Edited by two leading orthopedic surgeons who are specialists in the treatment of hemophilia, Orthopedic Surgery in Patients with Hemophilia shows all the surgical techniques needed for surgical treatment of musculoskeletal complications of hemophilia. A practical guide, designed for use on the ward or in the office, this book draws on the experience of numerous specialists worldwide, from developed and developing countries. As well as orthopedic surgery, it also covers research, hematology, and rehabilitation. Although of primary interest to the orthopedic surgeon, rheumatologist, and physiotherapist, this book will also be relevant to the hematologist responsible for the care of the hemophiliac patient. Written for: Orthopedic surgeons, hematologists, physiotherapists, rheumatologists

Newly revised and updated, this book provides geriatricians and orthopedic surgeons with the most vital tools to treat elderly patients who sustain a variety of fractures. The text uniquely encompass the etiologies of fracture in the elderly, perioperative management, the surgical treatment of common fractures in the elderly, as well as rehabilitation and prevention in the older patient. It focuses on the most current data and opinions regarding assessment and management of geriatric conditions that predispose the elderly to fracture, perioperative complications and subsequent functional decline. Unlike any other text, experts in both orthopedics and geriatrics review the content of each chapter for readability and appeal to his/her respective discipline, making this the physician's ultimate guide to treating elderly patients with injuries. Fractures in the Elderly, Second Edition is a valuable resource for geriatricians, orthopedic surgeons, physiologists, and rehabilitation specialists.

Describes the genesis, pathology, clinical features, presentation, syndromes, clinical examination, investigation procedures, treatment, prophylaxis, and surgery of common vertebral joint problems.New edition of a highly successful, widely acclaimed book Completely updated to take account of recent developments in research and practice The Gray's Anatomy" of spinal musculoskeletal pain - now the essential reference for all involved in the treatment of vertebral conditions The only single book to offer a comprehensive survey of the whole field Covers the genesis, pathology, clinical features, presentation, syndromes, clinical examination, investigation procedures, treatment, prophylaxis, and surgery of common vertebral joint problems Gives the reader a thoughtful and critical digest of more than 2500 references - two-thirds of theseSuperbly illustrated: 412 photographs and 206 line illustrations"

This book is a comprehensive guide to orthopaedics for postgraduate medical students. The fifth edition has been fully revised to present the latest developments and understanding in the field. The book covers numerous injuries and disorders, with each topic beginning with an overview of relevant anatomy, followed by principles and methods of diagnosis and clinical and surgical management. Each chapter includes a brief summary outlining key points, as well as example X-Rays for the topic in discussion. The fifth edition features new sections on trauma, geriatric orthopaedics, arthroscopy, and surgical techniques, as well as additional images including new X-Rays and MRI scans, and line diagrams. Key Points Comprehensive guide to orthopaedics for postgraduate medical students Fully revised, fifth edition with new topics More than 1300 clinical images and diagrams, many new to this edition Previous edition (9788184487442) published in 2010

Histotechnology and histomorphometry are the major methodologies in bone and cartila- related research. Handbook of Histology Methods for Bone and Cartilage is an outgrowth of the editors' own quest for information on bone and cartilage histology and histomorphometry. It is designed to be an experimental guide for personnel who work in the areas of basic and clinical bone and cartilage, orthopedic, or dental research. It is the first inclusive and organized reference book on histological and histomorphometrical techniques on bone and cartilage specimens. The topic has not previously been covered adequately by any existing books in the field. Handbook of Histology Methods for Bone and Cartilage has six major parts and is designed to be concise as well as inclusive, and more practical than theoretical. The text is simple and straightforward. Large numbers of tables, line drawings, and micro- or macro-photographs, are used to help readers better understand the content. Full bibliographies at the end of each chapter guide readers to more detailed information. A book of this length cannot discuss every method for bone and cartilage histology that has been used over the years, but it is hoped that major methods and their applications have been included.

Modern society is altering the lifestyle and longevity of its members much more quickly than evolutionary adaptation to these changes can take place. The problem of calcium deficiency in the population is compounded by the growing percentage of aged individuals with relatively fragile, less massive skeletons. Current-day civilizations are much more effective in prolonging human life in a state of relative debility than even a few decades ago. This reality is unlikely to change and mandates that we develop strategies to prevent aging-related diseases like osteoporosis before they become manifest. Osteoporosis: Genetics, Prevention and Treatment places emphasis on the (1) genetic predisposition, (2) early recognition and (3) prevention of osteoporosis. The intent is not to move the practitioner's attention away from intervention therapy of osteoporosis, but rather to expand their view of this disease as one beginning at birth and one in which susceptibility is manifest at the conclusion of adolescence, not at menopause. The book concludes with an informed view of the future in terms of the recognition, prevention and management of osteoporosis.

