Plant Polysaccharides as Pharmaceutical Excipients explores innovative techniques and applications of plant-derived polysaccharides as pharmaceutical excipients. Plant polysaccharides are sustainable, renewable and abundantly available, offering attractive properties in terms of water solubility, swelling ability, non-toxicity and biodegradability. These qualities have resulted in extensive exploration into their applications as excipients in a variety of pharmaceutical dosage forms. This book takes a comprehensive, application-oriented approach, drawing on the very latest research that includes sources, classification and extraction methods of plant polysaccharides. Subsequent chapters focus on plant polysaccharides for individual pharmaceutical applications, enabling the reader to understand their preparation for specific targeted uses. Throughout the book, information is supported by illustrations, chemical structures, flow charts and data tables, providing a clear understanding. Finally, future perspectives and challenges are reviewed and discussed.

Wearable Telemedicine Technology for the Healthcare Industry: Product Design and Development focuses on recent advances and benefits of wearable telemedicine techniques for remote health monitoring and prevention of chronic conditions, providing real time feedback and help with rehabilitation and biomedical applications. Readers will learn about various techniques used by software engineers, computer scientists and biomedical engineers to apply intelligent systems, artificial intelligence, machine learning, virtual reality and augmented reality to gather, transmit, analyze and deliver real-time clinical and biological data to clinicians, patients and researchers. Wearable telemedicine technology is currently establishing its place with large-scale impact in many healthcare sectors because information about patient health conditions can be gathered anytime and anywhere outside of traditional clinical settings, hence saving time, money and even lives.

Novel Platforms for Drug Delivery Applications covers diverse aspects in the design, synthesis and characterization of novel drug delivery platforms and devices. This book comprehensively details the development, application and performance of various novel molecular frameworks as potent drug delivery vehicles. Chapters cover a range of materials and molecular platforms for drug delivery, from hydrogels, nanocarriers and metal-organic-frameworks, to ?-cyclodextrin and polyphosphazene. Each chapter discusses the benefits and limitations of each drug delivery system, as well as toxicological and safety implications. This book offers an interdisciplinary approach to this fast-moving topic, bridging the disciplines of materials science and pharmacology.

Teen drug use is a critical and timely health issue that deeply affects adolescent development in a number of important areas, including social, cognitive, and affective functioning, as well as long-term health and wellbeing. Trends indicate that drug use is starting at an earlier age, the potency of several drugs is much stronger than in the past, and more new drugs are illegally being manufactured to provide faster, heightened effects. In addition, illegal use of prescription drugs and drug diversion or the sharing of prescription medication is also on the rise amongst teens. Parenting and Teen Drug Use provides comprehensive coverage of the most current research on youth drug use and prevention, carefully and meticulously presenting empirical evidence and theoretical arguments that underlie the mechanisms linking parental socialization and adolescent drug use. Written by leading experts, chapters examine the causes and consequences of drug use, the myriad ways to prevent it, and the latest findings from the prevention research community regarding what works, with a specific emphasis on parenting techniques that have shown the most promise for reducing or preventing drug use in teens. Parenting and Teen Drug Use will provide valuable insight to a wide audience of clinicians, treatment providers, school counselors, prevention experts, social workers, physicians, substance abuse counselors, students, and those who work with youth on a day-to-day basis to influence positive youth adaptation.

Mechanical Design of Piezoelectric Energy Harvesters: Generating Electricity from Human Walking provides the state-of-the-art, recent mechanical designs of piezoelectric energy harvesters based on piezoelectric stacks. The book discusses innovative mechanism designs for energy harvesting from multidimensional force excitation, such as human walking, which offers higher energy density. Coverage includes analytical modeling, optimal design, simulation study, prototype fabrication, and experimental investigation. Detailed examples of their analyses and implementations are provided. The book's authors provide a unique perspective on this field, primarily focusing on novel designs for PZT Energy harvesting in biomedical engineering as well as in integrated multi-stage force amplification frame. This book presents force-amplification compliant mechanism design and force direction-transmission mechanism design. It explores new mechanism design approaches using piezoelectric materials and permanent magnets. Readers can expect to learn how to design new mechanisms to realize multidimensional energy harvesting systems.

Applications of Unsaturated Polyester Resins: Synthesis, Modifications, and Preparation Methods takes a practical approach to unsaturated polyester-based materials and their preparation for implementation in a range of innovative areas. Sections introduce the background of polyester and the fundamentals of unsaturated polyester resins (UPRs), including chemistry, additives, curing, and processing methods. Hydrolytic stability and structure-property relationships are also discussed in detail, along with coverage of modification strategies for UPR and the development of bio-composites incorporating natural fiber with unsaturated polyester. Subsequent chapters focus on the preparation of UPR for specific target applications, including in construction, marine and aerospace, adhesives and coatings, insulation systems, electrics, pipeline corrosion, military, biomedicine, and tissue engineering. Finally, the advantages and disadvantages of UPR compared to other resins, in terms of properties and performance, as well as life cycle assessment, are addressed and analyzed.

