spectroscopic imaging. From these developments, the diagnostic potentialities of MRI have improved impressively with an exceptional spatial resolution and the possibility of analyzing the morphology and function of several kinds of pathology. Given these exciting developments, the Magnetic Resonance Imaging Handbook: Image Principles, Neck, and the Brain is a timely addition to the growing body of literature in the field. Covering MRI from fundamentals to practice, this comprehensive book: Discusses the clinical benefits of diagnosing human pathologies using MRI Explains the physical principles of MRI and how to use the technique correctly Highlights each organ's anatomy and pathological processes with high-quality images Examines the protocols and potentialities of advanced MRI scanners such as 7 T systems Includes extensive references at the end of each chapter to enhance further study Thus, the Magnetic Resonance Imaging Handbook: Image Principles, Neck, and the Brain provides radiologists and imaging specialists with a valuable, state-of-the-art reference on MRI.

Over the past decade, fluorine (19F) magnetic resonance imaging (MRI) has garnered significant scientific interest in the biomedical research community owing to the unique properties of fluorinated materials and the 19F nucleus. Fluorine has an intrinsically sensitive nucleus for MRI. There is negligible endogenous 19F in the body and thus there is no background signal. Fluorine-containing compounds are ideal tracer labels for a wide variety of MRI applications. Moreover, the chemical shift and nuclear relaxation rate can be made responsive to physiology via creative molecular design. This book is an interdisciplinary compendium that details cutting-edge science and medical research in the emerging field of 19F MRI. Edited by Ulrich Floegel and Eric Ahrens, two prominent MRI researchers, this book will appeal to investigators involved in MRI, biomedicine, immunology, pharmacology, probe chemistry, and imaging physics.

An essential guide to honing and developing skills in the review of musculoskeletal MRI studies Designed specifically for orthopedic surgeons involved in the review of musculoskeletal MRIs, this book enables clinicians to develop a systematic approach to the interpretation of MRI studies. It provides clinicians with a solid understanding of essential concepts, including the physics of MRI, various pulse sequences available for obtaining an MRI, and normal MRI anatomy and contains chapters on special considerations for imaging articular cartilage and soft-tissue and bone tumors, as well as advanced techniques such as MR arthrography and MR angiography, correlation with other imaging modalities, and safety issues. Features: More than 700 MRIs and instructive illustrations to highlight key concepts related to normal anatomy and pathologic processes Practical discussion of how other imaging modalities correlate with MRI Clinical insights from leading orthopedic surgeons and radiologists An ideal resource for orthopedic surgeons, residents, and fellows, this book provides essential instruction on how to approach MRI studies in everyday practice. With its practical coverage of clinical concepts, this book will also serve as a valuable reference for radiologists, rheumatologists, primary care physicians, and other specialists who care for patients with musculoskeletal conditions.

Functional Magnetic Resonance Imaging provides a comprehensive introduction to fMRI. The Third Edition has been extensively updated, including a discussion of the physiological basis of fMRI and coverage of ethical and methodological controversies. Example are drawn from both seminal historical work and cutting-edge current research.

The opening chapter of The Essential Guide to Magnetic Resonance presents applications of Fluorine-19 Magnetic Resonance Imaging (19F MRI) in cancer research, tissue metabolomics, quantification of drug delivery, cellular tracking, tissue pH measurements and detection of 19F labeled cells. The authors review in vitro research applying 19F MRI and Magnetic Resonance Spectroscopy (MRS) to facilitate the synthesis, tracking and visualization of new fluorinated drug conjugates. 19F MRI also provides high contrast in vivo images due to the absence of an endogenous 19F signal, 100% natural abundance of 19F, and a chemical shift range of over 400 ppm. Afterwards, examples of current methods of magnetic resonance imaging (MRI) guided photodynamic therapy are presented. Recent development of MRI detectable nanoparticle constructs, magnetic resonance spectroscopy (MRS) sensors, gadolinium based photosensitizers and europium singlet oxygen probes are discussed. In addition, applications of Functional MRI using a blood oxygen dependent level (BOLD) MRI in monitoring photodynamic action are addressed, with the goal of informing researchers about the potential for using MRI guided photodynamic therapy and oxygen dosimetry. The applications of MRI within the sphere of pharmacy are analyzed; in particular, the use of MRI to track pharmaceuticals in vitro and in vivo noninvasively and monitoring their controlled-release. Functional MRI for noninvasive clinical brain imaging is explored as it is applied to studies of autism, schizophrenia, epilepsy Alzheimers disease, Parkinson's disease, traumatic brain injury and blood oxygenation-level dependent (BOLD) imaging of brain function. An overview of the scope of MRI as a diagnostic technique in neurology and in neurosurgery is also provided.