Physical Therapy – Treatment of Common Orthopedic Conditions is a highly illustrated, evidence-based guide to the treatment of a range of common orthopaedic disorders, edited by US based experts in the field. Divided into sixteen chapters, across three sections, the book begins with a section on upper extremity, including conditions such as thoracic outlet syndrome, rotator cuff impingement, and carpal tunnel syndrome. The second section covers the spine, including sprains and strains, and cervical radiculopathy. The final section focuses on lower extremity, covering conditions such as hamstring strain, tendinopathy, and medial tibial stress syndrome. Each chapter begins with an overview of important information for diagnosis, followed by detailed evaluation and treatment approaches, which include conservative therapy, as well as complimentary, alternative, medical and surgical interventions. The text is enhanced by 850 full colour images and illustrations. Physical Therapy – Treatment of Common Orthopedic Conditions references more than 1700 journal articles and books, ensuring authoritative content throughout this valuable resource for physiotherapists. Key Points Evidence-based guide to the treatment of a range of common orthopaedic conditions USA-based, expert editorial team References from over 1700 authoritative journal articles and books 850 full colour images and illustrations

This book represents the proceedings from a conference that took place in Dallas in the spring of 1999 which was entitled "Pediatric Gender Assignment - A Critical Reappraisal." Some participants rightfully argued that the conference really focused on the issue of pediatric gender assignment, and that reassignment was not applied in most cases. Their comments were reflected in the title of this monograph. This multidisciplinary meeting was sponsored by a conference grant from the National Institutes of Health, and a broad inquiry into this complex topic took place from many points of view. Basic scientists offered insight into mechanisms of sexual differentiation of the gonads, physical phenotype and imprinting of the central nervous system. Endocrinologists reviewed their experience in diagnosis and management, surgeons described traditional as well as innovative approaches, and there was strong representation from the ethical and behavioral sciences. In putting together such a panel, it was essential that we identify a cast of speakers who could address their viewpoints with strong convictions, and yet not let their passions render the meeting counter productive. We were not disappointed. While many differing points of view were firmly expressed by the panelists and audience, all viewpoints were accorded the respect they deserved. The concept behind the meeting and this book really originated in 1997 shortly after Diamond and Sigmundson published their long term follow up study of the John/Joan case.

A comprehensive description of macroscopic, microscopic, and radiological methods for the diagnosis of bone diseases. The book presents all the procedures involved in diagnosis, using not only radiological and histological techniques, but also modern immunohistochemical and scintigraphic methods. Succinct and well-structured therapeutic recommendations are provided for an array of bone diseases, making this a practice-oriented reference work for pathologists, radiologists, rheumatologists, and orthopedists.

The scope and importance of hip fractures is almost incomprehensible. With a world wide incidence of close to 2 million cases per year, these fractures pose a daunting challenge to our ability to affect and treat this epidemic. The incidence of these fractures is predicted to grow to 6 million in 2050 including a near term baby boom spike. Add the hospital mortality rate of up to 4% and the one mortality of from 8% to 20% and the life ending effect of these fractures becomes a glaring reality. Of those who initially survive their fracture, about 50% never walk the same again. The social problem in the care of these elderly people is enormous. Of course, any real solution to this problem will include education, prevention, surgical and hospital treatment protocols, long term rehabilitative efforts, social - justments and a generous contribution of money. This publication is primarily directed to the amplification of a new treatment modality that addresses only a fraction of the problem. It is, however, a quantum leap in the evolution of fixation with compression hip screws which are still the gold standard for surgical stabilization of pertrochanteric hip fractures. The Dynamic Martin Screw (DMS) addresses the issue of adjustability of the fixation angle with appropriate mechanical strength characteristics that were la- ing in its historical predecessors.

The second congress of the Paci?c Asian Society of Minimally Invasive Spine Surgery (PASMISS) held in Phuket,Thailand,August 5-6,2002,was highly s- cessful. Dr.Akira Dezawa, the president, had worked hard in organizing the congress,which was well attended.All scienti?c papers presented were of the highest standard and were worthy of publication in book form.This scienti?c meeting brought to light the practice of this modern surgical technique as it is being performed by spine surgeons in the Asia-Paci?c region.Dr.Dezawa has made a great effort to collect the papers from the congress,and to have them edited and published as a text that covers all aspects of the minimally invasive spine surgical approach. Minimally invasive spinal surgery will be a highlight of operative approaches in the twenty-?rst century and already has been popularized worldwide.This procedure will provide surgical options that address several pathological conditions in the spinal column without producing the types of morbidity commonly seen in open surgical procedures. The contents of this book provide highly relevant and detailed information. I certainly believe that it will be a great bene?t to all orthopedic surgeons who are interested in performing minimally invasive spine surgery. Charoen Chotigavanich,M.D. Chairman,Spinal Section The Royal College of Orthopedic Surgeons of Thailand V Preface Recent decades have been characterized by revolutionary changes in spinal surgery. Concurrent progress in implant technology and functional en- scopes and the improvement of less invasive surgical techniques has opened a new dimension for spine surgery.