3D Printing in Medicine, Second Edition examines the rapidly growing market of 3D-printed biomaterials and their clinical applications. With a particular focus on both commercial and premarket tools, the book looks at their applications within medicine and the future outlook for the field. The chapters are written by field experts actively engaged in educational and research activities at the top universities in the world. The earlier chapters cover the fundamentals of 3D printing, including topics such as materials and hardware. The later chapters go on to cover innovative applications within medicine such as computational analysis of 3D printed constructs, personalized 3D printing - including 3D cell and organ printing and the role of AI - with a subsequent look at the applications of high-resolution printing, 3D printing in diagnostics, drug development, 4D printing, and much more. This updated new edition features completely revised content, with additional new chapters covering organs-on-chips, bioprinting regulations and standards, intellectual properties, and socio-ethical implications of organs-on-demand.

Modern Practical Healthcare Issues in Biomedical Instrumentation describes the designs, applications and principles of several medical devices used in hospitals and at home. The book presents practical devices that can potentially be used for healthcare purposes. Sections cover the use of biosensors to monitor the physiological properties of the human body, focusing on devices used to evaluate, measure and manipulate the biological system, and highlighting practical devices that can potentially be used for healthcare purposes. It is an excellent resource for undergraduate, graduate and post-graduate students of biomedical engineering.

Brain Seizure Detection and Classification Using Electroencephalographic Signals presents EEG signal processing and analysis with high performance feature extraction. The book covers the feature selection method based on One-way ANOVA, along with high performance machine learning classifiers for the classification of EEG signals in normal and epileptic EEG signals. In addition, the authors also present new methods of feature extraction, including Singular Spectrum-Empirical Wavelet Transform (SSEWT) for improved classification of seizures in significant seizure-types, specifically epileptic and Non-Epileptic Seizures (NES). The performance of the system is compared with existing methods of feature extraction using Wavelet Transform (WT) and Empirical Wavelet Transform (EWT). The book's objective is to analyze the EEG signals to observe abnormalities of brain activities called epileptic seizure. Seizure is a neurological disorder in which too many neurons are excited at the same time and are triggered by brain injury or by chemical imbalance.

Leveraging Artificial Intelligence in Global Epidemics provides readers with a detailed technical description of the role Artificial Intelligence plays in various stages of a disease outbreak, using COVID-19 as a case study. In the fight against epidemics, medical staff are on the front line; but behind the lines the battle is fought by researchers, and data scientists. Artificial Intelligence has been helping researchers with computer modeling and simulation for predictions about disease progression, the overall economic situation, tax incomes and population development. In the same manner, AI can prepare researchers for any emergency situation by backing the medical science. Artificial Intelligence plays a key and cutting-edge role in the preparedness for and dealing with the outbreak of global epidemics. It can help researchers analyze global data about known viruses to predict the patterns of the next pandemic and the impacts it will have. Not only prediction, AI plays an increasingly important role in assessing readiness, early detection, identification of patients, generating recommendations, situation awareness and more. It is up to the right input and the innovative ways by humans to leverage what AI can do. As COVID-19 has grabbed the world and its economy today, an analysis of the COVID-19 outbreak and the global responses and analytics will pay a long way in preparing humanity for such future situations.

Foot and Ankle Biomechanics is a one source, comprehensive and modern reference regarding foot and ankle biomechanics. This text serves as both a master reference for foot biomechanics, presenting a clear state of the research and capabilities in the field. The customers for this book will be those looking for information on foot and ankle biomechanics for a range of applications; for example, designers of orthotics.

Advances in Biomedical Polymers and Composites: Materials and Applications is a comprehensive guide to polymers and polymer composites for biomedical applications, bringing together detailed information on their preparation, properties, cutting-edge technologies, innovative materials and key application areas. Sections introduce polymers and composites in biomedical applications and cover characterization techniques, preparation and properties of composites and gel-based systems. Innovative technologies and instruments used in the fabrication of polymer composites for biomedical applications are then presented in detail, including 3D bioprinting, 4D printing, electrospinning, stimuli-responsive polymers and quantum dots. This is a valuable resource for anyone looking to gain a broader understanding of polymers and composites for biomedical applications. In addition, it is ideal for readers who want to conduct interdisciplinary research or explore new avenues for research and development.

Neural Engineering for Autism Spectrum Disorder, Volume One: Imaging and Signal Analysis Techniques presents the latest advances in neural engineering and biomedical engineering as applied to the clinical diagnosis and treatment of Autism Spectrum Disorder (ASD). Advances in the role of neuroimaging, infrared spectroscopy, sMRI, fMRI, DTI, social behaviors and suitable data analytics useful for clinical diagnosis and research applications for Autism Spectrum Disorder are covered, including relevant case studies. The application of brain signal evaluation, EEG analytics, feature selection, and analysis of blood oxygen level-dependent (BOLD) signals are presented for detection and estimation of the degree of ASD.

