The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.

This book highlights numerical models as powerful tools for the optimal design of Micro-Electro-Mechanical Systems (MEMS). Most MEMS experts have a background in electronics, where circuit models or behavioral models (i.e. lumped-parameter models) of devices are preferred to field models. This is certainly convenient in terms of preliminary design, e.g. in the prototyping stage. However, design optimization should also take into account fine-sizing effects on device behavior and therefore be based on distributed-parameter models, such as finite-element models. The book shows how the combination of automated optimal design and field-based models can produce powerful design toolboxes for MEMS. It especially focuses on illustrating theoretical concepts with practical examples, fostering comprehension through a problem-solving approach. By comparing the results obtained using different methods, readers will learn to identify their respective strengths and weaknesses. In addition, special emphasis is given to evolutionary computing and nature-inspired optimization strategies, the effectiveness of which has already been amply demonstrated. Given its scope, the book provides PhD students, researchers and professionals in the area of computer-aided analysis with a comprehensive, yet concise and practice-oriented guide to MEMS design and optimization. To benefit most from the book, readers should have a basic grasp of electromagnetism, vector analysis and numerical methods.

This book includes selected, peer-reviewed contributions from the 2018 International Conference on "Physics and Mechanics of New Materials and Their Applications", PHENMA 2018, held in Busan, South Korea, 9-11 August 2018. Focusing on manufacturing techniques, physics, mechanics, and applications of modern materials with special properties, it covers a broad spectrum of nanomaterials and structures, ferroelectrics and ferromagnetics, and other advanced materials and composites. The authors discuss approaches and methods in nanotechnology; newly developed, environmentally friendly piezoelectric techniques; and physical and mechanical studies of the microstructural and other properties of materials. Further, the book presents a range of original theoretical, experimental and computational methods and their application in the solution of various technological, mechanical and physical problems. Moreover, it highlights modern devices demonstrating high accuracy, longevity and the ability to operate over wide temperature and pressure ranges or in aggressive media. The developed devices show improved characteristics due to the use of advanced materials and composites, opening new horizons in the investigation of a variety of physical and mechanical processes and phenomena.

Without sensors most electronic applications would not exist-sensors perform a vital function, namely providing an interface to the real world. Hall effect sensors, based on a magnetic phenomena, are one of the most commonly used sensing technologies today. In the 1970s it became possible to build Hall effect sensors on integrated circuits with onboard signal processing circuitry, vastly reducing the cost and enabling widespread practical use. One of the first major applications was in computer keyboards, replacing mechanical contacts. Hundreds of millions of these devices are now manufactured each year for use in a great variety of applications, including automobiles, computers, industrial control systems, cell phones, and many others.
The importance of these sensors, however, contrasts with the limited information available. Many recent advances in miniaturization, smart sensor configurations, and networkable sensor technology have led to design changes and a need for reliable information. Most of the technical information on Hall effect sensors is supplied by sensor manufacturers and is slanted toward a particular product line. System design and control engineers need an independent, readable source of practical design information and technical details that is not product- or manufacturer-specific and that shows how Hall effect sensors work, how to interface to them, and how to apply them in a variety of uses. This book covers:
-the physics behind Hall effect sensors
-Hall effect transducers
-transducer interfacing
-integrated Hall effect sensors and how to interface to them
-sensing techniques using Hall effect sensors
-application-specific sensorICs
-relevant development and design tools
This second edition is expanded and updated to reflect the latest advances in Hall effect devices and applications!
Information about various sensor technologies is scarce, scattered and hard to locate. Most of it is either too theoretical for working engineers, or is manufacturer literature that can't be entirely trusted. Engineers and engineering managers need a comprehensive, up-to-date, and accurate reference to use when scoping out their designs incorporating Hall effect sensors.
* A comprehensive, up-to-date reference to use when crafting all kinds of designs with Hall effect sensors
*Replaces other information about sensors that is too theoretical, too biased toward one particular manufacturer, or too difficult to locate
*Highly respected and influential author in the burgeoning sensors community