Osteoarthritis (OA), the most common form of arthritis, is generally characterized by a slowly progressive degeneration of articular cartilage, particularly in the weight-bearing joints. It has a stronger prevalence in women, and its incidence increases with age. OA is a major and growing health concern in developed countries, owing to steadily increasing life expectancy and the demand for better quality of life. Because of its chronic nature and nonfatal outcome, OA affects the growing population of the elderly over an increasing time span. Moreover, despite its relatively benign character, OA is one of the most disabling diseases; it is responsible for increasing financial and social burdens in terms of medical treatments, forced inactivity, loss of mobility, and dependence. Despite a growing awareness of OA as a medical problem that has yet to reach its maximum impact on society, there is a surprising absence of effective medical treatments beyond pain control and surgery. So far, only symptom-modifying drugs are available, while there remains a major demand for disease-modifying treatments of proven clinical efficacy. This demand will hopefully be met in the future by some of the drugs that have been pressed into development and are now at different stages of clinical investigation. Nevertheless, the current lack of effective treatments reflects a still insufficient knowledge of cartilage with respect to its metabolism, interactions with other joint tissues, and causes and mechanisms (possibly of very different nature) leading to failure of its turnover.

Leading basic and clinical investigators from around the world summarize the most recent research on the molecular and cellular origins of lupus. Their cutting-edge articles review the mechanisms underlying abnormal immunity and introduce the powerful new concept that a disorder of multiple genes underlies the abnormal immune response, leading directly to the development of lupus. This pathophysiology is shown to involve a wide variety of cell types, including T cells, B cells, natural killer cells, macrophages/monocytes, and endothelial cells. Over time, the resulting long-term inflammation causes irreversible cell destruction and, ultimately, organ failure. Lupus: Molecular and Cellular Pathogenesis is a masterful new synthesis of all the new knowledge emerging today about lupus. Its new perspectives will sharpen the focus of research and ultimately lead to better and more effective treatment.

This collection of articles by leading orthopedic and craniofacial surgeons and researchers comprehensively reviews the biology of bone formation and repair, the basic science of autologous bone graft, allograft, bone substitutes, and growth factors, and explore their clinical application in patients with bone repair problems.

FRCS(Tr & Orth): MCQs and Clinical Cases offers a comprehensive set of over 120 practice questions and answers for trainees preparing for the FRCS Trauma & Orthopaedics exam. Chapters provide material in both the Single Best Answer (SBA) and Viva formats used in the exam. Featuring a wealth of practice questions and fully descriptive answers containing explanatory tables and references, this book is an essential revision tool designed to maximise chances of exam success. Content derived from the well-known "Exam Corner" section of the leading international journal The Bone & Joint Journal (formerly known as JBJS British volume), conveniently published together in one place for the first time Viva questions - Adult Pathology, Trauma, Hands, Children's Orthopaedics, Basic Science - enable candidates to focus on areas of weakness In-depth answers, with illustrations, help consolidate knowledge and understand key concepts

Advances in Materials Science and Implant Orthopedic Surgery brings together experts from major university hospitals, materials scientists specializing in bio-materials, and development engineers working for implant manufacturers to address such issues as: mechanisms of fixation; foreign-body immune response; generation and consequences of ionic and wear debris; materials selection, design and manufacturing schemes; and surgical techniques to maximize the safety and efficacy of the devices.

Rheumatoid arthritis (RA) is the most common and most severe form of inflammatory arthritis. The pathogenesis of RA has been the subject of intense research for several decades. The prevailing hypotheses have changed over the years, and have attempted to incorporate the most recent data. Although T cells represent an important component of the cells which infiltrate the joint synovium, their contribution at a late stage of the disease remains a matter of debate. The goal of this book is to outline the major arguments and data suggesting that T cells may, or may not, be central players in the pathogenesis of chronic RA. While each of the editors and authors has his/her own bias (as will be clear by reading the respective chapters), our hope is that the readers will enjoy a complete and balanced view of the critical questions and experiments. This is not just an intellectual exercise since the direction of future therapeutic interventions depends heavily on how one interprets the pathogenesis of RA and the contribution of T cells.