Nuclear magnetic resonance spectroscopy, which has evolved only within the last 20 years, has become one of the very important tools in chemistry and physics. The literature on its theory and application has grown immensely and a comprehensive and adequate treatment of all branches by one author, or even by several, becomes increasingly difficult. This series is planned to present articles written by experts working in various fields of nuclear magnetic resonance spectroscopy, and will contain review articles as well as progress reports and original work. Its main aim, however, is to fill a gap, existing in literature, by publishing articles written by specialists, which take the reader from the introductory stage to the latest development in the field. The editors are grateful to the authors for the time and effort spent in writing the articles, and for their invaluable cooperation. The papers presented here are condensed versions of the main contributions to the 7th Colloquium on Nuclear Magnetic Resonance Spectroscopy, which was made possible by the generous support of the Freunde der Aachener Hoch schule (FAHO). The RWTH is indebted to the FAHO and to all the participants who contributed to the success of the Colloquium."

In 1906, Hermann Leuchs, a student of Emil Fischer, discovered the class of N-Carboxy-aminoacid-anhydrides, also known as Leuch's anhydrides, or abbreviated NCAs. These compounds are, even 80 years after their discovery, valuable intermediates in organic synthesis due to their reactivity: NCAs polymerize with the elimination of carbondioxide to yield polypeptides, model compounds for proteins. They can be used as starting material for a variety of pharmaceutically interesting products and for synthetic polymers (fibres and films). Ralph Hirschmann demonstrated the step by step synthesis of ribonuclease utilizing NCAs as monomers. The author of this monograph, Hans R. Kricheldorf, University Hamburg, is, on account of his own research in Freiburg and Hamburg, predestined to give the reader an insight into the organic chemistry of NCAs and related heterocycles as well as macromolecular chemistry, that is the synthesis of polypeptides and the structure-reactivity relationship. I predict a good accept- ance of this book about the class of cyclic aminoacid derivatives by scientists in various areas. Aachen, September 1986 Helmut Zahn Acknowledgment The author would like to express his gratitude to the american chemical society, the royal society of chemistry, Marcel Dekker Inc., John Wiley & Sons, Hiithig & Wepf Verlag and Kobunshi Gakkai for the permission to reproduce figures from their journals.

The 1992 Chinese Peptide Symposium was held at Hangzhou, China on November 3--6, 1992 with 152 participants, including 46 from abroad, representing 10 countries. The three days conference was both intense and spiritually rewarding. The Biennial Chinese Peptide Symposium was aimed to provide a forum for advancing the exchange of knowledge, cooperation and friendship between the international and Chinese scientific communities. In order to exchange ideas and review the latest progress in depth, the scientific sessions were held at the mornings and evenings, while afternoons were devoted to social interaction and sightseeing of the unparalleled beauty of Westlake. For realizing the goal to catch up with a fast evolving and fascinating field, the Program Committee arranged eight sessions with 45 oral presentations and 72 posters on topics relating to peptide conformation, design, hormone and bioactive peptides, neuropeptides, recognition, synthesis and methodology in the Symposium and selected 94 articles for publication in this proceedings. As an organizer I was greatly encouraged by the active response of invited speakers and moved by enthusiastic cooperation and excellent contributions which led to the great success of the Symposium, since their presentations were of high quality and represented the latest advances in all aspects of peptide chemistry and peptide biology. Many authors concentrated their attention to a great challenge which peptide chemists have nowadays to face, i. e.

Methamphetamine is one of the most widely abused stimulants and together with amphetamine has led to serious social problems. Numerous papers in the fields of medicine, toxicology, pharmacology, sociology, etc. have appeared. In Japan for example about 20,000 to 22,000 persons have been arrested in recent years on suspicion of abuse, smuggling or illegal manufacture of drugs. In other countries, stimulant drugs also present social problems and efforts have been directed toward prevention. Although marked development of analytical techniques in the field of forensic sciences has been achieved, there is a need for a continuous review of recent advances. A review of studies on methamphetamine has therefore been made from the standpoint of forensic toxicology and legal medicine. Attention has been directed to biological samples because analyses and interpretation for the purpose of t.oxicological and As a detailed survey on abuse drugs involving clinical practice are important. 1 methamphetamine and amphetamine has been made by Fishbein and covered the time before 1980, we refer only to data and events appearing after 1980.