Nanostructured Materials for Tissue Engineering introduces the key properties and approaches involved in using nanostructured materials in tissue engineering, including functionalization, nanotechnology-based regenerative techniques, toxicological and biocompatible aspects. A broad range of nanomaterial types are covered, from polymer scaffolds and nanocomposites to gold nanoparticles and quantum dots. This book aids the reader in materials selection, as well as matching to the best applications, including bone, skin, pulmonary or neurological tissue engineering. Users will find this book to be an up-to-date review on this fast-changing field that is ideal for materials scientists, tissue engineers, biomedical engineers, and pharmaceutical scientists.

Polymeric Micelles for Drug Delivery provides a comprehensive overview on the synthesis, characterization and application of polymeric micelles in drug delivery applications. The use of nanomedicines and carriers, such as polymeric micelles, has made it possible to deliver drugs, genes and therapeutic agents to localized disease sites to maximize clinical benefit while limiting unwanted side effects. This book thoroughly reviews the development and application of polymeric micelles for drug delivery, covering various polymer types and the synthesis, characterization and pharmacokinetics of different micelles. Subsequent chapters go on to look at the range of drug delivery applications of polymeric micelles - such as mucosal and transdermal - and the assorted stimuli-responsive micelles available. The book concludes with an important analysis of the environmental and regulatory aspects associated with micelle development and clinical translation.

Principles of Biomaterials Encapsulation: Volume One, provides an expansive and in-depth resource covering the key principles, biomaterials, strategies and techniques for encapsulation. Volume One begins with an introduction to encapsulation, with subsequent chapters dedicated to a broad range of encapsulation principles and techniques, including spray chilling and cooling, microemulsion, polymerization, extrusion, cell microencapsulation and much more. This book methodically details each technique, assessing the advantages and disadvantages of each, allowing the reader to make an informed decision when using encapsulation in their research. Principles of Biomaterials Encapsulation: Volume One enables readers to learn about the various strategies and techniques available for encapsulation of a wide selection of biomedical substrates, such as drugs, cells, hormones, growth factors and so on. Written and edited by well-versed materials scientists with extensive clinical, biomedical and regenerative medicine experience, this book offers a deeply interdisciplinary look at encapsulation in translational medicine. As such, this book will provide a useful resource to a broad readership, including those working in the fields of materials science, biomedical engineering, regenerative and translational medicine, pharmacology, chemical engineering and nutritional science.

AI Assurance: Towards Trustworthy, Explainable, Safe, and Ethical AI provides readers with solutions and a foundational understanding of the methods that can be applied to test AI systems and provide assurance. Anyone developing software systems with intelligence, building learning algorithms, or deploying AI to a domain-specific problem (such as allocating cyber breaches, analyzing causation at a smart farm, reducing readmissions at a hospital, ensuring soldiers' safety in the battlefield, or predicting exports of one country to another) will benefit from the methods presented in this book. As AI assurance is now a major piece in AI and engineering research, this book will serve as a guide for researchers, scientists and students in their studies and experimentation. Moreover, as AI is being increasingly discussed and utilized at government and policymaking venues, the assurance of AI systems-as presented in this book-is at the nexus of such debates.

Evidence-Based Validation of Herbal Medicines: Translational Research on Botanicals brings together current thinking and practice in the characterization and validation of natural products. The book describes different approaches and techniques for evaluating the quality, safety and efficacy of herbal medicine, particularly methods to assess their activity and understand compounds responsible and their probable underlying mechanisms of action. This book brings together the views, expertise and experiences of scientific experts in the field of medicinal plant research, hence it will be useful for researcher who want to know more about the natural lead with their validation and also useful to exploit traditional medicines.

New Trends in Smart Nanostructured Biomaterials in Health Sciences provides guidance on the design and synthesis of nanostructured smart biomaterials, as well as the resultant therapeutic effects and associated biomedical applications of these novel materials. The book provides readers with a deeper understanding of these novel biomaterials and aids them in making informed decisions when selecting appropriate materials for tissue engineering and cancer therapy applications. It will be of specific interest to materials scientists, biomedical engineers, oncological scientists, tissue engineers and those working in regenerative medicine. Nanostructured smart materials have the special ability to respond to changes in the cell microenvironment, allowing for robust, biocompatible and rapidly adaptable, therapeutic and restorative action against a range of ailments. These materials are thus ideal candidates for use in tissue engineering and cancer therapy due to the varying nature of the cell microenvironment between persons, tissues and cancers. This book covers the design, synthesis, unique properties and application of smart biomaterials in these two key topic areas of tissue engineering and cancer therapeutics.

Protein-Based Biopolymers: From Source to Biomedical Applications provides an overview on the development and application of protein biopolymers in biomedicine. Protein polymers have garnered increasing focus in the development of biomedical materials, devices and therapeutics due to their intrinsic bioactivity, biocompatibility and biodegradability. This book comprehensively reviews the latest advances on the synthesis, characterization, properties and applications of protein-based biopolymers. Each chapter is dedicated to a single protein class, covering a broad range of proteins including silk, collagen, keratin, fibrin, and more. In addition, the book explores the biomedical potential of these polymers, from tissue engineering, to drug delivery and wound healing. This book offers a valuable resource for academics and researchers in the fields of materials science, biomedical engineering and R&D groups working in pharmaceutical and biomedical industries.