This thesis demonstrates a technology that enables pipetting-free high-throughput screening (HTS) on a miniaturized platform, eliminating the need for thousands of one-by-one pipetting and conventional liquid handling systems. This platform enhances accessibility to HTS and enables HTS to be used in small-to-medium scale laboratories. In addition, it allows large-scale combinatorial screening with a small number of valuable cells, such as patients' primary cancer cells. This technique will have a high impact for widespread use of HTS in the era of personalized medicine. In this thesis, the author firstly describes the need and concept of 'partipetting' for pipetting-free HTS platform. It is realized by the one-step pipetting and self-assembly of encoded drug-laden microparticles (DLPs) on the microwells. Next, the technical implementations required for the platform demonstration are described. It includes preparation of encoded DLPs, plastic chip fabrication, and realization of automated system. Lastly, screening of sequential drug combinations using this platform is demonstrated. This shows the potential of the proposed technology for various applications.

This book highlights recent advances in thin-film photonics, particularly as building blocks of metamaterials and metasurfaces. Recent advances in nanophotonics has demonstrated remarkable control over the electromagnetic field by tailoring the optical properties of materials at the subwavelength scale which results in the emergence of metamaterials and metasurfaces. However, most of the proposed platforms require intense lithography which makes them of minor practical relevance. Stacked ultrathin-films of dielectrics, semi-conductors, and metals are introduced as an alternative platform that perform unique or similar functionalities. This book discusses the new era of thin film photonics and its potential applications in perfect and selective light absorption, structural coloring, biosensing, enhanced spontaneous emission, reconfigurable photonic devices and super lensing.

This book compiles the fundamentals, applications and viable product strategies of biomimetic lipid membranes into a single, comprehensive source. It broadens its perspective to interdisciplinary realms incorporating medicine, biology, physics, chemistry, materials science, as well as engineering and pharmacy at large. The book guides readers from membrane structure and models to biophysical chemistry and functionalization of membrane surfaces. It then takes the reader through a myriad of surface-sensitive techniques before delving into cutting-edge applications that could help inspire new research directions. With more than half the world's drugs and various toxins targeting these crucial structures, the book addresses a topic of major importance in the field of medicine, particularly biosensor design, diagnostic tool development, vaccine formulation, micro/nano-array systems, and drug screening/development. Provides fundamental knowledge on biomimetic lipid membranes; Addresses some of biomimetic membrane types, preparation methods, properties and characterization techniques; Explains state-of-art technological developments that incorporate microfluidic systems, array technologies, lab-on-a-chip-tools, biosensing, and bioprinting techniques; Describes the integration of biomimetic membranes with current top-notch tools and platforms; Examines applications in medicine, pharmaceutical industry, and environmental monitoring.

This book covers the recent developments in the production of micro and nano size products, which cater to the needs of the industry. The processes to produce the miniature sized products with unique characteristics are addressed. Moreover, their application in areas such as micro-engines, micro-heat exchangers, micro-pumps, micro-channels, printing heads and medical implants are also highlighted. The book presents such microsystem-based products as important contributors to a sustainable economy. The recent research in this book focuses on the development of new micro and nano manufacturing platforms while integrating the different technologies to manufacture the micro and nano components in a high throughput and cost effective manner. The chapters contain original theoretical and applied research in the areas of micro- and nano-manufacturing that are related to process innovation, accuracy, and precision, throughput enhancement, material utilization, compact equipment development, environmental and life-cycle analysis, and predictive modeling of manufacturing processes with feature sizes less than one hundred micrometers.

Plant Nanobionics, Volume 2 continues the important discussion of nanotechnology in plants, but focuses with a focus on biosynthesis and toxicity. This book discusses novel approaches to biosynthesis of nanoparticles for the increase of plant production systems, controlled release of agrochemicals and management of plant biotic stress. Green biosynthesis of metallic nanoparticles from bee propolis, artificial photosynthesis and hybrid structures are presented. Although engineered nanoparticles have great potential for solving many agricultural and societal problems, their consequences on the ecosystems and environment must be responsibly considered. This volume aims to contribute to the limited literature on this topic through its comprehensive examination of nanoparticle toxicity on plants, microbes and human health. Environmental risks with recent data are discussed as well as risks associated with the transfer of nanoparticles through the food chain. This volume highlights the study of a mechanistic approach and the study of nanoparticles towards nanobionics. The application of polymeric materials for smart packing in the food industry and agriculture sector as well as the future of nanomaterials in detecting soil microbes for environmental remediation are also included.