Clinical MR Neuroimaging, second edition, provides radiologists, neuroscientists and researchers with a clear understanding of each physiological MR methodology and their applications to the major neurological diseases. Section 1 describes the physical principles underlying each technique and their associated artefacts and pitfalls. Subsequent sections review the application of MRI in a range of clinical disorders: cerebrovascular disease, neoplasia, infection/inflammation/demyelination disorders, seizures, psychiatric/neurodegenerative conditions, and trauma. This new edition includes all recent advances and applications, with greatly increased coverage of permeability imaging, susceptibility imaging, iron imaging, MR spectroscopy and fMRI. All illustrations are completely new, taking advantage of the latest scan capabilities to give images of the highest possible quality. In addition, over 35 new case studies have been included. Editors and contributors are the leading neuroimaging experts worldwide; their unique combination of technical knowledge and clinical expertise makes Clinical MR Neuroimaging the leading text on the subject.

This book aims to provide a basic understanding of the principles of in vivo Magnetic Resonance Spectroscopy (MRS), a pioneer technique which is now finding increasing clinical uses in detection of cancer in an non-invasive manner and provide a comprehensive evaluation and assessment of the current status of MRS in the field of breast tumor detection. It also provides an updated, concise review on breast tumor pathology and MR imaging. It offers some introduction into the in vitro MRS and other future potential diagnostics in the field of breast tumours.

Magnetic resonance imaging (MRI), formerly referred to as magnetic resonance tomography (MRT) or nuclear magnetic resonance (NMR), is a method used to visualise the inside of living organisms as well as to detect the amount of bound water in geological structures. It is primarily used to demonstrate pathological or other physiological alterations of living tissues and is a commonly used form of medical imaging. MRI has also found many novel applications outside of the medical and biological fields such as rock permeability to hydrocarbons and certain non-destructive testing methods such as produce and timber quality characterisation. This new book presents the latest research in this field.

"Equine MRI" is a unique, comprehensive guide to MRI in the horse. Edited by Rachel Murray, a leading authority and researcher in the field with over ten years of equine clinical MRI experience, the book also includes contributions from worldwide experts in the subject.

Divided into the following four sections, the book presents key information based on previous validation work and clinical practice: Principles of MRI, including the practicalities of image acquisition and interpretationNormal MRI anatomy and normal variationsDifferent types of pathological changeOptions for clinical management and prognosis for different conditions

MRI is a rapidly expanding area in veterinary medicine that confers detailed, three-dimensional information on both bone and soft tissue. Expanding clinical knowledge, improvements in technology, and practical application of MRI to the standing and recumbent horse means this useful imaging modality has become an integral and essential part of the diagnostic evaluation in lameness and is a realistic option for investigation of ophthalmological, neurological and cranial pathology.

"Equine MRI" enables readers to understand the best ways to achieve good quality images, and provides a detailed explanation of the problems that may occur.

With close to 950 normal and abnormal images, this book offers considerable detail and examples of both common and uncommon problems, making it a great reference for equine veterinarians, veterinary students, specialists in equine surgery, and specialists in veterinary imaging.

Based on the 1st edition this 2nd edition volume provides a completely revised comprehensive overview of the current state of the development in magnetic resonance (MR) vascular imaging. The basic principles and technical features of MR angiography are outlined, consideration being given to both flow-dependent and flow-independent contrast-enhanced approaches. Specific chapters focus on image display techniques, blood flow quantification, hardware configurations, and the limitations and artifacts of MR angiography. The well-established approach of providing a clinical overview of MR angiography in different vascular areas has been continued, with the presentation of a large number of and representative MR angiograms based on current acquisition techniques. Suitable examination protocols for different vascular regions and lesions are described to facilitate correct application of the technique. Systematic comparison is made with other vascular imaging techniques.