Tradi tionally, the International lTV - Conferences on Biomate rials are focussing on problems in Biomedical Engineering, problems, which are still unsolved, of main interest, and which are of interdisciplinary character. In 1983, the Division of Biomedical Engineering of the Institute of Textile Technology and Chemical Engineering, Denkendorf, started wi th a conference about the use of polyurethanes in biomedicine. Three years later, . in 1986, progress in development and use of polyurethanes was selected as conference topic. It had to be realized that degradation problems were still dominating the discussions. The main discussion topics were: What are the causes for the degradation? How can one prevent them? What are the degradation products, and do they affect the human body? How can one simu late the degradation? How can one accelerate the in vitro tests and how can the results predict the in vivo behaviour of the material? How do in vitro tests correlate with animal tests and the behaviour in the human body? At the third conference in 1989, the speakers focused on the use of textiles in medicine. Again the problem of degradation was discussed intensively and demonstrated by the failure of textile implants, the degradation of aramide polymers or the degradation of resorbable suture materials. The examples make clear, that degradation may be a desired or undesired property of an implant."

This book is a collection of the addresses of the keynote speakers and invited lecturers as well as manuscripts of a few outstanding papers which were delivered at the First Pacific Polymer Conference organized by the Pacific Polymer Federation in Maui, Hawaii, 12-15 December, 1989. The First Pacific Polymer Conference covered a wide variety of topics in macromolecular science, demonstrating the emphasis given to polymer research in the Pacific Rim countries. The keynote speakers and invited lecturers are excellent scientists and leaders of effort who covered their fields expertly and in many cases gave their own perspective on the future of polymer science and engineering. A panel discussion on the role of polymers in the arts interested the attendees and emphasized the pervasiveness of polymers in all facets of life. The meeting was attended by over 500 scientists from all over the world. The participants left the meeting with renewed feeling for the importance of polymers in the material sciences and impressed by the progress in polymer research and development. This book, therefore, provides a wide -angle snapshot of the polymer research as we enter the 1990's. It is a useful book for all scientists interested in polymers and the progress of our science in the countries of the Pacific Rim. We hope that many attendees were stimulated by the meeting and that new ideas and new collaborations will result which will further enrich research, and lead to new useful polymers for all countries.

Microbes are known to live in an enormous range of environments. Their ability to survive and proliferate in diverse industrial systems is often a surprise to those not exposed to these problems in their work. These systems contain a range of potential carbon sources, one common theme being surfactants. Surfactants are often not the components most prone to spoilage since some systems contain highly susceptible natural components, such as starch and xanthum gum, but the surfactant is a key part of the formulation, and its extensive breakdown usually means that the material is beyond recovery. The aim of this book is to describe in detail all aspects of the preservation of surfactant containing materials. The book should be viewed as being in three discrete sections. * chapters 1-5 deal with and summarise essential background information * chapters 6-11 discuss in detail various end use applications * chapters 12-15 outline the regulatory and toxicology implication associated with the safe handling of preservatives Given the format of the book there is inevitably some duplication of information in the middle section with different authors describing essentially the same phenomena but on different substrates. I hope the reader will find that although different chapters touch on the same topics the information around these areas is sufficiently different to justify their inclusion in this book and to be of interest. It should also demonstrate what can be the most useful source of information, the hard practical experience of the authors.