This critical volume provides an in-depth presentation of copper wire bonding technologies, processes and equipment, along with the economic benefits and risks. Due to the increasing cost of materials used to make electronic components, the electronics industry has been rapidly moving from high cost gold to significantly lower cost copper as a wire bonding material. However, copper wire bonding has several process and reliability concerns due to its material properties. Copper Wire Bonding book lays out the challenges involved in replacing gold with copper as a wire bond material, and includes the bonding process changes-bond force, electric flame off, current and ultrasonic energy optimization, and bonding tools and equipment changes for first and second bond formation. In addition, the bond-pad metallurgies and the use of bare and palladium-coated copper wires on aluminum are presented, and gold, nickel and palladium surface finishes are discussed. The book also discusses best practices and recommendations on the bond process, bond-pad metallurgies, and appropriate reliability tests for copper wire-bonded electronic components. In summary, this book: Introduces copper wire bonding technologies Presents copper wire bonding processes Discusses copper wire bonding metallurgies Covers recent advancements in copper wire bonding including the bonding process, equipment changes, bond-pad materials and surface finishes Covers the reliability tests and concerns Covers the current implementation of copper wire bonding in the electronics industry Features 120 figures and tables Copper Wire Bonding is an essential reference for industry professionals seeking detailed information on all facets of copper wire bonding technology.

The volume includes 30 contributions from the 3rd International Workshop on Advanced Dynamics and Model Based Control of Structures and Machines representing the frontiers in the mechanics of controlled machines and structures. The Workshop, held in Perm, Russia in September 2017 continued a series of international workshops, starting in with the Japan - Austria Joint Workshop on Mechanics and Model Based Control of Smart Materials and Structures, the Russia - Austria Joint Workshop on Advanced Dynamics and Model Based Control of Structures and Machines and the first two editions of the International Workshop on Advanced Dynamics and Model Based Control of Structures and Machines. The previous workshops took place in Linz, Austria in September 2008 and April 2010, in St. Petersburg, Russia in July 2012 and in Vienna, Austria in September 2015. The up-to-date contributions are authored by internationally re-known leading experts in dynamics and control representing a broad spectrum of topics in the field of Advanced Structures and Machines; both, with respect to theoretical aspects as well as applications to contemporary engineering problems.

This book provides essential insights into designing a localized DNA circuit to promote the rate of desired hybridization reactions over undesired leak reactions in the bulk solution. The area of dynamic DNA nanotechnology, or DNA circuits, holds great promise as a highly programmable toolbox that can be used in various applications, including molecular computing and biomolecular detection. However, a key bottleneck is the recurring issue of circuit leakage. The assembly of the localized circuit is dynamically driven by the recognition of biomolecules - a different approach from most methods, which are based on a static DNA origami assembly. The design guidelines for individual reaction modules presented here, which focus on minimizing circuit leakage, are established through NUPACK simulation and tested experimentally - which will be useful for researchers interested in adapting the concepts for other contexts. In the closing section, the design concepts are successfully applied to the biomolecular sensing of a broad range of targets including the single nucleotide mutations, proteins, and cell surface receptors.

This book focuses on novel bismuth-containing alloys and nanostructures, covering a wide range of materials from semiconductors, topological insulators, silica optical fibers and to multiferroic materials. It provides a timely overview of bismuth alloys and nanostructures, from material synthesis and physical properties to device applications and also includes the latest research findings. Bismuth is considered to be a sustainable and environmentally friendly element, and has received increasing attention in a variety of innovative research areas in recent years. The book is intended as a reference resource and textbook for graduate students and researchers working in these fields.