Encyclopedia of NMR - Encompassing all relevant areas for NMR science and technology and applications in physics, chemistry and biology

This new 10 volume set captures every aspect of the interdisciplinary nature of magnetic resonance and provides the most complete and up-to-date source in the field. It includes many articles from the print editions of "Encyclopedia of Nuclear Magnetic Resonance "and recent "EMR Books," as well as new and updated articles published online in the "Encyclopedia of Magnetic Resonance."

Covering key developments such as:

- New techniques

- Protein structures

- Dynamics of molecular processes

- Characterization of materials, polymers and nano-materials

- NMR crystallography

- Solid biological samples such as membranes

Add Encyclopedia of NMR to your bookshelf for...

- Easy to access information - Covering all the techniques and applications in general NMR areas in an A-Z format

- Use as a learning tool - Revisit basics as well as get up-to-date with the latest methods and thinking

- Use in day-to-day work in the lab - Discover information on new techniques and applications, take advantage of useful hints and tips

- Short biographies of contributing authors - Showing the link between the career and the expertise of the contributing scientists

- Perspectives and personal recollections - A look back at major adventures, evolution and developments that have shaped the field, alongside leading researchers who share their personal involvements with NMR and MRI

Encyclopedia of NMR includes:

- Many original and updated articles from the print edition of "Encyclopedia of Nuclear Magnetic Resonance" (1996)

- Articles from "EMR Books" - special handbooks covering hot topic areas

- Additional NMR-focused articles published online in the "Encyclopedia ""of Magnetic Resonance" - the updating online resourceTake advantage of the introductory price: 2500 / 3220 / $3750, valid until 28th February 2013. Prices will revert to 3067 / 3940 / $4600 thereafter.

Subscribe to the updating online edition -" eMagRes"

Available online for libraries and institutions as "eMagRes" (formerly published as the "Encyclopedia of Magnetic Resonance)," the online edition relaunched in January 2013with a range of new features which makes the site more user-friendly and more attractive to both the medical MRI community and to the molecular chemistry, physics and biology communities.

This reference work first published online in 2007, and since that date has been updated four times a year with approximately 10% new or updated content each year across a wide range of topics. As part of the relaunch the content structure has been revised to aid quick navigation for both the medical MRI community and the molecular chemistry, physics and biology communities to articles of interest.

Find out more about the online edition here: www.wileyonlinelibrary.com/ref/eMagRes

This is the first textbook dedicated to CEST imaging and covers the fundamental principles of saturation transfer, key features of CEST agents that enable the production of imaging contrast, and practical aspects of preparing image-acquisition and post-processing schemes suited for in vivo applications. CEST is a powerful MRI contrast mechanism with unique features, and the rapid expansion it has seen over the past 15 years since its original discovery in 2000 has created a need for a graduate-level handbook describing all aspects of pre-clinical, translational, and clinical CEST imaging. The book provides an illustrated historical perspective by leaders at the five key sites who developed CEST imaging, from the initial saturation transfer NMR experiments performed in the 1960s in Stockholm, Sweden, described by Sture Forsen, to the work on integrating the basic principles of CEST into imaging by Robert Balaban, Dean Sherry, Silvio Aime, and Peter van Zijl in the United States and Italy. The editors, Drs. Michael T. McMahon, Assaf A. Gilad, Jeff W. M. Bulte, and Peter C. M. van Zijl, have been pioneers developing this field at the Johns Hopkins University School of Medicine and the Kennedy Krieger Institute including contributions to Nature Medicine, Nature Biotechnology, Nature Materials, and the Proceedings of the National Academy of Sciences. As recognition for their initial development of the field, Drs. van Zijl and Balaban were awarded the Laukien Prize in April 2016, established in 1999 to honor the memory of Professor Gunther Laukien, a co-founder of Bruker Biospin GmbH.