Keynote and lectures from invited speakers given at the Se- cond Pacific Polymer Conference in Otsu, Japan, are collec- ted in this book. Eminent Polymer Scientists from both aca- demic and industrial fields around the Pacific Basin contri- buted on the following topics: - Polymer Synthesisand Ractions - Polymer Characterization - Structure-Property-Relationships - High Performance Polymers - Bio-Related Polymers With contributions by H.R. Allcock, R.G. Davidson, T. Inoue, Y.H. Kim, E.A. McCullough, J.E. McGrath, G.F. Meijs, T. Nishi, Y.Nishida, I. Noda, R.M. Nowak, M. Okamoto, R.E. Prud'homme, J.P. Riggs, D.N. Schulz, D.H. Solomon, J. Sunamoto, M. Takayanagi, a.o.

Modern polymer materials are designed by applying principles of correlation between chemical structure, physical macrostructure and technological properties. Fundamentals of polymer physics are explained in this book without excessive use of calculations. Four main sections treat relaxation of polymers, melting and crystallization, the mechanism of deformation in thermoplastics, elastomers and multiphase systems, and thermodynamics of mixing and swelling of polymers and polymer networks. The book presents the theoretical models of polymer physics in a comprehensive style and relates their applicability to real polymer systems in terms of the available experimental observations.

Pedagogical Cases in Physical Education and Youth Sport is a completely new kind of resource for students and practitioners working in physical education or youth sport. The book consists of 20 richly described cases of individual young learners, each written by a team of authors with diverse expertise from across the sport, exercise and movement sciences. These cases bring together knowledge from single sub-disciplines into new interdisciplinary knowledge to inform best practice in physical education, teaching and coaching in youth sport settings. At the heart of each case is an individual young person of a specified age and gender, with a range of physical, social and psychological characteristics. Drawing on current research, theory and empirical data from their own specialist discipline, each chapter author identifies the key factors they feel should be taken into account when attempting to teach or coach the young person described. These strands are then drawn together at the end of each chapter and linked to current research from the sport pedagogy literature, to highlight the implications for planning and evaluating teaching or coaching sessions. No other book offers such a rich, vivid and thought-provoking set of pedagogical tools for understanding and working with children and young people in sport. This is an essential resource for any student on a physical education, coaching, kinesiology or sport science course, and for any teacher, coach or instructor working in physical education or youth sport.

Plastics are used worldwide in everyday life, e.g. as food packaging, electronics, construction, automotive parts, and household appliances. To produce these products with the desired service lifetimes the use of suitable stabilizers is necessary. This book provides a concise and comprehensive overview of the basic mechanisms of plastic degradation processes caused by heat and light. At its core is a detailed description of the stabilization of different polymers, including an explanation of stabilization mechanisms and the influence of commonly used additives such as fillers, flame retardents and pigments on the stability of plastic. Every polymer scientist, material technologist, or application engineer dealing with the design of the properties of plastics will benefit from this new overview.

The fourth Nishinomiya-Yukawa Memorial Symposium, devoted to the topic of dynamics and patterns in complex fluids, was held on October 26 and 27, 1989, in Nishinomiya City, Japan, where ten invited speakers gave their lectures. A one-day meeting, comprising short talks and poster sessions, was then held on the same topic on October 28 at the Research Institute for Fundamental Physics, Kyoto University. The present volume contains the 10 invited papers and 38 contributed papers presented at these two meetings. The symposium was sponsored by Nishinomiya City, where Prof. Hideki Yukawa once lived and where he wrote the celebrated paper describing the work that was later honored by a Nobel prize. The topic of the fourth symposium was chosen from one of the most vigorously evolving and highly interdisciplinary fields in condensed matter physics. The field of complex fluids is very diverse and still in its infancy and, as a result, the definition of a complex fluid varies greatly from one researcher to the next. One of the objectives of the symposium was to clarify its definition by explicitly posing a number of potentially rich problems waiting to be explored. Indeed, experimentalists are disclosing a variety of intriguing dynamical phenomena in complex systems such as polymers, liquid crystals, gels, colloids, and surfactant systems. We, the organizers, hope that the symposium will contribute to the increasing importance of the field in the coming years.