Starting from a broad overview of heat transport based on the Boltzmann Transport Equation, this book presents a comprehensive analysis of heat transport in bulk and nanomaterials based on a kinetic-collective model (KCM). This has become key to understanding the field of thermal transport in semiconductors, and represents an important stride. The book describes how heat transport becomes hydrodynamic at the nanoscale, propagating very much like a viscous fluid and manifesting vorticity and friction-like behavior. It introduces a generalization of Fourier's law including a hydrodynamic term based on collective behavior in the phonon ensemble. This approach makes it possible to describe in a unifying way recent experiments that had to resort to unphysical assumptions in order to uphold the validity of Fourier's law, demonstrating that hydrodynamic heat transport is a pervasive type of behavior in semiconductors at reduced scales.

This book presents some of the latest achievements in nanotechnology and nanomaterials from leading researchers in Ukraine, Europe, and beyond. It features selected peer-reviewed contributions from participants in the 5th International Science and Practice Conference Nanotechnology and Nanomaterials (NANO2017) held in Chernivtsi, Ukraine on August 23-26, 2017. The International Conference was organized jointly by the Institute of Physics of the National Academy of Sciences of Ukraine, Ivan Franko National University of Lviv (Ukraine), University of Tartu (Estonia), University of Turin (Italy), and Pierre and Marie Curie University (France). Internationally recognized experts from a wide range of universities and research institutions share their knowledge and key results on topics ranging from nanooptics and nanoplasmonics to interface studies. This book's companion volume also addresses topics such as energy storage and biomedical applications.

This book features selected papers presented at the 14th International Conference on Electromechanics and Robotics 'Zavalishin's Readings' - ER(ZR) 2019, held in Kursk, Russia, on April 17-20, 2019. The contributions, written by professionals, researchers and students, cover topics in the field of automatic control systems, electromechanics, electric power engineering and electrical engineering, mechatronics, robotics, automation and vibration technologies. The Zavalishin's Readings conference was established as a tribute to the memory of Dmitry Aleksandrovich Zavalishin (1900-1968) - a Russian scientist, corresponding member of the USSR Academy of Sciences, and founder of the school of valve energy converters based on electric machines and valve converters energy. The first conference was organized by the Institute of Innovative Technologies in Electromechanics and Robotics at the Saint Petersburg State University of Aerospace Instrumentation in 2006. The 2019 conference was held with the XIII International Scientific and Technical Conference "Vibration 2019", and was organized by Saint Petersburg State University of Aerospace Instrumentation (SUAI), Saint Petersburg Institute for Informatics and Automation of the Russian Academy of Sciences (SPIIRAS) and the Southwest State University (SWSU) in with cooperation Russian Foundation for Basic Research (project No. 19-08-20021).

This book presents the topology optimization theory for laminar flows with low and moderate Reynolds numbers, based on the density method and level-set method, respectively. The density-method-based theory offers efficient convergence, while the level-set-method-based theory can provide anaccurate mathematical expression of the structural boundary. Unsteady, body-force-driven and two-phase properties are basic characteristics of the laminar flows. The book discusses these properties, which are typical of microfluidics and one of the research hotspots in the area of Micro-Electro-Mechanical Systems (MEMS), providing an efficient inverse design approach for microfluidic structures. To demonstrate the applications of this topology optimization theory in the context of microfluidics, it also investigates inverse design for the micromixer, microvalve and micropump, which are key elements in lab-on-chip devices.

Biology and Engineering of Stem Cell Niches covers a wide spectrum of research and current knowledge on embryonic and adult stem cell niches, focusing on the understanding of stem cell niche molecules and signaling mechanisms, including cell-cell/cell-matrix interactions. The book comprehensively reviews factors regulating stem cell behavior and the corresponding approaches for understanding the subsequent effect of providing the proper matrix molecules, mechanical cues, and/or chemical cues. It encompasses a variety of tools and techniques for developing biomaterials-based methods to model synthetic stem cell niches in vivo, or to enhance and direct stem cell fate in vitro. A final section of the book discusses stem cell niche bioengineering strategies and current advances in each tissue type.