MR perfusion imaging is an area of major research interest and rapid clinical growth. Clinical Perfusion MRI: Techniques and Applications provides a concise and comprehensive review of the principles and applications of the field, covering dynamic susceptibility contrast, dynamic contrast enhancement, and arterial spin labeling imaging techniques. Principles of blood-volume and oxygenation imaging are included. The clinical applications of perfusion imaging in neurological disease and neuroscience are discussed - major topics including its use in imaging cerebrovascular disease and brain tumors and other neurological and neurodegenerative disorders. Non-neurologic applications are also covered with chapters on cardiac disease, breast cancer and other organ systems. Use of MR perfusion imaging in pediatrics is also discussed. Throughout the book case reports are included illustrating representative clinical examples. This book will be of interest to any clinician who uses MR perfusion imaging in their clinical practice, as well as researchers in the field of MRI.

The value of MR imaging for the evaluation of musculoskeletal system disorders cannot be over-stated. It is the only imaging modality that enables visualization of all components of the joints within single examinations. Yet, given the bewildering variety of possible sequence parameters, with and without contrast medium, acquiring and interpreting MR images with confidence is a challenge, requiring experience usually only gained after examining 1000s of studies with a careful systematic approach. Like the First Edition, the Second Edition of MRI of the Musculoskeletal System assists the radiologist in acquiring the most reliable and complete imaging information, so as to achieve a high degree of diagnostic certainty quickly and efficiently. Key Features: More than 2000 MR images of reference quality, the majority new for this edition Drawings, where helpful, aid the reader in identifying and delineating normal and pathological entities Includes all the latest advanced techniques: MR neurography and myelography, diffusion imaging, quantitative MRI, mDIXON, and more All MR exams described fully, with choice of sequence, positioning, choice of coils, when/how to use contrast, protocols Discussions of possible errors in interpretation Comparison of MR imaging with other modalities Tables expand and organize information on sequence parameters and differential diagnoses More than just an authoritative reference, Vahlensieck's MRI of the Musculoskeletal System is the ideal practical helper to accompany the radiologist at the workstation on a daily basis.

At the heart of every medical imaging technology is a sophisticated mathematical model of the measurement process and an algorithm to reconstruct an image from the measured data. This book provides a firm foundation in the mathematical tools used to model the measurements and derive the reconstruction algorithms used in most imaging modalities in current use. In the process, it also covers many important analytic concepts, and techniques used in Fourier analysis, integral equations, sampling theory, and noise analysis. This text uses X-ray computed tomography as a "pedagogical machine" to illustrate important ideas and incorporates extensive discussions of background material making the more advanced mathematical topics accessible to readers with a less formal mathematical education. The mathematical concepts are illuminated with over 200 illustrations and numerous exercises. New to the second edition are a chapter on magnetic resonance imaging (MRI), a revised section on the relationship between the continuum and discrete Fourier transforms, a new section on Grangreat's formula, an improved description of the gridding method, and a new section on noise analysis in MRI.

Through numerous examples, the principles of the relationship between chemical structure and the NMR spectrum are developed in a logical, step-by-step fashion * Includes examples and exercises based on real NMR data including full 600 MHz one- and two-dimensional datasets of sugars, peptides, steroids and natural products * Includes detailed solutions and explanations in the text for the numerous examples and problems and also provides large, very detailed and annotated sets of NMR data for use in understanding the material * Describes both simple aspects of solution-state NMR of small molecules as well as more complex topics not usually covered in NMR books such as complex splitting patterns, weak long-range couplings, spreadsheet analysis of strong coupling patterns and resonance structure analysis for prediction of chemical shifts * Advanced topics include all of the common two-dimensional experiments (COSY, ROESY, NOESY, TOCSY, HSQC, HMBC) covered strictly from the point of view of data interpretation, along with tips for parameter settings

Drug-resistant epilepsy with negative MRI is frequently seen in patients considered for epilepsy surgery; however, clinical evaluation and surgical treatment is very complex and challenging. Advanced imaging techniques are needed to detect the location of the epileptogenic zone. In most cases, intracranial EEG recording is required to delineate the region of seizure onset - this carries some risks of major complications. Moreover, the borders between the recorded seizure onset and the location of important brain functions are often indistinct in MRI-negative epilepsy. Overall, the outcome of MRI-negative surgery is less favorable than that of MRI-positive surgery, but it can significantly improve with optimal management. Each chapter critically appraises the role and value of specific diagnostic and treatment techniques to address the challenges of MRI-negative epilepsy surgery. Authors critique evidence and share their expertise on the diagnostic options and surgical approaches that make epilepsy surgery possible and worthwhile in patients with this condition.