This volume contains the proceedings of the first ISSP International Symposium on the Physics and Chemistry of Organic Superconductors, which was held at the Komaba Eminence Hotel in Tokyo, August 28-30, 1989. This symposium was attended by 205 scientists from 12 countries. In total 106 papers were presented: 61 as posters, and 39 original papers and 6 review papers in oral sessions. Of these, 102 papers are included in these proceedings. These contributions cover the interdisciplinary field of physics and chemistry of organic superconductors with particular emphasis on the following subjects and materials: - superconducting properties, - spin density waves, - electronic and structural properties, - TMTSF salts and their derivatives, - BEDT -TTF salts and their derivatives, - metal coordinated organic conductors. The contributions to this volume are arranged in 11 categories. The Organizing Committee would like to acknowledge all participants, who contributed to the great success of this symposium on a growing field in both physics and chemistry. The editors express their gratitude to the members of the Organizing and Executive Committees for their cooperation. We also wish to thank Dr. H. Lotsch of Springer-Verlag for his management of the publication and Miss S. Shibata for her assistance in editing this volume.

In this volume, the shock compression technology of materials is described in parallel with the latest research results and their background. In the past, this type of technology was developed in connection with military techniques by certain particular research organizations. For this reason, researchers of materials in general have had less opportunity to make use of the technology. The conventional technology of shock compression has now been established, and is recognized as being remarkably useful as a means of materials science study. The feasibility of shock compression technology is dealt with in this book, as well as the latest research results for general material scientists. The shock synthesis of ceramics and intermetallic compounds, as well as shock compression behavior, are also described. In contrast to conventional works of this kind, this book describes shock compression studies performed by material scientists.

This publication presents the proceedings of ICPMSE-4, the fourth international conference on Protection of Materials and Structures from the Low Earth Orbit Space Environment, held in Toronto April 23-24, 1998. The conference was hosted and organized by Integrity Testing Laboratory Inc. (ITL), and held at the University ofToronto's Institute for Aerospace Studies (UTIAS). Twenty two industrial companies, six universities and fourteen government agencies from Canada, USA, United Kingdom, France, Israel, Russia, Ukraine and the Netherlands were represented by over 75 participants indicating increasing international co-operation in this critical arena of protection of materials in space. Twenty-seven speakers, world experts in their fields, delivered talks on a wide variety of topics on various aspects of material protection in space. Representatives from the Canadian, American, European and Israeli space agencies as well as from leading space research laboratories ofmajor aerospace industries gathered at UTIAS to discuss the latest developments in the field of material and structure protection from the harsh space environment.

Polymers continue to show almost amazing versatility. We have always known that polymers could be used for trinkets, toys and dishes. Now, however, we are no longer surprised to encounter these adaptable mate rials in almost every place we look. We find them in our cars, tools, electronic devices, building materials, etc. The use of polymeric mate rials in medicine is also well documented in previous books by one of the Editors (Gebelein) and by others. Likewise, the use of polymeric mate rials in pharmaceutical applications, especially in controlled release systems, is also well established. Nevertheless, the use of these ubiquitous chemicals is far less ob vious in the field of cosmetics, although modern cosmetic preparations rely heavily on polymers and this trend is certain to increase. This book brings together much of the basic information on polymers in cosmetics and compares this usage with similar applications in pharmaceutical and medical applications. Cosmetics, like medicine and pharmacy, dates back to antiquity. We can find uses of perfumes, balms and ointments in various old books, such as the Bible. For example, the use of ointments and balms is noted more than thirty eight times, and perfumes and related materials are cited at least twenty nine times in the Bible."