This book was developed with the goal of providing an easily understood text for those users of the scanning electron microscope (SEM) who have little or no background in the area. The SEM is routinely used to study the surface structure and chemistry of a wide range of biological and synthetic materials at the micrometer to nanometer scale. Ease-of-use, typically facile sample preparation, and straightforward image interpretation, combined with high resolution, high depth of field, and the ability to undertake microchemical and crystallographic analysis, has made scanning electron microscopy one of the most powerful and versatile techniques for characterization today. Indeed, the SEM is a vital tool for the characterization of nanostructured materials and the development of nanotechnology. However, its wide use by professionals with diverse technical backgrounds-including life science, materials science, engineering, forensics, mineralogy, etc., and in various sectors of government, industry, and academia-emphasizes the need for an introductory text providing the basics of effective SEM imaging.A Beginners' Guide to Scanning Electron Microscopy explains instrumentation, operation, image interpretation and sample preparation in a wide ranging yet succinct and practical text, treating the essential theory of specimen-beam interaction and image formation in a manner that can be effortlessly comprehended by the novice SEM user. This book provides a concise and accessible introduction to the essentials of SEM includes a large number of illustrations specifically chosen to aid readers' understanding of key concepts highlights recent advances in instrumentation, imaging and sample preparation techniques offers examples drawn from a variety of applications that appeal to professionals from diverse backgrounds.

This book addresses theoretical and experimental methods for exploring microstructured metamaterials, with a special focus on wave dynamics, mechanics, and related physical properties. The authors use various mathematical and physical approaches to examine the mechanical properties inherent to particular types of metamaterials. These include: * Boundary value problems in reduced strain gradient elasticity for composite fiber-reinforced metamaterials * Self-organization of molecules in ferroelectric thin films * Combined models for surface layers of nanostructures * Computer simulation at the micro- and nanoscale * Surface effects with anisotropic properties and imperfect temperature contacts * Inhomogeneous anisotropic metamaterials with uncoupled and coupled surfaces or interfaces * Special interface finite elements and other numerical and analytical methods for composite structures

This book discusses recent advances in hydrogels, including their generation and applications and presents a compendium of fundamental concepts. It highlights the most important hydrogel materials, including physical hydrogels, chemical hydrogels, and nanohydrogels and explores the development of hydrogel-based novel materials that respond to external stimuli, such as temperature, pressure, pH, light, biochemicals or magnetism, which represent a new class of intelligent materials. With their multiple cooperative functions, hydrogel-based materials exhibit different potential applications ranging from biomedical engineering to water purification systems. This book covers key topics including superabsorbent polymer hydrogel; intelligent hydrogels for drug delivery; hydrogels from catechol-conjugated materials; nanomaterials loaded hydrogel; electrospinning of hydrogels; biopolymers-based hydrogels; injectable hydrogels; interpenetrating-polymer-network hydrogels: radiation- and sonochemical synthesis of micro/nano/macroscopic hydrogels; DNA-based hydrogels; and multifunctional applications of hydrogels. It will prove a valuable resource for researchers working in industry and academia alike.

Cyber-Physical and Gentelligent Systems in Manufacturing and Life Cycle explores the latest technologies resulting from the integration of sensing components throughout the production supply chain, and the resulting possibilities to improve efficiency, flexibility, and product quality. The authors present cutting edge research into data storage in components, communication devices, data acquisition, as well as new industrial applications. Detailed technical descriptions of the tools are presented in addition to discussions of how these systems have been used, the benefits they provide, and what industry problems they could tackle in the future. This is essential reading for researchers and production engineers interested in the potential of cyber physical systems to optimize all parts of the supply chain.

The manufacturing industry has experienced dramatic change over the years with growing advancements, implementations, and applications in technology. Manufacturing Intelligence for Industrial Engineering: Methods for System Self-Organization, Learning, and Adaptation focuses on the latest innovations for developing, describing, integrating, sharing, and processing intelligent activities in the process of manufacturing in engineering. Containing research from leading international experts, this publication provides readers with scientific foundations, theories, and key technologies of manufacturing intelligence.