The author of this book has been contributing to developments of an electron paramagnetic resonance (EPR) imaging system and its applications for more than 10 years. This system was designed for EPR measurements of experimental animals such as rats and mice, and its applications were mainly for biological researches. Thus, a lot of parameters to design an EPR imaging system are determined on the assumption that this system can be used for in vivo studies. The main aim of performing in vivo EPR measurements is to estimate in vivo reducing ability that cannot be obtained by other measuring methods at present. In this book, before main chapters about EPR imaging, this aim and specifications of apparatuses for achieving this aim are stated as a background. After description of instrumental components of an in vivo spectrometer, a theory, instruments, data processing, and applications of EPR imaging are explained. In the chapters about instruments and data processing, their details are described so that one can build the apparatus and obtain data. In the chapter about applications, examples of in vivo estimation of reducing ability in experimental models of some diseases are presented. In the last chapter, an explanation about region-selected intensity determination (RSID), a novel method that allows estimation of in vivo reducing ability at a selected anatomical region without complications of previous EPR imaging method, is stated.

This practical guide offers an accessible introduction to the principles of MRI physics. Each chapter explains the why and how behind MRI physics. Readers will understand how altering MRI parameters will have many different consequences for image quality and the speed in which images are generated. Practical topics, selected for their value to clinical practice, include progressive changes in key MRI parameters, imaging time, and signal to noise ratio. A wealth of high quality illustrations, complemented by concise text, enables readers to gain a thorough understanding of the subject without requiring prior in-depth knowledge.

As a practical reference guide for designing and performing experiments, this book focuses on the five most common classes of contrast agents for MRI namely gadolinium complexes, chemical exchange saturation transfer agents, iron oxide nanoparticles, manganese complexes and fluorine contrast agents. It describes how to characterize and evaluate them and for each class, a description of the theory behind their mechanisms is discussed briefly to orient the new reader. Detailed subchapters discuss the different physical chemistry methods used to characterize them in terms of their efficacy, safety and in vivo behavior. Important consideration is also given to the different physical properties that affect the performance of the contrast agents. The editors and contributors are at the forefront of research in the field of MRI contrast agents and this unique, cutting edge book is a timely addition to the literature in this area.

This book details the latest research on magnetic resonance (MRI) tagging technology related to heart mechanics. The book compare and contrast different tagging techniques, explain different imaging sequences and post processing algorithms, and associate the tagging techniques with different applications. It presents MRI techniques in chronological order, describing how the drawbacks of a certain technique led to the invention of the next one.

Based on research and clinical trials, this book details the latest research in magnetic resonance imaging (MRI) tagging technology related to heart mechanics. It covers clinical applications and examines future trends, providing a guide for future uses of MRI technology for studying heart mechanics.

Magnetic resonance imaging (MRI) is a technique used in biomedical imaging and radiology to visualize internal structures of the body. Because MRI provides excellent contrast between different soft tissues, the technique is especially useful for diagnostic imaging of the brain, muscles, and heart. In the past 20 years, MRI technology has improved significantly with the introduction of systems up to 7 Tesla (7 T) and with the development of numerous post-processing algorithms such as diffusion tensor imaging (DTI), functional MRI (fMRI), and spectroscopic imaging. From these developments, the diagnostic potentialities of MRI have improved impressively with an exceptional spatial resolution and the possibility of analyzing the morphology and function of several kinds of pathology. Given these exciting developments, the Magnetic Resonance Imaging Handbook is a timely addition to the growing body of literature in the field. Comprised of three volumes, this comprehensive handbook: Covers the technology and practice of MRI from physical principles to cutting-edge applications Discusses MRI of the neck, brain, cardiovascular system, thorax, abdomen, pelvis, and musculoskeletal system Highlights each organ's anatomy and pathological processes with high-quality images Examines the protocols and potentialities of advanced MRI scanners such as 7 T systems Includes extensive references at the end of each chapter to enhance further study Thus, the Magnetic Resonance Imaging Handbook provides radiologists and imaging specialists with a valuable, state-of-the-art reference on MRI.