This volume summarizes the papers presented at the First Osaka University Macromolecular Symposium OUMS'93 on "Ordering in Macromolecular Systems," which was held at Senri Life Science Center, Osaka, Japan, on June 3 through June 6, 1993. The symposium covered the three topics, (1) Crystallization and Phase Transitions, (2) Polymer Liquid Crystals and (3) Block Copolymers, Polymer Blends and Surfaces, and invited leading scientists in these fields. At present any of these topics is a hot issue in itself and frequently taken up separately in many occasions. It is noted however that all these topics are correlated with each other with the keyword "Ordering" and their combination provides a unique feature of the present symposium in reflecting the interactions among investigators working in these important fields with the common ground expressed by the keyword "Ordering." Nineteen invited lectures and 40 posters of both experiment and theory were presented at the symposium, and the eighteen lectures and ten poster presentations contribute to this volume. In the first topic crystal structures and their transitions were discussed from kinetic as well as static points of view; attention was paid to give a molecular-level interpretation of the structure, phase transition and physical properties, using theories and simulations. The second topic was mainly concerned with static structures and thermodynamic properties of polymer liquid crystals including phase behaviours.

''A must for anyone interested in metal-containing polymers and all its aspects.'' ---American Scientist ''Nicely organized...well-written....An excellent shapshot of the current state of this field.'' ---MRS Bulletin, July 1998

Polymeric materials have special advantages over other materials used for the recording, storage and retrieval of information, telecommunication transmission and visualization of images. The authors describe the synthesis, the physico-chemical behavior and the applications of these highly sensitive macromolecular systems. They discuss the most essential developments in this field.
For scientists and professionals working in the field of electrooptical and photooptical polymeric materials.

Progress in Pacific Polymer Science 3 continues the record of the current status of major topics in polymer science.
The invited lecturers cover the following topics:
- Adding Value to Natural Polymers
- Polymers and the Environment
- Polymers in Mining and Mineral Processing
- Multicomponent Polymer Systems
- Characterization, Properties and Processing
- Functional Polymers
- Polymers for Medical Applications
- Polymer Recycling
- Polymer Surfaces of Biological Significance
- New and Advanced Polymer Materials

usage of the terms substrate and substratum. A substrate (pI.: substrates) is a material utilized by microorganisms, generally as a source of energy. A substratum (pI.: substrata) is asolid surface to which a microorganism mayattach. REFERENCES (1) Marshall, K.C. 1976. Interfaces in Microbial Ecology. Cambridge, MA: Harvard University Press. (2) ZoBell, C.E. 1943. The effect of solid surfaces upon bacterial activity. J. Bacteriol. 46: 39-56. Standing, left to right: Paul Rutter, Rolf Freter, Mike Silverman, lan Robb, Hinrich Mrozek, Frank Dazzo, David Gingell Seated, left to right: Garth Jones, Stanislawa Tylewska, Staffan Kjelleberg, Ellen Rades-Rohkohl, Kevin Marshall Microbial Adhesion and Aggregation, ed. K.C. Marshall, pp. 5-19. Dahlem Konferenzen 1984. Berlin, Heidelberg, New York, Tokyo: Springer-Verlag. Mechanisms of Adhesion Group Report P.R. Rutter, Rapporteur F.B. Dazzo H. Mrozek R. Freter E. Rades-Rohkohl D. GingeIl I.D. Robb G.W. Jones M. Silverman 8. Kjelleberg 8. Tylewska K.C. Marshall INTRODUCTION The subject, Mechanisms of Microbial Attachment, has proved to be a fertile sour ce of argument between both microbiologists and physical chemists. In order to find common ground for discussion, the group endeavored to come to a consensus regarding a number of definitions pertinent to the subject. Some of these are described in the text and others will be found at the end of this report.

Diamond-based composites, with their advantages of hardness, high Young's modulus and the like, have demonstrated new and unusual features, such as stability to high temperatures and pressure shocks and a large internal surface that can be controlled to offer customised electrical, magnetic and optical properties, leading to efficient filters, absorbents, sensors and other tools for environmental control and monitoring. The current book covers the synthesis of materials, their characterization and properties, trends in high pressure and high temperature technologies, low pressure technologies, basic principles of DBC material science, and future developments in electronics, optics, industrial tools and components, biotechnology, and medicine. Wide band-gap materials are considered, ranging from molecular clusters, nanophase materials, growth, processing and synthesis. The processing of composite based materials can be classified into six basic methods: in situ growth, high pressure/high temperature catalytic conversion; mix and sinter (c-BN plus metal-ceramic polymer mix); direct sintering; direct polymorphic conversion; shock detonation; and SHS sintering.

These volumes, 7 and 8, of Fracture Mechanics of Ceramics constitute the proceedings of an international symposium on the fracture mechanics of ceramic materials held at Virginia Polytechnic Institute and State University, Blacksburg, Virginia on June 19, 20 and 21, 1985. These proceedings constitute the fourth pair of volumes of a continuing series of conferences. The theme of this conference, as the previous three, focused on the mechanical behavior of ceramic materials in terms of the characteristics of cracks, particularly the roles which they assume in the fracture process. The 78 contributed papers by over 100 authors and co-authors represent the current state of the field. They address many of the theoretical and practical problems of interest to those concerned with brittle fracture. The program chairmen gratefully acknowledge the financial assistance for the Symposium provided by the EXXON Foundation, the Army Research Office, the Natio~al Science Foundation, and the Office of Naval Research. Without their support, this conference simply would not have been possible. The suggestions of Drs. J. C. Hurt, R. C. Pohanka, and L. Toth were particularly helpful in assuring the success of this symposium. Special appreciation is extended to Professor J. I. Robertson, C. P. Miles Professor of History. whose presentation following the banquet on the American Civil War was very well received by the audience. Finally, we wish to also thank our joint secretaries, especially Karen Snider, for their patience and help in finally bringing these proceedings to press.

-Encapsulation by Miniemulsion Polymerization By K. Landfester and C. K. Weiss -Enzyme-Encapsulated Layer-by-Layer Assemblies: Current Status and Challenges Toward Ultimate Nanodevices By K. Ariga, Q. Ji, and J. P. Hill -Non-LBL Assembly and Encapsulation Uses 1 of Nanoparticle-Shelled Hollow Spheres 2 By G.C. Kini, S. L. Biswal, and M. S. Wong -Polymersomes: A Synthetic Biological Approach to Encapsulation and Delivery By M. Massignani, H. Lomas, and G. Battaglia -Reaction Vessels Assembled by the Sequential Adsorption of Polymers By A.D. Price, A.P.R. Johnston, G.K. Such, and F. Caruso

Liquid-crystalline phases are now known to be formed by an ever growing range of quite diverse materials, these include those of low molecular weight as well as the novel liquid-crystalline polymers, such phases can also be induced by the addition of a solvent to amphiphilic systems leading to lyotropic liquid crystals. Irrespective of the structure of the constituent molecules these numerous liquid-cl)'Stailine phases are characterised by their long range orientational order. In addition certain phases exhibit elements of long range positional order. Our understanding, both experimental and theoretical, at the molecular level of the static behaviour of these fascinating and important materials is now well advanced. In contrast the influence of the long range order; both orientational and positional, on the molecular dynamics in liquid Cl)'Stais is less well understood. In an attempt to address this situation a NATO Advanced Study Institute devoted to liquid ctystal dynamics was held at n Ciocco, Barga, Italy in September 1989. This brought together experimentalists and theoreticians concerned with the various dynamical processes occurring in all liquid crystals. The skills of the participants was impressively wide ranging; they spanned the experimental techniques used in the study of molecular dynamics, the nature of the systems investigated and the theoretical models employed to understand the results. While much was learnt it was also recognised that much more needed to be done in order to advance our understanding of molecular dynamics in liquid Cl)'Stais.